Absstract of: CN221556906U
本实用新型公开了一种打印终端,该打印终端旨在解决现有技术下取件的多为病人,因此接触控制键容易引发病毒交叉感染,从而会导致疾病的发生和加重的技术问题。该打印终端包括终端机体、显示屏、控制键和出纸口,终端机体的表面嵌合安装有显示屏,终端机体的内壁嵌合安装有控制键,终端机体的侧表面开设有出纸口,终端机体的内部设置有消毒机构,终端机体的侧表面设置有粉碎机构。该打印终端,首先消毒液仓内部的消毒液可以经喷头喷洒在控制键的表面,接着控制伸缩杆进行延伸,伸缩杆延伸可以通过清洁支架带动清洁海绵横向运动,清洁海绵横向运动可以吸收控制键表面消毒液滴,从而可以起到消毒的作用,这样可以降低病毒交叉感染的发生。
Absstract of: CN118512659A
本发明公开了一种管状细胞外基质纤维支架及其制备方法与应用,属于医用材料技术领域,本发明利用3D打印结合编织方法制备得到管状细胞外基质纤维支架后进行抗凝修饰,即得到所述管状细胞外基质纤维支架。同时公开了通过上述制备方法制备得到的管状细胞外基质纤维支架及其在制备组织修复支架材料中的应用。本发明通过多巴胺将管状细胞外基质纤维支架修饰上抗凝药物水蛭素,使得人工血管具有持久的抗凝活性,可以抑制血小板粘附活性,提高血液相容性,促进内膜再生,提升长期通畅率。
Absstract of: AU2024200699A1
Embodiments of the disclosure include compositions and methods for providing an effective amount of activated or unactivated single-cell or spheroid fibroblasts, exosomes from fibroblasts, lysate from fibroblasts, apoptotic bodies from fibroblasts, and/or fibroblast-related products that are comprised in and/or on a substrate, such as a synthetic polymer or biopolymer scaffolding or biologic mesh, thereby generating a material to cover at least one wound and/or at least one burn of an individual.
Absstract of: GEP20237562B
The invention concerns a detergent-free decellularized dECM preparation method, a detergent-free decellularized dECM in a powder form and in a liquid form, a method of preparation of a primary bioink, the primary bioink, a method of preparation of a vascular bioink, the vascular bioink, a three dimensional structure comprising the primary bioink and/or the vascular bioink and a method of preparation of the three-dimensional structure. s
Absstract of: CN221540668U
本实用新型公开了一种种植假牙的3D打印装置,其包括装置底座,所述装置底座的内部固定连接有操控屏,所述装置底座的上表面固定连接有固定框,所述固定框的外部转动连接有保护盖,所述固定框的内部设置有打印设备,所述固定框的内部设置有打印台组件。通过上述结构,通过转动保护盖可将固定框的整个面全部打开,方便了操作人员将模型拿取出来,降低了操作难度,同时,可将模型与圆轨、打印台本体和卡块整体拿出,进而避免了在装置内对模型与打印台本体进行分离,降低了模型打印的失败率,提高了生产效率,转动组件在方便了工作人员查看成品,同时也可以很好地适应打印台本体等部件的安装与分离,提高了装置组装操作的便捷性。
Absstract of: CN118490329A
本发明属于医疗器械领域,涉及一种可术中调整的椎弓根钉导板,包括横跨棘突的导板本体,导板本体端部固设有用于与脊椎骨面贴合的定位板,导板本体上设置有与规划置钉方向平行的导向柱,定位板上与规划置钉点相对应的位置开设有导向槽,本发明还涉及一种椎弓根钉置钉前处理方法,包括导板设计和制作、术前准备、置钉、二次调整的步骤。本发明通过半开放式的定位方式,使定位具备了一定的自由度和灵活度,术中可以进行二次调整和定位,提高了置钉的精准性,且便于术中导板的取出,同时节省了耗材成本,本发明的可术中调整的椎弓根钉导板适用于椎弓根钉内固定术中椎弓根钉的定位,本发明的椎弓根钉置钉前处理方法,适用于脊柱外科疾病的手术治疗。
Absstract of: CN118490877A
本发明涉及一种基于植物蛋白的生物打印墨水及其制备方法和应用,包括以下步骤:步骤1、将不可溶的植物蛋白转化为水溶性植物蛋白;步骤2、水溶性植物蛋白改性制得可光固化植物蛋白;步骤3、将可光固化植物蛋白制备成生物打印墨水或凝胶。本发明通过pH转变处理、析出、改性、纯化、冷冻干燥等系列步骤制备了可光固化植物蛋白。物理化学测试结果表明,该植物蛋白生物墨水水凝胶具有良好的流变性能、力学性能、溶胀率和降解率。该生物墨水具有良好的体外生物相容性,无免疫原性。通过优化相关打印参数,可成功实现对复杂形状的打印。
Absstract of: CN118490886A
本发明公开了一种含血管的梯度骨支架及其一体化制备方法。该方法包括:将光引发剂加入纯水中得到溶剂,其中光引发剂和纯水的质量体积比为0.1%g/ml;将甲基丙烯酸酯化明胶、纳米羟基磷灰石和聚乙二醇二甲基丙烯酸酯,加入溶剂中配制A溶液,其中甲基丙烯酸酯化明胶和溶剂的质量百分比为10%g/ml,纳米羟基磷灰石和溶剂的质量百分比为1~3%g/ml,聚乙二醇二甲基丙烯酸酯和溶剂的体积比为20~40%ml/ml;将海藻酸钠加入去纯水中得到B溶液,其中海藻酸钠和纯水的质量体积比为4%g/ml;使用同轴打印技术将得到的V溶液制备成血管支架;将血管支架放在打印平台上,使用A溶液打印骨支架后光固化得到含血管的梯度骨支架。通过本发明的制备方法,可实现对骨组织缺损的再生。
Absstract of: CN118490420A
本发明公开了一种3D打印个性化组配式支撑假体,涉及医用假体技术领域。该3D打印个性化组配式支撑假体包括第一支撑体和第二支撑体,其中,第一支撑体由3D打印而成,设置有第一装配面;第二支撑体由3D打印而成,设置有第二装配面;第一装配面和第二装配面的形状轮廓匹配,第一支撑体和第二支撑体通过第一装配面和第二装配面抵接至一起,且第一支撑体和第二支撑体装配至一起后的外轮廓与骨缺损区域的轮廓匹配。本发明提供的3D打印个性化组配式支撑假体能够与骨缺损的轮廓较为精确的匹配,并且在安装过程中更加便捷。
Absstract of: CN118490383A
本发明公开了一种辅助贴面、微贴面和嵌体就位的数字化导板制作方法,属于口腔微创和美学修复技术领域,包括以下步骤:采用三维口腔扫描技术对患者牙齿进行全面扫描,得到三维扫描数据;基于三维扫描数据,重建三维模型,并通过计算机辅助设计CAD对导板进行个性化设计,得到数字化导板;通过3D打印技术打印数字化导板,并对打印数字化导板进行后处理,得到用于辅助贴面、微贴面和嵌体就位的数字化导板。本发明解决了传统方法修复件就位精确性不足、治疗过程复杂耗时以及患者体验不佳的问题。
Absstract of: CN221534135U
本申请涉及义齿技术领域,提供了一种基于3D打印的义齿,包括义齿基座和义齿本体,所述义齿本体可拆卸安装于所述义齿基座,所述义齿基座设置有连接部,所述连接部开设有螺纹槽,所述义齿基座底部开设有螺纹孔,所述螺纹孔与所述螺纹槽内共同穿设有螺栓。本申请的一种基于3D打印的义齿,螺栓能够将义齿本体和义齿基座可拆卸连接,在长时间使用义齿后,能够将义齿本体拆卸进行清洗,减少相邻的义齿本体之间留有食物残渣的情况。
Absstract of: CN118490887A
本发明公开一种3D打印抗菌皮肤组织工程支架的制备方法,包括:将光引发剂与乙酸加入到去离子水中,得到溶剂;其中,光引发剂和去离子水的质量体积比为0.1%g/ml,乙酸和去离子水的体积比为2%;称取甲基丙烯酸酯化明胶和壳聚糖,加入溶剂中,配制GelMA/壳聚糖溶液,其中,甲基丙烯酸酯化明胶和溶剂的质量百分比为0.07~0.12g/ml,壳聚糖和溶剂的质量百分比为0.01~0.04g/ml;将得到的GelMA/壳聚糖溶液放入3D打印机进行3D打印,在打印过程利用紫外光灯固化GelMA/壳聚糖溶液,得到原始支架;将原始支架放入pH为7.4的1X磷酸盐缓冲溶液中,然后冲洗、冷冻干燥,得到3D打印抗菌皮肤组织工程支架。本发明的制备工艺简单,且得到的支架使皮肤缺损处可实现大面积皮肤再生。
Absstract of: CN118490888A
本发明公开了适用于体积生物打印的低浓度丝素蛋白/甲基丙烯酰化明胶生物墨水及制备方法和应用。低浓度丝素蛋白/甲基丙烯酰化明胶生物墨水包含:甲基丙烯酰化明胶、丝素蛋白、钌吡啶络合物/硫酸钠引发剂和溶剂;所述丝素蛋白的质量百分比为0.5~1.25%;所述甲基丙烯酰化明胶的质量百分比为0.6~20%。本发明提供的低浓度丝素蛋白/甲基丙烯酰化明胶生物墨水,在采用低浓度丝素蛋白的前提下,选用甲基丙烯酰化明胶并搭配特定的光引发剂,使得低浓度的丝素蛋白在体积打印中不发生晃动和沉降,从而得到更好打印分辨率和打印保真度的3D打印制品;此外,低浓度的生物墨水更有助于细胞的迁移和增殖。
Absstract of: CN118492403A
本发明属于钛合金零件制造技术领域,公开了一种选区激光熔化成型及热处理制备钛合金零件的方法,包括以下步骤:将钛合金粉末经干燥、选区激光熔化成型后得到成形钛合金零件,再进行热处理,随炉冷却,即得成品钛合金零件,热处理条件为940~980℃保温1~2h。本发明经过调试得到的工艺参数使得实际激光能量密度为102.6J/mm3,使得零件的体致密度达到97%以上,孔洞较少,可以应用于科研等后续性能测试实验。热处理后的选区激光熔化成型的TC4钛合金零件,其显微组织恢复到了α+β双相组织,提升了塑性,达到强度与塑性的较佳匹配,可以扩大其在工业中的应用。
Absstract of: CN118496523A
本发明涉及一种3D打印水凝胶及其制备方法和应用,本发明的水凝胶的制备是通过没食子酸改性明胶,与甲基丙烯化明胶采用3D生物打印的方式构筑。本发明的水凝胶在促进伤口愈合的同时,还具有粘附性好、抗炎抗氧化等多功能特性,同时满足异性伤口的应用需求,能够为伤口修复等生物应用领域提供更高的实用性。
Absstract of: CN221534278U
本实用新型涉及一种3D打印的足踝支具,包括本体和至少两个连接件,至少两个连接件设置于本体上,足踝支具包括通风夹层,通风夹层的形状与本体的形状相同,通风夹层包括第一垫层、第二垫层和多个支撑隔层,第一垫层和第二垫层面向本体依次设置,多个支撑隔层呈间隔设置于第一垫层与第二垫层之间,第一垫层的截面呈蜂窝状,各相邻的两个支撑隔层与第一垫层和第二垫层之间形成一条空气流道。本申请可以降低足部环境的问题,避免产生大量的汗液而造成足部潮湿,从而防止细菌滋生。
Absstract of: CN118490880A
本发明提供一种定制化仿生人工骨及其制备方法和应用。该人工骨基于临床影像数据进行三维建模,实现与骨缺损部位解剖形态的精准吻合。微观结构上,采用仿生学原理设计仿天然骨小梁互穿微孔结构,并引入孔隙率渐变以模拟天然骨骼的梯度分布。材料上,该人工骨对天然骨进行组分仿生,其主要成分为羟基磷灰石矿物,并且通过引入微量元素锰进一步增强其功能特性。3D打印成型的人工骨产品可进一步进行性质优化,通过在人工骨支架表面涂覆可控比例的高分子材料和重组人源化胶原蛋白复合涂层,可提升定制化仿生人工骨的强度、韧性及生物活性。本发明提供的仿生人工骨实现了精准定制及多种功能特性的融合,可促进骨缺损的快速修复,提高患者的生活质量。
Absstract of: WO2024165390A1
The invention relates to a method for additive manufacturing of a microstructure (10) for selective transmission of X-ray or gamma-ray radiation. The method includes depositing (110) a layer of powder on a build plate or on a layer from at least one previous manufacturing step on the build plate, wherein the layer of powder comprises a high-Z material powder. Furthermore, the method includes selectively melting (120) and solidifying the powder to form septa wall structures (20) by scanning an electron beam in a spot sequence on the layer of powder to sequentially expose a plurality of spots (40) on the layer of powder to an electron beam spot. A size of the electron beam spot is at most 150 μm in diameter, preferably at most 75 μm in diameter, and more preferably at most 50 pm in diameter. The high-Z material powder comprises a high-Z material having an atomic number Z of at least 40, and preferably at least 70. The invention also relates to a microstructure for selective transmission of X-ray or gamma-ray radiation, which microstructure has been obtained by the method, and to an imaging component comprising such microstructures. The invention also relates to a method for manufacturing an imaging component.
Absstract of: US2024270893A1
The present disclosure provides an orthodontic article including the reaction product of the polymerizable composition. Further, the present disclosure provides polymerizable compositions and methods of making an orthodontic article. The method includes obtaining a polymerizable composition and selectively curing the polymerizable composition to form an orthodontic article. Further, methods are provided, including receiving, by a manufacturing device having one or more processors, a digital object comprising data specifying an orthodontic article; and generating, with the manufacturing device by an additive manufacturing process, the orthodontic article based on the digital object. A system is also provided, including a display that displays a 3D model of an orthodontic article; and one or more processors that, in response to the 3D model selected by a user, cause a 3D printer to create a physical object of an orthodontic article.
Absstract of: WO2024168342A2
The present invention is directed to a novel 3D printed prosthetic sockets having one or more internally positioned support struts configured to counter the structural instability at the distal ends of the socket and prevent undesired sheering forces that can result structural failure of the socket.
Absstract of: WO2024167888A1
Embodiments of the disclosure include compositions and methods for providing an effective amount of activated or unactivated single-cell or spheroid fibroblasts, exosomes from fibroblasts, lysate from fibroblasts, apoptotic bodies from fibroblasts, and/or fibroblast-related products that are comprised in and/or on a substrate, such as a synthetic polymer or biopolymer scaffolding or biologic mesh, thereby generating a material to cover at least one wound and/or at least one burn of an individual.
Absstract of: WO2024166113A1
A method for generating reinforced engineered cellularized construct, which utilizes a biocompatible small-molecule reinforcing agent that do not affect the viability of the cells, a reinforced engineered cellularized construct obtained thereby and used the engineered cellularized construct are provided.
Absstract of: WO2024166632A1
The present invention provides a curable composition for three-dimensional stereolithography, the curable composition being used in a vat photopolymerization method and containing 100 parts by mass of a polymerizable monomer component (A), 40 parts by mass to 400 parts by mass of an inorganic filler (B) that is composed of a single kind or plural kinds of inorganic particulate matter, and 0.01 part by mass to 5 parts by mass of a photopolymerization initiator (C), wherein: 80% or more of all primary particles that constitute the inorganic filler (B) have a particle diameter of 0.05 µm to 5.0 µm; and a sample, which is formed of this curable composition for three-dimensional stereolithography and has a thickness of 0.5 mm, has a transmittance of 1.00% to 50.00% with respect to activation light. The present invention also provides a method for producing this curable composition for three-dimensional stereolithography. The present invention also provides a method for producing a three-dimensional stereolithographic model and a method for producing a dental restoration, each using this curable composition for three-dimensional stereolithography.
Absstract of: WO2024168243A1
Container systems including a syringe for containing bioink and for providing container closure integrity through cryogenic storage and warming are described. The syringe includes a barrel and a stopper that seals a proximal opening of the syringe. The syringe also includes a cap that is removably connected to a connector of the syringe at a distal end of the syringe and that seals a distal opening of the syringe. The syringe includes a piston within the barrel that can be spaced apart from the stopper when the barrel is filled with the bioink. The stopper and the cap can respectively seal the proximal and distal opening throughout a temperature range of between -196°C and 37°C.
Nº publicación: WO2024166068A1 15/08/2024
Applicant:
MANDIBLE GUIDE B V [BE]
MANDIBLE GUIDE B.V
Absstract of: WO2024166068A1
Device for widening a patient's palate comprising at least two supports (2, 3) which are connected to each other via an expansion module (6), wherein the expansion module (6) includes two members (7, 8) which can be moved relative to each other and which are connected to one another via an expansion screw (9), such that these members (7, 8) are moved relative to each other in the axial direction (11) of said expansion screw (9). Each of said members (7, 8) connects to one of said supports (2, 3). These supports (2, 3) each have a receiver element (14, 15) in which a respective member (7, 8) of said members (7, 8) of the expansion module (6) should extend at least partially.