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回転フレーム装置及び生体適合性足場構築物

NºPublicación:  JP2025108455A 23/07/2025
Solicitante: 
エンボディ,インコーポレイテッド
JP_2025108455_PA

Resumen de: CA3203473A1

A biocompatible scaffold construct includes a plurality of collagen fiber strands, a first portion of which have been coated by a first biocompatible solution and, optionally, a second portion of which have been coated by a second biocompatible solution different than the first biocompatible solution. The coatings may include cells. And the scaffold is constructed on rotating frame collectors.

SYSTEMS AND METHODS FOR MODIFYING SURFACES OF ADDITIVELY MANUFACTURED OBJECTS

NºPublicación:  EP4587222A2 23/07/2025
Solicitante: 
ALIGN TECHNOLOGY INC [US]
Align Technology, Inc
CN_120202085_PA

Resumen de: US2024091906A1

Systems and methods for processing additively manufactured objects are described herein. In some embodiments, for example, a system includes a controller configured to provide one or more control signals; a heater coupled to the controller, where the heater comprises one or more heating elements arranged to heat a blasting medium in response to the one or more control signals; a chamber coupled to the controller, where the chamber comprises an agitatable drum shaped to receive a plurality of additively manufactured objects, and to agitate the plurality of additively manufactured objects in response to the one or more control signals; and an applicator coupled to the controller, where the applicator comprises a nozzle operative to direct, in response to the one or more control signals, a plurality of thermally conductive particles in the blasting medium toward the plurality of additively manufactured objects within the agitatable drum.

三维打印牙模

NºPublicación:  CN223126679U 22/07/2025
Solicitante: 
上海普利生三维科技有限公司
CN_223126679_U

Resumen de: CN223126679U

本申请提供了一种三维打印牙模,包括:主体部,所述主体部的底部位于第一平面内,并且所述底部为开放式,所述主体部的内部具有容纳腔,所述主体部具有外壁;支撑部,位于所述容纳腔内,所述支撑部在所述第一平面上的投影为蜂窝状,并且所述支撑部具有沿垂直于所述第一平面的第一方向从所述底部延伸到所述外壁的支撑壁;其中,所述支撑壁在所述第一方向上至少部分的厚度小于所述外壁的厚度。

一种3D打印三叉神经痛球囊压迫穿刺导板

NºPublicación:  CN223126615U 22/07/2025
Solicitante: 
自贡市第三人民医院
CN_223126615_U

Resumen de: CN223126615U

本实用新型涉及医用辅助器械,一种3D打印三叉神经痛球囊压迫穿刺导板,包括导板本体和导向管;所述导向管与导板本体之间通过支撑悬臂连接,所述导向管为半圆管状。本实用新型采用半圆管形式的导向管,其在穿刺完成后,能够方便快速的与穿刺器械进行分离,穿刺完成无需再进行导向时,可以在不抽出穿刺器械的基础上实现导向管与穿刺器械的快速脱离,降低了穿刺导板本身造成的术野干扰和操作干扰。

一种骨科医用3D打印锌基球形粉末及制备方法

NºPublicación:  CN120347202A 22/07/2025
Solicitante: 
广东省科学院新材料研究所
CN_120347202_PA

Resumen de: CN120347202A

本发明提供一种骨科医用3D打印锌基球形粉末及制备方法,属于金属粉末材料与制备技术领域,包括:制备符合成分要求的锌基金属熔体;将所述锌基金属熔体引流至高速旋转的圆盘中心,旋转加速后,分裂、成球、冷却、凝固,得到锌基球形粉末料;将所述锌基球形粉末料进行筛分,即得所述锌基球形粉末。通过选定锌基金属,并结合改进后的旋转圆盘,制备出高品质骨科医用3D打印锌基球形粉末,所制备出的3D打印锌基球形粉末空心粉率降低至1%以内,粉末球形度高,粉末粒径的D90与D10之差小于10µm,粉末利用率可达90%以上。

生物墨水制造装置

NºPublicación:  CN120359055A 22/07/2025
Solicitante: 
浦项控股股份有限公司浦项产业科学研究院浦项工科大学校产学协力团
CN_120359055_PA

Resumen de: WO2024128661A1

A bioink manufacturing device is provided. The bioink manufacturing device according to the invention includes: a reaction container for reacting a decellularized xenogeneic organ tissue with an inkification solution, a bioink liquefaction unit for stirring and crushing the decellularized xenogeneic organ tissue to liquefy same into bioink, and a bioink discharge unit for discharging the liquefied bioink outside of the reaction container.

一种时空间声学超材料贴片及其制备方法与应用

NºPublicación:  CN120346464A 22/07/2025
Solicitante: 
南京鼓楼医院
CN_120346464_PA

Resumen de: CN120346464A

本发明公开了一种时空间声学超材料贴片及其制备方法与应用,包括自下而上依次设置的压电基底、聚焦声波换能器以及声学阻抗匹配层;所述的聚焦声波换能器为两对以上的叉指电极对,各叉指电极对能够通过交频信号各自激活并产生聚焦声场;所述的声学阻抗匹配层为通过光刻打印逐层光交联的微米尺度锥形结构阵列,能够实现声学传感器和组织的阻抗匹配。本发明利用多重叉指电极具有时空间聚焦超声能量的功能,而且声学阻抗匹配层可以更好的传递声波能量和装载各种治疗功能的活性物质,从而实现低温伤口的热、炎症、和愈合多重管理。这种基于声学超材料为基础的贴片具有多功能、数字化可控、精准治疗、方便可靠等优点。

3D打印金属植入物

NºPublicación:  CN223111858U 18/07/2025
Solicitante: 
绵阳市第三人民医院
CN_223111858_U

Resumen de: CN223111858U

本实用新型公开了3D打印金属植入物,包括植入物主体。本实用新型通过采用了顶部件、中部件、底部件,作业时,通过3D打印机可以分批次的将顶部件、中部件以及底部件进行3D生产出来,接着将生产出来的多组部件可以通过底部的限位环与顶部的定位槽进行对接就可以实现多组结构的初步连接操作,接着转动结构可以使得孔洞相互对齐,然后在孔洞中安装上紧固螺栓,通过紧固螺栓就可以实现多组结构的固定操作,由于构成植入物主体的结构采用模块化的设置,因此在生产过程中容错率大幅度提升,可以在某一部件出现不合格时针对性的进行替换生产,不需要整个结构进行重新生产,有效的提升了整体的使用灵活性以及实用性,具有生产容错率高、使用灵活的优点。

基于人工智能的髓腔固位冠制造方法、系统

NºPublicación:  CN120326941A 18/07/2025
Solicitante: 
苏州派克顿科技有限公司
CN_120326941_PA

Resumen de: CN120326941A

本发明涉及牙冠制造技术领域,具体涉及基于人工智能的髓腔固位冠制造方法、系统,基于人工智能的髓腔固位冠制造方法包括:获取口腔CBCT影像与口扫模型;将口腔CBCT影像与口扫模型合成为合成模型;将合成模型输入训练后的AI模型,由AI模型基于合成模型生成髓腔固位冠模型;对髓腔固位冠模型做模拟受力测试,当髓腔固位冠模型的任意区域的应力大于预定值时,重新生成髓腔固位冠模型;对模拟受力测试合格的髓腔固位冠模型做模拟试戴测试;根据模拟试戴测试的结果调整髓腔固位冠模型;将调整后的髓腔固位冠模型输入打印装置并打印生成半成品髓腔固位冠;对半成品髓腔固位冠进行固化处理,生成成品髓腔固位冠。本申请提高了患者体验。

一种FARSs的数字化设计及制作方法及FARSs

NºPublicación:  CN120324131A 18/07/2025
Solicitante: 
同济大学
CN_120324131_A

Resumen de: CN120324131A

本发明公开了一种FARSs的数字化设计及制作方法及FARSs,该方法包括:获取使用者静态的上下颌牙列数字化三维模型、颌骨数字化三维模型及下颌动态运动数据,并在CAD/CAM软件内进行拟合,以构建使用者的动态VDP模型;基于使用者的动态VDP模型,确定使用者的治疗颌位,并导出对应于各治疗颌位的数字化三维牙列模型;依据所导出的各治疗颌位对应的数字化三维牙列模型,在CAD/CAM软件内中完成牙合面具有解剖形态的FARSs的个性化设计;根据个性化FARSs的设计数据,使用3D打印技术一次性完成FARSs的制造。本发明制作的FARSs通过全数字化流程制作,相比传统前伸再定位咬合板,个性化位置精度高,贴合性好,舒适度高,可以改善咀嚼功能;其次,序列治疗降低治疗难度、减少患者复诊次数。

纳米羟基磷灰石/聚酰胺66复合材料的成型方法及应用

NºPublicación:  CN120326930A 18/07/2025
Solicitante: 
常德市第一人民医院
CN_120326930_PA

Resumen de: CN120326930A

本发明公开了纳米羟基磷灰石/聚酰胺66复合材料的成型方法及应用,其中,纳米羟基磷灰石/聚酰胺66复合材料的成型方法,包括:成型,采用熔融沉积成型的挤出式3D打印机对含纳米羟基磷灰石/聚酰胺66复合材料的料浆进行3D打印成型,得到打印件;后处理,对所述打印件依次进行干燥和退火,得到纳米羟基磷灰石/聚酰胺66复合材料的成型件。本申请利用3D打印可基于患者CT数据的三维重建技术可定制椎体假体形态,实现与复杂解剖结构的精确匹配,避免标准化椎体假体的局限性;还能够精确设计孔隙结构,而羟基磷灰石本身具备微观孔隙结构(<10μm),从而使产品具备多级孔隙结构,有利于加速骨整合。

一种具有活性的骨缺损修复材料及其制备方法

NºPublicación:  CN120324678A 18/07/2025
Solicitante: 
中科之光生物科技(河北省)有限公司
CN_120324678_PA

Resumen de: CN120324678A

本发明公开了一种具有活性的骨缺损修复材料及其制备方法。所述骨缺损修复材料由动物来源提取的胶原蛋白、煅烧骨基质及骨形态发生蛋白复合微球复合,通过光固化3D打印技术成型制成。本发明从仿生角度出发,拟以胶原蛋白作为框架材料,以免疫原性低的煅烧骨基质作为硬质材料增强材料力学支持,并辅以骨形态发生蛋白复合微球协同作用,长效引导未分化间充质干细胞向特定方向发展。该活性骨缺损修复材料,植入骨缺损部位后,为细胞提供一个利于细胞粘附和增殖微观环境,同时骨形成发生蛋白的缓慢释放,能够长效作用于骨缺损部位,有效地推动成骨细胞分化成熟的过程,促进骨缺损部位的骨修复。

ORTHODONTIC TEETH-STRAIGHTENER MADE OF SHAPE-MEMORY POLYMERS, AND METHOD FOR THE PRODUCTION OF SAME

NºPublicación:  US2025228647A1 17/07/2025
Solicitante: 
FRAUNHOFER GES ZUR FOERDERUNG DER ANGWANDTEN FORSCHUNG E V [DE]
HEINRICH HEINE UNIV DUESSELDORF [DE]
Fraunhofer-Gesellschaft zur Foerderung der Angwandten Forschung e.V,
Heinrich-Heine-Universitaet Duesseldorf
DE_102022125583_PA

Resumen de: US2025228647A1

An orthodontic teeth-straightener, comprising a splint element which contains, or is entirely made from, a thermoplastic polyurethane having shape-memory properties. The thermoplastic polyurethane having shape-memory properties is selected from the group of polyether polyurethanes and contains hard segments which contain polyurethane units that have been obtained by polyaddition of the isocyanate groups of a diisocyanate to the hydroxyl groups of a diol acting as a chain extender, thereby forming urethane groups. The polyether polyurethane also contains soft segments, which contain, or are entirely made from, polyether units in the form of polyalkylene glycols, wherein the polyether units are bonded to isocyanate end groups of the diisocyanate of the hard segments, thereby forming urethane groups with the hard segments. The thermoplastic polyether polyurethane is both thermo-responsive and water-responsive and thus gives the splint element dual-stimuli responsive shape-memory properties.

BIOMANUFACTURING SYSTEM, METHOD, AND 3D BIOPRINTING HARDWARE IN A REDUCED GRAVITY ENVIRONMENT

NºPublicación:  US2025230391A1 17/07/2025
Solicitante: 
REDWIRE SPACE TECH INC [US]
REDWIRE SPACE TECHNOLOGIES, INC

Resumen de: US2025230391A1

A method, apparatus, and system are provided for the printing and maturation of living tissue in an Earth-referenced reduced gravity environment such as that found on a spacecraft or on other celestial bodies. The printing may be three-dimensional structures. The printed structures may be manufactured from low viscosity biomaterials.

AUTOMATED ORTHODONTIC ALIGNER MANUFACTURING AND ASSESSMENT

NºPublicación:  US2025229463A1 17/07/2025
Solicitante: 
ALIGN TECH INC [US]
Align Technology, Inc
CN_118369066_PA

Resumen de: US2025229463A1

A manufacturing system comprises a holder, a robot arm, a press and a laser. The holder is configured to receive a feature of a dental appliance and to hold the dental appliance by clamping the feature of the dental appliance, wherein the holder holds the feature of the dental appliance at a reference position. The robot arm is configured to retrieve an object and to place the object against the feature at the reference position. The press is configured to apply pressure to press the object against the feature of the dental appliance while the dental appliance is held by the holder. The laser is configured to expose an interface of the dental appliance and the object to coherent light to weld the object to the feature of the dental appliance while the press presses the object against the feature of the dental appliance.

Surgical Implant And Methods Of Additive Manufacturing

NºPublicación:  US2025228594A1 17/07/2025
Solicitante: 
K2M INC [US]
K2M, Inc
US_2023293208_PA

Resumen de: US2025228594A1

A method of manufacturing a surgical implant includes simultaneously forming a first component and a second component of the surgical implant. Formation of the first and second components includes depositing a first quantity of material to a building platform and fusing the first quantity of material to form a first layer of the first and second components. The method of manufacturing also includes depositing a second quantity of material over the first layer of the first and second components and fusing the second quantity of material to form a second layer of the first and second components. The surgical implant is fully assembled upon the completion of the formation of the first and second components.

LIQUID WITH PATTERN AND PRODUCTION METHOD FOR SAME

NºPublicación:  AU2023419073A1 17/07/2025
Solicitante: 
SUNTORY HOLDINGS LTD
SUNTORY HOLDINGS LIMITED
AU_2023419073_A1

Resumen de: AU2023419073A1

The purpose of the present invention is to provide: a liquid with a pattern, said liquid including a pattern that can produce, in a liquid matrix, a sensation such as a color, a flavor, a texture, or a tactile sensation, said pattern having good stability; and a method for producing a liquid with a pattern which makes it possible to stably form a pattern in a liquid matrix. The present invention relates to, for example, a liquid with a pattern, said liquid including, in a liquid matrix, a pattern formed by microparticles and/or a pigment, wherein the liquid matrix is pseudoplastic fluid and is accommodated in a container.

光硬化性組成物及び歯科用製品

NºPublicación:  JP2025107275A 17/07/2025
Solicitante: 
三井化学株式会社
JP_2025107275_PA

Resumen de: JP2023143923A

To provide a photocurable composition which can yield a cured product with the suppressed formation of cracks and breaks and excellent handleability.SOLUTION: A photocurable composition includes a (meth)acrylic monomer component and a photopolymerization initiator, wherein the adhesive force of its cured product is less than or equal to 1.5 N, and the rupture elongation of the cured product is greater than or equal to 20%.SELECTED DRAWING: Figure 1

光開始剤、それを含むバイオインク及びハイドロゲルの製造方法

NºPublicación:  JP2025107169A 17/07/2025
Solicitante: 
プサンナショナルユニバーシティインダストリー-ユニバーシティコーポレーションファウンデーション
JP_2025107169_PA

Resumen de: US2025222169A1

The present disclosure relates to a photoinitiator, a bioink including the same, and a method of manufacturing a hydrogel. According to the present disclosure, the photoinitiator of the present disclosure may have water solubility, high molar extinction coefficient, and low cytotoxicity. In addition, the method of manufacturing a hydrogel of the present disclosure may have high cell viability by increasing 3D printing efficiency due to a fast photo-curing rate.

3D PRINTED ARTIFICIAL BILE DUCTS AND MANUFACTURING METHOD THEREOF

NºPublicación:  US2025229006A1 17/07/2025
Solicitante: 
IUCF HYU INDUSTRY UNIV COOPERATION FOUNDATION HANYANG UNIV [KR]
PASAN NATIONAL UNIV INDUSTRY UNIV COOPERATION FOUNDATION [KR]
IUCF HYU INDUSTRY UNIV COOPEATION FOUNDATION HANYANG UNIV [KR]
IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY),
PASAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION,
IUCF-HYU (INDUSTRY-UNIVERSITY COOPEATION FOUNDATION HANYANG UNIVERSITY)

Resumen de: US2025229006A1

The present invention relates to an artificial bile duct comprising ursodeoxycholic acid (UDCA), and due to comprising UDCA, the artificial bile duct of the present invention is effective in improving differentiation into cholangiocytes and preventing formation of bile stones.

REMOVABLE DENTAL APPLIANCE INCLUDING SPRING MEMBER AND COMPUTER METHOD OF DESIGNING SAID APPLIANCE

NºPublicación:  EP4585185A2 16/07/2025
Solicitante: 
SOLVENTUM INTELLECTUAL PROPERTIES COMPANY [US]
Solventum Intellectual Properties Company
EP_4585185_PA

Resumen de: EP4585185A2

The present invention relates to a method comprising forming a model of dental anatomy of a patient; and forming, based on the model, a removable dental appliance. The dental appliance comprises an appliance body configured to at least partially surround a plurality of teeth of a dental arch of a patient. The appliance body comprisies a unitary material defining a shell shaped to receive at least one tooth of the patient and a spring member integrally formed with the shell. The spring member is configured to receive an attachment, wherein the attachment is configured to affix to the at least one tooth, and wherein the spring member is configured to apply a spring force to the attachment to cause at least one of a rotation, a translation, a tipping, a torqueing, an extrusion, or an intrusion of the at least one tooth toward a desired position of the tooth when the removable dental appliance is worn by the patient.

フィルム製剤の製造方法及びフィルム製剤の製造システム

NºPublicación:  JP2025106637A 16/07/2025
Solicitante: 
学校法人明治薬科大学
JP_2025106637_PA

Resumen de: WO2023234310A1

This production method for a film preparation comprises: (1) a step for discharging a solution containing at least one pharmaceutical active ingredient from a print head to print the solution onto a soluble substrate film, the pharmaceutical active ingredient being printed onto the soluble substrate film so that the film includes a dose by which a desired effect is exhibited upon administration to a subject. The printed soluble substrate film can be formulated as a drug delivery system selected from a group including an injectable agent, a suppository, and a transdermal patch. The present invention also provides a production system for a film preparation, the system being for implementing the method.

TRANSFER APPARATUS FOR ORTHODONTIC APPLIANCES AND RELATED METHODS OF MANUFACTURING

NºPublicación:  EP4584089A1 16/07/2025
Solicitante: 
SOLVENTUM INTELLECTUAL PROPERTIES COMPANY [US]
Solventum Intellectual Properties Company
CN_119855708_PA

Resumen de: CN119855708A

A method of manufacturing a transfer device includes providing a physical physical model having a shape corresponding to a positive shape of a patient's dental arch and one or more stent assemblies each including a lifting mechanism body releasably connectable to an orthodontic appliance. A transfer device may be formed over the physical entity model, wherein a transfer denture represents a negative replica of at least a portion of the entity model. The transfer device may be used to place the appliance on a patient's dental arch, after which the appliance may be detached from the lifting mechanism body and bonded to the associated tooth.

REMOVABLE DENTAL APPLIANCE INCLUDING SPRING MEMBER AND COMPUTER METHOD OF DESIGNING SAID APPLIANCE

NºPublicación:  EP4585184A2 16/07/2025
Solicitante: 
SOLVENTUM INTELLECTUAL PROPERTIES COMPANY [US]
Solventum Intellectual Properties Company
EP_4585184_PA

Resumen de: EP4585184A2

The present invention relates to a system comprising an ordered set of removable dental appliances configured to reposition one or more teeth of a patient. Each removable dental appliance in the set of removable dental appliances comprises an appliance body configured to at least partially surround a plurality of teeth of a dental arch of a patient. The appliance body comprises a unitary material defining a shell shaped to receive at least one tooth of the patient and a spring member integrally formed with the shell, wherein the spring member is configured to receive an attachment. The attachment is configured to affix to the at least one tooth. The spring member is configured to apply a spring force to the attachment to cause at least one of a rotation, a translation, a tipping, a torqueing, an extrusion, or an intrusion of the at least one tooth toward a desired position of the tooth when the removable dental appliance is worn by the patient.

一种悬空设计的3D打印脑部穿刺导板

Nº publicación: CN223095603U 15/07/2025

Solicitante:

自贡市第三人民医院

CN_223095603_U

Resumen de: CN223095603U

本实用新型涉及医用辅助器械,一种悬空设计的3D打印脑部穿刺导板,包括导板本体;导板本体包括与患者的骨性生理特征相适配的眉弓固定曲面和鼻根固定曲面,鼻根固定曲面由眉弓固定曲面的中段下侧朝下延伸形成,导板本体整体呈T型;导板本体还包括鼻头固定曲面和鼻侧悬伸曲面;鼻头固定曲面由鼻根固定曲面的下部朝下延伸形成,且能够包覆在患者鼻头上;鼻头固定曲面的一侧朝左/右延伸形成有鼻侧悬伸曲面;本实用新型通过眉弓固定曲面、鼻根固定曲面、鼻头固定曲面等进行多点固定,多点固定的形式使得整体的固定更加的稳定,相较传统的简单通过皮肤贴附固定的方式而言,不易产生位移,能够保证穿刺导向的精准性,防止体表组织移动造成的干扰。

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