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Última actualización
03/05/2025 [07:21:00]
Resultados 25 a 50 de 180
Resumen de: AU2023346376A1
The disclosure encompasses systems, compositions, and methods for use in vivo, including for reinforcement of soft tissue in an individual. The systems, compositions, and methods may utilize three-dimensionally printed scaffolds comprising at least a polymer scaffold and an extracellular matrix component(s), including comprised on the scaffold. The polymer scaffold may comprise particular unit cell structures of a specific design and patterns of alternating configurations of the unit cell structures.
Resumen de: WO2025090024A1
A printable shape memory polymer composition for use in fabricating a 4D printed dental aligner is provided The composition comprises a first (meth)acrylate monomer, a second (meth)acrylate monomer which provides transient crosslinks to the printable shape memory polymer composition, one or more crosslinkers, and a photoinitiator, wherein the printable shape memory polymer composition is responsive to change in temperature at temperature Tg to become flexible, allowing the printable shape memory polymer composition to be shaped and reshaped at temperature Tg. A 4D printed dental aligner comprising the printable shape memory polymer composition is also disclosed.
Resumen de: WO2025090537A1
The present disclosure provides systems and methods for fabricating an orthodontic retainer comprising a retainer base. The methods may include obtaining a first digital model representing the palate and the upper teeth of a patient. The methods may include creating, based on the first digital model, a second digital model representing the retainer base and a third digital model representing a teeth shell, and creating, based on the second digital model and the third digital model, a fourth digital model representing the retainer base and the teeth shell that are connected via a connecting structure. The methods may include generating a printed assembly by printing the fourth digital model using a first curable resin material. The printed assembly may at least include the retainer base, the teeth shell, and the connecting structure. The methods may include post-processing the printed assembly to obtain the retainer base.
Resumen de: EP4545060A1
A three-dimensional printing composition includes: a polymerizable monomer; inorganic particles; and a photopolymerization initiator. The inorganic particles are surface-treated with a compound represented by a general formula (1)(in the general formula, R1 is a hydrogen atom or a methyl group; R2 is a hydrolyzable group; R3 is a hydrocarbon group having 1 or more and 6 or less carbon atoms; p is 2 or 3; and q is an integer of 5 or more and 13 or less).
Resumen de: WO2025022873A1
The present invention addresses the problem of providing a photosensitive resin composition that, when in the form of a cured film, has high transparency and chemical resistance, has low film stress, and has high adhesion to metal layers containing molybdenum, aluminum, or nickel. In order to solve such a problem, the present invention proposes a photosensitive resin composition comprising a metal chelator, a photo-radical polymerization initiator, and a siloxane resin having a radically-polymerizable group, where the content of an organosilane unit (D unit) represented by (R)2SiO2/2 (R is an organic group) in the siloxane resin having a radically-polymerizable group is 30-85 mol% with respect to 100 mol% of all of the organosilane units.
Resumen de: US12285220B1
A system and method for planning and simulating a surgical operation to create a patient-specific spinal implant are disclosed. The system comprises a remote server configured to receive patient-specific medical image data and generate a 3D mesh model of the patient's spine using algorithms that separate vertebral bodies, remove artifacts, and smooth surfaces. A doctor's computer receives the 3D mesh model and allows real-time manipulation of intervertebral spaces to achieve a desired spinal curvature. The server generates a spinal implant design with surface-mapped endplates matching the patient's vertebral anatomy, which is transmitted to a 3D printer for manufacturing. The method includes steps of receiving image data, generating and updating the 3D mesh model based on doctor input, generating the final implant design, and transmitting it for production. The invention enables the creation of patient-specific spinal implants with improved conformity and surgical outcomes.
Resumen de: CN119896501A
本发明涉及一种3D打印个体化HTO术中快拆撑开器，属于HTO截骨技术领域，包括多个采取锁扣结构进行组合形成楔形垫块的分块和用于对多个分块进行锁定的锁销。本发明通过多个分块的组合结构使垫块是可拆分的，便于手术完成后轻松取出，并不需要破坏才能取出，从而避免内部未消毒碎片的污染风险，并通过锁扣结构进行组合、锁销进行锁定，形成整体的楔形垫块，从而保证下肢力线的准确矫正，安全性和便携性得到显著提升。
Resumen de: CN119896547A
本发明涉及外科器械材料领域，更具体的是涉及一种透明3D打印手术导向器及材料。导向器包括基体，基体由透明3D打印材料制成，用于附着在目标骨骼的外表面；基体包含多个解剖附着部，每个解剖附着部的附着面分别对应不同解剖部位；多个传感器，用于实时监测解剖附着部与目标骨骼的贴合情况；信号转换模块，嵌入在基体内部，用于将传感器的信号转换为可视信号；多个微型灯泡，微型灯泡镶嵌在基体内部，微型灯泡与信号转换模块连接，微型灯泡的亮度根据传感器的信号变化而变化；电源模块，用于为传感器、信号转换模块和微型灯泡提供电力。本发明提供了一种兼具全域可视化、解剖普适性和实时力反馈的新型手术导向器。
Resumen de: KR20220049473A
The present invention relates to a method for designing dental restorations. The method comprises: determining a target data set on the basis of natural teeth to reflect at least one of optical characteristics and geometry of the natural teeth (S101); creating a digital teeth model having an internal architecture (S102); rendering the digital teeth model on the basis of the internal architecture to create an actual data set reflecting at least one of the optical characteristics and geometry of the digital teeth model (S103); calculating a deviation between the target data set and the actual data set (S104); and iteratively changing the digital teeth model to obtain a small deviation between the detected target data set and an actual data set of a re-rendered digital tooth model (S105).
Resumen de: US2022389373A1
One aspect of the invention provides a method of generating three-dimensional biological structures. The method includes: (a) depositing a first layer of a suspension over a substrate, the suspension including a liquid and a plurality of cells; (b) allowing the plurality of cells to attach to the substrate and form a first layer of attached cells; (c) depositing a cell-attachment agent over the first layer of attached cells; and (d) depositing a second layer of the suspension over the cell-attachment agent.
Resumen de: US2024217166A1
A bio-ink for use in 3D printing, the related conjugate and the preparation process of an intermediate consisting of a bifunctional photoreactive linker are described. Said bio-inks are used for the manufacturing of constructs by 3D printing.
Resumen de: CN119868647A
本发明属于医用支架技术领域，特别涉及一种具有多层次孔结构的聚己内酯支架及其制备方法和应用。本发明聚己内酯支架包括聚己内酯支架本体，以及附着在聚己内酯支架本体表面的ZIF8；聚己内酯支架本体的基体材料为聚己内酯，聚己内酯的纤维之间及纤维表面均具有微米孔结构，纤维之间的微米孔结构的尺寸大于纤维表面的微米孔结构的尺寸。本发明聚己内酯支架本体具有宏观大孔及微观小孔，可提高支架本体的比表面积，表面粗糙度，进而提高聚己内酯支架本体的降解效果，还可促进细胞粘附；此外，大比表面积可为ZIF8沉积提供更多的位点，利于提升聚己内酯支架的生物活性，适于骨缺损的再生修复，且具有良好的机械强度、生物相容性、抗菌性。
Resumen de: FR3154339A1
La présente invention a pour objet un procédé d’irradiation sélective contrôlée d’une zone cible d’une surface d’un produit ou d’un être vivant donné, pour permettre la radiation locale de cette zone cible en vue d’obtenir un effet cible, ce procédé étant mis en œuvre par un système comprenant un dispositif émetteur, au moins un dispositif de mesure et d’analyse et un dispositif contrôleur, ce procédé comprenant des étapes de :-mesure et enregistrement en temps réel de l’énergie principale réelle au niveau de la zone cible,-analyse et enregistrement de l’effet réel obtenu au niveau de cette zone cible, et-contrôle en temps réel du dispositif émetteur par le dispositif contrôleur, en prenant en compte la mesure de l’énergie principale réelle et l’analyse de l’effet réel, lesquelles sont comparées respectivement à un seuil énergétique prédéterminé associé à la zone cible et à l’effet cible attendu, de manière à ce que, si le seuil énergétique prédéterminé n’est pas atteint mais l’effet cible est obtenu, l’irradiation de la zone cible est stoppée. Figure pour l'abrégé : 1
Resumen de: CN119867768A
本发明公开了一种可定制的微丝电极阵列及其制备方法，该可定制的微丝电极阵列包括可定制基底，所述可定制基底内部设有根据脑区定制化分布的穿孔槽；微丝电极阵列，所述微丝电极阵列从上向下穿过所述穿孔槽；封装材料，所述封装材料位于可定制基底底部，用于固定微丝电极阵列。该微丝电极阵列具有较好的灵活性，加工较为简单。
Resumen de: WO2024011290A1
A patient interface comprising a plenum chamber, a seal-forming structure constructed and arranged to form a seal with a region of the patient's face surrounding an entrance to the patient's airways, and a vent to allow a continuous flow of gases exhaled by the patient from an interior of the plenum chamber to ambient. The seal-forming structure may comprise a cushion, the cushion being deformable and resilient and at least partially formed by a lattice structure.
Resumen de: CN119875333A
本发明提供了一种白磷钙石‑聚乙二醇‑聚乳酸形状记忆聚合物及其制备方法以及在制备骨修复支架中的应用，属于生物医用材料技术领域。本发明采用聚乙二醇和白磷钙石分别作为构建电生理微环境促进成骨和调节聚合物变形温度的改性材料，与聚乳酸基体进行物理共混，制备出3D打印形状记忆聚乳酸基复合材料。根据人体股骨受力情况，设计应力诱导结构骨支架，符合人体股骨生物力线分布和交错结构特征。本发明通过3D打印技术制备应力诱导结构骨修复支架，其性能兼具玻璃化转变温度较低、电活性较好、形状记忆功能强、生物相容性与可降解性较好，为骨修复支架提供了一种新选择。
Resumen de: CN119867979A
本发明公开了一种全数字化活动支架义齿装置及其制作方法，其包括金属支架，还包括基托和固定在基托上的义齿，所述金属支架上设置有定位凸起，所述基托上设置有与定位凸起配合的定位凹槽，所述金属支架和基托通过粘接方式连接成一体。本发明取消了传统活动支架义齿装置制作工艺中的基托的注塑成型工艺流程，基托和金属支架之间通过定位凸起和定位凹槽相配合来确定组合位置，并通过粘接方式固定成一体，使得活动支架义齿装置的制作时间大大缩短，生产效率能得到很大提升。
Resumen de: CN119868827A
本发明公开了一种可定制核素水凝胶敷贴器的制备方法，包括：采集病灶部位的图像；根据图像进行对病灶进行三维建模；对病灶的三维模型进行切片，并利用3D打印机打印出与病灶部位形状适配的模具；将核素溶液和水凝胶前驱体溶液加入模具，经光照固化，取出水凝胶敷贴器并封装于两层透明胶带间。本申请可针对不同形状病灶定制与病灶部位适配的核素水凝胶敷贴器，有助于提高治疗效果。而且与目前临床主要依靠医护人员描摹病灶形状来制备敷贴器的繁琐过程相比，本申请制备方法更安全、更高效且形状适配度更高。
Resumen de: AU2023315783A1
An advanced manufactured interpenetrating polymer network (AM-IPN) comprising: a primary polymer network; a secondary polymer network, wherein the secondary polymer network is bonded to the primary polymer network via one or more crosslinks, wherein one or more of the primary polymer network, the secondary polymer network and the one or more crosslinks are printed using a synthetic bioink is disclosed. Methods of making and using are also disclosed.
Resumen de: CN119867900A
本发明公开了一种基于3D打印的个性化跗跖关节固定板，其中，包括：第一贴合板、第二贴合板和第三贴合板首尾依次连接组成三角形结构；第一贴合板和第三贴合板的连接处向外凸出设有第一固定部；第一贴合板和第二贴合板的连接处向外凸出设有第二固定部；第二贴合板和第三贴合板的连接处向外凸出设有第三固定部；第一贴合板和第三贴合板整体呈弧形设置，第二贴合板呈直线形设置。本申请采用第一贴合板、第二贴合板、第三贴合板、第一固定部、第二固定部和第三固定部一体成型，实现固定板对内侧楔骨、中间楔骨以及第二跖骨的固定与支撑，实现对近跗跖关节损伤的治疗，既避免了空心螺钉植入难度过高的问题，还能缩短手术时间，降低手术风险和成本。
Resumen de: US2024016578A1
Disclosed herein are methods for manufacturing medical devices, such as implants, joint replacements, graft materials, augmentation materials, prosthetic materials, etc., from solid material reinforced curable resins. Methods of repositioning a patient's teeth using such medical devices are also provided.
Resumen de: WO2025082761A1
The invention provides poly(hydroxy oxazolidone) compounds (PHOx) corresponding to following formula (I) or formula (II): wherein R1, R2,, independently of one another each denote a C1 to C20 alkyl group, preferably a C1 to C10 alkyl group, more preferably a C1 to C3 alkyl group, most preferably a methyl group, and - R3, R4 independently of one another each denote hydrogen or a C1 to C20 alkyl group, preferably a C1 to C10 alkyl group, more preferably a C1 to C3 alkyl group, most preferably a methyl group, and - R5, R5', R6, R6' independently of one another each denote hydrogen or a C1 to C20 alkyl group, preferably a C1 to C10 alkyl group, more preferably a C1 to C3 alkyl group, most preferably a methyl group, or an aryl group, preferably a phenyl group, and - A is an organic linking group selected from a linear, branched, saturated, unsaturated, cyclic and/or non-cyclic aliphatic, aromatic or araliphatic hydrocarbon group, preferably having 1 to 20, more preferably 1 to 12, most preferably 1 to 8 carbon atoms and optionally further containing one or more functional groups selected from ether, ester, amide, amine, carboxyl, sulfur, halogen and/or urethane, and - Optionally A, R3 and R4 in formula (I) are linked to each other to form a cyclic structure, and - Optionally R5 and R5', and/or R6 and R6' in formula (II) are respectively linked to each other to form a cyclic structure, and - R7 is a polymeric chain selected from a polysiloxane or a polyether, and - n is an integer
Resumen de: US2025128230A1
Provided herein are nanoengineered biomaterial inks used to 3D print a biocompatible, flexible electronic device, for example, a hydrogel constructs a biocompatible, flexible electronic device or 3D printed wearable electronic devices. The biocompatible, flexible electronic device may be a crosslinked gelatin-SH-2D-MoS2 nanoassembly. Also provided are methods for nanoengineering a biomaterial ink and for determining a treatment for a subject in need thereof utilizing the biocompatible, flexible electronic device.
Resumen de: US2025127957A1
Disclosed is an additive manufacturing method for producing a bio-mimetic nanocomposite scaffold using a multi-dimensional printer. The method includes generating a bio-mimetic tool path for a given connective tissue; receiving a bio-mimetic nanocomposite printable material into one or more printing heads of the multi-dimensional printer; and dispensing the bio-mimetic nanocomposite printable material in one or more layers on a printing surface, based on the generated bio-mimetic tool path, for producing the bio-mimetic nanocomposite scaffold.
Nº publicación: WO2025083309A1 24/04/2025
Solicitante:
ADMINISTRACION GENERAL DE LA COMUNIDAD AUTONOMA DE EUSKADI [ES]
ADMINISTRACI\u00D3N GENERAL DE LA COMUNIDAD AUT\u00D3NOMA DE EUSKADI
Resumen de: WO2025083309A1
The present invention relates to a device (1) comprising: a hollow elongated body (2), with a longitudinal central channel (3); a temperature-controlled reservoir (4) intended for storing a fluid to be dispensed; an extruder (5), coupled to the reservoir (4), which exerts pressure on the fluid; a drive shaft (6), coupled to the extruder (5), arranged longitudinally through the central channel (3) of the body (2), and projecting therefrom through the second end; and a head (7) that has a coupling region (10) for coupling to the reservoir (4), a nozzle (8) emerging from the coupling region (10), and an inner channel (9) extending through the coupling region (10) and the nozzle (8), wherein the head (7) may comprise an articulated section (11) that allows orienting the nozzle (8) to achieve greater dispensing precision.
BOPI
Sede Electrónica
