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ERNA molecular marker for auxiliary diagnosis of Crohn disease and application of eRNA molecular marker

Nº publicación: CN119061137A 03/12/2024

Solicitante:

THE FIRST AFFILIATED HOSPITAL OF NINGBO UNIV
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CN_119061137_PA

Resumen de: CN119061137A

The invention discloses an eRNA molecular marker for auxiliary diagnosis of Crohn's disease and application of the eRNA molecular marker, and is characterized in that the eRNA molecular marker is eRNA42767, and the nucleotide sequence of the eRNA molecular marker is shown as SEQ ID NO.1. The invention also provides application of the eRNA molecular marker in preparation of a kit for auxiliary diagnosis of Crohn's disease, and the kit comprises an eRNA42767 fluorescent quantitative PCR specific amplification primer, the nucleotide sequence of the upstream amplification primer is 5 '-CCTCTCTCTGGACATGCCTA-3', and the nucleotide sequence of the downstream amplification primer is 5 '-CCTATGCGTAGAGATTCTTGCC-3'. The kit has the advantages that early diagnosis of a patient suffering from the Crohn disease on the molecular level is conveniently, quickly and efficiently realized, the pertinence is strong, the specificity is strong, the sensitivity is high, and the kit is beneficial to early discovery and timely treatment of the Crohn disease.

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