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LastUpdate Última actualización 28/04/2025 [06:46:00]
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ENGINEERED BACTERIA FOR CELLULAR BARRIER MAINTENANCE AND PROTECTION

NºPublicación:  WO2025085539A1 24/04/2025
Solicitante: 
THE TRUSTEES OF COLUMBIA UNIV IN THE CITY OF NEW YORK [US]
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
WO_2025085539_A1

Resumen de: WO2025085539A1

The present disclosure relates to engineering bacteria and methods for promoting barrier function in skin and mucosal surfaces. In particular, the disclosure is related to engineering bacterium to produce a delta hemolysin (delta toxin) peptide and methods of using the engineered bacteria or the delta hemolysin peptide for improving or maintaining gut health, regulating glucose metabolism, maintaining intestinal integrity, decreasing inflammation, modulating wound healing and tissue regeneration, and treating or preventing a disease or disorder.

RECOMBINANT ENDOLYSIN FOR INHIBITING PATHOGENIC GRAM-NEGATIVE BACTERIA AND USE THEREOF

NºPublicación:  WO2025084631A1 24/04/2025
Solicitante: 
LYSINBIO CO LTD [KR]
\uC8FC\uC2DD\uD68C\uC0AC \uB9AC\uC2E0\uBC14\uC774\uC624
WO_2025084631_PA

Resumen de: WO2025084631A1

The present invention provides: a recombinant endolysin for inhibiting pathogenic Gram-negative bacteria, which exhibits excellent antibacterial activity against pathogenic Gram-negative bacteria, which, unlike Gram-positive bacteria, are difficult to access due to the formation of cell walls; and a use thereof.

BACTERIOPHAGE LYASE OR MUTANT THEREOF AND USE THEREOF

NºPublicación:  WO2025081818A1 24/04/2025
Solicitante: 
HONGKONG RISING BIOTECHNOLOGY CO LTD [CN]
SUZHOU READCRYSTAL BIOTECHNOLOGY CO LTD [CN]
\u9999\u6E2F\u745E\u661F\u751F\u7269\u79D1\u6280\u6709\u9650\u516C\u53F8,
\u82CF\u5DDE\u9752\u4E91\u745E\u6676\u751F\u7269\u79D1\u6280\u6709\u9650\u516C\u53F8
WO_2025081818_PA

Resumen de: WO2025081818A1

Provided in the present application is a bacteriophage lyase or a mutant thereof. The bacteriophage lyase comprises any one of the following: (1) an amino acid sequence as shown in SEQ ID NO. 1, or an amino acid sequence having at least 80% identity to the amino acid sequence as shown in SEQ ID NO. 1; and (2) a mutation in the amino acid sequence as shown in (1) having a polypeptide domain with cysteine and histidine-dependent aminopeptidase (CHAP) activity, a cell wall binding domain, and/or an amidase domain. The bacteriophage lyase described above has improved temperature stability and lytic activity against Staphylococcus aureus, and reduced dependence on refrigeration conditions, which can effectively avoid side effects caused by antibiotics. The bacteriophage lyase can be used for preventing or treating diseases caused by Staphylococcus aureus, inhibiting the growth of Staphylococcus aureus in the environment, production facilities, food or animal feed, and preventing and treating biofilms generated by Staphylococcus aureus.

BACTERIAL COMPOSITION AND METHOD FOR INOCULATION

NºPublicación:  AU2023366608A1 24/04/2025
Solicitante: 
EL I TECH PTY LIMITED
EL-I TECHNOLOGIES (PTY) LIMITED
AU_2023366608_A1

Resumen de: AU2023366608A1

A bacterial composition for substrate inoculation to improve the fertility of the substrate comprises a predetermined concentration of at least one strain of autotrophic bacteria, wherein the autotrophic bacteria is characterised in having the ability to produce organic compounds in a predetermined substrate; and a predetermined concentration of at least one strain of mineral nutrient producing bacteria selected from a group including diazotrophic bacteria, potassium solubilizing bacteria and phosphate solubilizing bacteria, wherein the bacteria is characterised in having the ability to produce mineral nutrients in such predetermined substrate. The substrate inoculation of the autotrophic bacterial portion of the composition increases the production of metabolizable forms of organic compounds, and inoculation of the mineral nutrient producing bacterial portion of the composition metabolizes the increased organic compounds for an increased production of metabolizable forms of mineral nutrients in the predetermined substrate.

BACTERIOPHAGE HAVING BACTERIOLYSIS ACTIVITY ON XANTHOMONAS SPP

NºPublicación:  US2025129129A1 24/04/2025
Solicitante: 
KANEKA CORP [JP]
RAKUNO GAKUEN UNIV [JP]
MITSUI & CO LTD [JP]
KANEKA CORPORATION,
RAKUNO GAKUEN UNIVERSITY,
MITSUI & CO., LTD
US_2025089725_PA

Resumen de: US2025129129A1

To control plant diseases caused by Xanthomonas spp., a novel bacteriophage exhibiting bacteriolysis activity specifically on Xanthomonas spp. was isolated. Thus, developed and provided is a plant disease control composition containing the bacteriophage as an active ingredient. Provided are a bacteriolytic agent containing a bacteriophage that has a novel genomic DNA sequence and exhibits bacteriolysis activity specifically on Xanthomonas spp., and a plant disease control composition containing the same as an active ingredient.

METHOD FOR PREVENTING INSECT DAMAGE TO PLANTS

NºPublicación:  US2025127166A1 24/04/2025
Solicitante: 
AJINOMOTO CO INC [JP]
NATIONAL UNIV CORPORATION SAITAMA UNIV [JP]
AJINOMOTO CO., INC,
NATIONAL UNIVERSITY CORPORATION SAITAMA UNIVERSITY
CN_119546186_A

Resumen de: US2025127166A1

A technique useful in the field of agri-horticulture such as a technique for preventing pest damage to plants is provided. Pest damage to plants is prevented by using various glutamic acid derivatives.

INSECT NEUROPEPTIDES 3

NºPublicación:  US2025127177A1 24/04/2025
Solicitante: 
SOLASTA BIO LTD [GB]
Solasta Bio Limited

Resumen de: US2025127177A1

The present invention relates to natural or natural-like analogues of insect pyrokinin neuropeptide Hy-NADEDQQQSVDFTPRL-NH2 (SEQ ID NO:2) having activity against insects, for example hemipteran, dipteran, lepidopteran, blattodean and/or coleopteran insects, such as aphids, moths and fruit flies, and their use as insect control agents (e.g. insecticides) and plant protection agents.

PARTICLES COMPRISING DOUBLE STRANDED RNA AND USE OF SAME IN AGRICULTURE

NºPublicación:  US2025127180A1 24/04/2025
Solicitante: 
YEDA RES AND DEVELOPMENT CO LTD [IL]
THE STATE OF ISRAEL MINI OF AGRICULTURE & RURAL DEVELOPMENT AGRICULTURAL R [IL]
HARVESTR TECH LTD [IL]
YEDA RESEARCH AND DEVELOPMENT CO. LTD,
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL R,
HARVESTR TECHNOLOGIES LTD
AU_2023289032_PA

Resumen de: US2025127180A1

The present invention is directed to an anti-fungal composition including a plurality of particles including: at least one dsRNA molecule including a nucleic acid sequence complementary to at least one transcript of at least one essential gene of a fungus, and methods of using same.

INSECT NEUROPEPTIDES 9

NºPublicación:  US2025127179A1 24/04/2025
Solicitante: 
SOLASTA BIO LTD [GB]
Solasta Bio Limited

Resumen de: US2025127179A1

The present invention relates to natural or natural-like analogues of insect pyrokinin neuropeptides and AKH neuropeptides, and combinations thereof, having activity against insects, for example hemipteran, dipteran, lepidopteran, blattodean and/or coleopteran insects, such as aphids, moths and fruit flies, and their use as insect control agents (e.g. insecticides) and plant protection agents.

BIO-FUNGICIDES FORMULATIONS FOR INHIBITING PHYTOPHTHORA INFESTANS AND METHOD THEREOF

NºPublicación:  US2025127176A1 24/04/2025
Solicitante: 
COROMANDEL INTERNATIONAL LTD [IN]
TAMIL NADU AGRICULTURAL UNIV [IN]
COROMANDEL INTERNATIONAL LIMITED,
TAMIL NADU AGRICULTURAL UNIVERSITY
WO_2023053146_PA

Resumen de: US2025127176A1

The present invention relates to bio-fungicides that inhibits Phytophthora infestans. More particularly, the present invention relates to novel strains of Bacillus spp. that can inhibit Phytophthora infestans. The present invention also relates to bio-fungicidal formulations comprising novel strains of Bacillus spp. either alone or a mixture of novel strains of Bacillus spp., in combination with other excipients.

BACTERIAL STRAIN CAPABLE OF OXIDIZING ELEMENTAL SULPHUR AND USE THEREOF FOR STIMULATING PLANT GROWTH

NºPublicación:  WO2025083314A1 24/04/2025
Solicitante: 
AZUFRERA Y FERTILIZANTES PALLARES S A U [ES]
AZUFRERA Y FERTILIZANTES PALLARES S.A.U
WO_2025083314_PA

Resumen de: WO2025083314A1

The present invention provides a new bacterial strain of the genus Variovorax capable of oxidising elemental sulphur, generating sulphate. When added to a soil, the bacterium can transform the elemental sulphur present into sulphate, the main soluble form of sulphur that can be absorbed by roots, providing plants with more sulphur available for their metabolic needs, stimulating their growth, and the yield of their crops. The use of the bacterium is proposed, optionally with added elemental sulphur, to stimulate plant growth and/or to act as a biostimulant for plants, as well as to modify or restore soils, especially alkaline, limestone, or saline soils, since the activity of the bacterium generates a reduction in pH, enrichment with sulphates, structural modifications, an increase in porosity, solubilisation of phosphorus salts, and other modifications.

INSECT NEUROPEPTIDES 4

NºPublicación:  US2025127178A1 24/04/2025
Solicitante: 
SOLASTA BIO LTD [GB]
Solasta Bio Limited

Resumen de: US2025127178A1

The present invention relates to natural or natural-like analogues of insect pyrokinin neuropeptide Hy-GGSMTFSPRL-NH2(SEQ ID NO:2) having activity against insects, for example hemipteran, dipteran, lepidopteran, blattodean and/or coleopteran insects, such as aphids, moths and fruit flies, and their use as insect control agents (e.g. insecticides) and plant protection agents.

NOVEL METHOD FOR PROMOTING NODULATION IN PLANTS

NºPublicación:  US2025127136A1 24/04/2025
Solicitante: 
UNIV TOULOUSE III PAUL SABATIER [FR]
CENTRE NATIONAL DE LA RECHERCHE SCIENT [FR]
UNIVERSITE TOULOUSE III-PAUL SABATIER,
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
BR_122023021437_PA

Resumen de: US2025127136A1

Micropeptides (miPEPs), or peptides coded by microRNAs, for promoting nodulation between a plant and a bacterium, as well as their use in this manner.

COMPOSITION AND METHOD FOR COATING SEEDS

NºPublicación:  EP4541170A1 23/04/2025
Solicitante: 
CO2 REVOLUTION S L [ES]
CO2 Revolution, S.L
EP_4541170_A1

Resumen de: EP4541170A1

The present invention is comprised in the field of agrobiotechnology. Specifically, the invention relates to a composition and a method for coating seeds which improves the germination thereof. The present invention also relates to a seed coated with the composition of the invention and to the use of said composition for coating seeds. The composition herein described consists of mycorrhizal fungi, bacteria of the genus Pseudomonas, a fungus of the genus Trichoderma, a water retainer, clay, an adherent, a fauna deterrent, and organic matter.

PARTICLES COMPRISING DOUBLE STRANDED RNA AND USE OF SAME IN AGRICULTURE

NºPublicación:  EP4539670A1 23/04/2025
Solicitante: 
YEDA RES & DEV [IL]
THE STATE OF ISRAEL MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT AGRICULTURAL RES ORGANIZATION ARO VO [IL]
Yeda Research and Development Co. Ltd,
The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Institute)
AU_2023289032_PA

Resumen de: AU2023289032A1

The present invention is directed to an anti-fungal composition including a plurality of particles including: at least one dsRNA molecule including a nucleic acid sequence complementary to at least one transcript of at least one essential gene of a fungus, and methods of using same.

STREPTOMYCES VENEZUELAE FOR THE BIOLOGICAL CONTROL OF PLANT DISEASES

NºPublicación:  EP4539669A1 23/04/2025
Solicitante: 
UNIV DEGLI STUDI DI MODENA E REGGIO EMILIA [IT]
CORA SEEDS S R L [IT]
Universit\u00E0 degli Studi di Modena e Reggio Emilia,
Cora Seeds S.r.l
CN_119546189_A

Resumen de: WO2023242812A1

The present invention relates to the use of at least one Streptomyces venezuelae strain, in particular the Streptomyces venezuelae DSM 33887 strain, as a phytopharmaceutical drug, in particular as a fungicide or bio-fungicide. A further object of the invention is a Streptomyces venezuelae strain referred to as DSM 33887, and compositions and uses thereof. The present invention relates to a method for the control of phytopathogens and a method to prevent, control, and treat plant diseases caused by phytopathogens, comprising the use of a Streptomyces venezuelae strain, preferably the DSM 33887 strain.

AGENT FOR INDUCING PLANT DISEASE RESISTANCE, METHOD FOR INDUCING PLANT DISEASE RESISTANCE, AND METHOD FOR PRODUCING AGENT FOR INDUCING PLANT DISEASE RESISTANCE

NºPublicación:  EP4541190A1 23/04/2025
Solicitante: 
PANASONIC IP MAN CO LTD [JP]
Panasonic Intellectual Property Management Co., Ltd
EP_4541190_PA

Resumen de: EP4541190A1

The present disclosure provides a plant disease resistance inducing agent that can effectively induce resistance to a plant disease. A plant disease resistance inducing agent according to the present disclosure contains a secretion product of a cyanobacterium.

MARINE STREPTOMYCES AS NATURAL ANTIFUNGAL AGENTS TO COMBAT THE CHESTNUT BROWN ROT FUNGUS GNOMONIOPSIS SMITHOGILVYI

NºPublicación:  EP4541191A1 23/04/2025
Solicitante: 
CIIMAR CENTRO INTERDISCIPLINAR DE INVESTIG MARINHA E AMBIENTAL [PT]
UNIV DE TRAS OS MONTES E ALTO DOURO [PT]
INST POLITECNICO DE BRAGANCA [PT]
ARDITI AGENCIA REGIONAL PARA O DESENVOLVIMENTO DA INVESTIG TECNOLOGIA E INOVACAO ASSOCIACAO / MARE [PT]
CIIMAR - Centro Interdisciplinar de Investiga\u00E7\u00E3o Marinha e Ambiental,
Universidade de Tr\u00E1s-os-Montes e Alto Douro,
Instituto Polit\u00E9cnico De Bragan\u00E7a,
ARDITI - Ag\u00EAncia Regional para o Desenvolvimento da Investiga\u00E7\u00E3o, Tecnologia e Inova\u00E7\u00E3o - Associa\u00E7\u00E3o / Mare
EP_4541191_A1

Resumen de: EP4541191A1

This disclosure concerns Streptomyces spp. strains, isolated from different marine biotopes, able to inhibit the growth of Gnomoniopsis smithogilvyi (syn. Gnomoniopsis castaneae) (Gs). This fungus is the causal agent of chestnut brown rot responsible for damages in post-harvest fruits, and of wood cankers in the chestnut tree, and is responsible for massive losses in the chestnut sector. The actinobacterial extracts, as well as the corresponding strains, presented an excellent activity against Gs. These strains can be used in integrated and organic agriculture for biological control and integrated Gs management. This ability is of utmost importance in the context of the banning of several fungicidal substances.

COMPOSITIONS AND METHODS FOR CONTROLLING ARTHROPOD PARASITE AND PEST INFESTATIONS

NºPublicación:  EP4541356A2 23/04/2025
Solicitante: 
GREENLIGHT BIOSCIENCES INC [US]
US AGRICULTURE [US]
Greenlight Biosciences, Inc,
The United States of America, as represented by the Secretary of Agriculture
EP_4541356_PA

Resumen de: EP4541356A2

This application provides and discloses anti-parasitic, anti-pest or insecticidal nucleic acid molecules and their calmodulin target genes for the control of arthropod parasites and pests. This application further provides methods and compositions for the control and treatment of parasites and pests in Apis mellifera (honey bee) hives.

付随する炎症のない細菌バイオフィルムの破壊のための組成物および方法

NºPublicación:  JP2025065351A 17/04/2025
Solicitante: 
リサーチインスティチュートアットネイションワイドチルドレンズホスピタル
JP_2025065351_A

Resumen de: US2021139551A1

Methods of breaking down a biofilm or inhibiting, preventing or treating a microbial infection that produces a biofilm are disclosed, which involves administration of a polypeptide that has one or more modified HMG-box 1 domains to a subject suffering from the infection or having the biofilm. By competing with microbial proteins that bind to DNA scaffold in the biofilm, these polypeptides destabilize the biofilm leading to destruction and removal of the biofilm by the immune system.

MICROALGAE STRAIN HAVING EFFECT OF PROMOTING PLANT GROWTH AND USE THEREOF

NºPublicación:  US2025122464A1 17/04/2025
Solicitante: 
CJ CHEILJEDANG CORP [KR]
CJ CheilJedang Corporation
US_2025122464_PA

Resumen de: US2025122464A1

The present application relates to a novel microalgae strain with the efficacy of promoting plant growth and a use thereof. When cultured in the presence of fermentation exhaust gas, a novel Chlorella vulgaris CD02-3002 strain according to an aspect grows fast with a high efficiency of photosynthesis and thus can effectively reduce the exhaust gas generated by microbial fermentation. Having the effect of promoting plant growth when applied to plants, a culture of the strain or a supernatant of the culture can be used as a fertilizer for plants and thus can be advantageously applied as a novel carbon reduction technique.

SYSTEM AND METHOD FOR RELEASING A BIOLOGICAL AGENT SUCH AS PREDATORY MITES IN PROXIMITY OF VEGETATION

NºPublicación:  WO2025076620A1 17/04/2025
Solicitante: 
ANATIS BIOPROTECTION INC [CA]
ANATIS BIOPROTECTION INC
WO_2025076620_PA

Resumen de: WO2025076620A1

A biological agent releasing receptacle for releasing a biological agent in proximity of vegetation to be treated is provided. The biological agent releasing receptacle includes an elongated body with a receptacle wall defining a receptacle cavity configured to receive the biological agent therein. The elongated body includes a soil-contacting portion configured to be inserted into soil and a biological agent releasing portion located opposite the soil-contacting portion and configured to extend outwardly from the soil, away from the soil-contacting portion. One or more biological agent releasing opening is defined in the receptacle wall of the biological agent releasing portion to release the biological agent received in the receptacle cavity in proximity of the vegetation to be treated. Methods for preparing the biological agent releasing receptacle, as well as methods for installing the biological agent releasing receptacle, for instance in a crop, are also provided.

BACTERIOPHAGE COCKTAIL TO TARGET DIVERSE LINEAGES OF MULTIDRUG-RESISTANT KLEBSIELLA PNEUMONIAE

NºPublicación:  WO2025081186A1 17/04/2025
Solicitante: 
THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE DIRECTOR OF THE DEFENSE HEALTH AGENCY [US]
THE US GOV AS REPRESENTED BY THE SECRETARY OF THE ARMY [US]
THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE DIRECTOR OF THE DEFENSE HEALTH AGENCY,
THE UNITED STATES GOVERNMENT, AS REPRESENTED BY THE SECRETARY OF THE ARMY
WO_2025081186_A1

Resumen de: WO2025081186A1

Herein, Klebsiella pneumoniae phage cocktails comprising a lytic phage EKq1 newly isolated on Klebsiella quasipneumoniae are introduced. A 5 -phage cocktail KPM1 comprises five K pneumoniae phages including EKq1, EKq2, AFR4, KEN39, KEN42, and the efficacy of KPM1 phage cocktail is demonstrated in carbapenem-resistant K pneumoniae strain-infected mice model. Also, a 6-phage cocktail KPM1-1 is introduced, which further comprises EKp148 in addition to the five core KPM1 phages. The cocktails can be used as main ingredients of pharmaceutical compositions either alone or in combination with antibiotics. Also, methods of using the same for the treatment of respiratory infections caused by K pneumoniae are presented.

METHODS FOR MITIGATING THE EFFECTS OF DISEASE IN PLANTS

NºPublicación:  WO2025080749A1 17/04/2025
Solicitante: 
BENBARRA LLC [US]
BENBARRA LLC
WO_2025080749_A1

Resumen de: WO2025080749A1

Methods are provided for treating a pathogen infection or reducing the risk of developing a pathogen infection, reducing the severity and/or incidence of a pathogen infection of a plant or part thereof, and improving the growth and/or development of a pathogen-infected plant or part thereof comprising contacting the plant with an effective amount of a TOR (Target of Rapamycin) inhibitor.

CONDENSED RING COMPOUND, AND HARMFUL ARTHROPOD-CONTROLLING COMPOSITION CONTAINING SAME

Nº publicación: WO2025079634A1 17/04/2025

Solicitante:

SUMITOMO CHEMICAL COMPANY LTD [JP]
\u4F4F\u53CB\u5316\u5B66\u682A\u5F0F\u4F1A\u793E

WO_2025079634_PA

Resumen de: WO2025079634A1

Provided is a compound having an excellent controlling effect against harmful arthropods. A compound represented by formula (I) wherein L represents a single bond, or the like; R1 represents a C1-C6 linear hydrocarbon group, or the like; R2 represents a 5- or 6-membered aromatic heterocyclic group, or the like; X represents NR11C(Z)R12, or the like; Z represents an oxygen atom, or the like; R11 represents a C1-C6 linear hydrocarbon group, or the like; R12 represents a phenyl group that may be substituted by one or more substituents, or the like; and Q represents a group represented by formula A1 (wherein # represents a binding position to 2, and ● represents a binding position to a carbon atom) or an N-oxide thereof has an excellent controlling effect against harmful arthropods.

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