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LastUpdate Updated on 06/08/2025 [07:19:00]
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Solicitudes publicadas en los últimos 60 días / Applications published in the last 60 days
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DEVICES, SOLUTIONS AND METHODS FOR SAMPLE COLLECTION RELATED APPLICATIONS, ANALYSIS AND DIAGNOSIS

Publication No.:  US2025189517A1 12/06/2025
Applicant: 
DNA GENOTEK INC [CA]
DNA Genotek, Inc
US_2025189517_A1

Absstract of: US2025189517A1

A solution is described for preserving cells and/or extra cellular components in naturally expressed bodily fluids (e.g. saliva, sputum, urine) for further downstream analysis and/or for diagnosis of a medical condition. The solution may be hypertonic with respect to blood. Techniques are described for enriching cells from a sample of a naturally expressed bodily fluid, and/or for analysis, e.g. to diagnose medical conditions such as cancer, obesity, infections, autism, Alzheimer disease, hetotological disorders, cardiovascular disease or disorders, diabetes, vulnerable plack, LTBI, HIV infection, COPD, ACQS.

CATABODIES AND METHODS OF USE THEREOF

Publication No.:  US2025189536A1 12/06/2025
Applicant: 
AB STUDIO INC [US]
AB Studio Inc
US_2025189536_A1

Absstract of: US2025189536A1

The present application provides methods, compositions and kits for determining SHD catabody levels in a biological sample, and for treating or preventing a protein aggregation disease (PAD) in an individual. Also provided are catabodies specifically recognizing amyloid beta (Aβ) peptides and methods of use thereof.

METHOD FOR QUANTIFYING ACTIVE OREXIN A

Publication No.:  US2025189543A1 12/06/2025
Applicant: 
EISAI R&D MAN CO LTD [JP]
Eisai R&D Management Co., Ltd
US_2025189543_A1

Absstract of: US2025189543A1

A method for quantifying active orexin A in a specimen, comprising: a step of contacting the specimen with a monoclonal antibody that recognizes the C-terminal side of orexin A to separate orexin A species; a step of digesting the separated orexin A species with a protease to obtain a peptide consisting of an amino acid sequence of SEQ ID NO: 1; and a step of performing mass spectrometry on the peptide.

BIOMARKER AND RELATED DETECTION KIT FOR ALZHEIMER'S DISEASE

Publication No.:  EP4567427A1 11/06/2025
Applicant: 
SHANGHAI RAISING PHARMACEUTICAL CO LTD [CN]
Shanghai Raising Pharmaceutical Co., Ltd
EP_4567427_PA

Absstract of: EP4567427A1

A method for distinguishing or differentially diagnosing Alzheimer's disease from other neurodegenerative diseases, comprising determining the level of TPK1 protein in a sample from a subject, wherein a decrease in the level of TPK1 protein compared to a reference value indicates that the subject has Alzheimer's disease. Methods, compositions, test strips, test cards and/or kits for distinguishing or differentially diagnosing Alzheimer's disease from other neurodegenerative diseases by detecting a biomarker, wherein the methods, compositions, test strips, test cards and/or kits can specifically diagnose Alzheimer's disease.

传感器芯片及其方法

Publication No.:  CN120121584A 10/06/2025
Applicant: 
新加坡国立大学
CN_120121584_PA

Absstract of: US2022373562A1

The present disclosure relates generally to a sensor chip and methods for the detection of an analyte. In particular, the disclosure relates to a sensor chip for detecting an analyte in a subject suffering from a neurodegenerative disease. The sensor chip comprises a conductive layer on a membrane support layer, wherein a plurality of apertures extend through the conductive layer and the membrane support layer and are arranged such that illumination of the conductive layer and/or the membrane support layer produces a surface plasmon resonance.

用于评估和治疗神经退行性疾病的蛋白质标志物

Nº publicación: CN120129834A 10/06/2025

Applicant:

香港科技大学香港神经退行性疾病中心有限公司

CN_120129834_PA

Absstract of: AU2023356443A1

Provided is a protein marker Nell-1, which is present in a person's blood sample in an amount that is correlated with neurodegenerative disorders such as Alzheimer's Disease (AD), Mild Cognitive Impairment (MCI), and Parkinson's Disease (PD). Corresponding diagnostic and treatment methods for these neurodegenerative disorders as well as kits for diagnosing or treating the neurodegenerative disorders are also provided.

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