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LastUpdate Updated on 15/09/2026 [08:14:00]
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HYPERIMMUNE GLOBULIN COMPOSITIONS FOR USE IN THE TREATMENT OF COVID-19

Publication No.:  US20260234221A1 13/08/2026
Applicant: 
GRIFOLS WORLDWIDE OPERATIONS LTD [IE]
Grifols Worldwide Operations Limited
US_20260234221_A1

Absstract of: US20260234221A1

The disclosure relates to a pharmaceutical composition comprising human plasma-derived polyclonal, anti-SARS-CoV-2 hyperimmune globulins and to said pharmaceutical composition for use in the treatment of a SARS-CoV-2 Omicron variant infection. The disclosure also relates to a method for the preparation of a polyclonal, hyperimmune globulin composition anti-SARS-CoV-2.

ANTISENSE MOLECULES AND THEIR USES FOR THE TREATMENT OF CORONAVIRUS INFECTION, IN PARTICULAR THE TREATMENT OF COVID-19 RELATED TO SARS-COV-2 INFECTION

Publication No.:  US20260234629A1 13/08/2026
Applicant: 
INSTITUT NATIONAL DE RECH POUR LAGRICULTURE LALIMENTATION ET L\u2019ENVIRONNEMENT [FR]
INSTITUT NAT DES SCIENCES ET INDUSTRIES DU VIVANT ET DE LENVIRONNEMENT [FR]
UNIV DE VERSAILLES SAINT QUENTIN EN YVELINES [FR]
ECOLE NAT VETERINAIRE DALFORT [FR]
UNIV ANDRES BELLO [CL]
Institut National De Recherche Pour L'Agriculture, L'Alimentation Et L\u2019Environnement
INSTITUT NATIONAL DES SCIENCES ET INDUSTRIES DU VIVANT ET DE L'ENVIRONNEMENT
UNIVERSITE DE VERSAILLES SAINT-QUENTIN-EN-YVELINES
\u00C9COLE NATIONALE VETERINAIRE D'ALFORT
UNIVERSIDAD ANDRES BELLO
US_20260234629_A1

Absstract of: US20260234629A1

0000 The present invention relates to a new antisense oligonucleotide, a pharmaceutical composition comprising it and their use for preventing or treating infection by coronavirus, especially by SARS-CoV-2 virus which causes the infection disease COVID-19.

APTAMER BASED DETECTION OF SARS-COV-2 INFECTION

Publication No.:  US20260235601A1 13/08/2026
Applicant: 
COUNCIL OF SCIENT & INDUSTRIAL RESEARCH [IN]
COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
US_20260235601_A1

Absstract of: US20260235601A1

0000 The present invention relates to development of novel ssDNA aptamers comprising the oligonucleotide sequence that detect receptor-binding domain (RBD) of Severe Acute Respiratory Syndrome Corona virus (SARS-nCOV-2) infection. The ssDNA aptamers of the present invention may be used in lateral flow assays, electrochemical sensors and calorimetric sensors using gold nanoparticles. The present invention also relates to an analytical composition comprising said ssDNA aptamers. Further, the present invention also relates to a diagnostic kit for detecting RBD of SARS-nCoV-2.

PEDIATRIC SARS-COV-2 ANTIBODIES AND USES THEREOF

Publication No.:  US20260234224A1 13/08/2026
Applicant: 
VANDERBILT UNIV [US]
VANDERBILT UNIVERSITY
US_20260234224_A1

Absstract of: US20260234224A1

The present disclosure relates to antibodies and uses thereof for treating, preventing, and detecting coronavirus infection.

Plant-Based Compositions And Methods For Modulation of Inflammatory Response Post Viral Infection

Publication No.:  US20260232749A1 13/08/2026
Applicant: 
VDF FUTURECEUTICALS INC [US]
VDF Futureceuticals, Inc.
US_20260232749_A1

Absstract of: US20260232749A1

A polyphenol-rich composition is orally administered to alleviate a sign or symptom of a post-viral syndrome, and preferably post-COVID syndrome. Most typically, the composition comprises at least 50 wt % total catechins, at least 20 wt % total chlorogenic acids, and optionally up to 30 wt % total supplemental antioxidants. The composition may be formulated from a green coffee bean extract, a green tea extract, a turmeric extract, a tart cherry or extract thereof, a broccoli or extract thereof, and a kale or extract thereof. Notably, such compositions were effective in individuals post SARS-CoV2 infection to reduce proinflammatory cytokines and interleukins, increase NOHb, and to reduce reactive oxygen species due to mitochondrial dysfunction, iNOS activity, and NOX2 activity.

Method and Composition for the Inhalation of Hypochlorous Acid (HOCl) for Respiratory Treatment and Pathogen Elimination

Publication No.:  US20260232725A1 13/08/2026
Applicant: 
CONTRACTOR CYRUS DARIUS [US]
Contractor Cyrus Darius
US_20260232725_A1

Absstract of: US20260232725A1

0000 This invention provides a method for the therapeutic inhalation of hypochlorous acid (HOCl) to treat respiratory infections, reduce lung inflammation, and eliminate airborne pathogens in humans and animals. It describes controlled delivery of HOCl (10-50 ppm) via nebulizers, humidifiers, CPAP devices, ventilators, and direct tracheal instillation to improve oxygenation, break down mucus, and prevent secondary infections. The stabilized HOCl formulation ensures safety and efficacy, distinguishing it from surface disinfection applications. The method leverages HOCl's natural antimicrobial, anti-inflammatory, and mucolytic properties for direct respiratory treatment without toxicity or lung irritation. Applications include treating pneumonia, COVID-19, asthma, bronchitis, and ventilator-associated infections, as well as reducing airborne pathogen transmission in enclosed spaces. The invention presents a novel, non-toxic, and cost-effective approach to respiratory care, enhancing both individual treatment and public health disease mitigation.

AN ISOLATED POLYPEPTIDE OR ANTIGENIC FRAGMENT THEREOF AND ITS USES FOR DIAGNOSING OR PREDICTING A DISEASE SUCH AS LONG COVID OR POST-VAC-SYNDROME

Publication No.:  EP4789026A1 12/08/2026
Applicant: 
UNIV REGENSBURG IN VERTRETUNG DES FREISTAATS BAYERN [DE]
UNIV REGENSBURG [DE]
Universit\u00E4t Regensburg, in Vertretung des Freistaats Bayern
Universit\u00E4tsklinikum Regensburg
WO_2025073771_A1

Absstract of: WO2025073771A1

The present invention inter alia relates to an use of an isolated polypeptide or an antigenic fragment thereof, comprising a polypeptide region having at least 60% sequence identity with any one of the polypeptide sequences selected from the group consisting of SEQ ID No.: 1-11, 16-20 and 23-28; wherein the isolated polypeptide is having a length of no more than 200 contiguous amino acids for diagnosing Long COVID or Post-Vac-Syndrome, or for predicting a risk of developing Long COVID or Post-Vac-Syndrome. The present invention also relates to the isolated polypeptide or antigenic fragment thereof for use in preventing, treating or ameliorating Long COVID or Post-Vac-Syndrome., as well as to a method of detecting a presence of antibodies against SARS-CoV-2 in a subject, comprising the step of contacting a sample of said subject with at least one of the polypeptide or antigenic fragment thereof.

CORONAVIRUS SPIKE PROTEIN VARIANTS

Publication No.:  EP4790065A1 12/08/2026
Applicant: 
SHIONOGI & CO [JP]
KOTAI BIOTECHNOLOGIES INC [JP]
Shionogi & Co., Ltd
KOTAI Biotechnologies, Inc.
EP_4790065_A1

Absstract of: EP4790065A1

Coronavirus spike protein variants for use in antigens for vaccines for coronavirus infection are provided.A coronavirus spike protein variant comprising:(a) a receptor binding domain (RBD) consisting of an amino acid sequence set forth in SEQ ID NO: 1;(b) an RBD consisting of an amino acid sequence obtained by substituting, deleting, inserting, or adding one to several amino acids in the amino acid sequence set forth in SEQ ID NO: 1, and having neutralizing antibody-inducing activity against SARS-CoV-2 and SARS-CoV-1 equivalent to that of an RBD consisting of the amino acid sequence set forth in SEQ ID NO: 1; or(c) an RBD consisting of an amino acid sequence that has at least 90% sequence identity to the amino acid sequence set forth in SEQ ID NO: 1, and having neutralizing antibody-inducing activity against SARS-CoV-2 and SARS-CoV-1 equivalent to that of the RBD consisting of the amino acid sequence set forth in SEQ ID NO: 1.

Methods for treating SARS CoV-2 infections

Publication No.:  AU2026206109A1 06/08/2026
Applicant: 
GILEAD SCIENCES INC
Gilead Sciences, Inc.
AU_2026206109_A1

Absstract of: AU2026206109A1

Provided are methods for treating 2019-nCoV virus (SARS-CoV-2) infections by administering nucleosides and prodrugs thereof, of Formula I: , wherein the 1’ position of the nucleoside sugar is substituted. R¹ R¹¹¹ R¹ R³ X"" R² ul u l ¹ ²

β-LACTOGLOBULIN FOR USE AS ANTIVIRAL AGENT

Publication No.:  WO2026163139A1 06/08/2026
Applicant: 
HOVIONE FARM S A [PT]
HOVIONE - FARMACI\u00CANCIA S A
WO_2026163139_A1

Absstract of: WO2026163139A1

The present disclosure relates to the use of β-lactoglobulin in the treatment of a viral condition, wherein β-lactoglobulin is in its native protein state, wherein the viral condition is caused by a human Rotavirus strain or Coronavirus OC43. The present disclosure further relates to a pharmaceutical composition comprising β-lactoglobulin and one or more pharmaceutically acceptable excipients, wherein the pharmaceutical composition further comprises at least one additional therapeutic agent.

SULFONE-1H-PYRROLE-2-CARBOXAMIDE INHIBITORS OF SARS-COV-2 NSP14 METHYLTRANSFERASE AND DERIVATIVES THEREOF

Publication No.:  US20260226034A1 06/08/2026
Applicant: 
THE ROCKEFELLER UNIV [US]
The Rockefeller University
US_20260226034_A1

Absstract of: US20260226034A1

0000 Methods and compositions for treating SARS-CoV-2 and COVID-19 are disclosed. Sulfone-1H-pyrrole-2-carboxamides of the following formula 0000 0000 inhibit the SARS-CoV-2 PLpro/NSP3 protein and are therefore useful for treating SARS-CoV-2 and COVID-19.

ANTI-SARS-COV-2 MONOCLONAL ANTIBODY AND IMMUNOASSAY METHOD AND IMMUNOASSAY INSTRUMENT FOR SARS-COV-2 USING SAME

Publication No.:  US20260226140A1 06/08/2026
Applicant: 
DENKA CO LIMITED [JP]
Denka Company Limited
US_20260226140_A1

Absstract of: US20260226140A1

Disclosed are a monoclonal antibody capable of rapidly, simply, and highly sensitively detecting and measuring SARS-CoV-2 contained in a test sample, and an immunoassay method and immunoassay device for SARS-CoV-2 using the same. The monoclonal antibody or its antigen-binding fragment includes heavy chain CDR1-CDR3 having specific amino acid sequences and light chain CDR1-CDR3 having specific amino acid sequences. The immunoassay method for SARS-CoV-2 includes performing an immunoassay of SARS-CoV-2 utilizing an antigen-antibody reaction between this monoclonal antibody or its antigen-binding fragment and SARS-CoV-2 in a sample.

SARS-CoV-2 DETECTION METHOD AND KIT THEREFOR

Publication No.:  US20260227401A1 06/08/2026
Applicant: 
DENKA CO LIMITED [JP]
Denka Company Limited
US_20260227401_A1

Absstract of: US20260227401A1

Disclosed is a high performance anti-SARS-CoV-2 antibody and a detection reagent using it. The method of detecting SARS-CoV-2 includes detecting SARS-CoV-2 in a sample by an immunoassay method using a monoclonal antibody that specifically reacts with the N protein of SARS-CoV-2, or an antigen-binding fragment thereof. The detection kit for SARS-CoV-2 includes a monoclonal antibody that specifically reacts with the N protein of SARS-CoV-2, or an antigen-binding fragment thereof.

SARS-CoV-2 DETECTION METHOD AND KIT THEREFOR

Publication No.:  US20260227402A1 06/08/2026
Applicant: 
DENKA CO LIMITED [JP]
Denka Company Limited
US_20260227402_A1

Absstract of: US20260227402A1

0000 Disclosed is a high-performance anti-SARS-CoV-2 antibody and a detection reagent using it. The method of detecting SARS-CoV-2 includes detecting SARS-CoV-2 in a sample by an immunoassay method using a monoclonal antibody that specifically reacts with the RNA-binding domain in the N protein of SARS-CoV-2, or an antigen-binding fragment thereof. The detection kit for SARS-CoV-2 includes a monoclonal antibody that specifically reacts with the RNA-binding domain in the N protein of SARS-CoV-2, or an antigen-binding fragment thereof.

SARS-COV2 MAIN PROTEASE INHIBITORS

Publication No.:  AU2025219283A1 06/08/2026
Applicant: 
GILEAD SCIENCES INC
GILEAD SCIENCES, INC.
AU_2025219283_PA

Absstract of: AU2025219283A1

The present disclosure relates to compounds of Formula (I): and pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, useful in the treatment of treating viral infections, for example, coronaviridae infections.

COLD-ADAPTED, LIVE ATTENUATED SARS-COV-2 VACCINE

Publication No.:  US20260226425A1 06/08/2026
Applicant: 
THE UNIV OF TOKYO [JP]
WISCONSIN ALUMNI RES FOUNDATION [US]
The University of Tokyo
Wisconsin Alumni Research Foundation
US_20260226425_A1

Absstract of: US20260226425A1

An isolated nucleic acid comprising a recombinant coronavirus genome having a genetic modification that provides cold-adapted growth relative to a parent virus that is not cold-adapted and a vaccine comprising the recombinant genome and methods of using the vaccine are provided.

SARS-COV2 MAIN PROTEASE INHIBITORS

Publication No.:  AU2025218930A1 06/08/2026
Applicant: 
GILEAD SCIENCES INC
GILEAD SCIENCES, INC.
AU_2025218930_PA

Absstract of: AU2025218930A1

The present disclosure relates to compounds of Formula I and pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, useful in the treatment of treating viral infections, for example, coronaviridae infections.

SARS-COV-2 REPLICATION-DEFECTIVE VIRUS SYSTEM

Publication No.:  WO2026163027A1 06/08/2026
Applicant: 
UNIV OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION [US]
UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
WO_2026163027_A1

Absstract of: WO2026163027A1

Provided herein is a replication-defective coronavirus having in its genome a modification, wherein the modification results in a reduced expression of the M gene compared to a coronavirus lacking the modification.

HUMAN ANTIBODIES TO MIDDLE EAST RESPIRATORY SYNDROME-RELATED CORONAVIRUS (MERS-CoV) AND METHODS OF USE THEREFOR

Publication No.:  WO2026165023A1 06/08/2026
Applicant: 
VANDERBILT UNIV [US]
VANDERBILT UNIVERSITY
WO_2026165023_A1

Absstract of: WO2026165023A1

The present disclosure is directed to antibodies binding to and neutralizing Middle East Respiratory Syndrome-Related Coronavirus (MERS-CoV) and methods for use thereof.

SARS-CoV-2 DETECTION METHOD AND KIT THEREFOR

Publication No.:  US20260227400A1 06/08/2026
Applicant: 
DENKA CO LIMITED [JP]
Denka Company Limited
US_20260227400_A1

Absstract of: US20260227400A1

0000 Disclosed is a high performance anti-SARS-CoV-2 antibody and a detection reagent using it. The method of detecting SARS-CoV-2 includes detecting SARS-CoV-2 in a sample by an immunoassay method using a monoclonal antibody that specifically reacts with 301aa-319aa, 301aa-320aa, or 351aa-375aa of the amino acid sequence of the N protein of SARS-CoV-2, or an antigen-binding fragment thereof. The detection kit for SARS-CoV-2 includes a monoclonal antibody that specifically reacts with 301aa-319aa, 301aa-320aa, or 351aa-375aa of the amino acid sequence of the N protein of SARS-CoV-2, or an antigen-binding fragment thereof.

ANTI-SARS-COV-2 SPIKE (S) ANTIBODIES AND THEIR USE IN TREATING COVID-19

Publication No.:  EP4784613A2 05/08/2026
Applicant: 
NOVAVAX INC [US]
Novavax, Inc.
CN_122029189_PA

Absstract of: CN122029189A

The present invention provides antibodies that bind to the SARS-CoV-2 spike (S) protein. The invention further relates to pharmaceutical compositions, immunotherapeutic compositions and methods of using the above antibodies that bind to the SARS-CoV-2 spike (S) protein.

SARS-COV-2 ANTIBODIES AND METHODS OF USING THE SAME

Publication No.:  RS68251B1 31/07/2026
Applicant: 
ASTRAZENECA UK LTD [GB]
ASTRAZENECA UK LIMITED
RS_68251_B1

Absstract of: US20250289871A1

0000 The present disclosure provides antibodies and antigen-binding fragments thereof that specifically bind to the spike protein of SARS-CoV-2 and methods of making and using the same. The antibodies can be used, for example, in prophylaxis, post-exposure prophylaxis, or treatment of SARS-CoV-2 infection. The antibodies can also be used to detect SARS-CoV-2, e.g., an infection in subject.

CORONAVIRUS ANTIBODIES AND THERAPEUTIC USES THEREOF

Publication No.:  US20260217797A1 30/07/2026
Applicant: 
TAKEDA PHARMACEUTICAL CO LIMITED [JP]
Takeda Pharmaceutical Company Limited
US_20260217797_A1

Absstract of: US20260217797A1

Disclosed herein are antibodies that bind to coronavirus spike protein (e.g., SARS-CoV-2 spike protein), and methods of use thereof (e.g., treatment of subjects infected with SARSCoV-2).

ANTIBODY SPECIFICALLY BINDING TO IL-10 RECEPTOR AND USE THEREOF

Publication No.:  US20260217840A1 30/07/2026
Applicant: 
IUCF HYU INDUSTRY UNIV COOPERATION FOUNDATION HANYANG UNIV [KR]
IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY)
US_20260217840_A1

Absstract of: US20260217840A1

The present invention relates to an antibody specifically binding to an IL-10 receptor and use thereof. The antibody targets IL-10 signaling and has an excellent effect of suppressing cytokine storm and excessive inflammation in severe inflammatory infectious diseases, and in particular, can be effectively used in suppressing inflammatory responses in severe SARS-CoV-2 infection and fatal SFTSV infection.

TREATMENT OF CHEMOSENSORY DYSFUNCTION FROM A CORONAVIRUS INFECTION

Nº publicación: US20260216194A1 30/07/2026

Applicant:

CYRANO THERAPEUTICS INC [US]
Cyrano Therapeutics, Inc.

US_20260216194_A1

Absstract of: US20260216194A1

Disclosed herein are methods of treating a taste and smell disorder caused by a viral infection in a subject, comprising administering to the subject a phosphodiesterase inhibitor. Also disclosed herein are methods of treating taste and smell loss from COVID-19 by administering a phosphodiesterase inhibitor to a subject in need thereof.

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