Alerta

Integrated AI-Powered Wearable Device and Retinal Imaging System for Early Home-Based Screening and Detection of Ocular Tumors

Absstract of: US20260253215A1

The RetinAI invention provides a novel integrated system designed for home-based early screening and detection of ocular tumors and retinal diseases, leveraging advanced artificial intelligence and optical imaging technology. The system comprises a wearable headset with precisely aligned imaging sensors and dual-mode illumination sources for capturing extraocular images to detect leukocoria and intraocular retinal images for direct visualization of tumors, eliminating the need for pharmacological pupil dilation. On-device deep learning models, including representative object detectors and convolutional neural networks, provide real-time diagnostic outputs. Clinical validations demonstrate RetinAI's capability to detect leukocoria as small as 1 mm in diameter and identify a broad spectrum of retinal diseases, confirming its significant potential to enhance ocular health screening, particularly in underserved and resource-limited settings. The cost-effective, user-friendly, and portable nature of the RetinAI system positions it as an essential tool for improving access to ophthalmic care globally.

CUSTOMIZABLE PATIENT MONITORING DEVICE AND SYSTEM

Absstract of: WO2026177966A1

Patient monitoring devices, systems and methods are provided. A customizable patient monitoring device may include multiple ports allowing connection and disconnection of any of various physiological sensors. Signals from physiological sensors may be processed to obtain clinically presentable physiological information, which may include accessing the information from the signals or computing the information based at least in part on the signals. An arrangement of display units may be displayed on a monitoring device display of the customizable patient monitoring device, such as a grid of tiles, in which each tile may display information associated with a specific physiological parameter associated with a specific connected physiological sensor. A tile may be actuated by touch to display an enhanced display on the monitoring device display displaying additional information associated with the specific physiological parameter. The enhanced display may be actuated by touch to provide further information associated with the specific physiological parameter.

PERSONALIZED DIGITAL THERAPEUTICS FOR SKILLS TRAINING USING ROLE-BASED INTERACTIONS

Absstract of: US20260253748A1

Various examples, systems, and methods are disclosed relating to a roleplay pipeline for treatment and skill development. One or more processors can receive, for a roleplay interaction having a defined role for a user and a defined role for a chatbot, content in the roleplay interaction. The one or more processors further can apply the content as input to at least one artificial intelligence (AI) model to cause the at least one AI model to generate an output for the chatbot. The one or more processors further can provide, via a chatbot interface, the output. The digital therapeutic application can improve treatment by providing structured roleplay interactions that support social engagement, strengthen emotion regulation, and improve skill development and can increase the efficacy of the medication that the user is taking to address social skills, emotion skills, behavior challenges, and/or cognitive processing deficits.

VISION-BASED DETECTION OF ACCESS SHEATH

Absstract of: WO2026176271A1

This disclosure provides methods, devices, and systems for controlling robotically assisted medical systems. The present implementations more specifically relate to techniques for vision-based detection of an access sheath. In some aspects, a controller for a medical system obtains a series of images captured by a camera disposed on a distal tip of a medical instrument that is at least partially inserted through an access sheath. The controller infers a respective segmentation mask from each image in the series based on a machine learning model trained to classify each pixel of the image as depicting the access sheath or not depicting the access sheath, where the segmentation mask indicates how many pixels of the image are classified as depicting the access sheath. The controller further determines a position of the distal tip of the instrument relative to the access sheath based on the segmentation masks for the series of images.

WEARABLE ELECTRONIC DEVICE AND METHOD FOR DETECTING FINGER SIZE CHANGE USING SAME

Absstract of: WO2026177387A1

According to an embodiment of the present disclosure, a wearable electronic device may comprise: a housing having a ring shape; a plurality of pressure sensors spaced apart from each other in an inner space of the housing; at least one processor including processing circuitry; and a memory for storing instructions. According to an embodiment, the instructions, when executed individually or collectively by the at least one processor, may cause the wearable electronic device to obtain a plurality of pressure values through the plurality of pressure sensors. According to an embodiment, the instructions, when executed individually or collectively by the at least one processor, may cause the wearable electronic device to compare the plurality of obtained pressure values. According to an embodiment, the instructions, when executed individually or collectively by the at least one processor, may cause the wearable electronic device to determine, on the basis of a result of the comparison, that pressure has been generated according to the size of the finger of a user wearing the wearable electronic device, if the difference between the plurality of pressure values is within a designated range. In addition to various embodiments disclosed in the present document, other various embodiments are possible.

SYSTEMS AND METHODS FOR PROFILING COGNITIVE ABILITIES

Absstract of: US20260253505A1

0000 A system and method for measuring and assessing cognitive abilities of a user are disclosed. The method includes generating an individualized assessment protocol comprising a plurality of tasks each configured to evaluate cognitive mental specification. The method also includes the user selecting at least one task tasks using a semi-random process. The method further includes displaying a task-specific interface to present the selected task to user. The method includes receiving user responses to the task along with associated parameters. The method includes transmitting an individualized performance score table to a server. The method also includes processing the individualized performance scores using a population database, a neural network classifier, and regression models, which adjust their parameters based on the received scores. The method further includes computing individualized assessment scores to generate a profile of cognitive mental abilities. The method also includes transmitting profile of cognitive mental abilities to user device.

SYSTEM AND METHOD FOR PROVIDING PERSONALIZED WELLNESS ACTIVITY INFORMATION BASED ON USER PHYSICAL CONDITION INFORMATION AND USER SCHEDULE INFORMATION

Absstract of: KR103010329B1

실시예들은 사용자의 신체 상태 정보 및 스케줄 정보를 기반으로 맞춤형 웰니스 정보를 사용자 단말에게 제공하는 시스템 및 방법을 제시한다. 일 실시예에 따른 상기 방법은, 상기 사용자 단말로부터 체형 분석 정보, 체성분 분석 정보, 신체 활동에 대한 설문 정보 및 사용자 스케줄 정보를 포함하는 웰니스 추천 요청 메시지를 수신하고, 상기 체형 분석 정보, 상기 체성분 분석 정보 및 상기 신체 활동에 대한 설문 정보를 기반으로 상기 사용자 단말에 대한 신체 상태 정보를 생성하고, 상기 사용자 단말에 대한 신체 상태 정보는 상기 체형 분석 정보에 기반한 복수의 관절 각각에 대한 모빌리티 스코어, 상기 체성분 분석 정보에 기반한 체구성 스코어와 상기 신체 활동에 대한 설문 정보에 기반한 위험 벡터 및 목표 벡터를 포함하고, 상기 복수의 관절 각각에 대한 모빌리티 스코어, 상기 체구성 스코어 및 상기 위험 벡터를 기반으로 ICI(Intensity Capacity Index) 및 RNI(Recovery Need Index)를 산출하고, 사전 설정된 강도 매핑 테이블을 기반으로 상기 ICI를 복수의 강도 밴드 중 어느 하나의 강도 밴드에 매핑함으로써, 매핑된 강도 밴드에 대응하는 클래스 집합을 결정하고, 상기 RNI 및 상기 목표 벡터를 기반으로 사전 설정된 도메인 가중�

PREDICTING A TREATABLE HUNTINGTON'S DISEASE PATIENT/PATIENT POPULATION AND EFFECTS ON DISEASE PROGRESSION FOR THERAPIES TARGETING SOMATIC INSTABILITY

Absstract of: WO2026178535A1

Somatic instability (SI) in the mutant HTT allele is a high value therapeutic target for Huntington's Disease (HD). However, rates of SI and the speed of HD progression vary widely with inherited germline CAG repeat lengths across the HD patient population. Understanding this variability and projecting the treatable range of patients for SI-directed therapies is important to their design, preclinical development, and conferring optimal benefit to HD patients. A computational model and related method(s) track the percentage of healthy medium spiny neurons (MSNs) across the lifetime of HD patients. Changes in MSN survival are predicted based on an exemplary SI-directed interventional gene therapy. The range of treatable patients is also projected. The flexible framework provided by the computational model and related method(s) enables therapeutic performance prediction and projecting outcomes across the HD patient population and furthermore, serves as a valuable tool for defining the target populations for SI-directed therapies.

BONE ANCHORING DEVICE

Absstract of: US20260248538A1

A bone anchoring device for coupling a rod to bone includes an anchoring element with a shank and a head, a receiving part having a central axis, a channel for receiving the rod, and an accommodation space for accommodating the head of the anchoring element, and a pressure element positionable at least partially in the accommodation space to exert pressure on the head. The pressure element is configured to extend to an axial position that is lower than an axial position of a portion of the head having a greatest diameter.The head is pivotable relative to the receiving part, and has a first cooperating surface spaced apart axially from a free end of the head that is engageable with a second cooperating surface that is separable from the pressure element to limit pivoting of the head relative to the receiving part to a single plane.

INTRAORAL SCANNER WITH AN ANTENNA

Absstract of: US20260248374A1

Embodiments can relate to an intraoral scanner including a projector unit configured to emit light at least onto a dental object of a patient, and an image sensor configured to acquire reflected light from at least the dental object. The scanner includes a wireless interface configured to communicate with an external device, where the communication may include 2D image data and/or 3D image data processed or raw. The scanner includes a housing accommodating the projector unit and the image sensor, and wherein the housing includes a first end and a second end, and the projector unit and the image sensor are arranged closer to the first end, and an antenna of the wireless interface is arranged closer to the second end, and wherein during a scan of an oral cavity the first end is located inside the oral cavity and the second end is not located within the oral cavity.

IMAGE-GUIDED NAVIGATION DEVICES, ADAPTERS AND SYSTEMS WITH OPTICAL DISTANCE SENSOR BASED MARKERLESS REGISTRATION, DEPTH DETECTION, IMAGE-GUIDED PREDICTION AND TRAINING MODELS

Absstract of: US20260248563A1

A navigation device, adapter or system for real time three-dimensional (3D) depth sensing through endoscope, a laparoscope, an arthroscope, a cystoscope, a ureteroscope, a bronchoscope, a sinuscope, and a borescope devices. The navigation devices or systems can include a modular, releasable adapter that enables LiDAR or other optical time-of-flight sensor with the devices. The devices, adapters or systems are operable to generate sub-millimeter precision reconstructions of the viewed surfaces and can register the surfaces to scans, such as preoperative scans, to facilitate accurate, image-guided procedures, particularly those procedures involving precise actions, such as surgical procedures performed on rigid anatomy. Applications include surgical guidance, augmented reality visualization, distance-based signal normalization, 3D measurement, luminal traversal tracking, and robotic control, all using off-the shelf endoscopes and surgical cameras as well as borescopes. The time-of-flight sensor may be sensitive to a subrange of visible light such that the system readily supports simultaneous acquisition of visible light imaging, fluorescence, and depth data, with calibration workflows for wide field of view optics and adaptive software control of focus, illumination, and display rendering.

METHOD AND DEVICE FOR ASSESSMENT OF PERIPHERAL NEUROPATHY

Absstract of: US20260248441A1

0000 The invention relates to ways for determining, whether or not a person suffers from peripheral neuropathy. In order to make the generation of data for the determination easy for the person, the invention provides that sensor data from foot bottom pressure sensors (11, 12) used by the person to control computer games is used to determine, whether or not a person suffers from peripheral neuropathy.

DROPLET DEVICE WITH FLOW ELEMENT

Absstract of: US20260249023A1

0000 An electronically actuated droplet delivery device includes a housing having an airflow passage extending from an aperture plate to a mouthpiece and a flow element at an airflow entrance side of the housing. A fluid reservoir is in fluid communication with the aperture plate, which has a plurality of openings, and an electronic actuator vibrates the aperture plate at a frequency to generate an ejected stream of droplets. A sensor in fluid communication with the airflow passage detects an inhalation flow condition and triggers actuation of the aperture plate.

METHOD FOR PRODUCING PATIENT-OPTIMISED DOSAGE FORMS

Absstract of: ZA202307295B

The present application relates to methods of personalised pharmaceutics. More specifically, the invention relates to methods for the production of pharmaceutical dosage forms, which are produced by 3D and/or 2D printing, whereby a wide variety of parameters relevant to the administration of the dosage form can be changed depending on the analysis of patient- and disease-specific data and can be adapted in the course of the patient's treatment. In this way, the quality of treatment for the patient can be improved in the future and significantly increased from the point of view of patient safety.

SYSTEM MAINTAINANCE TECHNIQUES

Absstract of: WO2025088603A1

A service providing apparatus is disclosed comprising a service platform configured for movement along a path having one or more object treatment zones, each object treatment zone comprising equipment configured to apply one or more treatment processes to surface areas of objects carried by one or more objects' platforms along said path. At least one service providing unit is mounted on the service support platform for applying one or more service procedures to the equipment of at least one of the one or more object treatment zones while the support platform is located within the at least one treatment zone, to thereby apply the one or more service procedures while the one or more objects' platforms are located along the path.

SYSTEMS, DEVICES, COMPONENTS AND METHODS FOR DETECTING THE LOCATIONS OF SOURCES OF CARDIAC RHYTHM DISORDERS IN A PATIENT'S HEART

Absstract of: EP4797280A2

0001 Disclosed are various examples and embodiments of systems, devices, components and methods configured to detect a location of a source of at least one cardiac rhythm disorder in a patient's heart. In some embodiments, electrogram signals are acquired from a patient's body surface, and subsequently normalized, adjusted and/or filtered, followed by generating a two-dimensional spatial map, grid or representation of the electrode positions, processing the amplitude-adjusted and filtered electrogram signals to generate a plurality of three-dimensional electrogram surfaces corresponding at least partially to the 2D map, one surface being generated for each or selected discrete times, and processing the plurality of three-dimensional electrogram surfaces through time to generate a velocity vector map corresponding at least partially to the 2D map. The resulting velocity vector map maybe employed to classify a patient as one of an A-type patient, a B-type patient, and a C-type patient, and to guide therapy subsequently delivered to the patient. Trained atrial discriminative machine learning models that facilitate the foregoing systems and methods, and that provide predictions or results concerning a patient's condition, are also disclosed.

ELECTRONIC DEVICE, AND METHOD FOR OUTPUTTING NOTIFICATION SIGNAL FOR MEDICATION INTAKE BY USING SAME

Absstract of: EP4796098A1

According to an embodiment, the electronic device may comprise a display, a processor, and a memory for storing a medication intake schedule, and instructions. The instructions, when executed by the processor, may cause the electronic device to: display a clock screen including an icon for at least one medication on the basis of the medication intake schedule; identify a notification time for the intake of the at least one medication on the basis of the medication intake schedule; identify an adjustment condition for a medication intake-related notification signal on the basis of the identified notification time; adjust an output time point of the notification signal for the intake of the at least one medication, on the basis of the identified adjustment condition of the medication intake-related notification signal; and display a visual effect corresponding to the icon included in the clock screen, on the basis of the adjusted output time point. Various other embodiments may be possible.

ORAL PRODUCTS, THREE-DIMENSIONAL PRINTERS USED FOR FORMING ORAL PRODUCTS, AND THREE-DIMENSIONAL PRINTING METHODS FOR FORMING ORAL PRODUCTS

Absstract of: WO2025111344A1

A method of making an oral product includes printing a first product portion of an oral product using of a three-dimensional printer. The first product portion has a first composition. The method further includes printing a second product portion of the oral product using the three-dimensional printer, the second product portion having a second composition different from the first composition, the first product portion and the second product portion defining distinct, non-mixed regions of the oral product.

A SHRINKING AND SETTING BIOINK

Absstract of: WO2025099720A1

Provided is a hybrid hydrogel composition and methods for its preparation and use in 3D printing biomaterials for tissue engineering applications. The hybrid hydrogel composition comprises discrete hydrogel particles of a first crosslinked polymeric network, interpenetrated- through and threaded by a second crosslinked polymeric network, dispersed in a medium. The first polymer is a thermo-responsive polymer, while the second is a protein-based thermo¬ denaturing polymer. The process for preparing this composition involves mixing swelled hydrogel nanoparticles of the first polymer with a non-crosslinked hydrogel of the second polymer in the presence of a crosslinking agent for the first polymer. The 3D printing method utilizes this composition below the LCST of the thermo-responsive polymer, followed by temperature increase wherein the second polymer cures and fixes the printed ink. This approach enables the creation of high-resolution structures, including artificial tissues with capillary blood vessels, featuring dimensions less than 50 μm.

POLYOXAZOLIDONE DERIVATIVES AND THEIR USE IN MEDICAL DEVICES

Absstract of: EP4541837A1

The invention provides poly(hydroxy oxazolidone) compounds (PHOx) corresponding to following formula (I) or formula (II):whereinR_1', R_2', independently of one another each denote a C1 to C20 alkyl group, preferably a C1 to C10 alkyl group, more preferably a C1 to C3 alkyl group, most preferably a methyl group, and- R₃, R₄ independently of one another each denote hydrogen or a C1 to C20 alkyl group, preferably a C1 to C10 alkyl group, more preferably a C1 to C3 alkyl group, most preferably a methyl group, and- R₅, R_5', R₆, R_6', independently of one another each denote hydrogen or a C1 to C20 alkyl group, preferably a C1 to C10 alkyl group, more preferably a C1 to C3 alkyl group, most preferably a methyl group, or an aryl group, preferably a phenyl group, and- A is an organic linking group selected from a linear, branched, saturated, unsaturated, cyclic and/or non-cyclic aliphatic, aromatic or araliphatic hydrocarbon group, preferably having 1 to 20, more preferably 1 to 12, most preferably 1 to 8 carbon atoms and optionally further containing one or more functional groups selected from ether, ester, amide, amine, carboxyl, sulfur, halogen and/or urethane, and- Optionally A, R₃ and R₄ in formula (I) are linked to each other to form a cyclic structure, and- Optionally R₅ and R_5', and/or R₆ and R_6' in formula (II) are respective

RESIN COMPOSITION FOR STEREOLITHOGRAPHY

Absstract of: EP4796568A1

0001 The present invention provides a resin composition for stereolithography that exhibits excellent strength, toughness, water resistance, and stress retention in the shaped article while reducing the amount of leachables. The present invention relates to a resin composition for stereolithography comprising a monofunctional methacrylic polymerizable compound having a plurality of independent aromatic rings (A), a polyfunctional (meth)acrylic polymerizable compound (B), and a photopolymerization initiator (C).

Orthodontic device and method

Absstract of: GB2704295A

A dental appliance 20 for correcting jaw relationships, the dental appliance comprising a lower shell for fitting over the lower set of teeth, and an upper shell for fitting over the upper set of teeth. Each of the upper and lower shells comprise a mandibular alteration ridge 42, 44 configured to project occlusally on each side of the shell. Each mandibular alteration ridge comprises at least one guide surface 32, 36 and one or more buttresses 34, 38, wherein a guide surface of a mandibular alteration ridge of the upper shell is configured to engage a guide surface of a mandibular alteration ridge of the lower shell to displace the mandible relative to the maxilla as the jaw closes. A method of correcting a Class II or Class III malocclusion using such an appliance is also disclosed. Figure 2B

METHOD FOR MANUFACTURING A GRID USING A WATER-SOLUBLE MATERIAL AND GRID MANUFACTURED BY THE SAME

Absstract of: KR103009908B1

본 개시의 방사선그리드의 제조방법은 베이스부에 희생층을 증착한 증착기판을 생성하고, 상기 희생층에서 일부를 제거하여 오목한 차폐체패턴을 포함하는 패턴기판을 생성하고, 오목한 상기 차폐체패턴에 차폐체를 채워서 차폐체형성기판을 생성하고, 상기 차폐체를 제외한 상기 희생층을 제거하여 차폐체기판을 생성하고, 상기 차폐체기판에서 상기 베이스부를 제거하여 상기 차폐체패턴에 기초한 차폐체만 남은 차폐체에어갭기판을 생성한다.

MEDICATION DELIVERY SYSTEM

Absstract of: EP4797275A1

A medication delivery system, including a wearable device configured to automatically deliver medication based on food order information received from a user computing device. The medication is delivered via a pump, and the medication may be insulin. The food order information includes timing information and/or information about the food ordered necessary to change a medication delivery. A controller determines a medication adjustment based on an estimated physiological response to the food order information. A delivery pump automatically delivers the medication, e.g., an insulin bolus, prior to or in anticipation of food consumption.

WEARABLE ELECTRONIC DEVICE AND METHOD FOR DETECTING SIZE CHANGE OF FINGER USING THE SAME

Nº publicación: KR20260129291A 26/08/2026

Applicant:

SAMSUNG ELECTRONICS CO LTD [KR]
\uC0BC\uC131\uC804\uC790\uC8FC\uC2DD\uD68C\uC0AC