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Bioimpresión 3D

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LastUpdate Última actualización 19/10/2024 [07:14:00]
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制造用于输送药物的喷雾装置的方法

NºPublicación:  CN118750699A 11/10/2024
Solicitante: 
船井电机株式会社
CN_118750699_PA

Resumen de: US2023364625A1

A fluid jet ejection device, a method of making a fluid jet ejection head for a fluid ejection device, and a method of improving the plume characteristics of fluid ejected from the fluid jet ejection head. The fluid jet ejection device includes a cartridge body; and a fluid jet ejection cartridge disposed in the cartridge body. The fluid jet ejection cartridge contains a fluid and an ejection head attached to the fluid jet ejection cartridge. The ejection head contains a plurality of fluid ejectors thereon and a nozzle plate having a plurality of fluid ejection nozzles therein associated with the plurality of fluid ejectors, wherein a first portion of the plurality of fluid ejection nozzles have a first axial flow path length and a second portion of the plurality of fluid ejection nozzles have a second axial flow path length greater than the first axial flow path length.

CONTROL OF HEATING AND COOLING IN 3D BIOPRINTING

NºPublicación:  WO2024209179A1 10/10/2024
Solicitante: 
COPNER BIOTECH LTD [GB]
COPNER BIOTECH LTD
WO_2024209179_A1

Resumen de: WO2024209179A1

Disclosed is a 3D printing assembly (10), suitable for bioprinting, the assembly (10) including an enclosure (100) defining an enclosure internal area (101), the assembly further including a bioprinter (200) enclosed within the internal area (101), the bioprinter (200) comprising a bioprinter bed (240), the enclosure (100) comprising plural sides (110), one or more of said sides having at least one temperature regulator element (112) in the respective side (110), wherein the or each temperature regulator element (112) is arranged to introduce heat energy into, and remove heat energy from the internal area (101), and wherein the bioprinter bed (240) has at least one bed temperature regulator element (242) in or on the bioprinter bed (240) further arranged to introduce heat energy into, and remove heat energy from the bioprinter bed (240). The temperature control may be aided by air flow from a fan (131) or the like.

解剖学的構造物のレプリカを作成する方法およびシステム

NºPublicación:  JP2024537108A 10/10/2024
Solicitante: 
シュービンシニア,スティーブンエー.
JP_2024537108_PA

Resumen de: MX2024003829A

Creating a replica of an anatomical structure. In one embodiments a method includes: accepting pictures of the anatomical structure of a subject; creating an object file that contains an initial model of an outside surface of the anatomical structure; cutting the initial model to a predetermined exterior shape circumscribing the anatomical structure to create a positive model; creating a negative model from the positive model; placing a stem tool object on an outside surface of the negative model in relationship to an orifice, thereby creating a final negative model; placing a zeroing and angling object to align the negative model to a predetermined angle; placing a base tool object by coupling the base tool object to the outside surface; printing, by way of a three-dimensional printer, the final negative model to create a negative mold; and casting the replica of the anatomical structure using the negative mold.

Sistema para preparar los dientes para la colocación de carillas

NºPublicación:  ES2981769T3 10/10/2024
Solicitante: 
VIAX DENTAL TECH LLC
Viax Dental Technologies LLC
MX_2024003701_A

Resumen de: US2024335253A1

A dental overlay device for the placement of one or more veneers in a mouth of a patient comprises a curved body. The curved body further includes a body surface and a plurality of holes. The body surface is complementary to and configured for contacting portions of one or more teeth in the mouth of a patient, including distal teeth on opposite sides of the patient's mouth, to secure the curved body in a suitable position on the patient's teeth. The plurality of holes extend through the curved body and correspond to locations on a plurality of teeth.

錠剤印刷装置及び錠剤印刷方法

NºPublicación:  JP2024139932A 10/10/2024
Solicitante: 
芝浦メカトロニクス株式会社
JP_2024139932_PA

Resumen de: JP2024139932A

【課題】効率よく錠剤に印刷を行うことを可能にする。【解決手段】実施形態に係る錠剤印刷装置1は、錠剤Tを搬送する搬送装置21と、搬送装置21により搬送される錠剤Tに印刷を行うインクジェットヘッドと、搬送装置21に向けて気体を吹き付ける気体吹付装置(例えば、乾燥装置26)と、を備え、気体吹付装置は、インクジェットヘッドにより印刷が行われた錠剤Tを乾燥させるための第1の流量と、搬送装置21に付着した錠剤Tの粉を除去するための第2の流量とを切り替えて、搬送装置21に向けて気体を吹き付け、第2の流量は、第1の流量よりも大きい。【選択図】図1

3D PRINTED DIELECTRIC ELASTOMER ACTUATOR

NºPublicación:  WO2024210849A1 10/10/2024
Solicitante: 
NANYANG TECHNOLOGICAL UNIV [SG]
NANYANG TECHNOLOGICAL UNIVERSITY
WO_2024210849_PA

Resumen de: WO2024210849A1

Disclosed herein is a method of manufacturing a dielectric elastomer actuator, the method comprising: (a) providing an additive-manufactured dielectric structure formed from a dielectric elastomer that comprises a first and second plurality of channels; and (b) inserting into the first and second plurality of channels an electrically conductive material to provide the dielectric elastomer actuator, wherein the dielectric elastomer is formed from a resin that comprises an aliphatic urethane diacrylate and an epoxy aliphatic acrylate. Also disclosed herein is a dielectric elastomer actuator comprising: an additive-manufactured dielectric structure formed from a dielectric elastomer that comprises a first and second plurality of channels; and an electrically conductive material within the first and second plurality of channels, wherein the dielectric elastomer is formed from a resin that comprises an aliphatic urethane diacrylate and an epoxy aliphatic acrylate.

CANNABINOID COMPOSITIONS AND PRODUCTS

NºPublicación:  WO2024209332A1 10/10/2024
Solicitante: 
BUZZELET DEVELOPMENT AND TECH LTD [IL]
BUZZELET DEVELOPMENT AND TECHNOLOGIES LTD

Resumen de: WO2024209332A1

Provided are printable compositions comprising a cannabinoid and cannabis wax, products comprising such compositions and a substrate, methods for the production thereof and methods of use thereof in providing an accurately reproducible dose of a cannabinoid to a subject. Further provided is a product comprising a smokable substrate and at least one composition comprising at least one cannabinoid.

INVERTED CONTACT-AIDED ROLLING ELEMENT MECHANISMS AND DEVICES

NºPublicación:  WO2024211902A1 10/10/2024
Solicitante: 
33 MEDICAL INC [US]
33 MEDICAL, INC
WO_2024211902_A1

Resumen de: WO2024211902A1

Inverted contact-aided rolling element mechanisms and devices are discussed herein. In various embodiments, the contact-aided compliant mechanism includes a first rigid component, a second rigid component, a first flexible component, a second flexible component, each of the first and second flexible components comprising a first end, a second end, and a third end, and the first and second flexible components disposed between the first and second rigid components.

JOINT IMPLANTS HAVING POROUS STRUCTURES FORMED UTILIZING ADDITIVE MANUFACTURING AND RELATED SYSTEMS AND METHODS

NºPublicación:  AU2024219835A1 10/10/2024
Solicitante: 
ENCORE MEDICAL LP DBA DJO SURGICAL
Encore Medical, LP DBA DJO Surgical
AU_2024219835_A1

Resumen de: AU2024219835A1

DJOSURG.055WO JOINT IMPLANTS HAVING POROUS STRUCTURES FORMED UTILIZING ADDITIVE MANUFACTURING AND RELATED SYSTEMS AND METHODS A medical implant which comprises a porous lattice is fabricated with additive manufacturing techniques such as direct metal laser sintering. A CAD model of the porous lattice is created by defining a trimming volume and merging some lattice elements with adjacent solid substrate.

EDIBLE RECEPTACLE FOR PHARMACEUTICALS

NºPublicación:  US2024336414A1 10/10/2024
Solicitante: 
EXPRESS SCRIPTS STRATEGIC DEV INC [US]
Express Scripts Strategic Development, Inc

Resumen de: US2024336414A1

An edible receptacle for pharmaceuticals, components thereof, and associated methods. The edible pharmaceutical receptacle includes a plurality of pharmaceuticals including different first and second pharmaceuticals and an edible pharmaceutical card. The edible pharmaceutical card includes a plurality of edible dosing sections joined together. The plurality of edible dosing sections include a first edible dosing section directly joined to a second edible dosing section. The first and second edible dosing sections are arranged to be manually broken apart to separate the first and second edible dosing sections from one another. The first edible dosing section contains the first pharmaceutical of the plurality of pharmaceuticals and the second edible dosing section contains the second pharmaceutical of the plurality of pharmaceuticals.

APPARATUS AND METHOD FOR ACOUSTOPHORETIC PRINTING

NºPublicación:  US2024336064A1 10/10/2024
Solicitante: 
PRESIDENT AND FELLOWS OF HARVARD COLLEGE [US]
President and Fellows of Harvard College
US_2021154998_A1

Resumen de: US2024336064A1

A method of acoustophoretic printing comprises generating an acoustic field at a first end of an acoustic chamber fully or partially enclosed by sound-reflecting walls. The acoustic field interacts with the sound-reflecting walls and travels through the acoustic chamber. The acoustic field is enhanced in a chamber outlet at a second end of the acoustic chamber. An ink is delivered into a nozzle positioned within the acoustic chamber. The nozzle has a nozzle opening projecting into the chamber outlet. The ink travels through the nozzle and is exposed to the enhanced acoustic field at the nozzle opening, and a predetermined volume of the ink is ejected from the nozzle opening and out of the acoustic chamber.

Optimized Biomaterials of Various Cells and Tissues from Sustainable Sources

NºPublicación:  US2024335588A1 10/10/2024
Solicitante: 
NEW YORK UNIV IN ABU DHABI CORPORATION [AE]
New York University in Abu Dhabi Corporation
WO_2023118966_A1

Resumen de: US2024335588A1

The present disclosure relates to biomaterials derived from sustainable sources. Described herein are biomaterials and tissue engineering constructs comprising components derived from sustainable sources such as from tunicates, fish skin and bananas.

ORAL DEVICES

NºPublicación:  US2024335317A1 10/10/2024
Solicitante: 
SLOW WAVE INC [US]
SLOW WAVE, INC
US_11813192_PA

Resumen de: US2024335317A1

Oral devices for reducing obstructive sleep apnea, snoring and/or nasal drainage, or improving sleep even without substantial reduction in snoring. One device includes an upper member fitting portions of the interior and exterior surfaces of a user's upper dentition, and a lower member fitting similarly adjacent a user's lower dentition. The upper and lower members include molar and pre-molar extensions so that when a user bites or clenches, the upper right and lower right extensions impinge on one another in substantially overlapping fashion, as do the upper left and lower left extensions. In certain embodiments, patterned surfaces on mating right and left molar and pre-molar extensions reduce friction. The lower and upper molar and pre-molar extensions may have curved or arcuate shaped interior surfaces to provide more room for a user's tongue. Right and left sub-chambers formed in the upper and lower molar and pre-molar extensions may provide lateral space for the tongue. The oral devices may be produced by additive or subtractive manufacturing methods.

System For Preparing Teeth For The Placement Of Veneers

NºPublicación:  US2024335253A1 10/10/2024
Solicitante: 
VIAX DENTAL TECH LLC [US]
Viax Dental Technologies LLC
MX_2024003701_A

Resumen de: US2024335253A1

A dental overlay device for the placement of one or more veneers in a mouth of a patient comprises a curved body. The curved body further includes a body surface and a plurality of holes. The body surface is complementary to and configured for contacting portions of one or more teeth in the mouth of a patient, including distal teeth on opposite sides of the patient's mouth, to secure the curved body in a suitable position on the patient's teeth. The plurality of holes extend through the curved body and correspond to locations on a plurality of teeth.

PHOTO-ENZYMATIC PRINTING

NºPublicación:  EP4440634A1 09/10/2024
Solicitante: 
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIV [US]
The Board of Trustees of the Leland Stanford Junior University
WO_2023102558_A1

Resumen de: WO2023102558A1

Methods of making fibrin mesh are described.

PROPOSING DENTAL RESTORATION MATERIAL PARAMETERS

NºPublicación:  EP4440493A1 09/10/2024
Solicitante: 
DENTSPLY SIRONA INC [US]
DENTSPLY SIRONA Inc
US_2023165666_PA

Resumen de: US2023165666A1

A parameter recommendation module is used to propose a recommendation for dental restoration material parameters. The recommendation takes into consideration final tooth color influencing factors such as underlying tooth stump color and color of restoration fastening material such that at least one output restoration characteristic value needed to achieve a final user-specific tooth color for at least one tooth layer of the restoration is proposed.

MEDICAL DEVICE FOR TARGETED APPLICATION OF A THERAPEUTIC AGENT TO THE ROUND WINDOW OF THE COCHLEA

NºPublicación:  EP4440669A1 09/10/2024
Solicitante: 
UNIV DE BORDEAUX [FR]
INSTITUT NATIONAL DE LA SANTE ET DE LA RECH MEDICALE INSERM [FR]
CENTRE HOSPITALIER UNIV DE BORDEAUX [FR]
INST PASTEUR [FR]
UNIVERSITE DE BORDEAUX,
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM,
Centre Hospitalier Universitaire de Bordeaux,
Institut Pasteur
CN_118401274_PA

Resumen de: CN118401274A

The invention relates to a medical device (1) for delivering a therapeutic agent by bioprinting, the medical device (1) comprising a shaft body (2), the shaft body (2) comprising:-a bioprinting cartridge (4) arranged near a distal end of the shaft body (2), the bioprinting cartridge (4) comprising:-a top layer comprising a solution containing a therapeutic agent; and-an absorbing compound capable of converting light energy from the laser radiation into thermal energy and arranged to cause heating of said solution comprising a therapeutic agent to cause ejection of said solution; -an optical fiber (3) extending longitudinally in the interior cavity of the rod body (2) to deliver a laser flow onto the absorbing compound.

METHODS FOR 3D PRINTING OF POLY-4-HYDROXYBUTYRATE

NºPublicación:  EP4442767A2 09/10/2024
Solicitante: 
TEPHA INC [US]
Tepha, Inc
EP_4442767_A2

Resumen de: EP4442767A2

Methods to fabricate objects by 3D printing of poly-4-hydroxybutyrate (P4HB) and copolymers thereof have been developed. In one method, these objects are produced by continuous fused filament fabrication using an apparatus and conditions that overcome the problems of poor feeding of the filament resulting from the low softening temperature of the filament and heat creep along the fed filament. Methods using an apparatus including a heat sink, a melt tube, a heating block and nozzle, and a transition zone between the heat sink and heating block, with the melt tube extending through the heat sink, transition zone, and heat block to the nozzle are disclosed. 3D objects are also printed by fused pellet deposition (FPD), melt extrusion deposition (MED), selective laser melting (SLM), printing of slurries and solutions using a coagulation bath, and printing using a binding solution and polymer granules.

3D PRINTING COMPOSITION

NºPublicación:  EP4442722A1 09/10/2024
Solicitante: 
GC CORP [JP]
GC Corporation

Resumen de: EP4442722A1

A three-dimensional printing composition includes: a first (meth)acrylate having a urethane bond; a second (meth)acrylate having a polyconjugated diene structure and a urethane bond; and a monofunctional third (meth)acrylate having a glass transition temperature Tg of 70°C or more.

STENT, METHOD FOR MANUFACTURING STENT, AND METHOD FOR SECURING AIR FLOW BY RELIEVING STENOSIS OF RESPIRATORY ORGAN

NºPublicación:  EP4440507A1 09/10/2024
Solicitante: 
TORAY IND INC [JP]
REGENTS OF THE UNIV OF MINNESOTA [US]
Toray Industries, Inc,
Regents of the University of Minnesota
CN_118354741_PA

Resumen de: CN118354741A

The stent for the respiratory organ includes a bioabsorbable polyester copolymer. The bioabsorbable polyester copolymer is a polyester copolymer having residues of two ester bond-forming monomers, referred to as monomer A and monomer B, respectively, as main constituent units, and the R value given by the following formula is 0.25-0.99 (inclusive): R = AB/(2 A B) * 100. In the formula, A is the mole fraction (%) of monomer A residues in the polyester copolymer; B is the molar fraction (%) of monomer B residues in the polyester copolymer; AB is the molar fraction (%) of the structure (A-B and B-A) in which the monomer A residue and the monomer B residue are adjacent to each other in the polyester copolymer.

NOVEL POLYMER

NºPublicación:  EP4440699A1 09/10/2024
Solicitante: 
ST VINCENTS HOSPITAL MELBOURNE LTD [AU]
UNIV OF WOLLONGONG [AU]
SWINBURNE UNIV OF TECHNOLOGY [AU]
THE UNIV OF MELBOURNE [AU]
ST. VINCENT'S HOSPITAL (MELBOURNE) LIMITED,
University of Wollongong,
Swinburne University of Technology,
The University of Melbourne
AU_2022401058_A1

Resumen de: AU2022401058A1

A functionalised polymer comprising a polymer partially functionalised with: a plurality of photocrosslinkable moieties linked to the polymer, each photocrosslinkable moiety comprising a reactive functionality capable of photocrosslinking; and a plurality of cell adhesion moieties each linked to the polymer via a linker, each cell adhesion moiety comprising a cell adhesion motif, and wherein the functionalised polymer further comprises a plurality of functional groups capable of ionic crosslinking with an ionic crosslinking agent. A method for forming a liquified polymer composition comprising cells from a tissue sample, the method comprising: providing a tissue sample comprising cells; contacting the sample with the functionalised polymer in binding conditions, said binding conditions being conditions that enable binding of cells in the sample to the functionalised polymer, so that said cells are bound to the functionalised polymer; culturing the cells bound to the polymer under conditions and for a time that allows the cell number to increase; providing conditions to induce a solid to liquid phase change of the functionalised polymer; thereby forming a liquified polymer composition comprising cells from a tissue sample.

"3D-PRINTABLE BIOCOMPOSITES"

NºPublicación:  EP4440841A1 09/10/2024
Solicitante: 
NEWSOUTH INNOVATIONS PTY LTD [AU]
Newsouth Innovations Pty Limited
CN_118488893_A

Resumen de: AU2022399278A1

Disclosed herein are biocomposites which may be formed from compositions comprising: at least one monomer suitable for photopolymerisation; a photoinitiator; and a filler composition comprising at least one inorganic compound. The biocomposites may be formed in a process comprising 3D printing. Also disclosed herein are potential applications of the compositions and biocomposites, including in the optional treatment of bone defects or the repair of a portion of bone in a subject.

PERSONAL CARE DEVICE WITH AUDIBLE FEEDBACK

NºPublicación:  EP4440378A1 09/10/2024
Solicitante: 
THE PROCTER & GAMBLE COMPANY [US]
The Procter & Gamble Company
US_2024315425_PA

Resumen de: US2024315425A1

The present application relates generally to a personal care device for modifying a keratinous surface having one or more sensors, a treatment element adapted to deposit a personal care composition, a feedback element, and a processor. The personal care device may analyze the keratinous surface, identify keratinous imperfections, and then modify the keratinous imperfections by depositing the personal care composition. More particularly, the personal care device provides feedback on how to use the device in its best possible manner to achieve both an optimal usage experience and an optimal modification.

Cryptographically secured dental treatment planning

NºPublicación:  US12109091B1 08/10/2024
Solicitante: 
ALIGN TECH INC [US]
Align Technology, Inc
US_12109091_PA

Resumen de: US12109091B1

A method of cryptographically secured digital dental treatment planning comprises: receiving, at an intraoral scanning system, an intraoral scan of a patient's dentition, wherein the intraoral scan comprises a three-dimensional (3D) surface representing the patient's dentition at a first arrangement; encrypting, at the intraoral scanning system, the intraoral scan to create a cryptographically secured dental record of the patient's dentition; decrypting, at a treatment planning system, the cryptographically secured dental record; determining a target arrangement for the patient's dentition; determining a digital treatment plan for the patient's dentition, wherein the digital treatment plan comprises a series of intermediate arrangements for a series of aligners to move the patient's dentition from the first arrangement toward the target arrangement; adding the digital treatment plan to the cryptographically secured dental record of the patient's dentition; and sending the cryptographically secured dental record of the patient's dentition to one or more data stores.

一种用于肺活量检测的光纤封装模具、测试装置及其检测方法

Nº publicación: CN118743546A 08/10/2024

Solicitante:

诺丁汉大学卓越灯塔计划(宁波)创新研究院宁波诺丁汉大学

CN_118743546_PA

Resumen de: CN118743546A

一种用于肺活量检测的光纤封装模具、测试装置及其检测方法,该模具的结构包括相互配合的第一模具和第二模具,第一模具具有环形内凹槽,环形内凹槽中设置有相对设置的第一凸起和第二凸起,第一凸起和第二凸起之间具有间距;第二模具为中空的筒状,第二模具套设于第一模具内,且第二模具中空的内壁与第一凸起和第二凸起的外壁相适配;第二模具沿轴向设置有缺口,缺口的宽度与第一凸起和第二凸起之间的间距相等、且第一模具和第二模具套合后所述的缺口宽度方向与第一凸起和第二凸起之间的间距相对正;第一模具径向对称设置有弧形凹槽,弧形凹槽与第二模具的缺口径向相对应。本申请的方案具有能够有效避免光纤损伤或者断裂的用于肺活量检测的优点。

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