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223
resultados
Última actualización
21/06/2025 [08:30:00]
Resultados 25 a 50 de 223
Resumen de: WO2025124741A1
The instant invention relates to a powder layer for use in 3D binder jetting printing comprising a hydrolyzed and functionalized starch compound. It also relates to a process for 3D binder jetting printing using the same. It also relates to products, in particular solid dosage forms, obtained thereof by 3D binder jetting printing.
Resumen de: US2025195196A1
The development of devices for a functional cure for diabetes by mimicking native pancreatic tissue for production of all pancreatic hormones. A physiologically and mechanically biocompatible artificial pancreas, wherein the pancreas comprises a combination of a PVA hydrogel combined with cells selected from the group consisting of islets; clusters of islets; Beta cells, and combinations of islets and Beta cells. The bioartificial pancreas contains vascular grafts therein or thereon a wall of the pancreas so that said grafts are an integral part of the wall of the bioartificial pancreas. The grafts can be anasmotized to living blood vessels in the body.
Resumen de: US2025195230A1
A computer-implemented method for designing a patient-specific orthopedic implant can include creating a user account associated with a patient. A patient-specific orthopedic implant can be designed based on patient data and imaging data. A healthcare provider can provide feedback for a design of the patient-specific orthopedic implant, treatment protocol, or other aspects of treatment. The patient can provide data and feedback.
Resumen de: US2025195231A1
Systems, devices, and methods are provided for orthopedic implants. The implants may include a base member, such as an acetabular shell or an augment, that is configured to couple with an augment, flange cup, mounting member, or any other suitable orthopedic attachment.
Resumen de: US2025195174A1
Dental appliances for treatment of a patient's dentition are provided. In some embodiments, a dental appliance includes a plurality of 3D printed polymer layers, where the plurality of 3D printed polymer layers includes a plurality of sequentially polymerized appliance cross-sections. The dental appliance can include an appliance shell formed from the plurality of sequentially polymerized appliance cross-sections. The appliance shell can include a plurality of tooth receiving cavities formed from the plurality of sequentially polymerized appliance cross-sections, the plurality of tooth receiving cavities arranged to receive a dentition and to exert one or more forces on the dentition, and a plurality of variable thickness regions formed from the plurality of sequentially polymerized appliance cross-sections. The plurality of variable thickness regions can include a corresponding plurality of different appliance thicknesses, and the plurality of variable thickness regions can be arranged to implement one or more treatment outcomes.
Resumen de: US2025195175A1
The present disclosure provides polymerizable composition that can produce desirable stain resistant polymeric materials, polymer compositions, and/or photo-curable resins. Further provided herein are methods of producing polymerizable compositions, resins, devices, and polymeric materials. Also provided herein are methods of using polymerizable compositions, resins, and polymeric materials for the fabrication (e.g., via 3D printing) of medical devices, such as orthodontic appliances.
Resumen de: US2025197658A1
This disclosure provides stable polymerizable resin compositions comprising one or more antioxidant stabilizers to prevent undesired polymerization and/or oxidation of polymerizable components as well as undesired depletion of photoinitiators in the polymerizable resin composition. Such polymerizable resin compositions can be used to produce polymeric materials with properties suitable for use in various mechanical appliances, such as orthodontic appliances.
Resumen de: US2025195723A1
Embodiments relate to granular hydrogel bioinks with preserved interconnected porosity for extrusion bioprinting and methods of use and making thereof. The granular hydrogel bioinks comprise hydrogel particles and materials/methods to reversibly connect them to each other without compromising void spaces. These materials/methods include but are not limited to nanoparticles, wherein the nanoparticles are absorbed onto the microgels and wherein the nanoparticles are configured to allow for electrostatic bonding of the microgels. These materials/methods can also include reversible functional groups, selected from guest-host groups and/or dynamic covalent bond forming groups.
Resumen de: US2025197659A1
There is provided a bioink for bioprinting a porous three-dimensional hydrogel structure, the bioink comprising an aqueous medium; and granular crosslinkable hydrogel precursor particles suspended in the aqueous medium, wherein the granular crosslinkable hydrogel precursor particles have an average size of from 100 microns to 500 microns, and wherein under suitable crosslinking conditions, the granular crosslinkable hydrogel precursor particles crosslink and adhere to one another, to form the porous three-dimensional hydrogel structure having pore diameters in the range of from 20 microns to 200 microns. There is also provided a method of forming a porous three-dimensional hydrogel structure using the bioink disclosed herein and a porous three-dimensional hydrogel structure obtained from said method.
Resumen de: WO2025127798A1
The present invention relates to a strontium-emitting 3D printing scaffold for promoting bone cartilage regeneration and a method for manufacturing same. The scaffold continuously maintains the emission of a triad of ions including strontium (Sr), silicate (Si), and calcium (Ca) to promote cell migration to a damaged site, and has a hierarchical porous structure, and thus enhances tissue regeneration by increasing cell engraftment, immune regulation, and angiogenesis, and exhibits an excellent anti-inflammatory effect. Therefore, the scaffold can be effectively used for the regeneration of damaged bone and cartilage tissue.
Resumen de: WO2024033402A1
The invention relates to a maxillary modeller (2) intended to be worn, in a service position, on a dental arch of a user in order to modify the shape of the palate, the maxillary modeller being one-piece and removable and comprising: - a central palatal portion (22) configured to be in contact with the user's palate when the maxillary modeller is in the service position; and - a first and a second dental portion (24; 26) each comprising at least one, preferably multiple cavities configured to receive teeth of the user when the maxillary modeller is in the service position, the first and second dental portions extending on either side of the central palatal portion, the central palatal portion being configured so as to exert on the palate, in the service position, forces suitable for modifying the shape thereof.
Resumen de: AU2023323651A1
Provided is an implantable tissue scaffold comprising a mixture of a biocompatible organic polymer and chitin, wherein the chitin is embedded in the biocompatible organic polymer. Also provided is a composition for 3D printing, the composition comprising at least one biocompatible organic polymer and chitin that may be partially deacetylated, wherein the chitin is embedded within the biocompatible organic polymer. Further provided is a method of promoting tissue formation, comprising implanting a tissue scaffold comprising a mixture of a biocompatible organic polymer and chitin at a site in need of regenerative bone tissue formation.
Resumen de: US12331272B1
An ultra-high-cell-density multicellular tissue lifting bioprinting device assisted by oblique incident bulk wave and a printing method therefor are provided, and the printing device includes a printing liquid tank, a printing platform, a light source and an oblique incident bulk wave chip; the printing liquid tank contains a printing liquid which is a mixture of cells and a photocurable bioink; the printing platform is arranged horizontally and extends into the printing liquid tank to come into contact with the printing liquid; the printing platform is capable of going up and down; the light source is arranged under the printing liquid tank, and light enters the printing liquid tank; the oblique incident bulk wave chip is a piezoelectric transducer arranged obliquely; the piezoelectric transducer is arranged under the printing liquid tank and tilted relative to the horizontal plane to generate an oblique incident bulk wave acoustic field in the printing liquid.
Resumen de: CN222983250U
本实用新型公开了一种用于耳朵术后形态保持的支撑件，包括：内贴合层，外层桁架，所述外层桁架呈罩体形状，所述外层桁架的一侧边缘与所述内贴合层连接；支撑单元，所述支撑单元的数量为多个，所述支撑单元为弹性部件，所述支撑单元设置在所述内贴合层和所述外层桁架之间，所述支撑单元的一端与所述内贴合层连接，所述外层桁架的内侧与所述支撑单元的另一端连接，本实用新型可以提升保持器的舒适性以及支撑强度。
Resumen de: CN120154756A
本发明公开了一种用于修复骨缺损的DAT‑海藻酸钠3D多孔支架、制备方法及应用，本发明提供的DAT‑海藻酸钠3D多孔支架展现了良好的生物学性能和成骨诱导能力，在骨缺损修复中的应用潜力巨大。
Resumen de: AT527771A1
Es wird ein Helm (1) zur nicht-invasiven Hirnstimulation mit einem auf eine Kopfaufnahme (2) gerichteten Stimulationseinheit (3) beschrieben. Um eine präzise Bestrahlung eines individuell bestimmbaren Stimulationsbereichs zu ermöglichen und trotzdem dem Probanden eine gewisse Bewegungsfreiheit zu erlauben wird eine durch eine zur Kopfaufnahme (1) hin offene Absaugöffnung (4) vorgeschlagen, die mit einem außerhalb der Kopfaufnahme (2) angeordneten Unterdruckanschluss (6) strömungsverbunden ist.
Resumen de: CN120131256A
本发明公开了组织工程与再生医学技术领域的一种有支撑富弹性和防逆流功能的组织工程泪道，包括由脱细胞气管基质材料构成的泪道管主体，泪道管主体外表面外覆有外螺旋加固层，外螺旋加固层表面包裹有生物羊膜，泪道管主体的中部设有若干特斯拉阀结构，底部设有防逆流瓣膜。本发明采用脱细胞气管、生物羊膜、3D打印聚氨酯为支架构建组织工程泪道，并将特斯拉阀结构和防逆流瓣膜应用到组织工程泪道，从而保持泪管弹性且防止泪液和鼻腔分泌物及气体逆流。
Resumen de: CN120133517A
本申请属于合金材料技术领域，尤其涉及钛合金粉末材料、钛合金及其制备方法、应用。该钛合金粉末材料包括纳米Fe颗粒、纳米TiO2颗粒和Ti颗粒，其中纳米Fe颗粒、纳米TiO2颗粒分布在Ti颗粒的表面。该钛合金粉末材料中的Fe和TiO2以纳米颗粒的形式存在，并分布在Ti颗粒的表面，这样的分布有利于提高Fe元素和O元素的分布均匀性，缓解元素偏析形成有害力学性能的β‑fleck问题，进而改善钛合金的力学性能均匀性。
Resumen de: CN120132062A
本发明属于生物医学工程与增材制造交叉领域，具体涉及一种3D打印超材料压电型骨缺损修复支架，所述支架的孔隙结构由数学表达式定义的Gyroid、SchwarzP和Diamond三种极小曲面单元复合构成；所述支架的孔隙率为30％‑70％，孔径范围为0.1‑1mm；所述支架的材料为由聚偏氟乙烯、聚乳酸及钛酸钡组成的压电复合材料，所述压电复合材料按质量百分比如下：聚偏氟乙烯(PVDF)30％‑55％，聚乳酸(PLA)20％‑45％，钛酸钡(BaTiO3)10％‑25％，且各组分的质量百分比之和为100％。该发明通过多材料3D打印技术实现宏观结构及微观结构的精准调控，具有力学适配性、降解可控性和主动促进骨再生功能，适用于颅颌面、四肢长骨等大段骨缺损修复场景。
Resumen de: CN120133543A
本发明涉及一种基于极小曲面结构的多孔钽材料的制备方法及其医疗应用，尤其应用于椎间融合器、人工椎体、髋关节臼杯、关节填充块和牙种植体等医疗植入物。材料为纯钽或含钽合金（如钽钛、钽铌、钽锆、钽钛铌锆，钽含量大于1%），采用增材制造技术构建，孔隙率30~90%，其相比于桁架孔道结构（如菱形十二面体）无明显的应力集中点，在强度、模量、抗疲劳性能等方面均有显著提升，特别适合用于大面积和承重骨缺损的结构和功能重建。
Resumen de: CN120131133A
本发明提供一种骨性Ⅱ类错颌畸形正颌手术辅助器械组件及其制备方法，截骨辅助部件包括固定支持夹板与第一定位导板，第一定位导板中设有截骨定位槽、钛钉定位孔与髁突位置指示孔，固定支持夹板与第一定位导板通过第一连接杆保持固定姿态连接；定位辅助部件包括咬合夹板、髁突定位板与第二定位导板，髁突定位板贴合于患者的近心段下颌支表面，与患者的下颌支固定连接，第二定位导板中设有钛板定位框，咬合夹板分别与髁突定位板及第二定位导板通过第二连接杆及第三连接杆保持固定姿态连接。通过本发明，可建立与患者颌骨精准适配的截骨辅助部件与定位辅助部件，实现对颌骨的定位与固定功能。
Resumen de: CN120132042A
本发明公开了一种兼具抗菌与促成骨性能的钛基植入物及其制备方法和应用，属于生物医用材料与生物医学交叉技术领域。本发明以选区激光熔化多孔钛合金为基体，利用微弧氧化和水热处理，在其表面构建兼顾抗菌及促成骨的多功能复合涂层；并通过掺杂功能性元素对涂层的微观结构及生物学性能进行调控，从而对涂层的抗菌性能和促成骨性能进行优化。
Resumen de: CN119278190A
The invention relates to a chemical combination for producing a ceramic dispersion or a ceramic gel, to a method for producing a ceramic molded part, and to a ceramic molded part produced by the method.
Resumen de: WO2025120283A1
The invention relates to a method for manufacturing a removable partial dental prosthesis, the method comprising the steps of: a) manufacturing at least one monolithic block comprising an artificial tooth part and an artificial gum part, the monolithic block comprising at least one first joining member; b) manufacturing a frame that is configured to support the monolithic block, the frame comprising at least one second joining member; then c) joining the monolithic block to the frame by interlocking the first joining member with the second joining member to form the removable partial dental prosthesis.
Nº publicación: WO2025120669A1 12/06/2025
Solicitante:
PANDORUM TECH PRIVATE LIMITED [IN]
PANDORUM TECHNOLOGIES PRIVATE LIMITED
Resumen de: WO2025120669A1
The present disclosure provides a three-dimensional hydrogel prepared using a bioink composition comprising methacrylated hyaluronic acid, methacrylated gelatin, a photoinitiator and a photoabsorber; and a method for preparing the three- dimensional hydrogel or lenticule. The present disclosure further provides a method of treating corneal tissue repair in a subject in need thereof using the three- dimensional hydrogel or lenticule.
BOPI
Sede Electrónica
