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METHODS TO RAPIDLY ASSESS CHANGES IN MEDICAMENT NEEDS FOR ACCELERATED SHORT-TERM ADAPTIVITY OF AUTOMATED MEDICAMENT DELIVERY SYSTEMS

Resumen de: EP4679441A1

Exemplary embodiments relate to automated medicament delivery (AMD) devices. Exemplary methods and apparatuses allow the AMD to account for the eventual impact of remaining medicament-on-board (MOB) on reduction in glucose concentrations, and do not incorporate the impact of meals on increases in glucose concentrations. This allows the AMD system to estimate the user's final glucose concentration if the impact of both carbohydrate ingestion and existing MOB are fully realized. Consequently, an AMD system can personalize its behaviors to a particular user more rapidly than if the system were to rely simply on previous medicament delivery and glucose histories. This is especially useful when a user begins using an AMD system with an inaccurate or poorly estimated initial value for total daily medicament (TDM) delivery.

MEAL RESPONSE PREDICTION

Resumen de: EP4679440A1

A processor-implemented method comprises obtaining measured glucose values of a person, fitting a physiological model to a portion of the measured glucose values within a time window after a start of a meal to determine meal-specific values of parameters of the physiological model that characterizes the person's glycemic response to the meal, and predicting a future blood glucose level of the person at a first time after the time window using the physiological model and the meal-specific values of the parameters of the physiological model. In one example, an alert or a notification can be sent to a user or an electronic device based on the predicted future blood glucose level of the person.

RESIDUAL CARB ESTIMATION FOR BOLUS CALCULATION

Resumen de: EP4679439A1

A processor-implemented method comprises obtaining measured glucose values of a person, fitting a physiological model to a portion of the measured glucose values within a time window after a start of a meal to determine meal-specific values of parameters of the physiological model that characterizes the person's glycemic response to the meal, estimating an amount of residual glucose or residual carbohydrate of the meal that would not be counteracted by insulin already delivered to the person using the physiological model and the meal-specific values of the parameters of the physiological model, and determining a dose of a correction bolus to be delivered to the person based on the amount of residual glucose or residual carbohydrate of the meal.

A raman probe and apparatus and method for non-invasive in vivo measurement of analyte presence or concentration

Nº publicación: GB2700315A 14/01/2026

Solicitante:

RSP SYSTEMS AS [DK]
RSP Systems A/S

Resumen de: GB2700315A

A non-invasive in vivo measurement by Raman spectroscopy of an analyte (e.g. glucose) present in the skin of a subject (e.g. in the interstitial fluid). A controllable vertical-cavity surface-emitting laser (VCSEL) source 32, spatially separated from a detector 30, irradiates the skin 33 of the subject. The VSCELs selectively change the wavelength of light in using SWEPT methodologies. A bandpass filter receives Raman scattered radiation transmitted from the sample and a processor generates a Raman spectrum from the received Raman scattered radiation. The VCSELs may be distributed around the detector. The light sources 151 may be included in a generally planar probe (e.g. provided on a PCB) integrated with a spectrometer for miniaturisation. The probe may include a slit plate 146 having a slit 148 around which the light sources are arranged. The arrangement may provide spatially offset Raman spectroscopy (SORS). Figs 3&19A