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169
results.
Updated on
21/10/2025 [07:27:00]
Absstract of: US2025319145A1
The present invention relates to an anti-inflammatory extract of soil microorganisms or a fraction thereof, wherein the microorganisms comprise one or more selected from Chlorophyta, Xanthophyceae or Cyanobacteria. The invention further relates to compositions comprising two or more of Lyso-DGTS, p-Coumaric acid (ester-linked), oleamide, theophylline, or DGTS. The invention further relates to pharmaceutical compositions comprising the anti-inflammatory extract of soil microorganisms or a fraction thereof or a composition comprising two or more of Lyso-DGTS, p-Coumaric acid (ester-linked), oleamide, theophylline, or DGTS as an active ingredient. The invention further relates to an anti-inflammatory extract of soil microorganisms or a fraction thereof or a pharmaceutical composition comprising an anti-inflammatory extract of soil microorganisms or a fraction thereof or a composition comprising two or more of Lyso-DGTS, p-Coumaric acid (ester-linked), oleamide, theophylline, or DGTS as an active ingredient for use as a medicament, wherein the microorganisms comprise one or more selected from Chlorophyta, Xanthophyceae or Cyanobacteria. The invention further relates to compositions comprising an anti-inflammatory extract of soil microorganisms or a fraction thereof, wherein the microorganisms comprise one or more selected from Chlorophyta, Xanthophyceae or Cyanobacteria.
Absstract of: AU2025238093A1
A biofertiliser composition comprising a living microalgae component consisting of a live microalga of Chlorella spp. and a live microalga of Anabaena spp., wherein the ratio of Chlorella spp. to Anabaena spp. is from 1.0:0.8 to 1.0:1.2. ep b i o f e r t i l i s e r c o m p o s i t i o n c o m p r i s i n g a l i v i n g m i c r o a l g a e c o m p o n e n t c o n s i s t i n g o f a e p l i v e m i c r o a l g a o f h l o r e l l a s p p a n d a l i v e m i c r o a l g a o f n a b a e n a s p p , w h e r e i n t h e r a t i o o f h l o r e l l a s p p t o n a b a e n a s p p i s f r o m : t o :
Absstract of: AU2024242961A1
Provided is a method for producing ammonia comprising: preparing a modified cyanobacterium in which the proportion of heterocysts in cells constituting a nitrogen-fixing cyanobacterium is increased; and irradiating a mixture containing the modified cyanobacterium, a photocatalyst, and water with light in the presence of nitrogen.
Absstract of: WO2025217267A1
Methods for the fermentative production of O-phosphoserine, cysteate, or taurine in microbes or unicellular organisms that contain a serB mutation that either decreases serB expression, reduces the amount of the serB gene product or results in a serB gene product with low enzymatic activity. Genetic modifications of the O-phosphoserine, cysteate, or taurine and/or substrate biosynthetic pathways in unicellular organisms that include bacteria, algae, microalgae, diatoms, yeast, or fungi are disclosed. Also disclosed are fermentation and processing methods for the production of various O-phosphoserine-, cysteate-, or taurine-containing products and the use of the cells, fermentation broth or extracts that contain O-phosphoserine, cysteate, or taurine to produce products for use in food, feed, beverages, dietary and health supplements, cosmetics, personal care, pharmaceuticals, agricultural production, or surfactants.
Absstract of: WO2025210558A1
The present invention relates to a process for isolating Extracellular Vesicles (EV) secreted by microalgae (MEV - microalgae extracellular vesicle) cultured in basal and stress environment conditions namely pH, salinity, light, nutrient starvation, and temperature. Additionally, microalgae can be cultivated in thermal water classified as bicarbonate, sulphate, sulphide, chloride, or weakly mineralized trace metal. The present invention also relates to compositions comprising said MEV, which are useful to be applied to therapeutic, cosmetic, nutraceutical, phytopharmaceutical and medical including veterinary applications. The present invention lays in the technical domain of pharmaceuticals, medicine, cosmetics, nutraceutical, veterinary and research and development in cellular biology and appliances thereof.
Absstract of: GB2640110A
The present invention relates to the technical field of aquaculture effluent treatment, in particular to an apparatus for microalgae-microorganism synergistic treatment of aquaculture effluent. The apparatus comprises an aquaculture part; the aquaculture part is in communication with an effluent discharge part; the effluent discharge part is in communication with an effluent treatment part; and the effluent treatment part is in communication with the aquaculture part. The effluent discharge part comprises an effluent discharge pipe in communication with the aquaculture part; the end of the effluent discharge pipe away from the aquaculture part is in communication with the effluent treatment part; and an effluent discharge pump is arranged on the effluent discharge pipe. The effluent treatment part comprises a second housing; the bottom end of the second housing is in communication with the effluent discharge pipe; the top end of a side wall of the second housing is in communication with the aquaculture part; the interior of the second housing is provided with a plurality of flow guide plates; and microalgae are inoculated on outer side walls of the flow guide plates. In the present invention, microalgae and original microorganisms in aquaculture effluent form microalgae-microorganism symbionts, which can reduce carbon, reduce nitrogen and remove phosphorus synchronously and have few effects on aquaculture organisms, so that the quality of discharged water can be greatly impro
Absstract of: WO2025206966A1
The present invention refers to a biotechnological process for obtaining suspensions of biogenic nanoparticles of zerovalent selenium, which have a high stability, and which have agronomic functions specific to plant biostimulants, that are amplified as a result of the formation of a biocorona which includes bioactive molecules from the biotechnological system wherein these selenium nanoparticles were formed. The biotechnological process involves the biosynthesis of selenium nanoparticles by the consortium of microalgae, Nannochloris sp. 424-1, deposited under CCAP number 251/10 in the Culture Collection of Algae and Protozoa (CCAP), and yeasts, Rhodotorula mucilaginosa TazRr, deposited under DSM number 34804, at the Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures, to promote the formation of suspensions of stable selenium nanoparticles. The process also includes separation and concentration steps by micro- and ultrafiltration on ceramic membranes.
Absstract of: EP4620529A2
A composition comprising a eukaryotic microalgae or an extract thereof may be for use in the treatment of a viral disease, e.g. coronavirus, and for use as an inhibitor of the binding of Spike protein receptor binding domain (RBD) to Angiotensin-Converting Enzyme 2 (ACE2). A compound derivable from eukaryotic microalgae may also be for use in the treatment of a viral disease. In turn, a eukaryotic microalgae may be used as an antiviral agent.
Absstract of: WO2024105258A1
The invention relates to a method for the preparation of microalgal for use as a food-grade ingredient without the need of any further purification or separation step and resulting products therefrom.
Absstract of: WO2025191569A1
Provided by the present disclosure is an aquatic cultivation system (mic-RAS), method of cultivation and microalgae obtainable thereby. The system comprises an aquatic cultivating tank comprising treated media inlet and effluent outlet; a photo-membrane bioreactor (PMBR) comprising a membrane having selective permeability, a PMBR inlet and a PMBR outlet; and fluid communication lines for continuous circulating effluent from the effluent outlet into the PMBR and treated media from the PMBR outlet into the aquatic cultivating tank. The method comprises cultivating aquatic organisms in an aquatic cultivating media within a cultivating tank; cultivating microalgae in an effluent media within a PMBR, the PMBR comprising membrane having selective permeability, submerged within the effluent media, the cultivating of the microalgae comprises: illuminating the microalgae; and circulating effluent from the cultivating tank into the PMBR and treated media from the PMBR into the cultivating tank. Further there is provided a microalgae, preferably obtained or obtainable by the system and/or method.
Absstract of: PL447926A1
Przedmiotem zgłoszenia jest sposób wytwarzania pożywki do hodowli sinic z biomasy bakteryjnej po produkcji polihydroksyalkanianów. Wynalazek znajduje zastosowanie w hodowli zwłaszcza Arthrospira platensis.
Absstract of: US2025277228A1
Monoclonal antibodies represent the most rapidly growing category of the recombinant therapeutic protein pipeline, with more than 85% of the therapeutic indications. The present invention proposes novel vectors that have been optimized so as to produce high levels of monoclonal antibodies when transfected in the microalgae Phaeodactylum tricornutum, as well as optimized culture conditions of said microalgae cells. Altogether, the present invention provides new systems for producing high amounts of monoclonal antibodies, functional fragments or derivatives thereof, in microalgae.
Absstract of: AU2024387147A1
The present invention relates to a glass noodles wastewater treatment process based on microalgae, belonging to the technical field of microbial wastewater treatment. Chlorella sorokiniana NZ1 and Monoraphidium sp. NZ4 are selected. An analysis of experiment results shows that when Chlorella sorokiniana NZ1 and Monoraphidium sp. NZ4 are subjected to mixed culturing, the biomass of both in the wastewater reaches the highest level. At the same time, the removal rates of water quality indicators also exhibit the most significant improvement; specifically, the removal rates of COD, TN, ammonia nitrogen, and TP can respectively reach 83.4%, 91.19%, 81.51%, and 78.71%. Thus, it can be concluded that subjecting the algal strains NZ1 and NZ4 to mixed culturing is the most effective glass noodles wastewater treatment method.
Absstract of: WO2025181256A1
The invention relates to modified cyanobacterial strains comprising one or more modifications to enhance the rate of carbon dioxide fixation relative to a cyanobacterial strain which does not comprise said modifications.
Absstract of: WO2024088808A1
Provided are compositions containing microalgae extracellular vesicles (MEVs) formulated for intranasal delivery, whereby, upon intranasal administration the MEVs traffic through specific routes following intranasal administration to specific regions in the brain via the olfactory nerve and throughout the lateral olfactory tract (LOT) to interconnected brain regions. The MEVs traffic via neuronal axonal transport. The MEVs have the ability to cross-over synapses including: (i) the synapses between the olfactory sensory neurons (OSN) and the mitral/tufted neurons; (ii) the synapses between the mitral/tufted neurons and the local neurons in the various brain regions colonized by the lateral olfactory tract (LOT); and (iii) the synapses between the neurons in the brain regions colonized by the LOT and neurons from the frontal cortex, the hippocampus, the thalamus, and the hypothalamus. The compositions contain extracellular vesicles from microalgae (MEVs) that are loaded with bioactive cargo for treating, detecting, diagnosing, or monitoring a disease, disorder, or condition of the brain or involving the brain, particularly providing neuronal delivery of the cargo. The compositions and methods have a variety of applications as therapeutics and diagnostics for treating, diagnosing, and monitoring a disease, disorder, or condition of the brain or involving the brain. The compositions can be used in methods and uses for treating cancers involving the brain, and can be used, for exa
Absstract of: GB2638687A
A modified cyanobacterium comprising one or more genetic modifications for improving expression of aromatic amino acids through overexpression of shikimate pathway to enhance the rate of carbon dioxide fixation relative to a cyanobacterium which does not comprise said genetic modifications. Also disclosed is use of AroF D174N and/or TesA for increasing the rate of carbon dioxide fixation by a modified cyanobacterium. The cyanobacterium can be Synechococcus sp., e.g. Synechococcus 11901 or a variant thereof. The modified cyanobacterium can comprise one or more genetic modifications to over-express shikimate kinase (SK) in the modified cyanobacterium.
Absstract of: CN120551165A
The invention provides a waste frozen product harmless resource regeneration method based on microalgae synergistic fermentation, and belongs to the technical field of waste frozen product harmless treatment. The preparation process comprises the following steps: pretreatment of waste frozen products; carrying out synergistic fermentation on the pretreated frozen microalgae; and directionally preparing the product. According to the method, in the pretreatment stage, ozone water is adopted for sterilization, citric acid is used for adjusting the pH value to be acidic, synergistic fermentation of bacillus and lactic acid bacteria is combined, harmless treatment is achieved, multi-stage resource utilization is achieved based on microalgae synergistic fermentation, and the additional value is increased.
Absstract of: CN120554161A
The invention provides a charcoal-based microalgae fertilizer as well as a preparation method and application thereof, the method adopts a mode of co-fermentation of charcoal and microalgae to fix microalgae on charcoal, and co-fermentation is performed to prepare the charcoal-based microalgae fertilizer. The biochar-based microalgae fertilizer can significantly improve the crop yield, increase the chlorophyll content of crops, promote healthy growth of plants, optimize the pH value of soil, enhance the water and fertilizer retention capacity of soil, and significantly improve the soil nutrients and soil enzyme activity, and has significant advantages in the aspects of nutrition supply, soil health, environmental protection, crop quality improvement and the like. The biochar-based microalgae fertilizer has two forms of liquid and dry powder, can be flexibly used according to a specific agricultural production mode, has the advantages of easily available raw materials and simple preparation, is a sustainable fertilizer source, can comprehensively improve the soil fertility and the crop stress resistance, reduces the dependence on chemical fertilizers, and reduces the environmental pollution problem in agricultural production.
Absstract of: CN120555194A
The invention belongs to the technical field of biology, and relates to a synechococcus resistant to high-concentration carbon dioxide and a preparation method and application of the synechococcus resistant to high-concentration carbon dioxide, and the synechococcus resistant to high-concentration carbon dioxide comprises CRISPR/dCas9 plasmids, gRNA plasmids and knockout omega plasmids. According to the invention, PEPC is transcriptionally activated through a CRISPR/dCas9 system, so that PCC7942 can grow under the condition of high-concentration CO2. Besides, the fusion between the omega subunit of RNAP and a Cas9 nuclease mutant directionally combined with an upstream promoter region can realize programmable transcriptional activation, and the growth and carbon sequestration efficiency of microalgae under high-concentration CO2 is improved by knocking out the omega subunit and utilizing a CRISPR/dCas9 transcriptional regulation system to optimize a photosynthetic carbon sequestration pathway of the microalgae.
Absstract of: CN120555143A
The invention discloses a closed double-layer stirring type photobioreactor, and relates to the technical field of microalgae culture. A double-layer special-shaped paddle combination is formed through the composite design of a four-straight-blade overall open turbine type (SK) and a three-blade left-handed push type spiral stirring paddle (TXL), paddle combination optimization is formed through the cooperative flow field design of the TXL paddle (lower layer) and the SK paddle (upper layer), axial-radial flow coupling is achieved, and the material exchange rate between gas and liquid is increased; according to the combined design of the double-layer special-shaped paddles, the proportion of a high-shear area is reduced to be lower than 12% through a wide-area low-strength shear mode of the TXL paddles, the shear stress is greatly reduced, and the problem that the shear stress is too high is solved; a dynamic rotating speed strategy is convenient to implement, and the mass transfer efficiency and the cell activity are both considered by adjusting the rotating speed in stages.
Absstract of: US2025270148A1
A method for processing animal products, in particular products from poultry farming, includes: a) chemically treating by placing collected waste in contact with an ammonia-based buffer with a pH of at least 8; b) heating the material resulting from step a) in a humid medium to a temperature of at least 70° C.; c) separating the organic matter and inorganic matter in the presence of water from the material resulting from step b), then separated collection of (i) the liquid fraction having the inorganic matter, and (ii) the solid fraction having the organic matter; and d) adding the liquid fraction resulting from step c (ii), having the inorganic matter, in a basin filled with water held in a controlled manner at a setpoint temperature ranging from 20° C. to 42° C., preferably from 28° C. to 35° C., in which a protein-rich plant or bacterium is cultivated, in particular microalgae or cyanobacteria, preferably spirulina.
Absstract of: WO2025176847A1
Provided are compositions containing microalgae extracellular vesicles (MEVs) formulated for administration to the eye for treatment of diseases, disorders, and conditions of the eye, particularly for diseases, disorders, and conditions that involve tissues and cells in the back of the eye, which generally cannot be treated with eyedrops. Upon administration to the eye, the MEVs deliver therapeutics to tissues that include the choroid, retinal pigment epithelium cells, and photoreceptor cells. The compositions contain extracellular vesicles from microalgae (MEVs) that are loaded with bioactive cargo for treating or diagnosing or monitoring a disease, disorder, or condition of the eye or involving the eye. Methods of treatment of diseases, disorders, and conditions of the eye are provided.
Absstract of: US2025270486A1
An assembly, methods, and network for farming and culturing green microalgae (Haematococcus pluvialis) are disclosed, comprising: a mechanical support framework; a plurality of cultivation pouches, mechanically coupled to the mechanical support framework, having arrays of cultivation pouches where green microalgae (H. pluvialis) are cultured and harvested; a plurality of light emitting diodes (LEDs), mechanically coupled and supported by the mechanical support framework and arranged in between two of any adjacent arrays of cultivation pouches, operable to provide a predetermined light intensities to each of the cultivation pouches; and an air and gas supply and distribution unit, mechanically coupled and supported by the mechanical support framework, operable to supply predetermined amounts of air and carbon dioxide (CO2) to each of the green microalgae pouches.
Absstract of: WO2025176843A1
Provided are gene therapy vectors designated MEV-GTVs, which are MEVs that contain an ITR-containing plasmid (also referred to as a minigene plasmid) that comprises Inverted Terminal Repeats (ITRs), such as viral ITRs, and nucleic acid encoding a product of interest, and optionally regulatory sequences. The ITRs serve to circularize the minigene plasmid. The plasmids do not contain additional viral components, so that resulting DNA is not encapsulated in a viral capsid or envelop and is not replicated by viral genes. The plasmids can be inserted into bacterial plasmids for propagation.
Nº publicación: CN120530912A 26/08/2025
Applicant:
YANTAI INSTITUTE OF COASTAL ZONE RES CHINESE ACADEMY OF SCIENCES
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Absstract of: CN120530912A
The invention discloses an oyster biological reaction system construction method, a colored oyster feeding method and an oyster product. The oyster biological reaction system construction method comprises the following steps: screening out an optimal filter feeding environment condition of oysters; screening the microalgae filtering efficiency of the oysters under the optimal filtering environment condition, and determining the optimal filtering concentration of the oysters to the microalgae; the oysters are placed under the optimal filter feeding environment condition, and different types of microalgae are selected to be densely fed for a short time at the optimal filter feeding concentration; the method comprises the following steps: carrying out stage division on interception, absorption and conversion conditions of microalgae in oysters from a time scale by taking content change of symbolic components in the oysters and nutritional components as indexes, and constructing oyster biological reaction systems in different stages. By means of the method, the oysters can be fed within a short time, rapid nutrition conversion is achieved, the pigment level of edible parts of the oysters is improved, the quality of the oysters is improved, and meanwhile the accurate nutrition enrichment type colored oysters can be created.
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