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3D bioprinting

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LastUpdate Updated on 14/09/2026 [07:19:00]
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MEDICAL APPARATUS FOR MULTI-ANGLE IMAGING

Publication No.:  US20260262933A1 10/09/2026
Applicant: 
OPTOSURGICAL LLC [US]
OPTOSURGICAL LLC
US_20260262933_A1

Absstract of: US20260262933A1

A system for generating a multi-angle visualization of tissue of a patient. The system includes a medical device having one or more imaging devices disposed at the distal end for measuring a continuous stream of 2D quantitative visual data. The system further includes a computing device configured to accept the one or more continuous streams of 2D quantitative visual data from the one or more imaging devices, generate a depth map, backproject the depth map into 3D object space, resulting in a 3D point cloud, define a virtual camera position relative to the 3D point cloud, generate, based on the 3D point cloud and the virtual camera position, the multi-angle visualization of the tissue, and display the multi-angle visualization of the tissue.

Cell systems using spheroids and methods of making and using the same

Publication No.:  AU2026204971A1 10/09/2026
Applicant: 
THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND
AXOSIM INC
The Administrators of the Tulane Educational Fund
Axosim, Inc.
AU_2026204971_A1

Absstract of: AU2026204971A1

The present disclosure generally relates to a cell culturing system, and specifically to a three-dimensional cell culturing system for neuronal cells that promotes both structural and functional characteristics that mimic those of in vivo peripheral fibers, including cell myelination. Using a dual hydrogel construct and spheroids comprising neuronal cells, the present disclosure provides methods, devices, and systems for in vitro spatially-controlled, three-dimensional models that permit intra- and extra-cellular electrophysiological measurements and recordings. The three-dimensional hydrogel constructs allow for flexibility in incorporated cell types, geometric fabrication, and electrical manipulation, providing viable systems for culture, perturbation, and testing of biomimetic neural growth with physiologically-relevant results. BSTRACT

COMPOSITIONS FOR WOUND GRAFTS AND RELATED METHODS

Publication No.:  WO2026188152A1 10/09/2026
Applicant: 
TIDES MEDICAL LLC [US]
SAFAVIEH MOHAMMADALI [US]
RIVERA TARAZONA LAURA KATHERINE [US]
MELICAN MORA CAROLYNNE [US]
TIDES MEDICAL, LLC
SAFAVIEH, Mohammadali
RIVERA-TARAZONA, Laura, Katherine
MELICAN, Mora, Carolynne
WO_2026188152_A1

Absstract of: WO2026188152A1

The present disclosure generally relates to bioink compositions and methods thereof. Other aspects of the disclosure relate to articles produced using a 3D printer and one or more bioinks disclosed herein. Additional aspects of the disclosure further provide for methods of 3D printing a tissue graft using one or more of the bioinks disclosed herein. The bioink-derived tissue grafts may be used to enhance wound healing and/or tissue regeneration of non-healing wounds.

Ultrasound-Based Elastography Through Shear-Wave Measurement

Publication No.:  US20260263046A1 10/09/2026
Applicant: 
FUJIFILM SONOSITE INC [US]
FUJIFILM SonoSite, Inc.
US_20260263046_A1

Absstract of: US20260263046A1

0000 Systems, devices, and methods for ultrasound-based elastography through shear-wave measurement are described. In some implementations, an ultrasound system generates ultrasound data from an ultrasound scan of an anatomy, such as a bodily structure of an organism. The system generates one or more push pulses to induce one or more corresponding shear waves in the anatomy being scanned. The one or more shear waves are scanned by the system, producing shear wave ultrasound data, which is used by the system to determine one or more features of the anatomy being scanned (speed-of-sound, elasticity of the anatomy, etc.). According to some embodiments, the one or more features of the anatomy are further based on the ultrasound data.

Verfahren zum Betreiben eines medizinischen Visualisierungssystems und medizinisches Visualisierungssystem

Publication No.:  DE102025112252B3 10/09/2026
Applicant: 
ZEISS CARL MEDITEC AG [DE]
Carl Zeiss Meditec AG
DE_102025112252_PA

Absstract of: DE102025112252B3

Die Erfindung betrifft ein Verfahren zum Betreiben eines medizinischen Visualisierungssystems, wobei das medizinische Visualisierungssystem (1) mindestens eine Bilderfassungseinrichtung (6), mindestens eine Auswerteeinrichtung (8) und mindestens eine Informationsausgabeeinrichtung umfasst, umfassend die Schritte:• Empfangen (ES) mindestens eines Bildsignals (S_A), das eine Bildsequenz mit mindestens einem Abbild repräsentiert, welches durch die mindestens eine Bilderfassungseinrichtung (6) von einem Untersuchungsbereich (2) erzeugt wurde,• Bereitstellen (BS) von mindestens einem Eingabedatenpunkt (EDP1) für die Verarbeitung durch mindestens ein erstes maschinell erlerntes Modell (MLM1), wobei der Eingabedatenpunkt (EDP1) zumindest in Abhängigkeit des Bildsignals (S_A) bereitgestellt wird,• Verarbeiten (VS) des mindestens einen Eingabedatenpunkts (EDP1) mit der Auswerteeinrichtung (8) durch mindestens das erste maschinell erlernte Modell (MLM1) zur Erzeugung eines Ausgangssignals (AS), welches Informationen über mögliche bildsignalspezifische Messaufgaben (MA1,..., MAn) umfasst, wobei eine bildsignalspezifische Messaufgabe (MA1,..., MAn) die Bestimmung mindestens einer dimensionellen Größe eines abgebildeten Elements bezeichnet,Ansteuern der mindestens einen Informationsausgabeeinrichtung in Abhängigkeit des Ausgangssignals (AS), sowie ein medizinisches Visualisierungssystem (1).

METHOD FOR GENERATING CUSTOM COMPRESSION GARMENT WITH CHAINMESH

Publication No.:  WO2026187753A1 10/09/2026
Applicant: 
OPENSUIT CORP [US]
OPENSUIT CORPORATION
WO_2026187753_A1

Absstract of: WO2026187753A1

One variation of a method includes: accessing a virtual mesh representing a body part; calculating a center line of the virtual mesh; radially downscaling the virtual mesh, radially about the center line, according to a target radial compression for a compression garment; projecting a primary rotation axis of a joint, represented in the virtual mesh, onto the virtual mesh; and calculating a neutral plane corresponding to minimal axial displacement of soft tissue proximal a joint during articulation of the joint. This variation of the method also includes generating a three-dimensional model of the compression garment including: virtual compression links that cooperate to achieve the target radial compression proximal the joint and exhibit a first longitudinal compliance based on proximity to the primary rotation axis and the neutral plane; and virtual connector links that link pairs of adjacent virtual compression links.

METHODS AND KITS USEFUL FOR DETERMINING DISEASE LOCATION IN AN INDIVIDUAL SUFFERING FROM INFLAMMATORY BOWEL DISEASE

Publication No.:  US20260265841A1 10/09/2026
Applicant: 
THE CHINESE UNIV OF HONG KONG [CN]
The Chinese University of Hong Kong
US_20260265841_A1

Absstract of: US20260265841A1

0000 In some embodiments, provided is a method for identifying a stool sample with an altered microbiome associated with IBD with disease above TI comprising the steps of: a) determining the relative abundance of a set of bacterial species in the stool sample; b) comparing the relative abundance of each bacterial species in the set of bacterial species from the individual with the relative abundance of each bacterial species in the set of bacterial species in a reference data set to generate a risk score; and c) determining the stool sample as having an altered microbiome associated with IBD with disease above the TI if the risk score is higher than a cutoff value. Other embodiments are described herein. In some embodiments, provided methods, kits, products and uses of compositions provide a cost-effective, non-invasive method to support clinical decision making, and hence to help improve disease management regarding disease above TI.

Process for Manufacturing Dental Implant, Device for Anodizing Dental Implant and Device for Acid Etching and Coating of Dental Implant

Publication No.:  US20260263196A1 10/09/2026
Applicant: 
M3 HEALTH IND E COMERCIO DE PRODUTOS MEDICOS ODONTOLOGICOS E CORRELATOS S A [BR]
M3 HEALTH IND\u00DASTRIA E COM\u00C9RCIO DE PRODUTOS M\u00C9DICOS, ODONTOL\u00D3GICOS E CORRELATOS S.A.
US_20260263196_A1

Absstract of: US20260263196A1

A 3D printed dental implant manufacturing process in which a chemical treatment process is carried out, on the external surface of said implant; and an anodizing process on the inner surface of the cavity of said implant. A device for aligning an implant body for the CNC machining process through a collet shaft; an implant cavity anodizing device; and a device for etching the outer surface of an implant configured to be implemented in an implant manufacturing process, wherein the implant manufacturing process can be automated and performed on multiple implants simultaneously.

ELECTRONIC DEVICE FOR PROVIDING MESSAGE ABOUT HEALTH CARE AND OPERATION METHOD THEREOF

Publication No.:  US20260269037A1 10/09/2026
Applicant: 
SAMSUNG ELECTRONICS CO LTD [KR]
SAMSUNG ELECTRONICS CO., LTD.
US_20260269037_A1

Absstract of: US20260269037A1

An electronic device comprises at least one processor and a memory storing instructions. The instructions may be individually or collectively executed by the at least one processor to instruct the electronic device to generate a message for the health care of a user on the basis of state information about the user and first information. The instructions may be individually or collectively executed by the at least one processor to instruct the electronic device to determine whether the message is suitable for the health state of the user on the basis of second information and profile information about the user.

X-RAY SYSTEM AND METHOD FOR TISSUE STRUCTURAL ANALYSIS AND IMAGING

Publication No.:  US20260263021A1 10/09/2026
Applicant: 
EOSDX INC [US]
EosDx Inc.
US_20260263021_A1

Absstract of: US20260263021A1

0000 A method of controlling an X-ray system can include placing a breast of a patient onto a breast positioning area, moving a diffraction enhanced X-ray imaging apparatus of the X-ray system to the breast positioning area, performing a diffraction enhanced X-ray imaging measurement, and transmitting, to a work-station, diffraction enhanced X-ray imaging results. The method can further include moving the diffraction enhanced X-ray imaging apparatus away from the breast positioning area, moving a diffractometer apparatus of the X-ray system into the breast positioning area, performing a diffractometer measurement using the diffractometer apparatus to obtain diffractometer measurement results, and transmitting the diffractometer measurement results to the work-station. In some cases, the method can further include processing the diffraction enhanced X-ray imaging results using the work-station to determine coordinates of potential cancer sites in the breast positioning area, and performing diffractometer measurements at the coordinates.

Modular Nozzle for Coaxial Extrusion

Publication No.:  US20260264305A1 10/09/2026
Applicant: 
CELLINK BIOPRINTING AB [SE]
Cellink Bioprinting AB
US_20260264305_A1

Absstract of: US20260264305A1

The present invention relates to a nozzle (30) for coaxial extrusion-based bioprinting comprising multiple separate modules comprising an inlet (12), an extrusion channel and an outlet. The modules are adapted to be assembled and reassembled and are configured such that the extrusion channels are essentially coaxially and concentrically aligned along the longitudinal axis of a first module when forming a nozzle.

Estimation Of Blood Loss Within A Waste Container Of A Medical Waste Collection System

Publication No.:  US20260268510A1 10/09/2026
Applicant: 
STRYKER CORP [US]
Stryker Corporation
US_20260268510_A1

Absstract of: US20260268510A1

Methods for estimating blood loss within a waste container of a medical waste collection system in which an imaging device is supported with a device cradle. The method includes analyzing an image, such as image frames of a video feed, to determine a fluid volume and a blood component within the waste material. The images may be aligned based on reference markers, and the method includes segmenting the images to determine blood, meniscus, and non-blood classes. The fluid meniscus of the waste material may be identified, and mapped to a canonical coordinate space for pixel to volume conversion. Calibration data associated with the reference markers may be used to do so. At least one region of the interest associated with an insert disposed within the waste container is analyzed. The estimated blood loss, based on the determined fluid volume and the blood component, may be displayed in real-time.

SACROILIAC JOINT FIXATION AND FUSION IMPLANTS

Publication No.:  US20260263117A1 10/09/2026
Applicant: 
GLOBUS MEDICAL INC [US]
GLOBUS MEDICAL, INC.
US_20260263117_A1

Absstract of: US20260263117A1

0000 Bone implants, assemblies, and methods thereof. The implants may include a tulip head and a bone fastener including a screw shank with bone threads, a distal tip configured to facilitate insertion into bone, and a proximal end having a screw head receivable in the tulip head. The screw shank may define one or more longitudinal windows and/or helical cuts filled with a lattice structure that acts as a scaffold for bone healing and bone interdigitation. The bone fastener, or a portion thereof, may be 3D printed, for example, using an additive laser powder bed fusion process to provide the integrated lattice structure.

OPTICAL IMAGING DISTORTION COMPENSATION

Publication No.:  US20260269056A1 10/09/2026
Applicant: 
ALCON INC [CH]
ALCON INC.
US_20260269056_A1

Absstract of: US20260269056A1

The present disclosure relates to operations that include identifying, based on an optical imaging result corresponding to a tissue, a non-uniform layer that is disposed in an optical measurement path corresponding to the optical imaging result. The operations may also include performing one or more adjustment operations with respect to the optical imaging result based on identification of the non-uniform layer.

METHOD, APPARATUS, AND COMPUTER-READABLE RECORDING MEDIUM FOR DESIGNING MOUTH SHIELD HAVING MEDICAMENT SUPPLY UNIT

Publication No.:  US20260263765A1 10/09/2026
Applicant: 
INNODTECH INC [KR]
INNODTECH, Inc.
US_20260263765_A1

Absstract of: US20260263765A1

0000 The present invention relates to a method for designing a mouth shield having a medicament supply unit, comprising a temporary model generation step of identifying a tooth part and a gum part using a preset object extraction algorithm from oral scan data, which is obtained by three-dimensionally scanning an oral condition of a subject, and generating a temporary model by performing modeling on the mouth shield having a shape corresponding to the identified tooth part and gum part for the subject using a design program, and a definitive model generation step of generating a definitive model by performing correction on the temporary model generated in the temporary model generation step, in which the definitive model is generated by forming continuous concave groove parts in an inner region including at least one of a lingual side or a labial side of the temporary model along an arrangement direction of teeth.

METHOD, APPARATUS, AND COMPUTER-READABLE RECORDING MEDIUM FOR DESIGNING MOUTH SHIELD HAVING MEDICAMENT APPLICATION AREA

Publication No.:  US20260268031A1 10/09/2026
Applicant: 
INNODTECH INC [KR]
INNODTECH, Inc.
US_20260268031_A1

Absstract of: US20260268031A1

A method for designing a mouth shield having a medicament application area includes an object classification and identification step of classifying and identifying objects corresponding to a tooth part and a gum part from oral scan data, a temporary model generation step of generating a temporary model by performing modeling on the mouth shield having a shape to cover the tooth part and the gum part identified in the object classification and identification step using a design program, and a correction model generating step of generating a correction model, in which correction is performed on the temporary model in which a design for the temporary model is corrected such that a medicament application surface is secured in consideration of the application thickness of the medicament to be applied to an inner area of the mouth shield, thereby generating the correction model with optimized consistency of the mouth shield.

KINK AND TANGLE RESISTANT SMART-ENABLED NASAL CANNULA AND PATIENT OXYGEN CONCENTRATOR

Publication No.:  US20260263718A1 10/09/2026
Applicant: 
15892031 CANADA INC [CA]
15892031 Canada Inc.
US_20260263718_A1

Absstract of: US20260263718A1

A kink and tangle resistant smart-enabled nasal cannula is provided. An oxygen supply tube has a circular sidewall, a supply tube outer diameter, an oxygen concentrator connection end, and a patient end downstream. An electrical cable has a circular cable sidewall integrally formed with the supply tube sidewall, an electrical cable diameter less than the supply tube outer diameter, an electrical cable oxygen concentrator connection end proximate the oxygen concentrator connection end, a patient movement sensor connection end proximate the patient end, and insulated conductors extending between those ends. A patient movement sensor connector is connected to the electrical cable at the patient movement sensor connection end. A split joint has a patient interface end upstream of two oxygen supply tube ends, with the patient end of the oxygen supply tube connected to the patient interface end. A patient interface is connected thereto and has at least one nasal prong.

CHERENKOV-BASED CONTROL OF A RADIATION TREATMENT APPARATUS

Publication No.:  US20260263837A1 10/09/2026
Applicant: 
BRAINLAB SE [DE]
Brainlab SE
US_20260263837_A1

Absstract of: US20260263837A1

Disclosed is a computer-implemented method of determining control data for controlling a radiation treatment apparatus. The disclosed method encompasses, in one aspect, acquisition of a Cherenkov radiation image from a body surface of a patient and comparing it to a simulated Cherenkov radiation pattern such as for example with regard to its position relative to an anatomical body part which is designated to be irradiated with treatment radiation. The result of the comparison is used to control a radiation treatment apparatus, such as for example to switch the beam off if the comparison indicates that the position of the detected Cherenkov radiation relative to the anatomical body part is not according to plan.

ELECTRONIC DIGITAL STETHOSCOPE AND USES THEREOF

Publication No.:  US20260263028A1 10/09/2026
Applicant: 
CHILDRENS NAT MEDICAL CENTER [US]
AUSCULTECH DX LLC [US]
CHILDREN'S NATIONAL MEDICAL CENTER
AUSCULTECH DX, LLC
US_20260263028_A1

Absstract of: US20260263028A1

A digital stethoscope, including a chest piece enclosing a diaphragm; a first microphone configured to acquire a digital auscultation audio signal through the diaphragm and a second microphone configured to acquire an ambient audio signal; and a housing coupled to the chest piece and enclosing processing circuitry, wherein the processing circuitry is configured to generate and output an active noise cancelation signal based on the ambient audio signal, apply a gain to the digital auscultation audio signal, apply a digital filter to the digital auscultation audio signal, and stream the digital auscultation audio signal to external processing circuitry while acquiring the digital auscultation audio signal, and wherein the external processing circuitry is configured to extract a feature of the digital auscultation audio signal and classify the digital auscultation audio signal as including a Still's murmur based on the extracted feature.

LEAD ADAPTER FOR IMPLANTABLE PULSE GENERATOR AND METHOD OF AUTOMATICALLY CONFIGURING THE IMPLANTABLE PULSE GENERATOR FOR A LEAD CONFIGURATION

Publication No.:  AU2025243979A1 10/09/2026
Applicant: 
THE ALFRED E MANN FOUNDATION FOR SCIENT RESEARCH
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH
AU_2025243979_PA

Absstract of: AU2025243979A1

A lead splitter adapter for an implantable pulse generator includes a plug portion configured to plug into a receptacle of an implantable pulse generator. The plug portion includes electrical contacts, and at least two of the electrical contacts, a first electrical contact from within the first lead receptacle and a second electrical contact from the second lead receptacle, which first and second electrical contacts are shunted by an electrical connection that includes at least one of a resistor, capacitor or inductor.

NEGATIVE AND/OR POSITIVE PRESSURE THERAPY DEVICES AND METHODS WITH NATURAL LANGUAGE INTERFACES

Publication No.:  AU2025239707A1 10/09/2026
Applicant: 
T J SMITH AND NEPHEW LIMITED
T.J.SMITH AND NEPHEW, LIMITED
AU_2025239707_PA

Absstract of: AU2025239707A1

A negative and/or positive pressure therapy system can include a therapy device with a pressure source configured to provide a pressure therapy to a wound site covered by a wound dressing and a controller configured to control operation of the pressure source. The system can include a storage medium storing executable instructions that, when executed by one or more processors, cause the one or more processors to receive a natural language query associated with provision of the pressure therapy, the natural language query being issued by a user of the therapy device, using one or more machine learning models trained solely with data provided by a manufacturer of the therapy device, process the natural language query and determine a response, and provide the response to one or more of the user or the controller.

STERILE FIELD SURGICAL IMAGING SYSTEM AND METHOD

Publication No.:  AU2025240472A1 10/09/2026
Applicant: 
OCEAN ORTHOPEDICS INC
OCEAN ORTHOPEDICS, INC.
AU_2025240472_PA

Absstract of: AU2025240472A1

A surgical imaging system for communicating images from an imaging sensor to a display device within an operating room has a video controlling unit configured to receive the images from the imaging sensor. The video controlling unit is sterile or sterilizable sufficient for use in the sterile field of an operating room. The video controlling unit is configured to atraumatically rest on the patient during the procedure.

MANAGEMENT SYSTEM AND SENSOR

Publication No.:  US20260262941A1 10/09/2026
Applicant: 
NITTO DENKO CORP [JP]
NITTO DENKO CORPORATION
US_20260262941_A1

Absstract of: US20260262941A1

0000 A management system includes a device configured to be attached to a human body and a management device, wherein the management device includes an acquisition unit configured to acquire image data including an image of the device attached to the human body and an image indicating a physical characteristic of the human body, an extraction unit configured to extract, from the image data, authentication information identifying the human body and information acquired from the device, and a storage control unit configured to store the information acquired from the device in association with the authentication information in a storage unit.

PATIENT-SPECIFIC TOTAL HIP ARTHROPLASTY PERIPROSTHETIC FRACTURE RISK CALCULATOR

Publication No.:  US20260269071A1 10/09/2026
Applicant: 
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RES [US]
Mayo Foundation for Medical Education and Research
US_20260269071_A1

Absstract of: US20260269071A1

Provided herein is a computer-implemented method including obtaining values for non-modifiable risk factors, each defining an immutable patient characteristic determined to impact a likelihood that a complication results from an arthroplasty procedure. The system obtains first candidate values for modifiable risk factors of the patient defining a mutable characteristic of the patient or the arthroplasty procedure. The first candidate values are determined to minimize the likelihood that the complication results from the arthroplasty procedure. The system obtains second candidate values for the modifiable risk factors of the patient determined to maximize the likelihood that the complication results from the arthroplasty procedure. The system determines a personalized risk interval that represents a range of modifiable risk for the patient with respect to the arthroplasty procedure including determining (i) a lower bound and (ii) an upper bound for the personalized risk interval; and providing an output indicative of the risk interval.

SYSTEMS AND METHODS FOR REMOVING STIMULATION ARTIFACTS FROM PHYSIOLOGICAL RECORDINGS

Nº publicación: US20260263010A1 10/09/2026

Applicant:

OHIO STATE INNOVATION FOUND [US]
Ohio State Innovation Foundation

US_20260263010_A1

Absstract of: US20260263010A1

0000 Disclosed herein are of systems, methods, and computer-program products for removing stimulation artifacts of electrical physiological recordings that contain both the stimulation artifact and the neural response.

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