Alerta

CONTINUOUS GLUCOSE MONITOR COMMUNICATION WITH MULTIPLE DISPLAY DEVICES

Resumen de: US20260104835A1

0000 A continuous glucose monitor for wirelessly transmitting data relating to glucose value to a plurality of displays is disclosed, as well as systems and methods for limiting the number of display devices that can connect to a continuous glucose transmitter. In addition, security, including hashing techniques and a changing application key, can be used to provide secure communications between the continuous glucose transmitter and the displays. Also provided is a continuous glucose monitor and techniques for authenticating multiple displays, providing secure data transmissions to multiple displays, and coordinating the interaction of commands and data updates between multiple displays.

COATING FOR METAL ALLOY

Resumen de: US20260103781A1

0000 A metal alloy that includes an enhancement coating material. The metal alloy includes rhenium and one or more additives. The enhancement coating is at least partially applied to the metal alloy by a physical vapor deposition (PVD) process, a chemical vapor deposition (CVD) process, an atomic layer deposition (ALD) process, a plasma-enhanced chemical vapor deposition (PE-CVD) process, ion implantation, direct energy deposition (DED), and/or thermal spray techniques like plasma arc spraying, flame spraying, high velocity oxy fuel spraying (HVOF). The enhancement coating is formed of a) 35-95 wt. % zirconium and wherein said enhancement coating includes ZrN, ZrNC, ZrOC or a combination of ZrN and ZrO2, b) 20-85 wt. % titanium and one or more of carbon, nitrogen, oxygen, rhenium, and silicon, c) 40-85 wt. % chromium and one or more of carbon, nitrogen, oxygen, rhenium, and silicon, or d) at least 60 wt. % carbon.

HEART RHYTHM DETERMINATION USING MACHINE LEARNING

Resumen de: US20260102139A1

0000 Circuitless heart rhythm determination can include capturing a video clip of one or more image frames of a target organ through an ultrasound imaging device and submitting the frames to a classifier that has been trained with an annotated set of images, each of a corresponding heart muscle captured at a specified phase of a heart rhythm with a ground truth indication of the specified phase of the heart rhythm drawn from a separately recorded cycle graph of an electrical signal measured over time for the corresponding heart muscle. In response to the submission, a classification can be received of different portions of the submitted frames according to corresponding phases of the heart rhythm. Finally, a contemporaneous phase of the heart rhythm can be determined in the device without sensing electrical signals by way of a closed-loop sensor circuit affixed proximately to the target heart muscle.

SLIDING ELEMENT, METHOD FOR PRODUCING THE SLIDING ELEMENT AND USE OF THE SLIDING ELEMENT

Resumen de: WO2026076477A1

The invention relates to a sliding element (1), in particular for medical components for use in implantology, comprising a substrate (3) and a biomaterial (2) applied to the substrate (3), which biomaterial provides a sliding layer (1a) on its side facing away from the substrate (3), wherein the substrate (3) has multiple cavities (7) on a connection surface (4) facing the biomaterial (2), wherein the cavities (7) are open in the direction of the sliding layer (1a) and at least 50% of the cavities (7) have an undercut (7a) in the direction of the interior of the substrate (3), wherein the substrate (3), in a first profile depth (a) of at least 0.6 μm, has a round-ridged roughness profile with an areal roughness characteristic Sa of less than 0.05 μm, wherein the substrate (3) has the multiple cavities (7) between the first profile depth (a) and a second profile depth (b), and wherein the second profile depth (b) measures at least 200 μm, preferably at least 350 μm.

METHOD FOR PROVIDING USER INTERFACE FOR MANUFACTURING PROSTHESIS, AND COMPUTER-READABLE RECORDING MEDIUM IN WHICH PROGRAM FOR EXECUTING SAME METHOD ON COMPUTER IS RECORDED

Resumen de: WO2026079533A1

This method for providing a user interface for manufacturing a prosthesis comprises: providing a guide image visualizing the inner surface of a prosthesis to be put on a prepared tooth; providing a parameter adjusting unit for adjusting a plurality of parameters for generating the prosthesis; displaying, on the guide image, a selected parameter image for explaining a parameter selected by a user from among the plurality of parameters; and generating a 3-dimensional image of the prosthesis on the basis of data set by the parameter adjusting unit.

DENTAL APPLIANCE, SYSTEM, AND METHOD

Resumen de: US20260102223A1

A dental appliance for a patient includes a body including a first surface and a second surface opposite to the first surface. The second surface defines a channel for receiving a plurality of teeth of the patient. The dental appliance further includes an arrangement of a plurality of features disposed on the first surface of the body. Each of the plurality of features includes a protrusion extending from the first surface opposite to the second surface; a depression extending partially from the first surface wards the second surface; or a through-hole extending from the first surface to the second surface. The arrangement of the plurality of features encodes a feature data representative of a dental appliance information of the dental appliance or a patient information of the patient.

MINIMALLY INVASIVE AND ENDOSCOPIC IN-VIVO BIOPRINTING SYSTEMS AND METHODS

Resumen de: AU2025215643A1

A system (100) may include a donor supply sub-system (110) configured to supply donor material (102) to a donor substrate (104). The system may include a material transfer sub-system (108) comprising a laser (200) configured to illuminate the donor substrate via a transfer beam (202). The system may include an instrument head (302) of a medical instrument (300) configured to house the donor substrate, wherein upon an illumination of the donor substrate, the donor material is transferred to receiver material in vivo.

METHOD AND APPARATUS FOR NON-INVASIVELY MESAURING BLOOD CIRCULATORY HEMOGLOBIN

Resumen de: US20260102066A1

A method and system for non-invasively determining continuous total hemoglobin data is provided. The method includes a) using a near infra-red spectrophotometric (NIRS) sensing device on a continuous basis to sense a subject's tissue, the sensing producing NIRS signals; and b) determining continuous total hemoglobin (THb) using the produced NIRS signals.

APPARATUS AND METHOD FOR 24-HOUR AMBULATORY BLOOD PRESSURE MONITORING WITH COMPENSATION BASED ON POSTURE AND/OR ACTIVITY DETECTION

Resumen de: US20260102067A1

0000 An apparatus for monitoring a person's health conditions. The apparatus has one or more biometric sensors for periodically measuring the person's biometric data, one or more activity sensors for periodically measuring the person's activities, and a circuit functionally coupled to the one or more biometric sensors and the one or more activity sensors, the circuit having an artificial intelligence (AI) engine configured for using a trained AI model for analyzing the person's health condition based on the measurement data collected from the one or more biometric sensors and the one or more activity sensors.

SYSTEMS, APPARATUSES, AND METHODS FOR CREATING TISSUE INTERFACES

Resumen de: US20260102288A1

A system for creating a tissue interface. The system includes a scanner, at least one processor, and a memory. The scanner is configured to scan a tissue site and generate a signal corresponding to a topography of the tissue site. The at least one processor is configured to receive the signal corresponding to the topography of the tissue site and to receive user input at a user interface identifying a therapy to be applied at the tissue site. The memory is coupled to the at least one processor and is configured to store instructions that when executed by the at least one processor in response to receiving the signal corresponding to the topography of the tissue site cause the system to transform the signal corresponding to the topography of the tissue site into a model site surface and generate a model tissue interface.

3D BIOPRINTING PLATFORM FOR GENERATION OF FUNCTIONAL PRIMARY AND HPSC-DERIVED ORGANOIDS IN HYDROGEL CONSTRUCTS

Resumen de: WO2026080718A1

The disclosed concept includes the preparation and use of biocompatible bioinks, as well as techniques and methods therein for bioprinting, preparing and 3D printing primary cells and patient-specific cells and forming functional soft tissue in a three-dimensional construct form that incorporates the cells and mimics native tissues. The biocompatible bioinks include alginate, methylcellulose, and primary or iPSC-derived cells in the form of single cells or aggregates. The bioprinted 3D construct includes one or more of the iPSC organoids, human islets, as well as TEPCs.

NOVEL 3D PRINTING SELF-STABILIZING CERVICAL INTERBODY FUSION CAGE

Resumen de: US20260102258A1

0000 A novel 3D (three-dimensional) printing self-stabilizing cervical interbody fusion cage is provided, including a fusion cage body, circular-arc notches arranged at four corners of a front side surface of the fusion cage body, and threaded openings are formed in interiors of the circular arc notches and screws are correspondingly mounted in the threaded openings. An inner wall of the fusion cage body is of a circular arc structure, and a reserved circular opening is formed in the middle position of the front side surface. Each of the circular arc notches is positioned to form an angle of 45° with a horizontal plane of each of the four corners of the fusion cage body. Screw are self-tapping screws with threads, and the threads of the screws are in fit with threads of the inner walls of the circular arc notches.

METAL OXIDE BIOLOGICAL IONOMER AND METHODS

Resumen de: US20260102509A1

A nanoparticle compound comprising buckminsterfullerene C60 bonded to ester functional groups of pyruvic, citric, and hyaluronic acids, with oxygen-bridged components selected from vanadium, gallium, and bismuth is provided. At least one component enables quantum-mechanical spin-wave activation. Ultrasonic irradiation activates the compound, inducing electrical induction for tissue healing and cell growth. The compound integrates with native and 3D-printed tissues, enhancing their properties through interpenetrating networks. It exhibits anti-inflammatory, antioxidant, and antibacterial effects, reinforces connective tissue, and modulates stem cell growth. The compound treats arthritis, enhances gut health and barrier function, supports bone health, improves voice quality, counters cancer cell proliferation, and mitigates osteoporosis. The gallium component creates an alkaline environment for calcium deposition, while vanadium enhances chondrogenic differentiation. Administration methods include topical application, oral ingestion, injection, and infusion through bandages or sutures. The compound serves as an adjuvant for analgesics, enhancing their delivery and efficacy.

SYSTEMS AND METHODS FOR BIOPRINTING CORNEAL STROMA EQUIVALENTS

Resumen de: WO2026078545A1

Synthetic corneal stroma are created though a bioprinting process. The bioprinting process utilizes Digital Light Processing (DLP) in the formation of the corneal stroma. A hydrogel is formed to serve as the basis for the DLP printing. The DLP printing process provides control exposure of the hydrogel to UV light. The bioprinting through the DLP printing process forms a synthetic corneal stroma.

3D SCANNING METHOD, SYSTEM AND APPARATUS FOR DENTAL APPLICATIONS

Resumen de: US20260102230A1

A method and device for aligning face scans with intraoral scans in dentistry applications. Digital intraoral scans capture the upper and lower arches and a bite registration. An Anterior Extension Device is affixed in the patient's mouth. A working scan of the upper arch scan is trimmed to remove the areas covered by the Anterior Extension Device. A rigid reference link extends between the Anterior Extension Device and base of the patient's nose. The working scan is rescanned to include the Anterior Extension Device and rigid reference link and patient's nose. A facial scan is taken while the patient is smiling. The rescanned working scan is aligned and merged with the facial scan on the basis of at least three points of reference on the patient's nose. A prosthetic device is designed using in combination the intraoral scans aligned with the facial scan.

OCULAR PHOTO-BIO-STIMULATION OPTICS

Resumen de: AU2024337161A1

A device providing ocular photo-bio-stimulation therapy, a biological technique to control or influence the activity of neurons or other cell types in, on or about the eye with light. As used herein ocular photo-bio-stimulation is an umbrella category of which photobiomodulation, optogenetics and phototherapy are forms thereof. The current invention relates, in part, to photobiomodulation therapy, which includes the utilization of nonionizing electromagnetic energy to trigger photochemical changes within cellular structures. The current invention relates, in part, to optogenetics. Optogenetics is a biological technique to control the activity of neurons or other cell types with light. The current invention relates, in part, to phototherapy, also known as light therapy or bright light therapy, which is a treatment that uses controlled exposure to artificial or natural light to treat medical conditions.

MULTI-FUNCTIONAL POLYMERIZABLE COMPOUNDS AND METHODS OF PRODUCING AND USING THE SAME

Resumen de: WO2026080633A1

The present disclosure provides synthesizing multi-functional polymerizable compounds and methods for the synthesizing the same. The methods include reacting a compound of Formula (Ia) with an epoxide of Formula (Ib) with quantitative conversion, requiring only an aqueous work-up for purification. Further provided herein are methods of producing polymerizable composition, methods of forming an article by additive manufacturing processes (e.g., via 3D printing), such as orthodontic appliances with increased stain resistance.

3D STRUCTURE-FUNCTIONAL DESIGN OF BIOMASS-DERIVED SOLAR PHOTOCATALYST FOR ANTIMICROBIAL EFFICACY AND CHEMICAL DEGRADATION AT AMBIENT CONDITIONS

Resumen de: US20260102758A1

The subject invention pertains a stable, three-dimensional (3D) photocatalyst composition comprising TiO2 doped with carbon derived from lignin. The photocatalyst composition has a stable, hollow, spherical or spheroid nanoparticle structure, which improves photodegradation under visible light irradiation over unmodified TiO2 photocatalysts. The subject invention also provides methods of preparing the photocatalyst, as well as methods using the photocatalyst to remediate contaminants such as pharmaceuticals, pathogens and persistent organic pollutants.

3D PRINTABLE ANTHROPOMORPHIC PHANTOM FOR MIMICKING THE DIELECTRIC PROPERTIES OF MAMMARY TISSUES AND USE THEREOF

Resumen de: WO2026078280A1

The present invention relates to a breast phantom, comprising: a first hydrogel that forms a simulated phantom of normal breast tissue and a second hydrogel that forms a simulated phantom of cancerous breast tissue, wherein the first hydrogel comprises cross-linked 2-hydroxyethyl acrylate and the second hydrogel comprises cross-linked methacrylate hyaluronic acid. The present invention also relates to the method of preparing said phantom and to its use.

SYSTEM AND METHODS FOR LOCATING DRIVERS OF ATRIAL FIBRILLATION

Resumen de: US20260102102A1

The present disclosure applies to methods of cardiac ablation that use an algorithm to determine where in the heart a driver of atrial fibrillation is located. Catheters with multi-electrode arrays are used to measure electrograms from cardiac signals wherein abnormal signals are identified as electrogram deflections with characteristic shapes. The electrogram deflections are compared to each other in pairs to determine which came first in time in order to determine the net direction of propagation of a fibrillatory wave. The signal that came first is assigned a positive point value so that once the plurality of electrograms have been compared, the signal with the highest point value can be identified as a driver of fibrillation. The data can be displayed graphically as a map of atrial fibrillation drivers on a 3D representation of a heart, allowing surgeons to quickly and easily identify where on the heart the driver is.

PATHOGEN MONITORING SYSTEM AND METHOD

Resumen de: WO2026080101A2

The portable sensor system (100) includes a containment portion (102) and a sensor portion (104). The containment portion (102) may include a shipping container such as a jar. The sensor portion (104) may include a cap (106) that may be selectively coupled with the containment portion (102). The cap (106) may include a battery module (108), a processing module (110), and a sensor module (112). In a specific example, the portable sensor system (100) may be provided in four layers (a battery module layer (108), a processing module layer (110), a sensor module layer (112), and a coupling mechanism layer (114). The coupling mechanism layer (114) may be configured to selectively lock the cap (106) to the containment portion (102). In a more specific example, one or more of the layers (108, 110, 112, 114) may be 3D printed. The portable sensor system (100) may be utilized as a smart-monitoring device for the presence of a pathogenic bacteria in the shipping container.

PREDICTION FUNNEL FOR GENERATION OF HYPO- AND HYPER-GLYCEMIC ALERTS BASED ON CONTINUOUS GLUCOSE MONITORING DATA

Resumen de: US20260102124A1

0000 Certain aspects of the present disclosure relate to methods and systems for providing decision support around glucose management for patients with diabetes. Time-varying inputs including blood glucose, meal intake information, and amount of infused insulin are processed using a machine learning model to obtain predicted glucose levels for a plurality of prediction horizons and uncertainties for the predictions. A confidence interval is generated for each prediction and the confidence intervals are compared to hypo- and hyperglycemic thresholds. If a confidence interval is entirely below or entirely above the hypo- and hyperglycemic thresholds, respectively, then a decision support output is provided.

SYSTEMS, METHODS, AND DEVICES FOR TARGET CONTROLLED INFUSION

Resumen de: US20260102564A1

0000 A system for programming infusion devices for target controlled infusion is disclosed. The system includes a docking station and one or more processors configured to determine a first infusion device docked with a docking station and accept user input of one or more of patient-specific parameters, drug-related parameters, and a desired target concentration of a therapeutic agent in a workflow on the first infusion device for programming a target controlled infusion (TCI) therapy. After receiving a particular set of parameters, the set of parameters can be copied to the second infusion device to pre-complete and bypass a number of workflow steps of a second workflow of another infusion device. When the second workflow is accessed, the number of workflow steps of the second graphical interface workflow are pre-completed and bypassed.

DEEP REINFORCEMENT LEARNING BASED ROBUST NEUROVASCULAR MAPPING

Resumen de: US20260105597A1

Systems and methods for generating a patient-specific vascular tree are provided. 1) one or more medical images of a patient and 2) a vascular tree template comprising a plurality of points are received. The plurality of points of the vascular tree template are iteratively adjusted based on the one or more medical images using one or more AI (artificial intelligence) agents to generate a patient-specific vascular tree for the patient. The patient-specific vascular tree is output.

Systems and Methods for Determining the Orientation of Motion-Sensing Devices During Physical Activity

Nº publicación: US20260102656A1 16/04/2026

Solicitante:

MOTION METRICS LTD [GB]

Resumen de: US20260102656A1

0000 A computer-implemented method for providing real-time performance feedback includes receiving uncalibrated time-series motion data generated by one or more motion sensors coupled directly or indirectly to an athlete while performing a downhill snow sport, the motion sensor(s) having an unknown rotational orientation relative to the athlete; determining an estimated rotational offset of the motion sensor(s) relative to a body-segment coordinate frame of the athlete, the rotational offset determined using a calibration model; transforming, by the one or more processors, the uncalibrated time-series motion data to calibrated time-series motion data according to the estimated rotational offset, the calibrated time-series motion data aligned with the body-segment coordinate frame; and processing the calibrated time-series data, with the one or more processors, to determine one or more metrics for the athlete.