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147
resultados
Última actualización
14/08/2025 [07:11:00]
Resultados 25 a 50 de 147
Resumen de: US2025248902A1
The present invention relates to a curable composition for dental purposes. The invention is characterized in that the composition comprises core-shell impact modifiers and 0.1 to 10 wt. % of a binder based on long-chain mono-functional (meth)acrylic acid esters, wherein the ester group has a carbon chain with at least 3 carbon atoms. The invention also relates to the use of the composition as a dental material or a dental auxiliary material, to a dental product made of the composition, and to a method for producing the dental product.
Resumen de: US2025248828A1
The Invention refers to a method for manufacturing a new prosthesis for a lower limb, the method comprising the following steps:a) Providing 3D-data of a prior inner surface of a prior socket and of ist position and its orientation relative to a component adapter, —b) Creating a 3D model of a prosthetic socket with an attachment area for a socket adapter, wherein the prosthetic socket has an inner surface based on the scanned prior inner surface and an outer surface, —c) Determining information about an orientation transmitter, —d) Manufacturing of the prosthetic socket based on the 3D model and providing the orientation transmitter based on the information, —e) Directly or indirectly connecting the manufactured socket to a component adapter by means of the orientation transmitter so that the position and orientation of the inner surface of the prosthetic socket relative to the position and orientation of the component adapter corresponds to the position and orientation of the prior inner surface of the prior socket to the component adapter.
Resumen de: WO2025166116A1
Disclosed are systems and methods for a computerized framework for automated ceramic inkjet printing in dental restoration manufacturing. The disclosed ceramic inkjet mesh printing for dental restorations combines precision digital control with ceramic materials to create highly accurate and aesthetically pleasing dental prosthetics. The disclosed mechanisms utilize specialized printheads designed to deposit precise amounts of ceramic materials onto dental substrates, enabling the creation of detailed color gradients and natural-looking surfaces that closely mimic natural teeth.
Resumen de: WO2025164130A1
Provided are: a curable composition for three-dimensional stereolithography, which contains 100 parts by mass of a polymerizable monomer component (A), 40-400 parts by mass of an inorganic filler (B), 0.01-5 parts by mass of a photoinitiator (C), and 0.01-2.5 parts by mass of an activation light absorber (D), and in which 10-90 mass% of the inorganic filler (B) is contained as an organic-inorganic composite filler (E), the value of light scattering index Sc serving as an index of the proportion of light scattered laterally when being irradiated with activation light is 10% or less, and the rate of transmission for activation light in a state prior to being optically cured is 1-50%; and a method for producing the curable composition for three-dimensional stereolithography. The present invention also provides a method for producing a three-dimensional stereolithographic product and a method for producing a dental restoration article, in both of which said curable composition for three-dimensional stereolithography is used.
Resumen de: WO2025165052A1
The present invention relates to a method for activating natural killer cells, comprising a step of providing electrical stimulation to natural killer cells. Specifically, electrical stimulation under predetermined conditions is applied to natural killer cells by applying an electrical stimulation system established through a 3D-printed electrical stimulation device and a function generator. Here, cancer cell-killing ability and calcium ion-mediated mechanisms are analyzed among induced intracellular effects. In addition, with respect to the natural killer cells produced according to the present invention, a method capable of enhancing the efficacy of a cell therapeutic agent without introducing genetic modification is presented, and the cells can be used to study the correlation between the cancer cell-killing ability and the intracellular calcium ion levels of electrically stimulated natural killer cells.
Resumen de: WO2025166097A1
Disclosed are systems and methods of a decision intelligence (DI)-based computerized framework that automatically and/or dynamically implements a color algorithm for performing staining and glazing dental restorations. The framework operates by leveraging determined color variations through AI/ML-based analysis that generate detailed color maps, which can be translated into precise printing instructions controlling the mixture and layering of dental-grade glazing materials. A printing system can employ multiple print heads with varying base colors and opacity levels to create microscopic color gradients and translucency effects matching natural tooth enamel. The disclosed automated processing applies personalized color patterns in microscopically thin layers, ensuring consistent glaze thickness while replicating regional variations across the tooth surface. Such approach eliminates manual glazing variability while achieving superior customization compared to traditional pre-set patterns, resulting in dental restorations that integrate seamlessly with existing teeth.
Resumen de: WO2025166254A1
A method for manufacturing a ceramic inkjet ink for printing on a dental material substrate includes processing solid particle components to a particle size from 0.8 to 1 μm, at a particle size distribution of D98 and adding an effective amount of additives to the solid particle components to produce the ink capable of being dispensed from an inkjet printhead onto a surface of a 3-dimensional dental material substrate having an irregular shape and uneven surfaces, while the 3-dimensional dental material substrate is simultaneously translated and rotated under the inkjet printhead.
Resumen de: WO2025165300A1
There is provided material for preventing or reducing scar formation during wound healing, the material comprising: (i) a base poly(lactic-co-glycolic acid) (PLGA); and (ii) a bioactive poly(lactic-co-glycolic acid) (PLGA) copolymer, wherein at least part of the material is in the form of a plurality of protrusions extending from a surface. Also provided are a medical device comprising said material, medical uses of said material, and a method of preparing said material.
Resumen de: CN119789957A
The invention relates to a novel silicone foam obtained from a foamable, crosslinkable silicone composition, the invention relates to a composition comprising an organopolysiloxane having at least two silicon-bonded alkenyl groups per molecule, an organosilicon-containing compound having at least two and preferably at least three silicon-bonded hydrogen atoms per molecule, a hydrosilylation catalyst, at least one porogen as water, hydrogel or aqueous silicone emulsion, and at least one surfactant, at least one chemical blowing agent; and a linear polydimethylsiloxane.
Resumen de: CN120051272A
The present invention relates to a process for preparing a solid pharmaceutical administration form comprising an amorphous solid dispersion using a 3D printing process. The process is a printing process which allows the production of solid administration forms of a solid drug comprising an amorphous solid dispersion in a simple and flexible manner and makes it possible to obtain rapidly disintegrating dosage forms with high drug loading.
Resumen de: WO2024069629A1
A 3D-printing support medium is provided herein, comprising hybrid calcium-alginate hydrogel particles and a dispersion medium, formulated by combining calcium-alginate and a soluble polymer distinct from alginate, and the dispersion medium contains a minimum of 2 mM gluconate. These hybrid hydrogel particles possess an average size ranging from 0.1 pm to 50 pm, with exceptional homogeneity characterized by a particle size distribution of less than 50% RSD, resulting in a substantially transparent medium to visible light. The support medium is provided in various forms, including drained particles and slurries with different volume ratios of hydrogel particles to the dispersion medium. The process of preparing this support medium involves forming, pulverizing, washing, and contacting the hybrid hydrogel particles with a gluconate solution, ensuring the presence of gluconate within the hydrogel matrix.
Resumen de: CN120018951A
The present invention relates to a process for the post-treatment of a 3D printed silicone article, said process comprising coating the 3D printed silicone article with a crosslinkable silicone composition comprising a microfiller. The invention further relates to a crosslinkable silicone composition comprising a microfiller, and to the use thereof as a post-treatment composition for post-treating 3D printed silicone articles.
Resumen de: CN120420615A
本申请提供一种近距离放疗模板打印数据确定方法。该方法通过获取目标对象待检测区域的医学影像数据，并根据医学影像数据生成原始放疗模板三维模型，然后，根据待检测区域中目标组织的受体曲面确定施源曲面上的受体区域以及扩散区域，并在原始放疗模板三维模型中生成插植针通道集合，再根据原始放疗模板三维模型以及插植针通道集合生成目标放疗模板打印数据，从而使得所确定的放疗模板打印数据在经过三维打印之后所形成的放疗模板既能利用受体区域实现对当前肿瘤组织的全面覆盖，还能够利用扩散区域实现对肿瘤组织边缘发展的预测匹配，有效地避免了重复进行医学影像采样以及放疗模板制作的复杂过程。
Resumen de: CN120420504A
本发明提供一种髋关节聚氨酯人工盂唇制备方法，将聚氨酯经3D打印制成圆环状聚氨酯支架，随后将圆环状聚氨酯支架表面经过聚多巴胺修饰。本发明一种髋关节聚氨酯人工盂唇制备方法，通过聚多巴胺(PDA)表面修饰技术增强其生物相容性与细胞粘附性，用于修复髋臼盂唇损伤并促进纤维软骨再生。
Resumen de: CN223183653U
本实用新型属于医疗器械技术领域，涉及一种腰椎侧路锁定融合器，包括支撑主体和连接部，所述支撑主体和连接部通过3D打印一体成型，所述支撑主体外形与患者椎体终板相适应，所述支撑主体包括结构区以及贯穿结构区设置的两个植骨区，所述结构区上表面和下表面均设置有齿状结构，所述连接部上设置锁定螺钉以及与锁定螺钉配合设置的防脱件，所述连接部呈中心对称设计，且连接部的上下两端分别设置与锁定螺钉相匹配的螺钉孔，所述防脱件选用卡环，与锁定螺钉转动连接，所述锁定螺钉不突出于患者椎体外缘。本实用新型具有结构简单，操作方便，稳定可靠，能够减少手术时间，降低手术风险等优点。
Resumen de: CN120422391A
本发明提供了一种透超声显影的心脏制备方法，属于生物医学技术领域，包括如下步骤：S1：采集患者心脏CT造影数据；S2：建立患者整体心脏模型；S3：通过已做好的心脏模型制作对应模具，模具分为上下两部分，模具制作完成后，对模具内层进行抛光；S4：向已经抛光后的模具内灌注填充材料，使模具内填充材料固化，固化后去除模具；S5：将模具内的成品取出，并将上下两部分成品闭合连接即得所述心脏模型。本发明制得的心脏模型具有透超声显影功能，方便医生或工作人员进行操作，可广泛应用于医学上的心脏教学、临床上的手术模拟、手术培训和操作练习。
Resumen de: CN120420492A
一种3D打印制备甲基丙烯酰化壳聚糖/明胶基水凝胶创伤敷料的方法及应用，涉及一种制备水凝胶创伤敷料的方法及应用。为了解决现有的MXene光热转化温度高和关闭近红外照射后细菌再次迅速繁殖的问题。本发明ZGC复合水凝胶创伤敷料为多功能集成，能够同时实现止血、抗菌、抗炎、促血管化和细胞再生，尤其适合感染性创面。能够在近红外光的激活下通过光热疗法和光动力疗法的双重作用发挥抗菌性能，同时还能够与Zn2+协同发挥抗菌效果。本发明ZGC复合水凝胶创伤敷料可以通过3D打印技术根据伤口形状和深度精准定制打印，本发明复合敷料可实现精准的低温光热治疗，同时维持Zn2+持续释放和MXene物理抗菌功能，在杀灭细菌的同时保护正常组织，显著提升感染创面愈合率。
Resumen de: CN120424280A
本发明涉及水凝胶技术领域，具体涉及双重固化的水凝胶前驱体溶液、3D打印水凝胶及其应用。双重固化的水凝胶前驱体溶液包括如下重量份的原料：丙烯酸树脂0‑2份，丙烯酸单体8‑10份，热引发剂0.02‑0.05份，水溶性光引发剂0.14‑0.15份和溶剂1‑1.2份；其中，丙烯酸单体包括N‑丙烯酰甘氨酸酰胺和N‑丙烯酰氨基脲；溶剂包括磷酸盐缓冲溶液。本发明提供的水凝胶前驱体溶液制备得到的水凝胶具有优异的拉伸强度和微纳级加工精度。
Resumen de: US2024417501A1
The present disclosure provides a photopolymerizable composition. The photopolymerizable composition includes at least one polypropylene oxide component and an initiator, plus optionally a urethane component, a multifunctional reactive diluent, and/or an inhibitor. The present disclosure also provides an article including the reaction product of the photopolymerizable composition. Typically, the article exhibits an elongation at break of 30% or greater. Further, the present disclosure provides a method of making an article. The method includes (i) providing a photopolymerizable composition and (ii) selectively curing the photopolymerizable composition to form an article. The method optionally also includes (iii) curing unpolymerized polypropylene oxide component, urethane component and/or multifunctional reactive diluent remaining after step (ii). Further, methods are provided, including receiving, by a manufacturing device having one or more processors, a digital object comprising data specifying an article; and generating, with the manufacturing device by an additive manufacturing process, the article based on the digital object. A system is also provided, including a display that displays a 3D model of an article; and one or more processors that, in response to the 3D model selected by a user, cause a 3D printer to create a physical object of an article.
Resumen de: CN120420502A
本发明公开了一种可用于逐层式光固化3D打印的水凝胶微球基生物墨水，属于生物医用和组织工程材料领域。本发明提出了一种含有可光交联的水凝胶微球与少量交联剂(微球可自交联的情况可不加)、光引发剂和光吸收剂组成的生物墨水，在逐层式光固化3D打印中通过水凝胶微球间的光交联反应形成打印结构。该类生物墨水所打印的物件由微球紧密堆积的三维结构组成，微球间的孔隙有效提高了生物墨水的细胞包载能力及生物活性，微球的模块化性可以实现打印复杂异质结构。本发明中的生物墨水具有较小的溶胀性、优秀的打印性能和负载细胞的能力，在负载细胞打印和多材料打印实验中得到了具体应用，具有良好的生物制造及组织工程应用前景。
Resumen de: CN120420518A
本发明公开了3D打印义乳的制备方法，制备步骤包括如下：S1，确定色料：该步骤主要是为确定TPE本色料的颜色。本发明通过3D打印义乳的制备方法实现一种新型的义乳制备方法，通过实现纯TPE材料的3D打印，并且在颜色、大小、形状和香味可供患者选择，从而实现了义乳的个性化定制，满足患者乳腺外观的双侧对称的美学需求，同时弥补了传统义乳按照号码生产，对于过小、过大乳房患者均无合适尺码的问题，同时通过材料的疏水特性，可有效解决透气微孔储水问题，在日常佩戴中可有效做到通风透气，避免汗液潴留，也可以扩展应用场景如温泉、游泳等，极大改善用户的生活质。
Resumen de: CN120422390A
本发明提供了一种透超声皮肤制备方法，属于生物医学技术领域，包括如下步骤：S1：采集患者平扫的胸部CT；S2：重建需要人造皮肤的位置，做出模具；S3：计算需要人造皮肤的容量，配置填充材料；S4：向模具内倒入填充材料，使填充材料固化，然后脱模，即得到透超声皮肤模型。本发明制得的皮肤模型可用在动静脉穿刺上，可以透超声，用穿刺针穿刺后不会漏水，如轻微的漏水可轻微按压漏水的位置，过1分钟左右会缓解漏水的位置，真实的模拟了人皮肤的性质，可以广泛应用在医学教学、临床上的手术模拟、手术培训和操作训练。
Resumen de: CN120420515A
本申请涉及3D打印技术领域，具体涉及了多级仿生3D打印跨尺度复合管腔支架、制备方法及其应用。采用分级调控降解策略，总体结构模拟真实管腔组织结构，面向全生命周期满足物理性能，建立内‑中‑外复合管腔支架，内层为有序纤维层，中层为网状支撑层，外层为无序纤维层，且软组织重建后纤维层实现快速可控降解，避免阻碍内膜重建，为各种管腔疾病的治疗提供更加安全、有效和个性化的解决方案，从而显著提升患者的治疗效果和生活质量。
Resumen de: CN120420603A
本发明涉及电刺激技术领域，公开了基于3D打印面具辅助的面神经炎针灸电刺激治疗系统及方法，包括3D扫描成像设备，用于采集患者面部微观结构信息，并生成面部三维数字化模型；3D打印装置，采用三维数字化模型及大数据，设计并制造与患者面部贴合的3D打印面具；面具上设有穴位定位标识、凹槽、柔性电极及传感器矩阵；智能电刺激主控仪，通过导线与柔性电极连接，用于调控电刺激参数；云端智能决策模块，基于传感器矩阵采集的神经肌电数据，结合深度学习算法生成穴位组合方案及电刺激调控指令。上述的发明，通过对神经肌电数据的采集与深度分析，自动完成针灸穴位定位及电刺激调控，替代针灸师手工操作，实现治疗标准化，提升了治疗效率与效果。
Nº publicación: CN120420503A 05/08/2025
Solicitante:
成都大学附属医院（成都市创伤骨科研究所）
Resumen de: CN120420503A
本发明公开了一种椎间盘髓核支架及其制备方法，属于医疗器械技术领域，其制备方法为：将PLLA、TMC和GA溶解于溶剂中，制得聚合物溶液；将聚合物溶液通过3D打印机逐层打印在冷却平台上，制得内部具有孔隙结构的八棱柱，然后将其进行干燥，制得前驱体；将前驱体进行等离子体处理，制得。该支架具有与人体自身椎间盘相似的力学性能，可减缓力学疲劳；同时，该支架的材料具有良好的生物相容性，且降解产物产生的炎症风险较小，可有效解决现有支架存在的问题。
BOPI
Sede Electrónica
