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SYSTEMS AND METHODS FOR CONTROLLING BREATHING ASSISTANCE DEVICES BASED ON PHENOTYPE-SPECIFIC MODELS

Resumen de: WO2026188343A1

Various methods, devices and systems for providing personalized breathing assistance for a user and controlling breathing assistance devices based on phenotype-specific models are described herein. The methods involve receiving at least one polysomnography signal associated with user, identifying one or more apnea-related events in the polysomnography signal, determining an apnea signature for the user based on the identified one or more apnea-related events, projecting the apnea signature for the user onto a cluster plot. The cluster plot includes clusters that include apnea signatures of other users where the clusters represent corresponding phenotypes. The methods further involve identifying a phenotype for the user based at least on a location of the projected apnea signature in the cluster plot relative to each of the clusters determining the phenotype-specific breathing assistance model associated with the identified phenotype for the user.

MENTAL STRATEGY REPRESENTATION

Resumen de: WO2026190776A1

A method for generating a sensory representation of a mental strategy used during a mental treatment, including: receiving by a system input information, wherein the input information comprises information about at least one mental treatment delivered to a subject and information about at least one mental strategy used by the subject during the mental treatment, wherein the mental treatment is configured to modify a subject state; generating by the system a sensory representation of the at least one mental strategy based on the received input information; and providing the sensory representation by the system to the subject.

METHODS AND SYSTEMS FOR PATIENT STRATIFICATION

Resumen de: WO2026190756A1

Provided are methods, systems, and kits for analyzing genetic data and transcriptomic data derived from a sample of a subject with a trained machine learning algorithm to determine a degree of bladder cancer risk in the subject.

A TRANSFORMER-BASED AI MODEL FOR SEIZURE ONSET ZONE LOCALIZATION IN STEREO-EEG RECORDINGS

Resumen de: WO2026193134A1

The present disclosure relates to machine learning systems and methods for locating seizure onset zones and tasks related to stereotactic electroencephalogram (SEEG) data. Latent features that capture intrinsic structure within SEEG signals can be identified, and used to classify SEEG channels as corresponding to epileptogenic or non‑epileptogenic regions and/or used for distinguishing ictal patterns associated with neuromodulation therapies, comparing electrophysiological signatures across different diagnostic modalities, grouping or stratifying patients, and/or integrating with structural or functional imaging datasets to facilitate multimodal localization of epileptogenic networks. An example method of the present disclosure includes obtaining EEG or SEEG data, performing a time-frequency decomposition, extracting one or more features from the spectral data, encoding a time and determining a sequence of the detected features, generating a multidimensional vector based on the determined sequence of features, and classifying one or more dimensions of the multidimensional vector.

METHOD AND APPARATUS FOR PRODUCING POLYGLUTAMIC ACID FILLER

Resumen de: US20260273133A1

The present invention provides a method for manufacturing polyglutamic acid (PGA) fillers or implants comprising: preparing the main material, polyglutamic acid, and a reinforcing material, hyaluronic acid (HA); mixing said PGA and said HA together with a solvent containing water to prepare a mixed solution; feeding said mixed solution to a hot extrusion device; extruding said mixed solution through a nozzle of said hot extrusion device; and sterilizing said extruded mixed solution.

SYSTEMS AND METHODS FOR AUTOMATED HYDROGEL INJECTION MOLDING BIOMANUFACTURING

Resumen de: WO2026193448A1

Methods for automated biomanufacturing of hydrogel cell macroencapsulation devices having complex geometries are disclosed. First and second components may be introduced into a microfluidic mixer and undergo mixing flow such that they combine to form a gelling alginate solution. Cells may be incorporated into the gelling alginate solution after mixing and centered in the gelling alginate solution through the use of laminar flow. The cell incorporated gelling solution is then injected into a three-dimensional hydrogel mold to form the hydrogel cell microencapsulation device.

DENTAL MODELING DEVICE AND METHOD

Resumen de: US20260272619A1

0000 Various embodiments disclosed relate to imaging and analysis of a patient's dental arch. A 3D model and a selection of correlated 2D images are presented to a practitioner. One or more of the 2D images include highlighted borders to alert the practitioner when an alternate image can be selected to improve information concerning a feature of interest.

INFUSION PUMP DISPOSABLE CHARACTERIZATION AND COMPATIBILITY

Resumen de: US20260273181A1

0000 Certain aspects of the disclosure provide systems and methods for detecting compatibility between infusion systems and infusion administration sets, in particular between infusion administration sets and infusion fluids. Some methods include determining information characterizing the infusion administration set and detecting at the infusion device, compatibility between the infusion administration set and the fluid based on the information characterizing the infusion administration set.

System and Method for Real-Time Animal Training and Welfare Management

Resumen de: US20260271879A1

Disclosed embodiments provide a system and method for adaptive real-time animal training and welfare management, utilizing non-invasive neural monitoring and cognitive assessment via machine learning. The system includes conductive polymer ink electrodes or specialized wearable headgear for continuous acquisition of neural signals. Advanced algorithms perform frequency-domain analysis to correlate specific neural profiles with cognitive states such as attentiveness and stress. A multi-layered machine learning framework interprets these signals, dynamically adjusting training protocols and welfare assessments. Integrated environmental sensors enable multimodal data fusion, refining contextual accuracy. This invention supports continuous data-driven optimization of training efficacy, animal welfare, and predictive performance analytics throughout the animal’s lifecycle.

MODULE LOCATION REPORTING

Resumen de: US20260273169A1

Certain aspects of the disclosure provide systems and methods for detecting coupling of multiple infusion devices and determining a connection position of the coupled infusion devices relative to one another. Coupling data may be used to indicate usage, or overuse, of the connection position. Such usage information may be used to determine when the infusion device is ready for maintenance, cleaning, repair, and/or maintenance. Further, such usage information may be used to generate a configuration recommendation to balance and distribute usage across various connection positions of the infusion device.

TECHNIQUES FOR AUTOMATED REMOVAL OF SUPPORT ELEMENTS FROM A PRINTED ALIGNER

Resumen de: WO2026190648A1

The present technology uses an additive manufacturing process to prepare aligners designed for a treatment plan. An aligner is built on support elements extending from a platform formed on a building plate using an additive manufacturing process. The building plate, optionally, can have a reference feature. The aligner is oriented such that the gingival surface of the aligner is facing the building platform. The support elements are positioned such that the support elements only contact the border of the gingival surface. When completed, the aligner can be cut away from the support elements along the gingival line of the aligner.

URETHANE MONOMERS; CURABLE COMPOSITIONS; AND ACID-REINFORCED URETHANE POLYMERS THEREOF

Resumen de: WO2026192903A1

Disclosed herein are urethane monomers, acidic monomer, monovinyl multiurethane monomers, monourethane multivinyl monomers, and oligomeric clustered urethanes; curable compositions thereof; and acid-reinforced urethane polymers.

SURGICAL ACCESSORIES FOR OPTIMIZED 3D SCANNING AND REGISTRATION

Resumen de: WO2026193094A1

A structured light 3D scanning system designed for intraoperative surgical use, with a novel method to improve registration accuracy while reducing computational cost is described. The system utilizes a light source to project structured light patterns onto the surgical site, generating a 3D point cloud that can be used, for example, to align preoperative CT data, aid in surgical planning decisions, and verify the accuracy of planned resections. Modified Surgical Field Materials (SFMs) are described that optimize registration accuracy, reduce computational load, and streamline surgical workflows, making structured light scanning more reliable and effective for precision-based procedures such as orthopedic, neurosurgical, and other complex surgical interventions. The present disclosure further provides a drape system designed to maintain a sterile field during the operation of a structured light 3D scanner by covering unsterilized hardware components while preserving the optical integrity necessary for accurate scanning.

STERILIZED FIBRILLAR COLLAGEN BIOINK AND SCAFFOLDS COMPRISING IT

Resumen de: WO2026190308A1

Sterilized fibrillar collagen bioink and scaffolds comprising it It relates to a collagen bioink sterilized by ionizing radiation, which has a storage modulus equal to or lower than 50000 Pa, wherein the sterilized collagen bioink is an aqueous suspension comprising: i) a mass of native Type I collagen fibers, wherein the 5 concentration of collagen is from 0.1 to 10% by weight with respect to the total bioink weight; and at least 90% of the total mass of the fibers have a length equal to or lower than 3500 μm and a fiber diameter equal to or lower than 150 μm measured at pH from 1 to 2; and ii) one or more additives capable of controlling the storage modulus of the collagen bioink when it is sterilized such that the storage modulus of the sterilized bioink is 0 at most 200% of the storage modulus of the non-sterilized bioink. It also relates to process for the preparation of the sterilized collagen bioink, the use of the bioink for printing 3D scaffolds, and to the scaffolds comprising the bioink.

VISION-BASED SCENE SEGMENTATION AND ACTION CLASSIFICATION

Resumen de: US20260272266A1

0000 This disclosure provides methods, devices, and systems for classifying video frames. The present implementations more specifically relate to vision-based scene segmentation and action classification. In some aspects, a machine learning model may be trained to infer, from images or video captured by a camera disposed on the distal end of a medical instrument (such as a scope), information about a working channel instrument and/or other objects in a field-of-view (FOV) of the camera. In some implementations, a first machine learning model may be trained to extract features associated with an object (such as a working channel instrument, an anatomy, or a target within the anatomy) from one or more frames of video depicting the object, and a second machine learning model may be trained to infer an action associated with the object, for each frame of the one or more frames, based on the features extracted from the frame.

CONTINUOUS AMBULATORY PERITONEAL DIALYSIS (CAPD) DEVICE WITH SOLENOID ACTUATED OCCLUSION

Resumen de: WO2026190680A1

Apparatus, systems, and methods for a solenoid-actuated and low-cost device for automating at least part of a continuous ambulatory peritoneal dialysis (CAPD) therapy are provided. A CAPD device includes a front housing, a rear housing, a central bracket, and a cover configured to surround a Y-junction of a CAPD tubing set. The CAPD device further includes first and second solenoids configured to move first and second occlusion tips between depressed and extended positions. The occlusion tips are configured to occlude a dialysis fluid line and a drain line of the CAPD tubing set to achieve a drain cycle, a fill cycle, and/or a dwell cycle.

SYSTEMS AND METHODS FOR MEDICAL DEVICE MODULE DETECTION

Resumen de: US20260273171A1

0000 Certain aspects of the disclosure provide systems and techniques for operating medical devices. An example method includes obtaining over a period of time, an inrush current of one or more hardware modules connected to the process control unit; determining a respective type of each of the one or more hardware modules based on the inrush current; and operating the process control unit based on the respective type of each of the one or more hardware modules.

ACCURATE SCANNING OF REFLECTIVE OBJECTS

Resumen de: US20260272621A1

A method includes receiving intraoral scan data generated by an intraoral scanner, the intraoral scan data comprising one or more images of a reflective intraoral object generated during projection of light onto the reflective intraoral object by a light projector of the intraoral scanner. The method further includes identifying a virtual image of the light projector in the one or more images caused by reflection of the light off of the reflective intraoral object. The method further includes determining at least one of a position or an angle of a surface of the reflective intraoral object based at least in part on the virtual image of the light projector identified in the one or more images.

BLOOD GLUCOSE INSIGHT GENERATOR FOR DRIVING APPLICATIONS

Resumen de: US20260272353A1

0000 Systems and methods are described for monitoring blood glucose when driving. The methods may include receiving blood glucose input for a user over a time period, detecting one or more driving events associated with the user over the time period, correlating the blood glucose input with the one or more driving events; determining, based on the correlation, at least one pattern indicating a blood glucose status for the user, generating, based on the blood glucose status and a repository of user data, at least one insight or trend corresponding to the user, and causing presentation of the at least one insight or trend.

ANALYSIS OF AMBIENT SPEECH FOR HEALTH CONDITIONS USING VOCAL BIOMARKERS

Resumen de: US20260279386A1

Disclosed herein are techniques for diagnosing health conditions of a subject based on the subject's vocal biomarkers, including techniques for generating one or more models (e.g., machine learning models) trained to predict a health condition in multiple subjects. One or more techniques may include receiving ambient audio data, segmenting the ambient audio data by speaker to form speech data samples for a given speaker, filtering the speech data of the given speaker to remove irrelevant or insignificant portions, coalescing filtered speech data to form speech data that satisfies a predetermined threshold of speech data, analyzing the input speech data using one or more trained models, and outputting the prediction of whether the given speaker has any of the one or more health conditions.

DEPLOYABLE BISTABLE AUXETIC EXPANDABLE INTERBODY SPACER

Resumen de: US20260272665A1

An implant can be configured to transition between a first stable state and a second stable state. The implant can include a first surface and a second surface coupled to the first surface. The first surface can include a first structure configured to form a stable planar shape during the first stable state of the implant and to form a stable three-dimensional (“3D”) shape during the second stable state of the implant. The second surface can include a second structure configured to form a stable planar shape during the first stable state of the implant and to form a stable 3D shape during the second stable state of the implant.

TECHNIQUES FOR SIMULTANEOUSLY RUNNING DISCRETE IMAGING MODALITIES

Resumen de: US20260281548A1

0000 A system and processing techniques for simultaneously analyzing multiple imaging modalities. The discussed technique can include capturing a combined image stream including a first modality stream and at least a second modality stream. The technique continues by analyzing the first modality stream with a first analysis module and, concurrently, analyzing a second modality stream with a second analysis module. The combined image stream can be generated using timed lighting modalities to generate interleaved image streams or by extracting narrow color bands from a primary color sensor.

SYSTEMS AND METHODS TO MAP AUTOREGULATION OF THE KIDNEY USING MAGNETIC RESONANCE IMAGING

Resumen de: US20260278800A1

A method of mapping autoregulation of a kidney using magnetic resonance (MR) imaging is provided. The method includes acquiring a time series of MR images of a subject while the subject is at rest by acquiring MR images of an imaging region repeatedly over a period of time by applying a pulse sequence. The imaging region includes at least a kidney of the subject. The method also includes analyzing the time series of MR images along a temporal dimension, and identifying features associated with autoregulation of the kidney including tubuloglomerular feedback (TGF) in voxels of the MR images based on the analysis. The method further includes generating a map and/or a metric of the autoregulation based on the identified features, and outputting the map and/or the metric.

APPARATUS AND METHOD FOR TREATMENT OF A TARGET AREA

Resumen de: US20260273308A1

0000 The present invention relates to an apparatus for treatment of a target area of a patient by an energy beam. The apparatus comprises means for receiving at least one 3D image of the target area; means for delivering the energy beam to at least a portion of the target area and means for automatically moving the energy beam, preferably by moving at least a portion of the means for delivering the energy beam, such that energy is delivered essentially uniformly across the target area. In particular, the apparatus is adapted to control, during the moving of the energy beam, an effective distance of the means for delivering the energy beam and/or an orientation of the energy beam relative to the target area, at least in part based on the at least one 3D image of the target area.

CHILD EVALUATION SYSTEM AND METHOD OF USE

Nº publicación: US20260279543A1 17/09/2026

Solicitante:

GUNDUZ SUSAN O [US]
DENTON STEPHANIE ANNE [US]
Gunduz Susan O.
Denton Stephanie Anne

Resumen de: US20260279543A1

Systems and methods for the diagnosis and treatment of developmental delay and/or disorders in children for the purpose of early diagnosis and treatment of children to promote the development of at least one of fine motor skills, gross motor skills, sound articulation and sound discrimination skills, receptive language, expressive language, phonological awareness, phonological processing to prevent reading failure, academic underachievement, color blindness, attention issues and social emotional dysregulation. The systems and methods resulting in the generation of a referral of the individual for services in areas where the evaluation results were deficient to promote at least one of fine motor skills, gross motor skills, sound articulation, and sound discrimination skills.