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一种具有仿生多孔结构的人工血管及其制备方法

Resumen de: CN122701932A

本发明提供了一种具有仿生多孔结构的人工血管，所述的人工血管的外表面具有多个凹陷状微孔，所述人工血管的基材为聚(巯丙基甲基硅氧烷‑二甲基硅氧烷)和乙烯端聚二甲基硅氧烷。本发明还提供了上述具有仿生多孔结构的人工血管的制备方法，以聚(巯丙基甲基硅氧烷‑二甲基硅氧烷)和乙烯端聚二甲基硅氧烷为基材，随后依次加入光引发剂和致孔剂并混匀，利用SLA光固化技术将上述混合材料打印成型，最后加以清洗和浸泡以去除未固化材料并溶出聚乙二醇羧酸。本发明制备的具有仿生多孔结构的人工血管具有微米级或纳米级多孔网络，同时具备高精度、良好的力学匹配度和优异的生物相容性。

单宁酸功能化的双网络水凝胶、其复合材料及3D打印软骨修复补片

Resumen de: CN122701936A

本发明公开了一种单宁酸功能化的双网络水凝胶、其与聚己内酯的复合材料及双喷头3D打印软骨修复补片。所述水凝胶由甲基丙烯酸明胶光交联第一网络和氧化葡聚糖席夫碱交联第二网络构成，并均匀分散有单宁酸，还可负载TGF‑β1、BMP‑2等生长因子。该水凝胶具有多孔结构，单宁酸的引入不仅赋予主动抗炎功能，还提高了水凝胶的力学性能，杨氏模量接近天然软骨。将水凝胶与PCL共混得到第一墨水（复合材料），另以纯水凝胶作为第二墨水，通过双喷头熔融沉积3D打印一体成型制备包含PCL支撑层和水凝胶活性层的仿生软骨补片。体内实验表明，该补片能够有效抑制IL‑1β、IL‑6、TNF‑α等炎症因子，显著促进软骨缺损修复。

骨固定装置

Resumen de: EP4799579A1

A bone anchoring device for coupling a rod to bone is provided, the bone anchoring device including an anchoring element (1) comprising a shank (2) for anchoring in bone and a head (3), a receiving part (5) having a first end (5a) and a second end (5b), a channel (54) for receiving the rod (100), a passage (51) extending from the first end to the second end, the passage (51) defining a central axis (C), and an accommodation space (53) for accommodating the head (3) of the bone anchoring element (1), a pressure element (6) configured to be arranged in the passage (51) and to encompass the head (3) laterally and from a free end of the head (3) to exert pressure onto the head (3) when the head (3) and the pressure element (6) are in the receiving part (5) such that the head (3) is pivotable with respect to the receiving part (5) and can be locked at an angle relative to the receiving part (5); wherein the anchoring element comprises a first cooperating surface (30) and the receiving part comprises a protrusion (57) at an inner wall of the accommodation space (53) providing a second cooperation surface (57a) which cooperates with the first cooperating surface (30) to limit pivoting of the head (3) to a single plane.

脊柱置钉术前规划质控方法、电子设备及计算机存储介质

Resumen de: CN122140368A

The invention provides a preoperative planning quality control method for spinal screw placement, electronic equipment and a computer storage medium, and the method comprises the steps: constructing a boundary model of key risk objects such as pedicle cortex, canalis spinalis, foramen intervertebralis and superior zygopophysis articular surfaces, and calculating quantitative indexes such as a minimum safety distance, a predicted puncture amount and a puncture direction in combination with preoperative screw planning data; and the structured feature vector and the planning channel local image feature are fused and input into a risk assessment model to output a risk assessment result, so that the screw placement potential safety hazard can be accurately identified for complex cases such as pedicle morphological variation, degeneration or deformity, and the defect that an existing planning system lacks a quantitative quality control and grading early warning mechanism is overcome. A high-risk planning scheme can be prompted in time, an objective basis is provided for path correction, and the accuracy, safety and normalization of preoperative planning of spinal screw placement are improved.

血圧を制御するためのシステム及び方法

Resumen de: CN111989035A

A system for controlling blood pressure includes a wearable interface having an internal contact surface, the wearable interface configured to at least partially encircle a first portion of a first limb of a subject, a sensing module carried by the wearable interface and configured to determine at least a change in blood pressure of the first limb of the subject, and an energy application module carried by the wearable interface and configured to apply energy of two or more types to the first limb of the subject.

SYSTEM FOR FORMING A COSMETIC COMPOSITION AND SKIN CARE MANAGEMENT SYSTEM

Resumen de: US2018284729A1

0001 A skin care system and method for managing a skin care system. The skin care system includes circuitry to receive skin information from a user. The circuitry determines treatable skin conditions based on the skin information. The skin care system generates severity information and cosmetic formulation compatibility information based on the treatable skin conditions. The skin care system is further able to virtually display user-specific compatible cosmetic formulations based on at least one parameter associated with the severity information and cosmetic formulation compatibility.

ユーザのために最適化された警告を提供するためのシステム及び方法

Resumen de: US2017311904A1

0001 Systems and methods are disclosed that provide smart alerts to users, e.g., alerts to users about diabetic states that are only provided when it makes sense to do so, e.g., when the system can predict or estimate that the user is not already cognitively aware of their current condition, e.g., particularly where the current condition is a diabetic state warranting attention. In this way, the alert or alarm is personalized and made particularly effective for that user. Such systems and methods still alert the user when action is necessary, e.g., a bolus or temporary basal rate change, or provide a response to a missed bolus or a need for correction, but do not alert when action is unnecessary, e.g., if the user is already estimated or predicted to be cognitively aware of the diabetic state warranting attention, or if corrective action was already taken.

用于控制流体流的装置

Resumen de: NZ626630A

A peristaltic pump (719), and related system method are provided. The peristaltic pump includes a cam shaft, first and second pinch-valve cams (720, 726), first and second pinch-valve cam followers, a plunger cam (722), a plunger-cam follower, a tube receiver, and a spring-biased plunger (723, 724, 725). The first and second pinch-valve cams (720, 726) are coupled to the cam shaft. The first and second pinch-valve cam followers each engage the first and second pinch-valve cams, respectively. The plunger cam (722) is coupled to the cam shaft. The plunger-cam follower engages the plunger cam. The tube receiver is configured to receive a tube (728). The spring-biased plunger is coupled to the plunger-cam follower such that the expansion of the plunger cam along a radial angle intersecting the plunger-cam follower as the cam shaft rotates pushes the plunger cam follower towards the plunger and thereby disengages the spring-biased plunger from the tube. A spring coupled to the spring-biased plunger biases the spring-biased plunger to apply the crushing force to the tube (728). In other embodiments the plunger may be pivotally mounted to the pump housing.

内腔弁留置患者の結果予測

Resumen de: WO2023069978A1

Various aspects of methods, systems, and use cases may be used to train a model to determine whether a patient is a candidate for receiving an endoluminal valve based on collateral ventilation data. A method may include receiving sensor data based on pressure or airflow at a target portion of a lung of a patient that is occluded from receiving air via a breathing airway of the lung. The method may include training a machine learning model, based at least in part on training data (e.g., based on the sensor data), to predict patient breathing outcomes via an indication of whether collateral ventilation is present in a particular patient target lung portion.

情報提供装置、採血システム、情報提供方法およびプログラム

Resumen de: JP2026141823A

0001 【課題】ドナーの健康意識向上と採血リピートの促進とを図れる情報提供装置、採血システム、情報提供方法およびプログラムを提供する。 【解決手段】献血施設１００において、採血システム１０の情報提供装置１６は、採血装置１２のセンサユニット１４（１以上のセンサ）から出力される検出信号に基づいて、ドナーから採血される血液の状態を示す血液情報を取得する血液情報取得部３４と、血液情報に基づいてドナーの健康状態を判定する判定部４０と、判定部４０による判定の結果を示す情報をドナーに提供するための処理を実行する情報提供処理部４２と、を備える演算部３２を有する。 【選択図】図１

A HOOKAH DEVICE

Resumen de: WO2022129907A1

A mist inhaler device (200) for generating a mist comprising a therapeutic for inhalation by a user. The device comprises a mist generator device (201) and a driver device (202). The driver device (202) is configured to drive the mist generator device (201) at an optimum frequency to maximise the efficiency of mist generation by the mist generator device (201).

3D Hydrogel for controlled release of biopharmaceuticals in the gastrointestinal tract using 3D printing and method for manufacturing the same

Resumen de: KR20260134035A

본 발명은 펙틴 및 키토산으로 구성된 고분자 전해질 복합체를 포함하는 파트 재료 조성물과 이온 경화제 및 나노셀룰로오스를 포함하는 서포트 재료 조성물을 이용한 3D 프린팅용 생체소재 잉크 조성물, 바이오의약품을 탑재하기 위한 방출 거동이 조절된 다중 구획 구조 약물 전달 시스템 및 이의 제조 방법에 관한 것이다. 구체적으로, 파트 재료로는 펙틴-키토산 하이드로젤을 이용하여 단일 생체소재의 단점을 보완하였고, 형태 유지력이 강한 나노셀룰로오스와 이온 경화제(피틴산, 염화칼슘)을 이용하여 자유형상 3D 프린팅에 최적화하였다. 이를 통해, 위에서 바이오의약품을 보호하고 소장에서의 서방형 방출 및 방출 거동을 정밀하게 조절할 수 있는 바이오의약품 경구 투여용 개인 맞춤형 제제를 제공할 수 있다.

具有同时发生的着陆区调整和可视化的用于支架规划的血管内成像

Resumen de: WO2025168460A1

A system includes a processor circuit configured to control an intravascular imaging catheter to obtain intravascular images while the catheter is moved through a blood vessel of a patient, and output a screen display for stent planning. The screen display includes a visual representation of the blood vessel and a virtual stent overlaid in a first position on the visual representation. The processor circuit receives a first user input to move the virtual stent from the first position to a different, second position on the visual representation, and updates the screen display. The updated screen display includes the visual representation of the blood vessel and the virtual stent overlaid in the second position on the visual representation. The length of the virtual stent is the same in the first position, in the second position, and while the virtual stent moves from the first position to the second position.

情報処理装置、画像生成方法、及び画像生成プログラム

Resumen de: US20260253275A1

An information processing device includes a digitizing unit for generating numerical data indicating a time-series change of a biological signal from first image data indicating a waveform of the biological signal, and an image generation unit for generating second image data indicating a waveform of the biological signal by using the generated numerical data. The generated second image data can be used as training data for machine learning or can be used for decision making by a medical worker in diagnosis of a subject to be measured for the biological signal.

近植入期参数转换

Resumen de: US20250253052A1

Systems and methods to improve patient monitoring and device operation during a near-implant time period are disclosed, including determining a representative value of received physiologic information of a patient sensed by an implantable medical device implanted in the patient, determining a hybrid or relative baseline for the patient using the received physiologic information, and determining an indication of patient condition as a weighted function of (1) the representative value of the received physiologic information, (2) an absolute baseline, and (3) the hybrid or relative determined relative baseline, with a weight of at least one the determined absolute baseline or the determined relative baseline changing with time relative to a time of implant of the implantable medical device.

近植入期心力衰竭监测

Resumen de: US20250249263A1

Systems and methods to improve patient monitoring and device operation during a near-implant time period are disclosed, including determining a representative value of physiologic information of a patient sensed in a near-implant time period after implant of an implantable medical device in the patient, determining an absolute or hybrid baseline corresponding to the near-implant time period using information from at least one of an imputed baseline corresponding to a pre-implant time period preceding implant of the implantable medical device in the patient or an initial value of the received physiologic information of the patient in an initial portion of the near-implant time period, and determining an indication of patient condition as a function of the determined representative value and the determined absolute or hybrid baseline.

提高输注设备对医学测试要求的合规性的设备、系统和方法

Resumen de: WO2025136385A1

An infusion device includes a fluid pump and a processor. The processor is configured to determine an amount of fluid pumped by the fluid pump or an amount of time the fluid pump has pumped the fluid. The processor is also configured to determine that the amount of fluid satisfies a volume threshold or that the amount of time satisfies a duration threshold. Additionally, the processor is configured to, responsive to determining that the amount of fluid satisfies the volume threshold or that the amount of time satisfies the duration threshold, electronically transmit a request for a medical test and initiate a timer. Further, the processor is configured to determine an adjustment-delay threshold prior to an initiation or a completion of the medical test. Moreover, the processor is configured to reduce an operating speed of the fluid pump when the timer satisfies the adjustment-delay threshold.

用于从非结构化医学数据中自动提取冠状动脉疾病信息的方法和装置

Resumen de: US20250191762A1

extracting coronary artery disease (CAD) information from unstructured medical text are provided. The method includes receiving unstructured medical text, processing the unstructured medical text using one or more trained natural language processing (NLP) models, wherein the one or more trained NLP models are trained to output CAD information, wherein the CAD information includes predicted coronary lesion information, and displaying an indication of the predicted coronary lesion information on a user interface associated with a computing device.

3D Method for manufacturing ceramic slurry for photocurable 3D printing

Resumen de: KR20260133711A

본 발명은 광경화성 3D 프린팅용 세라믹 슬러리의 제조방법에 관한 것으로, 더욱 상세하게는 세라믹 또는 글라스 세라믹 분말을 사용하여 치과 보철물이 자연치와 유사한 심미성을 나타낼 수 있으며, 나아가 비반응성 희석제를 포함하여 세라믹 또는 글라스 세라믹 분말을 고함량으로 포함하면서도 저점도의 슬러리 제조가 가능하고, 이와 같이 제조된 슬러리는 3D 프린팅을 이용한 성형이 용이하며, 3D 프린팅 시 높은 품질의 3차원 입체 조형물을 제조할 수 있고, 보관 시 침전 안정성이 높을뿐만 아니라 3D 프린터 출력 과정 동안에도 그 점도를 유지할 수 있는 광경화성 3D 프린팅용 세라믹 슬러리의 제조방법 관한 것이다.

实时监测的上气道梗阻双区域耦合风险预警系统及方法

Resumen de: CN122681455A

本发明公开了实时监测的上气道梗阻双区域耦合风险预警系统及方法，涉及医疗监护技术领域。本发明采用颏下区柔性压电传感器阵列实时采集舌根、会厌及喉前庭组织振动信号，采用肋弓下柔性压电传感器阵列实时采集膈肌机械运动信号，经信号处理、特征提取后，由上气道振动异常指数与膈肌功能下降指数多模态耦合计算动态风险指数，并在超过阈值时输出分级预警信号。本发明实现了上气道通畅性与呼吸驱动功能的同步、无创、连续监测，可在血氧饱和度下降前提前识别梗阻前状态，具备无感佩戴、操作门槛低、针对高危人群精准预警等优点。

雾化器显示系统

Resumen de: US20260263707A1

0000 A nebulizer display system includes a display device and a nebulizer. The display device is configured to maintain an outputted visual record when not powered, and the display device includes an authentication code carrier. The nebulizer is configured to detect drug administration information related to a nebulized medicine sprayed by the nebulizer, and establish a connection with the authentication code carrier when sensing the authentication code carrier to transmit the drug administration information to the authentication code carrier. The authentication code carrier induces an induced current through an induction effect of the nebulizer to supply power to the display device. The display device updates the outputted visual record based on the drug administration information received by the authentication code carrier.

一种基于AI视觉的消毒剂有效浓度闭环质控方法及系统

Resumen de: CN122682062A

0001 本发明公开了一种基于AI视觉的消毒剂有效浓度闭环质控方法，具体涉及医疗器械消毒技术领域，包括以下步骤：消毒槽绑定与唯一标识建立；通过移动终端扫描消毒槽上的二维码，将该消毒槽与待测消毒剂的唯一ID进行电子绑定；系统自动生成包含消毒剂批次、生产日期、初始浓度及绑定时间的唯一标识编码，并记录操作人员身份信息与自动时间戳；同步在可视化仪表盘中实时展示绑定状态与多源数据聚合视图；本发明通过在消毒操作起始阶段强制执行消毒槽ID、消毒剂批号与系统授时时间戳的三元绑定，生成全局唯一的事件标识，并以此作为数据主键贯穿后续全部流程，消毒槽状态实时可视、多槽并发管理高效有序。

一种基于多模态生理信号的儿童情绪识别方法及系统

Resumen de: CN122681479A

0001 本发明公开了一种基于多模态生理信号的儿童情绪识别方法及系统，涉及生物医学信号处理、情感计算与智能玩具技术交叉领域，通过硬件时序对齐机制将光电容积脉搏波、皮肤电反应及体表温度信号对齐至统一时间轴，提取多维度情绪特征，在此基础上引入个体自校准机制，生成与当前儿童神经生理特性相匹配的个性化耦合特征提取函数，并结合耦合特征时序建模检测情绪唤醒事件。在个体自校准确保情绪状态稳定判别后，进一步构建闭环自适应刺激调节系统，根据识别到的情绪类别生成感觉刺激信号，实时提取生理响应特征并与期望生理响应模式比较，根据偏差动态调整刺激参数，形成感知‑调控闭环，将负向情绪向目标情绪状态引导。

一种全骨科的寒地手术机器人智能导航定位系统及方法

Resumen de: CN122681584A

0001 本申请提供了一种全骨科的寒地手术机器人智能导航定位系统及方法，所述系统包括：智能评估模块，用于生成辅助评估结果；关节置换规划与执行模块，用于进行针对性的手术规划、配准映射及控制机械臂执行该手术规划；脊柱手术规划与执行模块，用于进行针对性的手术规划、配准映射及控制机械臂执行该手术规划；创伤手术规划与执行模块，用于进行针对性的手术规划、配准映射及控制机械臂执行该手术规划；运动医学规划与执行模块，用于进行针对性的手术规划、配准映射及控制机械臂执行该手术规划；辅助康复模块，用于生成康复方案。这样，通过寒地手术机器人智能导航定位系统，可以针对不同的骨科疾病进行针对性的辅助评估、手术和辅助康复。

一种基于多模态指尖传感的神经功能评估系统及数据融合方法

Nº publicación: CN122681423A 04/09/2026

Solicitante:

广西桂林守月科技有限公司

Resumen de: CN122681423A

本发明公开了一种基于多模态指尖传感的神经功能评估系统及数据融合方法。系统集成于指套式可穿戴设备内，包括：至少三个精度为±0.1摄氏度的温度传感器，通过集成电路总线连接；一个六轴惯性测量单元，通过串行外设接口总线连接；一个可控振动输出模块，通过脉冲宽度调制控制线连接；以及一个主控制器。主控制器被配置为：根据六轴惯性测量单元数据监测运动状态并控制测试质量；根据多点温度数据构建温度补偿模型；执行心理物理阈值追踪算法定量评估振动感知阈值。本发明首次将主动振动刺激输出、高精度温度感知与六轴运动追踪融合于单一指套设备，可同时应用于化疗诱导周围神经病变评估、糖尿病周围神经病变评估、帕金森病监测及康复医学评估，实现标准化、定量化的神经功能评估。