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Solicitudes publicadas en los últimos 30 días / Applications published in the last 30 days
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THREE-DIMENSIONAL PRINTING COMPOSITION COMPRISING METHACRYLATED CHITOSAN

Publication No.:  WO2025193112A1 18/09/2025
Applicant: 
POLBIONICA S A [PL]
FUND BADAN I ROZWOJU NAUKI [PL]
POLBIONICA S.A,
FUNDACJA BADAN I ROZWOJU NAUKI
WO_2025193112_PA

Absstract of: WO2025193112A1

The invention relates to a three-dimensional printing composition comprising a dECM hydrogel-based biomaterial, a hydrogel made of methacrylated PBS biopolymer derivatives with a radical polymerisation photoinitiator, a methacrylated chitosan solution in 1% acetic acid, neutralised to a final concentration of 3.1 mg/ml in the biomaterial, and/or a chitosan solution in 2% acetic acid, neutralised to a final concentration of 1.4 mg/ml in the biomaterial.

IMPLANT SYSTEM AND METHOD FOR JOINT FUSION

Publication No.:  US2025288331A1 18/09/2025
Applicant: 
ORTHOFIX US LLC [US]
Orthofix US LLC
US_2025288331_PA

Absstract of: US2025288331A1

Implant systems and methods treatment of a joint include a distal portion, a middle portion, and a proximal portion. The distal portion may include a thread having a first thread minor, a first thread major, and a first pitch. The distal portion also may have a reverse cut, helical fenestration formed through the thread. The middle portion may be devoid of threads and may include a porous outer surface structure to promote bony integration, the porous outer surface structure having a leading end and a trailing end, with the leading end having a diameter larger than the first thread minor. The proximal portion may include a proximal thread having a second thread minor, a second thread major, and a second pitch. The second thread minor may be substantially the same width as the trailing end of the middle portion.

Method and Apparatus for Cutting Three-dimensional Tooth Model

Publication No.:  US2025288399A1 18/09/2025
Applicant: 
GUANGZHOU HEYGEARS IMC INC [CN]
GUANGZHOU HEYGEARS IMC. INC
US_2025288399_PA

Absstract of: US2025288399A1

A method and apparatus for cutting a three-dimensional tooth model are provided. The method includes: obtaining a two-dimensional projection image of a three-dimensional tooth model, and recognizing the two-dimensional projection image to obtain a plurality of tooth regions, the tooth regions corresponding one to one to teeth; determining original seed points corresponding to the plurality of tooth regions in the three-dimensional tooth model; expanding the original seed points within a preset range to obtain target seed points of the teeth in the three-dimensional tooth model; and cutting the three-dimensional tooth model based on the target seed points of the teeth to obtain cut teeth.

SACROPELVIC FUSION IMPLANT SYSTEM FOR PROVIDING A FOUNDATION FOR SPINOPELVIC FIXATION CONSTRUCTS IN ADULT SPINAL DEFORMITY SURGERY

Publication No.:  US2025288424A1 18/09/2025
Applicant: 
JCBD LLC [US]
JCBD, LLC
US_2025288424_PA

Absstract of: US2025288424A1

A method of surgically treating a patient suffering from severe pain and disability of the low back and buttock by stabilizing the patient's spinal column to their pelvis with an implant system including surgical tools and an implant designed to prevent movement between the sacrum and the ilium while being able to attach to a spinal fusion rod which connect to pedicle screws implanted in the bones of the spine of the patient in order to offer lasting relief of the patient's symptoms. The system is designed to address complications in adult spinal deformity by optimizing spinopelvic fixation vis-à-vis the unique biomechanics of the SI joint. The sacropelvic system is a surgical solution which provides an additively manufactured implant at the base of the spine employing an S2AI trajectory while utilizing assisting technologies including surgical navigation and intraoperative neurophysiological monitoring.

3D PRINTED STRUCTURALLY SOUND PROSTHETIC SOCKET

Publication No.:  US2025288423A1 18/09/2025
Applicant: 
PREC VALVE & AUTOMATION INC [US]
Precision Valve & Automation, Inc
US_2025288423_PA

Absstract of: US2025288423A1

A method for 3D printing a prosthetic socket from a digital model, including printing a solid wall perimeter of the prosthetic socket with a width achieved in a single pass of a printing nozzle, and forming a plurality of stiffener elements proximate a bottom end of the prosthetic socket, as a function of the printing the solid wall perimeter, is provided. Also provided is a 3D printed prosthetic socket including an upper portion, a lower portion configured to be attached to a prosthetic pylon, and a plurality of stiffener elements radially extending from the lower portion, wherein the upper portion, the lower portion, and the plurality of stiffener elements are printed as a solid wall construction comprised of a printing material deposited using only a single pass of a printing nozzle.

COLLAPSIBLE INNER FLOW CONTROL COMPONENT FOR SIDE-DELIVERABLE TRANSCATHETER HEART VALVE PROSTHESIS

Publication No.:  EP4617061A2 17/09/2025
Applicant: 
VDYNE INC [US]
Vdyne, Inc
EP_4617061_PA

Absstract of: EP4617061A2

A side-deliverable prosthetic heart valve includes an outer frame and a flow control component. The outer frame defines a central channel that extends along a central axis. The flow control component is disposed within the central channel and coupled to the outer frame. The flow control component has a set of leaflets mounted within an inner frame. The prosthetic valve is configured to be folded along a longitudinal axis and compressed along the central axis to place the prosthetic valve in a compressed configuration for delivery via a delivery catheter. The longitudinal axis is substantially parallel to a lengthwise axis of the delivery catheter when disposed therein. The prosthetic valve transitions to an expanded configuration when released from the delivery catheter. The flow control component elastically deforms from a substantially cylindrical configuration to a substantially flattened configuration when the prosthetic valve is placed in the compressed configuration.

複合生体材料

Publication No.:  JP2025134759A 17/09/2025
Applicant: 
スパイダーワートインク.
JP_2025134759_A

Absstract of: MX2021013857A

Provided herein are composite scaffold biomaterials including two or more scaffold biomaterial subunits, each including a decellularized plant or fungal tissue from which cellular materials and nucleic acids of the tissue are removed, the decellularized plant or fungal tissue having a 3-dimensional porous structure, the two or more scaffold biomaterial subunits being assembled into the composite scaffold biomaterial and held together via gel casting using a hydrogel glue; via complementary interlocking geometry of the two or more scaffold biomaterial subunits; via guided assembly based biolithography (GAB); via chemical cross-linking; or any combinations thereof. Methods for producing such scaffold biomaterials, as well as methods and uses thereof, are also provided.

LOAD-CARRYING ROD

Publication No.:  EP4615352A1 17/09/2025
Applicant: 
SPINESAVE AG [CH]
Spinesave AG
WO_2024100147_PA

Absstract of: WO2024100147A1

A load-carrying rod (1) for an implant system has a structure of individual interconnected solidified droplets (4) so that the transitions from one droplet to another act as crack stoppers in the event of a crack.

A DETACHABLE PRINTHEAD FOR A BIOPRINTER AND A BIOPRINTER

Publication No.:  EP4615676A1 17/09/2025
Applicant: 
INVENTIA LIFE SCIENCE PTY LTD [AU]
Inventia Life Science Pty Ltd
KR_20250125977_PA

Absstract of: AU2023377822A1

A detachable printhead for a bioprinter is disclosed, the detachable printhead comprising a body, removably attachable to a fixed portion of the bioprinter; a dispensing system, supported by the body; one or more reservoirs, for holding one or more biomaterials, in fluid communication with the dispensing system, supported by the body; and a coupling for attaching to the fixed portion of the bioprinter, the coupling including an interface for operating the dispensing system.

DYNAMIC HYDROGEL COMPOSITIONS

Publication No.:  EP4615531A1 17/09/2025
Applicant: 
UNIV LELAND STANFORD JUNIOR [US]
The Board of Trustees of the Leland Stanford Junior University
CN_120548199_PA

Absstract of: AU2023375461A1

Compositions and methods for delivery of therapeutic agents to an individual in need thereof, for prevention/reduction of tissue adhesion, and for 3D printing are disclosed herein. In some embodiments, the composition comprises octadecyl modified hydroxypropyl methylcellulose (HPMC-C18) and a surfactant or cyclic polysaccharide, wherein the composition is a hydrogel that exhibits dynamic properties.

光造型用树脂组合物

Publication No.:  CN120647849A 16/09/2025
Applicant: 
可乐丽则武齿科株式会社
CN_120647849_A

Absstract of: US2022371264A1

The present invention provides a resin composition for stereolithography that enables easy stereolithographical fabrication; and that can produce a cured object having desirable strain recovery, desirable toughness, and desirable water resistance. The present invention relates to a resin composition for stereolithography comprising a polymerizable compound (A) whose homopolymer has a glass transition temperature (Tg) of 37° C. or higher; and a photopolymerization initiator (B), and having a tan δ at 37° C. of 0.3 or less after cure.

一种3D打印生物墨水及其制备方法和应用

Publication No.:  CN120643748A 16/09/2025
Applicant: 
中国科学院苏州纳米技术与纳米仿生研究所
CN_120643748_PA

Absstract of: CN120643748A

本发明提供一种3D打印生物墨水及其制备方法和应用。所述3D打印生物墨水包括如下组分:甲基丙烯酸酐化明胶、氧化透明质酸、羧甲基壳聚糖和2‑甲基丙烯酰氧乙基磷酸胆碱。本发明通过对3D打印生物墨水的具体组成进行设计,制备得到了打印性能好、力学强度好、电传导性能好、打印后细胞存活率高的3D打印生物墨水,进而制备得到了细胞‑支架相互作用较强的3D打印支架,可用于制备皮肤损伤修复材料。

微结构的增材制造

Publication No.:  CN120659679A 16/09/2025
Applicant: 
皇家飞利浦有限公司
CN_120659679_PA

Absstract of: WO2024165390A1

The invention relates to a method for additive manufacturing of a microstructure (10) for selective transmission of X-ray or gamma-ray radiation. The method includes depositing (110) a layer of powder on a build plate or on a layer from at least one previous manufacturing step on the build plate, wherein the layer of powder comprises a high-Z material powder. Furthermore, the method includes selectively melting (120) and solidifying the powder to form septa wall structures (20) by scanning an electron beam in a spot sequence on the layer of powder to sequentially expose a plurality of spots (40) on the layer of powder to an electron beam spot. A size of the electron beam spot is at most 150 μm in diameter, preferably at most 75 μm in diameter, and more preferably at most 50 pm in diameter. The high-Z material powder comprises a high-Z material having an atomic number Z of at least 40, and preferably at least 70. The invention also relates to a microstructure for selective transmission of X-ray or gamma-ray radiation, which microstructure has been obtained by the method, and to an imaging component comprising such microstructures. The invention also relates to a method for manufacturing an imaging component.

三维光造型用固化性组合物及其制造方法、三维光造型物的制造方法以及牙科用修复物的制造方法

Publication No.:  CN120659706A 16/09/2025
Applicant: 
株式会社德山齿科
CN_120659706_A

Absstract of: AU2024218051A1

The present invention provides a curable composition for three-dimensional stereolithography, the curable composition being used in a vat photopolymerization method and containing 100 parts by mass of a polymerizable monomer component (A), 40 parts by mass to 400 parts by mass of an inorganic filler (B) that is composed of a single kind or plural kinds of inorganic particulate matter, and 0.01 part by mass to 5 parts by mass of a photopolymerization initiator (C), wherein: 80% or more of all primary particles that constitute the inorganic filler (B) have a particle diameter of 0.05 µm to 5.0 µm; and a sample, which is formed of this curable composition for three-dimensional stereolithography and has a thickness of 0.5 mm, has a transmittance of 1.00% to 50.00% with respect to activation light. The present invention also provides a method for producing this curable composition for three-dimensional stereolithography. The present invention also provides a method for producing a three-dimensional stereolithographic model and a method for producing a dental restoration, each using this curable composition for three-dimensional stereolithography.

Chamber with a flow system for bioprinting and culturing tissue models

Publication No.:  PL132037U1 15/09/2025
Applicant: 
POLBIONICA SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA [PL]
POLBIONICA SP\u00D3\u0141KA Z OGRANICZON\u0104 ODPOWIEDZIALNO\u015ACI\u0104

Absstract of: PL132037U1

Przedmiotem zgłoszenia jest komora z układem przepływowym do biodrukowania i hodowli modeli tkankowych zawierająca: korpus (1) komory z otworem środkowym przesłoniętym szkiełkiem dolnym (2), przykryty z wierzchu pokrywą (3) zaopatrzoną w otwór środkowy przesłonięty szkiełkiem górnym (5), przy czym pomiędzy korpusem (1) komory i pokrywą (3) komory znajduje się silikonowa uszczelka obwodowa (4), gdzie korpus (1) komory na swoich dwóch przeciwległych końcach zaopatrzony jest w złącza (8) z kanałami łączącymi (10) zapewniającymi połączenie płynowe z objętością roboczą komory wyznaczoną przez ściany wewnętrzne korpusu (1) komory i pokrywy (3), uszczelkę obwodową (4) i powierzchnie wewnętrzne szkiełka dolnego (2) i szkiełka górnego (5) skierowane ku sobie nawzajem, gdzie układ przepływowy jest utworzony przez złącza (8) wraz z kanałami łączącymi (10) oraz objętość roboczą komory zawartą pomiędzy nimi; oraz obudowę zewnętrzną komory złożoną z ramki dolnej (6) i ramki górnej (7), przy czym korpus (1) komory i pokrywa (3) komory wraz z elementami zawartymi pomiędzy nimi są zamknięte pomiędzy ramką dolną (6) i ramką górną (7) obudowy zewnętrznej, które połączone są ze sobą rozłącznie.

Casing that strengthens and seals the bioprinted tissue model

Nº publicación: PL132035U1 15/09/2025

Applicant:

POLBIONICA SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA [PL]
POLBIONICA SP\u00D3\u0141KA Z OGRANICZON\u0104 ODPOWIEDZIALNO\u015ACI\u0104

Absstract of: PL132035U1

Obudowa wzmacniająca i uszczelniająca biodrukowany model tkankowy, składająca się z modułu wewnętrznego oraz zewnętrznego, moduł wewnętrzny zawiera: podstawę składającą się z dna w kształcie prostokąta o zaokrąglonych rogach i ścian bocznych, przy czym na jednej z krótszych ścian bocznych, po stronie zewnętrznej znajdują się dwa elementy mające kształt tulei, usytuowane obok siebie; średnica elementów jest mniejsza niż wysokość ściany bocznej; i pokrywę składającą się z powierzchni górnej w kształcie prostokąta o zaokrąglonych rogach i ścian bocznych, przy czym na jednej z krótszych ścian bocznych znajdują się dwa otwory o kształcie ściętego koła, odpowiadające wielkością elementom w kształcie tulei, przy czym pokrywa na całej górnej powierzchni posiada perforacje, przy czym po złożeniu podstawy i pokrywy ściany boczne podstawy znajdują się wewnątrz modułu, a ściany boczne pokrywy znajdują się na zewnątrz modułu wewnętrznego, wysokość ścian bocznych jest dobrana w taki sposób, aby po złożeniu ściany zewnętrzne zakrywały całkowicie ściany wewnętrzne, moduł zewnętrzny zawiera: pojemnik, o kształcie otwartego prostopadłościanu posiadającego zaokrąglone rogi i pokrywę zewnętrzną (8), zamykającą pojemnik (7), przy czym powierzchnia górna (P) pokrywy zewnętrznej (8) posiada dwa otwory (9), które rozmiarem i rozmieszczeniem odpowiadają elementom znajdującym się w module wewnętrznym, p

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