Alerta

MOTORIZED STATIONARY EXERCISE APPARATUS

Resumen de: US20260283888A1

0000 A motorized stationary exercise apparatus includes a motor-driven pedal assembly, at least one sensor configured to measure rider interaction, a personalized exercise planning system, and a control system configured to dynamically personalize operation of the apparatus. The control system generates and continuously updates a rider-specific adaptive performance model that predicts future rider performance. Target motor operating parameters for each exercise session are determined by the personalized exercise planning system to optimize a rider performance objective function, and the electric motor dynamically adjusts pedal speed and torque during and across exercise sessions. The system may implement model-based predictive control, model-free estimation including artificial neural networks, or reinforcement learning or extremum seeking control. The adaptive model may estimate latent rider state variables including fatigue, endurance, strength, or neuromotor capability. The apparatus supports rehabilitation, neurological therapy, performance training, neuromotor entrainment, remote monitoring, multi-device coordination while incorporating safety detection and automatic torque reduction mechanisms.

GRIDEYE SENSOR

Resumen de: US20260287432A1

0000 The disclosed advanced ear infection detection device enhances diagnostic accuracy and efficiency, particularly for acute otitis media. A grid array infrared sensor offers both contact and non-contact options while integrating traditional temperature measurements. The device employs algorithmic calibration and data analytics to refine detection accuracy, ensuring precise, real-time assessments. Its wide-surface infrared scanning improves data collection, reducing diagnostic errors and streamlining the process. With rapid, reliable readings in seconds, it minimizes patient discomfort and seamlessly integrates into various healthcare settings, including pediatrics and emergency care. By addressing the limitations of conventional methods, this innovation sets a new standard in medical diagnostics, leveraging technology to improve.

RESPIRATORY CYCLE ONSET DETECTION

Resumen de: US20260283479A1

0000 Pulse data including a plurality of heart pulse samples of a user during a time window may be received from a wearable physiological monitor worn by the user. The pulse data may be mapped into a feature space that encodes individual heart pulse samples according to respiratory cycle stage. A first estimated respiratory waveform of the user during the time window may be generated from the pulse data mapped to the feature space and a plurality of respiratory onsets for the user during the time window calculated based on a plurality of local extrema of the first estimated respiratory waveform. Motion data may also be used, either alone or in a multi-model system, to evaluate user respiration.

METHOD AND SYSTEM FOR DETERMINING A POSITION OF A MARKER MEMBER

Resumen de: WO2026195199A1

A method for determining a position of a marker member for alignment of a surgical handpiece is provided. The surgical handpiece has an imaging unit releasably attached thereto and being configured to detect the marker member. The surgical handpiece further has a probe comprising a probe tip arranged at a defined position relative to the imaging unit. The method comprises providing the marker member at a fixed position relative to a dental and/or cranio-maxillofacial structure of a patient. The method comprises obtaining a data set indicative of a shape of a landmark and a position of the landmark relative to the marker member. The method comprises determining whether the data set meets one or more data collection criteria. The method comprises, upon the data set meeting the one or more data collection criteria, matching the data set to a digital model of the dental and/or cranio-maxillofacial structure. The method comprises mapping the position of the marker member to the digital model of the dental and/or cranio-facial structure based at least in part on the data set.

MULTI-SITE MEDICAL SENSOR

Resumen de: WO2026196154A1

The techniques of this disclosure generally relate to multi-site medical sensors that can be repositioned to multiple sites on a patient. A multi-site sensor includes a flexible substrate with physiologic sensing elements responsive to physiologic characteristics of the patient, and a deflection sensor responsive to deflection of the sensor about a folding axis. The measured deflection is used to determine the location of the sensor on the patient.

IMAGING CAMERA, MOBILE APPLICATION, AND HEALTH MONITORING SYSTEM

Resumen de: WO2026198701A1

A health monitoring system is disclosed that includes a handheld intraoral imaging device, a mobile computing device executing a mobile application, and a multi-layer artificial intelligence (AI) analysis framework. The handheld intraoral imaging device includes an image sensor, lens assembly, illumination sources, wireless communication module, processor, and memory, and is configured to capture intraoral image data and transmit the image data to the mobile computing device. The AI analysis framework is executed by at least one of the handheld intraoral imaging device and the mobile computing device. The AI analysis framework filters non-relevant or low-quality images, identifies anatomical regions within retained images, associates retained images with specific teeth or oral regions, and generates longitudinal condition indicators by comparing historical and current image data. The mobile application presents the longitudinal condition indicators to a user to support oral health monitoring and risk-awareness.

SYSTEM FOR SLEEP MONITORING, HEALTH STATUS DIAGNOSIS, AND MONITORING OF EXTRAVASATION AND METHODS OF USE

Resumen de: US20260283496A1

0000 Systems and methods are providing for detecting and monitoring respiratory, cardiac and/or sleep trend or status, and cardiopulmonary coupling in real time, wherein data obtained from a non-invasive electrode patch is analyzed using analysis algorithms for an electrical equivalent model that have been personalized for a patient's physiologic characteristics, medical condition and/or historical medical information using machine learning trained on a dataset representative of a large and diverse patient population. The systems and methods provide a simple, real-time, highly sensitive and specific, non-invasive, bedside solution for fluid level assessment, checking for increased air trapping, and ventilation assessment. The methods described include a variety of use cases for the inventive system and methods.

Systems and Methods For Monitoring Compliance with Recovery Goals

Resumen de: US20260290553A1

Systems and methods for incentivizing a user to satisfy a goal for attending twelve step meetings. The method includes the steps of: providing the user with a mobile device; detecting the presence of the mobile device at a first location and at a first time selected by the user; comparing the first time and the first location to a database of approved meetings, wherein the comparing is substantially contemporaneous with the first time; and providing a reward to the user upon confirming that: i) the first time and the first location correspond to an approved meeting; and ii) the user is proximate the mobile device at the first time.

METHODS, APPARATUS AND COMPUTER-READABLE MEDIA RELATING TO TREATMENT PLANNING

Resumen de: WO2026193911A1

A computer-implemented method performed by a radiotherapy treatment-planning client device, the method comprising: receiving, from a load-balancing server, address information for one or more available radiotherapy treatment-planning processing servers; in a first mode of operation: upon receiving a user command to perform a radiotherapy treatment-planning task, communicating with the load-balancing server to select one of the one or more available radiotherapy treatment-planning processing servers; in a second mode of operation: upon receiving a user command to perform a radiotherapy treatment-planning task, selecting one of the one or more available radiotherapy treatment-planning processing servers based on the received address information; and in the first and second modes of operation, communicating with the selected radiotherapy treatment-planning processing server to perform the radiotherapy treatment-planning task.

TECHNIQUE FOR DEFINING AN ORIENTATION OF A MODEL OF AN ANATOMY OF A PATIENT'S DENTAL ARCH WITHIN A GLOBAL REFERENCE FRAME

Resumen de: US20260283762A1

0000 A method for defining an orientation of an origin of a model of an anatomy of a patient's dental arch (302; 402) within a global reference frame comprises receiving a dataset comprising a surface mesh, defined by a plurality of polygon, representing the surface of the dental arch (302; 402). For each polygon, a exterior normal vector is determined. A vector sum of exterior normal vectors defines a normal vector, and thereby an orientation, of an occlusion plane (412). A first rotation angle is determined for aligning the normal vector of the occlusion plane (412) with a first direction of the reference frame. An anterior side (504) of the dental arch (302; 402) is defined based on geometric properties of the surface mesh. A second rotation angle is determined for aligning an anterior-posterior direction of the dental arch (302; 402) with a second direction of the reference frame.

METHOD OF AND SYSTEM FOR PATIENT CARE

Resumen de: WO2026198389A1

Disclosed is a method of patient care based on a digital twin that includes comparing a determined first parameter and a predicted first parameter. The determined first parameter is based on a signal and the predicted first parameter is based on the second parameter. If the comparing is false, that is, the determined first parameter does not correspond with the predicted first parameter, then the method includes defining a first condition.

SYSTEM AND METHOD FOR DETECTION OF PREMATURE VENTRICULAR CONTRACTIONS ARRHYTHMIAS BASED ON INTERNET-OF-THINGS

Resumen de: US20260290582A1

0000 A system and method for performing Internet-of-Things (IoT)-based detection of Premature Ventricular Contractions (PVC) arrhythmias includes electrocardiography (ECG) signal acquisition circuitry attached to a patient's body to acquire an ECG signal from the patient. The system includes IoT-based signal transmission circuitry using IoT communication to transmit the ECG signal to a Fog-network-based signal processing circuitry. The Fog-network-based signal processing circuitry uses a Fog network to apply a modified Pan and Tompkins algorithm to extract ECG features in frequency domain and time domain from the ECG signal; determine whether the patient has PVC arrhythmias, based on the extracted ECG features, provide an alert to the patient and a healthcare team upon determining that the patient has the PVC arrhythmias. The extracted ECG features include QRS complex durations, R-peaks, R-R intervals, an average of the R-R intervals, and an average deviation of the R-R intervals.

EMOTIONSBASIERTES DATENANALYSESYSTEM ZUR BENUTZEREMOTIONSÜBERWACHUNG UND BETRIEBSVERFAHREN DAFÜR

Resumen de: DE102025137937A1

Emotionsbasiertes Datenanalysesystem zur Benutzeremotionsüberwachung (1000), aufweisend: einen Datenspeicher (210), der einen vordefinierten Fragensatz (211-1 bis 211-N) und ein Emotionsmuster (212-1 bis 212-N) einer gesunden Person speichert, eine Szenariosteuereinrichtung (220), die Fragen sequenziell ausführt und einen Antworterlangungs-Startzeitpunkt und einen Antworterlangungs-Endzeitpunkt eines Benutzers (100-1) steuert, eine Vorverarbeitungsvorrichtung (230), die Elemente von Daten erhält, die eine Emotion des Benutzers (100-1) anzeigen, um vorverarbeitete Daten zu erzeugen, eine Individuelle-Emotion- Extraktionsvorrichtung (240), die eine Valenz und Erregung vorhersagt, eine Endgültige-Emotion-Ermittlungsvorrichtung (250), die vorhergesagte Werte der Valenz und der Erregung analysiert und den berechneten Wert als eine endgültige repräsentative Emotion primär extrahiert, eine Benutzeremotionsmuster-Analysevorrichtung (260), die die primär extrahierte endgültige repräsentative Emotion mit dem Emotionsmuster (212-1 bis 212-N) einer gesunden Person vergleicht und eine endgültige repräsentative Emotion sekundär extrahiert, und eine Anormale-Daten-Speicher-Servervorrichtung (310), die die sekundär extrahierte endgültige repräsentative Emotion empfängt und speichert.

Verfahren zur Herstellung dopaminerger neuronaler Organoide (d-NOs) und deren Verwendung zur Behandlung der Parkinson-Krankheit

Resumen de: DE102025111075A1

Die vorliegende Erfindung betrifft ein Verfahren zur Herstellung von dopaminergen neuronalen Organoiden (d-NOs) mit Nachweis der Dopaminfreisetzung in biologisch wirksamen Konzentrationen. Darüber hinaus umfassen d-NOs neben dopaminergen Neuronen auch funktionell miteinander verbundene GABAerge, glutamaterge und cholinerge Neuronen sowie Gliazellen, wodurch sie zu einem multizellulären Organoid mit einer für das Mittelhirn repräsentativen Zellzusammensetzung und Funktion werden. Daher zeigen die d-NOs der Erfindung eine komplexe Regulation dopaminerger Neuronen durch verwandte exzitatorische und inhibitorische Neuronen, was auf Kontrollmechanismen hindeutet, die beispielsweise eine Überproduktion und Freisetzung von Dopamin verhindern können. Die Erfindung bezieht sich auch auf die n-NOs als Implantat oder zur Verwendung bei der Behandlung der Parkinson-Krankheit. Darüber hinaus bezieht sich die Erfindung auf die Verwendung der d-NOs für Wirkstoffscreenings.

WEARABLE COMPUTING DEVICE WITH OPTICAL AND EEG SENSORS AND APPLICATIONS FOR THE WEARABLE COMPUTING DEVICE

Resumen de: WO2026193588A1

According to an aspect, there is provided a flexible wearable band comprising: a plurality of EEG sensors configured to measure electrophysiological signals, at least one light emitter positioned within a center the central EEG sensor, at least one optical sensor to measure optical signals in close proximity to the at least one light emitter, and an electronics module connected to the band. The at least one optical sensor and at least one of the plurality of EEG sensors are arranged in close proximity for co-located measurement. In some embodiments, the EEG sensors and/or the at least one optical sensor are positioned on the left and right hemispheres for measuring brain states associated with symmetric indexes.

METHOD FOR GENERATING EXERCISE GUIDE INFORMATION BY USING ARTIFICIAL INTELLIGENCE MODEL

Resumen de: WO2026197586A1

According to an embodiment of the present disclosure, disclosed is a method performed by a computing device and generating exercise guide information by using an artificial intelligence model. The method may comprise the steps of: acquiring at least one among force information related to a user's body, appearance information about the user's body, or movement information about the user's body; on the basis of at least one among the force information related to the user's body, the appearance information about the user's body, or the movement information about the user's body, generating an embedding by using a first artificial intelligence model; and generating, on the basis of the embedding, exercise guide information for the user by using a second artificial intelligence model.

SYSTEMS AND METHODS FOR MONITORING SLEEP PROFILES

Resumen de: WO2026193582A1

Systems and methods for monitoring sleep profiles are disclosed. A processor is operable to: obtain, from a practitioner computing device, initial sleep profile data for a patient; apply a sleep profile classification model to the initial sleep profile data to generate a proposed sleep classification; receive, from the practitioner computing device, an initial sleep classification in response to the proposed sleep classification being displayed at the practitioner computing device; based on the initial sleep classification, identify a sleep characteristic to monitor. The processor is operable to receive monitoring data related to the identified sleep characteristic; automatically generate current sleep profile data; generate an updated proposed sleep classification; compare the proposed sleep classification with the initial sleep classification; in response to detecting the updated proposed sleep classification does not match the initial sleep classification, automatically generate a progress update; and transmit the progress update to the practitioner computing device.

METHODS AND SYSTEMS FOR DETECTING SLEEP APNEA

Resumen de: WO2026199000A1

A polysomnography system comprises a pillow with a sensor and a fluid-filled chamber that dampens mechanical vibrations from a subject's environment. The sensor includes an accelerometer that converts vibrations into electrical ballistocardiogram signals representing head movement caused by heartbeats. A computing device with processors and memory receives these signals via a communication interface. The device applies signal processing to extract features indicative of respiratory events and uses a trained neural network to estimate an apnea-hypopnea index by detecting apnea and hypopnea events. Based on this index, the system transmits data to a remote server or stores it in a database.

MOUTH-THROAT MODELS FOR THE ASSESSMENT OF REGIONAL DEPOSITION OF INHALED PHARMACEUTICAL AEROSOLS

Resumen de: US20260290207A1

0000 Airway models and sets of airway models capture anatomical morphologies of mouth-throat geometries. The models capture intersubject variability. In addition, a method of predicting deposition of a nebulized hygroscopic aerosol in at least one pediatric oral airway involves determining or receiving one or more airway geometries from the one or more medical images including at least one characteristic dimension of an oral airway and an airway volume; determining or receiving one or more delivery conditions for the nebulized hygroscopic aerosol; calculating multiple nondimensional parameters such as Tidal Volume/airway volume ratio (TV/V), Stokes (Stk) number, Reynolds (Re) number, and Schmidt (Sc) number; and determining deposition in the oral airway using the TV/V, Stk, Re, and Sc numbers.

METHODS AND DEVICES FOR MAKING CUSTOMIZED PADS FOR DENTAL APPLIANCES

Resumen de: US20260283763A1

0000 A method of making and shipping or delivering an impression of a gum facing portion of a dental appliance includes pressing the gum facing portion of the dental appliance against a putty in an impression container. The method also includes allowing the putty to harden to make the impression and removing the dental appliance from the impression after the putty has hardened. The impression container with the impression of the gum facing portion of the dental appliance is then shipped or delivered.

Muffel, Aufbau, Verfahren und System zur Herstellung eines Dentalbauteils

Resumen de: DE102025110966A1

Die vorliegende Erfindung betrifft eine Muffel, einen Aufbau und ein Verfahren zur Herstellung eines Dentalbauteils, insbesondere eines Zahnersatzes oder eines - teilersatzes. Die Muffel weist zumindest eine Kavität auf, die eine Negativform des herzustellenden Denktalbauteils ist, und zumindest einen Kanal, der mit der Kavität in Verbindung steht. Die Muffel weist eine erste Stirnseite und eine zweite Stirnseite auf, die an einander gegenüberliegenden Enden der Muffel angeordnet sind, wobei die erste Stirnseite eine Öffnung aufweist, die mit dem Kanal in Verbindung steht, und wobei an die erste Stirnseite zumindest eine Erhebung angeformt ist, die sich von der ersten Stirnseite erstreckt.

Dentale geschichtete Prothesen sowie die Herstellung einer geschichteten dentalen Prothese

Resumen de: DE102025111350A1

Gegenstand der Erfindung ist eine dentale geschichtete Prothese, umfassend mindestens einen inneren Zahnbereich und mindestens eine, den inneren Zahnbereich teilweise bis vollständig umgebende Zahnschicht, und optional mindestens eine Zahnhalsschicht sowie ein Verfahren zu deren Herstellung als auch ein Computerprogrammprodukt zur Herstellung der Prothese.

SYSTEM AND METHOD FOR THREE-DIMENSIONAL PRINTING OF COLLIMATOR

Resumen de: US20260284968A1

0000 A method for forming a metallic grid structure includes utilizing 3D printing for printing a first layer of a first wall section of the metallic grid structure in a first direction along a first vector offset from a center line of the first wall section by half of a first distance of a first width of the first wall section that is orthogonal to the center line. The method also includes utilizing 3D printing for printing a second layer of the first wall section on the first layer in a second direction along a second vector offset from the first line of the first wall section by half of the first distance of the first width of the first wall section, wherein the second direction is opposite the first direction, and the first vector and the second vector are disposed on opposite sides of the center line.

ORTHOPAEDIC KNEE JOINT PROSTHESIS

Resumen de: US20260283809A1

0000 An orthopedic knee joint prosthesis includes a metallic femoral implant part, a metallic tibial implant part, and a meniscus replacement part. The femoral implant part and in particular also the tibial implant part are manufactured additively by metallic 3D printing. The femoral implant part and/or the tibial implant part have/has a three-dimensionally porous surface structure formed by the 3D printing, in surface regions configured to face the bone, to allow incorporation of the bone into the implant part. The femoral implant part and/or the tibial implant part have/has at least in some areas a coating in surface regions configured to not be in contact with the bone and not be in contact with the meniscus replacement part but configured to be in contact with soft tissue. The coating reduces a surface roughness of the surface regions.

MEDICATION DELIVERY DEVICE CONNECTION TECHNIQUES

Nº publicación: US20260290537A1 24/09/2026

Solicitante:

ELI LILLY AND CO [US]
Eli Lilly and Company

Resumen de: US20260290537A1

0000 A method is provided for presenting information from a particular medication delivery device to a user. The method includes: receiving a set of advertising packets, the set of advertising packets comprising at least one advertising packet from one or more medication delivery devices, the one or more medication delivery devices including the particular medication delivery device, wherein each advertising packet includes an identifier associated with a respective medication delivery device of the one or more medication delivery devices; determining a number of unique identifiers included in the set of advertising packets to determine a number of transmitting medication delivery devices; determining, based on the number of transmitting medication delivery devices, whether to prompt the user to provide identification information for the particular medication delivery device; and presenting the information from the particular medication delivery device to the user.