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唤醒术中与脑机接口校准多模态手运动同步采集装置

Resumen de: CN122350695A

本发明涉及神经外科术中功能监测、侵入式脑机接口及多模态同步采集技术领域，公开了一种唤醒术中与脑机接口校准多模态手运动同步采集装置，包括：柔性传感指套或指背贴条，固定于患者单根手指或多根手指，其上一体集成有柔性弯曲传感器和局部视觉标记点；薄型任务板，厚度允许其从术中患者手部绑带限制的空隙中塞入，板上设置有全局视觉标定点、压力传感模块及同步发光二极管；控制与采集模块，当检测到设定的运动行为事件时，同时触发三路硬件同步输出，分别向任务电脑输出行为日志、控制同步发光二极管闪烁以及向神经信号采集系统发送TTL事件码。本发明实现了在受限空间下的快速部署，并解决了多模态数据时间对齐精度低的问题。

基于三维重建的慢性阻塞性肺疾病气道变化定量分析系统

Resumen de: CN122367932A

本发明公开了基于三维重建的慢性阻塞性肺疾病气道变化定量分析系统，属于医学影像处理与计算机辅助诊断技术领域，该系统包括影像数据获取模块、气道树重建模块、形态学分析模块、小气道功能评估模块、疾病进展预测模块和结果输出模块，最终生成包含三维可视化图像、形态学参数、小气道功能评估结果及疾病进展预测结果的综合报告；该系统实现全肺气道至第6~7级支气管精准重建、气道形态学参数高精度测量、单次吸气相CT小气道功能间接评估及疾病进展智能预测，为COPD早期诊断、病情评估、个体化治疗与预后判断提供全面影像学支持。

一种基于注视诱导的儿童干眼症无创检测方法及装置

Resumen de: CN122350611A

本发明公开一种基于注视诱导的儿童干眼症无创检测方法及装置，涉及眼科医疗器械技术领域。方法包括:提供Placido、弥散白光和双环红外照明模式，并基于正向反向激励反馈进行视觉引导，同时进行眼表视频录制，进行防抖处理，并捕捉时空特征，得到非侵入性泪膜破裂时间和经优化的泪膜稳定性地形图，进行语义分割和特征提取，得到定量的脂质层厚度数值，利用预设的闭合度阈值比较器，得到不完全眨眼的比例。本发明能够显著延长儿童有效睁眼和稳定注视的时间，可获得极其稳定的微米级眼表视频，集成了NIBUT、LLT和眨眼动力学三大核心指标。

一种3D打印卷绕式骨修复支架的批量制备方法

Resumen de: CN122353908A

本发明属于生物医用材料与骨组织工程技术领域，特别提供了一种3D打印卷绕式骨修复支架的批量制备方法，包括如下步骤，S1：复合材料的制备；S2：制备适用于三维打印的丝材、颗粒料、浆料;S3:多孔片材三维打印；S4：热软化卷绕定型；S5:切段；S6:支架后处理。本发明适用于多种可降解高分子/生物活性无机复合材料体系，在相关材料及流程共同作用下，通过三维打印精确控制支架孔径、孔隙率与空间结构，兼容丝材挤出、颗粒直挤及浆料直写等多种打印供料形式，经“长条多孔片材→卷绕定型→轴向切段”的工艺实现了小型骨支架标准化批量生产，具有孔隙结构可控性好、适合多种打印供料形式、批量化生产效率高、支架结构有利于骨再生、材料体系灵活的优点。

一种基于多点生理特征输入的身体条件等级判定驾驶资格的方法

Resumen de: CN122365174A

本发明提供一种基于多点生理特征输入的身体条件等级判定驾驶资格的方法，涉及机器学习技术领域，S1、基于驾驶员的静态生理功能限制参数，确定第一风险因子；S2、获取驾驶员在VR环境中执行预设驾驶任务时产生的驾驶行为数据，确定第二效能因子；S3、基于第一风险因子和第二效能因子计算补偿效能负荷指数；S4、基于补偿效能负荷指数生成次级扰动的扰动指令；S5、根据微失稳特征的分析结果调整与驾驶资格等级相关联的动态安全评级；本发明通过抽象化决策参数，整合成动态演进的闭环控制；同时驱动虚拟环境与分析算法进行自适应调整的控制思想，将复杂的动态评估过程收敛为精确的动态安全评级，并与准驾驶证等级建立明确的映射关系。

一种即时混合调色喷墨3D打印方法及在义齿制备中的应用

Resumen de: CN122353909A

本发明公开了一种即时混合调色喷墨3D打印方法及在义齿制备中的应用，属于3D打印技术领域。该方法包括：制备添加有磁性颗粒的多种颜色墨水；构建颜色色值‑墨水比例数据库；根据目标颜色检索数据库，确定所需墨水的比例配方；按配方将不同颜色墨水喷射至对应单元；通过磁场驱动磁性颗粒运动，使各颜色墨水即时充分混合，实现精确调色；最后固化成型。本发明通过在墨水中引入磁性颗粒并结合外部动态磁场，解决了喷墨3D打印中多色墨水难以在微米级空间内即时、均匀混合的技术难题。该方法尤其适用于制备具有空间全向、连续自然颜色梯度的义齿，显著提升美学效果。

一种脊柱矫形测量装置

Resumen de: CN122350686A

本发明涉及脊柱矫形技术领域，特别是涉及一种脊柱矫形测量装置。该装置包括支撑立板、电机丝杆导轨、支撑臂、电动线性模组、靠背板及测力组件，支撑立板上设限位开关，电动线性模组驱动靠背板升降，配合可调扶手实现患者姿态限位；电机丝杆导轨、手动丝杆导轨及螺纹丝杆协同调节测力传感器位置，精准对位脊柱待测点；装置可精准采集矫形力数据并传输至外部系统，为个性化脊柱矫形器设计生产提供实测依据。本装置定位精准、测力可靠，适配不同体型患者，操作便捷，有效提升青少年特发性脊柱侧凸矫形测力精度与效率。

一种基于冷冻3D打印的多孔聚醚醚酮/陶瓷复合材料及其制备方法

Resumen de: CN122356557A

本发明提供了一种基于冷冻3D打印的多孔聚醚醚酮/陶瓷复合材料及其制备方法，将PEEK粉末与陶瓷粉末均匀分散于溶剂中，形成复合浆料；将复合浆料在低温冷冻平台上逐层打印，形成以冰晶为模板的预制体；随后经冷冻干燥移除冰晶，再通过程序化的热处理使PEEK颗粒固结，最终获得具有预设三维多孔结构的复合支架。本发明利用冷冻打印过程中冰晶的定向生长与升华，一步成型高精度、高连通性的仿生多孔结构，并实现了陶瓷材料在PEEK基体中的均匀、稳固复合，使支架同时具备较大的孔隙率和良好的力学性能，解决了传统高温发泡加工无法兼容热敏感陶瓷、以及多孔结构调控精度不足的问题。该制备工艺灵活，适用于制造个性化多孔结构与材料。

一种磷酸钙-聚己内酯复合材料支架及其制备方法与应用

Resumen de: CN122351600A

本发明提供了一种磷酸钙‑聚己内酯复合材料支架及其制备方法与应用，其中磷酸钙‑聚己内酯复合材料的制备原料包括聚己内酯、β‑磷酸三钙和羟基磷灰石，所得到的复合支架具有促免疫和调控骨再生的功能。本发明的磷酸钙‑聚己内酯复合材料支架的制备方法是先形成羟基磷灰石/聚己内酯复合薄膜，经破碎后与β‑磷酸三钙再度形成复合溶液的方式，所得到的3D打印复合支架不仅具有良好的机械强度和生物相容性，还同时具有诱导干细胞增殖和成骨分化、诱导巨噬细胞的再生分型极化的功能，可用于调控免疫细胞反应，诱导产生有利于骨生成的骨免疫微环境，进而提升骨再生效果，可用于组织缺损的修复和再生。

一种选区激光熔化的镁合金输尿管支架及制备方法

Resumen de: CN122351603A

本发明涉及医疗器械技术领域，公开了一种选区激光熔化的镁合金输尿管支架及制备方法，包括多孔网状结构，支架表面生成有一层均匀致密的磷酸镁转化膜。支架由选区激光熔化专用镁合金复合粉末制成，粉末由钇、钆、钕、锌、锰、锆和高纯镁原料制成。制备方法包括建立患者三维模型并切片处理；采用复合粉末逐层铺粉并熔化得到毛坯；将毛坯分离并进行打磨；打磨后置于热处理炉中依次进行固溶处理和时效处理；浸没于磷酸水溶液中发生钝化反应原位生成转化膜，最后灭菌包装。通过基体成分设计配合选区激光熔化成型技术与表面钝化膜处理，获得了降解速率可控、抗结壳且具备初期力学支撑能力的镁合金输尿管支架。

具有多层级梯度氮化钛耐磨陶瓷层的钛合金关节植入体及其制备方法

Resumen de: CN122351574A

本发明公开了一种具有多层级梯度氮化钛耐磨陶瓷层的钛合金关节植入体及其制备方法，方法包括对植入体表面进行清洁打磨，并采用三维光学扫描轮廓生成路径；在氮气‑氩气混合气氛箱内，通过分阶段调控激光功率、扫描速度、光斑尺寸及氮气体积分数等工艺参数，利用激光重熔扫描依次构建成分梯度过渡层、深度重熔强化层、浅度重熔强化层及表面致密耐磨层，实现从钛合金基体到表层氮化钛陶瓷的成分、组织与性能连续梯度分布的一体化原位合成。本发明可在保留骨接触面仿生多孔结构的同时，在关节摩擦面形成厚度约200μm、显微硬度≥25GPa、表面粗糙度Ra＜0.2μm的高结合强度梯度氮化钛陶瓷层，显著提升植入体的耐磨性、生物相容性与长期服役稳定性。

腫瘍の進行を考慮したアレイ配置の適応

Resumen de: WO2025003793A1

A computer-implemented method comprising: obtaining a three-dimensional model of a subject, the model comprising voxels; identifying a gross tumor volume for the three- dimensional model, the gross tumor volume representing a current location of a tumor in the subject; identifying a primary clinical target volume for the three-dimensional model, the primary clinical target volume having a larger volume than the gross tumor volume, the primary clinical target volume representing an approximation of the current location of the tumor in the subject; identifying a predictive clinical target volume for the three-dimensional model, the predictive clinical target volume having a larger volume than the primary clinical target volume, the predictive clinical target volume representing a predicted future location of the tumor in the subject; and selecting at least one transducer layout for delivering tumor treating fields to the subject based on the primary clinical target volume and the predictive clinical target volume.

电动植入物递送系统

Resumen de: EP4413958A2

0001 Systems, apparatuses, and methods disclosed herein are provided for a motorized implant delivery system. The delivery system may utilize a processor for control of at least one motor for actuating a delivery apparatus. The delivery system may include sensors configured sense one or more of a condition of the patient's body or a condition of the delivery apparatus. The processor may process the signals provided by the sensors, which may comprise feedback signals to the processor.

带过滤的液滴输送装置

Resumen de: WO2025122635A1

An aerosol delivery device including a liquid supply, an electronically actuated droplet ejector in fluid communication with the liquid supply, and filter media or inertial filter points between the ejector and a droplets outlet to reduce the droplet size distribution of ejected droplets to smaller droplets exiting the droplets outlet.

一种个性化穴位刺激系统的全流程闭环控制方法

Resumen de: CN122351012A

0001 本发明涉及医疗器械技术领域，公开了一种个性化穴位刺激系统的全流程闭环控制方法，包括以下步骤：S1、患者诊疗建档与个性化护具制备阶段；S2、医师辨证处方生成阶段；S3、处方指令下发与刺激执行阶段；S4、治疗数据实时采集与回传阶段；S5、医师疗效评估与辨证复核阶段；S6、处方动态优化与闭环迭代阶段；本发明通过定制化的护具制备工艺与内置隔振结构设计，实现了刺激单元与目标穴位的对位，避免了多刺激单元工作过程中的相互干扰，提升了穴位刺激的精准性与独立性，同时通过多通道独立控制与精细化协同时序设计，可完整实现中医穴位配伍的协同治疗逻辑与传统补泻手法的数字化模拟，充分贴合中医辨证施治的核心诊疗理念。

AUTOMATING HIGH QUALITY RADIOTHERAPY PLANNING AT SCALE

Resumen de: US20260192132A1

0000 Systems and methods for generating radiotherapy plans are provided. One or more medical images are received. One or more anatomical objects are segmented from the one or more medical images. Radiotherapy configurations for one or more objectives are determined based on the one or more medical images and the segmentations of the one or more anatomical objectives. A candidate radiotherapy plan is generated based on the radiotherapy configurations. A quality assessment of the candidate radiotherapy plan is performed. The one or more objectives are updated based on results of the quality assessment and the determining, the generating, and the performing are repeated for one or more iterations using the updated one or more objectives as the radiotherapy objectives to generate the candidate radiotherapy plan for a last iteration as a final radiotherapy plan. The final radiotherapy plan is output. Since the pipeline is automatic, the plan generation can be scaled. The data can serve large-scale AI model training.

授乳支援システム、授乳指導支援装置、授乳指導支援方法、およびプログラム

Resumen de: JP2026115517A

0001 【課題】授乳指導に有効な情報を視覚化する授乳支援システム、授乳指導支援装置、授乳指導支援方法、およびプログラムを提供する。 【解決手段】授乳指導支援装置２００は、乳児の舌運動を示す舌運動指標を取得する第１取得部２０２と、乳児の養育者から取得した情報に基づいた第１授乳指標を取得する第２取得部２０４と、養育者に対して乳児の養育に関するアドバイスを行う専門家から取得した情報に基づいた第２授乳指標を取得する第３取得部２０６と、舌運動指標、第１授乳指標、および第２授乳指標を、同時または異なるタイミングで表示させるための表示画面データを生成して出力する出力部２０８と、を備える。 【選択図】図１

3D PRINTING OF POROUS MICROFLUIDIC DRUG DELIVERY SYSTEMS

Resumen de: WO2026146019A1

The invention relates to 3D-printed controlled-release solid oral pharmaceutical compositions comprising a hydrophobic matrix comprising cavities filled with air, allowing flotation in the stomach, one or more regions within the matrix comprising a pharmaceutical, one or more regions within the matrix comprising a swellable material, wherein optionally the one or more regions within the matrix comprise a swellable material and a pharmaceutical one or more fracture zones within the matrix with weaker or less dense structure, one or more hydrophilic channels within the matrix fluidly connecting the outside of the composition with a region within the matrix comprising the swellable material or the pharmaceutical.

SYSTEM FOR CREATING HUMAN TISSUE SAMPLES THROUGH THREE-DIMENSIONAL BIOPRINTING AND CULTURING

Resumen de: WO2026147958A1

This document relates to devices, systems, and methods for fabricating a three-dimensional sample of human tissue. For example, this document relates to techniques for depositing cells according to a predefined pattern and treating the deposited cells to simulate a realistic human tissue sample.

MULTIVALENT POLYESTER BASED POLYURETHANE ACRYLATE OR METHACRYLATE OLIGOMERS FORMULATED WITH DIFFERENT REACTIVE DILUENTS

Resumen de: WO2026147879A1

The present disclosure provides novel oligomers and polymerizable compositions comprising the same. Further provided herein are methods of producing polymers, polymer coatings, and devices. Also provided herein are methods of using polymer materials and polymer materials fabricated via additive manufacturing processes (e.g., via 3D printing), such as orthodontic appliances.

DELAYED-RELEASE ORAL DRUG DOSAGE FORM AND PREPARATION METHOD THEREFOR

Resumen de: WO2026145785A1

A delayed-release oral drug dosage form, and a preparation method related to the oral drug dosage form, such as a three-dimensional printing method.

HUMAN BODY MOTION GAIT ANALYSIS USING LIDAR-BASED 3D GAIT MEASUREMENTS

Resumen de: US20260191430A1

In certain implementations a computer-implemented method, computer program product and systems for performing gait analysis using lidar based three dimensional measurements is provided. Embodiments of the present invention can identify at least one object from received video information. Embodiments of the present invention can then estimate points on the object to depict two dimensional and three dimensional poses of the object based on a threshold number of frames depicting the object. Based on the estimated three dimensional poses, embodiments of the present invention can then generate measurements for biomechanical parameters that characterize movement of the object based on the estimated points on the object.

STRETCHABLE AND HIGHLY CONDUCTIVE CRUMPLED GRAPHENE-BASED FILMS FOR MULTIFUNCTIONAL APPLICATIONS

Resumen de: US20260193139A1

Embodiments relate to a nanocomposite material including a graphene-based 3D porous scaffold coated with active nanoparticles and to methods of making and using the material. The nanocomposite material exhibits high electrical conductivity, mechanical stretchability, and surface roughness, achieved through laser scribing, electrodeposition, and pre-strain transfer printing to induce crumpling. Embodiments further relate to a device including a crumpled nanocomposite material as an electrode and to methods of making and using the device.

SCALABLE FLUIDIC DEVICES FOR HIGH-THROUGHPUT ENRICHMENT AND SEPARATION OF CHARGED SPECIES AND METHODS OF USE

Resumen de: US20260192217A1

The present disclosure relates generally to fluidic devices for high-throughput removal of charged particles from a fluid, for example contaminants from drinking water or contaminants from spent dialysate. The fluidic devices comprise a flow-through 3D ion selective structure within a channel for focusing charged particles along an electric field gradient at the boundary of an ion depleted zone and/or in an ion enriched zone created by the 3D ion selective structure, thereby removing said charged particles from the fluid flowing through the 3D ion selective structure.

MONITORING SYSTEM ENHANCED WITH MILLIMETER-WAVE SENSING

Nº publicación: WO2026148222A1 09/07/2026

Solicitante:

NOMO INT INC [US]
NOMO INTERNATIONAL, INC.

Resumen de: WO2026148222A1

Methods, devices and systems for monitoring a home or other environments, including detection of activities related to movement of a person within a home environment, are described. An example monitoring system includes a hub device communicably coupled to a plurality of sensor devices deployed in an area and configured to collect sensor data for the area. At least one of the sensor devices includes a millimeter-wave (mmWave) sensing component configured to generate three-dimensional sensor data based on the transmission of mmWave signals, which enables the monitoring system to detect normal and abnormal activities as well as non-activities, within the monitored environment.