Alerta

WATER-SOLUBLE, BIOCOMPATIBLE, BIODEGRADABLE, 3D-PRINTABLE, AND RADIATION-CURABLE POLYMERIC PRODUCTS USED AS BIOINK

Absstract of: WO2025095908A1

This invention provides water-soluble, biocompatible, biodegradable, 3D-printable, and radiation-curable polymeric bioinks for tissue engineering and a variety of other biomedical applications. Synthesized using tailor-designed polyurethane and polyurea oligomers with controlled molecular weights and compositions, these bioinks offer optimized viscosity profiles for 3D printing and enhanced mechanical properties and structural stability. They are applicable in tissue engineering, wound healing, drug discovery, and other biomedical fields.

DEVICES AND METHODS FOR POSITIONING DENTAL AUXILIARIES ON TEETH

Absstract of: WO2025097054A1

Devices, methods, and systems for placing dental auxiliaries on teeth are provided. In some embodiments, for example, a dental auxiliary positioner for placing a dental auxiliary on a tooth includes: a registration element configured to receive a patient's tooth; and an auxiliary support coupled to the registration element and further coupled to an auxiliary, where the auxiliary support is configured to position the auxiliary against a surface of the tooth, and where the auxiliary support includes a frame extending at least partially around the auxiliary, one or more struts coupling the auxiliary to the frame, and a flexible bridge coupling the frame to the registration element, where the flexible bridge is configured to bend in one or more directions relative to the tooth to adjust the position of the auxiliary on the surface of the tooth.

CONTINUOUS ANALYTE MONITORING SYSTEM POWER CONSERVATION

Absstract of: EP4802999A2

0001 Disclosed are devices, systems and methods for power management in an electronics unit of a sensor device, e.g., such as in a continuous analyte sensor system. In some example embodiments, there is provided a method that includes monitoring, by a controller of a sensor electronics module, counts associated with signals received from a sensor device for a first period of time. The method also includes comparing a number of received counts with one or more benchmarked count thresholds, and determining whether to initiate an operational mode of the sensor electronics module based on the comparison. Related systems, methods, and articles of manufacture are also described.

METHOD FOR ADAPTING AN ORTHODONTIC APPLIANCE

Absstract of: EP4804205A2

0001 L'invention concerne un système d'adaptation d'un appareil orthodontique destiné à un patient, ledit système comportant les étapes suivantes : a) à un instant de paramétrage, détermination, par un premier professionnel de soins dentaires et spécifiquement pour ledit patient, de conditions pour une communication d'une information actualisée relative à la configuration de dentition du patient ; b) à un instant actualisé postérieur à l'instant de paramétrage, acquisition, au moyen d'un appareil d'acquisition et par le patient ou un proche du patient, d'une représentation extraorale d'au moins une partie des arcades dentaires du patient, dite « représentation actualisée », ladite représentation actualisée étant constituée d'un ensemble d'images et/ou d'un modèle numérique tridimensionnel ; c) analyse de ladite représentation actualisée, de manière à déterminer une information sur ladite configuration de dentition à l'instant actualisé, ou « information actualisée », l'information actualisée étant constituée d'un ensemble d'éléments d'information exprimant chacun un statut pour un objectif de traitement respectif, au regard de la représentation actualisée ; d) communication de l'information actualisée à au moins un deuxième professionnel de soins dentaires, dans les conditions déterminées à l'étape a), e) adaptation dudit appareil orthodontique en fonction de l'information actualisée communiquée à l'étape d).

FERTILITY PREDICTION FROM WEARABLE-BASED PHYSIOLOGICAL DATA

Absstract of: EP4802996A2

0001 Methods, systems, and devices for fertility prediction are described. A system may be configured to receive physiological data collected over a plurality of days, where the physiological data includes at least temperature data. Additionally, the system may be configured to determine a time series of temperature values taken over the plurality of days where the time series includes a plurality of menstrual cycles. The system may then determine a plurality of menstrual cycle length parameters associated with the menstrual cycles and determine a user fertility prediction based on the menstrual cycle length parameters. The system may generate a message for display on a graphical user interface that indicates the determined user fertility prediction.

PIEZOELECTRIC COATED IMPLANTS AND METHODS OF USING PIEZOELECTRIC COATED IMPLANTS TO REPAIR BONE STRUCTURES

Absstract of: EP4803311A2

0001 Various embodiments of implant systems and related apparatus, and methods of operating the same are described herein. In various embodiments, an implant for interfacing with a bone structure includes a web structure, including a space truss, configured to interface with human bone tissue. The space truss includes two or more planar truss units having a plurality of struts joined at nodes. Implants are coated with, or have struts formed from, a piezoelectric material to enhance bone growth around and through the implant.

RECTANGULAR/ELONGATED ARRAY IN ULTRASOUND IMAGING WITH USER GUIDANCE FOR HIGHER RESOLUTION ANATOMICAL VIEW PLANES

Absstract of: EP4803012A1

The present disclosure may include devices, systems, apparatuses, and methods for capturing improved 2D images of desired view planes. For example, an apparatus is disclosed that includes a rectangular ultrasound array and a processor configured for communication therewith. The processor may be configured to: control the rectangular ultrasound array to obtain 3D ultrasound data of an anatomy of a patient while the rectangular ultrasound array is in a first pose; determine a location of a 2D view plane of the anatomy within a 3D model of the anatomy based on at least the 3D ultrasound data; determine, for the 2D view plane, a first scan angle associated with the first pose of the rectangular ultrasound array; determine, for the first scan angle, a first image quality; and output a screen display comprising the location of the 2D view plane, the first scan angle, and/or the first imaging quality.

一种具有仿生多孔结构的人工血管及其制备方法

Absstract of: CN122701932A

本发明提供了一种具有仿生多孔结构的人工血管，所述的人工血管的外表面具有多个凹陷状微孔，所述人工血管的基材为聚(巯丙基甲基硅氧烷‑二甲基硅氧烷)和乙烯端聚二甲基硅氧烷。本发明还提供了上述具有仿生多孔结构的人工血管的制备方法，以聚(巯丙基甲基硅氧烷‑二甲基硅氧烷)和乙烯端聚二甲基硅氧烷为基材，随后依次加入光引发剂和致孔剂并混匀，利用SLA光固化技术将上述混合材料打印成型，最后加以清洗和浸泡以去除未固化材料并溶出聚乙二醇羧酸。本发明制备的具有仿生多孔结构的人工血管具有微米级或纳米级多孔网络，同时具备高精度、良好的力学匹配度和优异的生物相容性。

ユーザのために最適化された警告を提供するためのシステム及び方法

Absstract of: US2017311904A1

0001 Systems and methods are disclosed that provide smart alerts to users, e.g., alerts to users about diabetic states that are only provided when it makes sense to do so, e.g., when the system can predict or estimate that the user is not already cognitively aware of their current condition, e.g., particularly where the current condition is a diabetic state warranting attention. In this way, the alert or alarm is personalized and made particularly effective for that user. Such systems and methods still alert the user when action is necessary, e.g., a bolus or temporary basal rate change, or provide a response to a missed bolus or a need for correction, but do not alert when action is unnecessary, e.g., if the user is already estimated or predicted to be cognitively aware of the diabetic state warranting attention, or if corrective action was already taken.

治療計画に個別化された歯科矯正アライナーセットのためのプロセスおよびシステム

Absstract of: EP4512363A1

0001 The present invention relates to a process for the production of an orthodontic aligner set comprising at least two aligners of different aligner shell materials, wherein the process at least comprises the production steps of: a) providing at least two different physical dental models, wherein the dental models comprise a base plate and a teeth configuration thereon, wherein the teeth configuration defines at least a part of a patients present or future teeth configuration and each model comprises an individual identifier, wherein the identifier comprises information at least encoding for the specific patient and the aligner shell material; b) placing at least one of the physical dental models provided in step a) in a deep draw chamber; c) Reading the individual identifier on the physical dental model and presenting at least the encoded information with respect to the aligner shell material, wherein the reading is performed after step a) and before step d); d) Selecting the specific aligner shell material as represented by the encoded information in process step c); e) Placing the selected aligner shell material over the physical dental model, heating of the aligner shell material, wherein the heating is performed prior, during or after placing of the selected aligner shell material, and deep drawing the aligner shell material to the physical dental model in order to produce a single orthodontic aligner; f) Removing the dental model and the orthodontic aligner from th

单宁酸功能化的双网络水凝胶、其复合材料及3D打印软骨修复补片

Absstract of: CN122701936A

本发明公开了一种单宁酸功能化的双网络水凝胶、其与聚己内酯的复合材料及双喷头3D打印软骨修复补片。所述水凝胶由甲基丙烯酸明胶光交联第一网络和氧化葡聚糖席夫碱交联第二网络构成，并均匀分散有单宁酸，还可负载TGF‑β1、BMP‑2等生长因子。该水凝胶具有多孔结构，单宁酸的引入不仅赋予主动抗炎功能，还提高了水凝胶的力学性能，杨氏模量接近天然软骨。将水凝胶与PCL共混得到第一墨水（复合材料），另以纯水凝胶作为第二墨水，通过双喷头熔融沉积3D打印一体成型制备包含PCL支撑层和水凝胶活性层的仿生软骨补片。体内实验表明，该补片能够有效抑制IL‑1β、IL‑6、TNF‑α等炎症因子，显著促进软骨缺损修复。

情報提供装置、採血システム、情報提供方法およびプログラム

Absstract of: JP2026141823A

0001 【課題】ドナーの健康意識向上と採血リピートの促進とを図れる情報提供装置、採血システム、情報提供方法およびプログラムを提供する。 【解決手段】献血施設１００において、採血システム１０の情報提供装置１６は、採血装置１２のセンサユニット１４（１以上のセンサ）から出力される検出信号に基づいて、ドナーから採血される血液の状態を示す血液情報を取得する血液情報取得部３４と、血液情報に基づいてドナーの健康状態を判定する判定部４０と、判定部４０による判定の結果を示す情報をドナーに提供するための処理を実行する情報提供処理部４２と、を備える演算部３２を有する。 【選択図】図１

3D打印多孔钛合金产品的物理协同清洗方法、应用

Absstract of: CN122683138A

本发明公开了一种3D打印多孔钛合金产品的物理协同清洗方法、应用。该方法包括：S1、将待清洗产品浸入于超声波清洗装置中的清洗槽中，在20KHz～80KHz频率下超声处理5min～10min；S2、采用水流清洗单元，对超声处理后的待清洗产品的内部的孔隙进行物理冲刷；重复循环清洗流程至少两次，直至待清洗产品检测合格；循环清洗流程包括第一清洗流程和第二清洗流程，第一清洗流程为进行一次步骤S1的操作，第二清洗流程为进行一次步骤S2的操作。本发明通过超声处理与水流清洗单元协同，形成逐层深入的清洗效果，且该方法成本低廉且易于实施。

一种基于梯度蒸汽爆破的低分子量海藻酸钠制备方法及其应用

Absstract of: CN122685766A

本发明公开了一种低分子量海藻酸钠的制备方法、产品及其应用，属于生物高分子材料改性技术领域。本发明针对现有海藻酸钠降解法存在分子量分布宽、活性基团易破坏的技术问题，提供了一种"低温等离子体活化—梯度蒸汽爆破—负压重组"三级物理场耦合的制备方法。该方法包括：将海藻酸原料在含氧气氛中进行低温等离子体活化预处理；然后进行至少两级压力依次升高的梯度蒸汽爆破；再在负压环境下进行分子链重组；最后经中和、离心和干燥得到低分子量海藻酸钠。本发明制备的海藻酸钠重均分子量为20‑50kDa，分子量分布指数PDI≤1.5，1%水溶液透光率≥90%，可用于生物3D打印和药物控释载体。

一种基于先进生物打印技术辅助的声带修复装置

Absstract of: CN122681624A

一种基于先进生物打印技术辅助的声带修复装置，包括：成像定位部件，含内窥镜成像模块和三维重建处理器；手术操作部件，含声门暴露机构和象鼻式柔性机械臂，声门暴露机构暴露声门提供视野，机械臂高精度操作；生物修复部件，含微型打印头、相容性水凝胶、注射管及运动控制机构，实现声带重建与功能恢复。通过集成生物打印部件与成像定位部件，系统能够精确获取声带损伤区域的三维结构数据，并实现生物材料的毫米级精准沉积，使成像定位的毫米级精度、机械臂的微米级操作与生物材料的可控打印形成闭环反馈系统，提升声带修复的整体成功率，实现声带修复从"经验性操作"到"精准工程"的跨越，为声带功能障碍患者提供了更安全有效的治疗选择。

一种钛基超弹性形状记忆合金及其制备方法和应用

Absstract of: CN122687002A

本发明提供了一种钛基超弹性形状记忆合金及其制备方法和应用，属于合金技术领域。钛基超弹性形状记忆合金为TiMAlX合金，按照原子百分比计，M：29~41%，Al：18~26%，X：0.9~5.1%；其余为Ti和不可避免的杂质；其中，M为Zr和/或Nb，X为Mo、Ni、Fe、V、Cr、Mn或Ta中的一种或几种。本发明的钛基超弹性形状记忆合金中，混合焓较负的Al元素的含量较高，而且添加了特定的X元素作为强β稳定元素，在室温下，合金主要为B2母相；在外加载荷作用下发生应力诱导马氏体相变，形成B19马氏体相，从而产生可恢复变形。

具有集成读出的传感器阵列

Absstract of: TW202532824A

A deformable sensor array may include a plurality of sensors and a flexible substrate. Each sensor of the plurality of sensors may include a sensor die to generate an analog signal and an converter die to perform analog-to-digital conversion (ADC) of the analog signal to generate a digital output. The flexible substrate may include electrical interconnect coupled with the plurality of sensors, and strain relief cutouts between sensors of the plurality of sensors and between the electrical interconnect, to enable deformation of the plurality of sensors. Other aspects are also described and claimed.

一种3D打印碳纤维复合儿童下肢矫形器及其制备方法

Absstract of: CN122681633A

本发明涉及矫形器技术领域，公开了一种3D打印碳纤维复合儿童下肢矫形器及其制备方法，包括基底和侧连接架，基底和侧连接架采用3d打印一体成型设置，基底和侧连接架的外壁均粘接有碳纤维强化布，3粘接在基底、侧连接架的外壁后形成完整的矫形器，矫形器为贴合儿童下肢畸形轮廓的一体化薄壁壳体结构，本发明通过设置有采用薄壁3d打印基底加碳纤维布覆膜复合结构，摒弃传统矫形器厚壁补强的方式，基底壳体超薄设计，碳纤维层轻量化强化，整体厚度大幅降低，重量较传统矫形器减轻百分之四十至百分之六十，同时结构强度、刚性、抗冲击性大幅提升，不易变形开裂，解决现有产品轻薄度与强度无法兼顾的行业痛点。

一种增材制造用模型树脂及其制备方法和在3D打印制备牙科模型中的应用

Absstract of: CN122685815A

本发明涉及高分子材料领域，具体而言，涉及一种增材制造用模型树脂及其制备方法和在3D打印制备牙科模型中的应用,按质量份数计，包括以下原料：乙氧化双酚A二甲基丙烯酸酯35‑42份、三乙二醇二甲基丙烯酸酯35‑50份、脂肪族聚氨酯丙烯酸甲酯10‑20份、苯基双(2,4,6三甲基苯甲酰基)氧化膦1‑5份。将各原料加入到容器中，在避光条件下，先在1000‑1500 rpm转速下高速分散15‑30 min，再在300‑400 rpm转速下低速分散5‑15 min，即得到所述树脂。该树脂其粘度适中，3D打印性能优异，分散稳定性好，颜色均匀，表面固化性能和抗老化性能良好。

一种用于治疗糖尿病感染创面的负载碳点水凝胶微针及其制备方法

Absstract of: CN122681777A

本发明涉及一种用于治疗糖尿病感染创面的负载碳点水凝胶微针及其制备方法，首先制备功能化碳点QP‑CD‑2，随后基于所述QP‑CD‑2配置微针前驱液并进行光交联得到QP‑CD‑2@MNs。本发明制备的负载碳点水凝胶微针不仅具有高效的抗菌、抗氧化和抗炎活性，还具有重塑局部免疫微环境并促进创面快速且高质量再生的能力，具有良好的应用前景。

一种基于3D打印的聚二甲基硅氧烷异质双层引导骨再生膜及其制备方法

Absstract of: CN122682109A

本发明属于生物医用材料与组织工程领域，涉及一种基于3D打印的聚二甲基硅氧烷异质双层引导骨再生膜及其制备方法。所述方法包括采用一步法合成镓掺杂锌基金属有机框架材料GZM和铜掺杂锌基金属有机框架材料CZM并进一步进行二氧化硅包覆改性，然后将改性填料制备为复合墨水，通过3D打印得到具有双层异质结构的膜材料。本发明的双层引导骨再生膜具备良好的机械支撑能力与柔性适配能力以及良好的抗菌性能与促骨再生能力。

髋臼杯假体以及髋臼杯假体的制备方法

Absstract of: CN122681627A

本发明提供了一种髋臼杯假体以及髋臼杯假体的制备方法，其中，髋臼杯假体包括：金属杯主体，具有内腔以及与内腔连通的开口，开口用于使关节柄假体的球头伸入至内腔内；陶瓷涂层，覆盖在内腔的内壁面上；羟基磷灰石涂层，覆盖在金属杯主体的外壁面上，其中，羟基磷灰石涂层包括叠置设置的多个第一层结构，由远离至靠近金属杯主体的方向上，多个第一层结构的钙磷比逐渐减小。本申请的技术方案能够有效地解决相关技术中的难以兼顾加工工艺和稳定性的问题。

SYSTEMS, DEVICES, AND METHODS FOR DETERMINING FETAL WELLNESS USING FETAL ECG AND FETAL OXIMETRY INFORMATION

Absstract of: WO2026183135A1

Fetal electrocardiogram (ECG) information and fetal oximetry information may be used, in combination, to determine one or more indicators, or predictions, of fetal wellness, blood oxygen saturation, and/or heartrate. At times, the fetal ECG and fetal oximetry information may be input into a fetal health model to determine and/or predict fetal wellness and/or trends in fetal wellness over time. In some embodiments, the fetal ECG and fetal oximetry information may be obtained via a single, combined, device configured to obtain and/or measure the fetal ECG and fetal oximetry information via direct contact with a fetus. Additionally, or alternatively, fetal oximetry information may be measured via a transabdominal fetal oximetry sensor and/or transcervical device configured to be positioned in the vagina and contact the cervix.

GEOGRAPHICALLY DISTRIBUTED DENTAL CARE MANAGEMENT SYSTEM FOR TREATMENT COORDINATION, TRANSPARENT ALIGNER FABRICATION, AND SPECIALIST COLLABORATION

Absstract of: WO2026181074A1

A system and method for managing dental treatment across geographically distributed clinics utilize a digital imaging module to capture intra-oral digital scans. A treatment planning module formulates a dental treatment plan validated by a remote orthodontic specialist. A patient management module orchestrates a competitive tender process to select an executing general dentist from a plurality of candidates based on weighted criteria comprising cost, proximity, and performance ratings. A manufacturing module interfaces with distributed laboratories for aligner fabrication. In some embodiments, the system incorporates a blockchain network with smart contracts for milestone-based financial execution and an artificial intelligence module for predictive treatment optimization. A real-time interactive aligner device comprising electromechanical micro-actuators enables remote geometric adjustments of the aligner in response to specialist instructions. A communication interface facilitates continuous feedback and oversight between patients, specialists, and selected providers, ensuring unified clinical quality and operational efficiency across the distributed network.

IMPROVED EVALUATION OF MEDICAL DEVICE RELATED DATA

Nº publicación: WO2026180968A1 03/09/2026

Applicant:

COCHLEAR LTD [AU]
COCHLEAR LIMITED

Absstract of: WO2026180968A1

A method including executing an automatic evaluation of data residing on a computing system pertaining to a specific medical device. The method comprising obtaining access to a computing system, and via the computing system, obtaining access to data based on medical device settings and/or phenomena recorded in association with the medical device and executing an automated evaluation of the accessed data and gauging efficacy of the medical device based on results of the automated evaluation.