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3D打印正畸牙科矫治器的支撑结构及其制造方法

Resumen de: WO2024216245A1

The present disclosure provides a support of a 3D printed orthodontic dental appliance is provided. The orthodontic dental appliance includes a shell structure defined by an inner contour surface and an outer contour surface. The support comprises: a middle support including a middle support base mesh and a plurality of middle support struts and a main support configured to connect the middle support to a build platform of a 3D printing device used to print the orthodontic dental appliance. One end of each middle support strut of the plurality of middle support struts is connected to the orthodontic dental appliance at a junction of the inner contour surface and the outer contour surface, and the other end of the middle support strut is connected to a rim of the middle support base mesh.

用于治疗骨不连的骨整合式可降解硅胶支架及其制备方法

Resumen de: CN121041523A

本发明公开了用于治疗骨不连的骨整合式可降解硅胶支架及其制备方法，涉及医疗植入材料技术领域，该制备方法包括：使含氢硅油与烯丙基缩水甘油醚在铂催化剂作用下发生硅氢加成反应，生成含环氧基团硅油，随后在催化剂作用下使环氧基团开环，得到侧链含磷酸酯基团的硅油；将端羧基聚乳酸‑乙醇酸共聚物与侧链含磷酸酯基团的硅油混合，在缩合剂和催化剂作用下进行缩合反应，得到PLGA‑P‑PDMS‑PLGA三嵌段共聚物；将三嵌段共聚物、反应性稀释剂、光引发剂和无机增强填料混合制得3D打印浆料；使用光固化3D打印技术，根据设定的打印参数，将打印浆料打印成所设计的骨整合支架。通过本发明赋予了材料本征成骨活性，实现了生物活性、形状记忆功能与力学支撑的统一。

全光纤一体式探测消融诊疗仪及制备方法

Resumen de: CN121040956A

本发明公开了一种全光纤一体式探测消融诊疗仪及制备方法，属于光纤超声传感器与激光消融器领域。包括双包层光纤、介质膜、传感腔、微聚焦锥。双包层光纤用于探测光及消融激光的传输，介质膜和传感腔共同形成法布里珀罗（Fabry‑Pérot,FP）腔以传感超声信号，微聚焦锥提供超声聚焦的作用。本发明解决了现有光纤探测消融器件依赖多纤、结构复杂的问题，并解决了现有空心悬臂结构光纤超声传感器灵敏度较低、频带低的问题。

一种施源器及其制备方法

Resumen de: CN121041609A

本发明属于近距离放射治疗医疗器械技术领域，尤其涉及一种施源器及其制备方法，施源器采用3D打印技术制备，其原料各组分配比以质量百分比计，Cu：13‑15％，Zr：8‑10％，Mo：8‑10％，Nb：6‑9％，Sn：2.5‑3.5％，Si：0.5‑1.5％，余量为Ti。本发明通过添加Zr、Mo、Nb、Sn等低磁化率元素，将钛合金的磁化率降至纯钛磁化率的1/3，形成一种β相钛合金，再利用3D打印工艺和热等静压工艺制备成型为含ω相的钛合金施源器，其磁化率更小，使MRI成像伪影面积减少，源到位精度更高，降低了对危及器官的不利影响。

APPARATUS AND METHOD FOR 3D PRINTING PILLS WITH CUSTOM PROPERTIES

METHOD FOR GENERATING A PARTIALLY-CURED ITEM, A PARTIALLY-CURED ITEM AND A CURED OBJECT

Resumen de: EP4578633A2

The invention relates to a method for partial curing of an initial photoreactive material for 3D printing, comprising the steps of:a) providing an item (1) comprising the initial photoreactive material for 3D printing,b) a partial irradiation step comprising irradiating at least one curing section (20) of the initial photoreactive material for 3D printing of the item with a curing irradiation, yielding at least one cured section (120) of a partially-cured item (10), and at least one semi-curing section (40) of the initial photoreactive material of the item is irradiated with a semi-curing irradiation, yielding at least one semi-cured section (140) of the partially-cured item.

耳模制造方法、装置、系统、设备及存储介质

Resumen de: CN121018947A

本申请提供了一种耳模制造方法、装置、系统、设备及存储介质，涉及生物医疗技术领域，本申请预先对目标对象的耳郭取模得到耳郭反向模型，该耳郭反向模型真实表达了耳郭的所有曲面信息，通过扫描该耳郭反向模型得到三维点云数据，并基于三维点云数据构建得到的数字化耳郭正向模型，消除了耳部隐蔽曲面轮廓对点云数据采集的影响，有效实现了对耳郭完整曲面的数字化提取，提高了数字化构建实现耳模的精度，从而保证了数字化耳模与目标人员的耳部的契合度，并依据预设和提取耳郭的穴点信息，进行开孔，然后进行数字化耳模的实物打印，进行适合佩戴，方便进行个性化移动化诊治调理，实现了耳模数字化构建和可移动个性诊治调理的创新全流程。

一种钛基复合材料的制备方法

Resumen de: CN121023285A

本发明公开了一种钛基复合材料的制备方法，该方法包括以下步骤：一、将氧化石墨烯分散液加入聚乙烯吡咯烷酮溶液中混合均匀，滴加硝酸银溶液进行自发反应，得到氧化石墨烯/纳米银复合粉末溶液；二、在氧化石墨烯/纳米银复合粉末溶液中加入钛或钛合金粉末，加热并进行超声机械搅拌，干燥后得到氧化石墨烯/纳米银+钛混合粉末；三、将氧化石墨烯/纳米银+钛混合粉末进行3D打印，得到钛基复合材料。本发明的制备方法通过在钛基表面构建氧化石墨烯和纳米银的共分散纳米结构，得到的钛基复合材料具有晶粒细化、高抗菌性、高耐磨性及高综合力学性能的特点，适用于医用钛及钛合金材料技术领域。

适用于DLP 3D打印技术的齿科修复用复合材料及其制备方法

Resumen de: CN121015460A

本发明属于齿科陶瓷材料技术领域，具体涉及适用于DLP 3D打印技术的齿科修复用复合材料及其制备方法。所述的齿科修复用复合材料包括以下重量份数的原料：聚硅氮烷陶瓷先驱体粘结剂：30‑50份；氧化锆：60‑90份；光引发剂：3‑7份；热引发剂：2‑5份；分散剂：2‑6份；流变剂：1‑5份；硅烷偶联剂：3‑8份；烧结助剂：5‑10份；采用聚硅氮烷先驱体材料，通过光固化精确成型，再经热处理后可控转化为无机陶瓷，兼具有机物的加工性与陶瓷的高耐温、高稳定性，克服了传统有机粘结剂在高温下易分解、收缩大、强度不足的问题，为高性能陶瓷器件制备提供了新材料基础。

交联剂和组合物

Resumen de: US2024352174A1

The present disclosure provides cross-linker compounds that can produce desirable polymeric materials, polymer compositions, and/or photo-curable resins. Further provided herein are methods of producing cross-linker compounds, compositions, resins, devices, and polymeric materials. Also provided herein are methods of using cross-linker compounds, resins, and polymeric materials for the fabrication (e.g., via 3D printing) of medical devices, such as orthodontic appliances.

复合3D环保打印材料的人体肋骨骼替代物制造方法、设备、存储介质

Resumen de: CN121018950A

本发明涉及复合3D环保打印材料的人体肋骨骼替代物制造方法、设备、存储介质，包括：步骤S100.基于患者受伤处的肋骨扫描，输出肋骨数据；步骤S200.在医学图像处理软件中基于所述肋骨数据生成肋骨三维模型；步骤S300.通过三维建模软件对肋骨三维模型进行优化，所述优化至少包括模型预处理、切片参数调整、打印路径规划和填充策略；步骤S400.将聚乳酸与连续纤维通过熔融堆叠形成复合材料，复合材料作为人体肋骨替代物的3D打印材料；步骤S500.采用3D打印技术对所述肋骨三维模型进行打印；步骤S600:对打印的人体肋骨骼替代物进行力学实验测试。

3차원 스크린-인쇄된 작업편을 생산하기 위한 장치, 및 이를 위한 방법

Resumen de: WO2024188676A1

The invention relates to an apparatus for producing three-dimensional screen-printed workpieces, in particular a 3D screen printing installation, said apparatus comprising: a printing device for the layer-by-layer production of at least one screen-printed workpiece in a plurality of printing operations; and a transport device for the automated transport of at least one screen-printed workpiece and/or a workpiece carrier to and/or from the printing device, the transport device having a support portion for at least interlockingly receiving a workpiece carrier.

患者の口腔内の歯科的状況を治療する方法における使用のための硬化性組成物

Resumen de: CN120187382A

The present invention relates to a curable composition for use in a method of treating a dental condition in the oral cavity of a patient, the curable composition comprising a radiation curable component; a photoinitiator that exhibits absorption in the ultraviolet light region and exhibits absorption in the visible light region, the absorption in the ultraviolet light region being stronger than the absorption in the visible light region; optionally, a filler; optionally, an additive; the method comprises the steps of: layer-by-layer manufacturing of a dental or orthodontic article using radiation having a wavelength in the region of the ultraviolet light; attaching the dental or orthodontic article to a surface of hard dental tissue or dental material; radiation having a wavelength in the visible light region is applied to the dental or orthodontic article.

Chemin d’air de ventilateur médical

Resumen de: FR3162365A3

Titre de l’invention Chemin d’air de ventilateur médical L’invention concerne un procédé de fabrication d’un chemin de gaz, de préférence d’air, pour ventilateur médical comprenant un ensemble de conduits ou de tronçons de conduits de gaz en communication fluidique les uns avec les autres. Au moins une partie de l’ensemble de conduits ou de tronçons de conduits de gaz est réalisée en mettant en œuvre un procédé de fabrication additive. Figure de l’abrégé : Figure 1

3차원 스크린-인쇄된 작업편을 생산하기 위한 장치, 및 이를 위한 방법

Resumen de: WO2024188675A1

The invention relates to an apparatus for producing three-dimensional screen-printed workpieces, in particular a 3D screen printing installation, said apparatus comprising: a printing device for the layer-by-layer production of at least one screen-printed workpiece in a plurality of printing operations; and a drying device which is designed to dry at least one screen-printed workpiece and to simultaneously cool a workpiece carrier that carries the screen-printed workpiece to be dried.

ORAL DRUG DOSAGE FORMS FOR STOMACH RETENTION

Resumen de: US2025360081A1

Provided herein are drug dosage forms designed to provide a desired retention in an individual based on geometric differences between a pre-administration and post-administration state of the dosage form. In certain aspects, provided are oral drug dosage forms comprising a swellable and expandable material configured, upon swelling or expanding, to drive expansion of the overall size of the oral drug dosage forms such that the oral drug dosage forms are retained in the stomach for a desired period of time. In certain other aspects, provided is directed to components useful for the oral drug dosage forms taught herein. In certain other aspects, provided is directed to methods of designing, methods of making, such as involving three-dimensional (3D) printing, injection molding, ultrasonic welding, or any combination thereof, commercial batches, and methods of delivering a drug to an individual comprising administering an oral drug dosage form taught herein.

ADDITIVELY MANUFACTURED APPLIANCES WITH CELLULAR STRUCTURES

Resumen de: US2025359967A1

Intraoral appliances and associated systems are provided. In some embodiments, an intraoral appliance includes a 3D printed body composed of a plurality of additively manufactured layers. The 3D printed body can include a first cellular structure located at one or more first areas of the intraoral appliance, the first cellular structure corresponding to a first stiffness, and a second cellular structure located at one or more remainder areas of the intraoral appliance, the second cellular structure corresponding to a second stiffness less than the first stiffness.

DENTAL DEVICE MANUFACTURING SYSTEM AND METHOD

Resumen de: US2025359966A1

A manufacturing system and method obtain a first digital model of teeth, create a modified digital model of the teeth by adding a locator feature to the first digital model of the teeth, and create a physical model of the teeth based on the modified digital model. A portion of the physical model is created based on the locator feature. A dental aligner device is formed on the physical model of the teeth with extraneous material of the dental aligner device extending away from the dental aligner device. The extraneous material is removed from the dental aligner device from the physical model of the teeth. The forming of the dental aligner device and/or the removing of the extraneous material is performed by positioning the physical model using the locator feature.

DEVICES AND METHODS FOR STENT GRAFT EXTRACTION

Resumen de: US2025360010A1

A method of extracting an implant from a vessel includes inserting an extraction device into the vessel. The extraction device includes a hollow body having a cylindrical portion and a bellowed portion. An inner diameter of the bellowed portion increases toward an end of the hollow body. The method also includes sliding the extraction device over an outer surface of the implant such that the hollow body slides between a vessel wall and the implant to move the implant from a deployed position to a non-deployed position within the hollow body. The method can also include removing the extraction device and the implant from the vessel.

MANUFACTURING PROCESSES FOR BIOPOTENTIAL-BASED WRIST-WEARABLE DEVICES AND RESULTING MANUFACTURED BIOPOTENTIAL-BASED WRIST-WEARABLE DEVICES

Resumen de: US2025362752A1

A wrist-wearable device is described herein. The wrist wearable device includes a first skin-contact portion. The first skin contact portion (i) is coupled with a first set of biopotential-signal sensors for detecting first biopotential signals that are provided to a first flexible printed circuit board, and (ii) is coupled with an elastic material that extends beyond an end of the first skin-contact portion. The wrist wearable device includes a second skin-contact portion that is separated from the first skin-contact portion by a capsule structure. The second skin-contact portion is (ii) coupled with a second set of biopotential-signal sensors for detecting biopotential signals that are provided to a second flexible printed circuit board, and (ii) is coupled with a receiving loop for receiving the elastic material to affix the band to a body part of a wearer of the wrist-wearable device.

REINFORCED ENGINEERED CELLULARIZED-TISSUE

Resumen de: US2025361480A1

A method for generating reinforced engineered cellularized construct, which utilizes a biocompatible small-molecule reinforcing agent that do not affect the viability of the cells, a reinforced engineered cellularized construct obtained thereby and used the engineered cellularized construct are provided.

BIOSYMBIOTIC SYSTEMS FOR CHRONIC LONG-RANGE MONITORING OF BIOSIGNALS IN LIMITED RESOURCE SETTINGS

Resumen de: AU2024273563A1

The present disclosure provides a wearable article including a 3D printed base, 3D printed antenna ground plane structure and a 3D printed a dipole antenna structure, wherein the base, ground plane structure and dipole antenna structure comprises a 3D printed mesh which is formed of a stretchable elastomeric polymer material. The wearable article also includes signal transmission and power harvesting circuitry comprising duplexing circuit to transmit and receive data and to receive wireless power from a power transmission unit.

ZINGEROL-BASED BIODEGRADABLE POLYESTERS AND 3D-PRINTABLE PHOTOPOLYMERIZABLE COMPOSITIONS, METHODS OF PREPARATION, AND USES THEREOF

Resumen de: US2025361358A1

The present invention provides novel polymeric materials for biomedical applications, derived from plant-derived phenolic diols, primarily zingerol. Two material classes are disclosed. First, biodegradable polyesters using said diols, are synthesized via solvent/catalyst-free melt polycondensation. These exhibit tunable mechanical properties, shape memory, antibacterial activity, and biocompatibility. Second, photopolymerizable zingerol derivative monomers or crosslinkers, are formulated into resins for 3D printing. Resulting 3D objects offer tailored mechanics, biodegradability, excellent shape memory, cytocompatibility, hemocompatibility, and potent antioxidant, antibacterial, and anti-biofilm functions. Methods for preparing both polymer types and their derivatives, alongside uses in tissue engineering and medical implants, are described.

3D PRINTING OF ORGANOID SLURRIES

Resumen de: WO2025245459A1

A method for preparing a tissue, comprising depositing a cell bioink in a biocompatible matrix to form a printed cell structure in the biocompatible matrix; and allowing the printed cell structure to incubate in the biocompatible matrix for a time sufficient for at least a portion of cells of the printed cell structure to develop into a contiguous tissue before removing the printed cell structure from the biocompatible matrix; wherein the biocompatible matrix has a yield stress greater than a yield stress of the cell bioink, prior to depositing the cell bioink in the biocompatible matrix, and the biocompatible matrix optionally comprises a rheological modifier.

PART FOR COVERING A BONE DEFECT

Nº publicación: WO2025242824A1 27/11/2025

Solicitante:

GLAD MEDICAL [FR]
GLAD MEDICAL

Resumen de: WO2025242824A1

The present invention relates to a method for manufacturing a covering part for a device intended for bone regeneration, in order to cover a bone defect in a patient, which method comprises the steps of a) recording a set of data representative of the stated bone defect in three dimensions; b) designing the covering part using this set of data, which covering part has a wall opposite the bone defect and a wall facing the bone defect, and which covering part is able to be fastened in place on a bone by at least one fastening means; and c) manufacturing the covering part, wherein the covering part is made from a resorbable polymer by 3D printing, has microperforations, and has a thickness of between 0.8 and 1.5 mm.