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157
resultados
Última actualización
20/10/2024 [07:13:00]
Resultados 75 a 100 de 157
Resumen de: US2024325174A1
A prosthetic device includes a polymer lattice structure. The lattice structure includes a first surface arranged to face toward a residual limb, a second surface arranged to face away from the residual limb, a thickness between the first and second surfaces, and a variable lattice density across the thickness.
Resumen de: US2024326322A1
A method for universal contactless printing comprises depositing a first droplet into a sound field, curing the droplet to form a cured droplet, depositing a second droplet, and securing the second droplet to previously cured droplet by curing the second droplet. The method of contactless printing can be repeated to form a complex three-dimensional structure. The first droplet that is deposited can be secured to a moveable structure by curing the first droplet to the moveable structure. The moveable structure can be moved to place a next droplet to be deposited and cured.
Resumen de: US2024325160A1
An orthopaedic knee prosthesis includes a femoral component having a metal base with a polymer articular layer molded thereto. A method for making a metal-reinforced femoral component of an orthopaedic knee prosthesis is also disclosed.
Resumen de: US2024325120A1
Device for the digitization and manufacturing of dental models, for replicating the cavity and position of the implant connection in plaster and digital 3D models, having an analog, a fixing element and a multipurpose accessory, as a reference when digitizing and as an aid when inserting the analog in and removing it from the model. The analog, the fixing element and the accessory are adapted for fixing the analog on the 3D printing model and/or connecting the analog to the accessory. The external surface of the analog combines cylindrical portions and flat vertical and horizontal faces, which define positioning surfaces, for use as a scan analog. And, for plaster models, the device includes a protective cover for the analog.
Resumen de: US2024325123A1
Example dental assemblies and methods involve snap-fitting a denture or other dental prosthesis to a patient's jaw. In some examples, an implant is anchored to the jaw, an abutment is screwed to the implant, and a head of the abutment snaps directly into a pocket created in the dental prosthesis. In some examples, a polymeric cap couples the abutment's head to the pocket. Based on coordinate data from a CT or intraoral scanner, the pocket can be created by CNC milling or 3D printing. The method eliminates the need for bonding a metal housing or casing to the dental prosthesis.
Resumen de: US2024325117A1
Provided herein are curable compositions for use in a high temperature lithography-based photopolymerization process, a method of producing crosslinked polymers using said curable compositions, crosslinked polymers thus produced, and orthodontic appliances comprising the crosslinked polymers.
Resumen de: US2024325069A1
In an example, a monopolar electrosurgical electrode includes an electrosurgical substrate including an electrically conductive material extending in an axial direction from a proximal end to a distal end. The electrosurgical substrate includes an electrosurgical blade. The electrosurgical blade includes (i) a first lateral surface, (ii) a second lateral surface opposite the first lateral surface, (iii) a first major surface extending between the first lateral surface and the second lateral surface on a first side of the electrosurgical blade, and (iv) a second major surface extending between the first lateral surface and the second lateral surface on a second side of the electrosurgical blade that is opposite the first side. The monopolar electrosurgical electrode also includes a first electrode sensor embedded between a plurality of electrical insulation layers on the first major surface of the electrosurgical blade.
Resumen de: US2024325127A1
Systems and techniques for designing a digital dental matrix with improved interproximal contacts are disclosed including generating a digital three-dimensional model of a future dental anatomy of a patient, the future dental anatomy representing an intended shape of at least one tooth of the patient, selecting one or more pairs of adjacent teeth in the 3D model, for each selected pair of teeth, determining a location and orientation in the interproximal space of the adjacent teeth to insert a digital 3D geometry having one or more initial parameters, and inserting the digital 3D geometry at the determined location and orientation.
Resumen de: US2024327793A1
The present disclosure relates to cell cultured adipose tissue. In one embodiment, the cultured adipose tissue is produced by culturing adipose cells in a culture media in vitro, harvesting the adipose cells after a desired amount of adipose cells are produced, and aggregating the harvested adipose cells to provide the cultured adipose tissue. In some embodiments, aggregating the harvested adipose cells comprises mixing the harvested adipose cells with a hydrogel or binder in a three-dimensional (3D) mold. In other embodiments, aggregating the harvested adipose cells comprises cross-linking the harvested adipose cells in a 3D mold. The cultured adipose tissue have a defined 3D shape and a size on the macroscale. In some embodiments, the cultured adipose tissue may be a food product.
Resumen de: US2024330104A1
Systems and methods are described herein for fitting of a dental analog. In an embodiment, a test block may be printed that includes a number of analog pockets of different sizes. A dental analog may be tested within the analog pockets to determine which analog pocket provides the best fit. Once the best fitting analog pocket is identified, a corresponding library file describing the geometry of that analog pocket is identified, and a dental prototype model may be 3D-printed using analog pocket geometry based on the analog library file. By printing using common printing parameters and the identified analog library file, the resulting printed dental prototype provides the same fit as the analog pocket identified within the test block. This use of a test block reduces or eliminates the need for iterative cycles of printing and testing multiple printed dental prototypes.
Resumen de: AU2022395642A1
The present invention relates to a printing apparatus for additive manufacturing methods, comprising: one or more print heads (1, 2), which each comprise a printing nozzle, the print head or print heads being optionally vertically movable; and a print bed which has a print table that is movable in a horizontal direction and optionally in a vertical direction and comprises a printing surface (3), the print table having an optical device (4) which is designed to capture an optical reproduction of the printing nozzle or printing nozzles at least from below. The invention also relates to a method comprising automatic position calibration of the printing nozzle(s) for the additive manufacturing of objects, preferably pharmaceutical administration forms, using the apparatus according to the invention.
Resumen de: WO2023094585A1
The invention relates to a method for producing a medical product, comprising the following step: a) additively building or manufacturing at least one functional element on a surface of a base body, the at least one functional element being connected to the base body after carrying out step a). The invention also relates to a medical product (1) produced by the method.
Resumen de: EP4438003A1
Device for the digitization and manufacturing of dental models, for replicating the cavity and position of the implant connection (0) in plaster and digital 3D models (m), comprising an analog (1), a fixing element (2) and a multipurpose accessory (3), as a reference when digitizing and as an aid when inserting the analog in and removing it from (1) the model (m); the analog (1) being provided with holes (10, 11) with fixing means and the fixing element (2) and accessory (3) with complementary fixing means (20, 30) for fixing the analog (1) on the 3D printing model (m) and/or connecting the analog (1) to the accessory (3). The external surface of the analog (1) combines cylindrical portions and flat vertical (12) and horizontal (13) faces, which define positioning surfaces, for use as a scan analog. And, for plaster models, it comprises a protective cover for the analog (1).
Resumen de: CN118302289A
There is provided a method of producing a bioactive polymer filament, the method comprising: providing a base polymer powder and a bioactive copolymer; mixing the base polymer powder with a bioactive copolymer to obtain a mixture; and extruding a bioactive polymer filament from the mixture at an extrusion temperature parameter based on a predetermined melting/softening temperature of the bioactive polymer and a predetermined degradation initiation temperature of the bioactive polymer; and performing post-extrusion thermal analysis on the extruded bioactive polymer filaments to assess the initial degradation of the bioactive copolymer in the filaments. Also provided are bioactive polymer filaments obtained by the method and a three-dimensional printing method based on fused filament manufacturing (FFF) or fused deposition modeling (FDM).
Resumen de: CN118369066A
Embodiments describe systems and methods for manufacturing a dental appliance and performing a quality assessment of a dental appliance. In one embodiment, a method of manufacturing a dental appliance includes receiving a feature of the dental appliance at a holder, the feature including a first surface having a first shape, where the holder holds the feature of the dental appliance at a reference position. The method further includes automatically placing an object against the feature at the reference position using the robotic arm, where the object includes a second surface having a second shape that mates with the first shape. The method further includes applying a pressure to press the object against the feature of the dental appliance, and bonding the object to the feature of the dental appliance while applying the pressure.
Resumen de: US2024166900A1
This relates to a hydrogel precursor composition and to a bioink obtainable from the hydrogel precursor composition, as well as a method of preparing and using the same. More specifically, This also relates to a bioink that contains a catechol grafted and spontaneously crosslinked hydrogel including cells, and to its use in 3D bioprinting and to a method of preparing the same.
Resumen de: WO2023089113A1
The invention relates to a patient-specific implant (5) for insertion into a body cavity of a patient, for example into the round window niche of the middle ear. The invention also relates to a method of manufacturing such an implant (5).
Resumen de: CN118718098A
本发明公开了一种牙种植体及其制备方法，属于牙修复材料技术领域。牙种植体包括钛金属主体，钛金属主体分为上段、中段和下段，上段和下段表面具有螺纹结构，中段具有镂空结构；螺纹结构和镂空结构的表面均包覆有功能涂层，功能涂层由内之外依次为掺锶纳米羟基磷灰石层和PVA层。本发明中的牙种植体的上段和下段够增加种植体与周围组织的接触面积，由此增强种植体的稳定性；牙种植体的中段为镂空结构，可以使其与周围骨组织的弹性模量更加匹配；而且，镂空结构为有利于营养物质的输入、代谢产物的输出以及血管的长入，从而促进骨整合过程；牙种植体表面涂覆有掺锶羟基磷灰石层可以提高细胞的粘附性，增加种植体的生物活性。
Resumen de: CN118720142A
本发明公开了一种在增材制造Ti6Al4V植入物结构表面制备抗菌涂层的方法，包括如下步骤：S1：基于选区激光融化技术，制备具有互联互通孔隙的Ti6Al4V支架；S2：配置化学抛光溶液，包括硝酸、氢氟酸、去离子水；S3：将Ti6Al4V支架放置在化学抛光溶液中抛光，抛光后取出进行清洗、干燥；S4：将聚乳酸浸泡在二氯甲烷中静置24h形成胶体溶液；S5：取出锌粉颗粒，将锌粉颗粒与S4中得到得胶体溶液用磁力转子混合，制备得到锌粉油墨；S6：采用浸渍提拉的方法，先将Ti6Al4V支架浸渍在锌粉油墨中，然后将Ti6Al4V支架从锌粉油墨中提出，全程保持风扇吹动，促进锌粉油墨干燥；S7：将Ti6Al4V支架放置在真空烧结炉中，在350℃~420℃温度下保温30min~120min，取出后清洗、干燥。
Resumen de: CN118717768A
本发明属于生物医疗技术领域，公开了一种用于治疗类风湿关节炎的生物制剂制备方法及系统，包括：方制备R4F‑NM@F127纳米颗粒，并通过Giemsa染色和透射电镜(TEM)对中性粒细胞的纯度和形态进行检测；R4F‑NM@F127‑TMP的纳米载体优化；使用超声分散技术将R4F‑NM@F127‑TMP均匀分散于水中，与GelMA水凝胶混合，形成适于3D打印的生物墨水；混合凝胶支架的力学与药物释放性能评估；在胶原诱导性关节炎(CIA)小鼠模型中，使用3D打印的水凝胶支架负载川芎嗪进行治疗。本发明结合了3D生物打印技术和纳米药物递送系统，以达到精准治疗的目的。预期，能够为RA患者带来更有效的治疗选择，也将为自身免疫性疾病的治疗提供重要的科学和技术基础。
Resumen de: CN118717370A
本发明提供了一种3D打印多方向低刚度高强度匹配且高吸能可调金属骨支架及其制备方法，所述金属骨支架的整体结构由Primitive极小曲面和弹簧组成，弹簧位于任意两个极小曲面结构处，高弹性弹簧的引入，使得整体结构具有多方向调控低刚度和高强度。同时完整的极小曲面结构提高了整体结构的生物成骨性能。两种结构端面连接，避免了应力集中现象，具有高的疲劳性能。弹簧结构和Primitive极小曲面结构法中心线重合，随着压缩应变的增大，承载可转为极小曲面结构，使骨支架具有低刚度匹配和高吸能性。因此，本发明设计的金属移植骨支架具有优异生物成骨性，多方向低刚度高强度匹配且高吸能，适应于人体骨的生物和力学性能。
Resumen de: CN118717644A
本发明涉及一种3D打印的肠道递送载体及其制备方法与应用。基于天然来源的纤维素及其衍生物，通过3D打印技术构建具有延长体内滞留、促进益生菌体内增殖和定植的三维管状益生菌递送载体。其中，所述的3D管状结构通过设置其外在的形态结构和表面纹路，促进其与肠道的相互作用，进而有效延长其在体内的生物滞留。与此同时，本发明具有良好的生物安全性，可以维持较高的益生菌生物活性，进而调节肠道微环境，改善肠道菌群的紊乱相关疾病的病症。本发明的递送载体具有调节和改善菌群结构，改善菌群代谢，促进肠道稳态修复的疗效，可以显著改善肥胖、肠炎等疾病，为肠道相关疾病的解决提供了一种新的解决策略。
Resumen de: AU2023235004A1
A method For manuFacturing a perFusable three-dimensional tissue model, containing therein a channel distributed across its entire structure, enabling the Flow oF Fluids, wherein bioprinting a vascular system with the extrusive method using bioink, the walls opening and closing the channel in its upper part being printed parallel to the channel axis, and bioprinting oF the model body with the extrusive method using bioink, the bioink For printing the body being diFFerent From the bioink used For bioprinting the vessels, placing the resulting system in an incubator, in a temperature in which bioink For printing the vascular system undergoes melt, removing the bioink, optionally, causing growth in the channel by means oF cells in a medium, wherein, the cross-section oF the channel being the same as the cross-section oF native vessels present in a living organism. The inventions relates to a bionic model with a perFusable system.
Resumen de: AU2023233429A1
A reinforcing and sealing construction for a bioprinted tissue model, which comprises a casing and sealing bioink, the casing comprising an inner module comprising a casing base (1) and a perforated cover (2), and an outer module comprising a container (3) comprising technological valves (5), an outer cover (4) and plugs (6) for technological valves (5). The invention also relates to a method for assembling the reinforcing and sealing construction.
Nº publicación: CN118717319A 01/10/2024
Solicitante:
北京医瓴科技有限公司
Resumen de: CN118717319A
本发明公开了一种颌位儿童隐形矫正器制品的制备方法，包括如下制备步骤：制作患者牙齿初始状态数字化模型；制作患者牙齿目标位置数字化排牙模型；设计牙齿移动组合步骤的分组设计；3D打印树脂牙齿模型；热压技术制作仿生组合膜片上下颌隐形矫正器；结合临床咬合记录完成上下颌矫正器粘接。该发明可以实现矫正器传递出更有利于儿童牙槽骨及牙周组织改建的生物力，并通过一体式设计增强儿童牙齿支抗力与固位力，精准颌位设计则又能有效实现各类牙齿及颌骨矫治目标，从而达到有效排齐儿童前牙并且不影响牙根继续发育的目的。
BOPI
Sede Electrónica
