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Techniques for generating superresolution presentations of medical procedure video data

Resumen de: US12745894B1

0000 In some embodiments, a method of automatically generating high-resolution images of features of interest to accompany video data of a medical procedure of a given type is provided. A computing system provides the video data of the medical procedure to a first machine learning model trained to annotate features of interest. The computing system provides annotated portions of the video data to a second machine learning model trained on past images of features of interest to produce superresolution images of features of interest. The computing system generates a presentation of the video data of the medical procedure that includes the superresolution images of the features of interest produced by the second machine learning model.

室性心动过速出口位置标识的方法及装置

Resumen de: EP4813296A1

0001 To non-invasively identify a ventricular tachycardia exit site in a heart of a particular patient (107) using electrocardiogram signals and medical imagery for the particular patient, a control circuit (101) can be configured to access (205) a neural network (104) that has been trained (202) using a plurality of synthetic data examples (203) and to input information regarding the electrocardiogram signals and the aforementioned medical imagery for the particular patient to the neural network. The control circuit can then output from the neural network information that identifies a predicted ventricular tachycardia exit site in the heart of the particular patient.

面部光谱与动作单元融合的疼痛评估及视听优选干预系统

Resumen de: CN122842915A

0001 本发明公开了一种面部光谱与动作单元融合的疼痛评估及视听优选干预系统。系统包括：多模态光电感知模块，由高光谱成像单元与RGB成像单元构成，用于同步采集患者面部的高光谱图像和RGB视频图像；特征提取模块，提取面部动作单元强度特征和感兴趣区域的血氧代谢特征；客观疼痛指数构建模块，融合构建客观疼痛指数OPI；视听干预模块，在预设的测试阶段依次播放多种候选镇痛内容，基于OPI实时反馈筛选出个性化最优内容用于后续疼痛期；边缘计算与隐私保护模块，采用个性化联邦学习框架确保原始数据不离开本地。本发明实现了疼痛的连续、客观、非接触式定量评估，并通过内容优选机制提供个性化无创镇痛干预，可应用于产妇分娩镇痛等多种场景。

使用可变温度控制的树脂的增材制造

Resumen de: EP4005777A1

0001 Provided herein are systems and processes to control multiple temperatures in additive manufacturing. Such temperature control adjusts polymer properties and facilitates processing of materials to form 3D objects. The systems and processed disclosed herein also facilitate the processing of typically difficult-to-process materials and deliver such materials to a photocuring zone configured to photopolymerize materials into 3 dimensional objects with a layer-by-layer process. Such processes can include the steps of heating a resin to a flowable temperature, applying the resin to a carrier, cooling the film to increase viscosity or to solidify the resin, and applying the film containing the resin onto an area being printed, then photocuring the film. Also provided herein are resins and related polymer materials having properties that are tunable with exposure to more than one temperature zone. The formed polymers can include multiple regions of polymer material, each independently having distinct properties. Processes and systems are also provided herein that are configured to produce polymeric materials having multiple regions with distinct properties from a single-component formulation.

分析物测量的远程监测

Resumen de: JP2018171485A

PROBLEM TO BE SOLVED: To provide methods and apparatuses, including computer program products, for remote monitoring.SOLUTION: A method is provided in some example implementations. The method may include: receiving, at a remote monitor, a notification message representing an event detected by a server, from analyte sensor data obtained from a receiver monitoring an analyte state of a host; presenting, at the remote monitor, the notification message to activate the remote monitor, the remote monitor being configured by the server to receive the notification message to augment the receiver monitoring the analyte state of the host; accessing, by the remote monitor, the server in response to the presenting of the notification message; and receiving, in response to the accessing, information including at least the analyte sensor data. Related systems, methods, and articles of manufacture are also disclosed.SELECTED DRAWING: Figure 1

用于个性化患者治疗的方案引擎

Resumen de: WO2025147641A1

A system and method for intelligently controlling an individualized infusion is described. A machine learning model is trained to simulate progression of a plurality of conditions across a patient population under a care of a plurality of physicians, and to determine how the progression of each condition is affected by respective medication decisions made by one or more physicians regarding (i) dosing of one or more medications and (ii) a respective pharmacokinetic model of the one or more medications. A condition to be treated is selected for a patient and the system monitors patient biomarkers and determines, in real time, a dose of a medication to administer to the patient to maintain at least one of the biomarkers in a predetermined effective range. The system causes an infusion pump to administer the dose of the medication to the patient and adjusts the dose continuously based on reevaluation of the biomarkers.

최소 침습 및 내시경적 생체내 바이오프린팅 시스템 및 방법

Resumen de: WO2025163396A2

A system may include a donor supply sub-system configured to supply donor material to a donor substrate. The system may include a material transfer sub-system comprising a laser configured to illuminate the donor substrate via a transfer beam. The system may include an instrument head of a medical instrument configured to house the donor substrate, wherein upon an illumination of the donor substrate, the donor material is transferred to receiver material in vivo.

用于识别和监测医疗程序中的无菌状态的计算机视觉架构

Resumen de: WO2025184384A1

Aspects of this technical solution can include identifying, using a first model configured to detect image features, an object within an image of a medical environment, classifying, using a second model, the object to associate a sterility status with the object, the sterility status indicative of a first state of the object as sterile or a second state of the object as non-sterile, monitoring, using the first model, movement of the object within the medical environment, determining, based on the movement of the object within the medical environment, a metric indicative of a risk of breach of sterility of the object, and generating, in response to the metric meeting a threshold indicative of the second state of the object as non-sterile, an output in real¬ time indicative of the metric meeting the threshold.

基于药物敏感性确定和自定义药物递送的方法和系统

Resumen de: WO2025188456A1

Disclosed is a method of determining sensitivity by a patient to a medication delivered at a delivery frequency including perturbing the delivery amount by a perturbation amount at a perturbation frequency, defining a perturbation signal, measuring a patient response to the perturbation, and recovering the effect of the perturbation. Also disclosed is a system for determining sensitivity by a patient to a medication including a processor configured for the method.

動態画像解析装置、方法、及びプログラム

Resumen de: US20250366810A1

0000 A dynamic image analysis apparatus includes an acquisition unit that acquires a dynamic image of an imaging target by dynamic imaging; and a calculation unit that calculates, from the dynamic image, two pieces of displacement amount data related to a region obtained by dividing a still image constituting the dynamic image and change amount data related to a density of the region.

ULTRASOUND IMAGING CATHETER GUIDED PULSE FIELD ABLATION

Resumen de: EP4809934A1

Pulse field ablation (PFA) guidance is generated from intracardiac echocardiogram (ICE) imaging. The relative position of the PFA device (450) and the tissue is determined. The treatment placement with respect to the tissue for repetitive application is detected. By finding the relative position and/or treatment placement over time, ICE imaging in combination with image processing may provide visual guidance rather than just imaging or just catheter tracking for PFA. The resulting PFA procedure may be more likely complete and/or optimized.

一种基于心率和呼吸的心理压力分析方法及系统

Resumen de: CN122805272A

0001 本发明提出一种基于心率和呼吸的心理压力分析方法及系统，涉及精神医疗技术领域。该方法通过实时采集用户呼吸信号与心率信号，提取呼吸周期数据及心率变异性数据并进行同步关联分析，揭示自主神经系统与呼吸节律的相互作用。系统将心率变异性数据映射为虚拟现实环境中的颜色控制参数，呼吸周期数据映射为运动控制参数，形成多感官生物反馈。在双用户模式下，通过监测呼吸相位差及动作轨迹重合度触发光域融合效果，实现颜色混合与运动轨迹协同，并结合触发次数动态调整训练关卡难度。本发明解决了单一信号割裂、缺乏社交互动及动态适配能力不足的问题，提升乳腺癌患者康复训练的沉浸感、依从性及个性化适配能力。

パーキンソン病の事例の分類

Resumen de: WO2025057081A1

A system (28) includes multiple electrodes (22) configured to record respective signals produced, by a brain of a patient (12) suffering from a particular subtype of Parkinson's Disease (PD), in response to magnetic stimulation of the brain. The system further includes a processor (32) configured to receive the signals, to identify a subset, of multiple subtypes of PD, to which the particular subtype belongs, by processing the signals, and to output an output indicating the subset of the subtypes. Other embodiments are also described.

一种用于上颌内置式牵引器植入的手术规划、导板设计及机器人系统

Resumen de: CN122805370A

本发明涉及一种用于上颌内置式牵引器植入的手术规划、导板设计及机器人系统，包括：数据采集模块，用于获取患者颅颌面的多模态影像数据，并构建包含硬组织、软组织及空间姿态的数字孪生三维头模；虚拟规划模块，用于在所述数字孪生三维头模的基础上生成患者的个性化手术方案；导板设计模块，用于根据所述个性化手术方案，设计并制造适配于患者的个性化手术导板；以及手术机器人执行模块，其通过光学导航系统验证导板的实际位姿与规划位姿之间的偏差，当偏差小于预设阈值时锁定所述手术导板，并依据所述个性化手术方案和所述个性化手术导板完成截骨、钻孔及牵引器植入操作。

一种基于混合现实的ADHD支持者情感疗愈方法及系统

Resumen de: CN122822233A

0001 本申请涉及计算机技术领域，公开了一种基于混合现实的ADHD支持者情感疗愈方法及系统，旨在解决现有管理导向干预难以在支持者日常空间中建立情感锚点，无法实质性缓解情感耗竭的问题。该方法包括：部署实体装置并叠加虚拟元素，构建物理锚定与数字引导的治疗空间；引导支持者通过音频指令在混合现实环境中建立安全感并激活情感；进入叙事探索阶段，触发中心虚拟对象分解为匿名叙事单元供聆听；播放将情感转化为动态视觉隐喻的视听组合，并融入群体韧性语音进行价值引导；执行程序化收束并提供反思手册。本申请通过实体装置提供触觉安全的物理锚定，融合数字引导完成情感外化与价值重建，有效缓解支持者情感耗竭与孤立感。

Internally Coloured Nano Ceramic Ink for High-Performance Dental Inkjet 3D Printing and Preparation Method Thereof

Resumen de: LU605609B1

The application relates to an internally coloured nano ceramic ink for high- performance dental inkjet 3D printing and a preparation method thereof. The ink of the application has simple components, realizes stable and uniform colouration by adding organometallic salt, and simultaneously introduces an alumina stabilizer and silicate glass powder, so that the dental zirconia ceramic prepared by inkjet 3D printing has an aesthetic effect on the basis of improving the mechanical properties and thermal expansion matching of the ceramic.

医薬剤形及びその製造方法

Resumen de: WO2025055893A1

Provided herein are a pharmaceutical dosage form and a method for preparing thereof, such as a pharmaceutical dosage form prepared by a three-dimensional printing method. Pharmaceutical dosage forms loaded with liquid or semi-solid materials, and pharmaceutical dosage forms loaded with solid material are both provided.

睡眠改善电刺激方法、系统和计算机程序产品

Resumen de: CN122805942A

本专利涉及生物医学工程技术领域，具体涉及一种睡眠改善电刺激方法、系统和计算机程序产品。方法包括：生成用于电刺激的至少两路中频载波信号；施加电刺激，并通过电极同步采集叠加有所述中频载波信号的脑电图信号；使所述脑电图信号通过一混合模拟滤波网络，以在模拟域对叠加的所述中频载波信号进行物理衰减；对所述脑电图信号进行模数转换；基于经过所述物理衰减和模数转换后的信号，识别当前睡眠所在时期；根据所述睡眠时期的识别结果，调控所述电刺激参数。通过在模数转换之前于模拟域对干扰信号实施物理衰减，从根源上解决了强载波干扰导致后级模数转换器饱和的物理瓶颈，确保了微弱脑电信号能够被高保真地同步采集。

酵素およびナノザイムを内包する微粒子

Resumen de: WO2025043269A1

This invention describes microcapsule compositions and methods to encapsulate gas modulating enzymes or nanozymes at unprecedented concentrations and stability, that can be used to regulate the local gas concentrations. Microcapsules can be comprised of gelatin with a polydopamine coating. This system can replace expensive incubators/chambers and is the first system that can create spatiotemporal gradients of gases within a finite volume. The microcapsules have a broad range of applications in tissue culture, bioprinting, in vivo, and industrial uses.

MEW TISSUE SCAFFOLD

Resumen de: US2022257371A1

0001 The disclosure relates to a melt electrowritten soft tissue scaffold and methods of making the same. The scaffold has a body having a first region comprising a first set of fibres and a second set of fibres, the first region being anisotropic. The first set of fibres are arranged approximately parallel relative to one another, each fibre of the first set of fibres has a serpentine arrangement forming peaks and troughs, the first set of fibres has a first Young's modulus. The second set of fibres are arranged approximately parallel relative to one another, the second set of fibres being arranged transversely relative to the first set of fibres, each fibre of the second set of fibres has a serpentine arrangement forming peaks and troughs, the second set of fibres has a second Young's modulus. The first Young's modulus is unequal to the second Young's modulus. In some embodiments the body further comprises a second region extending from the first region. The second region supports the first region.

メタクリル化ｄＥＣＭの製造方法

Resumen de: AU2024328750A1

Process for methacrylation of dECM comprising placing a carbonate buffer with a concentration of 1M in the reaction vessel and heating to a temperature of 50 °C, adding dECM to the carbonate buffer to obtain a dECM solution with a concentration of 4% (w/v), sterilizing this solution by irradiation with radiation UV for 15 minutes, adding methacrylic anhydride in an amount of 0.5 mL/1g dECM and reacting at 50 °C for 1 h, then adding a phosphate-buffered saline solution to obtain a 5-fold dilution of the mixture, placing the obtained solution in dialysis tube, and then placing the dialysis tube in deionized water, this stage is carried out at a temperature of 40 °C for no longer than 4 days, after completing this stage, the solution contained in the dialysis tubes is transferred to aluminum trays and then placed at a temperature -80 °C for at least 3 hours, then the frozen solution is freeze-dried under the following conditions: shelf temperature 10 °C, pressure 0.1 mba, freeze-drying time 48 hours. The invention also relates to methacrylated dECM obtained by the above method and to the use of methacrylated dECM obtained by the above method in the bioprinting process.

利用低采样率加速度计数据的生理监测

Resumen de: US20260096746A1

0000 Techniques for physiological monitoring using low sample rate accelerometer data are described and are implementable to generate insights related to user states during extended wear periods. In an example, low sample rate accelerometer data having a sample rate that is below a sample rate threshold is received from a wearable device mounted on a skin surface of a chest region of a user during a wear period. The low sample rate accelerometer data is processed to extract one or more motion-derived parameters that characterize temporal movement patterns of the user during the wear period. An insight for presentation related to a user state during the wear period is generated based on the one or more motion-derived parameters. The insights can include but are not limited to predictions of sleep states, active states, and inactive states, body angle and position determinations, and detection of device inversion events.

基于扩散概率模型的颌骨缺损虚拟重建与修复体建模方法及系统

Resumen de: CN122820921A

本发明属于医学图像处理设计领域，具体涉及了基于扩散概率模型的颌骨缺损虚拟重建与修复体建模方法及系统，包括根据颌骨解剖与力学数据构建多通道条件张量；以颌骨密度场和修复体有向距离场形成联合状态，建立骨密度退变与修复体松动耦合的前向退变随机微分方程；训练基于分数网络的条件对数梯度估计器，计算物理一致性损失与神经管避让损失；求解逆向愈合随机微分方程，获得重建颌骨密度场和修复体有向距离场；提取表面网格输出模型。本发明能在统一扩散概率框架下协同生成颌骨修复模型和修复体模型，兼顾形态、力学及神经管约束。

空间分割放疗的晶格点阵生成方法、装置、设备及介质

Resumen de: CN122826594A

本公开提供了一种空间分割放疗的晶格点阵生成方法、装置、设备及介质，该方法包括基于目标对象的医学影像，确定肿瘤靶区以及位于肿瘤靶区内的生物异质区；确定对应于肿瘤靶区内的基础区域的第一晶格参数集以及对应于生物异质区的第二晶格参数集，基础区域为在肿瘤靶区内除去生物异质区之外的区域，第二晶格参数集中至少存在一个参数数值与第一晶格参数集中对应的参数数值是不同的，以增大所述生物异质区内的晶格体积占比；根据第一晶格参数集在基础区域内生成第一晶格点阵；根据第二晶格参数集在生物异质区内生成第二晶格点阵。

机器人系统力数据配置以兼容网络传输

Nº publicación: CN122826829A 25/09/2026

Solicitante:

直观外科手术操作公司

Resumen de: WO2025184382A1

Configuration of force data of robotic systems for compatibility with network transmissions is provided. A system receives a data set corresponding to force at an instrument of a robotic medical system during a medical procedure. The system removes first points from the data set that satisfy a first threshold indicative of a first magnitude of force at the instrument of the robotic system. The system identifies, with a machine learning model and from the data set with the one or more first points removed, one or more second points that satisfy a second threshold indicative of a second magnitude of force at instrument of the robotic medical system. The system causes a user interface to present one or more videos for one or more times during the medical procedure that correspond to the one or more second points from the data set.