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一种功能化骨软骨修复材料及其制备方法

Resumen de: CN121648349A

本发明公开了一种功能化骨软骨修复材料，包括依次连接的软骨层、过渡层和骨层，所述软骨层以透明质酸、I型胶原蛋白和壳聚糖为基材，所述过渡层以羟基磷灰石和聚乳酸‑羟基乙酸共聚物为基材，所述骨层以β‑磷酸三钙、羟基磷灰石和聚乳酸‑羟基乙酸共聚物为基材，本发明涉及医用生物材料技术领域，通过设计有机‑无机复合过渡层，梯度衔接软骨层和骨层，界面剪切强度≥0.5MPa，有效解决了传统分层材料层间剥离的问题，能承受关节运动时的剪切应力和压缩应力，制备工艺采用冷冻干燥、模压成型、烧结等成熟医用材料生产设备，可实现规模化批量生产，同时支持选择性激光烧结3D打印的个性化制备，适配不同临床场景需求。

用于通过3D喷墨打印制备由氧化锆制成的陶瓷成形体的方法和料浆

Resumen de: US2025018599A1

Process and slip for the production of ceramic shaped parts made of zirconium oxide ceramic by a 3D inkjet printing process. The slip contains zirconium oxide which is suspended in a liquid medium, wherein the slip has a zirconium oxide content of from 68 to 88 wt.-% and contains not more than 5 wt.-% organic components. The process for the production of ceramic components comprises the layered shaping and subsequent sintering of the desired component from the slip.

儿童咬合垫、基于适应性咬合的儿童咬合矫治系统及其设计方法

Resumen de: CN121647835A

本发明公开了儿童咬合垫、基于适应性咬合的儿童咬合矫治系统及其设计方法，儿童咬合垫包括两个本体，两个本体被配置为覆盖佩戴者上颌/下颌左侧后牙区和右侧后牙区，两个本体之间通过连接部连接；本体包括朝向对颌牙列的咬合面、以及朝向其所覆盖牙列的组织面；组织面形成有用于容纳目标牙齿的萌出窝；萌出窝由侧壁和与目标牙齿咬合面相适配的窝底壁限定而成，侧壁围绕一引导轴线延伸；其中，本体被配置为在佩戴状态下，引导轴线相对于佩戴者的腭平面垂线具有预设偏转角度，以通过引导轴线的方向引导目标牙齿的萌出；萌出窝的窝底壁具有沿引导轴线方向测量的预设厚度。本发明提供的儿童咬合矫治系统既能提高固位力，又能根据错��类型主动引导牙齿定向萌出、重塑功能咬合平面，从而通过消除下颌内旋/外旋机制来矫治颌骨畸形。

用于经由3D打印生产药物对象的系统和方法

Resumen de: AU2025205378A1

21894047_1 (GHMatters) P119307.AU.2 The invention relates to a system for producing pharmaceutical objects, such as tablets, granules and capsules, via 3D print- ing. The system comprises a 3D printing machine (2) with a me-5 chanical system (3) movable in one or more directions, at least one print head (5) with a nozzle (37) being movable by the me- chanical system (3) and a base system (4) carrying a print base (6) for receiving a prepared mixture (27) applied by the print head (5). The system comprises at least one carrier (35) for 10 holding a cartridge (28).Printing can be done on formatted print locations (49) on the base (6). The invention further relates to a method for producing pharmaceutical objects, comprising the steps of providing at least one pharmaceutical substance in at least one cartridge, placing the cartridge in a carrier, estab-15 lishing a fluid connection between a cartridge and a print head, such that the pharmaceutical substance may leave the print head through the print head nozzle, moving the print head nozzle ac- cording to a 3D print program and dispensing the pharmaceutical substance to a print base. 20 (Fig. 24) The invention relates to a system for producing pharmaceutical objects, such as tablets, granules and capsules, via 3D print- 5 ing. The system comprises a 3D printing machine (2) with a me- chanical system (3) movable in one or more directions, at least one print head (5) with a nozzle (37) being movable by the me- chanical system (3)

一种3D打印掺镁矿化胶原复合骨支架及其制备方法

Resumen de: CN121648350A

本发明化学技术领域，具体涉及一种3D打印掺镁矿化胶原复合骨支架及其制备方法，复合骨支架主要由掺镁矿化胶原、羟基磷灰石和左旋聚乳酸制成，左旋聚乳酸、镁矿化胶原和羟基磷灰石质量比为3~5∶2~4∶1。制备方法，其步骤为：胶原蛋白溶解在酸性缓冲溶液中，滴加含PO43‑溶液后，再依次滴加含Ca2+与Mg2+的混合盐溶液，制得混合溶液；S13在混合溶液中加入碱溶液调节混合溶液pH至8.0~9.0，生成掺镁矿化胶原；将掺镁矿化胶原、左旋聚乳酸和羟基磷灰石混合后通过3D打印制成复合骨支架。本发明的制备方法，克服胶原不稳定的技术偏见，可以实现一步共沉淀法钙镁磷共沉积。

壳状牙科器械制作方法

Resumen de: WO2021147336A1

A method for fabricating a shell-shaped dental instrument, comprising: obtaining a three-dimensional digital model of a shell-shaped dental instrument (101); inspecting the three-dimensional digital model of the shell-shaped dental instrument (103); according to the result of inspection, directly modifying the three-dimensional digital model of the shell-shaped dental instrument (105); and using 3D printing technology to make the shell-shaped dental instrument on the basis of the modified three-dimensional digital model of the shell-shaped dental instrument (107). The present method can overcome the limitations on various aspects of a shell-shaped dental instrument caused by the limitedness of the traditional hot pressing film forming process.

一种用于深部脑神经定向再生的微型蠕动器及其制备方法

Resumen de: CN121647847A

本发明涉及蠕动器技术领域，且公开了一种用于深部脑神经定向再生的微型蠕动器，包括微型蠕动器，所述微型蠕动器的表面设置有褶皱结构，所述微型蠕动器的内部设置有驱动结构，所述驱动结构为记忆合金丝，通过电流控制记忆合金丝，实现收缩与断电恢复形变，进而驱动微型蠕动器产生蠕动运动。本发明中，微型蠕动器整体呈蠕虫状且由两个C形结构组成，配合表面连续环状褶皱结构，可模拟自然界生物在狭窄空间的高效蠕动模式，既能适配深部脑神经区域复杂的管腔与组织间隙，又能避免蠕动过程中对周围软组织的刮擦损伤，同时褶皱结构为运动提供稳定波形动力，确保在精细神经环境中灵活前行。

Tibia-Implantat

Resumen de: DE102024126035A1

Die Erfindung betrifft ein Tibia-Implantat (2) für Gelenkersatz, welches aus Metalllegierung in einem additiven Fertigungsverfahrenhergestellt ist, mit einem Plateauabschnitt (4) und mit einem auf der tibiazugewandten Seite (8) des Plateauabschnitts (4) vorspringenden und sich davon in einer axialen Richtung (10) wegerstreckenden zapfen- oder kielförmigen Ankerabschnitt (6),; erfindungsgemäß wird vorgeschlagen, dass der Plateauabschnitt (4) auf seiner tibiazugewandten und mit Tibiaknochengewebe in Kontakt gelangenden Seite (8) eine dreidimensional poröse offenporige Oberflächenstruktur (14) mit in der axialen Richtung (10) hintergreifbaren Brücken, Stegen oder Wandbereichen aufweist, wobei die offenporige Oberflächenstruktur (14) eine erste Rauigkeit aufweist, und dass der Ankerabschnitt (6) anschließend an den Plateauabschnitt (4) in einem ersten axialen Ankerbereich (20) umfangsseitig eine in einer radialen Richtung (12) hinterschnittfreie, das heißt von hintergreifbaren Brücken und brückenbildenden Stegen freie Oberflächenstruktur (28) mit einer zweiten Rauigkeit aufweist, die geringer ist als die erste Rauigkeit, und dass der Ankerabschnitt (6) in der axialen Richtung (10) anschließend an den ersten axialen Ankerbereich (20) einen zweiten axial frei endenden axialen Ankerbereich (22) mit einer glatten Oberfläche aufweist.

PATIENT INTERFACE

Resumen de: AU2026201217A1

A patient interface comprises a support structure and a seal-forming structure. The support structure is arranged to support the sealing portion and is configured to connect to the frame. The sealing portion comprises textile and is attached to the support structure along an outer perimeter of the sealing portion such that in use the sealing portion may be in tension due to reactive stress of the support structure and/or a resilient stretch characteristic of the textile such that the sealing portion exerts a force against the patient’s face. eb e b

SYSTEM AND METHOD FOR PERFORMING QUALITY ANALYSIS FOR MULTIDIMENSIONAL PRINTING

Resumen de: US20260070279A1

A system for performing quality analysis for multidimensional printing. The system includes a multidimensional printer, wherein the multidimensional printer comprises a printing head, a printing surface, an axis system and a scale, wherein the scale is arranged to measure weight applied on the printing surface; and a control unit operatively coupled to the multidimensional printer. The control unit is configured to control the printing head to extrude a printing material, to produce a printed object on the printing surface, obtain, from the scale, a weight of the printed object, and store the weight of the printed object in a memory associated with the control unit, compare the weight with a reference weight of the printed object, and control the printing head to stop extrusion of the printing material when the weight is equal to or exceeds the reference weight.

ARTICLES INCLUDING A MICROSTRUCTURED CURVED SURFACE, TOOLING ARTICLES, AND METHODS

Resumen de: US20260070777A1

The present disclosure provides a microstructured article including a thermoplastic polymer shaped to have a curve. At least a portion of the curve includes a microstructured surface of utilitarian discontinuities and the microstructured surface includes peak structures and adjacent valleys. The peak structures and the curve are formed of a single piece of the thermoplastic polymer. A method of making the microstructured articles is also provided including a) obtaining a tool shaped to include at least one of a protrusion or a concavity; b) disposing a microstructured film on at least a portion of the tool including the protrusion and/or the concavity; and c) thermoforming a single piece of thermoplastic polymer onto the tool to form a microstructured article shaped to include a curve. The curve is an inverse of the protrusion or the concavity of the tool.

MOLECULARLY CLEAVABLE BIOINK FORMULATION

Resumen de: US20260071187A1

A bioink formulation for digital light processing bioprinting comprising a mixture of a biocompatible cleavable polymer precursor, a biocompatible non-cleavable polymer precursor, and a photoinitiator is described. Three-dimensional (3D) objects prepared using these bioink formulations are also described. In addition, a method of 3D bioprinting is described. The method includes providing a bioink formulation in a 3D bioprinter vat; repeatedly photoactivating the biocompatible photoactive polymer precursors in the 3D bioprinter vat on a build plate immersed in the vat to form a 3D bioprinted object comprising polymers having a series of predefined shapes across the vertical direction based on a set of sliced images; and treating the 3D bioprinted object with an agent that cleaves chemical bonds within the cleavable polymer.

AUGMENTED REALITY SCANNING INTERFACE FOR GENERATING PERSONALIZED 3D PRINTED CASTS

Resumen de: US20260069145A1

A method of generating a 3D model of a body part includes scanning the body part with a 3D scanner; during the scanning step, generating, with an augmented reality user interface, an augmented reality view of said body part, wherein the augmented reality view differentiates between portions of the body part that have already been scanned and portions that have not yet been scanned; with guidance from the augmented reality view, completing the scan; and generating the 3D model based on data received from the scan. The augmented reality view is displayed on a practitioner-facing screen incorporated into the scanning device. The method may further include imaging the body part with a thermal imager and overlaying thermal scanning data onto the 3D model to thereby generate a distribution map of thermal sensitivity on the 3D model. The design is then generated with holes situated to maximize thermal comfort.

METHODS OF FABRICATING LASER-SINTERED CARBOHYDRATE MATERIALS AND COMPOSITIONS AND USES THEREOF

Resumen de: US20260070282A1

A composition useful in forming a structure in the form of a substantially interconnected vascular network. The composition includes a powder including a carbohydrate powder and an anti-caking agent, where the powder: has a granular form, and has a specific energy of less than 6 millijoules per milliliter (mJ/mL).

TWO-PHASE 3D PRINTING OF BIOCOMPATIBLE STRUCTURES

Resumen de: US20260069744A1

A method of printing a hydrogel scaffold is provided which includes providing a container containing an ink and a liquid that is immiscible with the ink; applying light from a light source to the ink to form a portion of the hydrogel scaffold; and applying light from a light source one or more additional times to produce one or more additional portions of the hydrogel scaffold.

SYNTHETIC BONE GRAFTS AND METHODS FOR THEIR PREPARATION

Resumen de: US20260069746A1

The present invention provides methods for the preparation of synthetic bone grafts which are made of a composition comprising two matrixes, one ceramic including interlocked CDHA crystals, and another of one or more binder(s), the two matrixes being admixture. The method comprises the preparing of an ink composition, the 3D-printing, and the hardening of the binder and ceramic components, in this order.The resulting bone grafts, which are characterized by including the two matrixes in admixture, shows improved mechanical properties as well as excellent biological properties.

SUCTION TOOTHBRUSH AND RELATED METHODS

Resumen de: US20260069028A1

A suction toothbrush includes a handle defining an opening, a toothbrush head including internal channels, a seal with a distal end received within the toothbrush head and a proximal end coupled to the handle through the opening thereof, and a connector extending through the annular body of the seal. The connector includes a main body having a distal end disposed within the internal conduit of the toothbrush head and a proximal end extending into the handle through the top opening thereof, and a vibration motor housing offset from the proximal end of the main body. A waste reservoir for a suction toothbrush includes a lid, a basin defining a sump for waste material, and a gas-permeable membrane disposed between the lid and the basin that defines central inlet opening. A 3-D printing method for suction toothbrush heads.

SYSTEM AND METHOD FOR PRODUCING PHARMACEUTICAL OBJECTS VIA 3D PRINTING

Resumen de: US20260069503A1

Method for 3D printing, comprising the following steps: providing a packaging (2′) having at least one recess (3′) for receiving a product (1′), wherein the shape of the recess (3′) corresponds at least in part to the shape of the product (1′) and wherein the recess (3′) forms a protuberance at the other side of the packaging (2′); providing a 3D printer with a print base (5′) having at least one recess (6′) for receiving the protuberance formed by the recess (3′) of the packaging (2′); inserting the packaging (2′) in the print base (5′) such that the protuberance formed by the recess (3′) of the packaging (2′) is received by the recess (6′) of the print base (5′); filling a print head (7′) of the 3D printer with at least one material for printing the product (1′); 3D printing the product (1′) inside the recess (3′) of the packaging (2′), wherein the part of the recess (3′) corresponding to the shape of the product (1′) serves as the mold and print support, resp., for those layers of the product (1′) which are 3D printed first. The method is performed with a system for 3D printing, comprising a packaging (2′) having at least one recess (3′) for receiving a product (1′), wherein the shape of the recess (3′) corresponds at least in part to the shape of the product (1′) and wherein the recess (3′) forms a protuberance at the other side of the packaging (2′); and a 3D printer with a print head (7′) and a print base

TIBIA IMPLANT

Resumen de: US20260069422A1

A tibia implant for joint replacement has a plateau section and an anchor section projecting from a tibia-facing side of the plateau section. The anchor section is insertable into a channel in a tibia bone. The plateau section has a first surface structure that is a porous open-pore surface structure with bridges, webs or wall regions that can be gripped from behind in the axial direction on the tibia-facing side that comes into contact with tibia bone tissue. The open-pore surface structure has a first roughness. The anchor section is connected to the plateau section in a first axial anchor region on the circumferential side has a surface structure with a second roughness that is lower than the first roughness. The anchor section has a second axially free-ending axial anchor region with a smooth surface in the axial direction adjacent to the first axial anchor region.

DENTAL APPLIANCES WITH INTERPROXIMAL ENGAGEMENT STRUCTURES

Resumen de: US20260069385A1

Dental appliances and associated systems are provided. In some embodiments, a dental appliance includes a shell configured to receive a plurality of teeth, the shell having a sidewall and an interproximal engagement structure extending from the sidewall into a space of an interproximal region between a first tooth and a second tooth of the plurality of teeth. The interproximal engagement structure can be configured to contact the first tooth and the second tooth concurrently. The interproximal engagement structure can be larger than the space of the interproximal region, such that the contact causes deformation of one or more of the interproximal engagement structure or the sidewall.

MULTI-MODAL PATIENT-SPECIFIC SURGICAL GUIDES

Resumen de: US20260069290A1

A surgical device includes a first body component including at least one insert embedded therein and a second body component including a patient-specific surface. The first body component includes a first material and the at least one insert includes a second material. The first body component defines at least one first hole and the second body component defines at least one second hole. The second body component is configured to be coupled to the first body component such that the at least one first hole and the at least one second hole are aligned when the first body component is coupled to the second body component to define at least one continuous fixation hole sized and configured to receive an elongate fixation device at a predetermined location.

MEDICAL DEVICES AND RELATED METHODS

Resumen de: US20260069260A1

A medical device includes an operating member, a hub, and an end effector. The operating member includes an actuation portion. The hub includes a channel receiving the actuation portion of the operating member. The actuation portion of the operating member moves within the channel. The end effector is movable between a closed configuration and an open configuration. Distal extension of the operating member transitions the end effector to the open configuration, and proximal retraction of the operating member transitions the end effector to the closed configuration. The medical device is formed through an additive manufacturing process.

DESIGN METHOD OF TRANSPARENT ORTHODONTIC DEVICE AND ATTACHMENT FOR ORTHODONTICS

Resumen de: EP4706587A1

The method for designing a transparent orthodontic appliance and attachment for tooth alignment according to the present invention has been devised to solve the above technical problems. It is a method for designing an orthodontic appliance using a computer, comprising: a step (S01) of designing the shape of an attachment to be affixed to the surface of a tooth model; a step (S02) of designing the inner surface shape of the transparent orthodontic appliance corresponding to the attachment designed in step S01; and a step (S03) of outputting the transparent orthodontic appliance by means of a 3D printer. The attachment comprises: two pressure surfaces (101) formed to face each other; two inclined surfaces (201) formed to be inclined toward each other while contacting the two pressure surfaces (101); a top surface (301) contacting the edges of the two pressure surfaces (101) and the two inclined surfaces (201); and an attachment surface (401) affixed to the surface of a tooth. This configuration serves as the technical means for solving the problem.

METHOD FOR MANUFACTURING ORTHODONTIC DEVICE BY USING INSERTION PATH

Resumen de: EP4706586A1

The present invention relates to a program for designing an orthodontic appliance. The method comprises: displaying, on a screen, the insertion path for determining the insertion direction of the appliance (S01); designating a tooth targeted for the insertion path setting (S02); setting the insertion path for the designated tooth in an arbitrary direction (S03); displaying, on the screen, undercuts of each tooth caused by the set insertion path (S04); calculating and storing depth values of the undercuts for each tooth (S05); and calculating and storing the total sum of undercut volumes for each tooth according to the insertion path (S06).

SEMICRYSTALLINE SULFUR CONTAINING POLYMERS FOR ORTHODONTIC APPLICATIONS

Nº publicación: EP4704757A1 11/03/2026

Solicitante:

ALIGN TECHNOLOGY INC [US]
Align Technology, Inc

Resumen de: US2025009476A1

The present disclosure provides polymeric materials comprising semicrystalline sulfur-containing polymers, methods and curable compositions for making the same, and orthodontic appliances made from said polymeric materials.