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一种基于冷冻3D打印的多孔聚醚醚酮/陶瓷复合材料及其制备方法

Resumen de: CN122356557A

本发明提供了一种基于冷冻3D打印的多孔聚醚醚酮/陶瓷复合材料及其制备方法，将PEEK粉末与陶瓷粉末均匀分散于溶剂中，形成复合浆料；将复合浆料在低温冷冻平台上逐层打印，形成以冰晶为模板的预制体；随后经冷冻干燥移除冰晶，再通过程序化的热处理使PEEK颗粒固结，最终获得具有预设三维多孔结构的复合支架。本发明利用冷冻打印过程中冰晶的定向生长与升华，一步成型高精度、高连通性的仿生多孔结构，并实现了陶瓷材料在PEEK基体中的均匀、稳固复合，使支架同时具备较大的孔隙率和良好的力学性能，解决了传统高温发泡加工无法兼容热敏感陶瓷、以及多孔结构调控精度不足的问题。该制备工艺灵活，适用于制造个性化多孔结构与材料。

Mixed-Reality-Ansicht

Resumen de: DE112023006984T5

Computerimplementiertes Verfahren zur Bereitstellung von Anzeigedaten für ein halbtransparentes Durchsichtanzeigegerät in einer medizinischen Umgebung, wobei das Verfahren die Schritte umfasst: Bereitstellen eines 2D- und/oder 3D-Modells eines ersten Objekts (Schritt S1); Empfangen von ersten Positionsdaten des ersten Objekts (Schritt S2); Empfangen von zweiten Positionsdaten eines zweiten Objekts (Schritt S3); Erfassen eines Freiraums basierend auf den zweiten Positionsdaten (Schritt S4); Bestimmen von Anzeigedaten zur Anzeige auf einem halbtransparenten Durchsichtanzeigegerät basierend auf dem 2D- und/oder 3D-Modell, dem erfassten Freiraum, den ersten Positionsdaten und den zweiten Positionsdaten (Schritt S5); und Bereitstellen der bestimmten Anzeigedaten zur Anzeige auf dem halbtransparenten Durchsichtanzeigegerät (Schritt S6).

METHODS AND SYSTEMS FOR DYNAMIC CORONARY ROADMAPPING

Resumen de: US20260191490A1

Methods and systems are provided for dynamically visualizing an object of interest that includes part of the vasculature of a patient, which employ a 3D model of the object to generate at least one roadmap that includes information that characterizes properties of the object (such as centerlines, contours, and an image mask. Reference location(s) corresponding to the roadmap(s) are determined for an interventional device used to treat the object. In an online phase, non-contrast-enhanced x-ray image data of the object are obtained and processed to determine location of the interventional device in the image data, and a particular roadmap is selected or accessed. The reference location corresponding to the particular roadmap and the determined location of interventional device are used to transform the particular roadmap. A visual representation of the transformed roadmap is overlaid on the image data for display.

3D PRINTING OF POROUS MICROFLUIDIC DRUG DELIVERY SYSTEMS

Resumen de: WO2026146019A1

The invention relates to 3D-printed controlled-release solid oral pharmaceutical compositions comprising a hydrophobic matrix comprising cavities filled with air, allowing flotation in the stomach, one or more regions within the matrix comprising a pharmaceutical, one or more regions within the matrix comprising a swellable material, wherein optionally the one or more regions within the matrix comprise a swellable material and a pharmaceutical one or more fracture zones within the matrix with weaker or less dense structure, one or more hydrophilic channels within the matrix fluidly connecting the outside of the composition with a region within the matrix comprising the swellable material or the pharmaceutical.

STRETCHABLE AND HIGHLY CONDUCTIVE CRUMPLED GRAPHENE-BASED FILMS FOR MULTIFUNCTIONAL APPLICATIONS

Resumen de: US20260193139A1

Embodiments relate to a nanocomposite material including a graphene-based 3D porous scaffold coated with active nanoparticles and to methods of making and using the material. The nanocomposite material exhibits high electrical conductivity, mechanical stretchability, and surface roughness, achieved through laser scribing, electrodeposition, and pre-strain transfer printing to induce crumpling. Embodiments further relate to a device including a crumpled nanocomposite material as an electrode and to methods of making and using the device.

MULTIVALENT POLYESTER BASED POLYURETHANE ACRYLATE OR METHACRYLATE OLIGOMERS FORMULATED WITH DIFFERENT REACTIVE DILUENTS

Resumen de: WO2026147879A1

The present disclosure provides novel oligomers and polymerizable compositions comprising the same. Further provided herein are methods of producing polymers, polymer coatings, and devices. Also provided herein are methods of using polymer materials and polymer materials fabricated via additive manufacturing processes (e.g., via 3D printing), such as orthodontic appliances.

SCALABLE FLUIDIC DEVICES FOR HIGH-THROUGHPUT ENRICHMENT AND SEPARATION OF CHARGED SPECIES AND METHODS OF USE

Resumen de: US20260192217A1

The present disclosure relates generally to fluidic devices for high-throughput removal of charged particles from a fluid, for example contaminants from drinking water or contaminants from spent dialysate. The fluidic devices comprise a flow-through 3D ion selective structure within a channel for focusing charged particles along an electric field gradient at the boundary of an ion depleted zone and/or in an ion enriched zone created by the 3D ion selective structure, thereby removing said charged particles from the fluid flowing through the 3D ion selective structure.

SYSTEM FOR CREATING HUMAN TISSUE SAMPLES THROUGH THREE-DIMENSIONAL BIOPRINTING AND CULTURING

Resumen de: WO2026147958A1

This document relates to devices, systems, and methods for fabricating a three-dimensional sample of human tissue. For example, this document relates to techniques for depositing cells according to a predefined pattern and treating the deposited cells to simulate a realistic human tissue sample.

HUMAN BODY MOTION GAIT ANALYSIS USING LIDAR-BASED 3D GAIT MEASUREMENTS

Resumen de: US20260191430A1

In certain implementations a computer-implemented method, computer program product and systems for performing gait analysis using lidar based three dimensional measurements is provided. Embodiments of the present invention can identify at least one object from received video information. Embodiments of the present invention can then estimate points on the object to depict two dimensional and three dimensional poses of the object based on a threshold number of frames depicting the object. Based on the estimated three dimensional poses, embodiments of the present invention can then generate measurements for biomechanical parameters that characterize movement of the object based on the estimated points on the object.

DELAYED-RELEASE ORAL DRUG DOSAGE FORM AND PREPARATION METHOD THEREFOR

Resumen de: WO2026145785A1

A delayed-release oral drug dosage form, and a preparation method related to the oral drug dosage form, such as a three-dimensional printing method.

SYSTEMS AND METHODS FOR MONITORING OXIMETRY PARAMETERS OF TISSUE

Resumen de: US20260191440A1

A system for detecting oximetry parameters of a user may include a reusable, wireless, and flexible near-infrared spectroscopy (NIRS) monitoring wearable system. The NIRS system may include a first component having a plurality of light sources configured to emit visible and infrared light at a plurality of wavelengths. The first component may have a first detector configured to detect a first plurality of signals from the plurality of light sources at a first source-detector distance of approximately 6 millimeters (mm) to 10 mm. The NIRS system may include a second component having a plurality of second detectors configured to detect a second plurality of signals from the plurality of light sources at multiple source-detector distances ranging from about 25 mm to about 45 mm. The NIRS system may include a memory, rechargeable battery, and processor configured to execute multi-depth tissue analysis.

EMERGENCY ALERT MANAGEMENT

Resumen de: US20260191454A1

Systems and methods to improve resource utilization in ambulatory patient monitoring are disclosed, including detecting a critical event using the physiologic information, transitioning the ambulatory medical device from a long-term ambulatory monitoring mode to a critical response mode, and controlling, in the critical response mode, transmission of an advertising packet and information about the detected critical event to a remote device in a continuous listening mode or transition of a communication circuit of the ambulatory medical device to a listening mode to receive an advertising packet of the remote device in a continuous advertising mode to transmit a connection response and information about the detected critical event to the remote device to improve resource utilization of the ambulatory patient monitoring.

SYSTEM AND METHODS FOR A LABOR COACH ALGORITHM

Resumen de: US20260191458A1

0000 Methods and systems are provided for receiving labor-related data for one or more previous contractions of a patient, the labor-related data at least comprising data obtained with one of a tocodynamometer, an IUPC, and an EHG recording system, predicting labor-related data for a next contraction based on the labor-related data for one or more previous contractions, generating one or more visual indicators and one or more audio indicators based on output from a labor prediction model, the output from the labor prediction model being generated by entering the received labor-related data for the one or more previous contractions into the labor prediction model, the predicted labor-related data, and user input into the labor prediction model, and displaying the one or more visual indicators to a display device that is visible to the patient and outputting the one or more audio indicators to the patient.

SYSTEM AND METHOD FOR PROVIDING A DISCRETE WORKSPACE

Resumen de: US20260195728A1

This application describes systems and methods for locating, securing, accessing and utilizing a discrete enclosure or workspace. The discrete enclosure or workspace may be located in a public, private or semi-private setting and may comprise a combination of working platforms or surfaces, seats, desks and other apparatus, as well as computer hardware and software. Systems may comprise natural language processing, artificial intelligence, machine learning and other adaptive learning capabilities to enhance the use of the discrete workspace. The workspace may be dimensioned to be used for a wide variety of activities by one or more users.

SYSTEMS AND METHODS FOR TRAINING MACHINE LEARNING MODELS FOR USE IN A PLURALITY OF SENSORY MONITORING DEVICES

Resumen de: US20260191463A1

0000 Methods and systems for receiving, by at least one processor, for each of a plurality of subjects at defined time intervals during a medical procedure, a subject-specific sensory metric output and a subject-specific sensor dataset. The subject-specific sensory metric output is outputted by a first sensory-monitoring device (SMD) of a first SMD type. The subject-specific sensor dataset is outputted by sensors monitoring a body of each subject from the plurality of subjects, and to be utilized by a second SMD of a second SMD type. The at least one processor executes code to correct for data collection deficiencies, to generate a training dataset for training a machine learning model (MLM) based on the subject-specific sensory metric output and a corrected subject-specific sensor dataset, to train the MLM, and to provide the trained MLM to the second SMD to facilitate medical actions during subsequent medical procedures.

AUTOMATING HIGH QUALITY RADIOTHERAPY PLANNING AT SCALE

Resumen de: US20260192132A1

0000 Systems and methods for generating radiotherapy plans are provided. One or more medical images are received. One or more anatomical objects are segmented from the one or more medical images. Radiotherapy configurations for one or more objectives are determined based on the one or more medical images and the segmentations of the one or more anatomical objectives. A candidate radiotherapy plan is generated based on the radiotherapy configurations. A quality assessment of the candidate radiotherapy plan is performed. The one or more objectives are updated based on results of the quality assessment and the determining, the generating, and the performing are repeated for one or more iterations using the updated one or more objectives as the radiotherapy objectives to generate the candidate radiotherapy plan for a last iteration as a final radiotherapy plan. The final radiotherapy plan is output. Since the pipeline is automatic, the plan generation can be scaled. The data can serve large-scale AI model training.

SUPPORT MATERIAL FORMULATIONS USABLE IN ADDITIVE MANUFACTURING AND METHODS EMPLOYING SAME

Resumen de: WO2026146504A2

A curable formulation usable as a support material formulation in additive manufacturing of a three-dimensional object such as a denture structure, which forms a hardened mixed layer with a modeling material formulation and provides an object that features improved toughness (e.g., fracture toughness), and additive manufacturing methods employing same are provided. The curable formulation comprises at least one non-curable material which comprises at least one polymeric material featuring water solubility (e.g., ECAH) lower than 200 grams/liter, at least one mono-functional (meth)acrylate featuring low Tg and miscibility in the non-curable material, at least one multi-functional (meth) acrylate featuring at least 10 ethoxylated groups and/or Tg lower than 0 °C, and at least one mono-functional (meth)acrylate. Additive manufacturing of a three- dimensional assembly which comprises a hardened object and a hardened sacrificial structure, and systems employing same are also provided.

METHODS AND SYSTEMS FOR PREVENTING CARDIOMETABOLIC DISEASES

Resumen de: US20260191896A1

Some embodiments provide for a method for identifying an intervention for a subject in furtherance of preventing development of cardiovascular disease in the subject, the method comprising: obtaining cardiometabolic health data for the subject; determining, using at least some of the cardiometabolic health data, a first trained machine learning (ML) model and for each of multiple time intervals, one or more measures of risk that the subject develops cardiovascular disease to obtain multiple measures of risk; determining, using the multiple measures of risk that the subject develops cardiovascular disease and at least one second trained ML model, benefit of administering to the subject one or more therapeutic interventions designed to reduce risk of cardiovascular disease by targeting one or more modifiable causes of the cardiovascular disease; and identifying, using the determined benefit of administering the therapeutic intervention(s), at least one therapeutic intervention to recommend being administered to the subject.

METHOD AND SYSTEM FOR CONFIRMATION OF MICRONEEDLE-BASED ANALYTE-SELECTIVE SENSOR INSERTION INTO VIABLE TISSUE VIA ELECTRICAL INTERROGATION

Resumen de: US20260191471A1

0000 A system and method to confirm the insertion of an analyte-selective sensor comprising an array of microneedles possessing vertical extent between 200 and 2000 μm into viable tissue is disclosed herein. Mechanical insertion of an analyte-selective sensor is firstly attempted by means of an application of external force. Either during or following this routine, an electrical stimulus is applied between at least two distinct electrodes located within the said analyte-selective sensor; a resultant response is measured. This response is compared with a reference value to determine if insertion was successful. If insertion was successful, no further effort is required and the sensor can operate as intended. However, if insertion was not successful, the user can be instructed to continue to apply additional force to said sensor to achieve successful insertion or otherwise re-apply the said sensor altogether.

SYSTEMS AND METHODS FOR RHYTHM RECOGNITION

Resumen de: US20260196350A1

The disclosed systems and methods provide systems and methods for rhythm recognition and the analysis of ECG signals.

MITIGATION OF COMPRESSION EVENT FAILURE FOR CONTINUOUS GLUCOSE MONITORS

Resumen de: AU2024395288A1

Certain aspects of the present disclosure relate to methods and systems for distinguishing between temporary compression of a sensor of a continuous analyte monitoring system and failure of the sensor, such as due to detachment of the sensor. In certain aspects, an apparatus includes an analyte sensor, a temperature sensor, a memory, and a processor communicatively coupled to the memory. The processor is configured to evaluate samples of an output of the analyte sensor and samples of an output of the temperature sensor with respect to a threshold condition. If the threshold condition is met, the processor is configured to generate a signal indicating failure of the analyte sensor.

INTERACTION METHOD, DEVICE AND MEDIUM

Resumen de: WO2026145316A1

An interaction method, device and medium are disclosed. The method includes: obtaining first teeth digital model groups respectively corresponding to M orthodontic treatment stages of a patient and a quantity of actual worn steps corresponding to each of the orthodontic treatment stages, where a first teeth digital model group of a first orthodontic treatment stage includes a first teeth model and first designed teeth models respectively corresponding to N orthodontic treatment steps; and in response to an operation of presenting a multi-stage orthodontic treatment plan of the patient, displaying a first orthodontic treatment interface, where the first orthodontic treatment interface includes second teeth digital model groups respectively corresponding to K orthodontic treatment stages sequentially arranged according to a first timeline, a second teeth digital model group of the first orthodontic treatment stage includes the first teeth model and first designed teeth models respectively corresponding to L orthodontic treatment steps.

RESIN COMPOSITION FOR 3D PRINTING, METHOD FOR PREPARING SAME, AND TRANSPARENT ALIGNER COMPRISING SAME

Resumen de: WO2026146775A1

The present invention relates to a 3D printing resin composition for a transparent aligner, a method for preparing same, and a transparent aligner formed by 3D printing using same, the composition comprising 5-20 wt% UDMA (urethane dimethacrylate), 40-70 wt% BIS-GMA (bisphenol A-glycidyl methacrylate), 8-30 wt% BIS-EMA (ethoxylated bisphenol A dimethacrylate), 2-5 wt% TEGDMA (triethylene glycol dimethacrylate), 8-9 wt% modified PVA powder, 5-9 wt% of a filler, 0.72-3.7 wt% of a curing agent, and 0.1-1.0 wt% of an additive, wherein the transparent aligner can be modified to have a structure optimized for the oral cavities of individual users, and thus can maximize the aligning effect.

SYSTEM AND METHOD FOR TITRATING BASAL INSULIN DOSES

Resumen de: US20260192048A1

0000 A continuous glucose monitor (CGM)-driven basal insulin titration system and method for patients with Type 2 Diabetes can be adapted to the needs and concerns of subjects just starting on basal insulin therapy. The method uses as inputs historical CGM data, basal insulin dose information, reports of hypoglycemia, and past recommendations and generates an adjusted insulin dose along with a report advising whether to continue the titration process, or to stop. The method can generate a new recommendation on a regular basis (e.g., each day) until it determines an adequate, consistent dose size.

PULMONARY HEALTH MANAGEMENT DEVICE

Nº publicación: US20260192061A1 09/07/2026

Solicitante:

PNEUMA RESPIRATORY INC [US]
PNEUMA RESPIRATORY, INC.

Resumen de: US20260192061A1

An inhalation device includes a housing defining an air flow channel, a pressure sensor configured to detect air flow within the air flow channel, and a piezoelectric driven ejector configured to eject droplets of a fluid into the air flow channel. A controller is electrically coupled to the pressure sensor and the piezoelectric driven ejector. During an initialization phase in which a user takes a set number of deep breaths, the controller determines a trigger point based on measured inhalation flow. The pressure sensor generates a peak inspiratory flow measurement based on a minimum pressure during inhalation and a pulmonary output based on a maximum flow achieved during exhalation. During a dosing inhalation, the controller actuates the piezoelectric driven ejector when the trigger point is reached to dispense a dose of the fluid. The device may further generate pulmonary health management information based on inspiratory and expiratory flow measurements.