Se desexas distinguir vos teus produtos, servizos ou ambos os dous doutra empresa, é posible que necesites unha marca ou nome comercial. Descobre que son, en que consiste ou seu procedemento de rexistro e que implica.
Información sobre los plazos de presentación de solicitudes de transformación de marcas de la Unión Europea en marca nacional española. Más información
Se tes un novo dispositivo, produto ou procedemento que resolva un problema técnico ou teña unha vantaxe práctica, existen distintas formas de protexelo en España e noutros países. Descobre como facelo.
A túa innovación reside na estética, a ornamentación ou a aparencia do teu produto? Protéxea mediante un deseño industrial. Descobre que dereitos confire ou rexistro e como realizar a tramitación.
As indicacións xeográficas protexen o nome dun produto orixinario dunha zona xeográfica, á cal lle debe unha determinada calidade, reputación ou outra característica. Descobre que son, en que consiste o seu procedemento de rexistro e que beneficios conceden.
As patentes publicadas en todo ou mundo son unha valiosa fonte de información científica, técnica e comercial.
El Bono 3 del Fondo para PYMEs 2025, que cubre la elaboración de Informes Tecnológicos de Patentes (ITP) y Búsquedas Retrospectivas se cerrará el lunes 10 de febrero de 2025 al cierre de la jornada laboral. Próximamente se informará sobre su reapertura. Puede consultar más información aquí.
Ése emprendedor/a ou unha empresa e queres potenciar e mellorar a rendibilidade do teu negocio protexendo de forma adecuada vos activos intangibles dá túa organización, neste espazo atoparás ou necesario.
95
resultados
Última actualización
26/02/2026 [07:06:00]
Resultados 50 a 75 de 95
Resumen de: US2025377362A1
The invention provides analytical methods for identifying and quantifying complex glycoconjugate compositions, in particular for the analysis of a glycoconjugate in a sample comprising at least 4 glycoconjugates.
Resumen de: US20260048111A1
The present disclosure relates to the technical field of medicine, and in particular to a pharmaceutical composition, preparation method and use thereof. The pharmaceutical composition includes a first active ingredient, a second active ingredient, and a pharmaceutically acceptable carrier or excipient. The first active ingredient is a microbial agent, including one or more of Staphylococcus aureus, Bordetella pertussis, diphtheria toxoid, tetanus toxoid, Salmonella typhi, and Salmonella paratyphi. The second active ingredient includes polyinosinic acid, polycytidylic acid, and vitamin. The pharmaceutical composition of the present disclosure pertains to an artificial active immunotherapy for tumors. It can “stimulate” the entire immune system, making the therapy of using bacteria to activate the human immune system to kill cancer cells highly stable and reliable. This composition can significantly save and prolong the lives of cancer patients while exhibiting extremely high safety, minimal toxic side effects, and low production costs.
Resumen de: WO2025246011A1
Provided are a method for enhancing the immunogenicity of a recombinant protein antigen and use thereof. The method comprises conjugating a polysaccharide with a recombinant protein antigen to form a nano-scale protein antigen. The polysaccharide is selected from sodium hyaluronate, chitosan, glucan, fucoidan, and sodium alginate. The recombinant protein antigen is a protein antigen derived from a bacterium. The bacterium belongs to the genus of Staphylococcus, Neisseria, Klebsiella, Escherichia, Clostridium, Salmonella, Shigella, Pseudomonas, Acinetobacter, Bordetella, Enterococcus, Haemophilus, Mycobacterium, or Streptococcus. The method not only improves the immunogenicity of the recombinant protein antigen, but also overcomes the defects of competitive immunoregulation and poor immune enhancement effects caused by bacterial capsular polysaccharide modification. The method also has the advantages of high clinical application value, simple starting material acquisition, low cost, good process stability, ease in scale expansion, high safety, and the like.
Resumen de: WO2024156739A1
The invention relates to a method for identifying a multi-parameter phenotype of microbiota. The method comprises (i) providing a sample comprising microbiota, (ii) labeling said microbiota with multiple labels, each of which binds a phenotypic parameter of said microbiota, (iii) detecting an intensity of the labelled phenotypic parameters of single cells of the microbiota by flow cytometry, and (iv) segmenting the single cells into bins based on the intensities of detected phenotypic parameters, wherein the distribution of single cells in bins represents a multi-parameter phenotype of said microbiota. The invention further relates to a system for identifying a multi-parameter phenotype of intestinal microbiota, a kit for identifying a multi-parameter phenotype of intestinal microbiota and methods for diagnosing a medical condition associated with microbiota, for example an inflammatory condition, such as an inflammatory bowel disease, in a subject.
Resumen de: CN121049237A
本发明公开一种冰箱沉降菌检测方法及检测装置，涉及检测技术领域，技术方案为，先采用Aptamer和Toehold switch策略构建检测载体作为检测介质；再将其置于待检测空间，形成固定形状和面积的检测区域并与空气接触；接着对检测区域进行图像采集，识别颜色变化区域；最后分析图像获取沉降菌检测结果。此方法无需复杂培养分离，简化流程、缩短检测时间；通过图像采集与颜色分析直观快速出结果，操作便捷。相比传统方法，它克服了费时费力、需多法结合的弊端，能快速准确检测医用冰箱沉降菌，预防交叉感染，保障药品、血液安全，具有高特异性、灵敏度，应用潜力大。
Resumen de: CN121015731A
The invention discloses an extraction method and application of guava functional components for preventing and treating piglet diarrhea. The extraction method comprises the following steps: performing vacuum drying on guava leaves at 45-60 DEG C, and crushing; mixing with an ethanol-water mixed solvent, and carrying out ultrasonic-assisted extraction; filtering the extracting solution, concentrating under reduced pressure, and freeze-drying to obtain the guava leaf extract; according to the scheme, comprehensive prevention and control of bacterial diarrhea are achieved, phenolic compounds in GE directly inhibit growth of ETEC and salmonella, compound enzymes make up the defect that piglet digestive enzymes are insufficient to reduce intestinal burden, and traditional Chinese medicine compounds enhance the intestinal convergence function; the natural plant extract, the traditional Chinese medicine compound and the food-grade enzyme preparation are taken as core components, so that the problems of drug resistance and residue of antibiotics are avoided; ultrasonic-assisted ethanol-water mixed solvent extraction is adopted, and a freeze drying technology is combined, so that the yield of phenolic compounds in GE is increased, the impurity content is reduced, and the raw material cost and the feed palatability influence are reduced.
Resumen de: CN121015906A
The invention relates to the technical field of nano-drug carriers, in particular to a preparation method and application of enzyme-responsive nano-vesicles with pillararene as a carrier, a compound 30 is used as a starting raw material and condensed with a compound 31 under the action of EEDQ to obtain a compound 32, the compound 32 is subjected to Fmoc protection removal through piperidine and diethyl ether precipitation to obtain a compound 33, and the compound 33 is subjected to enzyme-responsive reaction to obtain the enzyme-responsive nano-vesicles with pillararene as the carrier. A compound 33 and a compound 34 react in DMF to obtain a compound 35, the compound 35 is subjected to trifluoroacetic acid deprotection to obtain a compound 36, the compound 36 and a compound 37 react and are subjected to column chromatography separation to obtain a compound 38, the compound 38 and terminal alkyne pillar arene 11 are subjected to 1, 3-dipole addition under the catalysis of Cu I/TBTA to obtain a compound 39, acetyl protecting groups are removed through sodium methoxide to obtain MP5, MP5 is dissolved in deionized water containing 1% of DMSO, dialysis is performed after ultrasonic treatment, and the compound 38 is obtained. The MP5 nano vesicle solves the problem that common antibiotics cannot play a role in intracellular parasitic salmonella, so that infection is difficult to radically treat.
Resumen de: CN121022764A
The invention relates to the technical field of biology, in particular to a bacteriophage vBSalPSE29, a bacteriophage vBSalPSE29 preparation and application of the bacteriophage vBSalPSE29 preparation. The invention provides a bacteriophage vBSalPSE29, and the preservation number of the bacteriophage vBSalPSE29 is CGMCC (China General Microbiological Culture Collection Center) No.46499. The bacteriophage vBSalPSE29 is According to the salmonella pullorum bacteriophage provided by the invention, through whole genome sequencing analysis, gene sequences related to lysogenic transformation, antibiotic resistance and virulence factors are not detected in the genome of the salmonella pullorum bacteriophage, so that the biological safety of the bacteriophage for drug development and sterilization product development is ensured from the molecular level, and potential biological risks are effectively avoided.
Resumen de: CN121015753A
The invention discloses a dark plum antidiarrheal compound preparation for treating chicken diarrhea and a preparation method thereof. The dark plum antidiarrheal compound preparation is prepared from the following active ingredients: dark plum, schisandra chinensis, radix isatidis and berberis poiretii schneid in a mass ratio of (8-12): (12-16): (12-16): (8-12). The fructus mume antidiarrheal compound preparation for treating chicken diarrhea is low in price, and the cost of the fructus mume antidiarrheal compound preparation is reduced by 50% or above compared with that of currently common Chinese pulsatilla root oral liquid, Chinese pulsatilla root powder, Sihuang antidiarrheal granules, Siwei herba andrographitis powder and other compounds, and even is reduced by 500% or above compared with that of the Chinese pulsatilla root oral liquid/powder. The traditional Chinese medicine composition can completely inhibit characteristic pathological changes of peritonitis, pericarditis, perihepatic inflammation and enteritis caused by pathogenic bacteria of escherichia coli and salmonella by 100%, the cure rate of bacterial diarrhea is 100%, disordered intestinal flora and damaged intestinal villi of infected chickens can be recovered, and the inflammatory response of the infected chickens is remarkably reduced.
Nº publicación: CN121023055A 28/11/2025
Solicitante:
SOUTHWEST UNIV
\u897F\u5357\u5927\u5B66
Resumen de: CN121023055A
The invention discloses an avian salmonella nucleic acid rapid detection method based on a RAA-CRISPR-Cas13a technology and a kit, and belongs to the technical field of biochemistry and molecular biology. On the basis of the designed RAA primer pair and crRNA, the avian salmonella nucleic acid detection based on an RAA-CRISPR-Cas13a enzyme molecular system is established, the system is high in specificity and sensitivity, rapid detection of avian salmonella can be achieved within 30 minutes, the detection sensitivity of a fluorescence method can reach 100 copies/microliter, and the detection sensitivity of a test paper method can reach 102 copies/microliter. In addition, according to the system, expensive test equipment does not need to be operated in a standard professional laboratory, and field detection of clinical samples can be achieved through the portable visual transverse flow test strip.
BOPI
Sede Electrónica
