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用于标记医疗设备的标记物位置的方法及医疗设备

Resumen de: CN122440333A

本文中讨论了一种医疗设备，其包括用于标记所述医疗设备的标记物位置的标记物（100），所述医疗设备包括：所述医疗设备的管；不透射线的标记材料（100），其用于标记所述医疗设备的标记物位置；并且其中所述不透射线的标记材料（100）通过增材制造在流体中从所述医疗设备的标记物位置处添加到所述管上，从而形成固体不透射线的标记物（100），以用于增加所述医疗设备在径向方向（R）上的X射线不透性。特别地，管可以包括编织和/或盘绕的丝网（210）的纤维，并且该方法包括用标记材料固定编织和/或盘绕的丝网（210）的纤维的步骤。

用于复杂牙列患者的3D打印树脂颌叉固定方法及系统

Resumen de: CN122442951A

本发明公开了用于复杂牙列患者的3D打印树脂颌叉固定方法及系统，涉及口腔数字化修复技术领域，包括获取牙列患者的口内扫描数据，基于牙尖嵌合轨迹提取下颌牙列支撑点、倒凹锁定区及动态咬合干扰边界，建立带承托稳定性权重和运动避让约束的下颌全牙列及咬合关系的三维数字模型，并根据扫描面弓、咬合记录仪和下颌金属颌叉的接口规格进行坐标统一和装配间隙匹配，得到初步对接特征集；该用于复杂牙列患者的3D打印树脂颌叉固定方法及系统，提高复杂牙列患者咬合记录和下颌运动分析的准确性、重复性及临床操作效率。

一种CAD/CAM舌侧牙槽骨增量联合骨皮质切开导板及其制作方法

Resumen de: CN122440340A

本发明公开了一种CAD/CAM舌侧牙槽骨增量联合骨皮质切开导板，包括用于辅助上颌牙正畸的上颌导板和用于辅助下颌牙正畸的下颌导板；上颌导板包括上导板定位部和上导板体部，在上导板体部前侧一体化设置有上导板定位部，上导板定位部贴合扣紧在上颌牙上、使上导板体部贴合设置在上颌骨腭部；下颌导板包括下导板体部、下导板定位部和导板舌挡部，在下导板体部前侧一体化设置有下导板定位部、后侧一体化设置有导板舌挡部。制作方法包括：步骤一、获取数字化三维模型；步骤二、数字化导板设计。该发明保证了手术中植骨范围的准确性和植骨量的充分性，填补了舌侧术式的空白，推动了舌侧骨增量联合骨皮质切开术的广泛推广与规范化应用。

用于牙齿和骨骼的植入物

Resumen de: WO2025102118A1

The present disclosure relates to implants for teeth and bone. The implants are prepared from a polymer of the poly (aryl ether ketone) family, preferably poly ether ketone (PEK), and are activated with plasma to improve integration with teeth and bone. Methods and kits related to use of the implants are also disclosed.

コア－シェル構造を有する細胞スフェロイドを自動的に生成する新規方法

Resumen de: WO2025024235A1

Provided herein are methods of producing spheroids from one or more cells, in a pipette tip. The spheroids may comprise a single cell type, or multiple cell types. Also provided are methods of using the spheroids in fully or partially automated assays, high-throughput screening, and clinical application.

知的自動体外授精及び細胞質内精子注入プラットフォーム

Resumen de: US2024423673A1

0000 A method for automated ICSI includes receiving at least one droplet containing an egg in a dish placed on a stage. The method includes using an artificial intelligence/machine learning system (AI/ML system) and an imaging system to detect a zona pellucida. The imaging system includes a microscopy system, a camera system, and a lighting system. The method includes holding the egg using a robotic microtool and lowering a robotic pipettor into the droplet. The method includes using the AI/ML system and imaging system to determine an area at which to hold the egg and positioning the robotic microtool to that area. The method includes using the AI/ML system and imaging system to instruct the robotic microtool to apply negative pressure to hold the egg to the robotic pipettor. The method includes using the AI/ML system and imaging system to determine a target location where zona ablation should be performed.

一种高强度的细菌矿化仿生骨支架及其制备方法

Resumen de: CN122440900A

本发明提供了一种高强度的细菌矿化仿生骨支架及其制备方法，该制备方法通过在水凝胶前体溶液中加入矿化细菌，利用3D打印制备具有精细宏观结构的水凝胶支架，后将该支架浸泡于含有尿素和矿物盐的矿化细菌培养液中，使细菌进行原位矿化，在微观尺度上形成由微米级矿化颗粒组成的三维网络，实现对天然骨组织的精确仿生。该制备方法具有能耗低、适用于工业化生产和低经济成本的优点。本发明的方法不仅显著提升了支架的力学性能，还优化了骨修复过程中所需的生理微环境，为骨组织再生提供了更加理想的生理基础。制得的仿生骨支架表现出优异的力学性能，压缩模量高达12.05MPa，并具有优异的良好的生物相容性和成骨活性。

POLYFUNCTIONAL DENTAL DEVICES AND ASSOCIATED METHODS

Resumen de: US20260207305A1

0000 A series (100) of devices for incrementally changing the tooth position of a person (P), comprising at least two devices (10), is explained, wherein the devices (10) each comprise at least one jaw device (11, 12), wherein the at least one jaw device (11, 12) is designed such that receiving regions of the jaw device (11, 12) may be placed onto a dental arch of the upper jaw (OK, 5) or the lower jaw (UK, 4) of the person (P), wherein the devices (10) are designed to provide, when worn according to a predetermined sequence of the devices (10), an incrementally progressive change in tooth position by mechanical interaction of the device and at least one tooth element. 0000 The at least one jaw device (11, 12) of the first device (10.1, 10.2) may carry a first veneering element (N.I.1.2, N.IV.1.2) on its outer side as a partial area of the first device (10.1, 10.2). The at least one jaw device (11, 12) of the second device (10.n ) may carry a second veneering element (N.I.1.n, N.IV.1.n ) on its outer side as a sub-region of the second device (10). The first veneering element (N.I.1.2, N.IV.1.2) may be located at the same position according to a tooth scheme as the second veneering element (N.I.1.n, N.IV.1.n ). A receiving regions of the first veneering element (N.I.1.2, N.IV.1.2) may be designed differently and/or have a different position than a receiving element of the second veneering element (N.I.1.n, N.IV.1.n ), this difference being suitable for effecting

METHODS AND SYSTEMS INCLUDING MODULAR BUILD PLATFORMS FOR ADDITIVE MANUFACTURING

Resumen de: US20260208438A1

0000 Systems, methods, and devices for additive manufacturing are provided. In some embodiments, a method includes: coupling a plurality of build platforms to a carrier; forming a plurality of dental appliances on the plurality of build platforms using an additive manufacturing process, where each build platform receives at least one dental appliance thereon; removing the plurality of build platforms from the carrier; performing post-processing of the plurality of dental appliances while the dental appliances remain on the respective build platforms, where the post-processing includes annealing; and separating the plurality of dental appliances from the respective build platforms.

REAL TIME MANAGEMENT OF DATA RELATING TO PHYSIOLOGICAL CONTROL OF GLUCOSE LEVELS

Resumen de: US20260211903A1

Integrated glucose monitoring systems, comprising a memory configured to store data relating to at least two glucose measurements of a user, a glucose safe range, and exogenous data. Wherein the at least two glucose measurements of the user are at different time points t1 and t2; a user interface comprising a display; and a processor comprising computer-executable instructions. Wherein the computer-executable instructions determine a rate of change based on the at least two glucose measurements of the user; determine, based on the at least two glucose measurements of the user and the determined rate of change, a projected glucose level at a future time t3; and provide an alarm at the user interface if, based on at least one point of exogenous data, the projected glucose level at future time t3 is outside of the glucose safe range.

CURABLE COMPOSITION FOR THREE-DIMENSIONAL STEREOLITHOGRAPHY, METHOD FOR PRODUCING SAME, METHOD FOR PRODUCING THREE-DIMENSIONAL STEREOLITHOGRAPHIC PRODUCT, AND METHOD FOR PRODUCING DENTAL RESTORATION ARTICLE

Resumen de: AU2024424532A1

Provided are: a curable composition for three-dimensional stereolithography, which contains 100 parts by mass of a polymerizable monomer component (A), 40-400 parts by mass of an inorganic filler (B), 0.01-5 parts by mass of a photoinitiator (C), and 0.01-2.5 parts by mass of an activation light absorber (D), and in which 10-90 mass% of the inorganic filler (B) is contained as an organic-inorganic composite filler (E), the value of light scattering index Sc serving as an index of the proportion of light scattered laterally when being irradiated with activation light is 10% or less, and the rate of transmission for activation light in a state prior to being optically cured is 1-50%; and a method for producing the curable composition for three-dimensional stereolithography. The present invention also provides a method for producing a three-dimensional stereolithographic product and a method for producing a dental restoration article, in both of which said curable composition for three-dimensional stereolithography is used.

MEDICAL DEVICE HUB POSITION DETECTION SYSTEM, METHOD, AND APPARATUS

Resumen de: AU2024415223A1

A system, method, and apparatus are disclosed for determining positions of medical devices within a hub, which comprises a number of apparatuses that are linked together in a stacked configuration. A medical device hub includes a connectivity apparatus that is communicatively coupled to a medical network and/or a monitoring device. Additionally, the medical device hub includes one or more docking apparatuses. Each docking apparatus can accommodate two or more infusion pumps. The number of docking apparatuses used in the medical device hub depends on the number of infusion pumps needed for a patient treatment. The medical device hub enables multiple docking apparatuses to be stacked as needed while enabling the infusion pumps to be operated independently and removed from the medical device hub as needed, even during a treatment without interruption. Such a configuration provides a scalable, flexible, and adaptable system that aggregates infusion pumps into a relatively small footprint.

METHOD FOR INDUCING 3D CELL REPROGRAMMING USING HYALURONIC ACID-BASED HYDROGEL

Resumen de: WO2026155403A1

The present invention relates to a method for inducing 3D cell reprogramming using a hyaluronic acid-based hydrogel, and provides a method for inducing cell reprogramming of adult cells, the method comprising the steps of: preparing a hydrogel solution containing hyaluronic acid and a polymer; suspending adult cells in the hydrogel solution; encapsulating the adult cells by solidifying the hydrogel solution in which the adult cells are suspended; and culturing or injecting into a body the adult cells encapsulated in the hyaluronic acid-based 3D hydrogel.

INTEGRATED MEDICAL IMAGING

Resumen de: WO2026154359A1

Presented herein are methods and systems for integrating pre-operative and post-operative images of a subject to create an enhanced image. According to one aspect, a method includes obtaining a first image at a first time and obtaining second image at a second time. The first image is a three-dimensional (3D) image and the second image is a two-dimensional (2D) image. The method also includes determining a view angle associated with the first image. The view angle is associated with a 2D projection of the first image and is arranged to match the 2D projection with the second image. Matching the second image with the 2D projection includes extracting a feature from the first image and projecting the feature at the view angle onto a 2D plane to form a projected feature. The projected feature is transferred to the second image to create an enhanced second image.

SYSTEM AND METHOD FOR ANALYSIS OF ENDOSCOPIC IMAGING

Resumen de: WO2026156359A1

A system and method for artificial intelligence (AI)-assisted medical diagnostics. A real-time endoscopic ultrasound (EUS) video stream of a patient's organ, such as the pancreas, is received at a computing device. The EUS video stream comprises a plurality of imaging modalities, including at least grey-scale data and elastography data representing tissue stiffness. One or more processors execute an AI model, which processes the video stream to identify, segment, and characterize a region of interest. A visual output is generated for display on a user interface in real-time, the output comprising the EUS video stream with a graphical overlay that includes a visual indicator delineating the segmented region and a classification label corresponding to the characterization, thereby providing real-time clinical decision support.

ELECTRONIC DEVICE FOR PROVIDING NOTIFICATION OF DEGENERATIVE DISEASE, OPERATION METHOD THEREOF, AND STORAGE MEDIUM

Resumen de: WO2026155442A1

According to one embodiment, when executed by at least one processor of an electronic device, instructions are configured to instruct, in a non-transitory storage medium for storing computer-readable instructions, the electronic device to perform at least one operation, wherein the at least one operation can include the operations of: connecting to a wearable electronic device; identifying first sensing data acquired from the wearable electronic device and accumulated during a first period from among sensing data measured by a plurality of sensors of the wearable electronic device; identifying that, from among a plurality of conditions related to a degenerative disease, a first condition in which a change amount of the first sensing data exceeds the threshold value during the first period is satisfied; identifying, on the basis of the identification that the first condition is satisfied, second sensing data measured by the plurality of sensors of the wearable electronic device during a second period and acquired from the wearable electronic device; identifying, on the basis of the second sensing data, that a second condition from among the plurality of conditions is satisfied; and displaying, on the basis of the identification that the second condition is satisfied, a notification of the degenerative disease corresponding to the first condition and the second condition.

APPROACHES TO CHARACTERIZING PATIENT MOBILITY THROUGH ANALYSIS OF PRESSURE-MITIGATION DEVICE USAGE

Resumen de: WO2026156278A1

Introduced here are approaches to gleaning insights into patient mobility through the analysis of usage of pressure-mitigation systems (or simply "systems"). A system can include one or more controller devices (or simply "controllers") and one or more pressure-mitigation devices, each of which includes a series of selectively inflatable chambers. When a pressure-mitigation device is placed between a living body and an object, a controller can circulate fluid through the chambers of the pressure-mitigation device to shift the force that is applied by the object to the living body. Insights can be gleaned through analysis of usage of pressure-mitigation devices by patients. For example, if a pressure-mitigation device is deployed on a surface of an object and a patient is situated thereon, insights into mobility of the patient can be gleaned by monitoring usage of the pressure-mitigation device, and these mobility insights may lead to insights into health of the patient.

METHOD FOR SEGMENT-BY-SEGMENT PARAMETER ASSIGNMENT TO A COMPONENT, METHOD FOR GENERATING MANUFACTURING DATA USING A METHOD OF THIS TYPE, AND PRODUCTION OF A COMPONENT USING MANUFACTURING DATA OF THIS TYPE

Resumen de: WO2026154085A1

The invention relates to a method for segment-by-segment parameter assignment to a component, comprising the steps of: a) reading a three-dimensional component dataset describing a geometry of a component, which describes the component by means of three-dimensional data of a surface of the component, into a computer; b) virtually segmenting the component dataset into multiple component portions, and assigning the segmented component portions to one type of at least two different component portion types by means of a computing model formed by machine learning; wherein by means of the computing model, c) a first parameter is assigned to a first component portion of the multiple component portions. The invention is characterized in that the assigning of the first parameter in step c) is a computer-assisted determination of a first wall thickness in the region of the first component portion from data of the component data set describing the first component portion.

APPLICATOR FOR SUBCUTANEOUS ANALYTE SENSOR INSERTION

Resumen de: WO2026154352A1

A subcutaneous analyte sensor applicator is provided. The applicator includes a lancet, an ortho-planar insertion spring and a sensor. The lancet disposed within a housing configured to travel along a strike path. The ortho-planar insertion spring configured to interact with the lancet and to extend from a relaxed planar form to an extended three-dimensional firing form having energy stored therein to drive the lancet along the strike path. When in the relaxed planar form the ortho-planar insertion spring resides in a plane that is substantially normal to the strike path of the lancet. When in the extended three-dimensional firing form the ortho-planar insertion spring is extended in a third/height dimension that extends along the strike path. The sensor is electronically and/or communicatively coupled with sensor electronics for determining an analyte within the body of a user.

ROBOTIC SURGERY SYSTEM WITH DYNAMIC DIGITAL TWIN AND MULTIMODAL TISSUE ANALYSIS

Resumen de: US20260207281A1

A robotic surgical system is disclosed that integrates a simulation module, artificial intelligence (AI), and a multimodal sensor array to enhance intraoperative decision-making and execution. The system generates a dynamic, patient-specific digital twin representing anatomical, physiological, and thermal data, continuously updated during surgery. Real-time sensor inputs, including force feedback, imaging, and biomarkers, are analyzed by an AI module to characterize tissue conditions, predict responses, and guide tool trajectories. The system adapts tool movement based on AI confidence scoring, margin proximity, and predictive modeling. A visualization interface overlays augmented insights onto live surgical views. The platform enables surgeon-specific and population-based learning, real-time feedback, and intraoperative handoff based on biometric or performance indicators. Embedded modules provide simulation, planning, deviation tracking, and control adjustment. This system supports autonomous, semi-autonomous, or surgeon-guided operation, promoting improved precision, safety, and outcomes across diverse surgical specialties.

SYSTEM FOR MONITORING BODY CHEMISTRY

Resumen de: US20260207085A1

A system and method for monitoring body chemistry of a user, the system comprising: a housing supporting: a microsensor comprising a first and second working electrode, a reference electrode, and a counter electrode, and configured to access interstitial fluid of the user, and an electronics subsystem comprising a signal conditioning module that receives a signal stream, from the microsensor, wherein the electronics subsystem is configured to detect an impedance signal derived from two of the first working electrode, the second working electrode, the reference electrode, and the counter electrode; and a processing subsystem comprising: a first module configured to generate an analysis indicative of an analyte parameter of the user and derived from the signal stream and the impedance signal, and a second module configured to transmit information derived from the analysis to the user, thereby facilitating monitoring of body chemistry of the user.

SYSTEMS AND METHODS FOR VASCULAR HEALTH ASSESSMENT USING ACOUSTIC ANALYSIS AND MACHINE LEARNING

Resumen de: WO2026156287A1

A method is provided. The method comprises receiving acoustic data from at least one transducer device positioned proximate to an artery. The method comprises processing the received acoustic data using signal analysis techniques. The processing comprises generating frequency domain representations of the acoustic data. The method comprises partitioning the frequency domain representations into a plurality of frequency bins. The method comprises analyzing the frequency domain representations using at least one machine learning model. The analyzing comprises determining a degree of arterial stenosis based on the frequency domain representations. The method comprises outputting an indication corresponding to the determined degree of arterial stenosis. The frequency domain representations may be generated using a frequency domain analysis of the acoustic data. The at least one machine learning model may be trained using a dataset comprising acoustic recordings associated with known stenosis levels.

GUIDED REPORT INTERPRETATION USING LARGE LANGUAGE MODEL

Resumen de: WO2026154424A1

Systems and methods for generating a report interpretation summary include receiving a request to generate a summary for test data associated with gastric activity of a patient over a predetermined time period, where the electrical signals are measured with an electrode array patch disposed over a skin surface of the patient, and identifying a plurality of sections to be included in the summary. Systems and methods further include, for each section in the plurality of sections, constructing a prompt for the section based upon a prompt template and rule-based logic configured for the section, providing the prompt as input to an LLM, and responsive to the providing, generating by the LLM a summary for the section. Systems and methods further include generating an overall summary that includes the summaries generated for the plurality of sections and performing a set of one or more validation checks to check contents of the overall summary.

TOTAL ANKLE REPLACEMENT WITH GRADIENT POROUS STRUCTURE

Resumen de: US20260207342A1

A gradient porous structure for one or more bone contacting surfaces of a total ankle replacement implant is provided. The gradient porosity of the porous structure may be optimized to match the natural variation of a patient's bone density, while the pattern of the porous structure may be optimized to maximize mechanical strength so that the implant is structurally stable within the ankle joint.

DNA FINGERPRINT SCANNER AND AUTHENTICATOR

Nº publicación: WO2026156384A1 23/07/2026

Solicitante:

WHITFIELD ROBERT [US]
WHITFIELD, Robert

Resumen de: WO2026156384A1

Systems, apparatuses, and methods provide for processing for DNA fingerprint scanner systems. Such a DNA fingerprint scanner includes a body fluid DNA sampler, a printed DNA sampler, and a DNA analyzer. The body fluid DNA sampler is to receive body fluid. The printed DNA sampler is to sample a printed DNA infused fingerprint certificate. The DNA analyzer is coupled to the body fluid DNA sampler and the printed DNA sampler. The DNA analyzer is to determine DNA sequencing of the body fluid and the printed DNA infused fingerprint certificate.