Alerta

APPARATUS FOR PRODUCING TABLETS

Absstract of: WO2025195853A1

The invention relates to an apparatus (1) for producing tablets (2), wherein the apparatus (1) comprises a precursor material production device (3) and an additive manufacturing device (4), wherein the precursor material production device (3) is designed to coat granulate particles (6) containing a medicament (5) with a coating agent (8) comprising a thermoplastic material (7) in order to produce precursor material particles (9), and wherein the additive manufacturing device (4) is designed to produce tablets (2) from a powdered precursor material (10) comprising a plurality of precursor material particles (9) by selective laser sintering.

OBLIQUE-INCIDENT-BODY-WAVE-ASSISTED ULTRA-HIGH-CELL-DENSITY MULTICELLULAR TISSUE LIFTING BIOPRINTING DEVICE AND PRINTING METHOD THEREFOR

Absstract of: WO2025194541A1

The present invention relates to the technical field of medical manufacturing. Disclosed are an oblique-incident-body-wave- assisted ultra-high-cell-density multicellular tissue lifting bioprinting device and a printing method therefor, the bioprinting device comprising a printing liquid tank, a printing platform, a light source and an oblique incident body wave chip, wherein the printing liquid tank contains a printing liquid which is a mixture of cells and a photocurable bio-ink; the printing platform is arranged horizontally and extends into the printing liquid tank to come into contact with the printing liquid; the printing platform can be raised or lowered; the light source is arranged below the printing liquid tank, and light is incident into the printing liquid tank; the oblique incident body wave chip is a piezoelectric transducer arranged obliquely; and the piezoelectric transducer is arranged below the printing liquid tank and tilted relative to a horizontal plane so as to generate an oblique incident body wave acoustic field in the printing liquid. The present invention can realize large-volume three-dimensional printing of a biomimetic tissue model with an ultra-high-cell-density and multicellular structure, and has the advantages of being ultra fast, having a large volume, and having an adjustable cell concentration and a simple liquid-exchange structure.

CERAMIC PROCESSING FOR THE DIRECT MANUFACTURE OF CUSTOMIZED LABIAL AND LINGUAL ORTHODONTIC BRACKETS

Absstract of: US2025298391A1

A method of manufacturing customized ceramic labial/lingual orthodontic brackets by digital light processing, said method comprises measuring dentition data of a profile of teeth of a patient, wherein measuring dentition data is performed using a CT scanner or intra-oral scanner, based on the dentition data, creating a three dimensional computer-assisted design (3D CAD) model of the patient's teeth using reverse engineering, and saving the 3D CAD model on a computer, designing a 3D CAD bracket structure model for a single labial or lingual bracket structure, importing the 3D CAD bracket structure model into a Digital Light Processing (DLP) machine, directly producing the bracket by layer manufacturing.

EQUINE NASOGASTRIC TUBE MODEL AND RELATED METHODS

Absstract of: US2025299602A1

Systems and associated method of fabrication of anatomically accurate animal training models can comprise fabricating at least one inverse anatomical feature representative of an anatomical feature in an animal's head, forming a mold of the animal's head, connecting the at least one inverse anatomical feature in the mold of the animal's head, filling the mold of the animal's head with a filling material, and removing the cast head from the mold.

3D PRINTING TRANSPARENT BIOINK FORMULATION

Absstract of: US2025295837A1

Bioink comprising modified fibers of MFC with a diameter of about 100-400 nm.

RADIATION-CURABLE COMPOSITION FOR USE IN A RAPID PROTOTYPING PROCESS OR A RAPID MANUFACTURING PROCESS

Absstract of: US2025297044A1

Polymerizable, radiation-curable compositions are provided and comprise (i) monomers and (ii) at least one further component, wherein the (i) monomers comprise (a) at least one urethane (meth)acrylate that is at least difunctional, (b) at least one monofunctional acrylate having an alicyclic group and/or at least one monofunctional methacrylate having an alicyclic group, and (ii) the at least one further component comprises (c) at least one photoinitiator for the UV and/or visible range or a photoinitiator system for the UV and/or visible range. The compositions are usable for producing, via a rapid prototyping, manufacturing, or tooling process, dental prosthetic parts, orthopaedic instruments, or dental pre-forms that have a flexural strength of greater than or equal to 75 MPa, a modulus of elasticity of greater than or equal to 2600 MPa, and/or a water absorption of less than 45 μg/mm3.

SURGICAL CLAMP

Absstract of: AU2024235637A1

A surgical clamp for providing a stable mechanical grasp and stabilisation of bone during an orthopaedic surgical procedure, comprising: a first arm comprising: an extended section comprising a mount at the distal end thereof; and a first jaw portion located at the distal end of the first arm; a second arm comprising: a fastening platform located at the proximal end of the second arm; and a second jaw portion located at the distal end of the second arm; engagement means comprising a bolt to engage the first arm with the second arm about a pivot point formed by the engagement means to provide relative rotation of the first and second arms between: an open configuration whereby first jaw portion and second jaw portion are urged apart; and a clamped configuration whereby first jaw portion and second jaw portion are urged into clamping engagement with the patient's bone in use during the surgical procedure; a fastening component comprising a fastening bolt and a fastening nut, adapted to engage the first and second arm into a locked clamped configuration about the bone of a patient during the surgical procedure; and a handle adapted to be gripped by a surgical assistance for stabilisation of the patient's joint or bone during the surgical procedure.

Impact Resistant Material

Absstract of: US2025297834A1

The current disclosure is directed to an impact resistant material made from a novel melanin composite. It has been found that using these composites allows for the production of effective ballistic protection and blast containment materials.

MULTI-VALENT POLYMERIZABLE COMPOSITIONS AND METHODS OF PRODUCING AND USING THE SAME

Absstract of: US2025297052A1

The present disclosure provides photo-polymerizable components, photo-curable resins comprising one or more of such monomers, as well as polymeric materials formed from the photo-curable resins. Further provided herein are methods of producing the compositions and using the same for the fabrication of medical devices, such as orthodontic appliances.

3D PRINTED MATERIALS AND METHODS

Absstract of: US2025295839A1

Aspects of the present disclosure generally relate to 3D printed scaffolds for attaching a radionuclide and methods of use thereof. In some embodiments, 3D printed scaffolds comprising a first layer and/or a second layer, and a radionuclide, are provided. In some embodiments, methods for capturing a radionuclide using said 3D printed scaffolds, are provided. In some embodiments, methods of using 3D printed scaffolds with a radionuclide to capture a daughter radionuclide product at a location different than the 3D printed scaffold, are provided.

COLLAGEN-CONTAINING CURABLE FORMULATIONS

Absstract of: US2025295791A1

A conjugate made of collagen and a plurality of curable elastic moieties covalently attached thereto, a curable formulation (e.g., a bioink composition) that comprises the conjugate and additive manufacturing of a three-dimensional object which utilizes the curable formulation are provided. Also provided are methods/processes of additive manufacturing that employ collagen that feature a plurality of photocurable groups, in which the viscosity of a collagen-containing formulation is determined by manipulating an amount of the photoinitiator that is mixed with the collagen.

CHAOTIC PRINTING FOR THE PRODUCTION OF NON-FILAMENTOUS ARCHITECTURES

Absstract of: US2025296278A1

Disclosed are methods for preparing non-filamentous scaffolds (e.g., sheets) for cell or tissue culture. These methods can comprise providing at least a first printing composition (e.g., a bioink) and a second printing composition (e.g., a bioink or a fugitive ink); chaotic printing the first printing composition and the second printing composition to generate a microstructured precursor comprising a plurality of lamellar structures formed from the first printing composition and the second printing composition; extruding the microstructured precursor through a nozzle (e.g., a fan-shaped nozzle, a curved fan-shaped nozzle, or an annular nozzle) to produce a non-filamentous microstructured precursor; and curing the non-filamentous microstructured precursor to provide the non-filamentous scaffold for cell or tissue culture.

FUNCTIONALLY-DIVIDABLE ORODISPERSIVE DOSAGE FORM

Absstract of: US2025295593A1

A dividable tablet with a functional seam for functionally dividing the dividable tablet into substantially equivalent sub-dosage units along the functional seam. The functional seam is configured to subdivide the sub-dosage units into the same mass within a tolerance of about 3% or less, and typically of 1.0% or less. The functional seam is configured reduce the amount of lost material that separates from the divided sub-dosage units after division of the dividable tablet along the functional seam, to less than 3%, and typically less than 1.0%, and more typically less than 0.1% of the mass of the undivided dividable tablet.

ADJUSTABLE BRACE AND PROCESSES FOR MAKING AND USING SAME

Absstract of: US2025295513A1

An adjustable brace for stabilizing a body part of a patient and a method of fabricating such a brace is provided. In some embodiments, the adjustable brace comprises a first stabilizer having a first exterior surface, a first interior surface, a first thickness, and a plurality of first stabilizer guides; a second stabilizer comprising a second exterior surface, a second interior surface, a second thickness, and a plurality of second stabilizer guides; and at least one flexible lacing member extending along the first and second stabilizer guides, wherein the flexible lacing member adjustably secures the first stabilizer to the second stabilizer. Additional embodiments further include a closure mechanism to assist in the flexible lacing member adjustment.

Medical device based on bioceramics, its use as a synthetic bone graft and process for the preparation thereof

Absstract of: GB2639318A

The present invention relates to a medical device manufactured using the additive manufacturing process (3D printing). It is a medical device used preferably as a bone graft composed of a porous structure based on bioceramics based on β-tricalcium phosphate (β-TCP) or hydroxyapatite, which may or not contain nanostructures in its composition, for example: carbon nanostructures (graphene, graphene oxide, reduced graphene oxide, carbon nanotubes, etc.) and, in preferred embodiments, stem cells and polymeric membrane. Also, the present invention relates to the use of this device as a bone graft and the process of preparing this device.

ASSEMBLY FOR CARRYING A DENTAL PROSTHESIS AND A METHOD OF MANUFACTURING THE SAME

Absstract of: WO2024104515A1

The object of the invention is an assembly for carrying a dental prosthesis and a method of manufacturing the same, wherein the assembly for carrying a dental prosthesis comprises a dental implant (1 ), a fixation screw (2), and a pillar (3) for fixing the dental prosthesis, where the pillar (3) comprises a first end (4) of the pillar, a second end (5) of the pillar opposite the first end (4) of the pillar, and a cavity (6) of the pillar, wherein the cavity (6) of the pillar opens at both the first and second ends (4,5) of the pillar and the first end (4) of the pillar is adjacent to the dental implant (1 ), wherein at least a part of the fixation screw (2) is located in the cavity (6) of the pillar and the fixation screw (2) is connected to the dental implant (1 ), wherein the cavity (6) of the pillar comprises a first side (7) of the cavity comprising a first section (8) of the cavity and a second side (9) of the cavity comprising a second section (10) of the cavity, wherein the first side (7) of the cavity is located closer to the first end (4) of the pillar than the second side (9) of the cavity and the cross-section of the first section (8) of the cavity is larger than the cross-section of the second section (10) of the cavity, wherein the fixation screw (2) comprises a head (11 ) of the fixation screw that is located in the first side (7) of the cavity.

FUNCTIONALLY-DIVIDABLE ORODISPERSIVE DOSAGE FORM

Absstract of: WO2024108084A1

A dividable tablet with a functional seam for functionally dividing the dividable tablet into substantially equivalent sub-dosage units along the functional seam. The functional seam is configured to subdivide the sub-dosage units into the same mass within a tolerance of about 3% or less, and typically of 1.0% or less. The functional seam is configured reduce the amount of lost material that separates from the divided sub-dosage units after divi sion of the dividable tablet along the functional seam, to less than 3%, and typically less than 1.0%, and more typically less than 0.1% of the mass of the undivided dividable tablet.

一种种植基台的牙冠批量打印装置及方法

Absstract of: CN120680724A

本发明提供了一种种植基台的牙冠批量打印装置及方法包括：利用牙龈形态数据库对患者牙龈采样数据进行深度优化，确定患者的基台排布特征并确定所述患者的基台打印数据，根据所述患者的已提需求和所述基台排布特征创建所述患者的若干种牙冠形态，并构建每一所述牙冠形态对应的牙冠打印数据，根据所述患者的面部数据分别模拟每一所述牙冠打印数据对应的打印效果，根据指令选取目标牙冠打印数据，根据所述基台打印数据和所述目标牙冠打印数据分别打印所述患者的基台和牙冠，根据患者的需求和实际取模结果自动调整打印设备的激光功率和打印预备工作，可以实现牙冠和基台的批量打印或个性化打印，提高了打印的效率，确保了打印成品的质量。

一种氧化锌-氧化铝陶瓷骨修复支架的制备方法

Absstract of: CN120682021A

本发明涉及生物医学材料的技术领域，公开了一种氧化锌‑氧化铝陶瓷骨修复支架的制备方法；首先按照比例称取氧化铝造粒粉和酚醛树脂粉体，混合氧化铝造粒粉和酚醛树脂粉体，得到获得3D打印复合粉体；其次，将3D打印复合粉体通过选择性激光烧结设备，制备得到氧化铝陶瓷坯体；将氧化铝陶瓷坯体进行干燥，得到干燥后的陶瓷坯体，并将干燥后的陶瓷坯体进行脱脂和烧结处理，冷却得到氧化铝预成型体；最后，使用纳米氧化锌溶胶对所述氧化铝预成型体进行真空压力浸渗，并引入动麦优化算法对真空压力浸渗参数进行优化，得到氧化锌‑氧化铝陶瓷骨修复支架；本发明通过制备工艺和智能优化工艺参数得到氧化锌‑氧化铝陶瓷骨修复支架，方法客观准确。

使用三维模型制造物体的方法和系统

Absstract of: CN120680723A

本申请涉及一种三维模型制造物体的方法和系统。上述方法包括：获取多个待打印的三维模型，三维模型包括模型关联信息，根据模型关联信息将各三维模型存储至一个或多个存储单元中，从指定存储单元中自动抓取至少一个目标三维模型，对目标三维模型进行排版处理，得到排版结果，基于排版结果，对目标三维模型进行三维打印。采用本方法能够能够在三维模型文件设计完成后，分类存储，自动抓取数据，自动完成前处理，并自动下发至三维打印设备进行三维打印，全程无需人工任何操作，提高三维模型的打印效率。

全口义齿及全流程数字化的全口义齿制作方法

Absstract of: CN120678548A

本发明公开全口义齿及全流程数字化的全口义齿制作方法。本发明以光学印模替代传统印模，电子运动面弓+下颌运动轨迹描记替代机械面弓+哥特式弓描记，结合语音法显示的下颌轨迹特征，替代传统的颌位记录，技术敏感性更低，颌位关系记录更精准，在口扫后过软件预排牙和电子面弓直接生成咬合方案，省去蜡型试戴、传统的颌位记录等中间步骤，且本申请采用数字化制造减少手工操作，三维打印/切削技术直接输出义齿，省去装盒、煮牙、打磨等繁琐工序，制作周期大大缩短，往后二次复制或再制作时间及适应时间大大等缩短，并为全口种植咬合重建颌位提供数字化解决方案，更利于数智数据的开发、整合等。

医用组织包裹物

Absstract of: AU2023370241A1

The invention relates to the field of medical tissue wraps for internal anatomical structures as well as a use and a method of treating a nerve lesion using such medical tissue wraps. In particular, the invention relates to medical tissue wraps for neural tissue supporting the repair of peripheral nerve lesions by facilitating secure application of the medical tissue wrap. Accordingly, a medical tissue wrap (10) for an internal anatomical structure of a mammal is suggested, wherein the medical tissue wrap (10) is formed by a coiled wall (12) having a circumferential inner end portion (20) and a circumferential outer end portion (22) extending around and overlapping the circumferential inner end portion (20). The wall (12) thereby defines a longitudinal through-hole (16) for accommodating a portion of the anatomical structure. According to one aspect of the invention, the circumferential outer end portion (22) is radially spaced-apart from the circumferential inner end portion (20) by a discontinuous spacing in the circumferential direction. According to a further aspect, the tissue wrap comprises a structural outer surface modification at opposing longitudinal end portions of its wall.

用于3D打印的金属粉末

Absstract of: US2024123495A1

A method of using a metal powder in an additive manufacturing process. The method includes providing the metal powder, and using the metal powder in the additive manufacturing process. The metal powder is a metal which is selected from tantalum and impurities, titanium and impurities, niobium and impurities, an alloy of tantalum, niobium and impurities, an alloy of titanium, niobium and impurities, and an alloy of tantalum, titanium, niobium and impurities. Particles of the metal powder have a dendritic microstructure. Particles of the metal powder have an average aspect ratio ΨA of from 0.7 to 1, where ΨA=XFeret min/XFeret max.

一种仿生甲虫骨架植入物的制备方法

Absstract of: CN120680013A

本发明公开了一种仿生甲虫骨架植入物的制备方法，属于股骨植入领域。本发明创新性地将甲虫鞘翅和角质层的仿生结构特征相结合，通过仿生结构设计的方法有效提升了多孔镍钛合金结构植入体的力学强度和结构稳定性，成功解决了传统股骨金属植入物长期存在的应力屏蔽效应问题，采用选择性激光熔化（SLM）技术制备出的多孔镍钛合金仿生骨架结构，其不仅具有良好的力学适配性，避免了植入后与自然骨组织的排斥脱落反应，还能在室温环境下实现完全的形状记忆恢复功能，在医用骨科植入领域具备良好的应用前景。

一种基于FDM多材料3D打印的微电流面膜及其制备方法

Nº publicación: CN120678663A 23/09/2025

Applicant:

中山火炬职业技术学院

Absstract of: CN120678663A

本发明公开一种基于FDM多材料3D打印的微电流面膜及其制备方法，所述微电流面膜包括薄膜电池层、支撑层、活性成分层和吸附层，通过采用多层叠覆式结构设计，各层之间相互配合，由内而外依次设置，各层面积按照面部的弧度和轮廓逐渐递减，通过正金字塔型逐级递减的面积设计增强微电流面膜的贴合度，根据面部轮廓更好地贴合皮肤，减少对面部的拉扯和不适感。所述微电流面膜的制备方法，基于用户面部扫描数据，并通过多维特征融合分析，将获取的数据进行整合分析，使得建立的三维模型更为自然和贴切用户的实际面部，实现精确定制微电流面膜，提高微电流面膜的贴合度和舒适性；同时采用了FDM多材料3D打印技术，支持多材料的精确组合和功能集成，增强微电流面膜的功效性和安全性。