Resumen de: US20260272454A1
An apparatus includes a first stapling assembly, a plurality of staples a plurality of staple drivers, and a second stapling assembly portion. The first stapling assembly portion has a deck surface defining a plurality of apertures. The staple drivers can drive the plurality of staples through the staple apertures of the deck surface. The second stapling assembly can couple with the first stapling assembly portion. The second stapling assembly portion has a section that overlies the deck surface. At least one of the first or second stapling assembly portions include a first support feature that inhibits deflection of the deck surface during stapling.
Resumen de: EP4249257A1
A curable composition containing a radical-polymerizable monomer and a hard solid component having a volume average particle diameter of 10 nm or greater and 1,000 nm or less is provided. The content of the hard solid component is 3% by volume or greater and 40% by volume or less. The difference (n1-n2) between the refractive index (n1) of a cured product of any other component than the hard solid component and the refractive index (n2) of the hard solid component is 0.04 or greater.
Resumen de: US20260272346A1
0000 A method for measuring oxygen saturation includes determining a difference in voltage value for a light emitting diode based on a first voltage at the light emitting diode for a first current and a second voltage at the light emitting diode for a second current and determining a temperature for the light emitting diode based on the difference in voltage value. The method further includes determining an intensity of a received photonic signal corresponding to an output photonic signal output using the light emitting diode and determining an oxygen saturation level based on the intensity of the received photonic signal and the temperature for the light emitting diode. The method further includes outputting an indication of the oxygen saturation level.
Resumen de: US20260273187A1
Drug delivery system, injection device, transfer apparatus, vial holder and method of administering and transferring are disclosed which provide for passive warming of chilled injectable transferred through the transfer apparatus and into the injection device. The injection device may include a skin-facing surface including a skin boundary displacement extension or structure around a needle injection site to create a high pressure zone in the tissue. Radio frequency tracking and monitoring features for tracking patient compliance also may be provided.
Resumen de: US20260272364A1
The present disclosure describes a method for neuromodulating a subject, comprising providing (i) a cognitively engaging content, and (ii) a gamma oscillation inducing waveform, wherein said gamma oscillation inducing waveform: comprises an intensity that renders said gamma oscillation inducing waveform imperceptible to said subject; and causes a therapeutic improvement in a cognitive function, thereby neuromodulating said subject.
Resumen de: AU2026223274A1
A portable medical device for adjusting a cardiopulmonary resuscitation (CPR) treatment includes a processor. The processor is configured to determine a particular CPR treatment protocol from one or more CPR treatment protocols. The particular CPR treatment protocol may include a ratio of a number of chest compressions to ventilations for administering during a CPR cycle. The processor is configured to receive a CPR time period for the CPR treatment for the CPR treatment, to determine a number of CPR cycles for the CPR treatment based on the particular CPR treatment protocol, and to calculate a time duration of the CPR treatment based on the number of CPR cycles of the particular CPR treatment protocol. The processor is configured to compare the time duration to the CPR time period and to modify the particular CPR treatment protocol or CPR time period based on the comparison. ug u g
Resumen de: US20260278974A1
An imaging method and means for cognitive brain science based on metaverse mixed reality technology are provided, which can provide a clear, intuitive, and highly interactive brain function teaching platform, enhancing the efficiency and immersion of medical education, neuroscience research, and clinical training. The method includes the following steps: (1) modeling brain tissue based on MRI images; (2) virtual modeling fiber bundles; (3) optimizing the model; (4) converting and generating a model.
Resumen de: US20260279560A1
0000 An electrosurgical system including an electrosurgical instrument and generator to which the electrosurgical instrument is connected. The electrosurgical generator has a processor, one generator data memory and optical and our acoustic signaling and/or display providing optical and/or acoustic notifications to a user during the operation of the electrosurgical generator. The electrosurgical instrument has one instrument data memory in which a data set with structured data is stored, wherein some of this data represent signaling instructions, based on which the processor can control the output of optical and/or acoustic notifications for a user during the operation of the electrosurgical generator. The generator data memory contains an operating program for controlling the operation of the electrosurgical generator in conjunction with the electrosurgical instrument and the processor is configured to control during the operation of the electrosurgical generator the signals or notifications to be output by the signaling and/or display on the data signaling instructions stored in the instrument data memory of the electrosurgical instrument.
Resumen de: US20260275148A1
This disclosure provides polymeric materials comprising weak crosslinking covalent bonds and/or weak crosslinking units comprising a weak covalent bond. Weak covalent bonds can be used in place of hydrogen bonds present in traditional polymeric materials (e.g., polyurethanes). Advantageously, the toughness can be controlled by varying the strength of weak covalent bonds and/or by varying the number of weak covalent crosslinks. Crosslinked materials applying the weak covalent crosslinking bonds can be used to create tough materials able to resist stress relaxation. Further, the present disclosure provides polymer chains and polymeric materials comprising inchain loops (also referred to herein as rings). The inchain loops comprise weak bonds and/or weak bridges comprising at least one weak bond. This disclosure also provides compositions comprising the polymer chains, materials comprising the polymer chains, monomer units that can react to form inchain loop-comprising polymer chains, resins comprising the monomer units, and related materials, appliances, and uses.
Resumen de: US20260278782A1
An information processing device includes, at least one memory storing instructions, and at least one processor configured to execute the instructions to, acquire one or a plurality of endoscopic images, detect a polyp candidate from the endoscopic image, calculate a first type score indicating a polyp likelihood regarding the polyp candidate, store an image of the polyp candidate and the first type score in a storage unit, determine whether the polyp candidate is identical to one or a plurality of other polyp candidates stored in the storage unit; and calculate a first type integrated score by integrating the first type score and a first type score related to one or a plurality of the other polyp candidates stored in the storage unit when the candidates are determined identical to each other.
Resumen de: US20260272373A1
0000 Methods, systems, and devices for fertility prediction are described. A system may be configured to receive physiological data collected over a plurality of days, where the physiological data includes at least temperature data. Additionally, the system may be configured to determine a time series of temperature values taken over the plurality of days where the time series includes a plurality of menstrual cycles. The system may then determine a plurality of menstrual cycle length parameters associated with the menstrual cycles and determine a user fertility prediction based on the menstrual cycle length parameters. The system may generate a message for display on a graphical user interface that indicates the determined user fertility prediction.
Resumen de: US20260278792A1
A medical image processing device, an operation method and an operation program thereof are provided. The medical image processing device includes a processor configured to acquire a medical image, derive indirect finding information related to an indirect finding that represents at least one feature of a shape or a property of peripheral tissue of a lesion associated with an occurrence of the lesion by analyzing the medical image using a first machine learning model, derive provisional lesion presence probability information that indicates a provisional presence probability of the lesion, which represents at least one feature of a shape or a property of the lesion, by analyzing the medical image using a second machine learning model, and derive lesion presence probability information that indicates a presence probability of the lesion based on the indirect finding information and the provisional lesion presence probability information using a third machine learning model.
Resumen de: US20260279508A1
The present invention provides a new integrated platform that allows the validation of production processes, the standardization and the evaluation of complex natural products, allowing the characterization of the complex mixture contained within products with a therapeutic and/or healthy effect based on or consisting of from natural substances “as an entire system”, without limiting their characterization to a reductionistic chemical approach aimed at a single marker, but rather integrating qualitative-quantitative data and fingerprint characterization metabolomics of the mixture with physical and biophysical activity data thus providing a characterization of the product which is the basis of the validation process of the production process which allows to guarantee reproducibility between different batches of this product in terms of efficacy and safety. The analytical platform described here allows us to guarantee the complex natural product as a whole, taking into consideration all its quality and efficacy properties in order to guarantee the reproducibility of the effect and safety through a multidimensional analytical approach.
Resumen de: US20260275290A1
0000 The invention provides a method for producing a three dimensional thymic like structure, the method comprising: a) providing pluripotent cells from a recipient with a nucleic acid molecule comprising a FOXN1 sequence, and b) inducing said pluripotent cell to differentiate into thymic epithelium in a scaffold suitable for transplantation, as well as related methods, compositions or uses.
Resumen de: US20260274931A1
0000 Disclosed herein are methods of conducting clinical trials in Alzheimer's disease (AD). Methods of selecting a medicament and treating an AD subject are disclosed. Methods, systems, kits, and devices for selecting a subject in AD clinical trials and treatment protocols are disclosed herein.
Resumen de: US20260273132A1
This invention relates to an implant (10), including a support arrangement (12) manufactured from a form of a porous material, for receiving and supporting stem cells (14) in a supported condition, for receiving a medium in the form of a neural basal and neural induction medium mixture (20) and the support arrangement (12) being shaped and sized to conform to and be received complementally by an implant zone (16). The implant zone (16) being a space defined by an excised portion of a subject's spinal cord (18). The neural basal and neural induction medium mixture (20) provides nutrients for the development of the stem cells (14) and the growth factors, in form of neurotrophin 3, neurotrophin 4 and brain-derived neurotrophic factor (BDNF) encourage and control development of the stem cells (14), the growth factors typically being constituents of the medium mixture (20).
Resumen de: JP2022013898A
To provide a technique which enables an objective evaluation about an operative method used for actual hard tissues.SOLUTION: An information processor (1) has a processor (11). The processor (11) executes derivation processing (M12) of deriving output information including an estimation image (PI) showing a hard tissue after an operative method is applied as an evaluation basis from input information including a taken image (IM1) showing the hard tissue before the operative method is applied, by using a learned model (LM1) constructed from a machine learning.SELECTED DRAWING: Figure 5
Resumen de: US20260272557A1
Systems and methods for designing and implementing patient-specific surgical procedures and/or medical devices are disclosed. In some embodiments, a method includes receiving a patient data set of a patient. The patient data set is compared to a plurality of reference patient data sets, wherein each of the plurality of reference patient data sets is associated with a corresponding reference patient. A subset of the plurality of reference patient data sets is selected based, at least partly, on similarity to the patient data set and treatment outcome of the corresponding reference patient. Based on the selected subset, at least one surgical procedure or medical device design for treating the patient is generated.
Resumen de: US20260272788A1
The present invention relates to a mixture, for 3D printing, particularly a resin for 3D printing comprising—a monomer, oligomer or polymer, or a mixture thereof, comprising at least one acrylate or methacrylate subunit, and—a lactam, characterized in that the lactam concentration is 0.001 to 0.3 wt %, particularly the lactam concentration is 0.001 to 0.15 wt %, more particularly the lactam concentration is 0.01 to 0.1 wt %. Furthermore, the present invention relates to a polymer, in particular a dental polymer or an otoplastic polymer comprising polymerised monomers and/or oligomers or polymers and a lactam, as well as a medical product comprising said polymer.
Resumen de: US20260273859A1
Apparatus for producing three-dimensional screen-printed workpieces, in particular a 3D screen-printing machine, having a printing device for the layerwise production of at least one screen-printed workpiece in a plurality of printing operations and having a transport device for the automated transport of at least one screen-printed workpiece and/or of a workpiece carrier towards and/or away from the printing device, wherein the transport device has a carrying section for the at least form-fitting reception of a workpiece carrier.
Resumen de: US20260272305A1
0000 A system for analyzing a reflected signal during a laser procedure can include a surgical scope. A first light source emitter can be configurable to emit a first signal having a first (e.g., a non-visible) spectrum. A second light source emitter can be configurable to emit a second signal having a second spectrum (e.g., a visible or infrared (IR) spectrum). Each of the first or the second light source emitters can be coupled to or included within the surgical scope. The system can include an optical sensor configurable to detect and analyze a third signal returned from the surface of an object in response to the emitted second signal. The returned third signal can be analyzed to determine whether a reflected absolute or relative intensity or an absolute or relative spectral signature meets at least one criterion, thereby triggering at least one of: warning a user or adjusting the first signal.
Resumen de: US20260272637A1
A bio-compatible implant that is adapted for use in repairing soft tissue damage includes a fibrous scaffold having a length, a width and a thickness. The fibrous scaffold includes a plurality of fibers oriented in three orthogonal directions. In some instances, the three orthogonal directions align with the length, width and thickness of the fibrous scaffold. In some cases, two of the three orthogonal directions may be offset with respect to the length and width of the fibrous scaffold.
Resumen de: US20260277188A1
The invention relates to a system (1) for forming a deep-drawn object, wherein the system (1) comprises: —a generative manufacturing device (2) configured to generate a three-dimensional (3D) object on a build platform (3) and—a deep-drawing device (4), characterized in that the deep-drawing device (4) comprises a receiving structure (41) configured to receive the build platform (3), particularly the build platform (3) with the 3D object (5) on the build platform (3), such that when the build platform (3) is received by the receiving structure (41), the deep-drawn object can be generated by the deep-drawing device (4) based on the 3D object (5). The invention also relates to a deep-drawing device (4) and a method for forming a deep-drawn object.
Resumen de: US20260275299A1
The present invention relates a bioprinted three-dimensional tumor model which is able to reproduce the cellular heterogeneity, the spatial architecture, and the tissue-specific ECM of the tumor microenvironment. In addition, the invention refers to a process for preparing such three-dimensional tumor model, to methods for testing anticancer drugs as well as to the use of the tumor model in developing personalized medicine and developing new therapies based on the understanding of the in vitro tumor progression.
Nº publicación: US20260273185A1 17/09/2026
Solicitante:
INSULET CORP [US]
INSULET CORPORATION
Resumen de: US20260273185A1
0000 The provided examples of systems, devices and techniques improve systems and methods for keeping users of automatic drug delivery systems engaged and assisting with the optimal use of the drug delivery system. The automatic drug delivery system may include a drug delivery device and a controller. Through the use of an attrition prevention engine in a cloud-based services system that cooperates with an attrition prevention application executing on the controller of the drug delivery device, notifications that include instructions for adjusting operation of the drug delivery device as well as offer assistance to the patient to optimize performance of the drug delivery system for the patient may be provided. Optimizing the performance of the drug delivery system has been shown to prevent attrition of patients from using the drug delivery system.