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179
resultados
Última actualización
16/06/2025 [07:19:00]
Resultados 75 a 100 de 179
Resumen de: CN120078618A
本发明公开一种牙齿修复装置，涉及医疗器械技术领域，包括支撑板，支撑板顶面固定安装有操作台，操作台上设有用于设置参数的触摸显示屏，操作台内安装有3D打印机，操作台上开设有第二凹槽，第二凹槽内放置有扫描仪，扫描仪用于对患者口腔进行非接触式扫描，操作台远离扫描仪的一侧开设有第一凹槽，第一凹槽内放置有安装笔，安装笔用于将修复体装入需要修复的牙齿内，操作台上开设有盛放槽，盛放槽用于放置修复体。本发明能够一次性完成从扫描到安装的全过程，显著缩短治疗周期，提高效率；减少就诊次数和手术创伤，提升患者治疗体验，增强舒适度；通过安装笔对修复体进行固定安装，保证与牙齿良好的贴合度。
Resumen de: CN120081983A
本发明提供了一种光敏树脂组合物、树脂牙及树脂牙的制备方法。所述光敏树脂组合物包括如下质量百分比的组分：聚氨酯(甲基)丙烯酸酯类低聚物20～45％、单官能(甲基)丙烯酸酯单体5％～15％、多官能(甲基)丙烯酸酯单体10～30％、填料15～55％、引发剂1％～5％、紫外线吸收剂0.02％～0.12％和光稳定剂0.1％～0.3％。所述树脂牙由所述光敏树脂组合物通过光固化3D打印制备得到。采用本发明提供的光敏树脂组合物制备的树脂牙具有在口腔环境下力学性能稳定，在咀嚼循环条件下的耐疲劳性能良好的优点。
Resumen de: CN120078942A
本发明公开了一种可紫外光固化的仿生半月板及其制备方法，涉及半月板组织替代物技术领域，仿生半月板的形状为模拟天然半月板的C形结构，仿生半月板的C形结构由前至后依次分为前部、中部和后部，仿生半月板的表面强度沿着前部到中部方向梯度增加，沿着中部到后部方向梯度下降；仿生半月板的C形结由内至外依次分为内侧、中间和外侧，仿生半月板的表面强度在前部和中部区域沿着外侧到中间方向梯度增加，沿着中间到内侧方向梯度下降；仿生半月板的表面强度在后部区域沿着外侧到内侧梯度下降；仿生半月板采用可紫外光交联的材料固化后制得。本发明使用紫外光固化材料制备不可降解的具有梯度强度分布的仿生半月板，其与天然半月板的力学性能相近。
Resumen de: WO2024040387A1
A microneedle array (101) comprises a surface (102) and two or more microneedles (104, 105) extending from the surface, wherein at least one of the microneedles has a different shape and/or length compared with a shape and/or length of at least one other of the microneedles. Furthermore method of making.
Resumen de: CN120078956A
促进骨质疏松性骨缺损修复的人工骨及其制备方法，属于生物医学材料技术领域。本发明的人工骨由89.65wt%‑89.85wt%的聚乳酸‑羟基乙酸共聚物、9.85wt%‑10.15wt%的纳米羟基磷灰石以及0.1wt%‑0.5wt%的唑来膦酸复合而成。该人工骨中，纳米羟基磷灰石和唑来膦酸在聚乳酸‑羟基乙酸共聚物中均匀分散，结合人工骨表面的多孔结构，有利于成骨细胞在表面的附着，有利于新生骨组织的长入；唑来膦酸的膦酸根能够与纳米羟基磷灰石螯合生成稳定的化学键，将其引入到聚乳酸‑羟基乙酸共聚物中，可以实现唑来膦酸的有效负载，唑来膦酸的有效负载能够抑制破骨细胞过度活化导致的骨吸收增多，修复骨质疏松性骨缺损。
Resumen de: CN115740495A
The invention relates to a method for 3D printing of a bone trabecula oral implant. The bone trabecula oral implant comprises an implant base body and a bone trabecula porous structure which are integrally formed. The bone trabecula porous structure is positioned in the axial middle section of the implant base body; and the implant base body is provided with an external thread. The printing method comprises the following steps: obtaining an oral implant 3D model with a bone trabecula porous structure through three-dimensional design software; carrying out molding manufacturing, sand blasting and annealing treatment by utilizing an SLM technology to obtain a bone trabecula oral implant primary product; and forming a tantalum metal coating on the surface of the primary product of the bone trabecula oral implant by using a vapor deposition technology to obtain the bone trabecula oral implant with the tantalum coating. The bone trabecula oral implant obtained by the method is high in density and mechanical strength, favorable for the implant to exert a good repairing effect, and excellent in application prospect.
Resumen de: WO2024084040A1
The disclosure relates to an aqueous bioink solution for use in light-based bioprinting applications, comprising: (a) 0.5-95 wt % water-soluble prepolymer; (b) 0.001-5 wt % biocompatible metal acylphosphinate photoinitiator; (c) 0.001-10 wt % biocompatible light absorber; and (d) 5 to 99.5 wt % solvent. The disclosure further relates to a method of using the aqueous bioink solution including living cells and a method of using the aqueous bioink solution without living cells (acellularly).
Resumen de: CN120078562A
本发明涉及一种防移位自适应自锁式人体管腔支架与制作方法，属于医疗器械领域。本发明包括支架单元和连接单元，相邻支架单元通过连接单元连接，其结构特点在于：所述支架单元包括呈菱形结构设置的主体框架、以及设置在主体框架内部的连接横梁、过渡横梁和榫卯横梁，所述连接横梁、过渡横梁和榫卯横梁依次连接，所述连接横梁和榫卯横梁均与主体框架连接，两个榫卯横梁上均设置有多个榫头，相邻榫头之间形成榫槽，其中一个榫卯横梁上的榫头与另一个榫卯横梁上的榫槽连接，其中榫头的数量不少于3个，榫槽的数量不少于2个。
Resumen de: CN120078532A
本发明涉及骨性Ⅲ类上颌发育不足的矫治器技术领域，尤其涉及一种基于数字化可视化颌位重建技术的矫治器制作方法，所述矫治器包括基底和颌垫，矫治器的制作包括以下步骤：S1：获取患者相关数据及第一次口扫数据，确定矫治器方案；S2：获取患者的静态咬合状态，确定初步的咬合目标位置，并获得第二次口扫数据；S3：将所述第一次口扫数据和所述第二次口扫数据分别导入至设计软件中，生成数字化模型；S4：通过数字化颌架确定最终颌位；S5：设计基底模型，并3D打印；S6：设计颌垫模型，并3D打印；本方法制作的矫治器组织面能完美匹配患者的牙齿外形，咬合记录目标位置更加符合人体生物学基础，设计更为精确，并可有效防止矫治器脱落。
Resumen de: CN222929860U
本实用新型公开了一种可拆卸3D打印义齿的个性化适配卡扣，包括固定在义齿本体两侧的用于与相邻牙齿卡设安装的卡环，还包括设置在义齿本体上的用于义齿本体安装过程中与相邻牙齿之间适配挤压的适配挤压组件。本实用新型的一种可拆卸3D打印义齿的个性化适配卡扣，义齿在安装的过程中，通过传动，使两组挤压板的一端分别与义齿本体两侧相邻的牙齿相抵，通过相抵作用，对安装后的义齿本体进行自动的适配挤压，且在挤压适配的过程中，推动弹簧的弹力作用，使两组挤压板保持与相邻两组牙齿相抵，避免因使用者口腔的变化造成安装后义齿本体与相邻的牙齿之间产生间隙，便于义齿本体以更加稳定的卡扣方式安装固定。
Resumen de: CN120078530A
本发明属于口腔修复数字化领域，具体涉及一种基于数字化导板引导的前牙分层树脂充填修复方法。包括以下步骤：S1、获得基牙预备体的三维数字化模型；S2、利用口腔计算机辅助设计软件逐层生成缺损部分的牙本质形态的数字化模型；S3、在最后一层牙体缺损部分牙本质形态的数字化模型上完成牙釉质层形态的设计；S4、设计覆盖缺损牙邻牙的盖壳式导板，并对各盖壳式导板进行编号；S5、将各层模型和导板3D打印出来，并检查导板的就位情况；S6、在各级导板中填充相应的牙本质树脂和牙釉质树脂，将充填树脂的导板复位至口腔牙列，通过光照固化完成分层树脂充填。本发明优化了流程，简化了操作，充分利用数字化技术的优势保证了操作精度。
Resumen de: US2022370300A1
Radically polymerizable dental material, which contains at least one ABA or AB block copolymer, preferably at least one monofunctional, radically polymerizable monomer (a) and preferably at least one radically polymerizable urethane di(meth)acrylate telechel (b).
Resumen de: EP4523890A2
The invention relates to a system for producing pharmaceutical objects, such as tablets, granules and capsules, via 3D printing. The system comprises a 3D printing machine (2) with a mechanical system (3) movable in one or more directions, at least one print head (5) with at least one nozzle (37) being movable by the mechanical system (3) and a base system (4) carrying a print base (6) for receiving a prepared mixture (27) applied by the print head (5) and comprising formatted print locations (49) on the base (6) for shaping the pharmaceutical object. The formatted print locations (49) can be adapted to receive a blister such that the pharmaceutical objects can be printed directly inside the blister. The system can further comprise a closing device for applying a sealing membrane or film to hermetically seal the blister after the printing is completed. The invention further relates to a method for producing pharmaceutical objects with the system.
Resumen de: AU2025202262A1
The current disclosure is directed to an impact resistant material made from a novel melanin composite. It has been found that using these composites allows for the production of effective ballistic protection and blast containment materials.
Resumen de: JP2024045166A
To provide a method for forming articles by additive manufacturing using tantalum powder.SOLUTION: There is provided a method for forming an article, wherein the method comprises a step of additive manufacturing to form the article by utilizing the tantalum powder to form the shape of the article or part thereof, and wherein the tantalum powder has following characteristics: a. spherical shape with an average aspect ratio of from 1.0 to 1.25; b. a purity of tantalum of at least 99.99 wt.% Ta based on total weight of the tantalum powder, excluding gas impurities; c. an average particle size of from about 0.5 micron to about 250 microns; d. an apparent density of from about 4 g/cc to about 12.3 g/cc; e. a true density of from 16 g/cc to 16.6 g/cc; and f. a Hall flow rate of 20 seconds or less.SELECTED DRAWING: Figure I
Resumen de: KR102815488B1
본 개시는 다이렉트 3D 프린팅용 광경화성 형상복원 고분자성 조성물 및 이를 이용하여 제조한 치아 교정장치에 관한 것으로, 보다 상세하게는 제1 온도범위에서 치아교정에 적합한 강성, 강직성, 및 탄성을 가지고, 상기 제1 온도범위와 상이한 제2 온도범위에서 원형복원 특성을 가지는 다이렉트 3D 프린팅용 광경화성 형상복원 고분자성 조성물 및 이를 이용하여 제조한 치아 교정장치에 관한 것이다.
Resumen de: CN120053751A
本发明属于生物材料技术领域，具体涉及一种骨修复用3D打印聚乳酸复合支架及其制备方法。其中，骨修复用3D打印聚乳酸复合支架由以下原料制备而成：PLA/Mg‑ZrO2和BP/STAC；本发明采用PLA/Mg‑ZrO2作为3D打印支架，在PLA/Mg‑ZrO2支架表面形成BP/STAC复合涂层，制备得到骨修复用3D打印聚乳酸复合支架，PLA/Mg‑ZrO2支架具有模仿天然骨骼的分级孔隙率，PLA具有良好的生物相容性，Mg‑ZrO2的加入增强了PLA支架的力学强度和韧性，BP/STAC的复合涂层进一步增强了复合支架的力学性能，且有助于细胞附着和生长，加速了骨细胞的增殖和分化，促进新骨的形成。
Resumen de: WO2024033402A1
The invention relates to a maxillary modeller (2) intended to be worn, in a service position, on a dental arch of a user in order to modify the shape of the palate, the maxillary modeller being one-piece and removable and comprising: - a central palatal portion (22) configured to be in contact with the user's palate when the maxillary modeller is in the service position; and - a first and a second dental portion (24; 26) each comprising at least one, preferably multiple cavities configured to receive teeth of the user when the maxillary modeller is in the service position, the first and second dental portions extending on either side of the central palatal portion, the central palatal portion being configured so as to exert on the palate, in the service position, forces suitable for modifying the shape thereof.
Resumen de: AU2023271390A1
Aspects of the disclosure include a fabrication platform for supporting a bioprinted fiber structures during printing, patterning, and/or processing, comprising a frame with a plurality of posts for securing a cross-linkable fiber during printing thereof, and where a continuous length of the cross-linkable fiber is printed around a plurality of posts during the 3D bioprinting process. The fabrication platform enables the cross-linkable fiber to be suspended during one or more of printing, patterning, and/or processing. In this way, the bioprinted fiber structure comprises a uniform outer surface, and can be easily modified and/or further processed after printing and patterning are completed.
Resumen de: CN119546355A
A biological material comprising a first porous polymer, a second non-porous polymer, and a therapeutic agent, and a method of using the same for treating a condition are disclosed. The biomaterials disclosed herein may be, for example, surgical articles. Implanting the biomaterials disclosed herein in a subject can treat, for example, cancer.
Resumen de: WO2025111433A1
A contrast marker for use in medical imaging comprising: an elongated body comprising a first end and a second end, the second end opposite the first end, wherein a longitudinal axis is defined between the first end and the second end. A first portion of the elongated body is formed of a radiopaque material and a second portion of the elongated body is formed of a polymeric material, the first portion extending in a direction parallel with the longitudinal axis. The marker may be configured to receive a fluidic contrast medium so as to be imageable under CT and MR imaging. Also provided herein are methods of making the contrast marker. Further provided herein is an applicator plug for sealing a tubular brachytherapy applicator.
Resumen de: WO2025111571A1
An apparatus includes a 3D model of a soft tissue. The 3D model includes an anatomically correct outer wall defining an internal cavity. The 3D model further includes a reduced scale duplicate of the outer wall positioned with in the internal cavity. The reduced scale duplicate divides the internal cavity into an inner chamber within the reduced scale duplicate and an outer chamber between the reduced scale duplicate and the outer wall. The 3D model further includes ports extending from each of the inner chamber and the outer chamber to an exterior of the outer wall. Each port is configured to connect to a device that is configured to inject liquids into each of the inner chamber and the outer chamber.
Resumen de: WO2025110384A1
The present invention relates to a composite resin for esthetic restorations with improved antimicrobial properties and polymerization depth, and a manufacturing method therefor, wherein the compositive resin comprises urethane dimethacrylate (UDMA), bisphenol A-glycidyl methacrylate (BIS-GMA), bisphenol A dimethacrylate ethoxylated (BIS-EMA), triethylene glycol dimethacrylate (TEGDMA), a photoinitiator, a co-photoinitiator, a filler, barium glass, an accelerator, an antioxidant, a discoloration inhibitor, and an antimicrobial agent in addition to lysozyme. With the enhanced polymerization depth, the resin can be applied as a bulk-fill resin, and the excellent antimicrobial properties thereof provide resistance against bacteria and viruses. After polymerization, the resin exhibits a flexural strength exceeding 80 MPa, which is a level required by the Korean Ministry of Food and Drug Safety.
Resumen de: WO2025107170A1
Disclosed are a bio-ink for promoting microangiogenesis, a method for preparing same, and use thereof. The bio-ink is prepared by the following method: 1) preparing a filamentous microgel with a diameter within 20 microns from a sacrificial-phase material A as a porogenic template; 2) seeding vascular endothelial cells and perivascular cells on the surface of the filamentous microgel to give a hydrogel microfilament with the surface loaded with cells; and 3) mixing the hydrogel microfilament with the surface loaded with cells with a solution of a matrix-phase material B to give the bio-ink for promoting microangiogenesis. The bioprinting using the bio-ink can construct a capillary-like structure and cross-scale microvessels. The present invention can achieve the preparation of a micro-channel porous hydrogel structure with an average diameter of 20 microns or less and controllable porosity and the formation of a capillary-like network structure.
Nº publicación: CN222917965U 30/05/2025
Solicitante:
上海普利生三维科技有限公司
Resumen de: CN222917965U
本实用新型涉及一种负压微针给药装置，包括：壳体，壳体的顶部设置有注射器接口，注射器接口用于连接外部的注射器；壳体的底部设置有凹槽和凸起，凸起用于和皮肤贴合；壳体的内部设置有储药腔体和负压腔体，储药腔体和注射器接口连通；壳体的表面设置有负压接口，负压腔体的一端通过负压接口和外部的抽负压装置连接；凹槽的表面设置有通孔，负压腔体的另一端通过通孔和外部连通；微针，包括针头和中空的流道，流道设置在针头的内部，流道和储药腔体连通，针头凸出于凹槽的表面向外延伸，针头用于刺破皮肤。本实用新型可以有效地吸引皮肤靠近针头并自动刺破皮肤给药，提高了给药效果和患者的使用体验。
BOPI
Sede Electrónica
