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人工知能基盤のロボット支援整形外科的運動システム及び方法

Resumen de: WO2025211918A1

Disclosed is an exercise system including: a walking exercise device including an effector having at least one link that drives a pedal on which a patient stands; and a system operation device for controlling a main effector according to a training plan for each individual to conduct walking training for the patient, wherein the system operation device includes: an index prediction unit having an index prediction model for predicting a walk evaluation index of the patient on the basis of basic information including personal information and initial walking state information of the patient; a training planning unit for establishing an individual training plan for each patient on the basis of the predicted waling evaluation index; a training evaluation unit for evaluating a training result on the basis of training result data according to a result of rehabilitation training of the patient performed by the walking exercise unit; and a reporting unit for performing reporting on the training result on the basis of the evaluation of the training result.

一种结合AI智能问诊的儿童穴位物理治疗设备及方法

Resumen de: CN122822280A

0001 本申请涉及智能医疗设备技术领域，公开了一种结合AI智能问诊的儿童穴位物理治疗设备及方法，旨在解决通用型按摩触头无法精准匹配儿童手部穴位，导致力学刺激失焦且易引起儿童抗拒的问题。该方法包括：构建具有柔性仿生手型按摩内芯和气压驱动的物理治疗设备；通过移动端应用程序的症状‑穴位‑按摩方案映射算法，生成并输出穴位治疗方案；驱动气压组件进行充放气，带动按摩触头对特定穴位执行仿生按摩；利用压力传感器与主控电路模块形成闭环控制，自适应调节按摩力度。本申请通过采用上述技术方案，能够实现针对合谷、板门等关键穴位的定向力学刺激，在保障安全性的同时提升穴位物理干预的疗效确定性和儿童的治疗依从性。

一种基于骨粘合剂的3D打印骨修复体及其制备方法

Resumen de: CN122805882A

本发明公开了一种基于骨粘合剂的3D打印骨修复体及其制备方法，属于医用修复材料制备技术领域。所述骨修复体包括可吸收聚合物支撑网及填充于其内部的骨粘合剂，所述骨粘合剂的液相固化液为柠檬酸与丙二酸的混合酸水溶液。本发明还公开了所述骨修复体的制备方法，通过双喷头3D打印技术分别构建支撑网和填充骨粘合剂，并根据修复体尺寸自适应选择是否打印支撑网。本发明利用柠檬酸与丙二酸的协同效应显著提升了骨粘合剂的抗压强度、降解pH稳定性和降解速率适配性，实现了与骨再生周期的精准匹配，可广泛应用于颅骨、颌面、牙槽骨及四肢骨等不同类型骨缺损的个性化修复。

一种光固化PEGDA材料的合成方法及其SLA 3D打印应用

Resumen de: CN122810377A

本发明涉及一种光固化PEGDA材料的合成方法及其SLA 3D打印应用，包括以下步骤：合成PEG和甘油的摩尔比呈预设比值的PEGD线性聚合物，所述预设比值的取值范围为20:80～60:40；对所述PEGD线性聚合物进行纯化；对纯化后的PEGD线性聚合物的末端丙烯酸酯化，以获得能够应用于SLA 3D打印的PEGDA材料，具有使制成的PEGDA材料具备光固化性能、状记忆效应、生物降解性和机械强度，适用于高分辨率的SLA打印的优点。

医疗设备及诊疗系统

Resumen de: CN224796628U

本实用新型公开一种医疗设备及诊疗系统，医疗设备包括设备主体、辅助器件和驱动组件，设备主体的内部形成有安置腔，安置腔具有开口；辅助器件收容在安置腔内，且可沿预设方向经开口向外移出，辅助器件包括打印机；驱动组件设于设备主体，且与辅助器件驱动连接；其中，在确认打印机完成打印后，驱动组件驱动打印机经开口向外移出。本实用新型采用相对简单的结构，实现辅助器件在稳定收纳和精准推送之间的自动切换，有助于提升辅助器件和医疗设备之间的使用品质和使用可靠性。

一种个性化耳廓再造3D生物打印复合墨水

Resumen de: CN122805891A

本发明涉及组织工程及3D生物打印技术领域，具体涉及一种个性化耳廓再造3D生物打印复合墨水。所述复合墨水包括明胶甲基丙烯酰水凝胶基质、脱细胞软骨基质微碎片、仿生增强相、天然可见光交联体系、动态共价交联组分、患者自体耳廓软骨细胞与脂肪来源间充质干细胞，以及负载转化生长因子‑β3的缓释微球。该复合墨水在喷嘴剪切作用下发生剪切变稀，沉积后经405nm可见光交联形成具有弹性、自修复性及可控降解性的耳廓支架，并通过仿生微通道改善内部营养输送。该复合墨水能够适配患者健侧耳廓扫描数据生成的个性化模型，提高复杂耳廓结构的打印精度、细胞存活率和长期形态稳定性，促进软骨基质沉积及新生软骨形成。

一种促成骨分化的3D打印钛合金仿生多孔人工骨及其制备方法和应用

Resumen de: CN122805879A

本发明公开了一种促成骨分化的3D打印钛合金多孔仿生人工骨、制备方法及应用，属于生物医用材料领域。该人工骨由钛金属骨架构成，内部具有相互连通的多孔网状结构；多孔网状结构模仿人体第四腰椎松质骨的三维微观结构设计而来，其平均孔径为60.3‑73.9μm，孔隙率为67.9%‑80.5%。制备方法为获取骨密度恢复较快的第四腰椎断层图像，提取松质骨结构进行三维重建，经选区激光熔化技术打印成型。本发明的特定物理拓扑结构能有效激活骨髓间充质干细胞的Notch2信号通路，诱导成骨分化。应用于临界骨缺损修复时，可增加缺损部位的新骨生成量，提升愈合区域的弹性模量与最大弯曲应力，实现良好的骨整合。

一种基于3D打印技术的原位矿化胶原支架材料及其制备方法

Resumen de: CN122805893A

本申请公开了一种基于3D打印技术的原位矿化胶原支架材料及其制备方法，包括如下步骤：S1：使用有机溶剂溶解胶原，配置成预设浓度的胶原溶液；S2：使用纯化水分别配置预设浓度的钙离子溶液与磷酸根离子溶液；S3：在胶原溶液中分别加入钙离子溶液与磷酸根离子溶液，配置为两种含有不同矿物离子的原位矿化3D打印墨水；S4：装入到不同打印料筒中进行打印，打印结束后将支架置于干燥皿中干燥预设时间；S5：配置预设浓度的交联溶液，将支架浸泡，得到的支架用纯化水洗涤，干燥得到原位矿化胶原支架材料。属于骨植入物技术领域，该结构能够解决现有可降解人工骨材料一般强度较低且没有合适的孔径及孔隙率满足骨细胞爬行替代的问题。

基于患者进展优化正畸治疗

Resumen de: WO2025128745A1

A method is provided for optimizing a dental treatment plan. In some cases, the method can include receiving patient data comprising one or more progress indicators associated with an dental treatment plan, processing the patient data to determine a level of progression associated with the dental treatment plan based on the one or more progress indicators, modifying the dental treatment plan in response to the determined level of progression, and generating a notification of the modified dental treatment plan. In some cases, modifying the dental treatment plan in response to the determined level of progression includes advancing a patient associated with the patient data to a subsequent stage of the dental treatment plan or retaining the patient within a current stage of the dental treatment plan.

中医辨证个性化3D打印支具及制作方法

Resumen de: CN122805416A

本发明涉及一种中医辨证个性化3D打印支具及制作方法，包括：获取患者脊柱侧弯的三维扫描数据和医学影像数据，建立脊柱三维模型；获取患者中医证型信息，确定支具中经络腧穴刺激区的位置、数量和刺激参数，以及支具结构参数、支具压力参数和支具颜色参数；根据脊柱三维模型和确定的参数，建立支具三维模型并进行3D打印，得到支具实体；配置刺激模块并安装；优势：将中医辨证分型信息融入支具设计制造全流程，以辨证结论为统一依据，贯通支具的力学矫正参数、腧穴刺激参数、结构适配参数和外观色彩参数的个性化配置，打破了现有支具单一力学矫正且各模块参数彼此割裂的技术局限，真正实现了辨证施具、因人制宜。

踝关节康复效能评估方法、系统、评估终端及存储介质

Resumen de: CN122805214A

本申请提供一种踝关节康复效能评估方法、系统、评估终端及存储介质，涉及医疗技术领域。通过将权重分配问题建模为序贯决策模型，以当前各维度得分及其变化趋势作为状态输入，以最大化未来一段时间内康复效能指数的累积提升量为优化目标，通过策略梯度算法训练出的策略网络能够根据患者当下的康复态势智能地调整权重分配，使三个维度的权重能够根据患者当前的康复状态及其变化趋势进行自适应调整，实现了评估重点与患者实际薄弱环节的动态对齐。基于三个维度综合确定康复效能指数，为踝关节康复提供了一种多维度量化评估手段，最终生成直观的康复效能提示信息，实现了对踝关节康复进程的客观量化与可视化反馈。

電子目視検査が組み込まれた組み立てライン

Resumen de: CA3030472A1

0001 Methods and systems are disclosed for obtaining a first image of a tray, determining a presence or absence of one or more first patterns in the first image, determining a rotation of each the one or more first patterns in the first image, and performing an action based on the presence or absence and the rotation of the one or more first patterns in the first image. 0002 L'invention concerne des procédés et des systèmes permettant d'obtenir une première image d'un plateau, de déterminer la présence ou l'absence d'un ou de plusieurs premiers motifs dans la première image, déterminer une rotation de chacun des un ou plusieurs premiers motifs dans la première image, et à effectuer une action sur la base de la présence ou de l'absence et de la rotation du ou des premiers motifs dans la première image.

医療システム

Resumen de: US20240306891A1

0000 A system can automatically regulate irrigation, suction, or both, such as during a lithotripsy procedure. The system can include one or more sensors. Processing circuitry can be configured to generate an indication of a level of turbidity of a solution at or near a distal tip of a flexible scope, such as based on one or more signals from the one or more sensors. A control signal can be used to adjust an irrigation flow rate and/or a suction rate at the distal tip of the flexible scope. The level of turbidity can be determined using a sensor to measure electrolytic conductivity of the solution, a sensor to measure electromagnetic induction across a coil at the distal tip of the flexible scope and/or a measure of back reflected light or a measure of absorbed light emitted into the solution by a light source and measured by a light sensor.

TECHNIQUE FOR DEFINING A POSITION OF A MODEL OF AN ANATOMY OF A PATIENT'S DENTAL ARCH WITHIN A GLOBAL REFERENCE FRAME

Resumen de: US20260283759A1

A method for defining a position of an origin of a model of an anatomy of a patient's dental arch (302; 402) within a reference frame (XYZ) comprises receiving a first dataset comprising a surface representation of a surface topology of the patient's dental arch (302; 402) and segmentation lines representing borders between tooth crowns and adjacent soft tissue. A projection of the segmentation line into an occlusion plane (412) is generated. A center of a tooth in the occlusion plane (412) is determined as the centroid of an area bounded by a projected segmentation line. A segment of a parabola is fit to the centroids. An anterior point of the patient's dental arch (302; 402) is identified as the vertex of the parabola. A first translation vector is determined for positioning the anterior point at the origin of a third main component (X) of the reference frame.

Biotinta y andamio para la regeneración de tejido corneal y método de fabricación

Resumen de: WO2026180764A1

The invention relates to a bioink for 3D printing of a scaffold (1) suitable for corneal tissue regeneration, composed of sodium alginate, aldehyde hyaluronic acid, N,O-carboxymethyl chitosan and collagen I, where the collagen I undergoes a preliminary neutralisation process using sodium hydroxide. The present invention also describes a method for the 3D printing of a scaffold (1) suitable for corneal tissue regeneration and a method for sterilising same using ethylene oxide (EtO).

BIOMIMETIC 3D-PRINTED HIERARCHICAL IN VITRO HUMAN SYNOVIUM MODEL FOR ANTI-ARTHRITIS DRUG EVALUATION

Resumen de: US20260286307A1

A bio-printed in vitro three-dimensional (3D) human synovium model, comprising: an upper layer comprising human synovial cells and human macrophages exhibiting a pro-inflammatory phenotype; and a lower layer comprising human macrophages exhibiting an anti-inflammatory phenotype; wherein the model is configured to mimic the inflammatory microenvironment of human synovial tissue. The present invention also discloses a method for constructing an in vitro three-dimensional (3D) human synovium model, comprising the steps of preparing hydrogel cell inks; incorporating one or more human cells exhibiting an anti-inflammatory phenotype into the hydrogel to form at least one layer; incorporating one or more human synovial cells and human cells exhibiting a pro-inflammatory phenotype into the hydrogel to form at least one layer above the anti-inflammatory layer; and performing crosslinking and culturing the hydrogel to establish an inflammatory microenvironment, thereby forming an in vitro 3D human synovium model.

OLIGOMERIC/POLYMERIC PRODUCTS FOR USE AS WATER-SOLUBLE, BIOCOMPATIBLE, BIODEGRADABLE, THREE-DIMENSIONAL (3D) PRINTABLE, AND RADIATION-CURABLE BIOINK

Resumen de: WO2026198014A1

The present invention relates to an oligomeric and/or polymeric product for use as water-soluble, biocompatible, biodegradable, three-dimensional (3D) printable, and radiation-curable bioink.

Verfahren und Rohlinge als Zwischenprodukt zur Herstellung hybrider dentaler Prothesen

Resumen de: DE102025111349A1

Die Erfindung betrifft ein reales sowie ein virtuelles 3D-Formkörperzwischenprodukt (0, 0“), zur Herstellung eines Zwischenproduktes (13, 13“) einer realen oder einer virtuellen Prothese, als auch zur Herstellung einer realen oder virtuellen Prothese (10, 10“). Ferner betrifft die Erfindung ein Verfahren zur Generierung des virtuellen 3D-Formkörperzwischenproduktes (0, 0“) als auch ein Verfahren, insbesondere ein computerimplementiertes Verfahren, zur Herstellung des Zwischenproduktes (13) einer realen Prothese als auch der realen Prothese (10), insbesondere einer realen dentalen Prothese (10). Gleichfalls Gegenstand der Erfindung ist ein Datensatz, des 3D-Datenmodells des virtuellen 3D-Formkörperzwischenproduktes (0“), insbesondere umfassend ein Computerprogrammprodukt zur Herstellung des virtuellen und/oder realen 3D-Formkörperzwischenproduktes (0).

Verfahren zu einer Herstellung einer dentalen Vorrichtung

Resumen de: DE102025111307A1

Die Erfindung geht aus von einem Verfahren zu einer Herstellung einer dentalen Vorrichtung (10, 10', 10''), insbesondere einer Einzelkrone, einer mehrgliedrigen Brücke und/oder eines Aligners, mittels eines Dentalfilamentdrucksystems, wobei in zumindest einem Konvertierungsschritt (12) eine CAD-Datei der dentalen Vorrichtung (10, 10', 10'') mittels einer Recheneinheit (14) in Druckbefehle konvertiert wird und wobei die Druckbefehle mittels der 3D-Filament-Druckvorrichtung (16) in einem Druckschritt (18) ausgeführt werden und die dentale Vorrichtung (10, 10', 10'') gedruckt wird.Es wird vorgeschlagen, dass in zumindest einem Ausrichtungsschritt (20) vor dem Druckschritt (18) eine Ausrichtung der dentalen Vorrichtung (10, 10', 10'') für einen Druck, insbesondere mittels der Recheneinheit (14), insbesondere selbsttätig, bestimmt wird, wobei die Ausrichtung derart gewählt wird, dass eine Kaufläche (22, 22') und/oder eine Kauflächenreferenzfläche (24) quer zu einer Druckebene (26) ausgerichtet ist.

REFRESH SCHEME WITH SAME TIER ACTIVATION

Resumen de: US20260290423A1

0000 Apparatuses, systems, and methods for a refresh scheme that refreshes word lines in a same tier in 3D-DRAM. The 3D memory device includes multiple memory patches each of which includes a 3D array of memory cells arranged at the intersection of word lines running in a first direction, local digit lines (LDLs) running in a second direction, and global digit lines (GDLs) running in a third directions. The 3D memory array may be refreshed on a word line-by-word line basis as part of a refresh operation. During the refresh operation, one or more word lines may be refreshed in the 3D memory device. The word lines being refreshed may all be at a same tier of the 3D memory device. The tier may represent the depth at which the refreshed word line exists within a stack of word lines in the 3D memory array.

ROBOTS SELF-DIRECTED BY QUANTUM COMPUTING AND CLASSICAL ALGORITHMS FOR AUTONOMOUS PHYSICAL PROCEDURES IN MEDICAL, DENTAL, COSMETIC, DERMATOLOGY, OPHTHALMOLOGY, AND VETERINARY APPLICATIONS

Resumen de: WO2026198182A1

Robots self-directed by quantum computing and classical algorithms performing autonomous physical procedures in the medical, dental, cosmetic, ophthalmology, and veterinarian professions without guidance, or intervention by human operators. The system relies on comparisons of two data pools: one for real time patient data and the other archived patient data from prior patients. The comparisons are in image data, measurement data, and physical medical procedure data.

GENERATING REALISTIC DENTAL TREATMENT IMAGES USING 3D FACIAL AND DENTAL MODELS

Resumen de: US20260283760A1

0000 A method includes obtaining a 3D head model including a depiction of a current head of a patient; obtaining a first 3D dentition model including a depiction of the current dentition of the patient and a second 3D dentition model including a depiction of an altered dentition of the patient; registering the first 3D dentition model to the 3D head model; generating one or more first images of the 3D head model in one or more poses and generating one or more second images of the second 3D dentition model corresponding to the one or more poses based at least in part on a result of the registering; and generating modified versions of the one or more first images by replacing the current dentition of the patient with the altered dentition of the patient from the one or more second images.

SYSTEM AND METHOD FOR GENERATING A THREE-DIMENSIONAL DIGITAL PATIENT MODEL OF A PATIENT'S ORAL ANATOMY HAVING AN EDENTULOUS JAW PORTION

Resumen de: US20260289928A1

0000 Computer-implemented method, computer program product and computing system (100) for generating a three-dimensional digital patient model (210) of a patient's oral anatomy with the patient (1) having a first at least semi-edentulous jaw arch, and having at least one first dental implant placed in the jawbone of said first at least semi-edentulous jaw arch, and having a prosthesis applied to the at least semi-edentulous jaw arch. The system receives a second three-dimensional intra-oral surface scan dataset (202) obtained from the patient's jaw arch opposing the at first least semi-edentulous jaw arch in a non-occlusion state and a third dataset (203) comprising representations of both jaw arches in an occlusion state. A fourth three-dimensional intra-oral surface dataset (204) of at least portions of the gingiva surface (204-g) in said first at least semi-edentulous jaw arch and with surface information of a first implant head interface (204-1, 204-2, 204-3, 204-4) of the at least one first implant located in the at least semi-edentulous jaw arch is received. A fifth three-dimensional 4π surface dataset (205) of the prosthesis is received with surface information of at least one first abutment interface (205-1, 205-2, 205-3, 205-4) configured to engage positively with the implant head interface (204-1, 204-2, 204-3, 204-4). The digital patient aligns the fourth three-dimensional intra-oral surface dataset (204) and the fifth three-dimensional 4π surface dataset (205

ENAMEL WIDTH AND DENTIN SHAPE FROM NEAR INFRARED SCANS

Resumen de: US20260283577A1

Systems, apparatuses, and methods disclosed herein are directed to systems, methods, and apparatuses for enabling the determination of enamel width and dentin shape and location from near infrared and 3D surface scan data for use in treating a patient’s dentition.

FUCOIDAN HYDROGEL FOR TISSUE REGENERATION

Nº publicación: WO2026198933A1 24/09/2026

Solicitante:

THE BOARD OF REGENTS OF THE UNIV OF TEXAS SYSTEM [US]
THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM

Resumen de: WO2026198933A1

Disclosed herein are hydrogels comprising functionalized fucoidans and methods of use thereof. Specific disclosures include hydrogels comprising oxidized fucoidans crosslinked with hydrazone or imine bonds and methods of treating cancer or wounds with the same. Also disclosed are methods of bioprinting with fucoidan hydrogels.