Absstract of: CN122289253A
0001 本发明涉及医学图像处理技术领域,具体是一种基于肾盂旁囊肿虚拟定位系统及存储介质。存储介质存储有计算机程序,计算机程序包括程序指令,程序指令当被处理器执行时使所述处理器执行以下步骤:获取肾盂旁囊肿患者的增强尿路造影图像,并基于增强尿路造影图像构建三维泌尿系统图;在三维泌尿系统图中识别肾盂内壁掩码、囊肿掩码和手术禁忌结构掩码;根据囊肿掩码、手术禁忌结构掩码和肾盂内壁掩码得到囊肿定位区和禁刀区;基于所述囊肿定位区和所述禁刀区得到候选动刀区,并计算所述候选动刀区的每一个体素到所述囊肿掩码的投影距离;基于所述投影距离和所述候选动刀区确定开刀虚拟定位。解决了现有技术中肾盂旁囊肿手术定位不准的问题。
Absstract of: US20260177563A1
Disclosed is a sample analyzer comprising: a measurement unit configured to measure an analyte related to a dementia biomarker contained in a sample collected from a subject, the measurement unit comprising: a sample dispenser configured to aspirate the sample from a sample container and discharge the aspirated sample into a cuvette, a first reagent dispenser configured to aspirate a first reagent from a first reagent container and discharge the aspirated first reagent into the cuvette, wherein the first reagent immunologically reacts with the analyte, a second reagent dispenser configured to aspirate a second reagent from a second reagent container and discharge the aspirated second reagent into the cuvette, wherein the second reagent generates light corresponding to an amount of the reacted analyte, a detector configured to detect the generated light from a mixture of the sample, the first reagent, and the second reagent in the cuvette; a controller comprising a processor and programmed to obtain a measurement value of the analyte based on the light detected by the detector; a storage configured to store a reference value that specifies an outlier that may be caused by a factor other than dementia; and an output unit, wherein the controller is programmed to execute a determination on whether the measurement value is specified as the outlier based on the measurement value and the reference value, generate an analysis result of the dementia biomarker based on the measurement
Absstract of: CN122272298A
0001 本发明涉及尿糖监测技术领域,尤其涉及一种成人纸尿裤尿糖数据的监测方法及系统,该方法首先交互护理管理系统获取患者日常护理节点,连接穿戴终端生成可视化监测界面。其次,在预设节点利用纸尿裤内层集成的多组传感器采集数据,结合健康参数识别异常并预测血糖异常等级。随后,基于多节点历史数据在界面中生成血糖波动趋势曲线。最后,综合异常等级与趋势曲线制定个性化干预方案,实施针对性护理。本发明通过多源信号融合抗干扰,实现无创连续监测;具备血糖趋势预判能力,变被动报警为主动预防;并通过可视化界面与智能决策闭环,显著提升糖尿病患者的护理精准度、效率及舒适度。
Absstract of: CN122290919A
0001 本发明涉及人工智能与医疗信息交叉化技术领域,且公开了一种智能病房护理系统,旨在解决现有技术中护理任务信息分散、缺乏动态调度与高风险预警机制的问题。该系统包括:构建结构化护理需求数据库,动态生成全病区统一的护理任务清单,通过图形化界面多维度可视化展示任务状态,建立病重/病危等高风险状态的联动预警机制,并整合出入水量、体重等动态生理数据驱动自适应护理调度。本申请通过采用上述技术方案,能够实现护理任务的集中管理、智能预警与主动干预,显著提升护理效率并预防突发情况。
Absstract of: US20260175015A1
Embodiments of an implantable system and apparatus for providing electrical and optical deep brain stimulation are disclosed. Through the biological introduction of light-responsive opsins to neurons, the system is operable to transform neurons into optogenetically programmable state and history-dependent logical transformers. Embedded processors of the system are operable to stimulate individual neurons using phase-shifted electrical and/or optical signals through a neural interface comprising a plurality of carbon nanotubes, then electrically and/or optically measure the neurons. Due to the parallelism and chemical superposition of the human brain, the implantable system is operable to establish a quantum-like processing ability using its neural interface.
Absstract of: WO2026135771A1
The present disclosure describes an analyte monitoring system that establishes backup or alternative communication channels that may be used when certain components or connections in the analyte monitoring system become unavailable. The analyte monitoring system may form direct connections between components of the analyte monitoring system and/or select replacement devices when certain components or connections become unavailable.
Absstract of: WO2026133717A1
According to the present invention, an information processing device that processes biological information about a patient who is undergoing a blood purification treatment has a computation unit that acquires the biological information on the basis of a detection signal from a biological sensor, an output unit that outputs the biological information and selection information for allowing a provider of the blood purification treatment to select whether the biological information is valid data that is to be treated as correct, an input unit into which acceptability information that indicates the details of the selection is inputted, a determination unit that determines whether the biological information is valid data on the basis of the acceptability information, and a storage unit that stores the biological data as valid data when the determination unit has determined that the biological data is valid data. (Selected drawing: figure 3)
Absstract of: US20260180665A1
Methods and systems for controlling an antenna array of an automated medicament delivery device are disclosed. The method includes causing the antenna array to transition between multiple array configurations. The multiple array configurations are chosen from among configurations that vary at least one characteristic of a signal emitted or received by one or more antennas of the antenna array, configurations that vary an activation status of the plurality of antennas, and configurations that vary a combination of the at least one characteristic of a signal and an activation status of the plurality of antennas. The method also includes measuring a power of a received signal for each configuration of the multiple array configurations of the antenna array. The method further includes selecting an array configuration of the multiple array configurations based at least in part on results of the measuring and setting the antenna array to the array configuration selected.
Absstract of: WO2026129047A1
A method for evaluating a dental preparation for a dental restoration is disclosed. A relevant point cloud is assembled from a dental preparation point cloud. A trained inference model, which may include a Dynamic Graph Convolutional Neural Network and a transformer-based encoder-decoder, predicts an inference cloud from the relevant point cloud. A dental preparation score is computed from the inference cloud. The score may include components such as scan quality, margin line, undercut, thickness, occlusal fit, taper, corner-rounding, gap analysis, contact area, gingival proximity, alignment, and abutment spacing. Inferences may be refined using spline fitting, outlier removal, and clearance analysis without necessarily generating a restoration mesh. The preparation may be classified as acceptable or not, and actions to improve the preparation may be suggested. A non-transitory computer-readable medium, a system, and a device configured to perform the method and display color-coded risk indicators are also disclosed.
Absstract of: US20260174575A1
A method of manufacturing a custom cranial remodeling orthosis device for an infant's deformed head includes the step of receiving a head shape digital file corresponding to the deformed head. The method also includes processing the head shape digital file to generate a modified shape data file. The modified shape defines hold areas on the deformed head where head growth is to be constrained and growth areas where head growth is to occur. The method further includes processing the modified shape digital file to produce an extra growth room shape data file comprising one or more extra growth room areas contiguous with corresponding one or more of the growth areas. The method further includes utilizing the extra growth room head shape data file to manufacture a modified shape with extra growth room and utilizing the modified shape with extra growth room to manufacture said custom cranial remodeling orthosis device.
Absstract of: US20260174576A1
A head model for thermoforming a cranial remodeling orthosis device to shape an infant's deformed head shape as the infant's head grows comprises a head shape surface used to define the inner surface of the cranial remodeling orthosis device. The head shape surface is derived from a three-dimensional data file representing the deformed head shape modified to a modified head shape. The head shape surface has first areas corresponding to hold areas of the cranial remodeling orthosis device where growth of the infant's head is held or restrained. The head shape surface has one or more second’ areas where the cranial remodeling orthosis device is to provide growth room for the infant's head. The one or more second areas extend radially outward from the modified head shape to provide extra growth room.
Absstract of: WO2026134694A1
According to the present embodiments, a customizable lightweight prosthetic leg frame, a prosthetic leg comprising same, and a method for manufacturing same can be provided, the customizable lightweight prosthetic leg frame having improved fidelity of healthy-side lower limb simulation and enabling a reduction in the number and weight of components due to the integrally designed components.
Absstract of: WO2026132771A1
Aspect and embodiments relate to a tissue mimicking material, a clinical phantom including a tissue mimicking material and a method of manufacture of a tissue mimicking material. One aspect provides a tissue mimicking material comprising: an elastomeric solid foam. The foam comprises gas pockets dispersed in an elastomeric material matrix and a liquid lubricant arranged within the gas pockets of the elastomeric solid foam. Aspects and embodiments recognise that a self lubricating tissue mimicking material provides a mechanism to emulate particular in vivo mammalian tissues. The modified foam material in accordance with aspects has various physical properties and characteristics which can be tuned or refined to simulate the characteristics of a mammalian tissue which the foam is intended to mimic.
Absstract of: KR20260096892A
본 발명은 족압분석 기능을 갖는 자세교정 인솔 제공서비스시스템 및 그 방법에 관한 것으로, 사용자인솔에 설치되되, 상기 사용자인솔에 가해지는 족압을 측정하여 측정된 족압데이터를 전송하는 족압센서장치; 맞춤형인솔제공서비스에 등록을 요청하고, 상기 족압센서장치를 통해 전송된 상기 족압데이터를 기 설정된 기간동안 수집하여 전송하는 사용자단말기; 상기 사용자단말기의 요청에 따라 상기 맞춤형인솔제공서비스를 등록하고, 상기 사용자단말기로부터 전송되는 상기 족압데이터에 따라 맞춤형 인솔 3D 모델링을 수행한 후에, 상기 맞춤형 인솔 3D 모델링에 대응하는 모델링데이터를 전송하는 맞춤형인솔제공서비스서버; 및 상기 맞춤형인솔제공서비스서버로부터 전송되는 상기 모델링데이터에 따라 맞춤형 인솔을 제작하여 제공하는 3D프린팅장치;를 포함함으로써, 사용자의 신발에 적용할 수 있는 맞춤형 인솔을 효과적으로 제공할 수 있고, 족압데이터에 대한 지속적인 모니터링을 통해 지속적인 자세교정을 수행하여 올바른 보행습관을 효과적으로 유도할 수 있다.
Absstract of: WO2026134948A1
The present invention relates to an apparatus and a method for performing a dementia test on the basis of non-face-to-face oral questions and answers. Dementia test request data and personal information are collected from user terminals, and administrative district and medical institution jurisdiction information is generated on the basis of originating location information. Accordingly, a person who wants a dementia test can conveniently perform a non-face-to-face dementia test at a desired time and place without having to visit a dementia test center or medical institution in person, thereby improving the convenience of the dementia test.
Absstract of: US20260175519A1
Methods and systems for designing and fabricating an additively manufactured object with dynamic printing resolutions are provided. In some embodiments, a method includes receiving a digital representation of a dental appliance, where the dental appliance includes a plurality of appliance portions. The method can also include determining a first printing resolution for a first appliance portion of the plurality of appliance portions. The method can also include determining a second printing resolution for a second appliance portion of the plurality of appliance portions, where the second printing resolution is lower than the first printing resolution. The method can further include generating instructions for fabricating the dental appliance via an additive manufacturing process.
Absstract of: US20260174526A1
0000 The prosthetic screw is for securing dental or bone-implant prosthetics to anchors, such as multi-unit abutments (MUAs). The screw includes a body with a threaded bottom portion for attachment, a head portion at the top for tool engagement, and a midsection with a curved transition profile. This curved profile eliminates right angles, evenly distributes vertical clamping forces, and reduces stress on the prosthetic, enhancing durability. The design accommodates prosthetics made from materials such as zirconia, PMMA, 3D printable photopolymer resin, and titanium, with thread sizes including M1.4, M1.6, and M1.72. The head's larger diameter facilitates secure attachment and stress management. The screw ensures reliable attachment, stress moderation, and extended functionality in dental and bone-implant systems.
Absstract of: WO2026131867A1
Here, the inventors propose a scaffold-driven approach, based on a 3D structured hydrogel polysaccharide membrane. The membrane is structured by freeze-drying to meet with the outer blood-retinal barrier (oBRB) structural requirements, namely a non-porous side to grow the retinal pigment epithelial (RPE) cells and, an inner 3D porous network for the choroidal vascularization, within the physiological thickness. A functional oBRB 3D model was obtained by cultivating RPE cells on top of the membrane, and retinal endothelial cells (EC) supported by retinal pericytes (PC) in the porous network. The inventors' approach offers a mono-bloc, easy-to-use, off-the shelf and biocompatible membrane for the modelling of a functional oBRB tissue. Thus, the present invention relates to porous scaffolds for engineering micro-structured biomimetic material for vascularized retinal epithelium.
Absstract of: WO2026135477A1
The present invention describes a detection and image reconstruction system based on microwave radar technology, designed mainly to detect breast abnormalities. The system comprises a set of emitting and receiving transducers. The signals reflected by the tissue are processed using algorithms such as delay and sum (DAS) and delay, multiply and sum (DMS), applied iteratively, which significantly improves image resolution, reconstruction and quality.
Absstract of: WO2026136679A1
Methods of laser printing include xerographic printing, printing via patterns of electrostatic charge, and/or laser printing onto a substrate with a dry mixed silk fibroin toner to produce a printed article. The dry mixed silk fibroin toner is formed by dry mixing a silk fibroin powder with a pigment powder and/or a dye powder. Laser printing can also be with a silk fibroin biotoner powder formed by mixing a silk fibroin powder and an enzyme solution, and optionally a pigment powder and/or a dye powder, to form a biotoner solution, wherein the biotoner solution is spray dried to form the silk fibroin biotoner powder. Laser printing cartridges may be loaded with a dry mixed silk fibroin toner or a silk fibroin biotoner powder.
Absstract of: US20260179175A1
0000 A computer-implemented method includes obtaining, via a processing system comprising one or more processors, a three-dimensional (3D) coronary tree segmented from computed tomography (CT) cardiac scan data of a subject, wherein the 3D coronary tree is labeled. The computer-implemented method also includes obtaining, via the processing system, a standardized two-dimensional (2D) coronary base schematic representation of a generic coronary tree. The computer-implemented method further includes modifying, via the processing system, the standardized 2D coronary base schematic representation of the generic coronary tree based on the 3D coronary tree to generate a standardized 2D coronary personalized schematic representation of a coronary tree of the subject.
Absstract of: WO2026130889A1
The present invention relates to an implantable medical device (1), comprising: an electronic circuit (2), a housing (3) accommodating the electronic circuit (2), and a three-dimensional electrically insulating body (4) carrying the electronic circuitry (2) and forming a portion of the housing (3).
Absstract of: WO2026135398A1
The present invention relates to the field of bioprinting and biotechnology, and to a system and method capable of improving quantitative dispensing accuracy through closed loop control using real-time weight feedback for hydrogel bioinks having viscoelasticity and shear thinning characteristics, and integrally performing multi-well dispensing and cell maintenance processes by robotic arm-based automation.
Absstract of: US20260179772A1
The present disclosure provides systems and methods for predicting the health state of cats, e.g., renal health. The method can include obtaining load data over time from interactions of a cat with a litter box, e.g., a smart litter box system, and using the load data in conjunction with a machine learning model with feature recognition of at least one feature based on the load data that indicates compromised health. The method can also include predicting the compromised renal health of the cat is with at least about 75% renal precision using at least a 0.5 probability threshold based on the feature recognition of the at least one feature.
Nº publicación: WO2026133239A1 25/06/2026
Applicant:
POLBIONICA SPOLKA AKCYJNA [PL]
POLBIONICA SPOLKA AKCYJNA
Absstract of: WO2026133239A1
A method for obtaining decellularized extracellular matrix of the pancreas, that it comprises the following steps, in which: the pancreas is incubated in a disinfecting solution, advantageously containing betadine at a concentration of 2% (v/v), then in a solution with an antimicrobial agent, advantageously streptomycin at a concentration of 0.01% (w/v), and then frozen; the pancreas, warmed to a temperature of 4°C ± 2°C, is subjected to homogenization in a PBS solution and 5 mM EDTA-Na2 in a 3: 1 ratio, and the homogenized material is centrifuged, after which the hydrophobic fat phase is removed; the material is suspended in a solution of NaCl at a concentration of 0.5 M + 5 mM EDTA-Na2 (pH = 7.4), and then subjected to mixing, after which the material is filtered; the material is immersed in a PBS solution and incubated, then sieved, and the sieved material is mechanically minced; the material is immersed in a PBS solution with 0.01% (w/v) streptomycin and incubated, then sieved, and the sieved material is mechanically minced; the material is immersed in a PBS solution with 0.01% (w/v) streptomycin and incubated for 2 hours at 4°C ± 2°C, the step being repeated at least twice, and the sieved material is mechanically minced after each filtration; the obtained extracellular matrix is sieved, frozen, and then subjected to lyophilization and mechanical milling.