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一种3D打印骨小梁口腔种植体的方法

Resumen de: CN115740495A

The invention relates to a method for 3D printing of a bone trabecula oral implant. The bone trabecula oral implant comprises an implant base body and a bone trabecula porous structure which are integrally formed. The bone trabecula porous structure is positioned in the axial middle section of the implant base body; and the implant base body is provided with an external thread. The printing method comprises the following steps: obtaining an oral implant 3D model with a bone trabecula porous structure through three-dimensional design software; carrying out molding manufacturing, sand blasting and annealing treatment by utilizing an SLM technology to obtain a bone trabecula oral implant primary product; and forming a tantalum metal coating on the surface of the primary product of the bone trabecula oral implant by using a vapor deposition technology to obtain the bone trabecula oral implant with the tantalum coating. The bone trabecula oral implant obtained by the method is high in density and mechanical strength, favorable for the implant to exert a good repairing effect, and excellent in application prospect.

用于基于光的生物打印应用的生物墨水水溶液以及使用该生物墨水水溶液的方法

Resumen de: WO2024084040A1

The disclosure relates to an aqueous bioink solution for use in light-based bioprinting applications, comprising: (a) 0.5-95 wt % water-soluble prepolymer; (b) 0.001-5 wt % biocompatible metal acylphosphinate photoinitiator; (c) 0.001-10 wt % biocompatible light absorber; and (d) 5 to 99.5 wt % solvent. The disclosure further relates to a method of using the aqueous bioink solution including living cells and a method of using the aqueous bioink solution without living cells (acellularly).

一种防移位自适应自锁式人体管腔支架与制作方法

Resumen de: CN120078562A

本发明涉及一种防移位自适应自锁式人体管腔支架与制作方法，属于医疗器械领域。本发明包括支架单元和连接单元，相邻支架单元通过连接单元连接，其结构特点在于：所述支架单元包括呈菱形结构设置的主体框架、以及设置在主体框架内部的连接横梁、过渡横梁和榫卯横梁，所述连接横梁、过渡横梁和榫卯横梁依次连接，所述连接横梁和榫卯横梁均与主体框架连接，两个榫卯横梁上均设置有多个榫头，相邻榫头之间形成榫槽，其中一个榫卯横梁上的榫头与另一个榫卯横梁上的榫槽连接，其中榫头的数量不少于3个，榫槽的数量不少于2个。

促进骨质疏松性骨缺损修复的人工骨及其制备方法

Resumen de: CN120078956A

促进骨质疏松性骨缺损修复的人工骨及其制备方法，属于生物医学材料技术领域。本发明的人工骨由89.65wt%‑89.85wt%的聚乳酸‑羟基乙酸共聚物、9.85wt%‑10.15wt%的纳米羟基磷灰石以及0.1wt%‑0.5wt%的唑来膦酸复合而成。该人工骨中，纳米羟基磷灰石和唑来膦酸在聚乳酸‑羟基乙酸共聚物中均匀分散，结合人工骨表面的多孔结构，有利于成骨细胞在表面的附着，有利于新生骨组织的长入；唑来膦酸的膦酸根能够与纳米羟基磷灰石螯合生成稳定的化学键，将其引入到聚乳酸‑羟基乙酸共聚物中，可以实现唑来膦酸的有效负载，唑来膦酸的有效负载能够抑制破骨细胞过度活化导致的骨吸收增多，修复骨质疏松性骨缺损。

基于数字化可视化颌位重建技术的矫治器制作方法

Resumen de: CN120078532A

本发明涉及骨性Ⅲ类上颌发育不足的矫治器技术领域，尤其涉及一种基于数字化可视化颌位重建技术的矫治器制作方法，所述矫治器包括基底和颌垫，矫治器的制作包括以下步骤：S1：获取患者相关数据及第一次口扫数据，确定矫治器方案；S2：获取患者的静态咬合状态，确定初步的咬合目标位置，并获得第二次口扫数据；S3：将所述第一次口扫数据和所述第二次口扫数据分别导入至设计软件中，生成数字化模型；S4：通过数字化颌架确定最终颌位；S5：设计基底模型，并3D打印；S6：设计颌垫模型，并3D打印；本方法制作的矫治器组织面能完美匹配患者的牙齿外形，咬合记录目标位置更加符合人体生物学基础，设计更为精确，并可有效防止矫治器脱落。

一种可拆卸3D打印义齿的个性化适配卡扣

Resumen de: CN222929860U

本实用新型公开了一种可拆卸3D打印义齿的个性化适配卡扣，包括固定在义齿本体两侧的用于与相邻牙齿卡设安装的卡环，还包括设置在义齿本体上的用于义齿本体安装过程中与相邻牙齿之间适配挤压的适配挤压组件。本实用新型的一种可拆卸3D打印义齿的个性化适配卡扣，义齿在安装的过程中，通过传动，使两组挤压板的一端分别与义齿本体两侧相邻的牙齿相抵，通过相抵作用，对安装后的义齿本体进行自动的适配挤压，且在挤压适配的过程中，推动弹簧的弹力作用，使两组挤压板保持与相邻两组牙齿相抵，避免因使用者口腔的变化造成安装后义齿本体与相邻的牙齿之间产生间隙，便于义齿本体以更加稳定的卡扣方式安装固定。

ADDITIVE MANUFACTURING OF RADIOLOGICAL PHANTOMS

Resumen de: US2025152121A1

A formulation usable as a modeling material formulation in additive manufacturing of a three-dimensional object and additive manufacturing methods utilizing same are provided. The formulation comprises one or more curable materials; and a radiopaque material, and features, when hardened, a CT number of at least 100 HU at 70 kV. Objects made by the additive manufacturing method utilizing the formulation are usable as radiological phantoms.

一种3D打印生物墨水、矿化支架及制备方法和在矿化组织分级再生中的应用

Resumen de: CN120078947A

本发明提供了一种3D打印生物墨水、矿化支架及制备方法和在矿化组织分级再生中的应用，属于骨组织工程材料技术领域。本发明首先制备具有仿生形状和多孔网络的有机质微囊，通过引入多酚成核位点，矿化沉积迅速在微囊中发生，形成骨样羟基磷灰石纳米片聚集体，然后将其作为生物墨水的主要功能性单元，微囊经有机质连续相稳定组装，实现了植入体中矿化成核位点数量和生长域的个性化精准可控。通过3D打印制备矿化支架，本发明提供的矿化支架，在微囊内可形成丰富均质的矿化生长域，可有效促进间骨髓充质干细胞长入并形成矿化结节成为人工骨化中心，加快新生组织原位矿化和骨再生进程。

一种牙齿修复装置

Resumen de: CN120078618A

本发明公开一种牙齿修复装置，涉及医疗器械技术领域，包括支撑板，支撑板顶面固定安装有操作台，操作台上设有用于设置参数的触摸显示屏，操作台内安装有3D打印机，操作台上开设有第二凹槽，第二凹槽内放置有扫描仪，扫描仪用于对患者口腔进行非接触式扫描，操作台远离扫描仪的一侧开设有第一凹槽，第一凹槽内放置有安装笔，安装笔用于将修复体装入需要修复的牙齿内，操作台上开设有盛放槽，盛放槽用于放置修复体。本发明能够一次性完成从扫描到安装的全过程，显著缩短治疗周期，提高效率；减少就诊次数和手术创伤，提升患者治疗体验，增强舒适度；通过安装笔对修复体进行固定安装，保证与牙齿良好的贴合度。

一种光敏树脂组合物、树脂牙及树脂牙的制备方法

Resumen de: CN120081983A

本发明提供了一种光敏树脂组合物、树脂牙及树脂牙的制备方法。所述光敏树脂组合物包括如下质量百分比的组分：聚氨酯(甲基)丙烯酸酯类低聚物20～45％、单官能(甲基)丙烯酸酯单体5％～15％、多官能(甲基)丙烯酸酯单体10～30％、填料15～55％、引发剂1％～5％、紫外线吸收剂0.02％～0.12％和光稳定剂0.1％～0.3％。所述树脂牙由所述光敏树脂组合物通过光固化3D打印制备得到。采用本发明提供的光敏树脂组合物制备的树脂牙具有在口腔环境下力学性能稳定，在咀嚼循环条件下的耐疲劳性能良好的优点。

SYSTEM AND METHOD FOR PRODUCING PHARMACEUTICAL OBJECTS VIA 3D PRINTING

Resumen de: EP4523890A2

The invention relates to a system for producing pharmaceutical objects, such as tablets, granules and capsules, via 3D printing. The system comprises a 3D printing machine (2) with a mechanical system (3) movable in one or more directions, at least one print head (5) with at least one nozzle (37) being movable by the mechanical system (3) and a base system (4) carrying a print base (6) for receiving a prepared mixture (27) applied by the print head (5) and comprising formatted print locations (49) on the base (6) for shaping the pharmaceutical object. The formatted print locations (49) can be adapted to receive a blister such that the pharmaceutical objects can be printed directly inside the blister. The system can further comprise a closing device for applying a sealing membrane or film to hermetically seal the blister after the printing is completed. The invention further relates to a method for producing pharmaceutical objects with the system.

PEEK/ 3D .

Resumen de: KR20250077930A

기존의 임플란트는 대량생산하여 표면에 생체적합성 처리를 한 후 사용하였다. 그러나, 환자의 환부의 크기와 정도에 차이가 있기 때문에 환자맞춤형 임플란트가 더욱 선호되고 있다. 이를 위하여 환자에 따라 맞춤형으로 임플란트를 제작하고 사용하기 위하여 3D 프린팅 기술을 사용하고 있다. 그러나, 3D 프린팅된 임플란트를 다시 표면 처리하는 것은 비용도 많이들 뿐만 아니라, 까다로운 공정이 필요하기 때문에 어려움이 있다. 본 출원 발명은 생체 적함성 성분을 포함하는 3D 프린팅 소재를 제공함으로써 환자 맞춤형 임플란트를 프린팅하여 바로 사용할 수 있는 기술을 제공하고자 한다. 이를 이위하여 폴리에테르에테르케톤(PEEK)에 조개껍질 분말을 혼합하여 상기 임플란트를 3D 프린팅하는 방법을 제공하는 것을 특징으로 하는 3D 프린팅 기술에 의하여 생체적합성이 높은 임플란트를 제작하는 방법을 제공한다. 본 출원 발명의 상기와 같은 발명의 구성에 의하여 생체 적합성이 높고 알레르기 발생이 적은 임플란트 소재를 제공함으로써 3D 프린팅 기술을 사용하여 환자 맞춤형 임플란트를 제공할 수 있는 효과가 있는 발명이다.

TRANSPARENT, FRACTURE-RESISTANT POLYMERISATION RESINS FOR THE PRODUCTION OF DENTAL MOULDINGS

Resumen de: US2022370300A1

Radically polymerizable dental material, which contains at least one ABA or AB block copolymer, preferably at least one monofunctional, radically polymerizable monomer (a) and preferably at least one radically polymerizable urethane di(meth)acrylate telechel (b).

3D Antibacterial and antiviral 3D printing denture resin and manufacturing method thereof

Resumen de: KR20250078061A

본 발명은, UDMA(urethane dimethacrylate), BIS-GMA(bisphenol A-glycidyl methacrylate), BIS-EMA(ethoxylated bisphenol A dimethacrylate), TEGDMA(triethylene glycol dimethacrylate), 광개시제, 광개시보조제, 충전제, 촉진제, 산화방지제, 변색방지제 및 항균제를 포함하는, 항균 및 항바이러스성 3D 프린팅 의치상용 레진 조성물 및 이의 제조방법에 관한 것으로, 3D 프린팅에 적용되어 의치상용으로 사용되는 레진의 굴곡강도인 65MPa 이상을 달성하면서 동시에 항균 및 항바이러스 성능을 발현할 수 있다.

Impact resistant material

Resumen de: AU2025202262A1

The current disclosure is directed to an impact resistant material made from a novel melanin composite. It has been found that using these composites allows for the production of effective ballistic protection and blast containment materials.

Spherical tantalum powder, products containing the same, and methods of making the same

Resumen de: JP2024045166A

To provide a method for forming articles by additive manufacturing using tantalum powder.SOLUTION: There is provided a method for forming an article, wherein the method comprises a step of additive manufacturing to form the article by utilizing the tantalum powder to form the shape of the article or part thereof, and wherein the tantalum powder has following characteristics: a. spherical shape with an average aspect ratio of from 1.0 to 1.25; b. a purity of tantalum of at least 99.99 wt.% Ta based on total weight of the tantalum powder, excluding gas impurities; c. an average particle size of from about 0.5 micron to about 250 microns; d. an apparent density of from about 4 g/cc to about 12.3 g/cc; e. a true density of from 16 g/cc to 16.6 g/cc; and f. a Hall flow rate of 20 seconds or less.SELECTED DRAWING: Figure I

基于3D打印的复合人工骨及其制备方法

Resumen de: CN120053753A

本发明公开了一种基于3D打印的复合人工骨及其制备方法。复合人工骨的制备方法包括步骤：(1)将聚己内酯和磷酸钙混合并制为丝材；(2)按照预设模型，使用所述丝材打印成型得到3D打印多孔支架，所述多孔支架具有孔道结构；(3)将填充浆料注入所述多孔支架的孔道结构中，所述填充浆料含有胶原蛋白和磷酸钙，干燥，获得成型的复合人工骨；(4)将复合人工骨和交联剂进行化学交联，交联后清洗，干燥，获得复合人工骨产品。该复合人工骨具有较优的力学强度，可以有效促进大段骨缺损、骨不连治疗过程中的早期血管及新骨生长。

通过喷射打印生产牙科修复体的方法、装置和系统

Resumen de: CN120056235A

本发明涉及通过喷射打印生产牙科修复体的方法、装置和系统。本发明提供一种通过喷射打印来生产牙科修复体100的方法，包括以下步骤：借助于陶瓷浆料喷射打印(S101)牙科修复体的一个或多个层；以及将着色溶液喷射打印(S102)至一个或多个层上。

一种精确压低前牙的正畸矫治器的制作方法及正畸矫治器

Resumen de: CN120056314A

本申请涉及一种精确压低前牙的正畸矫治器的制作方法及正畸矫治器，精确压低前牙的正畸矫治器的制作方法包括根据数字化牙颌模型至少确定覆颌数值、覆盖数值和咬合平面，以及根据覆颌数值确定的需求压低量；确定预设覆盖阈值，根据预设覆盖阈值和覆盖数值之间的第一对比结果，确定对应的压低平台类型；确定预设压低量，根据预设压低量和需求压低量的第二对比结果，确定是否执行分阶段压低操作，若执行分阶段压低操作，则确定分阶段压低操作中的每个阶段压低量，分阶段压低量能基于用户交互窗口进行动态调整。不仅可以针对不同覆颌程度的患者提供个性化的矫治方案，还能确保压低量的精确控制，从而避免传统方法中因压低不准导致的反复调整问题。

一种仿生型种植桥架

Resumen de: CN120053114A

本申请公开了一种仿生型种植桥架，属于种植桥架领域。仿生型种植桥架包括种植体和连接体；种植体包括多个，每个种植体适配一个人体常规牙齿形状；多个种植体按人体常规牙齿顺序排列，相邻两个种植体之间通过连接体连接；每个种植体从牙尖至牙根的方向由实体结构向第一多孔结构变化以使弹性模量降低；每个种植体从牙齿中心至边沿的方向通过增加孔隙率使弹性模量降低；通过降低孔隙率使作为切牙、尖牙和磨牙的种植体的牙本质的弹性模量依次增加。本申请在采用同一种材料制作仿生型种植桥架的同时，实现根据人体生理牙齿不同位置具有不同的弹性模量，与人体生理牙齿实际弹性变形情况一致化，具有仿生学设计。

一种骨修复用3D打印聚乳酸复合支架及其制备方法

Resumen de: CN120053751A

本发明属于生物材料技术领域，具体涉及一种骨修复用3D打印聚乳酸复合支架及其制备方法。其中，骨修复用3D打印聚乳酸复合支架由以下原料制备而成：PLA/Mg‑ZrO2和BP/STAC；本发明采用PLA/Mg‑ZrO2作为3D打印支架，在PLA/Mg‑ZrO2支架表面形成BP/STAC复合涂层，制备得到骨修复用3D打印聚乳酸复合支架，PLA/Mg‑ZrO2支架具有模仿天然骨骼的分级孔隙率，PLA具有良好的生物相容性，Mg‑ZrO2的加入增强了PLA支架的力学强度和韧性，BP/STAC的复合涂层进一步增强了复合支架的力学性能，且有助于细胞附着和生长，加速了骨细胞的增殖和分化，促进新骨的形成。

MODELEUR MAXILLAIRE

Resumen de: WO2024033402A1

The invention relates to a maxillary modeller (2) intended to be worn, in a service position, on a dental arch of a user in order to modify the shape of the palate, the maxillary modeller being one-piece and removable and comprising: - a central palatal portion (22) configured to be in contact with the user's palate when the maxillary modeller is in the service position; and - a first and a second dental portion (24; 26) each comprising at least one, preferably multiple cavities configured to receive teeth of the user when the maxillary modeller is in the service position, the first and second dental portions extending on either side of the central palatal portion, the central palatal portion being configured so as to exert on the palate, in the service position, forces suitable for modifying the shape thereof.

バイオプリント線維構造を製造するためのシステム及び方法

Resumen de: AU2023271390A1

Aspects of the disclosure include a fabrication platform for supporting a bioprinted fiber structures during printing, patterning, and/or processing, comprising a frame with a plurality of posts for securing a cross-linkable fiber during printing thereof, and where a continuous length of the cross-linkable fiber is printed around a plurality of posts during the 3D bioprinting process. The fabrication platform enables the cross-linkable fiber to be suspended during one or more of printing, patterning, and/or processing. In this way, the bioprinted fiber structure comprises a uniform outer surface, and can be easily modified and/or further processed after printing and patterning are completed.

薬物溶出外科用物品およびその使用方法

Resumen de: CN119546355A

A biological material comprising a first porous polymer, a second non-porous polymer, and a therapeutic agent, and a method of using the same for treating a condition are disclosed. The biomaterials disclosed herein may be, for example, surgical articles. Implanting the biomaterials disclosed herein in a subject can treat, for example, cancer.

CONTRAST MARKERS FOR USE IN MEDICAL PROCEDURES

Nº publicación: WO2025111433A1 30/05/2025

Solicitante:

WAKE FOREST UNIV HEALTH SCIENCES [US]
WAKE FOREST UNIVERSITY HEALTH SCIENCES