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472
resultados
Última actualización
31/07/2026 [07:10:00]
Resultados 450 a 472 de 472
Resumen de: US20260183092A1
Embodiments relate to a systems and methods for preventative irradiative dental treatment. In accordance with one embodiment, a system and method include using a radiation source to generate a radiation; using an optic disposed to accept the radiation to internally reflect he radiation at a first end; using at least one side of the optic to contact a dental hard tissue; using the optic to couple some of the radiation into the dental hard tissue; and, using a controller to control a parameter of the radiation to heat a surface of the dental hard tissue.
Resumen de: US20260188486A1
0000 According to an embodiment of the present disclosure, disclosed is a method for evaluating qualities of electrocardiogram data and diagnosing a disease only with a signal having an excellent quality. Specifically, according to the present disclosure, a computing device evaluates qualities of electrocardiogram data obtained from a plurality of leads, excludes electrocardiogram data obtained from at least one lead among the plurality of leads based on the evaluation of the qualities of the electrocardiogram data, and performs electrocardiogram analysis based on remaining electrocardiogram data by using a pre-learned electrocardiogram analysis model.
Resumen de: US20260189908A1
0000 Systems and methods for continuous measurement of an analyte in a host are provided. The system generally includes a continuous analyte sensor configured to continuously measure a concentration of analyte in a host and a sensor electronics module physically connected to the continuous analyte sensor during sensor use, wherein the sensor electronics module is further configured to directly wirelessly communicate sensor information to one or more display devices. Establishment of communication between devices can involve using a unique identifier associated with the sensor electronics module to authenticate communication. Times tracked at the sensor electronics module and the display module can be at different resolutions, and the different resolutions can be translated to facilitate communication. In addition, the frequency of establishing communication channels between the sensor electronics module and the display devices can vary depending upon whether reference calibration information is being updated.
Resumen de: EP4769427A1
This application discloses a method and device for detecting an anomaly of a signal from a physiological parameter detection apparatus, particularly a continuous glucose monitor, CGM, comprising: acquiring a working parameter of the physiological parameter detection apparatus, wherein the working parameter comprises a working current; determining whether the signal from the physiological parameter detection apparatus is abnormal based on the working parameter: and outputting a detection result. Through the foregoing solution, an anomaly of a signal from the physiological parameter detection apparatus can be effectively detected, thereby ensuring signal accuracy.
Resumen de: EP4767991A1
Embodiments relate to the methodology of direct manufacture of a customized labial/lingual orthodontic tube by using a ceramic slurry-based additive manufacturing (AM) technology. For example, a method of manufacturing customized ceramic labial/lingual orthodontic tubes by additive manufacturing may comprise measuring dentition data of a profile of teeth of a patient, based on the dentition data, creating a three-dimensional computer-assisted design (3D CAD) model of the patient's teeth, and saving the 3D CAD model, designing a virtual 3D CAD tube structure model for a single labial or lingual tube structure based upon said 3D CAD model, importing data related to the 3D CAD tube structure model into an additive manufacturing machine, and directly producing the tube with the additive manufacturing machine by layer manufacturing from an inorganic material including at least one of a ceramic, a polymer-derived ceramic, and a polymer-derived metal.
Resumen de: WO2025040266A1
The present invention relates to a hybrid supramolecular biomaterial for bioprinting and cell culture, wherein the composition is comprised of functionalized proteinaceous biopolymer and/or polysaccharide biopolymer. The present invention further relates to a biological scaffold comprised of hybrid supramolecular biomaterial and methods for the production of a hybrid supramolecular biomaterial. The present invention furthermore relates to the use of the hybrid supramolecular biomaterial for cell culture, organoid culture and/or bioprinting.
Resumen de: WO2025042300A1
Process for methacrylation of dECM comprising placing a carbonate buffer with a concentration of 1M in the reaction vessel and heating to a temperature of 50 °C, adding dECM to the carbonate buffer to obtain a dECM solution with a concentration of 4% (w/v), sterilizing this solution by irradiation with radiation UV for 15 minutes, adding methacrylic anhydride in an amount of 0.5 mL/1g dECM and reacting at 50 °C for 1 h, then adding a phosphate-buffered saline solution to obtain a 5-fold dilution of the mixture, placing the obtained solution in dialysis tube, and then placing the dialysis tube in deionized water, this stage is carried out at a temperature of 40 °C for no longer than 4 days, after completing this stage, the solution contained in the dialysis tubes is transferred to aluminum trays and then placed at a temperature -80 °C for at least 3 hours, then the frozen solution is freeze-dried under the following conditions: shelf temperature 10 °C, pressure 0.1 mba, freeze-drying time 48 hours. The invention also relates to methacrylated dECM obtained by the above method and to the use of methacrylated dECM obtained by the above method in the bioprinting process.
Resumen de: US2025064727A1
0000 In this specification, a new design and formulation of an expandable, gastroretentive fibrous dosage form is presented where the post-expansion mechanical strength and the drug release rate can be independently controlled. The dosage form generally comprises a fluid-absorptive, three-dimensional structural network of one or more fibers, a mechanically strengthening semi-permeable layer substantially encapsulating said fiber network, and a drug-containing solid attached to said encapsulated network.
Resumen de: EP4768054A2
An infusion pump is secured within a lockbox configured to enclose and prevent access to the infusion pump and a medication receptacle of the infusion pump, the lockbox including a lockbox control interface configured to obtain authorization for access to the lockbox from a pump communication interface of the infusion pump and enclosed within the lockbox. The lockbox control interface is electronically coupled with the pump communication interface. Transmission of a wireless credential is made to the pump communication interface by way of being received at the lockbox control interface or at the pump interface through the lockbox. The lockbox control interface receives the authorization from the pump communication interface for access based on the wireless credential and performs an action according to the received authorization for access. Action includes unlocking the lockbox or the lockbox control interface extending the pump's interface to the authorized user.
Resumen de: GB2702871A
Automatically validating quality data of at least a digital slide 110, 118 scanned by an optical device. The slide is identified 122 with metadata 120 and object detection 128 locates the stained core. The data from the stained core is aligned into a standard form 132 and evaluated against a threshold 134. The stained core is compared to a control core 136 to generate the validation output 138 which is transmitted to a downstream device 140. Generating the validation output may use a stain statistical model 142 to compute the threshold value and may include cross validating 170 a positive control core 164 to confirm. Further a reliability of the validation output may be obtained. This requires configuring one or more optical device parameters comprising a magnification level and a scanning speed of the optical device as a function of the stained core of interest and the positive control core. Figure 1
Resumen de: WO2025008779A1
The present invention relates to an advanced medication containing chitosan and azelaic acid microspheres. The present invention also relates to a process for producing the advanced medication and the use of the advanced medication in the treatment and/or prevention of skin and mucosal lesions.
Resumen de: EP4767928A1
An electronic device is provided and is communicative with an external electronic device. The electronic device includes a processor and a memory storing instructions. When the processor executes the instructions, the electronic device receives a user's heart rate (HR) and/or heart rate variability (HRV) from the external electronic device, maps the HR and/or the HRV to the user's sleep state, selects one of the HR measured in a first state among the sleep states and the HR measured between a designated time from the user's wake up time and the wake up time as a sleep HR, selects one of the HRV measured in the first state among the sleep states and the HRV measured between the designated time from the user's wake up time and the wake up time as sleep HRV and performs at least one operation based on the sleep HR and/or the sleep HRV.
Resumen de: WO2024258205A1
Provided is an implant comprising a first biodegradable polymer and a second biodegradable polymer, wherein the first biodegradable polymer comprises copolymerized polyhydroxyalkanoate (PHA), and the copolymerized PHA comprises, on the basis of the total weight of the copolymerized PHA, 0.1-50 wt% of a repeating unit derived from 4-hydroxybutyrate (4-HB).
Resumen de: US2025186713A1
A disposable fluid delivery system for an electrostatic applicator. The system includes a nozzle cap including a distal end including a delivery outlet and an open proximal end. A nozzle housing can be included with a proximal inlet end and an open distal end connected to the open proximal end of the nozzle cap. A conductive insert is at least partially positioned between the open distal end and the proximal inlet end and includes a portion of a flow pathway formed at least partially between the nozzle cap, the nozzle housing, and the conductive insert. A high voltage connector is extended at least partially through the nozzle housing and electrically connected to the conductive insert and configured to be in electrical communication with a high voltage module and electrostatically charge fluid contents within the flow pathway.
Resumen de: EP4767990A2
0001 Dental attachment placement apparatuses with one or more replacement attachment systems for providing one or more replacement dental attachments. The replacement attachment systems may include a body that is configured to orient and align the apparatus with respect to the teeth. The apparatus may include one or more primary dental attachments coupled to the body, where the body is configured to position the primary dental attachments adjacent to the teeth for bonding. The replacement system can be configured to replace the primary dental attachments and align replacement dental attachments with respect to the teeth.
Resumen de: US2022395456A1
0001 Disclosed herein are contraceptive medical devices that include at least a polymeric ring, a porous barrier material and an injection molding guide, where the guide may be symmetrical and/or have one or a plurality of planar surfaces, where the device may optionally administer at least one active agent.
Resumen de: WO2020227835A1
Provided herein are composite scaffold biomaterials including two or more scaffold biomaterial subunits, each including a decellularized plant or fungal tissue from which cellular materials and nucleic acids of the tissue are removed, the decellularized plant or fungal tissue having a 3-dimensional porous structure, the two or more scaffold biomaterial subunits being assembled into the composite scaffold biomaterial and held together via gel casting using a hydrogel glue; via complementary interlocking geometry of the two or more scaffold biomaterial subunits; via guided assembly based biolithography (GAB); via chemical cross-linking; or any combinations thereof. Methods for producing such scaffold biomaterials, as well as methods and uses thereof, are also provided.
Resumen de: EP4768248A2
The invention concerns a dental appliance comprising a matrix of printed voxels having a three-dimensional shape of a dental arch for surrounding a set of teeth corresponding to a first teeth alignment of a patient, the shape of the dental arch having a lingual side, an occlusal surface, and a facial side; wherein each voxel includes a deposited material for adhering to an adjacent voxel; wherein the matrix of printed voxels applies a force to one or more teeth of the set of teeth causing the one or more teeth to shift into a second teeth alignment; the matrix of printed voxels comprises first voxels (212) and connected second voxels (230), wherein a number of the connected second voxels (230) separate each first voxel (212), and where the number of connected second voxels (230) determines the rigidity of an aligner (100) in one or more spatial directions, and, when taken together, the first voxels (212) and the number of connected second voxels (230) forms a singular or dynamic material flexural characteristic or elastic modulus.
Resumen de: EP4767954A1
0001 Disclosed in the present invention are an automatic determination method and system for ultrasound ablation balloon apposition. The method comprises the following steps: setting related working parameters; after a balloon moves to a target ablation area, injecting normal saline; measuring a pressure in the balloon and an impedance outside the balloon, and feeding back same to a control system; and determining whether the balloon fits with the wall of a blood vessel well. According to the technical solution of the present invention, a pressure in a balloon and an impedance outside the balloon are measured at the same time and compared with set values and set change ranges, such that accurate and automatic determination of an ultrasound ablation balloon fitting with the wall of a blood vessel is achieved, and it is ensured that ablation operation is started after the ultrasound ablation balloon fits with the wall well, thereby greatly improving the ultrasonic transmission efficiency and the ablation operation effect.
Resumen de: EP4769322A2
An automated method for generating a prosthesis from a three dimensional ("3D") scan data, the method includes generating an intermediate surface of the prosthesis extending toward an outside of a prepared tooth from a margin line of the prepared tooth in the 3D scan data, generating an inner surface of the prosthesis by determining a gap from a surface of the prepared tooth, generating an outer surface of the prosthesis and connecting the outer surface of the prosthesis and the intermediate surface of the prosthesis.
Nº publicación: EP4768918A1 01/07/2026
Solicitante:
SYSMEX CORP [JP]
SYSMEX CORPORATION
Resumen de: EP4768918A1
A sample analyzer (1) comprises: a measurement unit (2) measuring an analyte related to a dementia biomarker contained in a sample collected from a subject, and comprising: a sample dispenser, a first reagent dispenser, a second reagent dispenser, and a detector; a controller (101) comprising a processor and programmed to obtain a measurement value of the analyte based on the light detected by the detector; a storage (102) storing a reference value that specifies an outlier that may be caused by a factor other than dementia; and an output unit (103). The controller is programmed to execute a determination on whether the measurement value is specified as the outlier based on the measurement value and the reference value, generate an analysis result of the dementia biomarker based on the measurement value and a result of the determination, and output the analysis result of the dementia biomarker via the output unit.
BOPI
Sede Electrónica
