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METHOD FOR PRODUCING THREE-DIMENSIONAL MANUFACTURED PRODUCT

Resumen de: US2025083380A1

Provided is a method for producing a three-dimensional manufactured product, the method including: a shaping step of performing a vat photopolymerization process using a liquid photocurable composition containing a radically-polymerizable monomer, an inorganic filler, a photopolymerization initiator, an activating light absorbent, and a polymerization inhibitor, to obtain a shaped product having a shape corresponding to the shape of a target article and containing an effective amount of the photopolymerization initiator in the interior thereof; and a post-polymerization step of irradiating the shaped product with activating light at an irradiation intensity of 10 to 10,000 mW/cm2, and then heating the shaped product at a temperature of 50° C. or higher and lower than 110° C., to polymerize an unpolymerized component contained in the shaped product. Further, provided is a method for producing a dental restoration, including producing the dental restoration according to this method for producing a three-dimensional manufactured product.

METHODS OF MAKING AN ORAL APPLIANCE

Resumen de: US2025082451A1

An oral appliance and a method of making the oral appliance for delivering a medicament to an oral cavity are provided. The method comprises forming a non-porous material into a portion of the oral appliance; and applying a porous material to one or more discrete regions of the portion of the oral appliance to make the one or more discrete regions of the oral appliance porous thereby forming the oral appliance.

PATIENT INTERFACE

Resumen de: US2025082885A1

A patient interface comprises a frame which defines, at least in part, a plenum chamber, and a positioning and stabilising structure comprising at least one headgear tube. The frame, at least one headgear tube and manifold portion are integrally formed. In examples, no part of the frame or headgear tube has a Shore A Durometer hardness greater than 80. A method of manufacturing a component for a patient interface from a textile is also disclosed.

Pressure Gauge Plunger for Platforms for Extrusion-Based 3D Printing of Semisolid Masses

Resumen de: US2025083390A1

The pressure gauge plunger for 3D printing platforms is applicable in various 3D printing fields (bioprinting of tissues; and the food, pharmaceutical, and ceramic industries). Its usefulness is rooted in its ability to continuously control the pressure applied during the entire printing process, thanks to the plunger mechanism. It thereby allows improved quality and detection of errors in situ, allowing corrective actions to be applied during the process. The pressure value that the printing platform component exercises on the plunger (and, thus, on the mass to be extruded) is obtained through use of a stress gauge, This continuous control allows profiling of the printed semi-solid mass, permitting the most appropriate printing parameters to be set in situ, further allowing the process to become completely automated.

SYSTEM AND METHODS FOR TREATING A 3D PRINTED PROSTHETIC LINER

Resumen de: WO2023215504A1

The inventive technology disclosed herein relates to improved 3D printed prosthetic liners adapted to provide an interface between a residual limb and a prosthetic socket. The present invention includes novel methods for manufacturing and treating a prosthesis device, and in particular a 3D printed prosthetic liner. In one preferred aspect, the invention includes the manufacture of a prosthetic liner using a 3D printing device, the surface of which may be treated with one or more applications of a casting resin, and preferably a urethane-based casting resin forming a treated prosthetic liner having enhanced strength and pliability.

FORMULATIONS AND MEDICAL DEVICES FOR MINIMALLY-INVASIVE DEEP TISSUE APPLICATIONS

Resumen de: US2024139380A1

Viscoelastic hydrogel microparticles are used for repair of tissue defects and injuries or filling and occlusion of anatomical structures. These are administered as a microparticle suspension using a catheter, syringe, steerable catheter tip, or comparable technology into the site, where they can be further stabilized by crosslinking or sealing, or through incorporation of a support or encapsulating structure. Materials and methods for solidifying, stabilizing and sealing these materials can be used that are also biocompatible and easily deployed with catheters in the body. The micron sized interstitial spacing provides a scaffold for ingrowth and migration of cells into the gel matrices.

BONE FIXING DEVICE

Resumen de: CN118891012A

The present invention relates to a fixation device which is particularly suitable for engagement in a suitable bone site in the case of regenerative and/or reconstructive surgery, such as spinal surgery or trauma surgery.

PROCESS FOR PRODUCING A THREE-DIMENSIONAL STRUCTURE

Resumen de: WO2023214362A1

The present invention relates to a process for producing a three-dimensional structure comprising the steps of: a) providing a light source; b) coupling said light source to a proximal end of at least one optical fibre, in such a way as to propagate the light generated by said light source through the optical fibre and produce, at a distal end of the optical fibre, a predetermined incident optical field, wherein said optical field maintains the same phase profile, the same spatio-temporal intensity, and the same frequency during propagation of light through the optical fibre and during exit from the optical fibre; c) providing at least one photo-crosslinkable polymeric material coated with at least one transparent material, wherein the transparent material comprises a first surface placed in contact with the photo-crosslinkable polymeric material and a second surface placed not in contact with the photo-crosslinkable polymeric material and opposite to the first surface; d) placing the distal end of the optical fibre at a distance D from the second surface of the transparent material, where D ranges from 0 mm to 5 mm; e) irradiating the second surface of the transparent material with the light propagated and exiting the distal end of the optical fibre for a period of time between 1 second and 5 minutes, so as to obtain propagation of the light through the transparent material towards the photo-crosslinkable polymeric material and to obtain photo-crosslinking, by irradiation, o

PROSTHESIS COVER AND METHOD FOR PRODUCING A PROSTHESIS COVER

Resumen de: WO2023213651A1

The invention relates to a prosthesis cover having at least one fastening device (20) for securing the prosthesis cover (1) to a prosthesis component (2), and a flexible main body (10) which has an inner side (11) facing the prosthesis component (2) in the applied state and an outer side (12) opposite the inner side (11), on which outer side the at least one fastening device (20) is arranged, wherein at least one structural element (30) protruding from the outer side (12) is applied to the outer side (12) in an additive manufacturing process.

RADIATION-CURABLE COMPOSITION FOR USE IN A RAPID PROTOTYPING PROCESS OR A RAPID MANUFACTURING PROCESS

Resumen de: WO2023213699A1

The invention relates to a polymerisable, radiation-curable composition, in particular a UV/Vis-curable, UV-curable or Vis-curable composition comprising (i) monomers and (ii) at least one further component, wherein the (i) monomers comprise (a) at least one urethane (meth)acrylate that is at least difunctional, (b) at least one monofunctional acrylate having an alicyclic group and/or at least one monofunctional methacrylate having an alicyclic group, and (ii) the at least one further component comprises (c) at least one photoinitiator for the UV and/or visible range or a photoinitiator system for the UV and/or visible range. The composition according to the invention is suitable for producing dental prosthetic parts, orthopaedic instruments or dental pre-forms, which are characterised by a) a flexural strength of greater than or equal to 75 MPa, and/or b) a modulus of elasticity of greater than or equal to 2600 MPa, and/or c) a water absorption of less than 45 μg/mm3, wherein these dental prosthetic parts, orthopaedic instruments or dental pre-forms can be produced using a rapid prototyping process or using a rapid manufacturing or rapid tooling process.

IMPLANTABLE MEDICAL DEVICE WITH THERMOPLASTIC COMPOSITE BODY AND METHOD FOR FORMING THERMOPLASTIC COMPOSITE BODY

Resumen de: EP4520517A2

An implantable medical device is disclosed comprising a thermoplastic composite body having anterior, first lateral, second lateral, posterior, superior, and inferior surfaces, and at least one dense portion and at least one porous portion which are integrally formed. The at least one dense portion is formed of a first thermoplastic polymer matrix that is essentially non-porous, and which is continuous through a thickness dimension from the superior surface to the inferior surface. The at least one porous portion is formed of a porous thermoplastic polymer scaffold having a second thermoplastic polymer matrix which is continuous through the thickness dimension. A method for forming the thermoplastic composite body is disclosed comprising disposing a first powder mixture in a first portion of a mold, disposing a second powder mixture in a second portion of the mold, simultaneously molding the first powder mixture and the second powder mixture, and leaching porogen.

SOLID DOSAGE FORM PRODUCTION

Resumen de: EP4520323A1

The present invention provides methods of preparing solid dosage form, particularly pharmaceutical dosage forms, using extrusion and 3D-printing, as well as the solid dosage form itself, the compositions used to make said items, uses of the solid dosage forms, and containers used in their preparation.

ELECTRIC COMPONENTS INCLUDING COILS AND METHODS TO FABRICATE THE SAME BY 3D PRINTING

Resumen de: EP4521429A2

Electric components including coils and methods to fabricate the same by 3D-printing are disclosed. The method includes: 3D printing a magnetic material to form a magnetic channel comprising a magnetic core of the coil device; 3D printing a conductive material to form a conductive channel, including conductive windings of the coil device with turns surrounding the magnetic core; and 3D printing a non-magnetic electrically insulating material to form electrical insulation between the turns of the conductive windings of the coil device. In some embodiments functional structures of the electric component, including the turns of the conductive windings of the coil and the electrical insulation between the turns, are each printed with minimal in-layer feature size of at least two voxels of the 3D-printing. Some embodiments facilitate 3D-printing of flattened coil devices having low aspect ratio between their lengths along their magnetic axes and their widths perpendicular thereto.

UV TREATMENT APPARATUS

Resumen de: EP4521019A2

To provide a light treatment device that solves a problem caused by deflection of a housing. The light treatment device (100) includes: a light source (3) that irradiates a treatment object (4) conveyed along a conveyance path with ultraviolet light (L1); a housing (2a, 2b) having the light source (3) therein and having an opening (5i, 5o) through which the treatment object (4) is carried in or out; and a heat deflection reducer that reduces heat deflection of the housing (2a, 2b) surrounding the opening (5i, 5o).

一种用于下颌骨截骨手术的3D打印导板

Resumen de: CN222584588U

本实用新型提供了一种用于下颌骨截骨手术的3D打印导板，包括定位组件，所述定位组件包括上定位座、两个上固定杆、上卡座、两个钉孔、限位板、下定位座、下卡座、两个凹槽、两个固定钉、上限位槽和咬合座。本实用新型通过将边缘卡座和底部卡座分别卡接在下颌骨的后部边缘处和底部，然后将咬合座卡接在下颌骨的牙齿上，将下卡座卡接在下限位槽内，将上卡座卡入上限位槽，将限位板插入至上定位座内的安装槽内，然后调节上定位座与下定位座之间的距离，将固定钉插入至钉孔和定位孔，即可将限位板与上定位座固定连接，由于咬合座的位置被牙齿限定，因此导板主体的位置固定，在不对下颌骨造成损坏的情况下，实现了对导板主体的固定。

一种义齿用数字化种植打印基台

Resumen de: CN222584698U

本实用新型公开了一种义齿用数字化种植打印基台，涉及义齿打印基台领域。本实用新型包括基台、连接块和连接架，所述基台的顶部一侧设置有承接组件，所述承接组件包括第一承接板，所述第一承接板通过转动座与基台转动连接，所述承接组件的顶部另一侧设置有限位机构，所述限位机构包括安装框，所述安装框的内部通过滑杆滑动连接有限位块，本实用新型通过承接组件和限位机构，避免了传统打印过程中需要对基台进行拆卸和翻转的复杂步骤，只需简单地转动承接板和调整限位块，就能轻松完成义齿的承接和铲除，显著提升了操作的便捷性，还大大提升了3D打印的效率，由于无需进行基台的拆卸、翻转和重新安装，每次打印周期的时间被大幅缩短。

一种骨诱导材料及制备方法

Resumen de: CN119587747A

本发明属于材料制备技术领域，具体涉及一种骨诱导材料及制备方法。本发明首先提供一种骨诱导材料，所述骨诱导材料由一种经过表面改性的玻璃碳材料制备得到；经过表面改性后的玻璃碳材料具有珊瑚样或类珊瑚样形貌，所述珊瑚样或类珊瑚样形貌包含由纳米颗粒自组装形成的直线、弧线、分枝结构、圆环或类圆环结构和/或串珠状形貌；所述珊瑚样或类珊瑚样形貌中还包含不均一孔洞结构。本发明创新性地提出了碳材料可以有骨诱导作用，并证明由玻璃碳材料为基体制备的骨诱导材料具有加速骨组织修复再生的能力。

一种具有形状记忆效应的多孔双梯度骨支架及其制备方法

Resumen de: CN119587225A

本申请属于生物材料技术领域，具体公开了一种具有形状记忆效应的多孔双梯度骨支架及其制备方法，该多孔双梯度骨支架包括由记忆材料制成的具有多个结构层的多孔点阵结构，该多孔点阵结构的内部孔隙贯通，并且，多孔点阵结构的孔隙率呈现为双梯度变化。本申请的骨支架与骨骼的匹配度极佳，能够很好地适配人体皮质骨和松质骨的孔隙率和排布方式，并且，骨支架具有形状记忆效应，能够在植入患者体内前进行压缩，有效减小支架的尺寸，在手术过程中可以只在缺损部位打开一个较小的创口，在手术中植入人体之后发生形状回复，尺寸增大到压缩之前预定的匹配缺损部位的形状，与缺损部位完全匹配。

一种3D打印骨修复材料及其制备方法

Resumen de: CN119587753A

本发明属于医用材料技术领域，具体是提供了一种3D打印骨修复材料及其制备方法，3D打印骨修复材料由PCL/MnO2复合微球和SiN制备而成，PCL具有良好的生物相容性和生物降解性，SiN的加入，增强了3D打印骨修复材料的机械性能和骨诱导性能，改善了整体的降解速度，为新骨形成提供必要的空间，且有利于钙沉积，而MnO2可以释放氧气和锰离子，锰离子可以促进钙沉积，共同促进细胞浸润、成骨分化和基质矿化，促进骨前体细胞增殖，加速骨缺损修复，促进骨再生，本发明制备的3D打印骨修复材料具有良好的机械性能、生物相容性、抗菌性以及生物降解性，促进了细胞增殖，加速了骨修复和骨再生。

一种3D打印高强度明胶/碳酸二酰肼改性海藻酸钠天然高分子水凝胶及其制备方法和应用

Resumen de: CN119587754A

本发明公开一种3D打印高强度明胶/碳酸二酰肼改性海藻酸钠天然高分子水凝胶及其制备方法和应用，将明胶溶液和碳酸二酰肼改性海藻酸钠溶液共混得到明胶/碳酸二酰肼改性海藻酸钠墨水，然后将墨水3D打印后的水凝胶依次通过CaCl2溶液浸泡和EDC/NHS溶液浸泡交联进行顺序增强处理，得到高强度天然高分子水凝胶。该3D打印高强度天然高分子水凝胶体系还可以引入生物活性因子，从而制备满足临床需求的生物活性水凝胶支架。将负载促角膜上皮化的生长因子的生物墨水A和负载组蛋白去乙酰化酶抑制剂的生物墨水B通过一个多喷头3D打印系统的逐层打印可以得到生物活性双层水凝胶支架，用于角膜再生。该3D打印高强度天然高分子水凝胶的制备流程涉及的操作简单方便，并且该体系具有较强的可设计性和普适性。

膨張性の構造化された投薬剤形

Resumen de: US2024197644A1

In this specification, an expandable structured dosage form for prolonged drug delivery is disclosed. The dosage form comprises a three-dimensional structural framework of physiological fluid-absorptive, drug-containing elements surrounded by interconnected free space. Upon immersing in a physiological fluid, the fluid percolates interconnected free space between elements, and the three-dimensional structural framework expands with fluid absorption and releases drug overtime. The disclosed dosage form enables prolonged delivery of drug into the upper gastrointestinal tract and the blood at a controlled rate for improving the efficacy and safety of drug therapies.

一种DLP 3D打印浆料、多孔支架及其制备方法与应用

Resumen de: CN119564925A

本发明提供一种DLP 3D打印浆料、多孔支架及其制备方法与应用，所述DLP 3D打印浆料，按照质量百分比计，包括：含铜生物活性玻璃10%~70%，光敏树脂26.7%~87%，光引发剂0.3%~1%，分散剂2%~3%。其制备方法，包括：（1）将光引发剂、光敏树脂、含铜生物活性玻璃和分散剂混合均匀，得到混合液；（2）将所述混合液进行真空离心处理，得到DLP 3D打印浆料。本发明提高了多孔支架的质量和纯度，且可有助于促进细胞成骨相关基因的表达，提高促成骨能力。

一种个性化牙齿3D打印设备及其方法

Resumen de: CN119567556A

本发明公开了一种个性化牙齿3D打印设备及其方法，涉及3D打印技术领域，该方案包括机体，所述机体的顶部嵌入安装有旋转工作台，所述机体的顶部固定安装有U型架，所述U型架的外表面安装有XYZ移动机构，所述XYZ移动机构的活动端固定安装有旋转安装机构，所述旋转安装机构的内部安装有打印头，本发明通过设置的XYZ移动机构和旋转安装机构，不仅可以将打印头转动至水平状态并移至设备的前侧，方便维护人员有足够的空间进行操作，而且还可以快速实现打印头的安装和拆卸，通过设置的辅助成型机构，不仅可以充分对牙齿成型部分进行风冷散热，而且还可以在散热的过程中对牙齿进行灯光固化，可以加快牙齿的冷却成型速度，从而提高工作效率。

一种牙体制备的3D打印智能备牙设备

Resumen de: CN119567385A

本发明公开了一种牙体制备的3D打印智能备牙设备，属于牙体制备技术领域，包括打印设备本体以及套设在打印设备本体上的输送齿盘，输送齿盘的底端通过转动连接的支撑台设置在地面上，地面上设置有驱动电机，驱动电机的输出端固定连接有与输送齿盘啮合的驱动齿轮，打印设备本体的顶端圆周设置有多个放置座，放置座的顶端设置有固定盘。本发明通过设置有输送齿盘，输送齿盘上设置多个放置座，在其中一个放置座配合打印设备本体对瓷块进行剪切时，其余放置座可以进行瓷块定位固定，使得待打印的瓷块轮流经过打印设备本体，使得陶瓷牙体的打印、烧结以及上釉形成流程化，显著提高陶瓷牙体打印效率。

具有协同信号分子的冷冻3D打印支架及其制备方法和应用

Nº publicación: CN119564926A 07/03/2025

Solicitante:

中国科学院福建物质结构研究所

Resumen de: CN119564926A

本发明属于骨组织工程领域，尤其涉及一种具有协同信号分子的冷冻3D打印支架及其制备方法和应用，具有协同信号分子的墨水组合物包括负载有CO分子前药的第一多孔载体、负载有NO分子前药的第二多孔载体，所述第一多孔载体表面包覆有第一包封层，所述第一包封层用于将CO分子前药封堵在第一多孔载体的孔隙中，且所述第一包封层能够在高氧活性条件下自降解并释放CO分子；所述第二多孔载体表面包覆有第二包封层，所述第二包封层用于将NO分子前药封堵在第二多孔载体的孔隙中，且所述第二包封层能够在酸性条件下自降解并释放NO分子。本发明的方法能够得到结构较完整，且及时血管化和稳定骨生成的支架。