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151
results.
Updated on
16/02/2026 [07:04:00]
Results 50 to 75 of 151
Absstract of: CN120712122A
A drug delivery device includes a substrate; and a plurality of tissue penetrating members 3D printed onto the substrate and configured to be embedded into tissue, wherein at least one tissue penetrating member of the plurality of tissue penetrating members is configured to anchor the drug delivery device to the tissue; and at least one payload comprising at least one API loaded into at least one of the substrate and the plurality of tissue penetrating members for absorption into the tissue when the at least one tissue penetrating member is embedded in the tissue.
Absstract of: CN120603620A
A drug delivery device comprises at least one tissue penetrating member configured to be embedded in tissue, the at least one tissue penetrating member comprising: at least one lumen formed below an outer surface of the at least one tissue penetrating member, the at least one cavity has a depth from the outer surface and a width in a direction orthogonal to a direction of the depth from the outer surface; and at least one opening in the outer surface, the at least one opening in communication with the at least one lumen such that at least one API loaded into the at least one lumen can be absorbed from the at least one lumen into the tissue, where the width of the at least one opening is less than the width of the at least one lumen.
Absstract of: US20260035592A1
Provided is a cationically polymerizable resin composition for three-dimensional photofabrication that contains a cationically polymerizable monomer (A), a photocationic polymerization initiator (B) containing a photoacid generator (b1), a photosensitizer (b2), and an electron-donating compound (b3) that is at least one type of thiophene compound selected from the group consisting of monothiophene compounds having a π-conjugated substituent as a substituent, dithiophene compounds, and trithiophene compounds, and a basic compound (C). The content of the electron-donating compound (b3) is 0.001-10 parts by mass and the content of the basic compound (C) is 0.0001-5.0 parts by mass per 100 parts by mass of the cationically polymerizable monomer (A). Also provided is a method for producing a three-dimensional photofabricated product using this cationically polymerizable resin composition for three-dimensional photofabrication.
Absstract of: US20260033923A1
A system and method for generating a 3D-printed medical appliance treatment plan and providing a set of 3D-printed medical appliances in accordance therewith, the method comprising: generating a dynamic 3D-printed medical appliance treatment plan generation model; obtaining a patient record; receiving 3D scanning data of the patient; generating a 3D-printed medical appliance treatment plan by applying the patient record and the 3D scanning data to the dynamic 3D-printed medical appliance treatment plan generation model; providing the 3D-printed medical appliance treatment plan to a medical practitioner; providing a manufacturing request to a manufacturer system for manufacturing a set of 3D-printed medical appliances; providing the set of 3D-printed medical appliances to the patient; receiving feedback from the medical practitioner regarding the 3D-printed medical appliance treatment plan; modifying the dynamic 3D-printed medical appliance treatment plan generation model based on the feedback.
Absstract of: US20260033920A1
Wire attachment dental appliances. A shell may be shaped to receive teeth of a dentition. The shell may include an attachment material reservoir that is configured to accept an attachment material therein. A wire attachment member may be configured to be secured to the shell. The attachment material reservoir and the wire attachment member may be aligned along an arch line of the shell in a manner that allows a wire to simultaneously pass through the attachment material reservoir and engage with the wire attachment member.
Absstract of: US20260033918A1
The present disclosure provides a support of a 3D printed orthodontic dental appliance is provided. The orthodontic dental appliance includes a shell structure defined by an inner contour surface and an outer contour surface. The support comprises: a middle support including a middle support base mesh and a plurality of middle support struts and a main support configured to connect the middle support to a build platform of a 3D printing device used to print the orthodontic dental appliance. One end of each middle support strut of the plurality of middle support struts is connected to the orthodontic dental appliance at a junction of the inner contour surface and the outer contour surface, and the other end of the middle support strut is connected to a rim of the middle support base mesh.
Absstract of: US20260033957A1
In one embodiment, an intervertebral implant includes a body and a locking element. The body includes a leading surface and a trailing surface opposite the leading surface. The body also includes first and second bone fastener passageways through the implant body and a cavity in between the first and second passageways. The cavity includes a trailing wall that separates the cavity from the trailing surface. The locking element is disposed in the cavity such that part of the locking element is visible through an access opening in the trailing wall so that the locking element may be rotated from outside of the implant. In a first rotational position, a first part of the locking element is located within one of the first and second passageways and in a second rotational position, the first part of the locking element is inside the body covered by the trailing wall.
Absstract of: US20260034341A1
Pliers for engaging an aseptic connection assembly is disclosed. The pliers has two arms. Each arm includes a hinge portion, a handle portion, and a pair of phalanges. The hinge portion has a hole for forming a hinge. The handle portion couples to the hinge portion. The pair of phalanges is on a plane perpendicular to the plane of rotation of the two arms and is coupled to the hinge portion. The phalanges couple to sides of outer surfaces of a pair of connector bodies. The hinge is formed by a rod inserted through the holes of the hinge portions of the two arms. An actuation force applied to the handle portions causes the two arms to rotate about the hinge, causing the pair of phalanges to move together to snap together the pair of connector bodies, thereby engaging the aseptic connection assembly.
Absstract of: AU2025205647A1
An implant having two adjacent solid parts, a third solid part disposed between the two solid parts, and a porous part extending from the solid parts. The implant is fabricated by a process that includes first assembling the solid parts before additively manufacturing the porous part on surfaces defined by the solid parts. This process may include positioning a first fabricated component adjacent to a second fabricated component such that a side surface of the first fabricated component and a side surface of the second fabricated component form a build surface. Then additively manufacturing a structure on the build surface such that the structure extends across and is permanently fixed to both of the side surfaces of the first and the second fabricated components such that the first and the second fabricated components form part of the implant. An implant having two adjacent solid parts, a third solid part disposed between the two solid parts, and a porous part extending from the solid parts. The implant is fabricated by a process that includes first assembling the solid parts before additively manufacturing the porous part on surfaces defined by the solid parts. This process may include positioning a first fabricated component adjacent to a second fabricated component such that a side surface of the first fabricated component and a side surface of the second fabricated component form a build surface. Then additively manufacturing a structure on the build surface such that th
Absstract of: WO2026030357A1
Disclosed herein is a microfluidic device for priming, collection and recovery of immune cells comprising: a) two separate fluidic channels: i) a first channel, wherein the first channel is infused with immune cells, and ii) a second channel, wherein the second channel acts as a collection reservoir for transmigrated cells, and; b) a microporous membrane interface, present between the first channel and the second channel, wherein the microporous membrane is functionalized on the first channel surface with adhesion molecules. Also disclosed are methods of creating enhanced cells, and using them in treatment of individuals in need thereof.
Absstract of: WO2024120583A1
The invention relates to a tool for use as a micromanipulator and to a method for producing the tool. The tool consists of a plurality of parts in the form of - a frame (1) which is oriented along a longitudinal axis (L) and which is arranged as a hollow body around an interior, - at least one manipulator element (2) arranged on a first end face (1.1) of the frame (1), and - at least one actuation element (3) which is arranged on a second end face (1.2) opposite the first end face (1.1) and which is mounted slidably and axially movably in the interior of the frame (1), said parts being connected interlockingly and movably to one another by means of necessary connecting and bearing elements, and the tool being entirely generated by additive manufacture, including all the necessary gaps between the parts movably connected to one another. According to the method, the tool with all its parts and with the gaps between the movable parts is manufactured entirely by additive manufacture in one processing operation.
Absstract of: CN121445944A
本发明涉及骨修复技术领域，尤其涉及一种骨缺损修复的羟基磷灰石/二氧化锆复合多孔支架的3D打印制备方法、支架和应用。本发明以CT/Micro‑CT重建获得个性化STL，采用高固含光敏陶瓷浆料（HA:ZrO2=25:75～45:55）进行DLP成形；经分段脱脂与分段烧结，在钙磷酸盐/ZrO2界面原位构建连续CaZrO3/或Ca2Zr7O16中间层（覆盖率60%～95%、厚度80～250nm），并保持t‑ZrO₂≥70%。所得TPMS/晶格支架孔隙率45%～70%、连通率≥97%，在多孔条件下仍具抗压≥45MPa、106次疲劳极限≥6MPa；通过受控冷却与SBF预活化可实现HA快速再生（t50≤24h、7d≥2μm）。该方法兼顾个性化成形、界面键合与早期成骨性能。
Absstract of: US2025049723A1
Provided herein are devices and systems for depositing a material or manufacturing a product, such as a pharmaceutical dosage form, by additive manufacturing. Further provided are methods of using the devices and systems, as well as methods of manufacturing a product, such as a pharmaceutical dosage form, by additive manufacturing. In certain embodiments, the device includes a material supply system configured to melt a pressurized a material, a pressure sensor configured to detect a pressure of the material within the device, and a control switch comprising a sealing needle operable in an open position and closed position. The sealing needle extends through a feed channel containing the material and includes a taper end, wherein the tapered end of the sealing needle engages a tapered inner surface of a nozzle to inhibit flow of the material through the nozzle when the sealing needle is in the closed position.
Absstract of: JP7810304B1
【課題】本開示は、優れた印刷安定性を保ちつつ、組み合わせる色素の種類によらず耐光性に優れ、かつ広い色域を再現できる錠剤用インクジェットインクセット、錠剤用インクジェットインクのシリーズ、錠剤用混合インクジェットインクおよび錠剤印刷物を提供することを目的とする。【解決手段】本実施形態に係る錠剤用インクジェットインクセットは、可食性の染料と、溶媒として水およびエタノールとを含み、前記染料の種類が互いに異なる複数の錠剤用インクジェットインクを備え、前記複数の錠剤用インクジェットインクのうち少なくとも１つには褪色抑制剤として還元イソマルツロースが含まれており、前記褪色抑制剤を含む前記錠剤用インクジェットインクにおける前記褪色抑制剤の含有量Ｆ［ｗｔ％］と、前記染料の含有量Ｄ［ｗｔ％］との比（Ｆ／Ｄ）が０．２以上３０．０以下の範囲内である。【選択図】図６
Absstract of: CN223860972U
本实用新型公开了一种用于3D打印骨填充物的调整装置，涉及医疗器械技术领域。该一种用于3D打印骨填充物的调整装置，包括底座，所述底座一侧滑动设置有活动套。该一种用于3D打印骨填充物的调整装置，通过调节活动套和调节头的位置，使夹持机构位于需要连接位置处的正上方，在将桥接棒块固定后，向下压动齿杆，齿杆在压力左右下移动并使桥接棒块接近连接处，在进一步调节活动套与调节头的位置后，继续下压齿杆，由于限位齿轮被卡销阻挡，使得桥接棒块被精确紧密地压在连接处，使得桥接棒块在固定时更加稳定，且方便调节桥接棒块的位置，结构简单，操作方便，提高了手术效率。
Absstract of: CN223861105U
本实用新型的目的在于提供一种密孔型锌合金口腔膜，其结构包括：锌合金膜，织物膜，织物膜覆盖在锌合金膜，锌合金膜利用粉末冶金技术成型，可以整体完全降解，还能够有效保持金属对于屏蔽空间的有效支撑，而织物膜具有微纳级孔隙率，与锌合金的密孔部分组成多级孔隙结构，增加了与营养物质的交换面积，克服了营养物质无法穿过金属膜的问题。
Absstract of: AU2024276549A1
Methods of manufacturing a porous device for diffusing a fragrance using additive manufacturing including iteratively spreading a loose powder and selecting at least one process parameter to create a porosity within the porous device adapted to carry the fragrance from a fragrance reservoir to an exterior surface of the porous device. An additively manufactured device for diffusing a fragrance includes a diffuser having a plurality of pores defining a porosity of the diffuser, the porosity defining at least one of a rate of absorption, an amount of storage, and a rate of diffusion of the fragrance. A method of using a porous device includes filling the plurality of pores with fragrance and diffusing the fragrance from an exterior surface.
Absstract of: CN121445530A
本发明一种增材制造的空心髋臼杯假体及其制作方法涉及人工髋关节假体技术领域，包括依次连接的堵销、杯体以及多孔结构；杯体的内型面包括内端面、内球面、锥面、防旋凸耳安装槽和卡合槽，杯体的内型面用于安装臼衬；杯体的锥面被用于安装陶瓷衬，而内端面、内球面、防旋凸耳安装槽和卡合槽不与陶瓷衬接触；多孔结构附着在杯体的外型面上，其外型面呈半球形或半椭球形，止于长轴；多孔结构与杯体回转轴为短半轴；杯体的顶端设有一个用于术中安装的螺纹孔，杯体的端面上设有至少一个排粉孔并在排粉后安装堵销；杯体的内球面处不设置或设有至少一个用于安装植入初期固定的钛钉的钛钉孔；端面与外型面之间设有连通的空腔。
Absstract of: CN121447064A
本发明涉及金属增材制造技术领域，具体涉及一种通过多参数协同控制的钴铬合金成型方法及牙科修复体，成型方法包括如下步骤：1)粉末预处理：对钴铬合金粉末进行真空等离子活化得到活化处理的钴铬合金粉末；在活化处理的钴铬合金粉末表面附着纳米氧化物表面修饰剂得到预打印粉末；2)3D打印：在对步骤1)获得的预打印粉末打印过程中，采用梯度能量打印和动态气氛控制，获得钴铬合金成型件。本发明实现金属表面氧化层的精确可控生长，使氧化层厚度稳定在理想范围，以满足金瓷高强度结合的需求。
Absstract of: TW202510819A
The disclosure provides a 3D tissue reconstruction implant having a hydrophilic implant surface and consisting of a bio-resorbable material, wherein the implant surface is considered hydrophilic when assessed using an ink test following ISO 8296:2003 and adapted to a 3D surface, wherein said ink test comprises incubating the implant for 1 min in a solution consisting of an ink with a surface tension of 72 mN/m and water and wherein after incubation of the implant in said solution an ink colored implant surface is indicative for a hydrophilic implant surface. The disclosure also provides said implant for use in tissue reconstruction, (soft) tissue support, tissue augmentation and/or implant revision and the use of said implant for reconstructing, augmenting and/or revising a tissue and/or supporting a (soft) tissue, respectively, wherein the implant is inserted into a patient. Further the disclosure provides a method of manufacturing a tissue reconstruction implant with a hydrophilic implant surface.
Absstract of: WO2024233888A1
A dose divider for releasable attachment to a plunger rod of a syringe comprises first and second arms. A front portion of the first arm and the front portion of the second arm form a channel therebetween for receiving the plunger rod. A resilient hinge pivotably couples the first arm and the second arm such that the dose divider is reversibly movable between first and second configurations. When the dose divider is in the second configuration, the dose divider is configured to receive the plunger rod in the channel through an opening formed between the front portions of the first and second arms. The channel has a shape configured to receive a specific outer shape of the plunger rod. The front portions of the first and second arms are closer when the dose divider is in the first configuration than when the dose divider is in the second configuration.
Absstract of: WO2025018078A1
A drug packaging device is provided with a feeding mechanism for feeding a long sheet, a sealing device for sealing the long sheet to form a packaging bag in which a drug is accommodated, and an identifier imparting means. The long sheet is provided with a first surface constituting the inner surface of the packaging bag. The identifier imparting means is configured to apply ink onto the first surface of the long sheet to form an identifier for identifying information regarding the drug to be packaged.
Absstract of: CN121422295A
本发明属于生物医用材料与口腔种植技术领域，具体涉及一种具有梯度多孔结构和分区改性表面的钛合金口腔种植体及其制备方法。种植体总体分为上下两区域，下区域采用创新三级梯度多孔结构，颈缘区为小孔，中部过渡区为中孔，根区为大孔；实现种植体嵌入颌骨部位后弹性模量从冠部到根部的逐步降低，与天然牙槽骨力学性能相匹配，有效降低应力屏蔽效应。种植体表面通过飞秒激光技术进行分区改性处理，上区域处理后显著促进小鼠成纤维细胞的粘附和增殖；下区域处理后形成特定的微纳米复合结构，可显著提高成骨细胞的增殖率和碱性磷酸酶活性。本发明通过结构‑功能一体化设计，同时实现力学适配性优化、软组织封闭性增强和骨结合效能提升。
Absstract of: KR20260014071A
본 발명은 3차원 바이오프린팅 구조물의 제조방법 및 상기 방법으로 제조된 3차원 바이오프린팅 구조물에 관한 것으로, 본 발명에 따르면, 기존에는 프린팅이 어렵던 높은 세포적합성의 저점도 생체수화젤로 고해상도 3차원 구조를 제작하여 높은 생체모사도의 체외 세포배양모델을 제작할 수 있어, 미세혈관 네트워크 조립, 유방암 미세환경 구현, 신경 네트워크 형성과 같은 복잡한 체내 미세환경을 재현하는 in vitro 모델에 활용할 수 있다.
Nº publicación: CN121427135A 30/01/2026
Applicant:
郑州市中心医院
Absstract of: CN121427135A
本申请提供了一种3D打印相变导热温度监控贴片的制备方法，涉及温度监控贴片技术领域，包括以下组分：石墨烯、羧基化碳纳米管、海藻酸钠、月桂酸和硬脂酸。本发明通过利用石墨烯、羧基化碳纳米管、海藻酸钠、月桂酸和硬脂酸制备多重氢键作用，互锁相变材料，调控配方中的组分和3D打印工艺参数，制备了一种适配3D打印的流变性需求的配方，并且能够让碳材料有合适的取向流，在较低的含量下实现导热和导电，具有高精度的成型控制，有较好的人体舒适性和较高的温度响应性。
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