Resumen de: WO2025111571A1
An apparatus includes a 3D model of a soft tissue. The 3D model includes an anatomically correct outer wall defining an internal cavity. The 3D model further includes a reduced scale duplicate of the outer wall positioned with in the internal cavity. The reduced scale duplicate divides the internal cavity into an inner chamber within the reduced scale duplicate and an outer chamber between the reduced scale duplicate and the outer wall. The 3D model further includes ports extending from each of the inner chamber and the outer chamber to an exterior of the outer wall. Each port is configured to connect to a device that is configured to inject liquids into each of the inner chamber and the outer chamber.
Resumen de: WO2025110384A1
The present invention relates to a composite resin for esthetic restorations with improved antimicrobial properties and polymerization depth, and a manufacturing method therefor, wherein the compositive resin comprises urethane dimethacrylate (UDMA), bisphenol A-glycidyl methacrylate (BIS-GMA), bisphenol A dimethacrylate ethoxylated (BIS-EMA), triethylene glycol dimethacrylate (TEGDMA), a photoinitiator, a co-photoinitiator, a filler, barium glass, an accelerator, an antioxidant, a discoloration inhibitor, and an antimicrobial agent in addition to lysozyme. With the enhanced polymerization depth, the resin can be applied as a bulk-fill resin, and the excellent antimicrobial properties thereof provide resistance against bacteria and viruses. After polymerization, the resin exhibits a flexural strength exceeding 80 MPa, which is a level required by the Korean Ministry of Food and Drug Safety.
Resumen de: WO2025107170A1
Disclosed are a bio-ink for promoting microangiogenesis, a method for preparing same, and use thereof. The bio-ink is prepared by the following method: 1) preparing a filamentous microgel with a diameter within 20 microns from a sacrificial-phase material A as a porogenic template; 2) seeding vascular endothelial cells and perivascular cells on the surface of the filamentous microgel to give a hydrogel microfilament with the surface loaded with cells; and 3) mixing the hydrogel microfilament with the surface loaded with cells with a solution of a matrix-phase material B to give the bio-ink for promoting microangiogenesis. The bioprinting using the bio-ink can construct a capillary-like structure and cross-scale microvessels. The present invention can achieve the preparation of a micro-channel porous hydrogel structure with an average diameter of 20 microns or less and controllable porosity and the formation of a capillary-like network structure.
Resumen de: KR102815488B1
본 개시는 다이렉트 3D 프린팅용 광경화성 형상복원 고분자성 조성물 및 이를 이용하여 제조한 치아 교정장치에 관한 것으로, 보다 상세하게는 제1 온도범위에서 치아교정에 적합한 강성, 강직성, 및 탄성을 가지고, 상기 제1 온도범위와 상이한 제2 온도범위에서 원형복원 특성을 가지는 다이렉트 3D 프린팅용 광경화성 형상복원 고분자성 조성물 및 이를 이용하여 제조한 치아 교정장치에 관한 것이다.
Resumen de: KR20250000823U
하지 절단 환자의 환부와 의족 사이에 삽입되는 맞춤형 의족 보조기구가 제공된다. 적어도 일부가 상기 환부와 접촉하는 곡면을 포함하는 제1 면, 상기 제1 면으로부터 이격 형성되며, 적어도 일부가 의족과 접촉하는 곡면을 포함하는 제2 면, 및 상기 제1 면 및 상기 제2 면의 사이에 형성된 완충부를 포함하여, 착용시 환자의 환부에 가해지는 하중을 분산시킬 수 있다.
Resumen de: CN222917965U
本实用新型涉及一种负压微针给药装置,包括:壳体,壳体的顶部设置有注射器接口,注射器接口用于连接外部的注射器;壳体的底部设置有凹槽和凸起,凸起用于和皮肤贴合;壳体的内部设置有储药腔体和负压腔体,储药腔体和注射器接口连通;壳体的表面设置有负压接口,负压腔体的一端通过负压接口和外部的抽负压装置连接;凹槽的表面设置有通孔,负压腔体的另一端通过通孔和外部连通;微针,包括针头和中空的流道,流道设置在针头的内部,流道和储药腔体连通,针头凸出于凹槽的表面向外延伸,针头用于刺破皮肤。本实用新型可以有效地吸引皮肤靠近针头并自动刺破皮肤给药,提高了给药效果和患者的使用体验。
Resumen de: US2024131795A1
Systems, methods, and devices for computer-aided design, digital treatment planning, and direct additive manufacturing of dental appliances are provided. In some embodiments, a method includes receiving a treatment plan for a patient's teeth, the treatment plan specifying a target arrangement for the teeth and a plurality of treatment stages to reposition the teeth from an initial arrangement toward the target arrangement. The method can include identifying appliance design parameters for one or more dental appliances to implement at least one treatment stage of the plurality of treatment stages. The appliance design parameters can include one or more manufacturability parameters corresponding to an additive manufacturing process to be used to directly fabricate the one or more dental appliances. The method can further include determining an appliance geometry for the one or more dental appliances using the set of appliance design parameters.
Resumen de: CN120053115A
本申请公开一种高适配的根形种植体,涉及牙种植体技术领域,包括:根形种植体;根形种植体的外形完全贴合拔牙窝;根形种植体的顶部开设有向内的凹槽;凹槽用于固定中央螺栓和义齿种植基台;根形种植体是基于目标口腔CT数据,采用3D打印制作;目标口腔CT数据为拔牙窝处的CT数据;凹槽是基于义齿种植基台和中央螺栓的底部形态,采用机件加工在根形种植体上制备。本申请中根形种植体能够适配安装不同类型的中心螺栓和义齿种植基台,同时该根形种植体的应用也能有效地缩短牙种植手术的周期时间。
Resumen de: CN120053764A
本发明涉及软骨‑骨一体化类器官及其制备方法。所述软骨‑骨一体化类器官包括仿骨层与仿软骨层,所述仿骨层由基于压电水凝胶构建的仿骨基质力响应性生物墨水打印而成,所述仿软骨层由基于压电水凝胶构建的仿软骨基质力响应性生物墨水打印而成。本发明将压电材料与生物墨水相结合,利用3D生物打印技术精确构建软骨层和骨层的双生态位结构。通过压电材料将机械力转化为生物电信号,从而促进细胞活动和组织再生。同时,3D生物打印技术实现精确的结构控制,为关节软骨缺损修复提供了一种全新的策略。
Resumen de: CN120056233A
本发明涉及通过喷射打印生产牙科修复体的方法、装置和系统。本发明提供一种通过喷射打印来生产牙科修复体的方法,包括以下步骤:借助于陶瓷浆料喷射打印(S101)牙科修复体的一个或多个层;将着色溶液喷射打印(S102)至一个或多个层上;以及施加(S103)用于固定着色溶液的固定溶液。
Resumen de: CN120056234A
本发明涉及通过喷射打印生产牙科修复体的方法、装置和系统。本发明提供一种通过喷射打印来生产牙科修复体的方法,包括以下步骤:借助于陶瓷浆料喷射打印(S101)牙科修复体的一个或多个层;以及将半透明度增强剂和/或不透明度增强剂喷射打印(S102)至一个或多个层上。
Resumen de: CN120056232A
本发明涉及通过喷射打印生产牙科修复体的方法、装置和系统。本发明提供一种通过喷射打印生产牙科修复体的方法,包括以下步骤:使用具有彼此不同颜色的多种不透明陶瓷浆料来喷射打印(S101)牙科修复体的牙本质核;以及使用半透明陶瓷浆料来喷射打印(S102)牙科修复体的牙齿釉质。
Resumen de: CN120053748A
本发明公开一种骨修复支架及其制备方法与应用。所述骨修复支架由磷酸镁支架在钾盐溶液中养护而成,磷酸镁支架的原料包括磷酸三镁和打印墨水载体,磷酸三镁为三水磷酸氢镁和氢氧化镁,打印墨水载体由明胶溶液、甘油和戊二醛溶液制得。所述骨修复支架的制备方法包括:用三水磷酸氢镁和氢氧化镁制备磷酸三镁粉末;将明胶水溶液、甘油、戊二醛溶液混合均匀,得到打印墨水载体;将磷酸三镁粉末与打印墨水载体混合,并进行垂直沉积3D打印,得到磷酸镁支架;将磷酸镁支架置于磷酸氢二钾溶液中养护,得到磷酸镁骨修复支架。本发明提供的骨修复支架,能够达到力学强度高、孔隙率高的效果。
Resumen de: CN120055291A
本发明提供一种新型钛钽合金牙科种植体材料及其制备方法和应用,该制备方法包括以下步骤:S1.准备钛钽合金粉末,按质量百分比计包括以下元素成分:Ta:30‑50%、余量为Ti,待用;S2.建立牙科种植体三维模型,使用选择性激光熔化将S1所述钛钽合金粉末制备得到目标,所述3D打印激光功率为200‑350W,扫描速度为600‑800mm/s,层厚为20‑40μm,得到牙科种植体,待用;S3.对S2所得牙科种植体进行等离子体表面处理,功率为100‑300W,时间为10‑20min,即得所述新型钛钽合金牙科种植体材料。所得新型钛钽合金牙科种植体材料具有较低的弹性模量、优异的力学性能和生物相容性,能促进细胞增殖,显著改善了种植体的生物力学性能,兼顾耐用性和减轻应力屏障效应,特别适用于高要求临床场景。
Resumen de: US2025169939A1
The present invention is directed to providing a polymer scaffold for a prosthesis that may have a size and supporting force that may accurately correspond to a certain affected area, may also contain a maximum amount of a therapeutic drug, may be immediately applied in a customized manner to an affected area that has not been prepared in advance, and may provide a stable supporting force of the affected area throughout the treatment period, and a method of manufacturing the same. The polymer scaffold for a prosthesis according to the present invention and the method of manufacturing the same have an effect of allowing the internal rigidity and elasticity to be adjusted so that they can be provided in a customized manner to patients.
Resumen de: US2025171733A1
A bioink is described. The bioink comprises coral particles and biocompatible polymer, wherein the concentration of coral particles in the bioink is 25 to 85 weight % of the total weight of the bioink.
Resumen de: US2025170648A1
A method of producing a dental restoration (100) by jet printing, including the steps of jet printing (S101) one or more layers of the dental restoration using a ceramic slurry; and jet printing (S102) a coloring solution onto the one or more layers.
Resumen de: US2025169924A1
The present invention pertains to a transparent orthodontic device and a method for its preparation. The transparent orthodontic device described herein includes a tooth-contacting portion. This tooth-contacting portion consists of a concave section that makes contact with the tooth and a convex section that does not make contact with the tooth, positioned opposite each other.
Resumen de: US2025170353A1
A face mask assembly may include an oral appliance connected to a post. A face mask assembly may include a face mask comprising a shell, a liner, an adapter, and a threaded, slotted sleeve configured to receive the post. A face mask assembly may include a threaded nut configured to selectively engage the threaded, slotted sleeve, wherein engaging the threaded nut on the threaded, slotted sleeve causes the threaded, slotted sleeve to engage the post and fix the position of the face mask relative to the oral appliance.
Resumen de: US2025169929A1
A method of producing a dental restoration by jet-printing, including jet-printing one or more layers of a dental restoration using a ceramic slurry, jet-printing a coloring solution onto the one or more layers, and applying a fixing solution for fixing the coloring solution.
Resumen de: US2025169925A1
A system for correcting malocclusions may include a maxillary appliance having tooth receiving cavities shaped to receive teeth of a maxilla and a first elastic coupling at gingival line of the maxillary appliance. The first elastic coupling may be configured for receiving an elastic. The system may also include mandibular appliance having tooth receiving cavities shaped to receive teeth of a mandible. The system may also include a corrective appliance having a first coupling configured to be coupled to the mandibular appliance at a first location on a first side of incisors of a patient and a second coupling configured to be coupled to the mandibular appliance on a second side of the incisors, and having an arm extending from the corrective appliance towards the gingival line of the maxillary appliance and being shaped to receive the elastic.
Resumen de: US2025169892A1
Systems and methods for generating patient-specific surgical guides comprising: capturing a first and second images of an orthopedic element in different reference frames using a radiographic imaging technique, detecting spatial data defining anatomical landmarks on or in the orthopedic element using a neural network, applying a mask to the orthopedic element defined by an anatomical landmark, projecting the spatial data from the first image and the second image to define volume data, applying the neural network to the volume data to generate a reconstructed three-dimensional (“3D”) model of the orthopedic element; and calculating dimensions for a patient-specific surgical guide configured to abut the orthopedic element.
Resumen de: US2025171188A1
A method (600) for packaging a food product is provided. The method can comprise receiving (602) at least one piece of packaging material (PM) in a packaging machine (500), said packaging material (PM) comprising a cellulose-based mid-layer (400), an inside layer (404) arranged to face the food product (FP), and an outside layer (402), wherein an ink-based print is provided on the outside layer (402), curing (604) the inside layer (404) of the at least one piece of packaging material (PM) such that ink particles (302), released from the outside layer (402) to the inside layer (404), are bound to the inside layer (404), thereby preventing the ink particles (302) from being released into the food product (FP), forming (606) the at least one piece of packaging material (PM) into packages (110), and filling (608) the packages (110) with the food product (FP).
Resumen de: US2025169792A1
The present invention related to an ultrasound imaging system win which the scan head includes a beamformer circuit that performs far field subarray beamforming or includes a sparse array selecting circuit that actuates selected elements. When using a hierarchical two-stage or three-stage beamforming system, three dimensional ultrasound images can be generated in real-time. The invention further relates to flexible printed circuit boarde in the probe head. The invention furthermore related to the use of coded or spread spectrum signaling in ultrasound imagining systems. Matched filters based on pulse compression using Golay code pairs improve the signal-to-noise ratio thus enabling third harmonic imaging with suppressed sidelobes. The system is suitable for 3D full volume cardiac imaging.
Nº publicación: US2025172541A1 29/05/2025
Solicitante:
TEXAS TECH UNIV SYSTEM [US]
Texas Tech University System
Resumen de: US2025172541A1
Embodiments pertain to a bioink operational to form an artificial bone. The bioink includes a plurality of bone-related cells. Additional embodiments pertain to an artificial bone that includes a plurality of bone-related cells; and a bioink of the present disclosure that is embedded with the cells. The artificial bone may be in the form of a three-dimensional structure that includes a plurality of channels operational to allow fluid flow through the artificial bone. Further embodiments pertain to methods of making an artificial bone by applying a plurality of bone-related cells and a bioink onto a surface such that the bioink becomes embedded with the cells and forms a three-dimensional structure with a plurality of channels.