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511
resultados
Última actualización
22/10/2026 [09:56:00]
Resumen de: EP4825318A1
0001 The present disclosure provides a method and a computing device for setting a treatment order based on an emergency patient's condition. According to an embodiment of the present disclosure, a method for setting a treatment order based on an emergency patient's condition, performed by a computing device including at least one processor, comprises, when reception data of a new examinee is acquired, acquiring physiological data of the examinee via a sensing unit, analyzing the physiological data using a pre-trained neural network model to identify the new examinee's condition, and setting a treatment order for the new examinee based on a time at which the reception data of the new examinee is acquired and the new examinee's condition. The setting of the treatment order comprises setting the treatment order for the new examinee by adjusting, based on the examinee's condition, the treatment orders of the other previously registered examinees who are waiting for treatment.
Resumen de: WO2025128987A1
Described are continuous manufacturing methods using 3D printing or any similar additive manufacturing technology to produce pharmaceutical ASDs. Manufacturing methods include preparing printing ink including API and polymeric carriers. The printing ink is accurately deposited onto a deposition surface by forming printing ink droplets by using an electromagnetic DoD 3D printing device to form an ASD printed product. The ASD printed product has improved solubility and bioavailability than the API in crystalline form.
Resumen de: EP4826734A2
0001 Embodiments of delivering reduced pressure wound therapy are disclosed. In some embodiments, a system includes a reduced pressure wound therapy device and a remote computer. The device can be configured to apply reduced pressure to a wound of a patient according to a default reduced pressure therapy prescription. The device can be configured to monitor usage data and transmit the usage data to the remove computer for determining compliance with a reduced therapy prescription. In some cases, non-compliance can be determined due to change of the prescription from the default prescription to a prescription more suitable for treating the wound. A non-compliance notification can be transmitted to the device. The device settings can be updated to the current prescription.
Resumen de: EP4825410A2
0001 An administration system for delivery of a pharmaceutical composition to a patient has a delivery device configured to deliver a dose of the pharmaceutical composition to the patient and a notification device in communication with the delivery device. The notification device is configured to communicate information about a status of at least one property of the delivery device. The delivery device is a wearable automatic injector configured to be worn on the patient's skin. A delivery device of the present disclosure allows a user or patient to view the status of a container. For example, a delivery device of the present disclosure provides a simple and effective visual means of displaying fill confirmation and delivery confirmation.
Resumen de: EP4825333A2
A dental overlay device includes a base (1013), connecting strut (1018), and veneer holder (1019). The base has a curvature in the form of an arch of a patient and defines a curved axis. The connecting strut has a first end attached to the base and a second end and extends in a generally orthogonal direction to the curved axis. The veneer holder has first and second ends and extends in a transverse direction to the direction the connecting strut extends. The second end of the connecting strut is attached to the veneer holder. A dental overlay device and veneer combination includes a first veneer and a second veneer prepared for mounting onto the plurality of teeth. Floss is configured for passing between the first veneer and the second veneer when the dental overlay device is mounted onto the plurality of teeth.
Resumen de: WO2025124483A1
Provided is an oral drug dosage form configured to be used for targeted drug delivery at a desired gastrointestinal location, methods of design and use related to the oral drug dosage form.
Resumen de: CN122939097A
本发明公开了一种面向足底压力调控鞋垫及其逆向设计方法，涉及足部矫形辅具与增材制造技术领域。所述方法先根据增材制造设备参数与孔隙连通约束确定可制造偏移参数区间，以及对应的可实现等效模量区间，将制造约束前置；再采集使用者足底压力云图并预处理得到归一化压力场，按压力越高模量越低的逆向映射构建目标模量场，反解为三周期极小曲面薄壁结构的偏移参数场，进而生成沿鞋垫连续变化的梯度多孔薄壁结构，并按单道沉积线宽生成可变线宽逐层打印路径。本发明解决了现有鞋垫个体针对性不足、梯度薄壁结构可制造性差的问题，且能够在单一材料下实现高压区域泄力、支撑区域稳定支撑的个体化连续梯度鞋垫，可制造性好。
Resumen de: CN122937296A
本发明公开了一种支架‑屏障膜一体化引导骨再生结构及其制备方法，属于生物医用材料及口腔颌面外科骨再生医疗器械技术领域。本发明提供的支架‑屏障膜一体化引导骨再生结构，基于3D打印技术，且主体材料包含光交联水凝胶(如甲基丙烯酰化明胶）、海藻酸盐及介孔生物活性玻璃。为解决临床牙槽骨增量中成骨空间丧失（引导骨再生支架的移位、塌陷）和软组织提前长入的两大难题提供一种全新、更有效的一体化解决方案，将目前临床中最常应用的两步法（骨替代支架+屏障膜）合为一步，这种设计有望简化手术步骤，降低医师术中操作难度，具备重要临床转化前景。
Resumen de: CN122941025A
本发明公开了一种用于3D打印的液态金属‑明胶基热响应导电复合水凝胶及其制备方法和应用，本发明以甲基丙烯酰化明胶、SiO2包覆液态金属分散液、没食子酸、聚乙二醇二丙烯酸酯和引发剂为原料，利用甲基丙烯酰化明胶的温度敏感性和镓铟合金的导电性，制备得到具有热响应的导电复合水凝胶，再结合聚合的没食子酸增强了粘附性能，纳米SiO2包覆液态金属提高分散性，制备的水凝胶兼具热响应性能、皮肤界面粘附性能和导电性能，且具有优异的3D打印流变性能，能够长期、稳定地监测多种电生理信号，解决了现有导电复合水凝胶灵敏度不足、皮肤贴合性差及信号采集稳定性欠佳等问题。
Resumen de: CA3112338A1
Embodiments relate to an aligner breakage solution. A method includes obtaining a digital design of a polymeric aligner for a dental arch of a patient. The polymeric aligner is shaped to apply forces to teeth of the dental arch. The method also includes performing an analysis on the digital design of the polymeric aligner using at least one of a) a trained machine learning model, b) a numerical simulation, c) a geometry evaluator or d) a rules engine. The method may also include determining, based on the analysis, whether the digital design of the polymeric aligner includes probable points of damage, wherein for a probable point of damage there is a threshold probability that breakage, deformation, or warpage will occur. The method may also include, responsive to determining that the digital design of the polymeric aligner comprises probable points of damage, performing corrective actions based on the probable points of damage.
Resumen de: CN122937233A
本发明提出了一种脂质溶致液晶载药组合物及其制备方法与在口服递送中的应用，属于药物递送系统与功能性食品技术领域。本发明的组合物包括含单油酸甘油酯与亚油酸组成的油相、含Pluronic F127和KCl、烟酰胺的水相。本发明利用挤出式3D打印喷嘴内的高剪切流场诱导液晶畴由随机多畴结构转变为取向有序结构，实现对纳米水通道曲率与连通性的主动编程。该载体利用胃肠道天然pH梯度作为内源性触发信号，在胃部酸性环境中保持结构稳定实现缓释，在肠道中性环境中发生相变促进药物释放，同时通过再分散形成纳米胶体增强细胞吸收。本发明突破了传统液晶被动自组装模式的局限，为水溶性营养素的口服精准递送提供了绿色高效的新策略。
Resumen de: WO2025231436A1
An expandable prosthetic device used as a prosthesis during surgery. The expandable prosthetic device is configured for use in the extremities of a body such as, but not limited to, use in the expansion of the lateral or medial column of a foot. The expandable prosthetic device includes a drive block, a linkage block, a drive screw, a first endplate, a second endplate, and first and sets of linkages. Rotation of the drive screw causes movement of the linkage block relative to the drive block and/or movement of the first endplate relative to the second endplate.
Resumen de: US12765969B1
The present invention is directed to a dental retainer. The dental retainer may comprise a retainer wire, a left bracket (or receptacle) and a right bracket (or receptacle) placed on the lower lingual side of the lower incisor teeth. The dental wire may be adapted to hold the lower teeth of a patient in place after the patient has undergone a procedure to realign the teeth. The lingual side if the left bracket may be adapted to couple to the lingual side of the bracket on lower right cuspid. The retainer wire may detachably couple to the left bracket and the right bracket such that the retainer wire is adapted to press against the lingual side of the lower incisors to retain the lower incisors in position. The retainer wire may be adapted to be removed and replaced in to clean the teeth, further adapt the wire, and be replaced for continued use. The retainer wire may be manufactured using a 3D printer.
Resumen de: JP2026168705A
【課題】複数の薬包の各々の薬品を効率よく鑑査する。【解決手段】薬品鑑査システムは、処方に基づいて薬品が分包された複数薬包の各々を撮影した薬包画像を取得する画像取得部と、前記複数薬包のそれぞれの薬包画像に基づき、前記複数薬包それぞれの薬品が処方通りか否かを鑑査する鑑査部と、前記鑑査部の鑑査結果を出力する出力部と、前記複数薬包の薬包画像から、指定された薬品を含む薬包画像を抽出して表示する薬品抽出表示部と、を備える。【選択図】図１
Resumen de: CN122912061A
本发明涉及医药技术领域，具体涉及一种黄精碳纳米粒及其制备方法与应用。本发明成功构建了一种黄精碳纳米粒的制备方法，采用本发明方法制备得到的黄精碳纳米粒具备优异的体外抗氧化能力、生物安全性以及明确的保肝活性，可通过“代谢调节‑抗氧化防御‑线粒体保护”多途径协同实现保肝作用，显著预防酒精诱导的肝细胞损伤。本发明为解析黄精炮制过程中纳米活性物质的生成规律、开展中药炮制纳米机制研究提供了实验与理论支撑，并为开发新型低毒、高效保肝中药纳米制剂提供了全新研发思路。
Resumen de: CN122914520A
一种用于声带原位生物打印的温敏型双腔混胶管套件，包括管体组件、微流控混胶组件、温控传感组件及对接底座组件，管体组件包括外保护管和内设隔离隔板的内隔管，形成独立的第一、第二输液腔，实现多组分反应性流体的物理隔离输送；微流控混胶组件的混合通道内设有交错排布的阻流微凸起结构，以实现流体的高效受迫混合；温控传感组件包括收容于管体环形夹层内的柔性加热膜和嵌设于汇流腔侧壁的微型温度传感器，其通过对接底座组件与外部设备连接，本发明专利有效解决了打印过程易堵塞、混合不均及温控缺失等问题，显著提升了原位生物打印的质量与稳定性。
Resumen de: CN122913518A
本发明公开了一种增材制造医用多孔Ti‑6Al‑4V合金材料的制造方法，包括：设计具有预定孔隙率的多孔点阵三维模型，其中，多孔点阵三维模型由多个周期性阵列排布的多孔单胞所形成；选用Ti‑6Al‑4V合金粉末，通过选区激光熔化技术成形步骤S1的多孔点阵三维模型，使支柱内部原位形成连通的微米级孔隙网络，得到成型支架；对成型支架进行微弧氧化处理，在包括所述微米级孔隙网络内壁的所有表面构建纳米级粗糙织构。上述制备方法通过设计的多孔点阵三维模型，依托单胞内部的拓扑镂空设计，在点阵单胞、宏观点阵体系中构建全维度贯通的连通孔隙网络，再结合微弧氧化处理，全表面实现生物活性强化，大幅提升成骨细胞的黏附与增殖效率。
Resumen de: CN122918305A
本发明公开了一种基于3D打印技术的钴铬矫治器应力消除装置，涉及齿科矫形器后处理领域，包括：固定在真空烧结炉顶部的吊装滑轨，且吊装滑轨位于真空烧结炉内腔中心线的正上方，吊装滑轨的外表面滑动套装有滑轨套块，且滑轨套块的底部固定设置有型材条，本发明中通过吊装滑轨和滑轨套块的作用能够对承托单元的位置进行调整，每次位置调整完成后可在制动单元的作用下，对滑轨套块和吊装滑轨的位置进行锁定，避免两个托板随意滑移，升降部件的作用可以辅助工作人员将基板以及上方的矫治器产品取放在真空烧结炉内，即无需工作人员佩戴劳动手套在炉腔内拿取，从而避免工作人员对退火后的基板拾取时，出现烫伤状况。
Resumen de: CN122917247A
本发明公开了一种抗菌光固化树脂及其制备方法与应用，属于高分子材料及3D打印技术领域。由如下重量份的组分组成：UDMA，41~50份；TEGDMA，8~10份；Bis‑EMA，8~10份；IBOA，16~20份；LMA，8~10份；BTO NPs，3~15份；光引发剂，0.5~2份。UDMA为骨架，添加的BTO NPs均匀分散于网络中，打印成形后无需表面涂层，在微机械刺激下产生活性氧物种（ROS），实现半靶向抑菌。
Resumen de: US2023251087A1
0000 An extendible or adjustable length level is provided. The level includes a locking mechanism allowing the user to fix the level at a selected or desired level. The locking system allows the user to lock the level at the desired length and provides more effective and robust locking than conventional expanding levels. In some embodiments, the locking mechanism is designed such that translational movement of the user-actuated control (as opposed to rotational motion) is used to move the locking mechanism into the locked position.
Resumen de: CN122912177A
本发明公开了一种基于牙骨质微结构的仿生基台及其制备方法与应用，属于种植牙技术领域。本发明根据种植牙基台的三维模型，通过喷墨打印工艺制成的仿生基台具有仿生表面，所述仿生表面分布的微孔结构能够具有接触引导效应，显著促进周围结缔组织中胶原纤维以垂直或大角度倾斜方式嵌入仿生表面的微孔；所述仿生基台具有优异的软组织封闭性能，能够在细胞水平和组织水平上增强基台‑软组织界面的结合强度和密封性，形成更接近天然牙周组织的防御屏障；所述仿生基台具有特定的形貌参数，能够提升仿生表面的生物活性，能够有效促进人牙龈成纤维细胞的粘附、增殖、铺展及功能表达。
Resumen de: CN122912188A
本发明提供了一种用于修复软骨缺损的3D打印复合生物墨水及其制备方法和应用，所述复合生物墨水包括以下质量分数的组分：生物高分子材料25~30 wt.%、脱细胞基质10~30 wt.%、聚环氧乙烷10 wt.%，余量为超纯水；所述复合生物墨水还包括交联剂，所述交联剂浓度为0.00125 g/ml，所述交联剂为苯基‑2,4,6‑三甲基苯甲酰基次膦酸锂。采用本发明提供的用于修复软骨缺损的3D打印复合生物墨水制备的软骨组织工程支架，具有良好的生物学功能，能够有效促进软骨损伤部位的结构重建和功能恢复。
Resumen de: WO2025072538A1
Methods and systems for exposing a patient to a neutron beam according to a treatment plan for treating a tumor in the patient using boron neutron capture therapy (NCT) are disclosed.
Resumen de: US20260306221A1
Systems, methods, and computer program products for manufacturing orthodontic aligners. A mold is fabricated based on a dentition model representing the dentition of a patient at a stage of orthodontic treatment. The mold is scanned to generate a pre-use mold model representing an outer surface of the mold. The pre-use mold model is compared to one or both of a dentition model and an aligner model to identify any differences. If a difference is identified between the pre-use mold model and the detention model exceeding a threshold, the mold is failed. If no differences are found exceeding the threshold, the mold is passed. If used, the aligner model is generated by scanning a workpiece fabricated using the mold. If a difference is identified between the pre-use mold model and the aligner model exceeding a threshold, the workpiece is failed. If no differences are found exceeding the threshold, the workpiece is passed.
Nº publicación: JP2026169206A 16/10/2026
Solicitante:
バイオセンス・ウエブスター・（イスラエル）・リミテッド
Resumen de: EP4819158A1
0001 A system trains a set of machine-learning models to predict which atrial fibrillation patients would respond to which treatments using ablation lines. The models identify an ablation line treatment for a patient based on atrial fibrillation-related features associated with the patient. The models estimate reconnection probabilities for ablation sites associated with at least one ablation line treatment. The models identify patient atrial fibrillation predictors associated with the patient, based on demographics and heart component dimension parameters associated with the patient, and use the at least one ablation line treatment, reconnection probabilities, patient atrial fibrillation predictors, and patient demographics to predict whether the patient would not respond to pulmonary vein isolation only treatment. In response to a prediction that the patient would not respond to pulmonary vein isolation only treatment, the system enables a healthcare provider to provide the at least one ablation line treatment for the patient.
BOPI
Sede Electrónica
