Tecnoloxía para a monitorización e control de Diabetes

NEEDLE RETRACTION ASSEMBLY FOR A DEVICE FOR DELIVERING INSULIN

Resumen de: WO2024173658A2

An infusion system comprising: a device configured to deliver medication to a user through an infusion catheter, wherein the device includes a housing configured to receive the infusion catheter and to maintain the infusion catheter in the user after insertion; and a detachable activation mechanism for deploying the device for delivering medication to the user, wherein the detachable activation mechanism comprises a trigger and a retraction mechanism that includes an introducer needle for introducing the infusion catheter into the user, wherein the detachable activation mechanism is configured to releasably connect to the housing, wherein the detachable activation mechanism is configured to insert the infusion catheter into the user, automatically release the detachable activation mechanism from the housing responsive to activation of the trigger and automatically retract the introducer needle into the needle retraction assembly to shield the needle upon the automatic release of the detachable activation mechanism.

METHOD OF OUTPUTTNG BLOOD GLUCOSE DATA

Resumen de: AU2025202475A1

One embodiment may provide a method of outputting blood glucose data including obtaining biometric information in response to an advertisement transmitted by a sensor transmitter, generating the biometric information as output, in the case that a communication failure occurs, indicating a data gap during a period of the communication failure, and if the communication failure is resolved, filling the data gap during a period from a time point when the communication failure is resolved to one advertisement which arrives after the communication failure is resolved. One embodiment may provide a method of outputting blood glucose data including obtaining biometric information in response to an advertisement transmitted by a sensor transmitter, generating the biometric information as output, in the case that a communication failure occurs, indicating a data gap during a period of the communication failure, and if the communication failure is resolved, filling the data gap during a period from a time point when the communication failure is resolved to one advertisement which arrives after the communication failure is resolved. pr p r c o m m u n i c a t i o n f a i l u r e i s r e s o l v e d @ pr p r

MANUAL INSULIN PUMP CONFIGURATION

Resumen de: WO2025259242A1

The invention relates to a manually controlled manual insulin pump configuration suitable for use by diabetic individuals who have to inject with an insulin pen before each meal or high blood sugar correction dose.

OPTICAL SHORT-WAVE INFRARED SENSOR FOR BIOMEDICAL APPLICATIONS

Resumen de: WO2025258837A1

The present invention relates to an optical sensor and a wearable device comprising the same for non-invasively determining a concentration of blood components, for example, blood glucose and glycated hemoglobin levels. The optical sensor comprises an emitter configured to emit short-wave infrared (SWIR) radiation, an insulator with a channel transparent to the SWIR radiation, the emitter being disposed on top of the insulator and configured to emit the radiation into a biological tissue through the transparent channel, an optical concentrator made from a material with a refractive index of 1.7 or more, and a photodetector disposed in an upper part of the optical concentrator. The invention provides the possibility of non-invasive, instant or continuously monitoring of blood glucose and glycated hemoglobin levels. 2 indep. claims and 13 dep. claims, 15 figs., 2 tables.

METHOD OF DISPLAYING COMMUNICATION STATUS IN GLUCOSE MONITORING SYSTEM

Resumen de: US2025380912A1

One embodiment may provide a method of displaying a communication status in a glucose monitoring system, the method including displaying a communication status of a communication module in a terminal configured to transmit and receive data with a sensor transmitter, when the communication module is turned off, delaying a display of a communication module turn-off for one period of time by the terminal, and if the turn-off of the communication module persists for the one period of time, displaying the communication module turn-off.

METHOD OF PROVIDING NOTIFICATION OF SIGNAL LOSS IN GLUCOSE MONITORING SYSTEM

Resumen de: AU2025201860A1

One embodiment may provide a method of providing a notification of signal loss in a glucose monitoring system, the method including, when a communication failure occurs between a terminal and a sensor transmitter, delaying a signal loss notification for a first period of time by the terminal, when the communication failure persists for the first period of time, further determining whether signal loss persists for a second period of time by the terminal, when the signal loss persists for the second period of time, generating the signal loss notification by the terminal, and outputting, by the terminal, the signal loss notification to a user. One embodiment may provide a method of providing a notification of signal loss in a glucose monitoring system, the method including, when a communication failure occurs between a terminal and a sensor transmitter, delaying a signal loss notification for a first period of time by the terminal, when the communication failure persists for the first period of time, further determining whether signal loss persists for a second period of time by the terminal, when the signal loss persists for the second period of time, generating the signal loss notification by the terminal, and outputting, by the terminal, the signal loss notification to a user.20 ar a r t o a u s e r Sensor module Sensor communicator Sensor controller Sensor storage 120 130 140 Outputter Communicator Controller Storage 220 230 240 ar a r

METHOD OF DISPLAYING COMMUNICATION STATUS IN GLUCOSE MONITORING SYSTEM

Resumen de: EP4663120A1

One embodiment may provide a method of displaying a communication status in a glucose monitoring system, the method including displaying a communication status of a communication module in a terminal configured to transmit and receive data with a sensor transmitter, when the communication module is turned off, delaying a display of a communication module turn-off for one period of time by the terminal, and if the turn-off of the communication module persists for the one period of time, displaying the communication module turn-off.

METHOD FOR TRANSMITTING/RECEIVING BIOMETRIC INFORMATION WITHOUT LOSS IN CONTINUOUS GLUCOSE MONITORING SYSTEM

Resumen de: EP4664482A2

The present disclosure relates to a method for transmitting or receiving biometric information in a continuous glucose monitoring system and, more specifically, to a method for transmitting or receiving biometric information, in which: when a sensor transmitter generates a transmission packet, the transmission packet is generated to include a generation identifier for identifying the transmission packet or biometric information according to a generation order of the transmission packet or the biometric information, and therefore the biometric information may be transmitted or received without a loss thereof via the generation identifier; and a transmission packet or biometric information, which a communication terminal has failed to receive, is correctly determined on the basis of a packet generation identifier or a total number of transmission packets, so that only biometric information or a transmission packet, which has failed to be received between the sensor transmitter and the communication terminal, may be transmitted or received in a distinguished manner.

INTRAVASCULAR ARTIFICIAL PANCREAS

Resumen de: CN120787146A

Intravascular artificial pancreatic devices and methods of making the same are disclosed herein.

METHOD FOR IMPROVING BLOOD GLUCOSE CONTROL OF A HYBRID CONTROLLER

Resumen de: US2025375574A1

A method for improving blood glucose control of a hybrid controller meal and exercise announcement by substituting patient-initiated meal boluses of said hybrid controller by an automatic insulin correction signal without retuning of said hybrid controller, and by incorporating rescue carbohydrates suggestion for hypoglycemia mitigation, comprising the steps of measuring a plasma glucose (G(t)) signal by means of a continuous glucose monitor (CGM), calculating a glucose level (Ĝ(t)) by using a glucose-insulin model; computing a disturbance term d(t), generating a virtual signal uIMC(t), for mitigating the effect of d(t) on the output, by means of an IMC filter Q(s) and converting the virtual signal uIMC(t) into three feed forward actions: insulin infusion, rescue carbohydrate suggestion, and insulin-on-board reduction.

NON-INVASIVE BLOOD GLUCOSE MONITORING DEVICE AND SYSTEM

Resumen de: WO2025253234A1

A system and method for non-invasive blood glucose level determination and proactive management are disclosed. A sensing device comprises a capacitance-to-digital converter (CDC) sensor, featuring an active shield electrode and single-ended mode operation, to measure capacitance variations indicative of net body charge modulation by systemic physiological activity correlated with blood glucose. The device also includes at least one skin conductance sensor. A processor determines blood glucose levels from combined CDC and skin conductance data, optionally using machine learning. Further, a proactive artificial intelligence (AI) system, employing supervised and reinforcement learning models, analyzes real-time and historical data to predict blood glucose trajectories and the likelihood of future dysregulation. Crucially, the AI dynamically generates a personalized schedule of recommended actions (e.g., relating to diet, exercise, or medication timing) for managing the subject's blood glucose, providing alerts and the action plan to enhance diabetes self-management.

MEMS PLATFORM TO CREATE FLUID SEAL AND PATH BETWEEN RESERVOIR AND CANNULA OF A DEVICE FOR DELIVERING INSULIN

Resumen de: WO2025255026A1

A device for delivering medication to a user, the device configured to be mounted to the user, the device comprising: (a) a baseplate and a housing configured to engage the baseplate to form an interior therein; (b) a platform mounted to the baseplate within the interior, the platform configured to support a micropump having an inlet port for communicating with a reservoir and an outlet port for communicating with a cannula for delivering the medication to the use.

GLUCOSE SENSOR USING A COMPACT AND COST-EFFECTIVE PHOSPHORESCENCE IMAGER AND MACHINE LEARNING

Resumen de: WO2025254973A1

A computational continuous glucose monitoring system is disclosed which integrates a biocompatible phosphorescence-based insertable sensor and a custom-designed phosphorescence imager (PI). This PI captures phosphorescence lifetime images of an insertable sensor through the skin where the lifetime of the emitted phosphorescence signal is modulated by the local concentration of glucose. The lifetime images acquired through the skin are processed by neural network-based models for misalignment-tolerant inference of glucose levels, accurately revealing normal, low (hypoglycemia) and high (hyperglycemia) concentration ranges. Using a 1-mm thick skin phantom mimicking the optical properties of human skin, in vitro testing of the PI using glucose-spiked samples yielded 88.8% inference accuracy, also showing resilience to random and unknown misalignments within a lateral distance of ~4.7 mm. Lateral misalignments beyond 5 mm prompted user intervention for re-alignment.

SIMPLIFIED INSULIN DELIVERY FOR DIABETICS

Resumen de: US2025375573A1

A simplified insulin pump allows diabetics to identify routine patterns in their daily lifestyle that provide a generally accurate typical pattern of activity and meals. An infusion regimen can be programmed into the pump that generally correlates with this typical pattern to provide a viable treatment option for a diabetic without the need for specific and precise matching of insulin to carbohydrate consumption or activity level.

Minimization of Noise in Optical Dat Capture for Liquids By Light Modulation Means

Resumen de: US2025377296A1

A process and sensor system with particular control of polarization of the interrogating light beams useful for determining a concentration of a targeted molecule M (such as glucose) within a given time period in a liquid sampling matrix through use of a Direct Infrared Laser Absorption Spectroscopy Technique.

HIGHLY INTEGRATED GLUCOSE SENSOR DEVICE

Resumen de: WO2024160808A1

The present disclosure relates to highly integrated sensor devices such as implantable devices, continuous monitoring devices and portable smart devices for determining a physiological parameter in a bodily fluid and/or tissue of a subject. Further, the present disclosure relates to methods for determining a physiological parameter in a bodily fluid and/or tissue of a subject.

A DEVICE FOR NON-INVASIVE ANALYTE MEASUREMENT

Resumen de: WO2025247647A1

The invention provides an apparatus for non-invasive in vivo measurement by Raman spectroscopy of analyte presence and/or concentration, such as glucose, in the skin of a subject, the apparatus comprising; a planar probe having one or more optical sources for irradiating a sample such as the skin of a subject; a spectrometer configured to receive Raman scattered radiation collected from the sample in response to the received radiation from the one or more optical sources; a numerical aperture controller to determine the numerical aperture of the apparatus, and thereby control the input light received by the spectrometer.

METHOD OF PROVIDING NOTIFICATION OF SIGNAL LOSS IN GLUCOSE MONITORING SYSTEM

Resumen de: US2025366741A1

One embodiment may provide a method of providing a notification of signal loss in a glucose monitoring system, the method including, when a communication failure occurs between a terminal and a sensor transmitter, delaying a signal loss notification for a first period of time by the terminal, when the communication failure persists for the first period of time, further determining whether signal loss persists for a second period of time by the terminal, when the signal loss persists for the second period of time, generating the signal loss notification by the terminal, and outputting, by the terminal, the signal loss notification to a user.

INSULIN MONITORING AND DELIVERY SYSTEM AND METHOD FOR CGM BASED FAULT DETECTION AND MITIGATION VIA METABOLIC STATE TRACKING

Resumen de: US2025367366A1

An insulin monitoring system includes one or more processors, one or more computer-readable storage devices, and program instructions stored on at least one of the one or more storage devices for execution by at least one of the one or more processors. The program instructions include: first program instructions to track, in real time, the amount of insulin active in a patient; second program instructions to calculate the amount of insulin need of the patient by tracking the patient's metabolic states; third program instructions to compare the insulin active in the patient with the insulin need of the patient; and fourth program instructions to determine an insulin fault level based on the comparison.

AUTOMATIC DEVICE CONFIGURATION

Resumen de: US2025367380A1

Techniques for automatic device configuration are disclosed herein. In some embodiments, the techniques involve receiving patient data by one or more processors of a cloud-based server device. The techniques further involve obtaining, by the cloud-based server device, and based on the patient data, a value of a total daily dose of insulin for the specific patient. The techniques further involve automatically selecting, by the cloud-based server device, before the medical device has been set up to deliver insulin to the specific patient, a therapy configuration for the medical device. The techniques further involve determining, by the cloud-based server device, a set of therapy settings for the selected therapy configuration for the specific patient based upon the value of the total daily dose. The techniques further involve automatically configuring, via a non-medical device, the medical device with the set of therapy settings in a startup mode.

HYBRID BIOELECTRONIC/ENGINEERED CELL IMPLANTABLE SYSTEM FOR THERAPEUTIC AGENTS DELIVERY AND APPLICATIONS THEREOF

Resumen de: US2025367371A1

A hybrid bioelectronic implantable device containing engineered cells for delivery of therapeutic agents to a subject to treat a medical condition of the subject. The device comprises an implantable device implantable inside the subject's body, wherein the implantable device comprises at least one cell housing containing the engineered cells; and an optical stimulating system within the at least one cell housing, wherein the optical stimulating system is configured to control production of at least one type of therapeutic agents by the engineered cells; wherein the medical condition of the subject comprises one of a sleep disorder, a circadian rhythm disorder, neuro disorders, infertilities, diabetes, obesity, eating disorders, cancers, bone marrow disorders, autoimmune disorders, addictive disorders.

INSULIN PATCH PUMP

Resumen de: US2025367370A1

A user-wearable patch pump system for delivery of insulin or other medicament can include a pump and an attachment portion that attaches the pump to a user's body. The pump can include a drive unit and a disposable cartridge containing a medicament with the drive unit configured to cause the pump to deliver the medicament in the cartridge to the user. The attachment portion can include a retention frame configured to selectively retain the pump therein and an adhesive patch configured to be attached to the user's body. The pump can be selectively attached to the retention frame and used to deliver medicament either through a cannula to an infusion site directly beneath the retention frame or through tubing to an infusion site displaced from the retention frame.

IMPLANTABLE SENSOR DEVICES, SYSTEMS, AND METHODS

Resumen de: US2025366749A1

Disclosed herein are devices, systems, and methods for a continuous analyte sensor, such as a continuous glucose sensor. In certain embodiments disclosed herein, various in vivo properties of the sensor's surroundings can be measured. In some embodiments, the measured properties can be used to identify a physiological response or condition in the body. This information can then be used by a patient, doctor, or system to respond appropriately to the identified condition.

METHODS AND SYSTEMS FOR ENHANCING BLOOD GLUCOSE REGULATION AND TREATMENT OF DIABETES

Resumen de: US2025366743A1

Methods, systems, and devices for regulating blood glucose such as implantable encapsulated devices optionally with insulin and/or glucagon secreting cells in combination with glucose sensors and insulin infusion systems. For example, encapsulation devices may be connected to an insulin infusion pump for distribution of insulin. The insulin infusion pump may feature an insulin pouch fluidly connected to an insulin pump (or a syringe) and a glucose sensor separate from the encapsulation device. The system may feature an additional implantable device comprising insulin and glucagon secreting cells.

FOUR-COMPARTMENT DIFFUSION MODEL OF INSULIN IN HUMANS

Nº publicación: US2025372257A1 04/12/2025

Solicitante:

US GOV AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS [US]
United States Government As Represented By The Department of Veterans Affairs