Resumen de: WO2025085539A1
The present disclosure relates to engineering bacteria and methods for promoting barrier function in skin and mucosal surfaces. In particular, the disclosure is related to engineering bacterium to produce a delta hemolysin (delta toxin) peptide and methods of using the engineered bacteria or the delta hemolysin peptide for improving or maintaining gut health, regulating glucose metabolism, maintaining intestinal integrity, decreasing inflammation, modulating wound healing and tissue regeneration, and treating or preventing a disease or disorder.
Resumen de: WO2025084631A1
The present invention provides: a recombinant endolysin for inhibiting pathogenic Gram-negative bacteria, which exhibits excellent antibacterial activity against pathogenic Gram-negative bacteria, which, unlike Gram-positive bacteria, are difficult to access due to the formation of cell walls; and a use thereof.
Resumen de: WO2025081818A1
Provided in the present application is a bacteriophage lyase or a mutant thereof. The bacteriophage lyase comprises any one of the following: (1) an amino acid sequence as shown in SEQ ID NO. 1, or an amino acid sequence having at least 80% identity to the amino acid sequence as shown in SEQ ID NO. 1; and (2) a mutation in the amino acid sequence as shown in (1) having a polypeptide domain with cysteine and histidine-dependent aminopeptidase (CHAP) activity, a cell wall binding domain, and/or an amidase domain. The bacteriophage lyase described above has improved temperature stability and lytic activity against Staphylococcus aureus, and reduced dependence on refrigeration conditions, which can effectively avoid side effects caused by antibiotics. The bacteriophage lyase can be used for preventing or treating diseases caused by Staphylococcus aureus, inhibiting the growth of Staphylococcus aureus in the environment, production facilities, food or animal feed, and preventing and treating biofilms generated by Staphylococcus aureus.
Resumen de: AU2023366608A1
A bacterial composition for substrate inoculation to improve the fertility of the substrate comprises a predetermined concentration of at least one strain of autotrophic bacteria, wherein the autotrophic bacteria is characterised in having the ability to produce organic compounds in a predetermined substrate; and a predetermined concentration of at least one strain of mineral nutrient producing bacteria selected from a group including diazotrophic bacteria, potassium solubilizing bacteria and phosphate solubilizing bacteria, wherein the bacteria is characterised in having the ability to produce mineral nutrients in such predetermined substrate. The substrate inoculation of the autotrophic bacterial portion of the composition increases the production of metabolizable forms of organic compounds, and inoculation of the mineral nutrient producing bacterial portion of the composition metabolizes the increased organic compounds for an increased production of metabolizable forms of mineral nutrients in the predetermined substrate.
Resumen de: US2025129129A1
To control plant diseases caused by Xanthomonas spp., a novel bacteriophage exhibiting bacteriolysis activity specifically on Xanthomonas spp. was isolated. Thus, developed and provided is a plant disease control composition containing the bacteriophage as an active ingredient. Provided are a bacteriolytic agent containing a bacteriophage that has a novel genomic DNA sequence and exhibits bacteriolysis activity specifically on Xanthomonas spp., and a plant disease control composition containing the same as an active ingredient.
Resumen de: US2025127166A1
A technique useful in the field of agri-horticulture such as a technique for preventing pest damage to plants is provided. Pest damage to plants is prevented by using various glutamic acid derivatives.
Resumen de: US2025127177A1
The present invention relates to natural or natural-like analogues of insect pyrokinin neuropeptide Hy-NADEDQQQSVDFTPRL-NH2 (SEQ ID NO:2) having activity against insects, for example hemipteran, dipteran, lepidopteran, blattodean and/or coleopteran insects, such as aphids, moths and fruit flies, and their use as insect control agents (e.g. insecticides) and plant protection agents.
Resumen de: US2025127180A1
The present invention is directed to an anti-fungal composition including a plurality of particles including: at least one dsRNA molecule including a nucleic acid sequence complementary to at least one transcript of at least one essential gene of a fungus, and methods of using same.
Resumen de: US2025127179A1
The present invention relates to natural or natural-like analogues of insect pyrokinin neuropeptides and AKH neuropeptides, and combinations thereof, having activity against insects, for example hemipteran, dipteran, lepidopteran, blattodean and/or coleopteran insects, such as aphids, moths and fruit flies, and their use as insect control agents (e.g. insecticides) and plant protection agents.
Resumen de: US2025127176A1
The present invention relates to bio-fungicides that inhibits Phytophthora infestans. More particularly, the present invention relates to novel strains of Bacillus spp. that can inhibit Phytophthora infestans. The present invention also relates to bio-fungicidal formulations comprising novel strains of Bacillus spp. either alone or a mixture of novel strains of Bacillus spp., in combination with other excipients.
Resumen de: WO2025083314A1
The present invention provides a new bacterial strain of the genus Variovorax capable of oxidising elemental sulphur, generating sulphate. When added to a soil, the bacterium can transform the elemental sulphur present into sulphate, the main soluble form of sulphur that can be absorbed by roots, providing plants with more sulphur available for their metabolic needs, stimulating their growth, and the yield of their crops. The use of the bacterium is proposed, optionally with added elemental sulphur, to stimulate plant growth and/or to act as a biostimulant for plants, as well as to modify or restore soils, especially alkaline, limestone, or saline soils, since the activity of the bacterium generates a reduction in pH, enrichment with sulphates, structural modifications, an increase in porosity, solubilisation of phosphorus salts, and other modifications.
Resumen de: US2025127178A1
The present invention relates to natural or natural-like analogues of insect pyrokinin neuropeptide Hy-GGSMTFSPRL-NH2(SEQ ID NO:2) having activity against insects, for example hemipteran, dipteran, lepidopteran, blattodean and/or coleopteran insects, such as aphids, moths and fruit flies, and their use as insect control agents (e.g. insecticides) and plant protection agents.
Resumen de: US2025127136A1
Micropeptides (miPEPs), or peptides coded by microRNAs, for promoting nodulation between a plant and a bacterium, as well as their use in this manner.
Resumen de: EP4541170A1
The present invention is comprised in the field of agrobiotechnology. Specifically, the invention relates to a composition and a method for coating seeds which improves the germination thereof. The present invention also relates to a seed coated with the composition of the invention and to the use of said composition for coating seeds. The composition herein described consists of mycorrhizal fungi, bacteria of the genus Pseudomonas, a fungus of the genus Trichoderma, a water retainer, clay, an adherent, a fauna deterrent, and organic matter.
Resumen de: AU2023289032A1
The present invention is directed to an anti-fungal composition including a plurality of particles including: at least one dsRNA molecule including a nucleic acid sequence complementary to at least one transcript of at least one essential gene of a fungus, and methods of using same.
Resumen de: WO2023242812A1
The present invention relates to the use of at least one Streptomyces venezuelae strain, in particular the Streptomyces venezuelae DSM 33887 strain, as a phytopharmaceutical drug, in particular as a fungicide or bio-fungicide. A further object of the invention is a Streptomyces venezuelae strain referred to as DSM 33887, and compositions and uses thereof. The present invention relates to a method for the control of phytopathogens and a method to prevent, control, and treat plant diseases caused by phytopathogens, comprising the use of a Streptomyces venezuelae strain, preferably the DSM 33887 strain.
Resumen de: EP4541190A1
The present disclosure provides a plant disease resistance inducing agent that can effectively induce resistance to a plant disease. A plant disease resistance inducing agent according to the present disclosure contains a secretion product of a cyanobacterium.
Resumen de: EP4541191A1
This disclosure concerns Streptomyces spp. strains, isolated from different marine biotopes, able to inhibit the growth of Gnomoniopsis smithogilvyi (syn. Gnomoniopsis castaneae) (Gs). This fungus is the causal agent of chestnut brown rot responsible for damages in post-harvest fruits, and of wood cankers in the chestnut tree, and is responsible for massive losses in the chestnut sector. The actinobacterial extracts, as well as the corresponding strains, presented an excellent activity against Gs. These strains can be used in integrated and organic agriculture for biological control and integrated Gs management. This ability is of utmost importance in the context of the banning of several fungicidal substances.
Resumen de: EP4541356A2
This application provides and discloses anti-parasitic, anti-pest or insecticidal nucleic acid molecules and their calmodulin target genes for the control of arthropod parasites and pests. This application further provides methods and compositions for the control and treatment of parasites and pests in Apis mellifera (honey bee) hives.
Resumen de: US2021139551A1
Methods of breaking down a biofilm or inhibiting, preventing or treating a microbial infection that produces a biofilm are disclosed, which involves administration of a polypeptide that has one or more modified HMG-box 1 domains to a subject suffering from the infection or having the biofilm. By competing with microbial proteins that bind to DNA scaffold in the biofilm, these polypeptides destabilize the biofilm leading to destruction and removal of the biofilm by the immune system.
Resumen de: US2025122464A1
The present application relates to a novel microalgae strain with the efficacy of promoting plant growth and a use thereof. When cultured in the presence of fermentation exhaust gas, a novel Chlorella vulgaris CD02-3002 strain according to an aspect grows fast with a high efficiency of photosynthesis and thus can effectively reduce the exhaust gas generated by microbial fermentation. Having the effect of promoting plant growth when applied to plants, a culture of the strain or a supernatant of the culture can be used as a fertilizer for plants and thus can be advantageously applied as a novel carbon reduction technique.
Resumen de: WO2025076620A1
A biological agent releasing receptacle for releasing a biological agent in proximity of vegetation to be treated is provided. The biological agent releasing receptacle includes an elongated body with a receptacle wall defining a receptacle cavity configured to receive the biological agent therein. The elongated body includes a soil-contacting portion configured to be inserted into soil and a biological agent releasing portion located opposite the soil-contacting portion and configured to extend outwardly from the soil, away from the soil-contacting portion. One or more biological agent releasing opening is defined in the receptacle wall of the biological agent releasing portion to release the biological agent received in the receptacle cavity in proximity of the vegetation to be treated. Methods for preparing the biological agent releasing receptacle, as well as methods for installing the biological agent releasing receptacle, for instance in a crop, are also provided.
Resumen de: WO2025081186A1
Herein, Klebsiella pneumoniae phage cocktails comprising a lytic phage EKq1 newly isolated on Klebsiella quasipneumoniae are introduced. A 5 -phage cocktail KPM1 comprises five K pneumoniae phages including EKq1, EKq2, AFR4, KEN39, KEN42, and the efficacy of KPM1 phage cocktail is demonstrated in carbapenem-resistant K pneumoniae strain-infected mice model. Also, a 6-phage cocktail KPM1-1 is introduced, which further comprises EKp148 in addition to the five core KPM1 phages. The cocktails can be used as main ingredients of pharmaceutical compositions either alone or in combination with antibiotics. Also, methods of using the same for the treatment of respiratory infections caused by K pneumoniae are presented.
Resumen de: WO2025080749A1
Methods are provided for treating a pathogen infection or reducing the risk of developing a pathogen infection, reducing the severity and/or incidence of a pathogen infection of a plant or part thereof, and improving the growth and/or development of a pathogen-infected plant or part thereof comprising contacting the plant with an effective amount of a TOR (Target of Rapamycin) inhibitor.
Nº publicación: WO2025079634A1 17/04/2025
Solicitante:
SUMITOMO CHEMICAL COMPANY LTD [JP]
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Resumen de: WO2025079634A1
Provided is a compound having an excellent controlling effect against harmful arthropods. A compound represented by formula (I) wherein L represents a single bond, or the like; R1 represents a C1-C6 linear hydrocarbon group, or the like; R2 represents a 5- or 6-membered aromatic heterocyclic group, or the like; X represents NR11C(Z)R12, or the like; Z represents an oxygen atom, or the like; R11 represents a C1-C6 linear hydrocarbon group, or the like; R12 represents a phenyl group that may be substituted by one or more substituents, or the like; and Q represents a group represented by formula A1 (wherein # represents a binding position to 2, and ● represents a binding position to a carbon atom) or an N-oxide thereof has an excellent controlling effect against harmful arthropods.