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ORTHODONTIC DEVICE AND METHOD

Resumen de: WO2026150214A1

A dental appliance for correcting jaw relationships in a patient having a mandible comprising lower teeth and a maxilla comprising upper teeth, said dental appliance comprising: a lower shell for fitting over the lower teeth; and an upper shell for fitting over the upper teeth; wherein the lower shell and the upper shell each comprise a mandibular alteration ridge configured to project occlusally on each side of the shell; wherein each mandibular alteration ridge comprises at least one guide block comprising a guide surface and one or more buttresses; wherein the one or more buttresses intersect said guide block at a non-terminal point; wherein the guide block and the one or more buttresses have the same height at the point of intersection; and wherein the guide surface of a mandibular alteration ridge of the upper shell is configured to engage the guide surface of a mandibular alteration ridge of the lower shell to displace the mandible relative to the maxilla as the jaw closes is provided. A method of correcting a Class II or Class III malocclusion is also provided.

Modellaufnahmekörper zur Befestigung eines Kiefermodells

Resumen de: DE102025107060B3

Modellaufnahmekörper (1) zur Befestigung eines Kiefermodells (2) in einem Artikulator (3), wobei der Modellaufnahmekörper (1) eine erste Seite (4) zur Befestigung des Kiefermodells (2) und eine zweite, der ersten Seite (4) gegenüberliegende, Seite (5) aufweist, wobei der Modellaufnahmekörper (1) mehrere Auflagestege (6) für das Kiefermodell (2) und eine Befestigungseinrichtung (7) zur magnetischen Befestigung des Modellaufnahmekörpers (1) am Artikulator (3) oder an einer Adapterplatte (8) aufweist, wobei zwischen den Auflagestegen (6) zur ersten Seite hin offene Freiräume (9) in dem Modellaufnahmekörper (1) ausgebildet sind, und die Auflagestege (6) Auflageflächen (10) zur Abstützung des Kiefermodells (2) in einer ersten, von der zweiten Seite (5) weg weisenden Richtung (11) aufweisen, wobei der Modellaufnahmekörper (2) zumindest zwei, vorzugsweise drei, voneinander distanziert angeordnete und in der ersten Richtung (11) über die Auflageflächen (10) überstehende Lagesicherungsstifte (12) zum Ausrichten des Kiefermodells (2) in zwei, zur ersten Richtung (11) und auch zueinander, orthogonalen Richtungen (13, 14) aufweist.

SWEAT SENSOR HAVING DUJIANGYAN-INSPIRED DIVERSION STRUCTURE

Resumen de: WO2026148698A1

The present invention relates to a sweat sensor having a Dujiangyan-inspired diversion structure. The sweat sensor comprises a detection layer and a sealing layer provided on the detection layer; the detection layer is provided with a sample collection hole, a sample flow channel communicated with the sample collection hole and extending to the outside of the detection layer, and a plurality of detection chambers arranged on one side of the sample flow channel; one end of each detection chamber is connected to the sample flow channel by means of a first flow channel, and the other end is connected to the sample flow channel by means of a second flow channel; the sample flow channel, the first flow channel, the detection chamber, and the second flow channel define a diversion dike; a sample enters the sample flow channel from the sample collection hole, and after being diverted by the diversion dikes, a part of the sample flows to the detection chambers along the first flow channels; a plurality of water stop grooves are provided on the side wall of the sample flow channel distant from the diversion dikes; and sample detection chips are arranged in the detection chambers. The sweat sensor designed in the present application exhibits reduced sweat evaporation loss and a more accurate sweat detection result.

SYSTEMS AND METHODS FOR FABRICATING HYDROGELS WITH INTRINSIC VASCULAR CHANNELS FOR LIVER TISSUE ENGINEERING

Resumen de: US20260199559A1

0000 Disclosed are implantable devices, systems, and methods of fabricating, testing, optimizing, and/or implanting such devices. An implantable device includes a body, a first intrinsic channel network formed in the body and configured to receive cells, and a second intrinsic channel network formed in the body and configured to allow for active flow of a fluid to support viability and/or function of the cells in the first intrinsic channel network. The first intrinsic channel network comprises a first channel and the second intrinsic channel network comprises a second channel, with at least segments of the first and second channels parallel to and spaced apart from each other. Cells may be suspended in a collagen matrix and introduced to the first intrinsic channel network.

SYSTEM WITH INBUILT MOBILE CELLULAR COMMUNICATION CAPABILITY AND BODY VITAL MEASURING CAPABILITY WEARABLE ON A HUMAN FINGER

Resumen de: WO2026151455A1

The present invention relates to a wearable communication smart device in the form of ring which provides two way communication system through wireless and cellular networks. The smart device comprises of physical body and a software functionality built for smooth running of the smart device.

MOISTURE CHAMBER ADAPTED FOR USE WITH EYEGLASSES

Resumen de: AU2025286486A1

A moisture chamber adapted for use with eyeglasses. The moisture chamber is a single-use, disposable, component that is temporarily adhered to the inside of a the lens of a pair of glasses. The moisture chamber may be used on one or both of the lenses and works by creating a moist environment for the eye to help alleviate dry eyes. The moisture chamber may be made of silicon and may be 3-D printed.

PROGRAMMABLE PRINTED MESH CONSTRUCTS

Resumen de: WO2026152022A1

A printed mesh construct comprises a polymer material arranged in a mesh with multiple intersections, wherein the polymer material is fused at the multiple intersections to form a single unitary body. A method of manufacturing a printed mesh construct includes printing polymer material to form a plurality of intersections of polymer material, wherein the plurality of intersections of polymer material are fused intersections. Further, a printed mesh construct having polymer material arranged in a mesh having a plurality of intersections, wherein the plurality of intersections comprise fused polymer material, wherein the printed mesh construct has a substantially two-dimensional shape in a first configuration, wherein the printed mesh construct has a substantially three-dimensional shape in a second configuration, and wherein the printed mesh construct is configured to transition from the first configuration to the second configuration upon application of a force to the printed mesh construct.

THREE-DIMENSIONAL PRINTING OF ARTIFICIAL BONE MARROW NICHES USING MESENCHYMAL STEM CELLS ENCAPSULATED IN HYDROGELS

Resumen de: WO2026151656A1

Methods, systems, apparatuses, and computer program products are described herein for printing artificial constructs or tissue models from a bioink using digital light processing (DLP). Bioinks can include polyethylene glycol diacrylate (PEGDA), gelatin methacrylate (GelMA), hyaluronic acid methacrylate (HAMA), lithium phenyl-2,4,6-trimethylbenzoylphosphinate (LAP), tartrazine, arginine-glycerine-aspartic acid (RGD), isoleucine-lysine-valine-alanine-valine (IKVAV), and Dulbecco's Phosphate-Buffered Saline (dPBS) pH buffered with calcium and magnesium. Such bioinks can result in printed constructs that exhibit improved vascularity/perfusability and improved stem cell growth and regulation. Bioink can be formed by vortexing a solution of PEGDA, GelMA, HAMA, LAP, tartrazine, RGD, IKVAV, and/or dPBS at a temperature of, e.g., about 60°C or greater. DLP bioprinting can be carried out layer-by-layer with an average thickness of each layer being between about 25 µm and about 100 µm. Average light intensity emitted during DLP bioprinting can be between about 10 mW/cm2 and about 30 mW/cm2.

SYSTEM, METHOD, AND APPARATUS FOR MOISTURE EVENT DETECTION

Resumen de: US20260204408A1

The present disclosure provides a system for tracking hygiene products, comprising a plurality of hygiene products, each hygiene product having an associated tag, a reader configured to detect the tags associated with the hygiene products, and a point of care unit configured to receive tracking information from the reader. The point of care unit is further configured to track any of the time since a hygiene product was last replaced, moisture events, and rounding checks.

TIME ACTIVITY ESTIMATION ENABLED BY SPATIO-TEMPORAL CONSISTENCY IN MULTI-MODAL QUANTITATIVE SPECT

Resumen de: WO2026151447A1

For SPECT imaging (150) of dynamic processes, extra-modal information (e.g., anatomical) is used in reconstruction (140) of a SPECT volume (e.g., tomographic three-dimensional (3D) representation of the patient). This volume is reconstructed (140) from emissions acquired (110) at different views at corresponding different times. The extra-modal information may be used in combination with the reconstructed volume (122) and treating the detected emissions of the different views as temporal sampling to generate a dynamic volume (e.g., 4D) representation (142). Linear coefficient-based combination of zonal projections of the 3D representation with fitting (130B) to view specific data is used to determine the linear coefficients (132) over time. The linear coefficients (132) are used to gate (140) the 3D representation in forming the 4D representation (142). Unlike planar imaging, the underlying activity may be separated. The dynamic volume representation (142) is provided without requiring a slow dynamic process.

DEVICE AND METHOD FOR PREDICTING EARLY DEMENTIA IN ELDERLY PERSON BY USING ARTIFICIAL INTELLIGENCE

Resumen de: WO2026151252A1

According to one embodiment of the present invention, a device for predicting early dementia in an elderly person by using artificial intelligence comprises: an image data collection unit on which a subject draws an additional picture over an image on which stimulus symbols are printed, and which collects image data; an analysis unit for performing, on the image data, machine learning using a pre-stored artificial neural network model, and analyzing the dementia prediction degree; and an output unit for outputting dementia prediction information about the subject's degree of dementia analyzed by the analysis unit.

IDENTIFIER FOR A MEDICAL DEVICE

Resumen de: US20260204403A1

0000 For identification for medical devices, the medical device is formed by a generic electronics module and a removable identification module. By using an identifier on a removable module, the identifier may be associated with different electronics modules to form the medical device at different times. The removable module may include electronic paper, label, and/or memory for storing and/or displaying information about the medical device. The removable module may allow for settings to be provided for any connected electronics module, avoiding reconfiguring by the user. A service organization does not need to re-ship back repaired components, instead providing a replacement electronics module to form the complete medical device with the user kept identification module.

RECTANGULAR/ELONGATED ARRAY IN ULTRASOUND IMAGING WITH USER GUIDANCE FOR HIGHER RESOLUTION ANATOMICAL VIEW PLANES

Resumen de: WO2026149808A1

The present disclosure may include devices, systems, apparatuses, and methods for capturing improved 2D images of desired view planes. For example, an apparatus is disclosed that includes a rectangular ultrasound array and a processor configured for communication therewith. The processor may be configured to: control the rectangular ultrasound array to obtain 3D ultrasound data of an anatomy of a patient while the rectangular ultrasound array is in a first pose; determine a location of a 2D view plane of the anatomy within a 3D model of the anatomy based on at least the 3D ultrasound data; determine, for the 2D view plane, a first scan angle associated with the first pose of the rectangular ultrasound array; determine, for the first scan angle, a first image quality; and output a screen display comprising the location of the 2D view plane, the first scan angle, and/or the first imaging quality.

DYNAMIC TOOTH CHART AND AUTOMATIC CHARTING

Resumen de: WO2026151619A1

A method is provided for generating and/or displaying a dynamic tooth chart In some cases, the method can include receiving dataset(s) associated with a patient. Each dataset comprises data corresponding to an imaging modality of a plurality of imaging modalities and provides information on a dentition of the patient. The datasets are processed to generate, for each dataset, one or more tooth portions. Each tooth portion comprises an image of one or more teeth of the patient. The one or more tooth portions are arranged into a dental chart. A visualization of the dental chart of the patient is generated and provided to a user device for presentation in a user interface. In some cases, a method can include determining one or more chart annotations can by performing a shape analysis, a teeth arrangement analysis, and/or a material analysis on 3D dental model(s) and/or 2D images of the patient's jaw.

DEFORMABLE VIDEO REGISTRATION

Resumen de: WO2026150414A1

The invention relates to means and methods for a deformable video registration of a three- dimensional virtual representation of an elongated device, having at least one camera thereon, in a three-dimensional virtual representation of a dynamically deforming anatomy, the method comprising: a. obtaining an image captured by said at least one camera; b. correcting a relative location of a virtual camera relative to a virtual anatomy, or vice-versa, based on said obtained image; and c. correcting a tracked deformation of said anatomy based on said corrected relative location.

DEEP BRAIN STIMULATION

Resumen de: US20260199683A1

A method for supporting deep brain stimulation (DBS) programming includes receiving pre-operative magnetic resonance imaging (MRI) data and post-operative computed tomography (CT) data of a patient having an implanted DBS lead and registers the MRI and CT data into a common spatial reference frame. Anatomical and device-related features, including DBS lead placement and one or more neural regions of interest, are extracted from the registered images. A patient-specific electrical conductivity model of brain tissue is generated based on the MRI data. Using the conductivity model and a representation of the DBS lead, electric field distributions corresponding to one or more DBS contact configurations are simulated. The simulated electric field is optimized by determining stimulation parameters that increase electric field exposure within the neural regions of interest while limiting exposure outside those regions. One or more DBS stimulation settings are output for clinical programming of the DBS lead.

MONITORING AND VISUALIZING GAIT OF A USER OF AN ASSISTIVE DEVICE

Resumen de: US20260198849A1

0000 Embodiments disclosed herein provide a mobile device for monitoring and visualizing a gait of a user. The mobile device includes a camera, an I/O interface, a memory comprising an application and a processor connected to the memory. The processor is configured to start a gait session to receive a measurement data from plurality of sensors of the user wearing an assistive device, the gait session initializes the measurement data reception from the plurality of sensors. Further, the processor activates the camera to record a video data of the user concurrently receiving the measurement data from the plurality of sensors during the gait session. The processor applies timestamps to frames of the video data of the user with respect to the measurement data based on the initialization signal to obtain time-synchronized gait visualization data.

METHODS AND APPARATUS FOR AUTOMATED EXTRACTION OF CORONARY ARTERY DISEASE INFORMATION FROM UNSTRUCTURED MEDICAL DATA

Resumen de: AU2024395361A1

Methods and apparatus for extracting coronary artery disease (CAD) information from unstructured medical text are provided. The method includes receiving unstructured medical text, processing the unstructured medical text using one or more trained natural language processing (NLP) models, wherein the one or more trained NLP models are trained to output CAD information, wherein the CAD information includes predicted coronary lesion information, and displaying an indication of the predicted coronary lesion information on a user interface associated with a computing device.

向上された経皮的局所ドラッグデリバリーのためのマイクロニードル粒子

Resumen de: WO2024235974A1

A microneedle particle arranged to be rolled and massaged on a subject's skin (12) to penetrate the stratum corneum (14) is disclosed. The microparticle comprises a support body (20), and a plurality of microneedles (30) protruding from the support 5 body (20), each microneedle comprising a tip (40). The support body (20) maintains the microneedles (30) and tips (40) in a predetermined conformation allowing the microneedle particle to be rolled on the skin. The microneedles have an average tip sharpness radius of less than 20 µm, an average microneedle length of less than 100 µm, and an average tip sharpness to microneedle length ratio of 1:5 to 1:200. 10 Formulations and kits for said use are provided. A microneedle particle manufacturing method using a non-linear two-photon absorption process, a non- therapeutic cosmetic method of skin treatment, and a method of drug delivery through the skin for said microneedle particle are disclosed.

METHODS AND SYSTEMS FOR AI-DRIVEN REFINEMENT OF MENTAL HEALTH DIAGNOSTICS AND PERSONALIZED TREATMENT

Resumen de: US20260204417A1

The present disclosure provides a method of facilitating AI-driven refinement of mental health diagnostics and personalized treatment. The method may include transmitting a prompt data to a user device. Further, the method may include receiving a mental health data from the user device based on the prompt data. Further, the mental health data may be associated with a user. Further, the method may include identifying a demography data based on the mental health data. Further, the method may include determining a diagnostic schema data to provide diagnostic insights based on the demography data. Further, the method may include generating a pre-diagnosis and/or diagnosis report data to provide personalized insights based on the diagnostic schema data and the mental health data. Further, the method may include transmitting the pre-diagnosis and/or diagnosis report data to the user device.

SYSTEMS AND METHODS FOR TRANSPORT AND DISTRACTION

Resumen de: AU2024394477A1

A transport device for increasing biological activity within a patient includes a base including a first end, a second end, an upper surface located between the first end and the second end, and a lower surface located between the first end and the second end, a base anchor configured to statically couple the base to a first portion of a bone of a subject, a translatable anchor configured to engage a growth stimulator, a leadscrew dynamically coupling the base to the translatable anchor, wherein the leadscrew is configured to rotate about a leadscrew axis while substantially maintaining its longitudinal position along the leadscrew axis in relation to the base, such that the growth stimulator, when engaged with the translatable anchor, is capable of independent movement in relation to the base along a stimulation axis that includes at least some transverse displacement with respect to the bone when the base is coupled to the bone via the base anchor, and a screw drive rotatably coupled to the leadscrew and configured to couple to a rotatable mating tool that is configured to rotate the leadscrew via the screw drive.

Neural Network Techniques for Appliance Creation in Digital Oral Care

Resumen de: US20260199058A1

0000 Systems and methods are disclosed for generating a three-dimensional (3D) representation of oral care data for use in oral care treatment. The systems and methods involve receiving an input 3D representation of a patient's dentition and encoding the 3D representation into a lower-dimensional first latent representation using a trained first machine learning (ML) module. Subsequently, a trained second ML module, comprising a trained transformer encoder model or a trained transformer decoder model, is executed to generate a second latent representation using the first latent representation. The second latent representation is then reconstructed into a 3D oral care representation (e.g., a tooth restoration design, an appliance component, a fixture model component, etc.) by a decoder. Finally, the processing circuitry outputs the reconstructed 3D representation of oral care data. These systems and methods enable efficient and accurate generation of oral care data, facilitating improved oral care appliance generation, treatment planning and analysis.

Transformers for Final Setups and Intermediate Staging in Clear Tray Aligners

Resumen de: US20260199057A1

0000 Systems and technique are disclosed for generating transforms and oral care appliances for oral care treatment. The method involves receiving a first three-dimensional (3D) representation of oral care data and utilizing processing circuitry to execute a machine learning (ML) model that includes at least one transformer. The ML model generates at least one transform based on the input data. The processing circuitry applies the generated transform to the first 3D representation, placing it in a desired pose relative to a second 3D representation or a global coordinate system axis. Based on this application, the method further generates aspects of one or more oral care appliances associated with either the first 3D representation or the second 3D representation. These systems and techniques enable the efficient generation of transforms and oral care appliances, facilitating improved treatment planning and customization in oral care applications.

3D FAT TISSUE STRUCTURE, PRODUCED USING LIGHT-BASED STRUCTURING CURING, FOR USE AS A BREAST IMPLANT

Resumen de: US20260199553A1

0000 The invention relates to a 3D adipose tissue scaffold for use as a breast implant for surgical, therapeutic, prophylactic or aesthetic restoration, reconstruction or replacement of human breast tissue, wherein the 3D adipose tissue scaffold comprises a matrix of a biocompatible polymer which is colonized with a plurality of biological cell types, the colonization with the plurality of cell types taking place during the construction of the matrix of biocompatible polymer with the formation of a blood vessel network within the 3D adipose tissue scaffold, characterized in that light-based, structuring curing of a photopolymerizable or photocrosslinkable liquid is used for the construction of the matrix of biocompatible polymer. The invention also relates to the use of a 3D adipose tissue scaffold as a breast implant in humans, wherein the 3D adipose tissue scaffold comprises a matrix of biocompatible polymer which is colonized with a plurality of cell types, wherein the colonization with the plurality of cell types takes place during the construction of the matrix of biocompatible polymer with the formation of a blood vessel structure network within the 3D adipose tissue scaffold, characterized in that light-based, structuring curing of a photopolymerizable or photocrosslinkable liquid is used for the construction of the matrix of biocompatible polymer.

BIG DATA-BASED ARTIFICIAL ORGAN PRODUCTION SYSTEM

Nº publicación: US20260199095A1 16/07/2026

Solicitante:

ALDAVER INC [KR]
ALDAVER INC.

Resumen de: US20260199095A1

The present invention relates to a big data-based artificial organ production system. The artificial organ production system according to the present invention includes: an input unit that receives user's requirements for the artificial organ to be produced as input values; a database unit that stores data necessary for producing the artificial organ; a control unit that produces the artificial organ by inputting the input values into the artificial organ production algorithm learned on the basis of the database unit; and a bioprinter that produces the artificial organ under the control of the control unit.