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223
resultados
Última actualización
21/06/2025 [08:30:00]
Resumen de: CN120176914A
本发明提供一种压阻传感器阵列及其制备方法，属于柔性传感器技术领域，与现有技术相比，本发明具有器件可拉伸特性，压阻传感器具有抗应变干扰稳定性。采用光固化3D打印技术，制备出软硬结合的基底结构，使压阻传感器阵列具备本征可拉伸性，有助于适应复杂形变环境；通过设计负泊松比岛桥结构，显著提升了器件的整体拉伸性能，确保其在大应变下的可靠性；结合PU/MXene敏感材料和传感层微观圆锥结构的优化设计，大幅提高了传感器在压力加载时的电信号灵敏度，实现了更精确的力学响应；同时，利用3D打印技术制备的传感器阵列相比传统制备方法更加高效，工艺流程简单且易于规模化生产，具有显著的优势。
Resumen de: CN120173185A
本发明涉及一种3D打印丝素蛋白基温敏水凝胶及其制备方法与应用，属于水凝胶技术领域。本发明的制备方法包括以下步骤：S1、向溴化锂溶液中加入丝素蛋白和甲基丙烯酸缩水甘油酯进行交联反应，经透析、离心、冷冻干燥得到改性丝素蛋白；S2、将改性丝素蛋白、异丙基丙烯酰胺、光引发剂、阻光剂和水混合均匀，经离心脱泡得到光固化生物墨水；S3、通过DLP 3D打印技术，将光固化生物墨水制成3D打印丝素蛋白基温敏水凝胶。该3D打印丝素蛋白基温敏水凝胶可以实现药物负载，获得具有精确可控多孔结构的水凝胶并实现药物的可控释放。
Resumen de: CN120173754A
本申请公开了一种3D打印构建菌丝体活体材料并调控生长行为的方法，通过制备封装了真菌孢子的微凝胶颗粒，形成具有优异流变性能的双相微凝胶生物墨水；该墨水适用于挤出式3D打印，可支持真菌孢子的萌芽和菌丝网络的生长，实现菌丝体自生长行为在空间约束、营养浓度和基质刚度等关键因素上的精准调控。本申请通过设计构建自引导菌丝体生长通道结构，为工程化活体材料的设计与应用提供了创新解决方案，具有广阔的应用前景。
Resumen de: CN120168219A
本发明提供了一种晶状体固定标记器及其制作方法、设备，晶状体固定标记器包括手柄和与手柄连接的固定基座，手柄与固定基座通过错位方式连接，固定基座在远离手柄的一侧开设有凹口，凹口的两侧均设有用于标记晶状体角膜缘特定位置的凸起部，且凹口的两侧间设有具有呈弧形的平滑凹面，且设置于凹口的同一侧上的各凸起部位于同一直线上。本发明提出的方案通过将手柄与基座错位设置，有助于用户观察固定状况和标记位置，增加了手术操作的精准性，提高手术的成功率，凸起部能够能够精确标记晶状体角膜缘的多个特定位置，弧形的平滑凹面设计有助于引导晶状体的位置，能够减少与眼部的摩擦，避免损伤角膜或晶状体，提高手术的安全性和舒适性。
Resumen de: WO2024045916A1
The present application relates to the technical field of brace design, and relates to a brace modeling method, a device, a medium, and a brace manufacturing method. The brace modeling method comprises: obtaining a three-dimensional model of a target part of a limb; determining feature mark points of the three-dimensional model; determining brace modeling parameters of the three-dimensional model according to the feature mark points; and on the basis of the brace modeling parameters, generating brace file information corresponding to the target part, so that a brace can be manufactured later by using the brace file information. Thus, the convenience and accuracy of brace modeling can be improved, the personalized requirements of brace design are met, and the matching degree between the obtained brace model and the limb of a patient can be improved. Moreover, the problems due to the fact that brace file information designed by the existing automatic generation design processes can only be used for simple model processing and cannot be practically applied to complex brace design are solved, the design time of brace manufacturing can be effectively shortened, and the brace design costs can be reduced.
Resumen de: CN120168151A
本发明公开了一种弹性模量梯度桩核材料及其制备方法，和采用该材料制备得到的弹性模量梯度桩核。本发明的制备方法首先通过临床扫描患者桩道形态，制备出形态大小匹配的桩核修复系统，进而通过模拟天然牙齿的弹性模量梯度分布，利用增材制造工艺制备出具有仿生功能梯度桩核系统，可以改善桩、桩‑牙齿界面及牙齿部位的应力分布情况，有利于延长桩核修复患牙的寿命。
Resumen de: CN120168221A
本发明公开了一种用于将药物精准递送至圆窗龛的个性化辅助植入物，包括设置于外耳道的主结构；所述主结构的一个底面位于骨性外耳道中部，朝向鼓膜及中耳，另一个底面位于外耳道开口；所述主结构的侧面的形状轮廓与患者外耳道的解剖结构相适配并机械性固定连接；所述主结构的两个底面之间设有中空的直线的输送通道，且所述输送通道的延长线对准内耳结构的圆窗龛；所述主结构采用生物相容性柔性材料制造。本发明能够避免传统的内窥镜引导下经鼓膜注射给药依赖医生手动操作，存在个体操作差异、解剖复杂性影响以及药物流失风险的问题，并且能够广泛应用于药物输送、造影剂及局部麻醉剂注射、基因治疗、生物传感器或微电极植入等领域。
Resumen de: AU2023371660A1
Provided herein are medical devices and methods for treating bone fractures. The medical device comprises a body with a proximal end and a distal tip, housing a scaffold with a porous structure distributed in proximal and distal lattices. The device includes an upper lumen in fluid communication with a first opening at the proximal end, and a lower lumen in fluid communication with a second opening at the proximal end. The device is configured to support independent delivery of cement and cells to the lattices. In some embodiments, the device is a bone screw with a thickened head-neck junction, designed to reduce the likelihood of rod breakage during installation. The methods involve implanting the device into a patient's bone, providing an innovative approach to fracture treatment.
Resumen de: WO2025120338A1
Biodegradable 3D printed structure for bone augmentation (1) comprises an outer structure (100) and an inner structure (200) that are printed from polylactide (PLA), wherein the inner structure (200) is filled with a chitosan and hydroxyapatite gel and the outer structure (100) is coated with a chitosan and hydroxyapatite composite. The outer structure (100) has a tunnel-like shape resembling an elongated projection of the letter "U" rotated 180 degrees in depth. Implants made in the form of a biodegradable 3D-printed structure for bone augmentation as disclosed in the present invention can be adapted to each individual patient and each individual situation, which will optimize the dentist's time required for the procedure and treatment, and will also facilitate the recovery of the patient due to the reduction of the invasiveness of the procedure. This makes the entire procedure faster, simpler, and painless, but also financially acceptable for patients.
Resumen de: CN120174451A
本发明公开了一种3D打印钛合金复合涂层材料及其制备方法和应用，涉及钛合金材料技术领域。通过在3D打印钛合金基体上形成微弧氧化陶瓷涂层并原位生长Mn‑MOF材料，能够显著提高钛合金的生物相容性，该复合涂层不仅提高了3D打印钛合金基体的表面粗糙度，而且通过Mn的引入有效促进了细胞增殖和粘附，从而提高了钛合金在生物医用领域的应用潜力。
Resumen de: CN120168711A
本发明公开了一种墨水直写3D打印陶瓷材料及其制备方法和应用。所述制备方法包括步骤：制备得到氧化锆陶瓷浆料，所述氧化锆陶瓷浆料为粘弹性浆料，在剪切速率>10s‑1时，黏度＜100Pa·s，且浆料的屈服应力＞200Pa；按照预定的程序结构将所述氧化锆陶瓷浆料进行墨水直写3D打印，实现原位实时固化，得到三维陶瓷结构前体；将所述三维陶瓷结构前体进行烧结。本发明的制备方法通过优化氧化锆陶瓷浆料参数，经过墨水直写3D打印后，出料均匀，粘结强度好，烧结变形小，收缩率稳定，利于控制孔隙率，适用于打印不同填充比的陶瓷材料，便于模拟天然牙齿弹性模量梯度变化，得到更符合牙齿实际弹性模量分布的桩核修复系统。
Resumen de: WO2024110805A1
The invention relates to a curable composition for use in a process of treating a dental situation in the mouth of a patient, the curable composition comprising radiation-curable component(s), photo-initiator(s), the photo-initiator(s) exhibiting an absorption in the UV light region, and an absorption in the visible light region, the absorption in the UV light region being stronger than the absorption in the visible light region, optionally filler(s), optionally additive(s), the process comprising the steps of additive manufacturing a dental or orthodontic article layer-by-layer using radiation with a wavelength in the UV light region, attaching the dental or orthodontic article to a surface of hard dental tissue or a dental material, applying radiation with a wavelength in the visible light region to the dental or orthodontic article.
Resumen de: CN120168160A
本发明公开了一种多孔结构钽金属牙种植体及其加工方法，属于牙科口腔技术领域；包括包括纯钛实体部分和钽小梁部分；所述纯钛实体部分上设有自攻型螺纹；所述钽小梁部分为螺旋状结构；沿纯钛实体部分的自攻型螺纹设有用于嵌入钽小梁的螺旋槽；钽小梁部分位于对应的螺旋槽。本发明整体均匀的增加骨结合效果，减少骨结合时间，提高稳定性。
Resumen de: WO2025128987A1
Described are continuous manufacturing methods using 3D printing or any similar additive manufacturing technology to produce pharmaceutical ASDs. Manufacturing methods include preparing printing ink including API and polymeric carriers. The printing ink is accurately deposited onto a deposition surface by forming printing ink droplets by using an electromagnetic DoD 3D printing device to form an ASD printed product. The ASD printed product has improved solubility and bioavailability than the API in crystalline form.
Resumen de: US2025197789A1
A reinforcing and scaling construction for a bioprinted tissue model, which comprises a casing and sealing bioink, the casing comprising an inner module comprising a casing base (1) and a perforated cover (2), and an outer module comprising a container (3) comprising technological valves (5), an outer cover (4) and plugs (6) for technological valves (5). The invention also relates to a method for assembling the reinforcing and sealing construction.
Resumen de: WO2025127906A1
The present invention relates to 3D-printed anatomical models with flexible photopolymerisable coatings that allow the production of solid hollow models, which may be geometrically highly complex, with high anatomical fidelity and high optical translucency. The piece of the invention mainly acquires these advantageous technical features as a result of the use of coatings that can be photopolymerised by means of step-growth mechanisms or hybrid polymer reactions, as is achieved with thiol-ene chemistry, also called click chemistry or thiol-Michael additions, which may be mediated by free radicals or catalysts.
Resumen de: WO2025127247A1
A method for manufacturing a patient-customized wound dressing integrated with microneedles, and a patient-customized wound dressing integrated with microneedles, manufactured through same, are provided. A wound dressing is manufactured through 3D bioprinting by using a photopolymerizable biocompatible biodegradable bioink, and then microneedles are formed on the wound dressing through two-photon polymerization (2PP) printing by using the photopolymerizable biocompatible biodegradable bioink, and thus the patient-customized wound dressing integrated with microneedles is manufactured.
Resumen de: US2025197813A1
A method For manuFacturing a perFusable three-dimensional tissue model, containing therein a channel distributed across its entire structure, enabling the Flow oF Fluids, wherein bioprinting a vascular system with the extrusive method using bioink, the walls opening and closing the channel in its upper part being printed parallel to the channel axis, and bioprinting oF the model body with the extrusive method using bioink, the bioink For printing the body being diFFerent From the bioink used For bioprinting the vessels, placing the resulting system in an incubator, in a temperature in which bioink For printing the vascular system undergoes melt, removing the bioink, optionally, causing growth in the channel by means oF cells in a medium, wherein, the cross-section oF the channel being the same as the cross-section oF native vessels present in a living organism. The inventions relates to a bionic model with a perFusable system.
Resumen de: US2025195144A1
A system for mixed reality surgical simulation is provided. The system includes a simulator, an optical tracking system, an input device, a visualization screen, and a simulation workstation, wherein the simulation workstation renders an augmented view on the visualization screen.
Resumen de: US2025196403A1
A photocurable composition, contains a (meth)acrylic monomer component, and photopolymerization initiator, in a case in which a rectangular sheet-like test piece A1 with a length of 40 mm, a width of 10 mm, and a thickness of 1.0 mm is produced by photomodeling under conditions in which the photocurable composition is irradiated with visible light having a wavelength of 405 nm at an irradiation dose of 11 mJ/cm2 to form a cured layer A1 with a thickness of 50 μm, the cured layer A1 is stacked in a thickness direction thereof to form a rectangular sheet-like modeling product A1 with a length of 40 mm, a width of 10 mm, and a thickness of 1.0 mm, and the modeling product A1 is irradiated with ultraviolet rays having a wavelength of 365 nm at an irradiation dose of 3 J/cm2 to produce the test piece A1.
Resumen de: US2025195191A1
The present disclosure provides an apparatus for post-curing an article, as well as a system, methods, and post-cured articles. The apparatus includes a housing, a chamber disposed in the housing, at least two light emitting diodes (LEDs) disposed within the housing, and a user interface disposed on an exterior of the housing. The chamber is adaptable to each of an open, closed, and hermetically sealed configuration. The chamber includes a material transparent to actinic radiation and light from the LEDs enters the chamber from more than one direction. The user interface includes a display and program switches configured to adjust at least three operational parameters of the apparatus. The apparatus further includes a vacuum pump operatively coupled to the chamber. The system includes the apparatus and an article. An article includes layers of at least one photopolymerized crosslinked composition and a low extractable component content. A method of post-curing an article includes obtaining an article, placing the article in an apparatus, inputting a post-cure program or accessing a saved post-cure program through the user interface, and running the post-cure program. The post-cure program includes light intensity provided by a light source and length of time of light provided by the light source, plus a delay time between initiation of light provided by the light source and initiation of vacuum pulled by the vacuum pump and/or a delay time between initiation of vacuum pulled
Resumen de: US2025195208A1
The invention relates to an ear implant for improving or restoring the hearing ability in the event of defects in the area of the ossicles of the ear or posterior wall of the auditory canal, said implant consisting of lithium disilicate glass ceramic having a molar ratio of SiO2 to Li2O of 2 to 3, wherein the glass ceramic material being doped and stabilized with P2O5 and ZrO2, as well as a method for the production of the implant and the use of lithium disilicate glass ceramics in ear implants.
Resumen de: US2025195099A1
The invention relates to a method of manufacturing an inner tube for a surgical cutting device comprisinga. an outer tube having an outer tube head portion at a distal end of the outer tube;b. said outer tube head portion having an outer tube window; whereinc. the inner tube can be rotatably disposed in the outer tube;d. an inner tube head portion is provided at a distal end of the inner tube; whereine. at least one cutting edge is formed on the inner tube head portion, which cutting edge is moved out of an interior of the outer tube when the inner tube is rotated through the outer tube window and is moved back into the interior of the outer tube when the inner tube is further rotated through the outer tube window; the method comprising the following steps:f. providing an inner tube middle portion having a distal end;g. forming the inner tube head portion at the distal end of the inner tube middle portion by an additive manufacturing process to obtain the inner tube.
Resumen de: US2025196517A1
The present invention provides a printing mechanism for a medical monitoring device and a medical monitoring device. The printing mechanism comprises a movable frame assembly comprising a frame and a print paper drawer for holding the print papers, the print paper drawer being mounted on the frame to move along with the movable frame assembly, wherein a front end wall of the print paper drawer is formed as a curved wall comprising a first portion extending perpendicularly from a front end of a bottom plate of the print paper drawer and a second portion extending from the first portion and bending towards a rear end of the print paper drawer with respect to the first portion, and the second portion forms an anti-tilting surface for preventing the print papers from tilting. According to the printing mechanism for the medical monitoring device of the present invention, the end of the print papers contacting the anti-tilting surface does not slip and tilt during printing while the smoothness in feeding the print paper to the printing head is not affected.
Nº publicación: US2025195179A1 19/06/2025
Solicitante:
CUDETI SAGL [CH]
Cudeti SAGL
Resumen de: US2025195179A1
There is described a medical implant comprising: a bone engaging portion comprising: an outer portion comprising or consisting of a conformal lattice structure; an inner portion comprising a cavity or a lattice structure; a helical thread extending around and recessed into or protruding from an outer surface of said bone engaging portion, said helical thread being configured to facilitate screwing of said bone engaging portion into bone.
BOPI
Sede Electrónica
