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TRANSCATHETER DELIVERABLE PROSTHETIC HEART VALVES

Resumen de: EP4516266A2

A prosthetic valve includes a frame and a flow control component. The frame has an aperture extending through the frame about a central axis. The flow control component is mounted within the aperture and is configured to permit blood flow in a first direction approximately parallel to the vertical axis from an inflow end to an outflow end of the flow control component and to block blood flow in a second direction, opposite the first direction. The frame has an expanded configuration with a first height along the central axis, a first lateral width along a lateral axis perpendicular to the central axis, and a first longitudinal length along a longitudinal axis perpendicular to the central axis and the lateral axis. The frame has a compressed configuration with a second height less than the first height and a second lateral width less than the first lateral width.

DEVICE AND METHOD FOR MARKING EDIBLE OBJECT

Resumen de: EP4403363A2

An edible-body marking device (1) has a carrier device (20) that carries an edible body, a detection part (210) that detects the edible body, and a laser processing part (220) that forms a marking pattern on the edible body by using laser light. The carrier device sequentially carries the edible body to the detection part (210) and the laser processing part (220). The detection part images (210) the edible body to acquire orientation information regarding an orientation of the edible body, and the laser processing part (220) has a memory part that stores in advance multiple pieces of marking procedure information regarding formation procedures of the marking pattern in association with their respectively different pieces of the orientation information, and forms the marking pattern on the edible body according to the marking procedure information extracted from the memory part based on the orientation information acquired by the detection part (210).

BENDABLE TITANIUM-ALLOY IMPLANTS

Resumen de: AU2022455175A1

An implantable device (2) includes a portion that is constructed such that at least a majority of the portion, as measured by volume, comprises Ti64 (Ti-6AI-4V) alloy. Additionally, the portion is bendable to a bend angle of at least about 50 degrees about a bend axis while maintaining structural integrity.

METHOD FOR PRODUCING AN IMPLANT AND IMPLANT

Resumen de: EP4516428A1

Die Erfindung bezieht sich auf ein Verfahren zur Herstellung eines Implantats (1), wobei das Implantat wenigstens zwei miteinander verbundene Bauteilabschnitte (1a, 1b, 1c) aufweist, die wenigstens in einem Bereich (1d), in dem sie aneinander angrenzen, durch ein additives Fertigungsverfahren in Form eines Pulverbett-Verbindungsprozesses hergestellt werden, wobei ein erster Bauteilabschnitt (1a) aus einem ersten Material und ein zweiter Bauteilabschnitt (1b) aus einem zweiten Material hergestellt wird, wobei das erste und das zweite Material sich durch das Maß ihrer Bio-Kompatibilität unterscheiden. Das additive Herstellungsverfahren ermöglicht dabei eine sehr freie Gestaltung der verschiedenen Bauteilabschnitte des Implantats.

ARTIFICIAL ANTERIOR TOOTH FOR NATURALISTIC APPEARANCE

Resumen de: AU2022456714A1

An artificial anterior tooth having a more naturalistic or lifelike appearance for use in the design and/or production of a dental prosthesis and/or dental restoration is provided. The lingual-facing surface of an artificial anterior tooth is provided with a plurality of furrows in predetermined locations on the lingual-facing surface to correspond with a plurality of furrows on the labial-facing surface in predetermined locations on the labial-facing surface, so as to impart variable, lifelike color and/or translucency properties throughout the tooth.

HOLLOW EMBOLIC MICROSPHERE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF

Resumen de: EP4516327A1

A hollow embolic microsphere, a preparation method therefor, and a pharmaceutical composition and use thereof, wherein: the hollow embolic microsphere is a microsphere prepared by using a polymer material and having a unique shape and structure, and is suitable for transcatheter arterial embolization. The hollow embolic microsphere of the present disclosure can enter channels having different sizes, and has good embolization effects on various target positions. The hollow microsphere is internally porous and has drug loading abilities, and drug release when loading drug can be easily controlled and the treatment effect is good. No emulsifier or surfactant is needed in the preparation of the hollow microsphere, reaction conditions are mild, and the process is simple. The obtained microsphere has a uniform shape and a controllable size, and is capable of controlling the embolization time. Various drugs including protein heat-sensitive drugs can be loaded, and the drug encapsulation efficiency can reach more than 70%.

一种利用3D打印技术制作的腕关节伸直功能康复支具

Resumen de: CN222549566U

本实用新型提供一种利用3D打印技术制作的腕关节伸直功能康复支具，涉及康复支具技术领域，包括护具、托具、条板和支撑件。该腕关节伸直功能康复支具，在手腕康复过程的每个阶段都需要调整腕关节弯曲角度，适应患者康复的特定需求，拉动短滑杆，使短滑杆沿着内滑槽进行滑动，拉动长滑杆，可以使得长滑杆沿着外滑槽进行滑动，使得支撑件的倾斜角度发生变化，改变了托具的倾斜角度，起到调节腕关节弯曲角度的作用，双边波浪形的内外滑槽，增大长滑杆和短滑杆移动的阻力，提高支撑件固定稳定性，在遇到调节护具和托具之间的角度，但是支撑件长度不够无法达到预定的角度的问题时，将支撑件取出，拧动支撑件中的螺纹筒和螺纹杆，使支撑件长度变长。

一种具有智能响应性的3D打印植物基蛋白双凝胶及其制备方法

Resumen de: CN119547846A

本发明提供了一种具有智能响应性的3D打印植物基蛋白双凝胶及其制备方法，所述蛋白双凝胶包括水溶凝胶组合物及油溶凝胶组合物，所述水溶凝胶组合物包括植物蛋白、水、水溶性营养物及水溶性指示剂，所述油溶凝胶组合物包括油凝胶剂、植物油、脂溶性营养物及脂溶性指示剂。本发明所述的具有智能响应性的3D打印植物基蛋白双凝胶通过油凝胶剂与水凝胶剂之间的相互作用构建稳定的蛋白双凝胶体系，具有良好的机械稳定性，将多种营养元素富集于同一产品中，提高了产品的营养价值，蛋白双凝胶还具有良好的3D打印适应性及灵敏的外界环境刺激响应性，利用产品的感官特性反馈产品在不同的加工保藏过程营养物的变化，实现产品的营养价值的可视化监测。

后咬合干扰元件

Resumen de: WO2024201382A1

The present disclosure discusses techniques for fabricating bite interference elements within polymeric dental appliances. The techniques disclose at least one polymeric shell that includes a number of cavities shaped to fit over a patient's teeth. The polymeric shell includes an occlusal appliance surface shaped to fit over an occlusal tooth surface of the patient. One or more bite interference elements are formed within the occlusal appliance surface, and each bite interference element includes a partially disc-shaped feature extending radially away from the occlusal tooth surface when worn by the patient.

无机结构体及无机结构体的制造方法

Resumen de: WO2024019059A1

Provided are an inorganic structure including portions differing in mechanical property and a method for producing the inorganic structure. An inorganic structure (1) as an embodiment of the present invention comprises a plurality of solidified portions (SA) made of an inorganic material. The plurality of solidified portions (SA) comprise a first solidified portion (SA1), in which the material has been oriented preferentially in a first crystallographic orientation (CO1), and a second solidified portion (SA2), in which the material has been oriented preferentially in a second crystallographic orientation (CO2), which differs from the first crystallographic orientation (CO1).

基于TPMS结构的3D打印骨支架及其制备方法和应用

Resumen de: CN119548670A

本发明提供一种基于TPMS结构的3D打印骨支架，该骨支架以Ti‑6Al‑4V粉末为建筑原料，通过3D打印方式制备，骨支架为TPMS的G单元结构，孔径范围为420～630μm，内层孔隙率为55％，外周孔隙率为90％，支架直径15mm，高2mm。在骨支架的内部装载莫西沙星/利福平PLGA微球和BMP‑2，并用水凝胶固定，就形成基于TPMS结构的3D打印抗感染骨支架。所制备的3D打印抗感染骨支架在各个方面均凸显了优异的性能，具有良好的抗感染和促进骨形成的能力，为感染性骨缺损的治疗提供了一种新的材料和思路。此外，还公开了该支架的制备方法和应用。

一种3D打印聚合物前驱体仿生墨鱼骨陶瓷支架及其制备方法与应用

Resumen de: CN119551977A

本发明涉及一种3D打印聚合物前驱体仿生墨鱼骨陶瓷支架及其制备方法与应用。所述3D打印聚合物前驱体仿生墨鱼骨陶瓷支架的制备方法包括以下步骤：(1)将聚合物前驱体与光敏树脂混合，得到打印浆料；(2)利用3D建模软件设计支架结构为仿生墨鱼骨结构，并将所述打印将浆料进行3D打印，打印完成后进行清洗、二次固化，得到仿生墨鱼骨陶瓷支架坯体；(3)将所述仿生墨鱼骨陶瓷支架坯体进行烧结以产生化学反应生成镁黄长石相，得到所述3D打印聚合物前驱体仿生墨鱼骨陶瓷支架。

用于胰岛移植的3D打印柔韧性水凝胶器件及其制备方法和应用

Resumen de: CN119552304A

本发明提供用于胰岛移植的3D打印柔韧性水凝胶器件及其制备方法和应用，通过开发含有N‑丙烯酰基脲胺和羧酸甜菜碱脲基丙烯酸酯的功能性墨水，并采用数字光处理3D打印技术，优化墨水配方和打印参数，制备出具有优良柔韧性、生物相容性和可控孔隙结构的用于胰岛移植的3D打印柔韧性水凝胶器件。该器件通过DLP打印技术逐层构建水凝胶器件的复杂几何结构，实现了对器件孔隙率、尺寸及形状的精确控制；所制备的水凝胶器件能够显著改善胰岛细胞移植后的微环境，提供有效保护，提升胰岛细胞的存活率和移植成功率。

一种椎间融合器的激光打印方法及椎间融合器

Resumen de: CN119548293A

本发明公开了一种椎间融合器的激光打印方法及椎间融合器，涉及医疗器械领域。该椎间融合器的激光打印方法包括：建立包括中间体模型、椎间融合器模型及虚连接层的打印模型；根据打印模型建立激光打印参数，其中，虚连接层对应的激光输入的能量密度区别于中间体模型及椎间融合器模型对应的能量密度；根据激光打印参数进行打印，得到打印结构；施加作用力破坏各个椎间融合器与中间体之间的虚连接体，以拆除中间体，得到多个椎间融合器。本发明提供的椎间融合器的激光打印方法能够显著提升椎间融合器的制备效率，降低制备成本。

一种数字化设计Twin block的系统、介质及方法

Resumen de: CN119550627A

本发明公开了一种数字化设计Twin block的系统包括：牙齿模型导入程序模块、倒凹程序模块、钢丝模型生成程序模块、合垫模型生成程序模块、导斜面生成程序模块、解剖面生成程序模块、包围盒模型生成程序模块、卡槽生成程序模块和输出程序模块，一种数字化设计Twin block的方法，实现了数字化设计带合垫包围盒的上下颌模型，直接3D打印模型，安装钢丝之后可以直接铺设树脂基托，等待树脂基托凝固之后拆除合垫包围盒就完成了Twin block的制作，简单高效且无需繁琐的上颌架的过程。

一种基于3D打印的液体硅胶增材制造定制式早期矫治器

Resumen de: CN119548265A

本发明涉及矫治器技术领域，具体地说，涉及一种基于3D打印的液体硅胶增材制造定制式早期矫治器，包括上咬合套和下咬合套，上咬合套的上部设有用于供上颌牙齿插入的上齿槽，上咬合套的上部且位于外侧相对设有唇颊屏，唇颊屏可沿上咬合套周向移动设置，上咬合套的上部且位于内侧设有舌抵，下咬合套的下部设有用于供下颌牙齿插入的下齿槽，上咬合套和下咬合套间通过插接件可拆卸连接。该矫治器通过形成患者上颌齿列和下颌齿列的模型，然后使用3D打印机采用液体硅胶增材制造，实现根据患者的牙齿进行矫治器的定制，使得该矫治器更易佩戴，矫治效果更好，同时，通过3D打印，缩短了该矫治器的制造周期，降低了制造难度。

一种负载DMOG和rhBMP-2的3D打印Mg-CHA骨修复材料及其制备方法

Resumen de: CN119548668A

本发明提供一种负载DMOG和rhBMP‑2的3D打印Mg‑CHA骨修复材料及其制备方法，本方法采用镁离子修饰碳酸化羟基磷灰石得到Mg‑CHA，所述Mg‑CHA上吸附有DMOG，且所述Mg‑CHA上的Mg2+与巯基化后的rhBMP‑2配位配合；本发明通过物理吸附使DMOG与Mg‑CHA表面的介孔充分接触，并大量修饰在Mg‑CHA上，rhBMP‑2通过巯基化修饰后，与Mg‑CHA表面的Mg2+金属配位形成化学吸附，由于化学吸附比物理吸附更牢固，可以实现DMOG和rhBMP的顺序释放，从而协同作用促进成骨，具有作为3D打印骨修复材料的巨大潜力。

METHOD AND DEVICE FOR PRODUCING AN IMPLANT

Resumen de: US2021212834A1

The invention relates to a method and a device for producing an implant, wherein a natural bone microstructure of a natural bone region is detected (S1), an implant region in the natural bone region is marked (S2), the detected bone microstructure in the marked implant region is analysed to determine reproduction parameters (S3), and on the basis of the determined reproduction parameters, an artificial microstructure for producing the implant is created (S4).

3D打印准直器内的自含式CT闪烁体

Resumen de: CN119523510A

本公开涉及3D打印准直器内的自含式CT闪烁体。提供了患者后准直器和制造患者后准直器的方法。一种示例方法包括：增材制造具有多个锥形腔的准直器阵列；将多个闪烁体像素定位在该准直器阵列的这些锥形腔内；以及使这些像素在这些锥形腔内硬化。一种示例患者后准直器包括：准直器阵列，该准直器阵列包括多个腔，其中该多个腔中的每个腔包括锥形壁；闪烁体，该闪烁体包括多个像素，该多个像素中的每个像素与该准直器的该多个腔中的一个腔一起定位；和反射器，该反射器定位在该多个像素中的每个像素的顶部上。

一种负载当归多糖的生物支架及在修复全层软骨缺损中的应用

Resumen de: CN119524202A

本发明涉及生物支架技术领域，且公开了一种负载当归多糖的生物支架及在修复全层软骨缺损中的应用，本发明通过3D打印技术构造多孔的聚己内酯支架，并采用聚多巴胺对其进行化学改性，增加了支架的亲水性；同时制备聚(乳酸‑乙醇酸)纳米微球，用来包裹当归多糖，并与PCL/PDA支架结合，形成当归多糖的生物支架用于修复全层软骨缺损。本发明通过借助3D打印技术，能将负载当归多糖的生物支架加工成与需要修复部位的解剖结构外形精确匹配的形态，使其更好地贴合缺损处，为软骨修复提供基础框架，为全层软骨缺损修复材料的发展和技术革新带来了希望。

一种基于磁电技术的电活性伤口敷料体系及其制备方法和应用

Resumen de: CN119523733A

本发明一种基于磁电技术的电活性伤口敷料体系及其制备方法和应用，属于伤口愈合医疗仪器技术领域，本发明提供的基于磁电技术的电活性伤口敷料体系，包括磁电复合电活性伤口敷料、便携医疗背包和移动应用程序。本发明中所述磁电复合电活性伤口敷料生物相容性强，电流输出水平在微安级别，可以满足生物调控的需求，用户通过电子设备上的移动应用程序实现程序化时序调控策略的顺序进行，以无线、迅捷、精准地调节所述磁电复合电活性伤口敷料的电流输出，从而实现了按需电刺激治疗，实现超快速的早期伤口愈合。

カテーテルの場所及び力を感知するシステム及び方法

Resumen de: US2025057440A1

Magnetic field sensors and methods for 3D-printing of the same are disclosed. The magnetic field sensor includes a monolithic body with a plurality of coils 3D-printed therein by successive printing of layers along a printing direction; the coils include longitudinally oriented coil(s) whose magnetic axe(s) are parallel to the printing direction and transversely oriented coil(s) whose magnetic axe(s) are perpendicular to the printing direction. The transversely oriented coil(s) is each 3D-printed with a magnetic channel that curves between a pair of opposite flux collection facets being perpendicular to its magnetic axis, such that it includes a magnetic core section extending along the printing direction. Each of the longitudinally and transversely oriented coils is 3D-printed with respective arrangement of conductive windings including a plurality of turns 3D-printed in planes of the 3D-printed layers. The turns of transversely oriented coil surround the magnetic core section to the magnetic channel thereof.

コイルを含む電気部品及び３Ｄ印刷によって電気部品を製作するための方法

Resumen de: US2025057440A1

Magnetic field sensors and methods for 3D-printing of the same are disclosed. The magnetic field sensor includes a monolithic body with a plurality of coils 3D-printed therein by successive printing of layers along a printing direction; the coils include longitudinally oriented coil(s) whose magnetic axe(s) are parallel to the printing direction and transversely oriented coil(s) whose magnetic axe(s) are perpendicular to the printing direction. The transversely oriented coil(s) is each 3D-printed with a magnetic channel that curves between a pair of opposite flux collection facets being perpendicular to its magnetic axis, such that it includes a magnetic core section extending along the printing direction. Each of the longitudinally and transversely oriented coils is 3D-printed with respective arrangement of conductive windings including a plurality of turns 3D-printed in planes of the 3D-printed layers. The turns of transversely oriented coil surround the magnetic core section to the magnetic channel thereof.

一种包含氧化石墨烯气凝胶和生物胶水的支架及制备方法

Resumen de: CN119524198A

本发明属于生物医药技术领域，涉及一种包含氧化石墨烯气凝胶和生物胶水的支架及制备方法。本发明提供了一种包含氧化石墨烯气凝胶和生物胶水的支架，所述支架包括氧化石墨烯气凝胶和生物胶水；所述氧化石墨烯气凝胶为网格状；所述生物胶水为包含明胶和氧化葡聚糖的混合液体被设置于所述氧化石墨烯气凝胶的内部任意区域，然后明胶和氧化葡聚糖交联成胶。本发明解决了热疗时氧化石墨烯支架光热效能稳定，但难以长时间在局部产生可控的光热作用的技术问题。

一种可定位牙合支托凹的预备导板、相关车针及其制作方法

Nº publicación: CN119523660A 28/02/2025

Solicitante:

中国人民解放军空军军医大学

Resumen de: CN119523660A

本发明公开了一种可定位牙合支托凹的预备导板、相关车针及其制作方法。所公开的预备导板的邻牙覆盖结构上与邻牙待磨除区域对应的部位为开口结构，同时与邻牙待磨除区域对应的开口结构靠近缺牙区覆盖结构，且与邻牙待磨除区域对应的开口结构与邻牙覆盖结构之间形成导平面，该导平面沿义齿就位道方向设置；所述邻牙覆盖结构上与牙合支托凹对应的部位为开口结构，并且与牙合支托凹对应的开口结构的边缘沿邻牙长轴方向延伸形成牙合支托凹定位导轨；同时牙合支托凹定位导轨侧壁开设有车针进入口。本发明将牙合支托凹的预备与预先在数字化模型上设计的牙合支托凹保持一致，并同期完成可摘局部义齿支架的制作。具有临床操作简易，精准度高并减少患者就诊次数的优点。