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150
resultados
Última actualización
23/08/2025 [07:16:00]
Resultados 50 a 75 de 150
Resumen de: US12383654B1
An acellular matrix woven material, a preparation method and an application thereof are provided. The acellular matrix woven material is prepared by combining 3D printing with weaving. At the same time, also provided are the acellular matrix woven material prepared by the preparation method and its application in preparing tissue engineering scaffold materials.
Resumen de: WO2024120583A1
The invention relates to a tool for use as a micromanipulator and to a method for producing the tool. The tool consists of a plurality of parts in the form of - a frame (1) which is oriented along a longitudinal axis (L) and which is arranged as a hollow body around an interior, - at least one manipulator element (2) arranged on a first end face (1.1) of the frame (1), and - at least one actuation element (3) which is arranged on a second end face (1.2) opposite the first end face (1.1) and which is mounted slidably and axially movably in the interior of the frame (1), said parts being connected interlockingly and movably to one another by means of necessary connecting and bearing elements, and the tool being entirely generated by additive manufacture, including all the necessary gaps between the parts movably connected to one another. According to the method, the tool with all its parts and with the gaps between the movable parts is manufactured entirely by additive manufacture in one processing operation.
Resumen de: CN120436817A
本申请的实施方式提供一种托槽定位导板及其设计方法和制备方法，其中，托槽定位导板用于将托槽安装在牙齿表面，具体包括第一定位导板，所述第一定位导板具有沿水平方向设置的第一定位部和与第一定位部唇颊/舌腭侧端连接并沿龈颌方向设置的第二定位部，第二定位部包括第一定位滑槽，所述第一定位滑槽具有在近远中方向的第一开口，托槽可通过第一开口进入第一定位滑槽；装配时，托槽颈部沿所述第一定位滑槽滑动并卡持在第一预定位置处，其中，在所述第一预定位置处托槽底板朝向牙齿表面，所述托槽定位导板佩戴在所述对应牙齿上时，所述第一预定位置处满足所述托槽底板与对应牙齿表面具有填充粘接剂的预留间隙。
Resumen de: CN120436842A
本发明关于一种整形外科可植入可指导软骨塑形的3D打印耳支架，涉及3D打印技术领域。包括支架本体，支架本体上设有缺口，支架本体边缘设有边缘突出部，支架本体的一侧设有反求过来的耳廓部；支架本体的下部向上回折形成钩状部。本发明能够实现高精度的耳部重建，为耳部缺损或畸形的患者提供一种创新、安全且效果优异的修复手段。
Resumen de: CN120436978A
本发明涉及3D打印技术技术领域，具体为一种基于3D打印技术的口腔靶向复合凝胶制备方法，包括低温3D打印设备，低温3D打印设备包括双通道低温挤出喷头、五轴联动运动平台和惰性环境舱；双通道低温挤出喷头包括通道一和通道二，通道一包括益生菌微囊和温敏凝胶，温度为4‑10℃，黏度为3×10³mPa·s，通道二包括白桦多肽/茶多酚光交联预聚体，含0.5%LAP光引发剂；五轴联动运动平台：打印精度±10μm，支持舌背曲面贴合，曲率半径≥2mm；惰性环境舱：氧浓度≤0.5%，温度4‑10℃，湿度30‑40%；有益效果：高活性保留与稳定性：通过惰性环境舱（氧浓度≤0.5%）与低温打印（4‑10℃），益生菌存活率提升至打印后98%，6个月储存后仍≥85%；白桦多肽降解率≤3%，显著优于传统工艺。
Resumen de: KR102844656B1
본 발명은, 제작자와 환자의 대면이 어려운 상황에서도 정확한 의지 소켓을 제작할 수 있도록, 사진측량 기반 역설계 기법 및 3D 프린팅 기술을 활용한 의지 소켓 제작 방법을 제안한다. 상기 의지 소켓 제작 방법은 환자의 잔여지를 여러 각도에서 여러 번 촬영하여 사진측량 기술로 3D 디지털 모델을 획득하는 단계; 획득된 3D 디지털 모델을 기반으로 네거티브 몰드를 디자인하여 3D 프린터로 출력하고, 출력된 네거티브 몰드를 이용하여 신체 모형을 제작하는 단계; 제작된 신체 모형을 기반으로 포지티브 석고 몰드를 제작하는 단계; 포지티브 석고 몰드를 사용하여 수지(resin)로 의지 소켓을 진공 성형하는 단계; 및 진공 성형된 의지 소켓에 현가장치를 설치하는 단계를 포함한다.
Resumen de: CN120436725A
本发明公开了一种牙周辅助加速成骨正畸治疗的手术导板及其制作方法，包括：根据全口牙列牙根三维数据在填倒凹后的牙列数据上设计覆盖所有目标牙及其相邻牙齿的牙冠表面的固位结构模型；在颌骨三维数据的颊侧骨面上分别设计与固位结构模型连接的第一定位结构模型和第二定位结构模型；根据全口牙列牙根三维数据在第一定位结构模型上设计线状开口区域，得到骨皮质切开线定位结构模型，并得到骨皮质切开限位导板数据和骨增量限位导板数据；基于骨皮质切开限位导板数据和骨增量限位导板数据分别进行打印，得到骨皮质切开限位导板和骨增量限位导板。本发明能够提高手术区域的定位准确度，降低手术难度。
Resumen de: CN120436861A
本发明公开了一种桡骨远端骨折的3D打印个性化夹板及其制作方法，包括：背侧板、掌侧板、尺侧板和桡侧板，背侧板、掌侧板、尺侧板和桡侧板均为曲面形夹板，曲面的方向与桡骨形状契合；每个夹板的宽度从手腕向手肘方向逐渐增大；每个夹板的两侧均设置边缘减薄结构；每个夹板的上表面相应位置上设有多对加强筋，在每对加强筋上设有绑带限位卡扣，每对加强筋中的两加强筋之间且位于绑带限位卡扣的正下方处设有绑带下陷平台；背侧板对应位置设置有防尺侧压疮凹陷、防背侧碰撞凹陷和第一防桡侧压疮凹陷；掌侧板对应位置设置有防掌侧肌肉压迫切面；桡侧板对应位置设置有第二防桡侧压疮凹陷。本发明针对患者的个体化差异，制作出满足要求的个性化夹板。
Resumen de: CN120437373A
本发明涉及一种仿生软骨膜‑软骨及其一体化的构建方法和应用，涉及复合生物材料领域。包括如下步骤：(1)将功能性分子和聚己内酯在第一溶剂中共混，得到第一混合溶液；将所述第一混合溶液通过静电纺丝技术，构建功能性的取向纳米纤维膜；(2)采用3D打印技术，在所述功能性的取向纳米纤维膜上进行工程软骨的仿生3D打印，得到第一部分待交联的仿生软骨膜‑软骨；(3)重复步骤(2)的步骤，得到第二部分待交联的仿生软骨膜‑软骨；将两部分依次进行对合、交联反应，得到仿生软骨膜‑软骨。本发明实现了软骨膜‑软骨的仿生一体化构建，并增加其力学强度。
Resumen de: WO2025163396A2
A system may include a donor supply sub-system configured to supply donor material to a donor substrate. The system may include a material transfer sub-system comprising a laser configured to illuminate the donor substrate via a transfer beam. The system may include an instrument head of a medical instrument configured to house the donor substrate, wherein upon an illumination of the donor substrate, the donor material is transferred to receiver material in vivo.
Resumen de: AU2023361612A1
The invention relates to nerve conduits for connecting a lesioned nerve end to a target site. In particular, the invention relates to nerve conduits supporting repair of a nerve lesion and motor control and/or reducing risk of the development of a neuroma at the lesioned nerve end. Accordingly, a nerve conduit (10) for connecting a lesioned nerve end (26) to a target site (28) is suggested, comprising an elongate body (12) formed by a wall (22) and comprising a central portion (14) defining an inner cavity (16) and end portions (18, 19) defining a respective opening (20, 20') to the inner cavity (16) and arranged adjacent to the central portion (14) and at longitudinally opposing ends of the elongate body (12). One end portion (18) is configured as an insertion portion configured for inserting a respective nerve end (26). According to the invention, the other end portion is configured as a nerve end outlet portion (19), wherein an outer diameter of the wall defining the outlet portion (19) is larger than an outer diameter of the wall defining the central portion (14).
Resumen de: WO2025166116A1
Disclosed are systems and methods for a computerized framework for automated ceramic inkjet printing in dental restoration manufacturing. The disclosed ceramic inkjet mesh printing for dental restorations combines precision digital control with ceramic materials to create highly accurate and aesthetically pleasing dental prosthetics. The disclosed mechanisms utilize specialized printheads designed to deposit precise amounts of ceramic materials onto dental substrates, enabling the creation of detailed color gradients and natural-looking surfaces that closely mimic natural teeth.
Resumen de: WO2025166097A1
Disclosed are systems and methods of a decision intelligence (DI)-based computerized framework that automatically and/or dynamically implements a color algorithm for performing staining and glazing dental restorations. The framework operates by leveraging determined color variations through AI/ML-based analysis that generate detailed color maps, which can be translated into precise printing instructions controlling the mixture and layering of dental-grade glazing materials. A printing system can employ multiple print heads with varying base colors and opacity levels to create microscopic color gradients and translucency effects matching natural tooth enamel. The disclosed automated processing applies personalized color patterns in microscopically thin layers, ensuring consistent glaze thickness while replicating regional variations across the tooth surface. Such approach eliminates manual glazing variability while achieving superior customization compared to traditional pre-set patterns, resulting in dental restorations that integrate seamlessly with existing teeth.
Resumen de: WO2025165052A1
The present invention relates to a method for activating natural killer cells, comprising a step of providing electrical stimulation to natural killer cells. Specifically, electrical stimulation under predetermined conditions is applied to natural killer cells by applying an electrical stimulation system established through a 3D-printed electrical stimulation device and a function generator. Here, cancer cell-killing ability and calcium ion-mediated mechanisms are analyzed among induced intracellular effects. In addition, with respect to the natural killer cells produced according to the present invention, a method capable of enhancing the efficacy of a cell therapeutic agent without introducing genetic modification is presented, and the cells can be used to study the correlation between the cancer cell-killing ability and the intracellular calcium ion levels of electrically stimulated natural killer cells.
Resumen de: WO2025164130A1
Provided are: a curable composition for three-dimensional stereolithography, which contains 100 parts by mass of a polymerizable monomer component (A), 40-400 parts by mass of an inorganic filler (B), 0.01-5 parts by mass of a photoinitiator (C), and 0.01-2.5 parts by mass of an activation light absorber (D), and in which 10-90 mass% of the inorganic filler (B) is contained as an organic-inorganic composite filler (E), the value of light scattering index Sc serving as an index of the proportion of light scattered laterally when being irradiated with activation light is 10% or less, and the rate of transmission for activation light in a state prior to being optically cured is 1-50%; and a method for producing the curable composition for three-dimensional stereolithography. The present invention also provides a method for producing a three-dimensional stereolithographic product and a method for producing a dental restoration article, in both of which said curable composition for three-dimensional stereolithography is used.
Resumen de: WO2025163465A1
The present invention provides a method and system for fabricating complex human tissues by integrating bio-electrospraying, cell electrospinning merged with 3D multi material microfluidic bioprinting, and future additions of magnetic and acoustic levitation technologies. The fabricated tissues serve as an alternative to animal testing in drug discovery processes, aiding in the prediction of human physiological responses to various drug compounds.
Resumen de: AU2024212880A1
An apparatus comprises a soft robotic arm and a three-dimensional (3D) bioprinter. The soft robotic arm has actuators for controlling movements of a distal end of the soft robotic arm. The 3D bioprinter is attached to the distal end of the soft robotic arm, and has a print nozzle and soft microtubule artificial muscles (SMAMs) for controlling movements of the print nozzle.
Resumen de: US2025248828A1
The Invention refers to a method for manufacturing a new prosthesis for a lower limb, the method comprising the following steps:a) Providing 3D-data of a prior inner surface of a prior socket and of ist position and its orientation relative to a component adapter, —b) Creating a 3D model of a prosthetic socket with an attachment area for a socket adapter, wherein the prosthetic socket has an inner surface based on the scanned prior inner surface and an outer surface, —c) Determining information about an orientation transmitter, —d) Manufacturing of the prosthetic socket based on the 3D model and providing the orientation transmitter based on the information, —e) Directly or indirectly connecting the manufactured socket to a component adapter by means of the orientation transmitter so that the position and orientation of the inner surface of the prosthetic socket relative to the position and orientation of the component adapter corresponds to the position and orientation of the prior inner surface of the prior socket to the component adapter.
Resumen de: US2025248902A1
The present invention relates to a curable composition for dental purposes. The invention is characterized in that the composition comprises core-shell impact modifiers and 0.1 to 10 wt. % of a binder based on long-chain mono-functional (meth)acrylic acid esters, wherein the ester group has a carbon chain with at least 3 carbon atoms. The invention also relates to the use of the composition as a dental material or a dental auxiliary material, to a dental product made of the composition, and to a method for producing the dental product.
Resumen de: US2025250522A1
A device for modelling physiological and pathophysiological states of the brain is provided. The device comprises a hydrogel with micropattern channels having a length, width and depth. The micropattern channels comprise cells selected from the group consisting of neurons, astrocytes, microglia, oligodendrocytes, neuronal organoids, cancer cells, cancer spheroids, brain tumoral cells and combinations thereof.
Resumen de: US2025252697A1
A method for fabricating a custom headwear for a subject is described. The method comprises generating a three-dimensional head data file for the subject and determining contour lines on the head; automatically generating a headwear data file. The method yet further comprises utilizing the headwear data file to generate a shape for a desired headwear, the shape having an interior configured to restrain growth of the head in first predetermined areas. Still further, the method comprises generating contour lines for the custom headwear.
Resumen de: CN120051272A
The present invention relates to a process for preparing a solid pharmaceutical administration form comprising an amorphous solid dispersion using a 3D printing process. The process is a printing process which allows the production of solid administration forms of a solid drug comprising an amorphous solid dispersion in a simple and flexible manner and makes it possible to obtain rapidly disintegrating dosage forms with high drug loading.
Resumen de: CN119789957A
The invention relates to a novel silicone foam obtained from a foamable, crosslinkable silicone composition, the invention relates to a composition comprising an organopolysiloxane having at least two silicon-bonded alkenyl groups per molecule, an organosilicon-containing compound having at least two and preferably at least three silicon-bonded hydrogen atoms per molecule, a hydrosilylation catalyst, at least one porogen as water, hydrogel or aqueous silicone emulsion, and at least one surfactant, at least one chemical blowing agent; and a linear polydimethylsiloxane.
Resumen de: WO2025165300A1
There is provided material for preventing or reducing scar formation during wound healing, the material comprising: (i) a base poly(lactic-co-glycolic acid) (PLGA); and (ii) a bioactive poly(lactic-co-glycolic acid) (PLGA) copolymer, wherein at least part of the material is in the form of a plurality of protrusions extending from a surface. Also provided are a medical device comprising said material, medical uses of said material, and a method of preparing said material.
Nº publicación: WO2025166254A1 07/08/2025
Solicitante:
ZIMA INT INC D/B/A DANDY [US]
ZIMA INTERNATIONAL, INC. D/B/A DANDY
Resumen de: WO2025166254A1
A method for manufacturing a ceramic inkjet ink for printing on a dental material substrate includes processing solid particle components to a particle size from 0.8 to 1 μm, at a particle size distribution of D98 and adding an effective amount of additives to the solid particle components to produce the ink capable of being dispensed from an inkjet printhead onto a surface of a 3-dimensional dental material substrate having an irregular shape and uneven surfaces, while the 3-dimensional dental material substrate is simultaneously translated and rotated under the inkjet printhead.
BOPI
Sede Electrónica
