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176
resultados
Última actualización
27/09/2024 [10:09:00]
Resumen de: US2024306650A1
The present disclosure provides methods for improving the nutrient utilization, resistance to abiotic stress, and recovery from abiotic stress of a host plant by applying a microalgae composition to the host plant. The disclosure also provides methods for improving soil fitness and improving rhizospheric activity and/or growth by applying a microalgae composition to the soil.
Resumen de: US2024309407A1
Methods and compositions for increasing lipid production in cyanobacteria where the cyanobacteria is incubated in the presence of non-lethal amounts of antibiotic. Non-lethal doses of antibiotic weakens the cell membrane facilitating migration of fatty acids from the cell, reducing inhibition feedback of fatty acid precursor enzymes, leading to an increase in fatty acid production.
Resumen de: EP4431105A1
It is an object of the present invention to provide a means capable of appropriately regulating differentiation of T cells, in order to avoid overactivation of T cells after stimulation of the T cells with superantigens or the like and the subsequent decrease in the immune functions (exhaustion of the immune system). The present invention relates to a T cell differentiation-regulating agent, comprising, as an active ingredient, an algal body of microalgae belonging to the genus Coccomyxa, a dry powder thereof, or an extract thereof.
Resumen de: EP4431593A1
The present invention relates to a novel strain of Schizochytrium sp. with easy intracellular oil extraction and a method for producing oil containing omega-3 using same. The novel microalgae of Schizochytrium sp. according to the present invention have a high fat content compared to other biomass and especially have a high content of unsaturated fatty acids such as docosahexaenoic acid and eicosapentaenoic acid, and thus allow easy extraction of biomass produced from the microalgae or by culturing and fermenting, and easy extraction of fat components including unsaturated fatty acid from the biomass. Therefore, the microalgae, and a dried biomass product and bio-oil produced therefrom may be utilized as a composition for feed or a composition for food.
Resumen de: EP4431594A1
The present application relates to a novel strain of Schizochytrium sp. with easy intracellular oil extraction and a method for producing oil containing omega3 using same. The novel microalgae of Schizochytrium sp. according to the present invention has a high content of fat in biomass, specially a high content of unsaturated fatty acids such as docosahexaenoic acid and eicosapentaenoic acid, and thus it is very easy to extract biomass produced by itself or by cultivation and fermentation and fat components including unsaturated fatty acids from the biomass. Accordingly, the microalgae, and dried biomass and bio-oil prepared therefrom can be helpfully used as a composition for feed or a composition for food.
Resumen de: US2024299880A1
The present disclosure discloses a method for capturing and removing carbon oxide using photo-cultivation, the method including a carbonic anhydrase providing step in which carbonic anhydrase is provided to culture medium as a reaction catalyst; a carbon dioxide supplying step in which a processing object gas containing carbon dioxide is supplied to the carbonic anhydrase and the culture medium; a carbon dioxide converting step in which the carbon dioxide comes into contact with the carbonic anhydrase and the culture medium to convert the carbon dioxide into inorganic carbonic acid; and a carbon oxide consuming step in which the inorganic carbonic acid is employed and consumed in photosynthesis of microalgae contained in the culture medium.
Resumen de: WO2024181448A1
The present invention addresses the problem of providing a food composition and a pharmaceutical composition which can be used as a safe and highly effective blood pressure improver that exhibits a high blood-pressure improvement effect even at low doses of ingestion. The blood pressure improver according to the present invention is characterized by: comprising any one of microalgae containing n-6 docosapentaenoic acid (n-6DPA), a fatty acid composition containing n-6DPA, or n-6DPA; and by being orally administered.
Resumen de: WO2024181756A1
A feed composition comprising microalgae-derived biomass according to the present application uses microalgae having a high content of protein, fat, and minerals and free of factors that degrade feed quality, and thus can be effectively used as a fish feed composition.
Resumen de: US2024294864A1
The invention relates to a novel method to produce small RNAs targeting virulence factors, essential genes and/or antimicrobial resistance genes of phytopathogens. More specifically, the invention involves the expression of exogenous RNA interference (RNAi) precursor(s) in Chlorella cells, which in turn express and release Extracellular Vesicle (EV)-embedded antimicrobial small RNAs. These EVs can be collected from the cell-free medium of Chlorella cultures, and further concentrated and purified for biocontrol applications. Importantly, Chlorella EVs protect small RNAs from ribonuclease-mediated digestion, indicating that these lipid-based particles not only act as natural vectors of small RNAs towards pathogenic cells, but also presumably limit their degradation in the environment. The invention can thus likely be used to reduce the pathogenicity and growth of a wide range of pathogens or, potentially, to enhance beneficial effects and growth of plant-associated symbiotic and commensal microbes. Furthermore, because the integrity of Chlorella EV-embedded antimicrobial siRNAs remains unaltered when produced in photobioreactors, and when stored frozen, this method has the potential to be further exploited for the industrialization and manufacturing of a novel generation of microalgae-based biologicals.
Resumen de: GB2627745A
A recombinant Chlamydomonas reinhardtii capable of producing bromoform comprises an expression cassette comprising a constitutive or inducible promoter operatively coupled to a nucleic acid sequence encoding a vanadate-dependent bromoperoxidase (vBPO). Also described are a method of producing the recombinant C. reinhardtii, a method for producing bromoform using the recombinant C. reinhardtii, and the resultant bromoform- containing C. reinhardtii. An animal feed composition including the bromoform-containing C. reinhardtii, and methods of reducing methane emission, inhibiting methanogenesis, increasing milk yield and/or increasing body weight gain in an animal using the bromoform-containing C. reinhardtii are also described. The vBPO may be from a marine cyanobacterium or marine alga such as Acaryochloris marina or Asparagopsis taxiforma. The promoter may be a C. reinhardtii plastome promoter such as atpA or psaA. The recombinant C. reinhardtii may comprise a positive selection marker comprising a wild type PsbH gene. The expression cassette may be present in a plasmid vector and stably integrated into the PsbH locus of the C. reinhardtii plastome. The C. reinhardtii may be a TN72 strain C. reinhardtii.
Resumen de: WO2024181756A1
A feed composition comprising microalgae-derived biomass according to the present application uses microalgae having a high content of protein, fat, and minerals and free of factors that degrade feed quality, and thus can be effectively used as a fish feed composition.
Resumen de: US2024287440A1
The invention relates to a method of making a product for human consumption which comprises partially lysed microalgae, said method comprising a) preparing a suspension of microalgae, wherein the microalgae belong to a phylaselected from Chlorophyta, Ochrophyta, and Heterokonta; b) applying a pulsed electric field to the suspension of microalgae, wherein said pulsed electric field has a specific energy input between 25 to 150 kJ per kg suspension (kg sus−1); c) optionally treating the microalgae with enzyme; d) incubating the biomass suspension at 300 rpm, 4-37° C. for 6-48 h e) forming a biomass of partially lysed microalgae; and f) adding the biomass of partially lysed microalgae to a product for human consumption.
Resumen de: US2024287441A1
Disclosed are modified strains of Chlorella microalgae species, the modified strains having a reduced chitin content. Also disclosed is a method for producing them. The method involves performing mutagenesis of a parent strain of the microalgae. Furthermore, disclosed is a composition comprising algae biomass derived from the modified strains and their use in food and/or cosmetics amongst other applications. Advantages of the low chitin content include aiding digestibility and nutrient availability of the whole-cell ingredient without further downstream processing.
Resumen de: US2024287436A1
A method and system for monitoring invasive species in an algal bioreactor utilizes a low resolution Raman spectrometer (LRRS) system and signal processing methods based upon Support Vector Machine (SVM) models. A spectrum preprocessing algorithm transforms LRRS spectra into normalized spectral data vectors. An ex-situ method is used to analyze a calibration set of known samples of a suspension containing a desired biomass, such as spirolina, together with various concentrations of invasive algal or cyanobacterial species. The ex-situ method generates SVM models and their associated SVM support vectors for classification modeling. An in-situ method uses the SVM models to provide an output vector of probability values corresponding to the presence of invasive species in an unknown sample, and optionally to provide an additional output vector of probability values corresponding to concentrations of the invasive species in the unknown sample.
Resumen de: US2024287442A1
The invention relates to the field of biotechnology. A strain of microalgae Chlorella sp. VADA 2020 was isolated from water samples of Lake Tarmakul of the Chanovsky district of the Novosibirsk region and deposited in the Collection of Microalgae of the Plant Physiology Institute, RAS, under the registration number IPPAS C-2048. Available nutrient media are used for cultivating the strain. Namely, biomass with a protein content of 48.1 wt. %, and with a content of unsaturated and monounsaturated fatty acids in an amount of 59.1 wt. % (of the total content), is produced that can be used as raw materials to produce food additives. The invention makes it possible to produce biomass with a high content of protein and unsaturated fats, suitable for use for food purposes. 2 tbl, 2 ex.
Resumen de: KR20240130420A
본 발명은 카로티노이드 고생산 미세조류 및 이를 이용한 카로티노이드 생산방법에 관한 것으로, 보다 상세하게는 수탁번호 KCTC15260BP로 기탁된 클로렐라 속 (Chlorella sp.) HS5 미세조류; 및 상기 미세조류를 암배양 하는 단계를 포함하는 카로티노이드 생산방법에 관한 것이다.
Resumen de: US2024279594A1
The present invention relates to recombinant cyanobacterial cells for the production of a chemical compound of interest. In particular, the present invention relates to genetic modifications that introduce one or more heterologous phosphopantetheinyl transferases (PPTases) into a cyanobacterial cell. These cells can, optionally, further comprise heterologous carrier protein and nucleic acid constructs that provide the cyanobacterial cells with the capability of producing chemicals of interest or compounds of interest, such secondary metabolites polyketides, nonribosomal peptides and their hybrids, the three major families of bioactive natural products, of cyanobacteria and other bacterial phyla, secondary metabolites analogs, and unnatural compounds.
Resumen de: US2024263112A1
A culture device includes an accommodation portion that accommodates a culture solution and microalgae. The accommodation portion is provided with a guide portion and a gas supply portion. The gas supply portion includes an extended tube section that extends from an upper portion to a lower portion of the guide portion in the depth direction. The extended tube portion supplies gas at the lower portion of the guide portion in the depth direction. This gas causes convection in the culture solution. The convection includes an upward flow from a lower portion to an upper portion of the accommodation portion in the depth direction. The extended tube portion is located in an upward flow region where the upward flow region is the portion through which the upward flow passes.
Resumen de: US2024263113A1
A culture system includes a culture device that includes a culture tank for culturing microalgae, and a collection device that collects a culture solution. The culture tank includes a bottom portion located at the lowest position in the depth direction. The collection device includes a collection tube housed in the culture tank. The collection tube is a tubular body having an internal space. The collection tube includes a bottom side collection portion that extends along the bottom portion of the culture tank. The bottom side collection portion includes an open port formed at a site facing upward in the depth direction of the culture tank.
Resumen de: US2024261349A1
A pharmaceutical complex for radioprotection is disclosed, as well as its preparation method and applications. Within the pharmaceutical complex, the binding between Amifostine and natural microalgae is driven by osmotic pressure. The complex is gradually degraded in the gastrointestinal tract after oral administration. The degradation of the complex makes it thoroughly cover the intestine and slowly release the drug, thereby increasing the drug concentration in the small intestine, sufficiently exerting radioprotective effects on the intestinal tissues, and avoiding systemic toxicity to the gastrointestinal tract. Additionally, the pharmaceutical complex can function as supplementary nutritional substances and regulate intestinal inflammation. The excellent oral safety, feasible preparation, simple storage, and intake of the complex prompt absorption efficiency and oral safety settle the existing issues of drug preparation technologies. The pharmaceutical complex offers wide application prospects in the field of intestinal radioprotection.
Resumen de: WO2024161109A1
The invention relates to an algae biomass having particular values within a defined colour space. The invention further relates to a strain of Chlorella microalgae having a genetic mutation in genes encoding for specific subunits of magnesium chelatase, preferably magnesium chelatase subunit, and also relates to a method of producing a strain of Chlorella microalgae having such mutations.
Resumen de: WO2024161108A1
Disclosed is a chlorophyll-deficient strain of Chlorella microalgae having a protein content of at least 50% w/w. Also disclosed is a method of producing a chlorophyll-deficient strain of Chlorella microalgae having a protein content of at least 50% w/w. Also disclosed is a composition comprising an algae biomass derived from the aforementioned chlorophyll-deficient strain of Chlorella microalgae or obtained by performing aforementioned method.
Resumen de: WO2024160738A1
The present invention relates to a food composition comprising Chlorella protein material, wherein the protein material is sourced from a chlorophyll-deficient strain of Chlorella microalgae and wherein the food composition is in the form of a meat analogue or a dry savoury snack.
Resumen de: WO2024160737A1
The present invention relates to a food composition comprising Chlorella biomass material, wherein the biomass material is sourced from a chlorophyll-deficient strain of Chlorella microalgae and wherein the Chlorella biomass material comprises at least 50 wt% of Chlorella protein by dry weight of the Chlorella biomass and wherein the food composition is in the form of a meat analogue or a dry savoury snack.
Nº publicación: EP4410984A1 07/08/2024
Solicitante:
SHANGHAI SIPENG TECH LTD [CN]
Shanghai Sipeng Technology Ltd
Resumen de: EP4410984A1
Provided are a genetically engineered strain for producing polylactic acid and a method for producing polylactic acid. The method includes: synthesizing target gene using D-lactate dehydrogenase gene, propionyl-CoA transferase gene, and polyhydroxyalkanoate synthase gene; and performing double enzymatic cleavage on a vector; purifying; and transforming competent cells to obtain a recombinant plasmid; extracting DNA of the recombinant plasmid; introducing the DNA into an engineering strain, and extracting and verifying to obtain an engineering cell strain; and then culturing the engineering cell strain under light in a culture medium, in which carbon dioxide is introduced; centrifuging; drying; and recycling. According to the present application, by modifying natural cyanobacteria and using a high density fermentation strategy, the biomass of the cyanobacteria is significantly increased. According to the present application, the problem in the related art, i.e., polylactic acid can be only produced by using sugar-derived raw material, is solved.
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