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Bioimpresión 3d

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LastUpdate Última actualización 11/07/2025 [08:20:00]
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钛合金粉末材料、钛合金及其制备方法、应用

NºPublicación:  CN120133517A 13/06/2025
Solicitante: 
香港理工大学深圳大学科能三维技术(医疗)有限公司
CN_120133517_PA

Resumen de: CN120133517A

本申请属于合金材料技术领域,尤其涉及钛合金粉末材料、钛合金及其制备方法、应用。该钛合金粉末材料包括纳米Fe颗粒、纳米TiO2颗粒和Ti颗粒,其中纳米Fe颗粒、纳米TiO2颗粒分布在Ti颗粒的表面。该钛合金粉末材料中的Fe和TiO2以纳米颗粒的形式存在,并分布在Ti颗粒的表面,这样的分布有利于提高Fe元素和O元素的分布均匀性,缓解元素偏析形成有害力学性能的β‑fleck问题,进而改善钛合金的力学性能均匀性。

一种极小曲面结构多孔钽的制备方法及其医疗应用

NºPublicación:  CN120133543A 13/06/2025
Solicitante: 
深圳大洲医学科技有限公司
CN_120133543_PA

Resumen de: CN120133543A

本发明涉及一种基于极小曲面结构的多孔钽材料的制备方法及其医疗应用,尤其应用于椎间融合器、人工椎体、髋关节臼杯、关节填充块和牙种植体等医疗植入物。材料为纯钽或含钽合金(如钽钛、钽铌、钽锆、钽钛铌锆,钽含量大于1%),采用增材制造技术构建,孔隙率30~90%,其相比于桁架孔道结构(如菱形十二面体)无明显的应力集中点,在强度、模量、抗疲劳性能等方面均有显著提升,特别适合用于大面积和承重骨缺损的结构和功能重建。

骨性Ⅱ类错颌畸形正颌手术辅助器械组件及其制备方法

NºPublicación:  CN120131133A 13/06/2025
Solicitante: 
广州医科大学附属口腔医院(广州医科大学羊城医院)
CN_120131133_PA

Resumen de: CN120131133A

本发明提供一种骨性Ⅱ类错颌畸形正颌手术辅助器械组件及其制备方法,截骨辅助部件包括固定支持夹板与第一定位导板,第一定位导板中设有截骨定位槽、钛钉定位孔与髁突位置指示孔,固定支持夹板与第一定位导板通过第一连接杆保持固定姿态连接;定位辅助部件包括咬合夹板、髁突定位板与第二定位导板,髁突定位板贴合于患者的近心段下颌支表面,与患者的下颌支固定连接,第二定位导板中设有钛板定位框,咬合夹板分别与髁突定位板及第二定位导板通过第二连接杆及第三连接杆保持固定姿态连接。通过本发明,可建立与患者颌骨精准适配的截骨辅助部件与定位辅助部件,实现对颌骨的定位与固定功能。

一种3D打印超材料压电型骨缺损修复支架及其制备方法

NºPublicación:  CN120132062A 13/06/2025
Solicitante: 
大连理工大学附属中心医院(大连市中心医院)
CN_120132062_PA

Resumen de: CN120132062A

本发明属于生物医学工程与增材制造交叉领域,具体涉及一种3D打印超材料压电型骨缺损修复支架,所述支架的孔隙结构由数学表达式定义的Gyroid、SchwarzP和Diamond三种极小曲面单元复合构成;所述支架的孔隙率为30%‑70%,孔径范围为0.1‑1mm;所述支架的材料为由聚偏氟乙烯、聚乳酸及钛酸钡组成的压电复合材料,所述压电复合材料按质量百分比如下:聚偏氟乙烯(PVDF)30%‑55%,聚乳酸(PLA)20%‑45%,钛酸钡(BaTiO3)10%‑25%,且各组分的质量百分比之和为100%。该发明通过多材料3D打印技术实现宏观结构及微观结构的精准调控,具有力学适配性、降解可控性和主动促进骨再生功能,适用于颅颌面、四肢长骨等大段骨缺损修复场景。

一种兼具抗菌与促成骨性能的钛基植入物及其制备方法和应用

NºPublicación:  CN120132042A 13/06/2025
Solicitante: 
山东大学
CN_120132042_PA

Resumen de: CN120132042A

本发明公开了一种兼具抗菌与促成骨性能的钛基植入物及其制备方法和应用,属于生物医用材料与生物医学交叉技术领域。本发明以选区激光熔化多孔钛合金为基体,利用微弧氧化和水热处理,在其表面构建兼顾抗菌及促成骨的多功能复合涂层;并通过掺杂功能性元素对涂层的微观结构及生物学性能进行调控,从而对涂层的抗菌性能和促成骨性能进行优化。

化粧組成物

NºPublicación:  JP2025089341A 12/06/2025
Solicitante: 
花王株式会社
JP_2025089341_A

Resumen de: US2023210752A1

A cosmetic composition including a solvent A, a solvent B, a polymer C and a colorant. The solvent A is at least one selected from the group consisting of ethanol, n-propanol and isopropanol. A boiling point of the solvent B is 150° C. or higher. The solvent B is compatible with the solvent A, and the polymer C is soluble in the solvent A and insoluble in the solvent B. A content of the solvent B is 5% by mass or more and 40% by mass or less, and a ratio by mass of a content of the solvent A to a content of the solvent B solvent A/solvent B in the cosmetic composition is 1 or more and 15 or less.

セラミック分散体またはセラミックゲルを製造するための化学物質のセット

NºPublicación:  JP2025518130A 12/06/2025
Solicitante: 
セラミストワンゲーエムベーハー
JP_2025518130_PA

Resumen de: CN119278190A

The invention relates to a chemical combination for producing a ceramic dispersion or a ceramic gel, to a method for producing a ceramic molded part, and to a ceramic molded part produced by the method.

BONE REPAIR MATERIAL, PREPARATION METHOD THEREFOR, AND USE THEREOF

NºPublicación:  WO2025118246A1 12/06/2025
Solicitante: 
SHENZHEN INSTITUTES OF ADVANCED TECH [CN]
SHENZHEN HEALTHEMES BIOTECHNOLOGY CO LTD [CN]
\u6DF1\u5733\u5148\u8FDB\u6280\u672F\u7814\u7A76\u9662,
\u6DF1\u5733\u5E02\u4E2D\u79D1\u6D77\u4E16\u5FA1\u751F\u7269\u79D1\u6280\u6709\u9650\u516C\u53F8

Resumen de: WO2025118246A1

Provided are a bone repair material, a preparation method therefor, and use thereof. The bone repair material is prepared by printing with a material slurry by means of a photocuring 3D printing method and then sintering. The material slurry comprises the following components: 55-65% by mass of bioactive glass, 30-40% by mass of photosensitive resin, 1-5% by mass of a dispersing agent, and 0.1-1% by mass of a photoinitiator. The bone repair material has excellent biocompatibility and relatively high porosity, with the hemolysis rate lower than 5% and the cytotoxicity less than 30%. In addition, the bone repair material has relatively good morphology and relatively superior mechanical properties, and thus can be used as a bone repair scaffold material.

DROPLET DELIVERY DEVICE WITH FILTERING

NºPublicación:  WO2025122635A1 12/06/2025
Solicitante: 
PNEUMA RESPIRATORY INC [US]
PNEUMA RESPIRATORY, INC
WO_2025122635_A1

Resumen de: WO2025122635A1

An aerosol delivery device including a liquid supply, an electronically actuated droplet ejector in fluid communication with the liquid supply, and filter media or inertial filter points between the ejector and a droplets outlet to reduce the droplet size distribution of ejected droplets to smaller droplets exiting the droplets outlet.

HYDROGEL-EXTRACELLLAR MATRIX GRANULAR COMPOSITES WITH VISCOUS INTERSTITIUM

NºPublicación:  WO2025122495A1 12/06/2025
Solicitante: 
CZ BIOHUB SF LLC [US]
THE REGENTS OF THE UNIV OF CALIFORNIA [US]
CZ BIOHUB SF, LLC,
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Resumen de: WO2025122495A1

Composite matrix materials including a plurality of microgel particles having a mean particle size in a range of about 1 μm to about 100 μpm, and an interstitial matrix, where the composite matrix is characterized by reversible yield-stress behavior at 4°C; methods of preparation of the composite matrix materials; and methods of preparing organoids from the composite matrix materials are disclosed.

PATIENT SPECIFIC SURGICAL GUIDE LOCATOR AND MOUNT

NºPublicación:  US2025186062A1 12/06/2025
Solicitante: 
MICROPORT ORTHOPEDICS HOLDINGS INC [NL]
Microport Orthopedics Holdings, Inc
US_2025186062_A1

Resumen de: US2025186062A1

A resection guide locator includes a bone engagement portion with surfaces that are complementary to the surface topographies of a bone to be resected during surgery. A housing includes a socket defined by a resilient annular wall that is sized and arranged so to accept a resection guide by press-fit to thereby position and hold the resection guide within the socket. The resection guide is maintained in a predetermined, preferred position while the surfaces are releasably locked in position on the bone. A method is disclosed for forming and using the resection guide locator.

THREE-DIMENSIONAL CELL-LADEN BIOINK SCAFFOLDS AND METHODS OF MAKING THE SAME UNDER CRYOGENIC CONDITIONS FOR TISSUE ENGINEERING

NºPublicación:  US2025188298A1 12/06/2025
Solicitante: 
UNIV OF MARYLAND BALTIMORE [US]
University of Maryland, Baltimore
US_2025188298_A1

Resumen de: US2025188298A1

The present invention provides three-dimensional, cell-laden bioink scaffolds, methods of making and using the same.

PRINTING MECHANISM FOR MEDICAL MONITORING DEVICE AND MEDICAL MONITORING DEVICE

NºPublicación:  US2025187357A1 12/06/2025
Solicitante: 
KONINKLIJKE PHILIPS N V [NL]
KONINKLIJKE PHILIPS N.V
US_2025187357_A1

Resumen de: US2025187357A1

The present invention provides a printing mechanism for a medical monitoring device and a medical monitoring device. The printing mechanism comprises a support plate, a movable frame assembly disposed movably on the support plate. the movable frame assembly comprising a frame, and a print paper drawer for holding the print papers, the print paper drawer being mounted on the frame to move along with the movable frame assembly. The printing mechanism further comprises at least one set of spaced sleeves provided on a top surface of a body of the support plate in a movement direction of the movable frame assembly. and a guide rod passing through holes defined by each set of the spaced sleeves and secured to a bottom of the frame at two ends. the guide rod guiding the movable frame assembly and moving along with the movable frame assembly, wherein a damping bracket is provided between adjacent sleeves of each set of the spaced sleeves, the damping bracket contacts the guide rod and exerts an upward force onto the guide rod perpendicularly to a movement direction of the guide rod. The printing mechanism for the medical monitoring device according to the present invention may ensure that the print paper drawer is positioned with high accuracy and is opened and closed smoothly when the printing mechanism operates in the horizontally arranged state or the vertically hung state.

Photocurable Materials for the Production of Dental Prostheses and Devices

NºPublicación:  US2025187262A1 12/06/2025
Solicitante: 
PAC DENT INC [US]
Pac-Dent, Inc
US_2025187262_A1

Resumen de: US2025187262A1

A resin based material whose composition includes a light-curable mixture of monomers of no more than 35 wt. % of an ethoxylated difunctional bisphenol A dimethacrylate; of no more than 10 wt. % of a methacrylate monomer; of no more than 10 wt. % of a difunctional urethane acrylate; of no more than 0.1 wt. % of an optical brightener; of no more than 5 wt. % of silica particles having methacrylate functionalization layers and having an average particle size of less than about 200 nm; of having more than 40 wt. % of an inert glass; of no more than 15 wt. % of a heavy metal oxide; of no more than 2.5 wt. % of an ultraviolet/visible (UV/Vis) light-photo-polymerization initiator; a colorant; and a stabilizer.

System and Methods for Preparation of Adipose-Derived Stem Cells

NºPublicación:  US2025186502A1 12/06/2025
Solicitante: 
JOINTECHLABS INC [US]
Jointechlabs, Inc
US_2025186502_A1

Resumen de: US2025186502A1

A device that allows for either fat graft preparation or cell fraction harvest is disclosed. The device includes a first centrifuge tube configured to receive and process a biological substance, the first centrifuge tube comprising an upper cylindrical portion and a lower conical portion, a sterile tissue inlet fitting, at least one sterile processing fluid inlet fitting, a sterile suction fitting, and at least one sterile extraction port connected to a first extraction tube. The first centrifuge tube further includes an internal space including a screen being positioned therein, the screen being configured to divide the internal space in half, and a filter positioned therein, the filter being positioned below the screen in the lower conical portion of the first centrifuge tube. The device may further include a second centrifuge tube configured to receive and further process the biological substance from the first centrifuge tube. The second centrifuge tube has at least one sterile fitting, wherein the second centrifuge tube is releasably connected via the at least one sterile fitting to one of the at least one sterile extraction ports of the first centrifuge tube.

SHAPE MORPHING HYDROGEL ACTUATORS AND CONSTRUCTS

NºPublicación:  US2025186656A1 12/06/2025
Solicitante: 
CASE WESTERN RESERVE UNIV [US]
Case Western Reserve University
US_2025186656_A1

Resumen de: US2025186656A1

A construct includes a biocompatible polymer-based shape morphing hydrogel or cell condensate that is configured to undergo multiple, reversible, and/or controllable different shape transformations over time via either pre-programmed design or user-controlled environmental condition alterations, wherein the hydrogel is cytocompatible and, upon degradation, produces substantially non-toxic products.

Suprakonstruktion, Zahnprothese und Verfahren zum Herstellen einer Zahnprothese

NºPublicación:  DE102024120715B3 12/06/2025
Solicitante: 
TRI DENTAL IMPLANTS INT AG [CH]
TRI Dental Implants Int. AG
DE_102024120715_PA

Resumen de: DE102024120715B3

Suprakonstruktion (14) für eine Zahnprothese (10), aufweisend einen Zahnkronengrundkörper (24), der mindestens eine künstliche Zahnkrone trägt, einen Positionierkörper (26) mit einer Durchgangsöffnung zur Aufnahme eines Befestigungsmittels (16) zum mittelbaren oder unmittelbaren Befestigen der Suprakonstruktion (14) an einem Zahnimplantat (12), und eine Kopplungseinrichtung, die den Positionierkörper (26) mit dem Zahnkronengrundkörper (24) verliersicher koppelt und dazu eingerichtet ist, eine Relativbewegung des Positionierkörpers (26) relativ zu dem Zahnkronengrundkörper (24) zu ermöglichen.

METHOD FOR MANUFACTURING A REMOVABLE PARTIAL DENTAL PROSTHESIS, AND REMOVABLE PARTIAL DENTAL PROSTHESIS

NºPublicación:  WO2025120283A1 12/06/2025
Solicitante: 
CIRCLE ANATOSCOPE INTUITIVE DESIGN [FR]
CIRCLE ANATOSCOPE INTUITIVE DESIGN
FR_3156030_PA

Resumen de: WO2025120283A1

The invention relates to a method for manufacturing a removable partial dental prosthesis, the method comprising the steps of: a) manufacturing at least one monolithic block comprising an artificial tooth part and an artificial gum part, the monolithic block comprising at least one first joining member; b) manufacturing a frame that is configured to support the monolithic block, the frame comprising at least one second joining member; then c) joining the monolithic block to the frame by interlocking the first joining member with the second joining member to form the removable partial dental prosthesis.

A LENTICULE, METHOD OF PREPARATION AND IMPLEMENTATIONS THEREOF

NºPublicación:  WO2025120669A1 12/06/2025
Solicitante: 
PANDORUM TECH PRIVATE LIMITED [IN]
PANDORUM TECHNOLOGIES PRIVATE LIMITED

Resumen de: WO2025120669A1

The present disclosure provides a three-dimensional hydrogel prepared using a bioink composition comprising methacrylated hyaluronic acid, methacrylated gelatin, a photoinitiator and a photoabsorber; and a method for preparing the three- dimensional hydrogel or lenticule. The present disclosure further provides a method of treating corneal tissue repair in a subject in need thereof using the three- dimensional hydrogel or lenticule.

BIODEGRADABLE 3D PRINTED STRUCTURE FOR BONE AUGMENTATION

NºPublicación:  WO2025120338A1 12/06/2025
Solicitante: 
SVEUCILISTE U ZAGREBU FAKULTET KEMIJSKOG INZENJERSTVA I TEHNOLOGIJE [HR]
SVEU\u010CILI\u0160TE U ZAGREBU FAKULTET KEMIJSKOG IN\u017DENJERSTVA I TEHNOLOGIJE

Resumen de: WO2025120338A1

Biodegradable 3D printed structure for bone augmentation (1) comprises an outer structure (100) and an inner structure (200) that are printed from polylactide (PLA), wherein the inner structure (200) is filled with a chitosan and hydroxyapatite gel and the outer structure (100) is coated with a chitosan and hydroxyapatite composite. The outer structure (100) has a tunnel-like shape resembling an elongated projection of the letter "U" rotated 180 degrees in depth. Implants made in the form of a biodegradable 3D-printed structure for bone augmentation as disclosed in the present invention can be adapted to each individual patient and each individual situation, which will optimize the dentist's time required for the procedure and treatment, and will also facilitate the recovery of the patient due to the reduction of the invasiveness of the procedure. This makes the entire procedure faster, simpler, and painless, but also financially acceptable for patients.

METHOD OF MANUFACTURING PROSTHETIC SOCKET INTERFACE

NºPublicación:  US2025190637A1 12/06/2025
Solicitante: 
ALLEY RANDALL D [US]
WILLIAMS III T WALLEY [US]
Alley Randall D,
Williams, III T. Walley
US_2025190637_A1

Resumen de: US2025190637A1

A method of manufacturing an interface for a body part is described. The method includes the step of selecting an inner radial dimension of the interface to have a plurality of compression areas that extend along the long axis of the interface. The method also includes the step of spacing the plurality of compression areas circumferentially around the long axis of the interface to create a compression pattern. The compression pattern is sized and dimensioned to reduce motion of the skeletal structure towards a wall of the interface when the interface is worn on the body part by compressing soft tissue of the body part against the skeletal structure.

プログラム、3次元データ設計装置、3次元データ設計方法および3次元データ設計システム

NºPublicación:  JP2025088292A 11/06/2025
Solicitante: 
株式会社リコー
JP_2025088292_A

Resumen de: JP2025088292A

【課題】歯型の模型の形状に依存せず、レジンが外れにくい義歯(前装冠)の3次元データを生成する。【解決手段】コンピュータに、歯型の3次元データに応じた3次元歯型モデル上で、ビーズ状の構造体を配置する範囲または箇所の指定を受け付ける配置範囲受付部と、前記配置範囲受付部で指定を受け付けた範囲または箇所に基づいて、前記3次元歯型モデル上で前記ビーズ状の構造体を所定間隔にて配置する配置部と、前記配置部によって配置された前記ビーズ状の構造体の3次元データと前記歯型の3次元データとを出力する出力部と、を実現させるためのプログラムである。【選択図】図6

PHARMACEUTICAL FORMULATION PRINTING DEVICE

NºPublicación:  ES3026523T3 11/06/2025
Solicitante: 
QUALICAPS CO LTD
Qualicaps Co., Ltd
JP_WO2018100980_A1

Resumen de: US2019276239A1

Provided is a pharmaceutical formulation transporting device capable of easily ensuring a large exposed area of a solid pharmaceutical formulation during transport. A pharmaceutical formulation transporting device 10 comprises a first pulley 11, a second pulley 12, and a plurality of endless transport belts 13, 14 wound around the first pulley 11 and the second pulley 12, wherein the plurality of transport belts 13, 14 are disposed so as to be capable of holding a solid pharmaceutical formulation between respective first side surfaces.

BIODEGRADABLE 3D PRINTED STRUCTURE FOR BONE AUGMENTATION

NºPublicación:  EP4566637A1 11/06/2025
Solicitante: 
TOPOMATIKA D O O [HR]
TOPOMATIKA d.o.o
EP_4566637_PA

Resumen de: EP4566637A1

Biodegradable 3D printed structure for bone augmentation (1) comprises an outer structure (100) and an inner structure (200) that are printed from polylactide (PLA), wherein the inner structure (200) is filled with a chitosan and hydroxyapatite gel and the outer structure (100) is coated with a chitosan and hydroxyapatite composite. The outer structure (100) has a tunnel-like shape resembling an elongated projection of the letter "U" rotated 180 degrees in depth. Implants made in the form of a biodegradable 3D-printed structure for bone augmentation as disclosed in the present invention can be adapted to each individual patient and each individual situation, which will optimize the dentist's time required for the procedure and treatment, and will also facilitate the recovery of the patient due to the reduction of the invasiveness of the procedure. This makes the entire procedure faster, simpler, and painless, but also financially acceptable for patients.

Dental and skeletal training aid and method for producing same

Nº publicación: GB2636068A 11/06/2025

Solicitante:

MOUSE DESIGN LTD [GB]
Mouse Design Ltd

GB_2636068_PA

Resumen de: GB2636068A

The present invention relates to an artificial tooth 10 or bone formed from a unitary 3D printable material. An artificial tooth comprises an outer enamel-like portion 12 and an inner dentine-like portion (14) having voids therein. The outer layer offers a high resistance to drilling and may be of stereolithography (SLA) resin comprising three parts: Urethane Dimethacrylate (UDMA), Isobornyl Methacrylate (IBMA) and a reinforcing agent, such as glass filler, ceramic powder, carbon or graphene. The dentine layer has foam or sponge-like properties with voids or channels 16 and is of lower resistance to drilling. A pulp layer 18 of e.g., a wax-type material, 3D printing resin, silicone or rubber may be provided to mimic tooth pulp. The printing method may be e.g., a resin-vat stereolithography or a material extrusion method. Simulated bone may be produced in a similar manner. A tooth may be implanted in a phantom head for training purposes.

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