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174
resultados
Última actualización
12/12/2025 [07:36:00]
Resumen de: DE112024000859T5
Enthalten ist ein computerimplementiertes Verfahren zum Schließen eines oder mehrerer Löcher in einem unteren Abschnitt eines dreidimensionalen digitalen Präparationsmodells einer Zahnpräparation. Der Zahn ist für die Aufnahme eines Zahnrestaurationselements präpariert, wobei eine untere Grenze des unteren Abschnitts der Präparation in Form einer stufenlosen Kante präpariert ist. Das Verfahren umfasst den Empfang des dreidimensionalen digitalen Präparationsmodells des präparierten Zahns. Ein oder mehrere zu schließende Löcher des dreidimensionalen digitalen Präparationsmodells werden innerhalb des unteren Abschnitts erfasst. Es wird ein Präparationswinkel für die Präparation des unteren Abschnitts bestimmt und das oder die erfassten Löcher werden geschlossen. Das Schließen umfasst eine Extrapolation des unteren Abschnitts in die Löcher unter Verwendung des ermittelten Präparationswinkels.
Resumen de: EP4659714A2
There is provided a prosthetic finger, comprising: a knuckle (165) that attaches to a prosthetic socket (194); a first phalange (155) having a phalange end coupled to the knuckle (165) and configured to move in flexion and extension with respect to the knuckle (165); a distal phalange (160) coupled to the first phalange (155) and configured to move in flexion and extension; a link bar (170) extending through the first phalange (155) and having: a first link bar end coupled to the knuckle; and a second link bar end coupled to the distal phalange; and a ratcheting mechanism (157) comprising: a set of teeth (167); and a release lever (175) that moves between a first position and a second position, wherein: in the first position, the release lever is engaged with the set of teeth and prevents movement of the first phalange and the distal phalange in extension; and in the second position, the release lever is disengaged with the set of teeth and allows movement of the first phalange and the distal phalange in extension.
Resumen de: US2024252719A1
A method for in-vivo cell replacement is disclosed. The method includes steps of extracting donor cells from a donor tissue of a patient; generating donor material including the donor cells; removing one or more cell layers from a receiver tissue of the patient to expose a target layer of the receiver tissue while maintaining operation of a vasculature of the receiver tissue; and printing the donor material onto the target layer of the receiver tissue. A tissue position assembly, a composition for use in a treatment of bladder damage or bladder dysmorphism, and a system for supplying donor material to a bioprinter are also disclosed.
Resumen de: EP4659719A1
Dispositif médical (100,200,300,400) pour immobiliser un membre ou une articulation, ledit dispositif comportant au moins deux demis-coques complémentaires (10a-b,20a-b,30a-b,40a-b) de forme sensiblement alvéolaire, lesdites demis-coques comprenant chacune au moins deux surfaces de contact (101a-b,102a-b,201a-b,202a-b,203a-b,301a-b,302a-b,303a-b,401a-b,402a-b), un système de fermeture (12,22,32,42), le système de fermeture (12,22,32,42) étant positionné dans des logements (103a-b,204a-b,304a-b,403a-b) des surfaces de contact (101a-b,102a-b,201a-b,202a-b,203a-b,301a-b,302a-b,303a-b,401a-b,402a-b), ledit système de fermeture étant magnétique, ledit système de fermeture étant invisible lorsque le dispositif médical (100,200,300,400) est assemblé.
Resumen de: WO2024163434A1
A collimator assembly for a linear accelerator for use in FLASH radiotherapy includes a collimator and a tray. The collimator includes an elongated body and a base and can also include an opening that defines a central bore formed in the elongated body and the base and extending the length of the collimator along a central axis. The tray includes a central opening having a larger cross-section than the elongated body of the collimator but smaller than the base of the collimator to allow only the elongated body of the collimator to pass therethrough such that the collimator is retained by the tray for reversible installation on the linear accelerator. The tray is adapted to be removably installed on accessory rails of the linear accelerator. Both the collimator and tray may be fabricated by 3D printing to allow for customization.
Resumen de: CN120603620A
A drug delivery device comprises at least one tissue penetrating member configured to be embedded in tissue, the at least one tissue penetrating member comprising: at least one lumen formed below an outer surface of the at least one tissue penetrating member, the at least one cavity has a depth from the outer surface and a width in a direction orthogonal to a direction of the depth from the outer surface; and at least one opening in the outer surface, the at least one opening in communication with the at least one lumen such that at least one API loaded into the at least one lumen can be absorbed from the at least one lumen into the tissue, where the width of the at least one opening is less than the width of the at least one lumen.
Resumen de: CN120641167A
A drug delivery device comprises at least one tissue penetrating member configured to be embedded in tissue, the at least one tissue penetrating member comprising: a plurality of lumens, and at least one payload comprising at least one active pharmaceutical ingredient (API) loaded into the plurality of lumens, the at least one tissue penetrating member is configured such that when the at least one tissue penetrating member is embedded in the tissue, the at least one API can be absorbed into the tissue wherein a ratio of a surface area of the plurality of lumens to a volume of the plurality of lumens is at least 0.5: 1.
Resumen de: CN120712122A
A drug delivery device includes a substrate; and a plurality of tissue penetrating members 3D printed onto the substrate and configured to be embedded into tissue, wherein at least one tissue penetrating member of the plurality of tissue penetrating members is configured to anchor the drug delivery device to the tissue; and at least one payload comprising at least one API loaded into at least one of the substrate and the plurality of tissue penetrating members for absorption into the tissue when the at least one tissue penetrating member is embedded in the tissue.
Resumen de: EP4661024A2
Methods and apparatuses, including systems, for forming and modifying treatment plans, including modifying treatment plan in real time. In particular are methods and apparatuses for modifying and orthodontic treatment plan in real time that may include the use of an enhanced user interface including a 3D user overlay.
Resumen de: EP4659703A2
The present disclosure relates to single tooth or full arch dental restoration. In cases where patients have insufficient bone stock for conventional root-form dental implants, current solutions often fail to restore function. The present disclosure describes a transalveolar dental implant for single tooth or full arch dental restoration. The transalveolar dental implant is comprised of a post and a bone plate, the bone plate having a contoured portion fabricated to match the topography of a bony surface of the facial skeleton. Through primary fixation of the contoured portion of the bone plate, the transalveolar dental implant improves function and outcomes in affected patients.
Resumen de: WO2024163970A2
The various embodiments described herein include methods, devices, and systems for customizing dental care. In one aspect, personalized toothbrush devices are 3-D printed for a plurality of users. A 3-D dental model of a respective user's mouth is obtained, and a configuration for a mouthpiece of a respective personalized toothbrush device is determined. The respective personalized toothbrush device is 3-D printed, and includes a top cleaning tray, a bottom cleaning tray, and a set of cleaning elements, each customized based at least in part on the 3-D dental model of the respective user's mouth. Each personalized toothbrush device is 3- D printed for each respective user of the plurality of users, and is different from every other user's personalized toothbrush device.
Resumen de: CN121095468A
本申请涉及口腔种植引导技术领域，提供了一种基于数字化建模的可快速脱拆义齿系统及其制作方法。该方法包括：通过口腔扫描仪获取患者口腔内三维数据，通过神经辐射场模型对患者口腔内结构进行三维重建；在三维口腔模型中设置虚拟替代体，构建可拆义齿的虚拟实体；从三维口腔模型中提取可拆义齿参数及虚拟实体与虚拟替代体之间的初始位置关系；结合初始位置关系及与口腔就诊相关的患者个体化数据，采用位移预测模型预测可拆义齿在咬合过程中符合长期使用状态的位移变化趋势获得修正策略；采用修正策略优化可拆义齿参数及对应的初始位置关系，由用户端确认后通过义齿制造端生产匹配的可拆义齿定制化模型，提升可拆义齿与患者口腔的适配度。
Resumen de: CN121081154A
本发明属于医疗器械技术领域，公开了一种3D打印颌骨囊肿塞治装置及其制作方法，该装置包括术中定位导板和术后囊肿塞治器。其制作方法包括：获取患者颌骨三维影像数据和牙列三维扫描数据；在计算机中对数据进行重建、分割和精确配准，生成融合数字化模型；基于该模型个性化设计导板和塞治器；最后通过3D打印机制造出实体装置。本发明采用全数字化工作流程，能够在术前一次性完成导板和塞治器的精确设计与制作，省去了传统术后取模的繁琐步骤，提高了制作效率和装置的适配精度，使手术更精准、微创，同时提升了患者的佩戴舒适度和治疗效果。
Resumen de: CN121081747A
本发明公开了一种功能性可降解大豆油基仿生多孔复合骨支架的制备方法和应用。该方法以环氧大豆油丙烯酸酯为生物基基材，复配甲基丙烯酸异冰片酯以改善其高粘度、低光敏性缺陷，加入光引发剂包含2,4,6‑三甲基苯甲酰基苯基膦酸乙酯与苯基双（2,4,6‑三甲基苯甲酰基）氧化膦复配后经老化处理得到基料树脂；再将木质素磺酸钙掺入基料树脂中制得复合光敏树脂，通过数字光处理技术3D打印技术打印三重周期极小曲面结构，最终得到功能性可降解豆油基仿生多孔支架。该支架兼具木质素磺酸钙介导在模拟人体内环境的条件下表现出近红外光光照调控与骨支架组分依赖的可控的光热响应行为，从而实现可控的光热响应介导的远程形状记忆功能的同时还可以实现温和的、安全可控的光热疗效。此外，木质素磺酸钙在改善支架亲水性能的同时，通过优先溶解并使得基体表面产生微孔结构而促进复合支架降解，并持续释放钙离子，由此使支架表现出增强的生物矿化能力并促进了细胞增殖和成骨分化。本研究为大豆油基生物光敏材料在仿生多孔骨支架的数字光处理制备技术以及多功能化应用中提供了一种具有潜力的解决方案以应对复杂不规则的骨缺损。
Resumen de: CN116687591A
The invention provides a pressed film model for manufacturing an appliance, the pressed film model comprises a tooth jaw prototype and an accessory model on the tooth jaw prototype, the accessory model comprises a connecting part and an accessory part, a gap is formed between the accessory part and the tooth jaw prototype, the connecting part is located in the gap and used for connecting the accessory part and the tooth jaw prototype, and the connecting part is located in the gap and used for connecting the accessory part and the tooth jaw prototype. When force larger than a preset value is applied to the connecting part, the connecting part is broken, and therefore the accessory part is separated from the tooth jaw prototype. Through the arrangement of the breakable connecting part in the pressed film model, the demolding difficulty of the appliance can be reduced, and the appliance is prevented from deforming or cracking in the demolding process. Meanwhile, the invention further provides a manufacturing method of the pressed film model for manufacturing the appliance and a manufacturing method of the appliance.
Resumen de: CN121081171A
本发明涉及生物医学新材料技术领域，提供一种结构功能一体化仿生椎间融合器制备方法和装置，借计算机辅助设计与拓扑优化算法确定支架的初始多孔结构骨架。选用可降解金属材料粉末作支架材料，制成三维多孔结构的支架坯件，选生物玻璃等作涂层靶材，激光作用下形成均匀可控的熔融玻璃液滴，气流带动液滴定向输送至多孔支架，穿透外部孔隙沉积于内部孔隙表面。多孔支架旋转与气流协同实现三维多向表面涂敷，最终得到支架融合器。本发明还公开了一种用于上述方法的装置。该方法和装置能够在复杂结构处理与性能调控领域，能突破传统线扫描或渗透式涂层方法难以在复杂拓扑结构内部实现均匀涂覆的瓶颈，适用于不同宏观拓扑结构和孔隙尺寸的多孔支架。
Resumen de: CN121081743A
本发明提供了一种基于大分子拥挤效应的重组Ⅲ型人源化胶原蛋白凝胶及其制备方法与应用。首先配制rhCol III溶液体系；随后配制包含右旋糖酐70、聚乙二醇8000及抗坏血酸的大分子拥挤浴；再将rhCol III溶液加入上述大分子拥挤浴中以形成rhCol III微凝胶；最后构建以琼脂糖为基底、含功能添加剂以及温敏聚合物作为温敏释放与空间约束组件的3D打印分子排阻模具系统，实现rhCol III微凝胶的定向构建。本发明实现rhCol秒级物理成胶（<15 s），并构建了支持细胞增殖的生理微环境。本发明制得的重组Ⅲ型人源化胶原蛋白凝胶可用于制备胶原微凝胶球，胶原束，3D生物打印等产品，应用范围广泛。
Resumen de: CN121081744A
本申请提供了一种聚乳酸/丝蛋白3D打印气管支架的制备方法，属于医疗器械技术领域。本申请将聚乳酸和热塑性淀粉按特定比例混合，造粒，接着熔融挤出、牵伸，得到复合线材，再经熔融沉积3D打印，并依次于聚乙二醇（PEG）和丝素蛋白水溶液中浸泡，得到聚乳酸/丝蛋白气管支架。相比常规PLA线材成分简单可控。通过引入热塑性淀粉对PLA的熔融指数和结晶速率进行调控，改善其可打印性和打印样品的稳定性。用PEG进行浸泡，PEG分子可渗入气管支架，使支架发生轻微溶胀软化，提高支架的亲水性。将丝蛋白涂敷在支架表面，提高支架生物相容性。采用熔融沉积3D打印工艺，比直写式3D打印工艺更加稳定，更利于制备性能均一稳定的气管支架。
Resumen de: CN121081750A
本发明公开了一种用于创面修复的声波辅助3D打印复层高密度细胞贴片及其制备方法，该方法将定制的声波平台、信号发生器、功率放大器和3D打印机结合，信号发生器产生的正弦波通过功率放大器被放大，经过声波平台上的指间交叉换能器将电信号转变为声波信号，信号通过具有正逆压电效应的基板在生物墨水中产生机械能，将细胞聚集在打印平台中心，从而生物打印形成复层高密度细胞贴片；通过更换不同细胞种类的生物墨水，改变打印参数逐层打印三种细胞，制备得到复层高密度细胞贴片。本发明制备的复层高密度细胞贴片特征在于具有仿人体皮肤的三层结构和人体内细胞的高密度，具有诱导细胞迁移、促进血管生成，改善炎症反应，从而加速创面愈合的优点。
Resumen de: CN121059320A
本发明公开一种复合牙颌模型，包括：上颌牙颌模型、下颌牙颌模型和能够锁定上下颌相对位置关系的定位组件；上颌牙颌模型包括上颌牙齿部和支撑上颌牙齿部的上颌支撑部；下颌牙颌模型包括下颌牙齿部和支撑下颌牙齿部的下颌支撑部；定位组件包括与上颌支撑部连接的上颌定位件和与下颌支撑部连接的下颌定位件；其中，上颌定位件和下颌定位件直接装配或间接装配后，能够将复合牙颌模型的上下颌相对位置定位至患者目标颌位的对应位置。本发明还提供了复合牙颌数字模型的设计方法，以及牙科器械的制作方法。
Resumen de: CN119947675A
The invention relates to a method for producing a tooth substitute part (200) that can be connected to a tooth stump (110), in particular a stationary tooth substitute part (200), wherein an adapter (10) for a machine tool and a blank (50) for a tooth substitute part (200) are produced.
Resumen de: FR3162625A1
L’invention est relative à une formulation pharmaceutique adaptée à la fabrication de doses unitaires d’un médicament solide ou semi-solide par impression 3D, à une cartouche d’impression renfermant une telle formulation pharmaceutique à l’utilisation de cette formulation pharmaceutique pour la fabrication de doses unitaires d’un médicament solide ou semi-solide par impression 3D, à une cartouche d’impression renfermant une telle formulation pharmaceutique, et à un procédé de préparation d’un médicament sous la forme de doses unitaires par impression 3D mettant en œuvre une telle formulation. Figure à publier avec l’abrégé : 1
Resumen de: CN223627552U
本申请涉及医疗器械的技术领域，尤其是涉及一种胫骨近端截骨器具，其包括截骨导板，所述截骨导板包括导板主体和护套，所述护套设于所述导板主体的周向，所述导板主体和所述护套共同覆盖患部胫骨近端端面；克氏针固定孔，设置在导板主体上，用于引导克氏针钉入患者胫骨以固定所述导板主体；髓针定位孔，设置在导板主体上，用于定位假体髓针的位置；刀槽，设置在所述护套上，用于引导截骨工具进行截骨。本申请具有将髓针的定位与截骨两个步骤合二为一，节省手术时间，减少感染概率的效果。
Resumen de: WO2024188675A1
The invention relates to an apparatus for producing three-dimensional screen-printed workpieces, in particular a 3D screen printing installation, said apparatus comprising: a printing device for the layer-by-layer production of at least one screen-printed workpiece in a plurality of printing operations; and a drying device which is designed to dry at least one screen-printed workpiece and to simultaneously cool a workpiece carrier that carries the screen-printed workpiece to be dried.
Nº publicación: CN121079191A 05/12/2025
Solicitante:
埃克森蒂斯知识股份有限公司
Resumen de: WO2024188677A1
The invention relates to a workpiece carrier, in particular for producing three-dimensional screen-printed workpieces, said workpiece carrier comprising: at least one printing bed which has a printing surface to be printed; and a support structure which supports the printing bed and is formed separately from the printing bed, the support structure having a support base and at least one stop for the printing bed, the printing bed being arranged on the support base, and it being possible to bring the printing bed, when in the position arranged on the support base, into contact with the stop in at least one lateral direction.
BOPI
Sede Electrónica
