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105
resultados
Última actualización
30/06/2025 [07:19:00]
Resultados 100 a 105 de 105
Resumen de: US2025110128A1
A method for detecting biological objects by means of an SPR imaging detection system comprising an optical measurement device configured to generate plasmon resonance on a functionalized surface when said surface is exposed to a gas; the method comprising: an assimilation step by exposing the functionalized surface to a sample of interest formed of an aqueous carrier liquid containing the biological objects; a step of removing the liquid in contact with the functionalized surface and exposing the surface to a gas not containing the biological objects, said objects remaining bound to the ligands of the sensitive site of the functionalized surface; a step of acquiring an image of the sensitive site; a step of detecting the biological objects from the acquired image.
Resumen de: AU2023323947A1
The invention is directed to immunogenic compositions and method of treatment comprising a peptide or nucleic acid that encodes the peptide that induces an immune response in a mammal that is protective against infection by one or more pathogens. The peptide sequence contains multiple epitopes, wherein at least one epitope is a composite epitope which is a combination of two or more conserved epitopes of the pathogen wherein the amino acid sequence of the composite is not an amino acid sequence of the pathogen. In addition, the invention is directed to vaccines comprising the peptide or nucleic acid that encodes the peptide for treating and preventing an infection in mammals such as animals and humans.
Resumen de: CN119736221A
本发明公开了一种表达Bcf菌毛的重组菌株，重组菌株由将含有Bcf操纵子基因的表达载体导入惰性载体菌中得到。将Bcf操纵子基因插入到表达载体pBR322中得到重组质粒，将所述重组质粒导入惰性载体菌S9中得到所述重组菌株，惰性载体菌S9的保藏编号为CGMCC No.17340。上述重组菌株在快速、特异性、敏感性、稳定性、简单和价廉等方面表现更好，能够满足畜禽群的沙门氏菌感染现场和大规模、大批量、快速检测的要求，通过靶向检测多种血清型沙门氏菌感染，适用于沙门氏菌的大规模初筛工作。还能够对沙门氏菌疫苗接种后抗体水平进行监测。
Resumen de: CN119736297A
The invention relates to the technical field of biological medicine, in particular to an editing method of salmonella pullorum genome nucleotide and a composition and application thereof. The editing method comprises contacting a Salmonella pullorum genome with one or more guide RNAs and a binding protein comprising programmable DNA, wherein the guide RNAs target a base editor to effect alteration of genome nucleotides. A proper LbCpf1 variant is found through a nuclease mutation experiment when a specific site is targeted, the LbCpf1 variant is more suitable for targeting the specific site (such as a specific gene target of a PhnT gene), and compared with other gene editing proteins (such as other nuclease or LbCpf1 WT), the LbCpf1 variant has the advantage that the editing efficiency is remarkably improved.
Nº publicación: CN119736217A 01/04/2025
Solicitante:
COFCO NUTRITION AND HEALTH RES INSTITUTE CO LTD
COFCO CORP
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Resumen de: CN119736217A
The invention relates to the field of microorganisms, and discloses lactobacillus plantarum with an antibacterial effect and application of the lactobacillus plantarum, and the preservation number of the lactobacillus plantarum is CGMCC (China General Microbiological Culture Collection Center) No.33151. The strain provided by the invention has relatively strong cholate resistance, gastric acid resistance, acid production and H2O2 production capabilities, and has a relatively strong bacteriostatic effect on common pathogenic bacteria such as staphylococcus aureus, candida albicans, escherichia coli, salmonella and helicobacter pylori; the compound can inhibit the activity of urease, interfere helicobacter pylori colonization and the like to inhibit helicobacter pylori infection or reduce the symptoms of helicobacter pylori infection and reduce the disease degree of mice with colitis, can be used for preparing microbial preparations, and has the potential of preparing drugs for preventing and/or treating diseases caused by helicobacter pylori infection.
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