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181
results.
Updated on
23/12/2025 [07:09:00]
Results 50 to 75 of 181
Absstract of: WO2024238462A2
A computer-implemented method for predicting tooth positions includes a) defining a plurality of tooth positions corresponding to a plurality of teeth in a dental arch; b) defining a plurality of appliance positions of an orthodontic appliance; c) determining, for each tooth, one or more tooth position differences; d) determining, for each tooth, one or more appliance position differences; e) determining, for each tooth, one or more appliance-tooth relative differences; f) modifying each of the plurality of tooth positions based on the corresponding one or more appliance-tooth relative differences; g) iteratively repeating steps c) to f) until a maximum change in each of the plurality of tooth positions is less than a convergence threshold; and h) defining the plurality of tooth positions obtained in the final iteration of step g) as a plurality of predicted tooth positions.
Absstract of: US2025375275A1
A method of producing a dental object (100), including the steps of printing (S101) the dental object by means of a production material and a support structure by means of a meltable support material layer by layer; melting (S102) the support material; and absorbing (S103) the molten support material in the production material of the printed dental object.
Absstract of: CN121101779A
本发明涉及牙科医疗器械领域，公开了一种具有区域差异化物理性能的牙科矫治器及其增材制造方法。该矫治器包括由光固化树脂制成的三维壳体结构，所述树脂含有聚氨酯丙烯酸酯和单体。通过调节打印工艺参数，使基体不同区域获得差异化的力学性能，从而在同一矫治器内对不同牙齿施加方向和大小不同的矫治力，以满足临床复杂需求。所述矫治器的材料性能包括：拉伸模量420～2650MPa、屈服强度22～78MPa、屈服应变大于1.8%、断裂应变大于10%、玻璃化转变温度大于40℃，且平均厚度小于2.0mm。本发明方法工艺简便，可提高矫治精度与生物相容性，提升治疗效率。
Absstract of: WO2025255124A1
A method is provided for coating tablets on-demand in a miniaturized coating apparatus. A supply of tablets are provided, each having dimensions and a mass. The supply of tablets together has a total number, a total mass and a total volume. In some aspects, specifications are selected for constructing a customized rotatable drum based on tablet dimensions, tablet number, total mass, total volume, physical and/or chemical properties of coating material(s) to be applied to the tablets, or a combination thereof. In some embodiments, the rotatable drum may be formed by 3D printing.
Absstract of: CN120603611A
The present invention provides articles for improving healing of wounds, preferably burn wounds. In some preferred embodiments, the article is a matrix formed from a mixture of two or more polysaccharides, the matrix comprising an active ingredient, the active ingredient being an extract from differentiable cells.
Absstract of: CN120693245A
This disclosure discusses techniques for securing a thermoformed model, including a locator plate for receiving and securing an individual unique dental model having a polygonal incision, where the locator plate has at least one ball plunger (108) located within a raised polygon (102), the at least one ball plunger has a cylindrical body, a spring, and a ball extending partially outside the cylindrical body. The disclosure also includes a system for thermoforming an orthodontic appliance and a method thereof.
Absstract of: WO2025255553A1
A physiological monitoring device, the device having a housing formed by two rigid structural elements, a soft elastomeric part mechanically locked between the two rigid elements, an electromechanical film sensor assembly positioned beneath the soft part, and a conductive electrode that is arranged above the electromechanical film. The electrode includes electrical connection routed to the printed circuit board (PCB), and the device includes electronics for signal processing, wireless communication, and power management.
Absstract of: WO2025254423A1
The present invention relates to a drug-loaded filament comprising topiramate and a pharmaceutical preparation for preventing or treating obesity prepared using same. Topiramate contained in the filament exhibits an amorphous nature, and thus can be used in the preparation of a pharmaceutical preparation that is easily dissolved, thereby facilitating application and absorption in the body. The drug-loaded filament comprising same can be applied to 3D printing such as fused deposition modeling (FDM) and effectively used in the preparation of a pharmaceutical preparation that can be administered via various mucosal administration routes, such as oral mucosa, e.g., sublingual and buccal mucosa, and nasal mucosa in the nasal cavity or the like.
Absstract of: US2025375383A1
At present, the most prevalent pharmaceutical dosage forms, the oral immediate-release tablets and capsules, are porous solids of compacted drug and excipient powders. Upon ingestion, physiological fluid percolates the open pores, and the dosage form disintegrates and the drug dissolves. Because the pores in the compacted solids are not well connected, however, fluid percolation generally is not uniform, and the drug release rate is difficult to predict and control. To overcome such limitations, therefore, herein a structured solid dosage form is disclosed. The structured solid dosage form comprises a structural assembly of one or more repeatably arranged, extruded structural elements. The elements comprise segments separated and spaced from adjoining segments by free spacings defining one or more substantially interconnected free spaces, or channels, in the dosage form through which a physiological fluid may percolate. The disclosed dosage form enables more predictable drug release rates, and can be readily manufactured by 3D-printing.
Absstract of: US2025375266A1
The present technology comprises methods of manufacturing an orthodontic appliance. For example, a method can include forming an orthodontic appliance in an intermediate configuration by a casting process. The method can further include securing the appliance to a shape forming fixture such that the appliance assumes a desired configuration. The shape forming fixture can comprise a gingiva portion including a surface having a shape corresponding at least in part to a gingiva of a patient and a securing portion carried by the gingiva portion and configured to releasably secure to a portion of the appliance. The method can further include setting a shape of the appliance while the appliance is secured to the shape forming fixture.
Absstract of: US2025375324A1
A diaper insert insertion aid apparatus is disclosed, designed to streamline and simplify the process of inserting absorbent inserts into cloth diaper covers. The apparatus comprises a main body configured to hold multiple reusable cloth diaper inserts, a fastening mechanism to secure the inserts in place, and resilient pads for stability. In one embodiment, the main body further includes a handle for ease of manipulation. The apparatus can accommodate inserts with or without pockets, and the pocketed inserts can be further supported by a dedicated structure within the apparatus. This invention aims to address the inconvenience and physical strain associated with traditional manual insertion methods, making cloth diapering more accessible and appealing to a wider range of users, including those with limited dexterity or handling multiple diapers. The apparatus is adaptable to various insert configurations and can also find possible applications in other textile manufacturing processes.
Absstract of: US2025375304A1
An expandable spinal implant includes a plug movably disposed in a distal aperture and an interior portion of a frame. The plug may be configured for movement from a first position to a second position. The plug may include a plug proximal end, an opposite plug distal end, a body portion, and a head portion extending from the body portion to the plug distal end. Movement of the plug from the first position to the second position, and corresponding interaction of a head portion with a first endplate portion may causes the first endplate portion and a first distal end portion to move away from the frame and interaction of the head portion with a second endplate portion may cause the second endplate portion and a second distal end portion to move away from the frame to move the implant from a collapsed position to an expanded position.
Absstract of: US2025375921A1
A method of producing a dental object, including the steps of printing (S101) a printing layer of the dental object; evaporating (S102) a solvent of the printed printing layer; and detecting (S103) a temperature profile during evaporation of the solvent.
Absstract of: US2025375287A1
Certain aspects of the present disclosure provide a flexible scaffold implant comprising a plurality of layered structures, the plurality of layered structures comprising: a first layered structure having a three-dimensional (3D) shape and formed from a bioresorbable material, and a second layered structure conforming to the corresponding 3D shape of the first layered structure and formed from the bioresorbable material. The first layered structure is arranged in proximity to the second layered structure. The first layered structure is configured to dissolve for resorption at a different rate than the second layered structure based on design elements of the first layered structure and the second layered structure. The plurality of layered structures are flexible.
Absstract of: US2025375273A1
A method of producing a dental object, including the steps of printing (S101) a substructure; printing (S102) an intermediate layer from a support material on the substructure; and printing (S103) the dental object from the production material for the dental object on the intermediate layer.
Absstract of: US2025375275A1
A method of producing a dental object (100), including the steps of printing (S101) the dental object by means of a production material and a support structure by means of a meltable support material layer by layer; melting (S102) the support material; and absorbing (S103) the molten support material in the production material of the printed dental object.
Absstract of: US2025375299A1
A method for fabricating a resorbable scaffold for regeneration of meniscal tissue is disclosed. The method includes fabricating a polymer filament network using 3D printing in accordance with a digital model of the polymer filament network, such that the polymer filament network will include a first plurality of layers comprising the circumferentially-oriented filaments alternating with a second plurality of layers comprising the radially-oriented filaments, the polymer filament network having a three-dimensional shape and geometry between a first layer and a second layer which is substantially the same as a three-dimensional shape and geometry of the resorbable scaffold.
Absstract of: US2025375269A1
The present disclosure discusses techniques for fabricating bite interference elements within polymeric dental appliances. The techniques disclose at least one polymeric shell that includes a number of cavities shaped to fit over a patient's teeth. The polymeric shell includes an occlusal appliance surface shaped to fit over an occlusal tooth surface of the patient. One or more bite interference elements are formed within the occlusal appliance surface, and each bite interference element includes a partially disc-shaped feature extending radially away from the occlusal tooth surface when worn by the patient.
Absstract of: US2025376651A1
A culture apparatus includes a bioprinter that linearly prints bioink, a housing configured to accommodate a substrate that supports the bioink, a driver that moves the bioprinter and the housing relatively to each other, and a controller. The controller is configured to control the driver to locate an outlet of the bioprinter at a printing start position in the housing and thereafter to move the outlet in a first direction in the substrate within the housing. The controller is configured to control a pump for the bioink to start application of a pressure to the bioink after the outlet is inserted in the substrate and before the outlet starts moving from the printing start position in the first direction.
Absstract of: DE112024000859T5
Enthalten ist ein computerimplementiertes Verfahren zum Schließen eines oder mehrerer Löcher in einem unteren Abschnitt eines dreidimensionalen digitalen Präparationsmodells einer Zahnpräparation. Der Zahn ist für die Aufnahme eines Zahnrestaurationselements präpariert, wobei eine untere Grenze des unteren Abschnitts der Präparation in Form einer stufenlosen Kante präpariert ist. Das Verfahren umfasst den Empfang des dreidimensionalen digitalen Präparationsmodells des präparierten Zahns. Ein oder mehrere zu schließende Löcher des dreidimensionalen digitalen Präparationsmodells werden innerhalb des unteren Abschnitts erfasst. Es wird ein Präparationswinkel für die Präparation des unteren Abschnitts bestimmt und das oder die erfassten Löcher werden geschlossen. Das Schließen umfasst eine Extrapolation des unteren Abschnitts in die Löcher unter Verwendung des ermittelten Präparationswinkels.
Absstract of: EP4659703A2
The present disclosure relates to single tooth or full arch dental restoration. In cases where patients have insufficient bone stock for conventional root-form dental implants, current solutions often fail to restore function. The present disclosure describes a transalveolar dental implant for single tooth or full arch dental restoration. The transalveolar dental implant is comprised of a post and a bone plate, the bone plate having a contoured portion fabricated to match the topography of a bony surface of the facial skeleton. Through primary fixation of the contoured portion of the bone plate, the transalveolar dental implant improves function and outcomes in affected patients.
Absstract of: US2024252719A1
A method for in-vivo cell replacement is disclosed. The method includes steps of extracting donor cells from a donor tissue of a patient; generating donor material including the donor cells; removing one or more cell layers from a receiver tissue of the patient to expose a target layer of the receiver tissue while maintaining operation of a vasculature of the receiver tissue; and printing the donor material onto the target layer of the receiver tissue. A tissue position assembly, a composition for use in a treatment of bladder damage or bladder dysmorphism, and a system for supplying donor material to a bioprinter are also disclosed.
Absstract of: EP4659719A1
Dispositif médical (100,200,300,400) pour immobiliser un membre ou une articulation, ledit dispositif comportant au moins deux demis-coques complémentaires (10a-b,20a-b,30a-b,40a-b) de forme sensiblement alvéolaire, lesdites demis-coques comprenant chacune au moins deux surfaces de contact (101a-b,102a-b,201a-b,202a-b,203a-b,301a-b,302a-b,303a-b,401a-b,402a-b), un système de fermeture (12,22,32,42), le système de fermeture (12,22,32,42) étant positionné dans des logements (103a-b,204a-b,304a-b,403a-b) des surfaces de contact (101a-b,102a-b,201a-b,202a-b,203a-b,301a-b,302a-b,303a-b,401a-b,402a-b), ledit système de fermeture étant magnétique, ledit système de fermeture étant invisible lorsque le dispositif médical (100,200,300,400) est assemblé.
Absstract of: CN120641167A
A drug delivery device comprises at least one tissue penetrating member configured to be embedded in tissue, the at least one tissue penetrating member comprising: a plurality of lumens, and at least one payload comprising at least one active pharmaceutical ingredient (API) loaded into the plurality of lumens, the at least one tissue penetrating member is configured such that when the at least one tissue penetrating member is embedded in the tissue, the at least one API can be absorbed into the tissue wherein a ratio of a surface area of the plurality of lumens to a volume of the plurality of lumens is at least 0.5: 1.
Nº publicación: EP4658482A1 10/12/2025
Applicant:
OHIO STATE INNOVATION FOUNDATION [US]
Ohio State Innovation Foundation
Absstract of: WO2024163434A1
A collimator assembly for a linear accelerator for use in FLASH radiotherapy includes a collimator and a tray. The collimator includes an elongated body and a base and can also include an opening that defines a central bore formed in the elongated body and the base and extending the length of the collimator along a central axis. The tray includes a central opening having a larger cross-section than the elongated body of the collimator but smaller than the base of the collimator to allow only the elongated body of the collimator to pass therethrough such that the collimator is retained by the tray for reversible installation on the linear accelerator. The tray is adapted to be removably installed on accessory rails of the linear accelerator. Both the collimator and tray may be fabricated by 3D printing to allow for customization.
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