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LastUpdate Updated on 21/08/2025 [07:11:00]
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Solicitudes publicadas en los últimos 90 días / Applications published in the last 90 days
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Application of dephosphorylated NDP52 protein in preparing medicine for controlling salmonella infection

Publication No.:  CN120025421A 23/05/2025
Applicant: 
EAST CHINA UNIV OF SCIENCE AND TECHNOLOGY
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CN_120025421_A

Absstract of: CN120025421A

The invention belongs to the technical field of gene engineering, and particularly relates to application of dephosphorylated NDP52 protein in preparation of salmonella infection control drugs. The technical scheme of the invention is as follows: a protein NDP52S162A with an amino acid sequence of SEQ ID No.1, a gene for coding the protein and with a nucleotide sequence of SEQ ID No.2, a recombinant vector, a transgenic cell line or a recombinant virus containing the gene, and a substance capable of realizing dephosphorylation of the NDP52 protein are provided; the invention also discloses application of the gene, the protein and a substance for realizing dephosphorylation of the NDP52 protein in preparation of salmonella infection control medicines, and experiments in mice show that the NDP52 protein and the 162-site serine dephosphorylation thereof promote removal of salmonella in the liver of the mice and play a role in controlling salmonella infection.

Salmonella identification culture medium and preparation method thereof

Nº publicación: CN120026080A 23/05/2025

Applicant:

SHENZHEN YANGGUANG LANGRUN INVEST PARTNERSHIP ENTERPRISE GENERAL PARTNERSHIP
QIAN XIAODONG
HU QIN
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CN_120026080_PA

Absstract of: CN120026080A

The invention provides a salmonella identification culture medium and a preparation method thereof. The salmonella identification culture medium comprises the following components: a basic substrate, a sugar agent, a chromogenic substrate and a selective inhibitor. The chromogenic substrate comprises sodium thiosulfate and ammonium ferric citrate. The selective inhibitor is prepared from sodium sulfite, lauryl sodium sulfate, 7-ethyl-2-methyl-4-undecyl sodium sulfate and vancomycin. According to the salmonella identification culture medium, the identification efficiency of salmonella can be effectively improved, and the identification accuracy of salmonella is improved.

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