Resumen de: CN121400487A
The invention discloses a novel anti-salmonella nano preparation CCJY as well as a preparation method and application thereof. The preparation comprises chitosan nano particles. The chitosan nanoparticle comprises cross-linked chitosan, and a lasso peptide MccJ25 and a lasso peptide MccY which are loaded on the chitosan. According to the invention, the synergistic antibacterial effect among different lasso peptides is exerted through a chemical cross-linking technology, on the basis of integrating the original antibacterial types of the lasso peptide MccJ25 and the lasso peptide MccY, the antibacterial types are expanded to serratia marcescens and enterococcus cloacae, and the broad-spectrum antibacterial effect is realized. Meanwhile, the invention further discloses a preparation method and application of the chitosan nano-particles and an anti-salmonella nano-preparation containing the chitosan nano-particles.
Nº publicación: CN121406536A 27/01/2026
Solicitante:
NORTHEAST AGRICULTURAL UNIV
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Resumen de: CN121406536A
The invention provides anti-PDCoV combined lactobacillus salivarius LSM237 and application thereof, and belongs to the technical field of microorganisms. The preservation number of the combined lactobacillus salivarius LSM237 is CCTCC (China Center For Type Culture Collection) NO: M 20252371. The probiotics are symbiotic probiotics in intestinal tracts, have the characteristics of high acid production capacity, acid resistance and bile salt resistance, have high endurance capacity to artificial gastrointestinal fluid, and can inhibit serratia marcescens, escherichia coli, staphylococcus aureus and salmonella typhimurium. The combined lactobacillus salivarius LSM237 has a remarkable anti-PDCoV effect, the anti-PDCoV infection capability of piglets can be improved, and clinical symptoms caused by PDCoV infection can be relieved. The combined lactobacillus salivarius LSM237 can regulate the immune system of a body and maintain the balance of intestinal flora of the body, can provide an application basis for developing a novel micro-ecological viable bacterium preparation for treating viral infection diseases of piglets, and can replace antibiotics to be applied to the micro-ecological viable bacterium preparation.