Alerta

CURABLE COMPOSITION FOR THREE-DIMENSIONAL STEREOLITHOGRAPHY, METHOD FOR PRODUCING SAME, METHOD FOR PRODUCING THREE-DIMENSIONAL STEREOLITHOGRAPHIC PRODUCT, AND METHOD FOR PRODUCING DENTAL RESTORATION ARTICLE

Resumen de: AU2024424532A1

Provided are: a curable composition for three-dimensional stereolithography, which contains 100 parts by mass of a polymerizable monomer component (A), 40-400 parts by mass of an inorganic filler (B), 0.01-5 parts by mass of a photoinitiator (C), and 0.01-2.5 parts by mass of an activation light absorber (D), and in which 10-90 mass% of the inorganic filler (B) is contained as an organic-inorganic composite filler (E), the value of light scattering index Sc serving as an index of the proportion of light scattered laterally when being irradiated with activation light is 10% or less, and the rate of transmission for activation light in a state prior to being optically cured is 1-50%; and a method for producing the curable composition for three-dimensional stereolithography. The present invention also provides a method for producing a three-dimensional stereolithographic product and a method for producing a dental restoration article, in both of which said curable composition for three-dimensional stereolithography is used.

MEDICAL DEVICE HUB POSITION DETECTION SYSTEM, METHOD, AND APPARATUS

Resumen de: AU2024415223A1

A system, method, and apparatus are disclosed for determining positions of medical devices within a hub, which comprises a number of apparatuses that are linked together in a stacked configuration. A medical device hub includes a connectivity apparatus that is communicatively coupled to a medical network and/or a monitoring device. Additionally, the medical device hub includes one or more docking apparatuses. Each docking apparatus can accommodate two or more infusion pumps. The number of docking apparatuses used in the medical device hub depends on the number of infusion pumps needed for a patient treatment. The medical device hub enables multiple docking apparatuses to be stacked as needed while enabling the infusion pumps to be operated independently and removed from the medical device hub as needed, even during a treatment without interruption. Such a configuration provides a scalable, flexible, and adaptable system that aggregates infusion pumps into a relatively small footprint.

Classification of 3D Oral Care Representations

Resumen de: US20260211979A1

0000 Systems and techniques for classifying a 3D representation of oral care data are disclosed. The method involves receiving a first 3D representation comprising one or more mesh elements and providing it as input to a trained autoencoder network. The processing circuitry computes one or more mesh element features for the mesh elements and provides them to the trained autoencoder network. By executing the trained autoencoder network, the first 3D representation of oral care data is encoded into one or more latent space representations. These latent space representations are specifically designed for utilization by a machine learning model for the classification of the first 3D representation of oral care data. These systems and techniques enable accurate and efficient classification of 3D representations, enhancing the analysis and understanding of oral care data for improved diagnosis and treatment planning.

Setups Comparison for Final Setups and Intermediate Staging in Clear Tray Aligners

Resumen de: US20260207298A1

Systems and techniques for comparing orthodontic setups are disclosed. The method involves receiving an instant orthodontic setup and a reference orthodontic setup, both comprising three-dimensional (3D) representations of one or more teeth. The processing circuitry compares at least one aspect of the instant orthodontic setup with the corresponding aspect of the reference orthodontic setup to compute a comparison metric. The comparison metric represents the degree of similarity or dissimilarity between the two setups. The processing circuitry then outputs the computed comparison metric. These systems and techniques enable efficient and accurate comparison of orthodontic setups, aiding in the evaluation and assessment of treatment plans and facilitating informed decision-making in orthodontic procedures.

TRACKING SYSTEM AND METHOD FOR PATIENT TRANSFER DURING IMAGING AND TREATMENT PROCEDURES

Resumen de: US20260213007A1

0000 A system supports a patient and tracks the position and/or orientation of a patient support. The system has a patient transfer apparatus; at least one reference surface; a sensor acquiring input related to a position of the patient transfer apparatus; at least one processor to process and convert the input from the at least one sensor; at least one transmitter to transmit the input from the at least one sensor to the at least one processor; and a tracking feature disposed on the reference surface. The sensor is coupled to the patient transfer apparatus to detect the tracking feature disposed in or on the at least one reference surface and the at least one transmitter transmits the input from the sensor to the at least one processor for processing and conversion into coordinates within a reference frame in at least one degree of freedom.

Methods of drug dosing based on early pharmacokinetics

Resumen de: US20260212981A1

0000 Provided is a computer-implemented method for predicting a pharmacokinetic feature for a drug administered to a subject, such as maximum concentration or time to maximum concentration. The method includes: contacting a fluid of the subject with an electrochemical aptamer-based sensor capable of detecting the drug, receiving a series of output values of the electrochemical aptamer-based sensor over a period of time, and using the series of output values to predict the pharmacokinetic feature.

Systems And Devices For Collecting Health Data And Methods Of Using Same

Resumen de: US20260213009A1

Technologies are disclosed for assessing a subject's health based on health-related information. Devices and/or techniques may include a memory, a display device, a processor, and/or a transceiver. The transceiver may be in communication with one or more sensors. The one or more sensors may be configured to capture one or more characteristics corresponding to the subject. The processor may be configured to receive one or more characteristics corresponding to the subject via the transceiver. The processor may be configured to determine at least a first indication of the subject's health based, at least in part, on the one or more characteristics corresponding to the subject. The processor may be configured to provide a visual representation of the first indication of the subject's health via the display device.

AUTOMATED ANALYSIS OF ECHOCARDIOGRAPHIC IMAGES

Resumen de: US20260212505A1

Apparatus and methods are described, including receiving a stream of echocardiographic images of a patient's heart that are acquired from a plurality of different views, analyzing the stream of echocardiographic images, and determining a cardiac-state age of the patient based upon the analysis, the cardiac-state age of the patient being indicative of an age that the patient's heart appears to be, based upon the analysis of the stream of echocardiographic images. Other applications are also described.

DIAGNOSIS AND TREATMENT OF LONG-COVID

Resumen de: US20260210975A1

0000 A method of determining a risk of developing a neurological disorder in a Long-COVID patient comprising: (a) testing levels of at least one marker associated with a neurologic disorder in a sample taken from the Long-COVID patient, and (b) making a determination that the Long-COVID patient is at risk of developing said neurological disorder when the levels of said at least one marker is increased in the Long-COVID patient compared to healthy control reference levels of said marker. Also a method of determining a risk of developing a cardiometabolic injury in a Long-COVID patient when the levels of expression of a marker associated to a cardiometabolic injury is different in the Long-COVID patient than the levels of said marker in a healthy control. Also methods of treating Long-COVID with a drug effective to mediate the HIF signaling pathway.

Geometric Deep Learning For Final Setups And Intermediate Staging In Clear Tray Aligners

Resumen de: US20260207301A1

Systems and techniques are disclosed for generating setups for orthodontic alignment treatment. The method involves receiving a digital representation of a patient's teeth and at least one value pertaining to the customization of orthodontic treatment. A prediction for one or more tooth movements for a setup is formed by executing a generator network comprising one or more neural networks. The generator network is further trained based on the formed prediction by performing operations that include predicting the tooth movements, quantifying the difference between the predicted tooth movements and reference tooth movements, generating a loss value based on the quantified difference, and modifying the generator network based on the loss value to form a modified generator network. These systems and techniques enable the efficient generation of setups for orthodontic alignment treatment, improving the accuracy and customization of the treatment process.

METHOD FOR DETECTION AND/OR PREDICTING EPILEPTIC SEIZURE ON BASIS OF CONTINUOUS BIOSIGNAL MEASUREMENT, SYSTEM THEREFOR AND COMPUTER SYSTEM-READABLE RECORDING MEDIUM

Resumen de: US20260207120A1

0000 A method for detecting and/or predicting an epileptic seizure based on continuous bio signal measurement by a computer includes: a continuous composite bio signal monitoring step of receiving a composite bio signal including user's electroencephalography (EEG) and head electrocardiogram (ECG) from a sensor unit, preprocessing the received bio signal including the EEG and the head ECG, and converting the preprocessed bio signal into a digital signal; extracting a bio signal feature including a EEG feature and a head ECG feature from a user's bio signal; inputting the bio signal feature including the extracted EEG feature and head ECG feature to a machine learning algorithm to analyze the bio signal feature; and storing or outputting a detection and/or prediction result of the seizure according to the analysis result.

METHOD AND DEVICE FOR PRODUCING AN ARTICLE

Resumen de: US20260208437A1

0000 The invention relates to a method for producing a three-dimensional articles by way of an additive manufacturing method, wherein at least one manufacturing material is introduced in a flowable state into a support material from at least one introduction opening of an introduction needle and is then hardened, and a stiffening material is introduced into the support material and then hardened.

DEVICE FOR MANUFACTURING BIOINK

Resumen de: US20260208138A1

0000 A bio-ink manufacturing device according to the present disclosure is provided. The bio-ink manufacturing device include: a reaction vessel for performing a reaction on tissues of decellularized extracellular matrix and an ink solution; a bio-ink liquefy portion for stirring and compacting the tissues of decellularized extracellular matrix and liquefying the same into bio-ink; and a bio-ink discharge portion discharging the bio-ink whose liquefaction is completed to an outside of the reaction vessel.

BIOINKS AND METHODS OF SYNTHESIZING, CHARACTERIZING, AND DEPLOYING BIOINKS

Resumen de: US20260207790A1

0000 Bioinks and methods of synthesizing, characterizing, and deploying bioinks are described. Compounds and methods of making the same are described. Method of synthesizing pH-responsive polymers are described. Different types of bioinks are described. For example, the described bioinks may comprise: one or more of the pH-responsive polymers; a photoinitiator; and a solvent. Methods preparing bioinks are described. Methods of determining characteristics of bioinks are described. Related apparatus, kits, methods, and systems also are described.

MULTI-TISSUE SEGMENTATION AND DEFORMATION FOR BREAST CANCER SURGERY

Resumen de: US20260207121A1

Example embodiments may include procedures for modeling segmentation and deformation of breast tissue, useable for surgical planning and possibly other procedures. These embodiments involve applying a tumor localization, tumor segmentation, and multi-tissue segmentation procedure to 3D image data of breast tissue, then combining the results of these procedures as well as anatomical feasibilities, in determining most likely tissue types for regions of the 3D image data. Additionally or alternatively, a finite element model can be used to represent the different tissue types in the 3D image data as elements with distinct physical characteristics. Such a model can be used to simulate gravity in a posterior direction to translate the elements from the prone position to a gravity-unloaded position and then from the gravity-unloaded position to a supine position. The translated elements can be interpolated into further 3D image data with identified locations of the tissue types.

MATRICES FOR WOUND HEALING

Resumen de: US20260207811A1

The present invention provides articles for the improved healing of wounds, preferably burn wounds. In some preferred embodiments, the article is a matrix formed from a mixture of two or more polysaccharides, the matrix comprising an active ingredient which is an extract from differentiable cells.

METHOD, APPARATUS, AND SYSTEM FOR CREATING ENVIRONMENT THROUGH AI-BASED NON-CONTACT SLEEP ANALYSIS

Resumen de: US20260207878A1

The present invention relates to a method for controlling an environment adjustment device, comprising: an acquisition step of acquiring environment sensing information; a pre-processing step of performing pre-processing on the acquired environment sensing information; a generation step of generating sleep state information based on the pre-processed environment sensing information; and a control step of controlling the environment adjustment device based on the generated sleep state information.

METHODS AND SYSTEMS INCLUDING MODULAR BUILD PLATFORMS FOR ADDITIVE MANUFACTURING

Resumen de: US20260208438A1

0000 Systems, methods, and devices for additive manufacturing are provided. In some embodiments, a method includes: coupling a plurality of build platforms to a carrier; forming a plurality of dental appliances on the plurality of build platforms using an additive manufacturing process, where each build platform receives at least one dental appliance thereon; removing the plurality of build platforms from the carrier; performing post-processing of the plurality of dental appliances while the dental appliances remain on the respective build platforms, where the post-processing includes annealing; and separating the plurality of dental appliances from the respective build platforms.

SUPPLEMENT SYSTEM AND DEVICE

Resumen de: US20260207435A1

A system has a base member defining at least one chamber, and a cover cooperating with the base member to enclose the chamber. The cover includes at least one path associated with a respective chamber and positioned to be broken when the cover over the associated chamber is opened. A reader device has a housing sized to mate with a container enclosed by a cover, with the cover supporting a plurality of paths, with each path associated with and extending over each chamber. The reader device has first and second leads associated with a path of a respective chamber, and a controller configured to determine if a chamber is opened or unopened. A membrane for covering at least one chamber of a container is provided with a layer formed from an electrically non-conductive material, and a path formed from an electrically conductive material supported by the layer.

A COMPUTER IMPLEMENTED METHOD AND AN APPARATUS FOR NON-INVASIVE AND EXTRA-CORPORALLY DETERMINING THE ARTERIAL CONCENTRATION OF A RADIOPHARMACEUTICAL, IN PARTICULAR A RADIOTRACER IN AN ORGAN OF AN ANIMAL AND/OR HUMAN BODY

Resumen de: US20260212963A1

0000 The present disclosure relates to a technique to non-invasively and extra-corporeally measure the arterial concentration of a radiotracer administered to animal and/or human bodies or subjects with a radiation detector. In particular a computer implemented method for non-invasive and extra-corporally determining the arterial concentration of a radiopharmaceutical, for example a radiotracer, in an organ of an animal and/or human body is proposed, the computer implemented method comprising the steps of: i) receiving, from the moment of administration of a certain amount of the radiopharmaceutical in the animal and/or human body, by one or more radiation sensors positioned near or on a measurement location of an organ electromagnetic radiation emitted by the radio-pharmaceutical over time; ii) converting the received electromagnetic radiation in a time-sequence of radiation signals; iii) generating one or more time-frequency representations of the radiation signals by time-frequency transformation, and iv) analyzing the time-frequency representations for determining the arterial concentration of the radiopharmaceutical.

DENTAL IMPLANTS WITH CORONAL FEATURES AND SYSTEMS, DEVICES, AND METHODS FOR DESIGNING AND MANUFACTURING SAME

Resumen de: US20260207306A1

Root-analog dental implants include one or more coronal grooves that are sized, shaped, and/or configured to correspond to a size, shape, and/or position of a bone crest for an extracted tooth a root-analog dental implant is designed and manufactured to replace. The coronal grooves may be configured to engage with bone of an alveolar socket to enhance engagement between the root-analog dental implant and the alveolar socket particularly for the time period following seating the root-analog dental implant within the socket site and prior to osseointegration of the root-analog dental implant with the alveolar socket. This promotes stability of the root-analog dental implant within the socket site immediately following insertion and thereafter, which may decrease movement of the root-analog dental implant within the socket site, decrease a likelihood of foreign material such as bacteria or food entering the socket site, and/or reduce a risk of implant failure and jawbone injury.

SINGLE SOURCE-DETECTOR SEPARATION APPROACH TO CALCULATE TISSUE OXYGEN SATURATION

Resumen de: US20260207091A1

0000 A tissue oxygen saturation (StO<2>) parameter is calculated using a single light source and single detector of an optical device, where the light source and detector are separated by a separation distance. A single source-detector separation (SSDS) approach to measure StO<2 >in the tissue of a subject utilizes only intensity measurements of three different wavelengths of light emitted from the same light source (or one or more wavelengths from adjacent one or more light sources) at the detector. In addition to the three intensity measurements, the other inputs to the calculation are a differential pathlength factor (DPF) and extinction coefficients for both oxy-hemoglobin and deoxy-hemoglobin for the given wavelengths. The StO<2 >parameter can be calculated for each distinct source-detector pair of an optical device.

CLOSED-LOOP, NON-INVASIVE BRAIN STIMULATION SYSTEM AND METHOD RELATING THERETO

Resumen de: US20260207959A1

0000 Disclosed herein are a brain stimulation method and system for use on a mammal. The system includes: an electroencephalogram (EEG) headset (110) having sensors for detecting an electrical signal of a patient, and an EEG processing device (120) for determining a stimulation protocol based on that electrical signal. The EEG processing device (120) includes: a brain state inference module (124) for determining an inferred brain state of the patient; and a learning module (126) for learning the stimulation protocol based on the detected electrical signal and the inferred brain state. The system also includes a neuromodulator (130) for delivering stimuli to the patient based on the stimulation protocol.

SYSTEMS AND METHODS FOR ASSESSING SOCIAL SKILLS IN VIRTUAL REALITY

Resumen de: US20260212774A1

0000 Systems and methods provided in this disclosure explain the use of interactive narratives in VR to derive performance metrics for the assessment of individuals'socio-emotional skills. It also provides an explanation of how the change of narrative flow can be configured according to user responses, and how this changing nature of narratives can be used for more valid socio-emotional skills assessment for better prediction of real-life performance in targeted domains.

Beam Filtration Apparatus and Method for Efficient Scanned Beam Particle Arc Therapy

Nº publicación: US20260207971A1 23/07/2026

Solicitante:

UNIV OF IOWA RESEARCH FOUNDATION [US]
University of Iowa Research Foundation

Resumen de: US20260207971A1

0000 A filter for radiation therapy, and other applications, is disclosed. The filter comprises a base and columns of varying heights extending from one face of the base. The column heights are determined by simulating the change in energy distribution of radiation passing through the filter and updating the column heights so as to more accurately match the desired output beam energy distribution. The method of filter design employs an inner loop of faster, but less accurate calculations and an outer loop of slower but more accurate calculations. The column heights for the filter are the last calculated values or the ones which produce the simulated output beam energy distribution which most closely matches the desired output beam energy distribution. The filter can be used in a radiation beam apparatus to treat a patient more quickly.