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化粧組成物

Resumen de: US2023210752A1

A cosmetic composition including a solvent A, a solvent B, a polymer C and a colorant. The solvent A is at least one selected from the group consisting of ethanol, n-propanol and isopropanol. A boiling point of the solvent B is 150° C. or higher. The solvent B is compatible with the solvent A, and the polymer C is soluble in the solvent A and insoluble in the solvent B. A content of the solvent B is 5% by mass or more and 40% by mass or less, and a ratio by mass of a content of the solvent A to a content of the solvent B solvent A/solvent B in the cosmetic composition is 1 or more and 15 or less.

METHOD OF MANUFACTURING PROSTHETIC SOCKET INTERFACE

Resumen de: US2025190637A1

A method of manufacturing an interface for a body part is described. The method includes the step of selecting an inner radial dimension of the interface to have a plurality of compression areas that extend along the long axis of the interface. The method also includes the step of spacing the plurality of compression areas circumferentially around the long axis of the interface to create a compression pattern. The compression pattern is sized and dimensioned to reduce motion of the skeletal structure towards a wall of the interface when the interface is worn on the body part by compressing soft tissue of the body part against the skeletal structure.

BONE REPAIR MATERIAL, PREPARATION METHOD THEREFOR, AND USE THEREOF

Resumen de: WO2025118246A1

Provided are a bone repair material, a preparation method therefor, and use thereof. The bone repair material is prepared by printing with a material slurry by means of a photocuring 3D printing method and then sintering. The material slurry comprises the following components: 55-65% by mass of bioactive glass, 30-40% by mass of photosensitive resin, 1-5% by mass of a dispersing agent, and 0.1-1% by mass of a photoinitiator. The bone repair material has excellent biocompatibility and relatively high porosity, with the hemolysis rate lower than 5% and the cytotoxicity less than 30%. In addition, the bone repair material has relatively good morphology and relatively superior mechanical properties, and thus can be used as a bone repair scaffold material.

SHAPE MORPHING HYDROGEL ACTUATORS AND CONSTRUCTS

Resumen de: US2025186656A1

A construct includes a biocompatible polymer-based shape morphing hydrogel or cell condensate that is configured to undergo multiple, reversible, and/or controllable different shape transformations over time via either pre-programmed design or user-controlled environmental condition alterations, wherein the hydrogel is cytocompatible and, upon degradation, produces substantially non-toxic products.

BIODEGRADABLE 3D PRINTED STRUCTURE FOR BONE AUGMENTATION

Resumen de: WO2025120338A1

Biodegradable 3D printed structure for bone augmentation (1) comprises an outer structure (100) and an inner structure (200) that are printed from polylactide (PLA), wherein the inner structure (200) is filled with a chitosan and hydroxyapatite gel and the outer structure (100) is coated with a chitosan and hydroxyapatite composite. The outer structure (100) has a tunnel-like shape resembling an elongated projection of the letter "U" rotated 180 degrees in depth. Implants made in the form of a biodegradable 3D-printed structure for bone augmentation as disclosed in the present invention can be adapted to each individual patient and each individual situation, which will optimize the dentist's time required for the procedure and treatment, and will also facilitate the recovery of the patient due to the reduction of the invasiveness of the procedure. This makes the entire procedure faster, simpler, and painless, but also financially acceptable for patients.

PATIENT SPECIFIC SURGICAL GUIDE LOCATOR AND MOUNT

Resumen de: US2025186062A1

A resection guide locator includes a bone engagement portion with surfaces that are complementary to the surface topographies of a bone to be resected during surgery. A housing includes a socket defined by a resilient annular wall that is sized and arranged so to accept a resection guide by press-fit to thereby position and hold the resection guide within the socket. The resection guide is maintained in a predetermined, preferred position while the surfaces are releasably locked in position on the bone. A method is disclosed for forming and using the resection guide locator.

THREE-DIMENSIONAL CELL-LADEN BIOINK SCAFFOLDS AND METHODS OF MAKING THE SAME UNDER CRYOGENIC CONDITIONS FOR TISSUE ENGINEERING

Resumen de: US2025188298A1

The present invention provides three-dimensional, cell-laden bioink scaffolds, methods of making and using the same.

PRINTING MECHANISM FOR MEDICAL MONITORING DEVICE AND MEDICAL MONITORING DEVICE

Resumen de: US2025187357A1

The present invention provides a printing mechanism for a medical monitoring device and a medical monitoring device. The printing mechanism comprises a support plate, a movable frame assembly disposed movably on the support plate. the movable frame assembly comprising a frame, and a print paper drawer for holding the print papers, the print paper drawer being mounted on the frame to move along with the movable frame assembly. The printing mechanism further comprises at least one set of spaced sleeves provided on a top surface of a body of the support plate in a movement direction of the movable frame assembly. and a guide rod passing through holes defined by each set of the spaced sleeves and secured to a bottom of the frame at two ends. the guide rod guiding the movable frame assembly and moving along with the movable frame assembly, wherein a damping bracket is provided between adjacent sleeves of each set of the spaced sleeves, the damping bracket contacts the guide rod and exerts an upward force onto the guide rod perpendicularly to a movement direction of the guide rod. The printing mechanism for the medical monitoring device according to the present invention may ensure that the print paper drawer is positioned with high accuracy and is opened and closed smoothly when the printing mechanism operates in the horizontally arranged state or the vertically hung state.

Photocurable Materials for the Production of Dental Prostheses and Devices

Resumen de: US2025187262A1

A resin based material whose composition includes a light-curable mixture of monomers of no more than 35 wt. % of an ethoxylated difunctional bisphenol A dimethacrylate; of no more than 10 wt. % of a methacrylate monomer; of no more than 10 wt. % of a difunctional urethane acrylate; of no more than 0.1 wt. % of an optical brightener; of no more than 5 wt. % of silica particles having methacrylate functionalization layers and having an average particle size of less than about 200 nm; of having more than 40 wt. % of an inert glass; of no more than 15 wt. % of a heavy metal oxide; of no more than 2.5 wt. % of an ultraviolet/visible (UV/Vis) light-photo-polymerization initiator; a colorant; and a stabilizer.

System and Methods for Preparation of Adipose-Derived Stem Cells

Resumen de: US2025186502A1

A device that allows for either fat graft preparation or cell fraction harvest is disclosed. The device includes a first centrifuge tube configured to receive and process a biological substance, the first centrifuge tube comprising an upper cylindrical portion and a lower conical portion, a sterile tissue inlet fitting, at least one sterile processing fluid inlet fitting, a sterile suction fitting, and at least one sterile extraction port connected to a first extraction tube. The first centrifuge tube further includes an internal space including a screen being positioned therein, the screen being configured to divide the internal space in half, and a filter positioned therein, the filter being positioned below the screen in the lower conical portion of the first centrifuge tube. The device may further include a second centrifuge tube configured to receive and further process the biological substance from the first centrifuge tube. The second centrifuge tube has at least one sterile fitting, wherein the second centrifuge tube is releasably connected via the at least one sterile fitting to one of the at least one sterile extraction ports of the first centrifuge tube.

HYDROGEL-EXTRACELLLAR MATRIX GRANULAR COMPOSITES WITH VISCOUS INTERSTITIUM

Resumen de: WO2025122495A1

Composite matrix materials including a plurality of microgel particles having a mean particle size in a range of about 1 μm to about 100 μpm, and an interstitial matrix, where the composite matrix is characterized by reversible yield-stress behavior at 4°C; methods of preparation of the composite matrix materials; and methods of preparing organoids from the composite matrix materials are disclosed.

Dental and skeletal training aid and method for producing same

Resumen de: GB2636068A

The present invention relates to an artificial tooth 10 or bone formed from a unitary 3D printable material. An artificial tooth comprises an outer enamel-like portion 12 and an inner dentine-like portion (14) having voids therein. The outer layer offers a high resistance to drilling and may be of stereolithography (SLA) resin comprising three parts: Urethane Dimethacrylate (UDMA), Isobornyl Methacrylate (IBMA) and a reinforcing agent, such as glass filler, ceramic powder, carbon or graphene. The dentine layer has foam or sponge-like properties with voids or channels 16 and is of lower resistance to drilling. A pulp layer 18 of e.g., a wax-type material, 3D printing resin, silicone or rubber may be provided to mimic tooth pulp. The printing method may be e.g., a resin-vat stereolithography or a material extrusion method. Simulated bone may be produced in a similar manner. A tooth may be implanted in a phantom head for training purposes.

ELECTROSURGICAL INSTRUMENT WITH MONOPOLAR AND BIPOLAR ENERGY CAPABILITIES

Resumen de: EP4567142A2

An electrosurgical instrument comprising an end effector including a first jaw, a second jaw, and an electrical circuit is disclosed. The first jaw comprises a first conductive skeleton, a first insulative coating selectively covering portions of the first conductive skeleton, and first-jaw electrodes comprising exposed portions of the first conductive skeleton. The second jaw comprises a second conductive skeleton, a second insulative coating selectively covering portions of the second conductive skeleton, and second-jaw electrodes comprising exposed portions of the second conductive skeleton. The circuit is configured to transmit a bipolar RF energy and a monopolar RF energy to the tissue through the first-jaw electrodes and the second-jaw electrodes. The monopolar RF energy shares a first electrical pathway and a second electrical pathway defined by the electrical circuit for transmission of the bipolar RF energy.

METHOD FOR PRODUCING A DENTAL RESTORATION

Resumen de: US2024299144A1

A method of producing a dental restoration (100), including the steps of calculating (S101) a pressure distribution (101) on the oral mucosa (105) through the dental restoration (100) based on a three-dimensional data set (103-DS) of the dental restoration (100) and a three-dimensional data set (103-MS) of the oral mucosa (105); and determining (S102) a spatial region (107) for an elastic production material (109) within the dental restoration (100) based on the calculated pressure distribution (101).

BIODEGRADABLE 3D PRINTED STRUCTURE FOR BONE AUGMENTATION

Resumen de: EP4566637A1

Biodegradable 3D printed structure for bone augmentation (1) comprises an outer structure (100) and an inner structure (200) that are printed from polylactide (PLA), wherein the inner structure (200) is filled with a chitosan and hydroxyapatite gel and the outer structure (100) is coated with a chitosan and hydroxyapatite composite. The outer structure (100) has a tunnel-like shape resembling an elongated projection of the letter "U" rotated 180 degrees in depth. Implants made in the form of a biodegradable 3D-printed structure for bone augmentation as disclosed in the present invention can be adapted to each individual patient and each individual situation, which will optimize the dentist's time required for the procedure and treatment, and will also facilitate the recovery of the patient due to the reduction of the invasiveness of the procedure. This makes the entire procedure faster, simpler, and painless, but also financially acceptable for patients.

PHARMACEUTICAL FORMULATION PRINTING DEVICE

Resumen de: US2019276239A1

Provided is a pharmaceutical formulation transporting device capable of easily ensuring a large exposed area of a solid pharmaceutical formulation during transport. A pharmaceutical formulation transporting device 10 comprises a first pulley 11, a second pulley 12, and a plurality of endless transport belts 13, 14 wound around the first pulley 11 and the second pulley 12, wherein the plurality of transport belts 13, 14 are disposed so as to be capable of holding a solid pharmaceutical formulation between respective first side surfaces.

プログラム、３次元データ設計装置、３次元データ設計方法および３次元データ設計システム

Resumen de: JP2025088292A

【課題】歯型の模型の形状に依存せず、レジンが外れにくい義歯（前装冠）の３次元データを生成する。【解決手段】コンピュータに、歯型の３次元データに応じた３次元歯型モデル上で、ビーズ状の構造体を配置する範囲または箇所の指定を受け付ける配置範囲受付部と、前記配置範囲受付部で指定を受け付けた範囲または箇所に基づいて、前記３次元歯型モデル上で前記ビーズ状の構造体を所定間隔にて配置する配置部と、前記配置部によって配置された前記ビーズ状の構造体の３次元データと前記歯型の３次元データとを出力する出力部と、を実現させるためのプログラムである。【選択図】図６

セラミック多色インクジェット３Ｄ印刷における硬度および半透明性の選択的な調節

Resumen de: US2025170750A1

A method of producing a dental restoration by jet-printing, comprising the steps of jet-printing (S101) one or more layers of the dental restoration by means of a ceramic slurry; and jet-printing (S102) a translucency enhancer or opacity enhancer onto the one or more layers.

セラミック多色インクジェット３Ｄ印刷のための予着色されたスラリ

Resumen de: US2025171364A1

A method of producing a dental restoration by jet-printing, including the steps of jet-printing (S101) a dentin core of the dental restoration using a plurality of opaque ceramic slurries having different colors from each other; and jet-printing (S102) the tooth enamel of the dental restoration using a translucent ceramic slurry.

３Ｄ印刷における着色溶液を使用した選択的着色

Resumen de: US2025170648A1

A method of producing a dental restoration (100) by jet printing, including the steps of jet printing (S101) one or more layers of the dental restoration using a ceramic slurry; and jet printing (S102) a coloring solution onto the one or more layers.

一种3D打印的、具有多功能梯度的仿生压电支架、制备方法及应用

Resumen de: CN120114649A

本发明涉及生物医学工程领域，具体涉及一种3D打印的、具有多功能梯度的仿生压电支架，包括3层支架层和1层仿生结构层，仿生结构层置于支架层上，仿生结构层由PDMS阴模翻制为仿生结构，浸泡三氯十八烷基硅烷溶液后得到；支架层在仿生结构层表面，由不同组成的生物墨水经墨水书写式3D打印技术逐层打印得到，生物墨水是将聚(3‑羟基丁酸酯‑co‑3‑羟基戊酸酯)、海藻酸钠和丙烯酰胺加入水、DMF和CH2Cl2配制成的溶剂，再加入光引发剂和交联剂制备得到，仿生压电支架，具有良好的生物相容性、促进肌腱修复、抗炎和抗菌的功能环境，可以有效促进肌腱干细胞增殖与迁移，促进肌腱干细胞诱导分化，为缺损肌腱的修复再生提供物理屏障，具有广阔的应用前景。

一种具有离子释放和光热介导双模式抗菌的3D打印聚乳酸复合支架的制备方法和应用

Resumen de: CN120114644A

本发明公开了一种具有离子释放和光热介导双模式抗菌的3D打印聚乳酸复合支架的制备方法。该方法将聚乳酸(PLA)颗粒、氮化硼(BN)和氧化锌(ZnO)通过溶剂铸造的方式混合搅拌均匀制备成复合片状材料，使用单螺杆挤出机将复合片状材料制备成复合丝材，将制备的复合丝材通过熔融沉积成型(FDM)3D打印技术制备聚乳酸/氮化硼/氧化锌(PLA/BN/ZnO)复合支架，之后在其表面涂覆了负载了银纳米颗粒聚多巴胺涂层，最后得到具有离子释放和光热介导双模式抗菌的3D打印聚乳酸复合支架。通过本发明提出的方法制备的支架具有PDA涂层光热介导抗菌和外层银离子释放、内层锌离子释放梯度抗菌双模式抗菌功能，同时氮化硼的加入使得支架促成骨性能得到提升。本发明为骨缺损修复过程中常见的细菌感染问题提供了一种有前景的解决方案。

3D打印的下颌前移阻鼾器

Resumen de: CN120114246A

本发明公开了3D打印的下颌前移阻鼾器，本发明涉及阻鼾技术领域，包括上牙槽和下牙槽，所述上牙槽和下牙槽均通过3D打印而成；所述上牙槽和下牙槽的周边处均匀设置有安装块；所述下牙槽的两端后侧均设置有支撑块，所述安装块和支撑块均通过3D打印而成；通过放在用户周围的噪音传感器检测用户的鼾声，当用户打鼾时，通过控制器和信号发射器控制电动伸缩杆工作，使得输出杆推动导杆移动，进而通过销轴一和销轴二，使得下牙槽向前移动，推动下颌前移，扩大呼吸通道，以阻止打鼾，从而可以在睡着后打鼾时再进行调节，避免用户在初期使用时，出现带着调节好后的阻鼾器往往难以进入睡眠状态的问题。

一种负载干细胞外基质的3D打印材料及其制备方法和应用

Resumen de: CN120114650A

本发明提出了一种负载干细胞外基质的3D打印材料及其制备方法和应用，属于生物材料技术领域。包括如下重量份的组分：改性丝素蛋白肽‑聚乳酸树脂100‑150份、负载干细胞外基质纳米粒子20‑40份、缓释壳聚糖微球10‑20份、透明质酸钠150‑200份、明胶50‑100份。本发明制得的负载干细胞外基质的3D打印材料与传统化学合成高分子支架相比具有更好的生物相容性，安全性高，力学性能佳，促进了细胞的粘附生长，实现了药物的缓慢均匀释放，多信号调节软骨生长和骨化，促进了软骨修复，具有广阔的应用前景。

セラミック多色インクジェット３Ｄ印刷における着色溶液の固定

Nº publicación: JP2025087616A 10/06/2025

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イボクラールビバデントアクチェンゲゼルシャフト

Resumen de: US2025169929A1

A method of producing a dental restoration by jet-printing, including jet-printing one or more layers of a dental restoration using a ceramic slurry, jet-printing a coloring solution onto the one or more layers, and applying a fixing solution for fixing the coloring solution.