Alerta

SYSTEMS AND METHODS FOR DIGITAL REMOTE DELIVERY OF PERSONALIZED CONTINGENCY MANAGEMENT TO OPTIMIZE INDIVIDUALIZED TREATMENT OF SUBSTANCE USE DISORDERS

Resumen de: EP4756821A1

Presented herein are systems and methods for managing data structures for remote monitoring and verification of user devices. A computing system may maintain a data structure including an activity field and a verification field, and determine that activity data generated responsive to the user performing an activity via the application satisfies an activity condition. The computing system may update the data structure to include an activity value and receive verification data. The computing system may update the data structure to include a verification value and execute an operation to update the profile using a token based on the activity value and the verification value. The computing system may improve the efficacy of a medication to address a condition in the user.

INTERMEDIATES OF N-(3-(7H-PYRROLO2,3-DPYRIMIDIN-4-YL)PHENYL)BENZAMIDE DERIVATIVES

Resumen de: EP4755462A2

The invention relates to compounds of the formula (I)or a pharmaceutically acceptable salt thereof, wherein the substituents are as defined in the specification; to intermediates in the preparation of the compounds, to pharmaceutical compositions comprising the compounds and to use of the compounds in the treatment of disease.

TORQUE WRENCH FOR THE DENTAL FIELD

Resumen de: EP4755325A1

Die vorliegende Erfindung betrifft Drehmomentschlüssel für den Dentalbereich, insbesondere in Form einer Dentalratsche, sowie Verfahren zum Herstellen eines solchen Drehmomentschlüssels. Entsprechend wird ein Drehmomentschlüssel (10) für den Dentalbereich vorgeschlagen, umfassend einen Aufnahmekörper (12) zum Bereitstellen einer mechanischen Verbindung zwischen dem Drehmomentschlüssel (10) und einem prothetischen Dentalelement, wobei der Aufnahmekörper (12) eine Rotationsachse (46) des Drehmomentschlüssels (10) definiert, einen ersten Stab (34), welcher sich radial vom Aufnahmekörper (12) erstreckt und mit dem Aufnahmekörper (12) einen Grundkörper bildet, und einen zweiten Stab (14), welcher sich radial vom Aufnahmekörper (12) erstreckt, wobei zumindest ein dem Aufnahmekörper (12) gegenüberliegender längsseitiger Endbereich (20) des zweiten Stabs (14) bei Betätigung in einer ersten Rotationsrichtung relativ zum Grundkörper bewegbar ist. Erfindungsgemäß sind der erste Stab (34) und der zweite Stab (14) monolithisch mit dem Aufnahmekörper (12) gebildet, wobei der zweite Stab (14) eine Aussparung (38) aufweist und wobei der erste Stab (34) im nicht betätigten Zustand des Endbereichs (20) in der Aussparung (38) aufgenommen ist.

STIMULATION DEVICES AND SYSTEMS

Resumen de: EP4756823A2

Described herein are noninvasive electrical stimulation devices, systems and methods for stimulation of the Vagus nerve through its auricular branch to provide beneficial physiological responses in subjects, including alleviation, mitigation or elimination of symptoms of various disorders, including metabolic and inflammatory disorders.

SYSTEMS AND METHODS FOR DETERMINING POSITION OF REGION OF INTEREST

Resumen de: EP4756715A2

The present disclosure relates to systems and methods for positioning a region of interest (ROI). The methods may include obtaining an image of an object captured by an imaging device. The methods may extracting image information of the image. The methods may obtaining feature information of a region of interest (ROI) in the object. The methods may determining position information of the ROI in the image using a positioning model based on the image information of the image and the feature information of the ROI.

DRUG DELIVERY DEVICE RECOGNITION

Resumen de: EP4756836A2

0001 A method of detecting a dose of a medicament administered using a drug delivery device is provided. The drug delivery device comprises a dosage dial and a dialled dose indication notch, the dosage dial comprising a plurality of notches. The method comprises: dialling a dose; determining, after dialling a dose, a distance between the dosage dial and a body of the drug delivery device; detecting the relative position of the dialled dose indication notch and the notches provided on the dosage dial; determining the dialled dose based on the detected distance and the relative position of the dialled dose indication notch and the notches provided on the dosage dial.

DEVICES AND METHODS FOR STENT GRAFT EXTRACTION

Resumen de: EP4755346A2

0001 A device for extracting an endovascular stent graft from a vessel including a cylindrical body and an opening formed in the cylindrical body. The cylindrical body has a first open end, a second open end, and a sidewall surrounding a hollow bore of the cylindrical body. The opening is formed in the sidewall between the first open end and the second open end forming a first ring portion at the first open end and a second ring portion at the second open end. Additionally, a thickness of the sidewall at the first open end tapers toward the opening and wherein a thickness of the sidewall at the second open end tapers toward the opening such that the hollow bore is narrower at each end than at the opening.

DIABETES MANAGEMENT SYSTEM USED IN HOSPITAL

Resumen de: EP4756833A1

The invention discloses a diabetes management system for use in a hospital, including: at least a wearable medical device, a plurality of receivers, a central server and a healthcare provider terminal, the receivers receive the data information transmitted by the medical device and upload it to the central server, and the healthcare provider communicates with the central server and displays or reviews the medical data information through the terminal, as any one of the multiple receivers can receive the data information transmitted by the medical device and upload it to the central server, as a result, the patient's range of motion in the hospital is no longer restricted, which improves the patient's experience and keeps the patient in a comfortable mood, while the healthcare provider is able to know the patient's blood glucose level and/or insulin infusion state in real time through the healthcare provider terminal and deal with the abnormalities in a timely manner, so that the patient's blood glucose level can be maintained at a stable level.

RISK EVALUATION DEVICE, RISK EVALUATION PROGRAM, AND RISK EVALUATION METHOD

Resumen de: EP4756837A1

0001 Provided is a risk evaluation apparatus capable of easily, quickly, and accurately evaluating a risk of a locomotive syndrome. 0002 A risk evaluation apparatus 10 according to a first embodiment of the present invention includes an acquirer 101 that acquires first information correlated with a fat mass of a body and second information correlated with a muscle mass, and a determiner 102 that determines the risk of the locomotive syndrome based at least on the first information and the second information. According to the risk evaluation apparatus 10, the risk evaluation apparatus capable of easily, quickly, and accurately evaluating the risk of the locomotive syndrome can be provided.

DENTAL RESTORATION MOLDS INCLUDING UNITARY MOLD BODY

Resumen de: CN121604935A

A custom tool for forming a dental restoration in an oral cavity of a patient, the custom tool comprising an integrally formed mold body providing a custom fit with at least one tooth of the patient, the integrally formed mold body comprising: an occlusal portion, the occlusal part forms an occlusal surface corresponding to the occlusal surface of the teeth; a mesial proximal portion forming a mesial proximal surface corresponding to the mesial proximal surface of the tooth; and a distal proximal portion forming a distal proximal surface corresponding to the distal proximal surface of the tooth. The mold body is configured to combine with a tooth of a patient to form a mold cavity that encompasses a missing tooth structure of the tooth. The bite portion, the mesial proximal portion, and the distal proximal portion are based on three-dimensional scan data of the patient's oral cavity.

多孔三维半月板支架及包括其的可生物降解医疗器械

Resumen de: WO2025095385A1

The present invention relates to a porous three-dimensional meniscus scaffold and a biodegradable medical device comprising same. According to the present invention, external force applied to the meniscus scaffold can be more reliably and evenly dispersed by appropriately adjusting a ratio of intervals between fibers inside the meniscus scaffold, and thus the biodegradable medical device comprising the meniscus scaffold has greater structural stability.

一种3D打印胎体的漆艺认知康复手把件

Resumen de: CN224320911U

本申请涉及认知康复设备技术领域，尤其是涉及一种3D打印胎体的漆艺认知康复手把件，其包括主体结构和辅助功能组件。主体结构由3D打印胎体基材和漆艺表面装饰层组成，胎体基材内部设空腔与加强筋条，表面设有凹槽与凸起结构；辅助功能组件包括调节模块和连接模块，用于调整形状尺寸及外部固定。本申请通过3D打印与漆艺结合，实现轻量化、个性化定制，降低生产成本和周期，提升结构强度与握持舒适度，同时兼具艺术美感与实用功能，满足用户多样化需求并增强康复效果。

用于骨缺损修复的掺杂锶无机纳米纤维复合3D打印支架及其制备方法

Resumen de: CN122141017A

本发明公开了用于骨缺损修复的掺杂锶无机纳米纤维复合3D打印支架及其制备方法，属于骨缺损修复生物材料领域。制备方法包括硝酸锶溶解于正硅酸乙酯、磷酸、去离子水的混合溶液中，所得SiO2‑SrO溶胶与PVA溶液搅拌混合，静电纺丝，高温煅烧，得SiO2‑SrO纳米纤维膜，切小块高速搅匀分散，加入去离子水高速匀浆，冷冻干燥，与去离子水混合，研磨并冷冻干燥，得到SiO2‑SrO纳米短纤维作为分散相，CS溶液与HA溶液磁力搅匀作为连续相，充分混匀制得生物油墨后3D打印，所得支架冷冻干燥和紫外灭菌，浸入交联剂溶液中交联反应。本发明通过静电纺丝与3D打印结合实现支架宏观与微观双层修复功能，用于骨缺损修复方面。

一种3D打印的嵌合式钛镁合金骨修复体

Resumen de: CN224320787U

本实用新型涉及一种3D打印的嵌合式钛镁合金骨修复体，属于骨修复体领域，解决了现有技术中现有单一钛合金骨修复体弹性模量与人体骨骼差异较大，容易导致应力屏蔽效应，而单一镁合金骨修复体力学强度和耐腐蚀性较差的问题。本实用新型包括钛合金柱体、镁合金结构和镶嵌结构，镁合金结构通过镶嵌结构与钛合金柱体连接；沿钛合金柱体的周向设有多个均匀分布的镶嵌凹槽，镶嵌凹槽的两侧壁均设有定向滑道，镁合金结构设置在镶嵌凹槽中，镁合金结构的两侧均设有限位凸起，限位凸起与定向滑道滑动连接。本实用新型在钛合金柱体中镶嵌镁合金结构，依靠钛合金柱体提供力学支撑，镁合金结构逐渐降解促进骨生长，两者结合有效避免了单一材料的缺陷。

一种关闭拔牙间隙的正畸矫治器及其制作方法

Resumen de: CN122140394A

本发明公开一种关闭拔牙间隙的正畸矫治器，括前牙矫治部、后牙包裹部以及间隙关闭部，所述前牙矫治部整体包裹前牙，所述后牙包裹部单颗包裹后牙，所述间隙关闭部件包括施力部件以及固位部件，所述施力部件包括连接体以及固位部件，所述连接体跨越前牙矫治部与后牙包裹部之间的间隙和/或相邻后牙包裹部之间的间隙，所述固位部件设于前牙矫治部或后牙包裹部的表面，连接体通过固位部件进行固位。同时公开了该种正畸矫治器的制作方法。本发明能够高效关闭拔牙间隙。

EXO-PROSTHESIS OF AN AMPUTATED LIMB FOR A PET AND RELATED PRODUCTION METHOD

Resumen de: WO2026115461A1

A prosthesis (1) of an amputated limb for a pet is disclosed, wherein: it comprises a main body (2) extending longitudinally, which is hollow, which is made in a single piece and which is shaped to receive a stump (3) of an amputated limb (4); the main body (2), in turn, comprises: a first part (5) extending along a first axis (A1) and forming a tubular structure; a second part (6) extending along a second axis (A2) and having a first opening (7); it comprises an end (8) which is connected to the first part (5) and which comprises an external surface (9) arranged to contact the ground during the use of the prosthesis (1) of the limb. Furthermore: the prosthesis (1) of the limb comprises anchoring means (10) which are carried by the second part (6) and which are arranged to anchor the stump (3) of the amputated limb (4) and the main body (2) to each other; the first part (5) and the second part (6) are angularly arranged with respect to each other so that the second part (6) laterally embraces part of the radius and ulna bones of the anterior amputated limb (4) or part of the tibia and fibula bones of the posterior amputated limb (4), and the first part (5) receives the stump (3) of the amputated limb (4) during the use of the prosthesis (1) of the limb.

SYSTEMS AND METHODS FOR TRANSDERMAL DRUG DELIVERY AND MONITORING

Resumen de: WO2026117597A1

The present disclosure provides transdermal drug delivery systems, methods, and platforms. In one example, the smart patch includes a drug-containing layer, a communication interface, and one or more sensors configured to detect a status change of the smart patch to the smart patch, the status change of the smart patch including one or more of removing a packaging from the smart patch and applying the smart patch to skin of the patient. The smart patch further includes a processor communicatively coupled to the one or more sensors and the communication interface, wherein the processor is configured to perform operations including automatically transiting between a plurality of working conditions based on the status change of the smart patch, the plurality of working conditions of the smart patch comprising a hibernation mode, a sleep mode, and a work mode and transmitting smart patch usage data via the communication interface.

METHOD FOR MANUFACTURING COMPOSITE MICRONEEDLE PATCH, AND PATCH FOR INJECTING SKIN CARE SUBSTANCE AND PATCH FOR INJECTING DRUG MANUFACTURED BY USING SAME

Resumen de: WO2026116757A1

The present invention relates to a method for manufacturing a composite microneedle patch having multiple materials by using inkjet 3D printing and micro-molding technology wherein, more specifically, the method comprises: a first step of pouring a flexible polymer solution into a master mold to manufacture a negative replica mold of a microneedle patch; a second step of printing a first hydrogel on a predetermined area of the mold by using an inkjet 3D printer; a third step of printing a second hydrogel on an area where the first hydrogel is not printed in the mold by using the inkjet 3D printer; a fourth step of forming a base plate by applying a polymer solution on the area where the first hydrogel and the second hydrogel are printed; a fifth step of drying the base plate to which the first and second hydrogels and the polymer solution are applied in the mold in an environment of 35-38°C; and a sixth step of separating, from the mold, the base plate on which the first and second hydrogels and the polymer solution have been applied.

INTRAORAL TOMOGRAPHIC SCANNING APPARATUS

Resumen de: US20260151215A1

0000 A method for scanning an intraoral feature of a patient repeats a sequence of energizing a hand-held scanner to direct a penetrating signal for characterizing a surface contour and condition of at least a portion of underlying tissue of the intraoral feature. Returned signal energy from each of the plurality of adjacent scanned locations is processed to obtain tomographic image content and to reconstruct, from the obtained tomographic image content, a 3-D model of the intraoral feature. Further processing identifies one or more normal or abnormal conditions for intraoral tissue at each of the plurality of adjacent scanned locations. Simultaneously during the scanning, the method repeats a sequence of: displaying the reconstructed 3-D model and updating the reconstructed 3-D model from the obtained tomographic image content and reporting the one or more normal or abnormal conditions identified at scanned locations of the intraoral feature.

Navigation System Using Tracked Drill Tip for Intramedullary Nail Locking Guidance

Resumen de: US20260151145A1

A surgical system includes an instrument, tool, position markers, image sensor, and control unit. The instrument is configured to engage anatomical tissue along a trajectory that intersects an anatomical target location. The instrument's distal end engages the tissue. The tool manipulates instrument movements along the trajectory. The markers are disposed on a base surface on the tool. The image sensor is tool-mounted; defines a view field encompassing the base surface, markers, and target location; and transmits a live image stream. The control unit receives the live stream and has a processor that executes machine-readable instructions to identify visual spacing and orientation parameters of the markers in the live stream. The processor also calculates and registers in memory a reference location at the instrument's distal end in a 3D coordinate system and calculates distance offsets between the target and reference locations in the coordinate system and communicates the offsets to a user.

A SYSTEM FOR HIGH PRECISION NEUROSURGERY WITH ADVANCED NEUROIMAGING ANALYTICS

Resumen de: WO2026115480A1

The disclosed system provides an integrated neuroimaging analytics platform for comprehensive preoperative neurosurgical planning, intraoperative neurosurgical guidance and post-operative assessment by processing multimodal MRI (structural, diffusion, functional, and angiography) and CT data. The platform performs detailed anatomical characterization by delineating tumor subregions (peritumoral edema, enhancing tumor, and necrotic core), segmenting brain tissues (gray matter, white matter, and CSF), and executing lobe, cortical/subcortical parcellation. Advanced 3D rendering visualizes tumors alongside critical white matter fibre tracts derived from diffusion MRI, while MRA data is used to segment cerebrovascular structures, and functional MRI analysis identifies eloquent cortices associated with motor, speech, and visual functions. All results are integrated within a user-friendly GUI featuring advanced multiplanar slicing and a smart brush for interactive mask editing, complemented by a speech-to-text engine for streamlined analytical reporting. This comprehensive approach facilitates precise and efficient surgical planning, thereby enhancing patient safety and improving clinical outcomes.

LIGHTWEIGHT PORTABLE MRI ASSEMBLY

Resumen de: WO2026115442A1

A portable assembly for an MRI imaging system has independently adjustable modules of a scanner bore having electromagnets positioned along its inner wall, each electromagnet including a coil assembly. An independent power supply, controlled by a controller, connected to each of the electromagnets includes piezoelectric material and generates pulses of electric current (at a specified frequency and for a specified duration) and an electromagnetic field. Detectors positioned along the inner wall are configured to detect a reflected signal while the tissue of the subject is under an influence of the electromagnetic field, and to transmit the reflected signal for a remote computer system to generate an image, an analysis and/or a diagnosis. Cooling water inside coils may include nanoparticles, be hydrogenated and/or induce a water vortex. The electromagnets may be superconductive at a relatively high temperature and may utilize AI-calibrated frequencies. Images generated may be 3-dimensional and converted to 2-dimensional.

METHODS FOR AUTHENTICATING MEDICATION DELIVERY DEVICES

Resumen de: WO2026117364A1

A medication delivery device configured to authenticate itself to a mobile device is disclosed. The delivery device may comprise a syringe assembly comprising a reservoir holding a liquid medication and a needle, a dose sensor for determining when the syringe assembly has initiated or completed a dose event, a wireless communication device, memory storing computer-executable instructions and a secret encryption key, and a processor. The processor may be configured to detect, using the dose sensor, when the syringe assembly has initiated or completed the dose event; receive a request for information regarding the dose event from the mobile device, the request including a timestamp; and transmit in response an encrypted packet comprising the requested information and the time stamp, wherein the encrypted packet has been encrypted using the secret encryption key.

WEARABLE ELECTRONIC DEVICES AND RELATED SYSTEMS AND METHODS

Resumen de: WO2026117794A1

A wearable electronic airway device for wellness-focused and medical-focused application can integrate adjustable mandibular support for OSA management or sensor-based concussion monitoring. Embodiments can include modular sensors (e.g., PPG, accelerometers), AI analytics, and a companion app with health reports for metrics such as sleep duration, restfulness, average SpO2, resilience, and diagnostic thresholds (AHI, impacts). Embodiments thereby can assist with enhancing health outcomes through non-invasive, AI-enhanced technology.

SYSTEM AND METHOD FOR VERTEBRAL LOCATION PREDICATION IN SPINE SURGERY

Nº publicación: US20260151184A1 04/06/2026

Solicitante:

HWANG RAYMOND WEIHAU [US]
Hwang Raymond Weihau

Resumen de: US20260151184A1

A system and method for predicting spinal motion and vertebral locations and movement in surgeries through training and using predictive models generated using biomedical profiles of patient spines and surgical patient-specific features. A trained predictive model is used in combination with patient-specific features associated with a surgical patient such that during a real-time surgery the patient-specific features are provided to the trained predictive model and a segmental motion model is created. Using this real-time surgical data and interoperative data, the trained predictive model is updated which then used for updating the segmental motion model such that the updated segmental motion model may be used for producing a series of vertebral location predictions specific to movements and location of the spine of the surgical patient that may be provided to a surgical guidance system for use in performing the real-time surgery in accordance with a surgical plan.