Alerta

POROUS THREE-DIMENSIONAL MENISCUS SCAFFOLD AND BIODEGRADABLE MEDICAL DEVICE COMPRISING SAME

Resumen de: EP4803111A1

0001 The present invention relates to a porous three-dimensional meniscus scaffold and a biodegradable medical device comprising the same, and according to the present invention, an external force applied to the meniscus scaffold can be more stably and uniformly distributed by appropriately controlling a ratio of inter-fiber spacings within the meniscus scaffold, and as a result, a biodegradable medical device comprising the meniscus scaffold can exhibit improved structural stability.

WATER-SOLUBLE, BIOCOMPATIBLE, BIODEGRADABLE, 3D-PRINTABLE, AND RADIATION-CURABLE POLYMERIC PRODUCTS USED AS BIOINK

Resumen de: WO2025095908A1

This invention provides water-soluble, biocompatible, biodegradable, 3D-printable, and radiation-curable polymeric bioinks for tissue engineering and a variety of other biomedical applications. Synthesized using tailor-designed polyurethane and polyurea oligomers with controlled molecular weights and compositions, these bioinks offer optimized viscosity profiles for 3D printing and enhanced mechanical properties and structural stability. They are applicable in tissue engineering, wound healing, drug discovery, and other biomedical fields.

DEVICES AND METHODS FOR POSITIONING DENTAL AUXILIARIES ON TEETH

Resumen de: WO2025097054A1

Devices, methods, and systems for placing dental auxiliaries on teeth are provided. In some embodiments, for example, a dental auxiliary positioner for placing a dental auxiliary on a tooth includes: a registration element configured to receive a patient's tooth; and an auxiliary support coupled to the registration element and further coupled to an auxiliary, where the auxiliary support is configured to position the auxiliary against a surface of the tooth, and where the auxiliary support includes a frame extending at least partially around the auxiliary, one or more struts coupling the auxiliary to the frame, and a flexible bridge coupling the frame to the registration element, where the flexible bridge is configured to bend in one or more directions relative to the tooth to adjust the position of the auxiliary on the surface of the tooth.

METHODS AND PROGRAMS FOR PROVIDING PET HEALTH CARE SERVICES

Resumen de: KR20240027512A

A method for providing a companion animal health management service according to one embodiment of the present disclosure is disclosed. The method includes: a step of obtaining at least one of the contents of a companion animal medical consultation conducted at a veterinary hospital and general consultation contents received from a guardian through a companion animal health management service web link; a step of inputting at least one of the contents of the medical consultation composed of voice and the contents of the general consultation into a speech to text (STT) model to obtain text data; a step of performing natural language processing on the text data to generate a home care guide for the companion animal; and a step of outputting the home care guide through the companion animal health management service web link, wherein the companion animal health management service web link is accessible through a specific web page accessible from the guardian's terminal or a message transmitted to the guardian's terminal, and when the guardian visits the veterinary hospital, a message including an address of the web link can be transmitted to the guardian's terminal.

PRINTABLE DOSE FORMULATION

Resumen de: WO2025093812A1

The present disclosure concern printable dose formulations comprising an active pharmaceutical ingredient and excipients including one or more surfactants of hydrophilic-lipophilic balance (HLB) of at least 8. The disclosure also relates to a method for preparing medicament dosages using the printable dose formulations.

DISSOLVABLE PORE REINFORCEMENT FOR SURFACE OVERMOLDING

Resumen de: EP4803046A1

0001 A method of manufacturing an implant (200) including additively manufacturing the implant (200) from a first material such that the implant (200) defines a plurality of pores (205). Then inserting a filler material (206) into the pores (205) after the implant (200) has been manufactured. Next, overmolding the implant (200) with a second material after the filler material (206) has been inserted the pores (205), and then dissolving the filler material (206) from the pores (205) prior to deployment of the implant (200).

MAGNESIUM BASED CLEANING DEVICE

Resumen de: WO2025093736A1

This document relates to a cleaning device for curettage, such as removal of biofilm, inflamed granulation tissue and/or inflamed crevicular epithelium, of a surface, such as a bone, implant and/or tooth root surface. The cleaning device has cleaning means that comprises or consists of magnesium and/or a magnesium alloy which is hard enough to allow for curettage. Further, when the cleaning device is used, the magnesium and/or magnesium alloy detaches from the cleaning device and deposit on the cleaned surface thereby providing a positive biological effect in addition to the cleaning action, such as e.g. increased wound and/or bone healing, and/or reduced inflammation.

整形外科用プロテーゼの推奨のためのグラフ畳み込みネットワークモデル

Resumen de: AU2024332355A1

For each node of a plurality of nodes of a graph, a computing system generates a feature vector for the node that initially includes feature data characterizing one or more aspects of a bone of a patient. The graph includes one or more edges. Each of the edges connects a respective pair of the nodes. The computing system applies a graph convolutional network (GCN) model to the graph and the feature vectors for the nodes to generate output. The computing system determines, based on the output, one more recommended prostheses for the patient or recommended values of one or more prosthesis parameters.

Systems, apparatuses and methods for managing imaging of a patient

Resumen de: GB2704443A

The method comprises acquiring 102 radiotherapy treatment plan RTP information. The RTP is for delivering a radiation dose distribution to the patient so as to respect at least one radiotherapy treatment objective. The method further comprises determining 104 based on the acquired RTP information, a measure of sensitivity of the RTP to changes in anatomy of the patient. The measure of sensitivity is a function of position in the patient or a function of radiotherapy beam direction in the RTP. The method further comprises generating 106, based on the determined measure of sensitivity, an imaging protocol for obtaining a reconstructed CBCT image of a volume of the patient by setting a value of at least one parameter in the imaging protocol such that image quality of the reconstructed CBCT image of the patient volume meets an image quality objective for an image processing task. The image quality objective prioritises image quality for positions within the patient volume at which the RTP is sensitive to changes in anatomy. Fig 1

SYNTHETIC BASAL MEMBRANE AND METHOD FOR ITS MANUFACTURE

Resumen de: EP4803109A1

Die vorliegende Erfindung betrifft Verfahren zur Herstellung einer künstlichen Basalmembran umfassend ein Fasergelege, künstliche Basalmembranen, umfassend ein Fasergelege, insbesondere hergestellt mittels des erfindungsgemäßen Verfahrens sowie in vitro-Testsysteme, Zellkultursysteme, Filtrationssysteme und Organsysteme, umfassend mindestens eine künstliche Basalmembran der vorliegenden Erfindung.

CLICK EVENT IDENTIFICATION IN DELIVERY DEVICES

Resumen de: EP4804200A2

0001 The invention is concerned with a reliable manner of monitoring an injection process executed by means of a variable dose injection device with feedback means for generating a number of feedback events proportionate to the dose to be determined. A dialed or injected dose is determined by measuring a first signal of the process comprising a first signal peak related to a feedback event; detecting the first signal peak in the first signal; selecting an evaluation interval comprising the detected peak and adapted to an expected peak duration; deriving, from the first signal limited to the evaluation interval, a feature or characterizing parameter of the feedback event; identifying, from the derived feature, the feedback event as one of a dial up, dial down, or expel feedback event, and counting the number of identified feedback events to determine the dialed or the ejected dose. The two-stage approach with serially executed peak detection and peak identification separates an initial localization of a signal peak possibly related to a feedback event from a subsequent analysis of the detected signal peak in view of a possible source or origin feedback event, and allows to optimize data storage and processing power requirements.

CONTINUOUS ANALYTE MONITORING SYSTEM POWER CONSERVATION

Resumen de: EP4802999A2

0001 Disclosed are devices, systems and methods for power management in an electronics unit of a sensor device, e.g., such as in a continuous analyte sensor system. In some example embodiments, there is provided a method that includes monitoring, by a controller of a sensor electronics module, counts associated with signals received from a sensor device for a first period of time. The method also includes comparing a number of received counts with one or more benchmarked count thresholds, and determining whether to initiate an operational mode of the sensor electronics module based on the comparison. Related systems, methods, and articles of manufacture are also described.

개인용 약물 주입 시스템을 제공하는 방법

Resumen de: US12496392B1

A method of providing a personal drug injection system is disclosed. The method comprises determining at least one anthropometric characteristic from a person, and providing a plurality of types of personal drug injection systems. Each personal drug injection system of a personal drug injection system type is configured so as to fit with a part of the person's body that is intended to receive an injectable drug, and includes a drug injection location set that includes at least one defined drug injection location corresponding to a location of a drug injection site on the part of the person's body when the personal drug injection system is disposed on the part of the person's body. Each personal drug injection system type is associated with a defined range of anthropometric characteristics that is different to the defined range of anthropometric characteristics associated with the other personal drug injection system types, and each personal drug injection system type has an associated drug injection location set that is different to the drug injection location set of the other personal drug injection system types. The method also involves using the determined anthropometric characteristic and the defined ranges of anthropometric characteristics to select one of the personal drug injection system types from the plurality of personal drug injection system types already manufactured, and providing the person with the selected personal drug injection system type.

治療計画に個別化された歯科矯正アライナーセットのためのプロセスおよびシステム

Resumen de: EP4512363A1

0001 The present invention relates to a process for the production of an orthodontic aligner set comprising at least two aligners of different aligner shell materials, wherein the process at least comprises the production steps of: a) providing at least two different physical dental models, wherein the dental models comprise a base plate and a teeth configuration thereon, wherein the teeth configuration defines at least a part of a patients present or future teeth configuration and each model comprises an individual identifier, wherein the identifier comprises information at least encoding for the specific patient and the aligner shell material; b) placing at least one of the physical dental models provided in step a) in a deep draw chamber; c) Reading the individual identifier on the physical dental model and presenting at least the encoded information with respect to the aligner shell material, wherein the reading is performed after step a) and before step d); d) Selecting the specific aligner shell material as represented by the encoded information in process step c); e) Placing the selected aligner shell material over the physical dental model, heating of the aligner shell material, wherein the heating is performed prior, during or after placing of the selected aligner shell material, and deep drawing the aligner shell material to the physical dental model in order to produce a single orthodontic aligner; f) Removing the dental model and the orthodontic aligner from th

患者特有医療手順及びデバイス及び関連システム及び方法

Resumen de: AU2026205447A1

Systems and methods for designing and implementing patient-specific surgical procedures and/or medical devices are disclosed. In some embodiments, a method includes receiving a patient data set of a patient. The patient data set is compared to a plurality of reference patient data sets, wherein each of the plurality of reference patient data sets is associated with a corresponding reference patient. A subset of the plurality of reference patient data sets is selected based, at least partly, on similarity to the patient data set and treatment outcome of the corresponding reference patient. Based on the selected subset, at least one surgical procedure or medical device design for treating the patient is generated. ul u l

基于S4的HCM患者疗法调整

Resumen de: US20250261867A1

0000 Systems and methods are disclosed. A device may include a signal receiver circuit configured to receive physiologic information of a patient, including S4 heart sound information. A device may include an assessment circuit configured to: receive an indication of HCM for the patient, determine a change in an HCM condition using the received S4 heart sound information over a first time period, the first time period comprising multiple days, and provide an indication to a user or process based on the determined change in the HCM condition exceeding an alert threshold.

用于经日程安排的神经调制疗法的系统和方法

Resumen de: US20250249254A1

0000 Systems and methods for schedule neuromodulation therapy are disclosed. An exemplary system comprises an electrostimulator and a controller. The electrostimulator can be configured to provide electrostimulation to a neural target of a patient. The controller circuit can be operably connected to the electrostimulator. The controller circuit can be configured to determine an activity parameter based on a schedule parameter of the patient, wherein the schedule parameter is associated with a schedule of the patient; determine stimulation parameters based on the activity parameter; and deliver the electrostimulation to the neural target of the patient using the stimulation parameters.

多接收器环境中的警报优化

Resumen de: WO2025136999A1

In one embodiment, a method of alert optimization includes receiving, at a first device, one or more analyte measurements produced by an analyte sensor worn by a patient. The method also includes determining, at the first device, a first unique identifier for a first alert based on the one or more analyte measurements. The method also includes comparing, at the first device, the first unique identifier for the first alert to a stored record that includes unique identifiers for historical alerts. The method also includes conditionally suppressing the first alert on the first device based on the comparing.

一种基于肠-脑轴数字孪生的预测性灌肠控制方法及装置

Resumen de: CN122701960A

0001 本发明公开了一种基于肠‑脑轴数字孪生的预测性灌肠控制方法，包括：1、持续采集多模态数据并实时推理排便概率；2、执行“协同干预”策略时调用患者专属的数字孪生体；3、依据具体情况分为A和B两种子策略，子策略A优先进行低频神经调控预刺激，子策略B首先进行神经预激活，随即启动物理灌注，并实测压力，当达到终止条件时停止灌注；4、整合全流程数据操作记录，动态更新预测阈值，并异步触发模型重训练，同时修正数字孪生参数，强化学习优化神经刺激策略。本发明还公开了一种基于肠‑脑轴数字孪生的预测性灌肠控制装置。本发明最终达到了“提前干预、精准预演、神经重塑”的三重创新性效果，可以广泛应用于医疗器械与人工智能技术领域。

可用于确定患炎性肠病的个体的疾病位置的方法和试剂盒

Resumen de: US20260265841A1

0000 In some embodiments, provided is a method for identifying a stool sample with an altered microbiome associated with IBD with disease above TI comprising the steps of: a) determining the relative abundance of a set of bacterial species in the stool sample; b) comparing the relative abundance of each bacterial species in the set of bacterial species from the individual with the relative abundance of each bacterial species in the set of bacterial species in a reference data set to generate a risk score; and c) determining the stool sample as having an altered microbiome associated with IBD with disease above the TI if the risk score is higher than a cutoff value. Other embodiments are described herein. In some embodiments, provided methods, kits, products and uses of compositions provide a cost-effective, non-invasive method to support clinical decision making, and hence to help improve disease management regarding disease above TI.

一种失禁皮炎风险多模态传感预警系统

Resumen de: CN122701274A

本申请提供了一种失禁皮炎风险多模态传感预警系统，包括气体传感阵列、排泄物特征分类单元、多波长光学传感模块、风险融合评分单元和干预指令输出单元。所述气体传感阵列在控制器休眠期间持续监测排泄特征气体浓度，浓度越限时产生硬件中断唤醒控制器。所述排泄物特征分类单元读取多通道信号并通过归一化处理和模板匹配确定排泄物类型及置信度。所述多波长光学传感模块按需激活，基于不同波长反射信号比值获取红斑指数和血流灌注指数。所述风险融合评分单元将排泄物类型、皮肤指标和暴露时间通过加权融合模型计算风险得分并确定风险等级。所述系统以事件驱动架构实现极低功耗下的排泄物分类和皮炎风险量化预警。

一种基于VR的自闭症儿童感官脱敏训练方法

Resumen de: CN122702000A

本申请涉及虚拟现实技术领域，具体公开了一种基于VR的自闭症儿童感官脱敏训练方法，旨在解决传统物理环境中感官脱敏训练存在的安全隐患与刺激强度难以控制的问题。该方法通过构建多感官反馈的虚拟现实训练系统，采用头戴式显示设备和手持式交互控制器，基于具身认知理论设计视觉、听觉、触觉同步反馈机制，并建立感官刺激强度分级模型；实施沉浸式引导训练，通过虚拟场景中的引导信息和闭眼过渡动画营造安全氛围；实施触觉脱敏与视觉适应训练，通过可交互虚拟动物、触觉反馈、视觉特效和亲情角色激励完成感官脱敏；实施情绪整合训练，通过心形拼图重组和透明度渐变动画完成情绪调节；实时监测训练数据并动态调整训练方案，实现个性化方案的自动优化。本申请通过采用上述技术方案，能够实现为自闭症儿童提供安全可控的渐进式感官脱敏训练环境，有效融合具身认知理论，激发心流体验与情感支持，显著提升训练依从性和效果。

一种放射性粒子肿瘤内放疗智能高效布源规划方法

Resumen de: CN122715933A

本发明涉及一种放射性粒子肿瘤内放疗智能高效布源规划方法，方法包括以下步骤：步骤S1，对恶性肿瘤靶区进行分割重建，得到恶性肿瘤靶区几何模型；步骤S2，训练神经网络RDCN，得到轻量化RDCN毫秒级剂量计算模型；步骤S3，将几何模型的靶区及危及器官三维掩膜作为计算模型的输入，在剂量‑解剖双重约束下执行个体化全局布源迭代优化，得到最终个体化最优布源方案。与现有技术相比，本发明具有实现平衡优化精度与计算效率，实现个体化、高效率、剂量学更优的布源规划效果等优点。

人体气机监测系统

Resumen de: CN122701278A

一种基于人体气机监测系统，涉及医学领域，包括：接收模块，用于接收用户的气机数据；处理模块，用于对所述气机数据进行处理得到特征值；偏性量化模块，用于基于人体偏性量化模型将所述特征值转化为人体的六维偏性矢量BT_h；存储模块，用于存储中药药性标准数据库、经方锚定库，处理模块还用于将所述人体的六维偏性矢量BT_h与所述经方锚定库中的的标准证型进行比对，得到符合用户病机偏性的推荐方药方案；以及输出模块，用于输出所述推荐方药方案。本系统利用气机数据实现早发现、早干预、早治疗。

放射性微球剂量的计算方法、装置、电子设备及介质

Nº publicación: CN122702065A 08/09/2026

Solicitante:

清华大学

Resumen de: CN122702065A

0001 本申请公开了一种放射性微球剂量的计算方法、装置、电子设备及介质，涉及数据处理技术领域。通过多模态影像融合构建肝动脉模型，为剂量计算提供精确的几何基础；其次从二维肝动脉造影影像中提取血流信息计算血流动力学场，真实反映目标对象的血流状态；再利用血流场驱动模拟颗粒输运并与真实分布对比，迭代修正颗粒映射模型参数，消除造影剂与颗粒物理属性差异带来的预测偏差；将放射性微球物理属性映射至修正模型后，在个体化血流环境中模拟放射性微球的运动与沉积，最终生成体素级剂量分布图，实现从分区概算到体素级精准计算的提升，为治疗方案的精准制定提供可靠依据。