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Solicitudes publicadas en los últimos 30 días / Applications published in the last 30 days
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COMPOSITIONS AND METHODS FOR ADDITIVE MANUFACTURING OF PALATAL EXPANDERS

NºPublicación:  US20260102224A1 16/04/2026
Solicitante: 
ALIGN TECHNOLOGY INC [US]
US_20260102224_A1

Resumen de: US20260102224A1

0000 Materials, methods, and systems for additive manufacturing are provided. In some embodiments, a method includes: forming a mixture including a first thermoplastic polymer powder separated from a first additively manufactured dental appliance manufactured during a first powder bed fusion process, where the first thermoplastic polymer powder has a characteristic particle size distribution and a characteristic melt volume rate; in a second powder bed fusion process, depositing a powder layer of the mixture, where the powder layer has a powder packing consistency dependent on the characteristic particle size distribution of the first thermoplastic polymer powder; and in the second powder bed fusion process, applying energy to the powder layer to melt the powder layer to form a part layer of a second additively manufactured dental appliance, where the part layer has a material consistency dependent on the characteristic melt volume rate of the first thermoplastic polymer powder.

PRINTER FOR COSMETICS

NºPublicación:  WO2026079532A1 16/04/2026
Solicitante: 
ACTIVON CO LTD [KR]
\uC8FC\uC2DD\uD68C\uC0AC \uC5D1\uD2F0\uBE0C\uC628
WO_2026079532_A1

Resumen de: WO2026079532A1

The present invention relates to a printer for cosmetics that can easily form clear design patterns on the surfaces of cosmetic materials, the printer for cosmetics comprising: a support part for supporting at least one cosmetic material; a header part that includes an ejection port for ejecting an ink composition onto the surface of the cosmetic material and is configured to reciprocate along a first direction; and a first heating part and a second heating part which have the header positioned therebetween and are arranged along a second direction that forms a predetermined angle with respect to the first direction.

DENTAL APPLIANCE, SYSTEM, AND METHOD

NºPublicación:  US20260102223A1 16/04/2026
Solicitante: 
SOLVENTUM INTELLECTUAL PROPERTIES COMPANY [US]
US_20260102223_A1

Resumen de: US20260102223A1

A dental appliance for a patient includes a body including a first surface and a second surface opposite to the first surface. The second surface defines a channel for receiving a plurality of teeth of the patient. The dental appliance further includes an arrangement of a plurality of features disposed on the first surface of the body. Each of the plurality of features includes a protrusion extending from the first surface opposite to the second surface; a depression extending partially from the first surface wards the second surface; or a through-hole extending from the first surface to the second surface. The arrangement of the plurality of features encodes a feature data representative of a dental appliance information of the dental appliance or a patient information of the patient.

METHOD AND APPARATUS FOR NON-INVASIVELY MESAURING BLOOD CIRCULATORY HEMOGLOBIN

NºPublicación:  US20260102066A1 16/04/2026
Solicitante: 
BECTON DICKINSON CO [US]
US_20260102066_A1

Resumen de: US20260102066A1

A method and system for non-invasively determining continuous total hemoglobin data is provided. The method includes a) using a near infra-red spectrophotometric (NIRS) sensing device on a continuous basis to sense a subject's tissue, the sensing producing NIRS signals; and b) determining continuous total hemoglobin (THb) using the produced NIRS signals.

APPARATUS AND METHOD FOR 24-HOUR AMBULATORY BLOOD PRESSURE MONITORING WITH COMPENSATION BASED ON POSTURE AND/OR ACTIVITY DETECTION

NºPublicación:  US20260102067A1 16/04/2026
Solicitante: 
CARDIAI TECH LTD [CA]
US_20260102067_A1

Resumen de: US20260102067A1

0000 An apparatus for monitoring a person's health conditions. The apparatus has one or more biometric sensors for periodically measuring the person's biometric data, one or more activity sensors for periodically measuring the person's activities, and a circuit functionally coupled to the one or more biometric sensors and the one or more activity sensors, the circuit having an artificial intelligence (AI) engine configured for using a trained AI model for analyzing the person's health condition based on the measurement data collected from the one or more biometric sensors and the one or more activity sensors.

SYSTEMS, APPARATUSES, AND METHODS FOR CREATING TISSUE INTERFACES

NºPublicación:  US20260102288A1 16/04/2026
Solicitante: 
SOLVENTUM INTELLECTUAL PROPERTIES COMPANY [US]
US_20260102288_A1

Resumen de: US20260102288A1

A system for creating a tissue interface. The system includes a scanner, at least one processor, and a memory. The scanner is configured to scan a tissue site and generate a signal corresponding to a topography of the tissue site. The at least one processor is configured to receive the signal corresponding to the topography of the tissue site and to receive user input at a user interface identifying a therapy to be applied at the tissue site. The memory is coupled to the at least one processor and is configured to store instructions that when executed by the at least one processor in response to receiving the signal corresponding to the topography of the tissue site cause the system to transform the signal corresponding to the topography of the tissue site into a model site surface and generate a model tissue interface.

SLIDING ELEMENT, METHOD FOR PRODUCING THE SLIDING ELEMENT AND USE OF THE SLIDING ELEMENT

NºPublicación:  WO2026076477A1 16/04/2026
Solicitante: 
AC2T RES GMBH [AT]
WO_2026076477_A1

Resumen de: WO2026076477A1

The invention relates to a sliding element (1), in particular for medical components for use in implantology, comprising a substrate (3) and a biomaterial (2) applied to the substrate (3), which biomaterial provides a sliding layer (1a) on its side facing away from the substrate (3), wherein the substrate (3) has multiple cavities (7) on a connection surface (4) facing the biomaterial (2), wherein the cavities (7) are open in the direction of the sliding layer (1a) and at least 50% of the cavities (7) have an undercut (7a) in the direction of the interior of the substrate (3), wherein the substrate (3), in a first profile depth (a) of at least 0.6 μm, has a round-ridged roughness profile with an areal roughness characteristic Sa of less than 0.05 μm, wherein the substrate (3) has the multiple cavities (7) between the first profile depth (a) and a second profile depth (b), and wherein the second profile depth (b) measures at least 200 μm, preferably at least 350 μm.

METHOD FOR PROVIDING USER INTERFACE FOR MANUFACTURING PROSTHESIS, AND COMPUTER-READABLE RECORDING MEDIUM IN WHICH PROGRAM FOR EXECUTING SAME METHOD ON COMPUTER IS RECORDED

NºPublicación:  WO2026079533A1 16/04/2026
Solicitante: 
IMAGOWORKS INC [KR]
\uC774\uB9C8\uACE0\uC6CD\uC2A4 \uC8FC\uC2DD\uD68C\uC0AC
WO_2026079533_A1

Resumen de: WO2026079533A1

This method for providing a user interface for manufacturing a prosthesis comprises: providing a guide image visualizing the inner surface of a prosthesis to be put on a prepared tooth; providing a parameter adjusting unit for adjusting a plurality of parameters for generating the prosthesis; displaying, on the guide image, a selected parameter image for explaining a parameter selected by a user from among the plurality of parameters; and generating a 3-dimensional image of the prosthesis on the basis of data set by the parameter adjusting unit.

MINIMALLY INVASIVE AND ENDOSCOPIC IN-VIVO BIOPRINTING SYSTEMS AND METHODS

NºPublicación:  AU2025215643A1 16/04/2026
Solicitante: 
PHOSPRINT P C
AU_2025215643_PA

Resumen de: AU2025215643A1

A system (100) may include a donor supply sub-system (110) configured to supply donor material (102) to a donor substrate (104). The system may include a material transfer sub-system (108) comprising a laser (200) configured to illuminate the donor substrate via a transfer beam (202). The system may include an instrument head (302) of a medical instrument (300) configured to house the donor substrate, wherein upon an illumination of the donor substrate, the donor material is transferred to receiver material in vivo.

PREDICTION FUNNEL FOR GENERATION OF HYPO- AND HYPER-GLYCEMIC ALERTS BASED ON CONTINUOUS GLUCOSE MONITORING DATA

NºPublicación:  US20260102124A1 16/04/2026
Solicitante: 
DEXCOM INC [US]
US_20260102124_A1

Resumen de: US20260102124A1

0000 Certain aspects of the present disclosure relate to methods and systems for providing decision support around glucose management for patients with diabetes. Time-varying inputs including blood glucose, meal intake information, and amount of infused insulin are processed using a machine learning model to obtain predicted glucose levels for a plurality of prediction horizons and uncertainties for the predictions. A confidence interval is generated for each prediction and the confidence intervals are compared to hypo- and hyperglycemic thresholds. If a confidence interval is entirely below or entirely above the hypo- and hyperglycemic thresholds, respectively, then a decision support output is provided.

ADJUSTABLE IMPLANT, SYSTEM AND METHODS

NºPublicación:  US20260102187A1 16/04/2026
Solicitante: 
NUVASIVE SPECIALIZED ORTHOPEDICS INC [US]
US_20260102187_A1

Resumen de: US20260102187A1

0000 Aspects of the disclosure relate to an adjustable implant configured to be implanted into a patient that includes an adjustable portion moveable relative to a housing. The adjustable implant may include various smart components for enhancing operation of the implant. Smart components may include a controller for managing operations and a transducer for communicating ultrasound data with an external interface device. Additional smart components may include a load cell within the housing for measuring an imparted load; a sensor for measuring angular position of the adjustable portion; a dual sensor arrangement for measuring imparted forces; a reed switch; a half piezo transducer; and an energy harvester.

OCULAR PHOTO-BIO-STIMULATION OPTICS

NºPublicación:  AU2024337161A1 16/04/2026
Solicitante: 
NEURORAYS LLC
AU_2024337161_PA

Resumen de: AU2024337161A1

A device providing ocular photo-bio-stimulation therapy, a biological technique to control or influence the activity of neurons or other cell types in, on or about the eye with light. As used herein ocular photo-bio-stimulation is an umbrella category of which photobiomodulation, optogenetics and phototherapy are forms thereof. The current invention relates, in part, to photobiomodulation therapy, which includes the utilization of nonionizing electromagnetic energy to trigger photochemical changes within cellular structures. The current invention relates, in part, to optogenetics. Optogenetics is a biological technique to control the activity of neurons or other cell types with light. The current invention relates, in part, to phototherapy, also known as light therapy or bright light therapy, which is a treatment that uses controlled exposure to artificial or natural light to treat medical conditions.

ARTIFICIAL-INTELLIGENCE TECHNIQUES FOR NEUROTOXICITY DETECTION

NºPublicación:  US20260106042A1 16/04/2026
Solicitante: 
NEUROVIGIL INC [US]
US_20260106042_A1

Resumen de: US20260106042A1

Detecting neurotoxicity associated abnormalities due to certain medication therapies can be significant for identifying various neurological disorders. The present disclosure relates to detection of neurotoxicity related disorders by leveraging an interface including one or more sets of queries and a set of components to receive a set of responses corresponding to the sets of queries. The techniques, as disclosed herein, may use one or more attributes of the set of responses including consistency, complexity, grammar and spelling correctness, and time taken during the responses. The disclosed technique may preprocess the responses, extract features and generate one or more metrics corresponding to the one or more attributes of the one or more responses provided by the subject during a session with the interface. The generated metrics over a baseline session and subsequent sessions may be used to determine trends in the metrics which may be used to estimate the extent of neurotoxicity developed by a subject and may trigger an alert about a potential neurotoxicity or a preventative measure to reduce a likelihood of further neurotoxicity.

TREATMENT PLANNING FOR TUMOR TREATING FIELDS

NºPublicación:  US20260102612A1 16/04/2026
Solicitante: 
NOVOCURE GMBH [CH]
US_20260102612_A1

Resumen de: US20260102612A1

A method for generating a transducer layout for delivering tumor treating fields includes storing medical images of a subject, identifying one of the medical images as an anchor medical image, and registering computed tomography medical images with magnetic resonance imaging medical images. The method further includes segmenting abnormal tissue in the medical images from other tissue types and defining a region of interest (ROI) in the medical images. The method further includes creating a 3D model of the subject. The method further includes generating a plurality of transducer layouts for application of tumor treating fields to the subject, selecting at least two of the transducer layouts as recommended transducer layouts, presenting the recommended transducer layouts, receiving a user selection of at least one recommended transducer layout, and providing a report for the selected recommended transducer layout(s).

SYSTEMS AND METHODS FOR SYSTEM AGNOSTIC AUTOMATED DETECTION OF CARDIOVASCULAR ANOMALIES AND/OR OTHER FEATURES

NºPublicación:  US20260105608A1 16/04/2026
Solicitante: 
BRIGHTHEART SAS [FR]
US_20260105608_A1

Resumen de: US20260105608A1

0000 Systems and methods are provided for processing image data generated by a medical imaging system such as an ultrasound or echocardiogram system using artificial intelligence and machine learning to determine a presence of one or more congenital heart defects (CHDs) and/or other cardiovascular anomalies in the image data in a manner that is agnostic to the type of imaging system, software, and/or hardware. Image data from various types imaging systems, software, and/or hardware, having various styles of imaging data generated may be processed to determine image styles. Input image data for analysis may then be processed together with representative styles of image data to generate styled input images for each style. The styled input images may be processed by an image analyzer to detect one or more cardiovascular anomalies in the styled image data, for example. Alternatively, training data may be styled and used to train the image analyzer.

DEVICES FOR PREDICTING DIABETIC STATUS USING VOICE

NºPublicación:  US20260106031A1 16/04/2026
Solicitante: 
KVI BRAVE FUND I INC [CA]
US_20260106031_A1

Resumen de: US20260106031A1

Provided is a computer-implemented device for generating a type-Il (T2DM) diabetic status prediction, including: a memory comprising a diabetic status prediction model; and a processor in communication with the memory, the processor configured to: receive a voice sample from the subject; extract at least one voice biomarker feature value from the voice sample for at least one predetermined voice biomarker feature; determine the type-II (T2DM) diabetic status prediction for the subject based on the at least one voice biomarker feature value and the diabetic status prediction model; and output, to an output device, the type-II (T2DM) diabetic status prediction for the subject or an output based on the diabetic status prediction.

METHOD FOR CALIBRATING AND VERIFYING IMPLANTABLE DETECTING DEVICE, IMPLANTABLE DETECTING DEVICE, APPARATUS, AND ELECTRONIC DEVICE

NºPublicación:  US20260102090A1 16/04/2026
Solicitante: 
SHENZHEN GOOOIX TECH CO LTD [CN]
SHENZHEN GOODIX TECH CO LTD [CN]
CN_119073976_PA

Resumen de: US20260102090A1

0000 A method for calibrating and/or verifying an implantable detecting device, an implantable detecting device, an apparatus, and an electronic device are provided. The method includes: outputting a square wave signal to an implantable detecting device that has been implanted into a subject, where the implantable detecting device is configured to detect a concentration of an analyte in the subject, and a potential of the square wave signal increases incrementally over time; receiving a first current signal produced by the implantable detecting device in response to the square wave signal; generating a calibration curve based on a correspondence between the first current signal and the square wave signal; and performing calibration and/or functional verification on the implantable detecting device based on the calibration curve.

EXAMINING VISIBLE SKIN CONDITIONS

NºPublicación:  AU2025234210A1 16/04/2026
Solicitante: 
SCANSENSOR LTD
AU_2025234210_A1

Resumen de: AU2025234210A1

A method for examining visible skin conditions is shown. A housing (101) is located at a region of a visible skin condition and image data of the skin over this region is captured. Electric fields (2001, 2002) are generated that penetrate the skin over the region, such that an application of the apparatus produces both image-related signals and electric field related signals for the same skin condition. Depth of skin penetration of the visible skin condition may be assessed by calculating the surface area of the visible skin condition from the image data and determining the volume of the visible skin condition from the electric field related signals and processing the calculated surface area in combination with the determined indication of volume to assess the depth of skin penetration. The electric field generating device may comprise a first dielectric substrate (301) having a hole (302) and the capturing step may be performed by a camera (501) viewing the visible skin condition through this hole. A method for examining visible skin conditions is shown. A housing (101) is located at a region of a visible skin condition and image data of the skin over this region is captured. Electric fields (2001, 2002) are generated that penetrate the skin over the region, such that an application of the apparatus produces both image-related signals and electric field related signals for the same skin condition. Depth of skin penetration of the visible skin condition may be assessed by cal

眼科用レンズ及び型内変性によるそれらの製造

NºPublicación:  JP2026512375A 16/04/2026
Solicitante: 
ジョンソン・アンド・ジョンソン・ビジョン・ケア・インコーポレイテッド
JP_2026512375_A

Resumen de: WO2024194792A1

A method for forming an ophthalmic lens including providing a mold assembly including base and front curve molds each having a surface profile and defining and enclosing a cavity therebetween having a reactive monomer mixture for making the lens and a first polymerization initiator that is activated at a first wavelength. A light transmissive one of the molds is exposed to a source of substantially uniform actinic radiation at the first wavelength according to a predetermined exposure pattern including at least one exposure portion and at least one non- exposure portion to initiate polymerization of the reactive monomer mixture within the mold at said at least one exposure portion. The lens is fully cured at the exposure portions and unreacted or non-gelled portions remain within the lens adjacent to the front and base mold halves, which are extracted following removal from the mold assembly, leaving one or more predetermined geometric indentations in the front and back surfaces of the lens such that the surface profile of the lens deviates from the surface profile of the respective front and back mold halves at the locations of the geometric indentations.

COATING FOR METAL ALLOY

NºPublicación:  US20260103781A1 16/04/2026
Solicitante: 
MIRUS LLC [US]
US_20260103781_A1

Resumen de: US20260103781A1

0000 A metal alloy that includes an enhancement coating material. The metal alloy includes rhenium and one or more additives. The enhancement coating is at least partially applied to the metal alloy by a physical vapor deposition (PVD) process, a chemical vapor deposition (CVD) process, an atomic layer deposition (ALD) process, a plasma-enhanced chemical vapor deposition (PE-CVD) process, ion implantation, direct energy deposition (DED), and/or thermal spray techniques like plasma arc spraying, flame spraying, high velocity oxy fuel spraying (HVOF). The enhancement coating is formed of a) 35-95 wt. % zirconium and wherein said enhancement coating includes ZrN, ZrNC, ZrOC or a combination of ZrN and ZrO2, b) 20-85 wt. % titanium and one or more of carbon, nitrogen, oxygen, rhenium, and silicon, c) 40-85 wt. % chromium and one or more of carbon, nitrogen, oxygen, rhenium, and silicon, or d) at least 60 wt. % carbon.

HEART RHYTHM DETERMINATION USING MACHINE LEARNING

NºPublicación:  US20260102139A1 16/04/2026
Solicitante: 
CAPTION HEALTH INC [US]
US_20260102139_A1

Resumen de: US20260102139A1

0000 Circuitless heart rhythm determination can include capturing a video clip of one or more image frames of a target organ through an ultrasound imaging device and submitting the frames to a classifier that has been trained with an annotated set of images, each of a corresponding heart muscle captured at a specified phase of a heart rhythm with a ground truth indication of the specified phase of the heart rhythm drawn from a separately recorded cycle graph of an electrical signal measured over time for the corresponding heart muscle. In response to the submission, a classification can be received of different portions of the submitted frames according to corresponding phases of the heart rhythm. Finally, a contemporaneous phase of the heart rhythm can be determined in the device without sensing electrical signals by way of a closed-loop sensor circuit affixed proximately to the target heart muscle.

METAL OXIDE BIOLOGICAL IONOMER AND METHODS

NºPublicación:  US20260102509A1 16/04/2026
Solicitante: 
BUTZLOFF PETER [US]
US_20260102509_A1

Resumen de: US20260102509A1

A nanoparticle compound comprising buckminsterfullerene C60 bonded to ester functional groups of pyruvic, citric, and hyaluronic acids, with oxygen-bridged components selected from vanadium, gallium, and bismuth is provided. At least one component enables quantum-mechanical spin-wave activation. Ultrasonic irradiation activates the compound, inducing electrical induction for tissue healing and cell growth. The compound integrates with native and 3D-printed tissues, enhancing their properties through interpenetrating networks. It exhibits anti-inflammatory, antioxidant, and antibacterial effects, reinforces connective tissue, and modulates stem cell growth. The compound treats arthritis, enhances gut health and barrier function, supports bone health, improves voice quality, counters cancer cell proliferation, and mitigates osteoporosis. The gallium component creates an alkaline environment for calcium deposition, while vanadium enhances chondrogenic differentiation. Administration methods include topical application, oral ingestion, injection, and infusion through bandages or sutures. The compound serves as an adjuvant for analgesics, enhancing their delivery and efficacy.

SYSTEMS AND METHODS FOR BIOPRINTING CORNEAL STROMA EQUIVALENTS

NºPublicación:  WO2026078545A1 16/04/2026
Solicitante: 
NEW YORK UNIV IN ABU DHABI CORPORATION [AE]
WO_2026078545_A1

Resumen de: WO2026078545A1

Synthetic corneal stroma are created though a bioprinting process. The bioprinting process utilizes Digital Light Processing (DLP) in the formation of the corneal stroma. A hydrogel is formed to serve as the basis for the DLP printing. The DLP printing process provides control exposure of the hydrogel to UV light. The bioprinting through the DLP printing process forms a synthetic corneal stroma.

3D SCANNING METHOD, SYSTEM AND APPARATUS FOR DENTAL APPLICATIONS

NºPublicación:  US20260102230A1 16/04/2026
Solicitante: 
SALLOUM RAMI [US]
US_20260102230_A1

Resumen de: US20260102230A1

A method and device for aligning face scans with intraoral scans in dentistry applications. Digital intraoral scans capture the upper and lower arches and a bite registration. An Anterior Extension Device is affixed in the patient's mouth. A working scan of the upper arch scan is trimmed to remove the areas covered by the Anterior Extension Device. A rigid reference link extends between the Anterior Extension Device and base of the patient's nose. The working scan is rescanned to include the Anterior Extension Device and rigid reference link and patient's nose. A facial scan is taken while the patient is smiling. The rescanned working scan is aligned and merged with the facial scan on the basis of at least three points of reference on the patient's nose. A prosthetic device is designed using in combination the intraoral scans aligned with the facial scan.

NOVEL 3D PRINTING SELF-STABILIZING CERVICAL INTERBODY FUSION CAGE

Nº publicación: US20260102258A1 16/04/2026

Solicitante:

THE THIRD HOSPITAL OF CHANGSHA [CN]

US_20260102258_A1

Resumen de: US20260102258A1

0000 A novel 3D (three-dimensional) printing self-stabilizing cervical interbody fusion cage is provided, including a fusion cage body, circular-arc notches arranged at four corners of a front side surface of the fusion cage body, and threaded openings are formed in interiors of the circular arc notches and screws are correspondingly mounted in the threaded openings. An inner wall of the fusion cage body is of a circular arc structure, and a reserved circular opening is formed in the middle position of the front side surface. Each of the circular arc notches is positioned to form an angle of 45° with a horizontal plane of each of the four corners of the fusion cage body. Screw are self-tapping screws with threads, and the threads of the screws are in fit with threads of the inner walls of the circular arc notches.

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