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194
results.
Updated on
19/06/2025 [07:28:00]
Absstract of: AU2023323651A1
Provided is an implantable tissue scaffold comprising a mixture of a biocompatible organic polymer and chitin, wherein the chitin is embedded in the biocompatible organic polymer. Also provided is a composition for 3D printing, the composition comprising at least one biocompatible organic polymer and chitin that may be partially deacetylated, wherein the chitin is embedded within the biocompatible organic polymer. Further provided is a method of promoting tissue formation, comprising implanting a tissue scaffold comprising a mixture of a biocompatible organic polymer and chitin at a site in need of regenerative bone tissue formation.
Absstract of: WO2024033402A1
The invention relates to a maxillary modeller (2) intended to be worn, in a service position, on a dental arch of a user in order to modify the shape of the palate, the maxillary modeller being one-piece and removable and comprising: - a central palatal portion (22) configured to be in contact with the user's palate when the maxillary modeller is in the service position; and - a first and a second dental portion (24; 26) each comprising at least one, preferably multiple cavities configured to receive teeth of the user when the maxillary modeller is in the service position, the first and second dental portions extending on either side of the central palatal portion, the central palatal portion being configured so as to exert on the palate, in the service position, forces suitable for modifying the shape thereof.
Absstract of: CN222983250U
本实用新型公开了一种用于耳朵术后形态保持的支撑件，包括：内贴合层，外层桁架，所述外层桁架呈罩体形状，所述外层桁架的一侧边缘与所述内贴合层连接；支撑单元，所述支撑单元的数量为多个，所述支撑单元为弹性部件，所述支撑单元设置在所述内贴合层和所述外层桁架之间，所述支撑单元的一端与所述内贴合层连接，所述外层桁架的内侧与所述支撑单元的另一端连接，本实用新型可以提升保持器的舒适性以及支撑强度。
Absstract of: CN120154756A
本发明公开了一种用于修复骨缺损的DAT‑海藻酸钠3D多孔支架、制备方法及应用，本发明提供的DAT‑海藻酸钠3D多孔支架展现了良好的生物学性能和成骨诱导能力，在骨缺损修复中的应用潜力巨大。
Absstract of: AT527771A1
Es wird ein Helm (1) zur nicht-invasiven Hirnstimulation mit einem auf eine Kopfaufnahme (2) gerichteten Stimulationseinheit (3) beschrieben. Um eine präzise Bestrahlung eines individuell bestimmbaren Stimulationsbereichs zu ermöglichen und trotzdem dem Probanden eine gewisse Bewegungsfreiheit zu erlauben wird eine durch eine zur Kopfaufnahme (1) hin offene Absaugöffnung (4) vorgeschlagen, die mit einem außerhalb der Kopfaufnahme (2) angeordneten Unterdruckanschluss (6) strömungsverbunden ist.
Absstract of: CN120131256A
本发明公开了组织工程与再生医学技术领域的一种有支撑富弹性和防逆流功能的组织工程泪道，包括由脱细胞气管基质材料构成的泪道管主体，泪道管主体外表面外覆有外螺旋加固层，外螺旋加固层表面包裹有生物羊膜，泪道管主体的中部设有若干特斯拉阀结构，底部设有防逆流瓣膜。本发明采用脱细胞气管、生物羊膜、3D打印聚氨酯为支架构建组织工程泪道，并将特斯拉阀结构和防逆流瓣膜应用到组织工程泪道，从而保持泪管弹性且防止泪液和鼻腔分泌物及气体逆流。
Absstract of: CN120133517A
本申请属于合金材料技术领域，尤其涉及钛合金粉末材料、钛合金及其制备方法、应用。该钛合金粉末材料包括纳米Fe颗粒、纳米TiO2颗粒和Ti颗粒，其中纳米Fe颗粒、纳米TiO2颗粒分布在Ti颗粒的表面。该钛合金粉末材料中的Fe和TiO2以纳米颗粒的形式存在，并分布在Ti颗粒的表面，这样的分布有利于提高Fe元素和O元素的分布均匀性，缓解元素偏析形成有害力学性能的β‑fleck问题，进而改善钛合金的力学性能均匀性。
Absstract of: CN120132062A
本发明属于生物医学工程与增材制造交叉领域，具体涉及一种3D打印超材料压电型骨缺损修复支架，所述支架的孔隙结构由数学表达式定义的Gyroid、SchwarzP和Diamond三种极小曲面单元复合构成；所述支架的孔隙率为30％‑70％，孔径范围为0.1‑1mm；所述支架的材料为由聚偏氟乙烯、聚乳酸及钛酸钡组成的压电复合材料，所述压电复合材料按质量百分比如下：聚偏氟乙烯(PVDF)30％‑55％，聚乳酸(PLA)20％‑45％，钛酸钡(BaTiO3)10％‑25％，且各组分的质量百分比之和为100％。该发明通过多材料3D打印技术实现宏观结构及微观结构的精准调控，具有力学适配性、降解可控性和主动促进骨再生功能，适用于颅颌面、四肢长骨等大段骨缺损修复场景。
Absstract of: CN120133543A
本发明涉及一种基于极小曲面结构的多孔钽材料的制备方法及其医疗应用，尤其应用于椎间融合器、人工椎体、髋关节臼杯、关节填充块和牙种植体等医疗植入物。材料为纯钽或含钽合金（如钽钛、钽铌、钽锆、钽钛铌锆，钽含量大于1%），采用增材制造技术构建，孔隙率30~90%，其相比于桁架孔道结构（如菱形十二面体）无明显的应力集中点，在强度、模量、抗疲劳性能等方面均有显著提升，特别适合用于大面积和承重骨缺损的结构和功能重建。
Absstract of: CN120131133A
本发明提供一种骨性Ⅱ类错颌畸形正颌手术辅助器械组件及其制备方法，截骨辅助部件包括固定支持夹板与第一定位导板，第一定位导板中设有截骨定位槽、钛钉定位孔与髁突位置指示孔，固定支持夹板与第一定位导板通过第一连接杆保持固定姿态连接；定位辅助部件包括咬合夹板、髁突定位板与第二定位导板，髁突定位板贴合于患者的近心段下颌支表面，与患者的下颌支固定连接，第二定位导板中设有钛板定位框，咬合夹板分别与髁突定位板及第二定位导板通过第二连接杆及第三连接杆保持固定姿态连接。通过本发明，可建立与患者颌骨精准适配的截骨辅助部件与定位辅助部件，实现对颌骨的定位与固定功能。
Absstract of: CN120132042A
本发明公开了一种兼具抗菌与促成骨性能的钛基植入物及其制备方法和应用，属于生物医用材料与生物医学交叉技术领域。本发明以选区激光熔化多孔钛合金为基体，利用微弧氧化和水热处理，在其表面构建兼顾抗菌及促成骨的多功能复合涂层；并通过掺杂功能性元素对涂层的微观结构及生物学性能进行调控，从而对涂层的抗菌性能和促成骨性能进行优化。
Absstract of: US2025186502A1
A device that allows for either fat graft preparation or cell fraction harvest is disclosed. The device includes a first centrifuge tube configured to receive and process a biological substance, the first centrifuge tube comprising an upper cylindrical portion and a lower conical portion, a sterile tissue inlet fitting, at least one sterile processing fluid inlet fitting, a sterile suction fitting, and at least one sterile extraction port connected to a first extraction tube. The first centrifuge tube further includes an internal space including a screen being positioned therein, the screen being configured to divide the internal space in half, and a filter positioned therein, the filter being positioned below the screen in the lower conical portion of the first centrifuge tube. The device may further include a second centrifuge tube configured to receive and further process the biological substance from the first centrifuge tube. The second centrifuge tube has at least one sterile fitting, wherein the second centrifuge tube is releasably connected via the at least one sterile fitting to one of the at least one sterile extraction ports of the first centrifuge tube.
Absstract of: US2025186656A1
A construct includes a biocompatible polymer-based shape morphing hydrogel or cell condensate that is configured to undergo multiple, reversible, and/or controllable different shape transformations over time via either pre-programmed design or user-controlled environmental condition alterations, wherein the hydrogel is cytocompatible and, upon degradation, produces substantially non-toxic products.
Absstract of: CN119278190A
The invention relates to a chemical combination for producing a ceramic dispersion or a ceramic gel, to a method for producing a ceramic molded part, and to a ceramic molded part produced by the method.
Absstract of: US2023210752A1
A cosmetic composition including a solvent A, a solvent B, a polymer C and a colorant. The solvent A is at least one selected from the group consisting of ethanol, n-propanol and isopropanol. A boiling point of the solvent B is 150° C. or higher. The solvent B is compatible with the solvent A, and the polymer C is soluble in the solvent A and insoluble in the solvent B. A content of the solvent B is 5% by mass or more and 40% by mass or less, and a ratio by mass of a content of the solvent A to a content of the solvent B solvent A/solvent B in the cosmetic composition is 1 or more and 15 or less.
Absstract of: US2025190637A1
A method of manufacturing an interface for a body part is described. The method includes the step of selecting an inner radial dimension of the interface to have a plurality of compression areas that extend along the long axis of the interface. The method also includes the step of spacing the plurality of compression areas circumferentially around the long axis of the interface to create a compression pattern. The compression pattern is sized and dimensioned to reduce motion of the skeletal structure towards a wall of the interface when the interface is worn on the body part by compressing soft tissue of the body part against the skeletal structure.
Absstract of: WO2025118246A1
Provided are a bone repair material, a preparation method therefor, and use thereof. The bone repair material is prepared by printing with a material slurry by means of a photocuring 3D printing method and then sintering. The material slurry comprises the following components: 55-65% by mass of bioactive glass, 30-40% by mass of photosensitive resin, 1-5% by mass of a dispersing agent, and 0.1-1% by mass of a photoinitiator. The bone repair material has excellent biocompatibility and relatively high porosity, with the hemolysis rate lower than 5% and the cytotoxicity less than 30%. In addition, the bone repair material has relatively good morphology and relatively superior mechanical properties, and thus can be used as a bone repair scaffold material.
Absstract of: WO2025120338A1
Biodegradable 3D printed structure for bone augmentation (1) comprises an outer structure (100) and an inner structure (200) that are printed from polylactide (PLA), wherein the inner structure (200) is filled with a chitosan and hydroxyapatite gel and the outer structure (100) is coated with a chitosan and hydroxyapatite composite. The outer structure (100) has a tunnel-like shape resembling an elongated projection of the letter "U" rotated 180 degrees in depth. Implants made in the form of a biodegradable 3D-printed structure for bone augmentation as disclosed in the present invention can be adapted to each individual patient and each individual situation, which will optimize the dentist's time required for the procedure and treatment, and will also facilitate the recovery of the patient due to the reduction of the invasiveness of the procedure. This makes the entire procedure faster, simpler, and painless, but also financially acceptable for patients.
Absstract of: US2025186062A1
A resection guide locator includes a bone engagement portion with surfaces that are complementary to the surface topographies of a bone to be resected during surgery. A housing includes a socket defined by a resilient annular wall that is sized and arranged so to accept a resection guide by press-fit to thereby position and hold the resection guide within the socket. The resection guide is maintained in a predetermined, preferred position while the surfaces are releasably locked in position on the bone. A method is disclosed for forming and using the resection guide locator.
Absstract of: US2025188298A1
The present invention provides three-dimensional, cell-laden bioink scaffolds, methods of making and using the same.
Absstract of: US2025187357A1
The present invention provides a printing mechanism for a medical monitoring device and a medical monitoring device. The printing mechanism comprises a support plate, a movable frame assembly disposed movably on the support plate. the movable frame assembly comprising a frame, and a print paper drawer for holding the print papers, the print paper drawer being mounted on the frame to move along with the movable frame assembly. The printing mechanism further comprises at least one set of spaced sleeves provided on a top surface of a body of the support plate in a movement direction of the movable frame assembly. and a guide rod passing through holes defined by each set of the spaced sleeves and secured to a bottom of the frame at two ends. the guide rod guiding the movable frame assembly and moving along with the movable frame assembly, wherein a damping bracket is provided between adjacent sleeves of each set of the spaced sleeves, the damping bracket contacts the guide rod and exerts an upward force onto the guide rod perpendicularly to a movement direction of the guide rod. The printing mechanism for the medical monitoring device according to the present invention may ensure that the print paper drawer is positioned with high accuracy and is opened and closed smoothly when the printing mechanism operates in the horizontally arranged state or the vertically hung state.
Absstract of: US2025187262A1
A resin based material whose composition includes a light-curable mixture of monomers of no more than 35 wt. % of an ethoxylated difunctional bisphenol A dimethacrylate; of no more than 10 wt. % of a methacrylate monomer; of no more than 10 wt. % of a difunctional urethane acrylate; of no more than 0.1 wt. % of an optical brightener; of no more than 5 wt. % of silica particles having methacrylate functionalization layers and having an average particle size of less than about 200 nm; of having more than 40 wt. % of an inert glass; of no more than 15 wt. % of a heavy metal oxide; of no more than 2.5 wt. % of an ultraviolet/visible (UV/Vis) light-photo-polymerization initiator; a colorant; and a stabilizer.
Absstract of: WO2025120283A1
The invention relates to a method for manufacturing a removable partial dental prosthesis, the method comprising the steps of: a) manufacturing at least one monolithic block comprising an artificial tooth part and an artificial gum part, the monolithic block comprising at least one first joining member; b) manufacturing a frame that is configured to support the monolithic block, the frame comprising at least one second joining member; then c) joining the monolithic block to the frame by interlocking the first joining member with the second joining member to form the removable partial dental prosthesis.
Absstract of: WO2025120669A1
The present disclosure provides a three-dimensional hydrogel prepared using a bioink composition comprising methacrylated hyaluronic acid, methacrylated gelatin, a photoinitiator and a photoabsorber; and a method for preparing the three- dimensional hydrogel or lenticule. The present disclosure further provides a method of treating corneal tissue repair in a subject in need thereof using the three- dimensional hydrogel or lenticule.
Nº publicación: WO2025122495A1 12/06/2025
Applicant:
CZ BIOHUB SF LLC [US]
THE REGENTS OF THE UNIV OF CALIFORNIA [US]
CZ BIOHUB SF, LLC,
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Absstract of: WO2025122495A1
Composite matrix materials including a plurality of microgel particles having a mean particle size in a range of about 1 μm to about 100 μpm, and an interstitial matrix, where the composite matrix is characterized by reversible yield-stress behavior at 4°C; methods of preparation of the composite matrix materials; and methods of preparing organoids from the composite matrix materials are disclosed.
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