Alerta

Confidence Indications Derived From Plural Strings

Absstract of: US20260341401A1

0000 Disclosed are systems comprising an analyzing unit comprising a) a receiver configured to receive a plurality of sequencing reads from a sample, the plurality of sequencing reads comprising at least one genetic variation undetectable within a sequencing system error rate; b) a noise processing filter configured to: i) reduce signal noise from the plurality of sequencing reads; ii) calculate a confidence indication based on a determination from at least one sequencing read of the plurality of sequencing reads; and iii) calculate a corrected confidence indication based on a comparison of the determinations from at least two sequencing reads, each drawn from the plurality of sequencing reads. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

연속 접힘 시트들에 기초한 스캐폴드들

Absstract of: WO2025117862A1

Provided herein are various embodiments related to the design, creation, and use of a folded sheet scaffold for medical devices. The scaffold comprises a shellular porous pseudorandom orientable architecture composed of a continuous folded sheet of topological genus-n. Methods for designing the scaffold involve driving noise from an infinite 3D noise field to define a field with real space, tuning field values based on user input, and subtracting to create thin wall geometry. The methods can be computer-implemented or executed by a processor following instructions stored on a non-transitory computer-readable medium. A computer system for designing the scaffold includes modules for noise-driving, tuning, and subtracting. The disclosure also includes a folded sheet scaffold formed by these methods and a medical device comprising the folded sheet scaffold.

TIME-BASED WIRELESS PAIRING BETWEEN A MEDICAL DEVICE AND A WALL UNIT

Absstract of: EP4832004A2

0001 A system for use in a healthcare facility having a patient room. The system comprises a patient bed having bed circuitry including a first wireless transceiver and an AC power cord, and a wall module including a housing configured to be mounted at a fixed location in the patient room of the healthcare facility. The housing carries an AC receptacle and has a front wall that is formed to include a first recess in which the AC receptacle is accessible. The wall module further includes module circuitry carried by the housing. The module circuitry includes a second wireless transceiver and an AC plug sensor that forms an optical beam in the recess in front of the AC receptacle. In response to the optical beam being interrupted by a plug of the AC power cord being plugged into the AC receptacle, the second wireless transceiver communicates with the first wireless transceiver to implement a time-based wireless pairing operation between the wall module and the patient bed.

Reconstruction of a three-dimensional image of a patient

Absstract of: GB2705798A

A method 100 for reconstruction of 3D image of a patient is disclosed. The method comprises obtaining a projection set comprising a plurality of 2D CBCT projections of a first volume of the patient 110, and obtaining a 3D image of a second volume of the patient, wherein the second volume of the patient at least partially overlaps with the first volume of the patient 120. The method further comprises using acquisition information relating to the obtained projection set to generate, from the 3D image, synthetic projections of the second volume of the patient 130, and extending the projections of the first volume of the patient from the obtained projection set with information from the synthetic projections of the second volume of the patient 140. The method further comprises using the extended projections to generate a 3D image of a third volume of the patient, the third volume comprising a combination of the first and second volumes. (Figure 1)

RADICALLY POLYMERISABLE COMPOUND AND COMPOSITION

Absstract of: WO2025131708A1

The invention relates to a radically polymerisable compound represented by a structure of formula 1: PG1-Sp1-OC(O)NH-K-NHC(O)O-Arn-OC(O)NH-K-NHC(O)O-Sp2-PG2 ( formula 1), and to a radically polymerisable composition, to the use of the radically polymerisable compound or the radically polymerisable composition for producing a polymerisable dental material and to a cured dental material.

STAIN RESISTANT COMPOSITIONS AND METHODS FOR PREPARING THE SAME

Absstract of: WO2025137128A1

The present disclosure provides polymerizable composition that can produce desirable stain resistant polymeric materials, polymer compositions, and/or photo-curable resins. Further provided herein are methods of producing polymerizable compositions, resins, devices, and polymeric materials. Also provided herein are methods of using polymerizable compositions, resins, and polymeric materials for the fabrication (e.g., via 3D printing) of medical devices, such as orthodontic appliances.

Component mixing in 3D bioprinting

Absstract of: GB2705670A

Apparatus 100 suitable for supplying a 3D printer 10, particularly a bioprinter, with a print material, for example bioinks, having a predefined ratio of components, the apparatus comprising plural component reservoirs 130A-C, for example vials, each reservoir holding a material to be printed and being in common fluid communication with a printing nozzle 114, one or more devices 124A-C for generating a pressure in each of the reservoirs for a selectable time period for dispensing a volume of the respective component out of the respective reservoir to the nozzle supply, and thereby to define a ratio of components. A controller 150 for controlling the or each device may be provided, UV light may be applied to the material and the ratio selected influences the intensity of UV the light applied. A method for mixing components of a 3D printable material to a predefined ratio is also provided. Figure 1.

IMPRESSION TRAY WITH LATTICE STRUCTURE

Absstract of: EP4830663A1

Die Erfindung betrifft einen Abformlöffel zur Anfertigung von Gebissabdrücken mithilfe von Abformmaterial, ein Verfahren zur Herstellung sowie ein nichtflüchtiges Speichermedium , wobei der Abformlöffel umfasst: einen Löffelabschnitt, ausgestaltet zur Aufnahme des Abformmaterials, und einen Halteabschnitt, umfassend einen Haltegriff, wobei der Löffelabschnitt ferner zur Aufnahme eines Gebisses eines Ober- oder Unterkiefers ausgestaltet ist, dadurch gekennzeichnet, dass eine Oberfläche des Abformlöffels zumindest in Teilen des Löffelabschnitts eine Gitterstruktur aufweist, die zur Aufnahme des Abformmaterials ausgestaltet ist.

PMMA DLP Compositions for DLP printing that contain PMMA

Absstract of: KR20260155905A

본 발명은 기계적 강도와 UV 저항성이 향상된 PMMA를 포함하는 DLP(Digital Light Processing) 인쇄용 조성물 및 이를 이용하여 제조된 마이크로니들 패치에 관한 것이다.

DIGITAL METHOD FOR MANUFACTURING A DENTAL COMPONENT

Absstract of: US2020222151A1

A system for dental implant restoration is provided. It includes universal aligning adaptors and prosthetic components having co-operable indices, which together form a translational, integrating system which aligns, synchronizes, and references the prosthetic components about an implant's central axis of rotation. Rotation of an adaptor about a prosthetic component, with its reference point becoming aligned to a predetermined reference point on the prosthetic component, followed by the rotation of the adaptor/prosthetic component assembly about the implant, situates the prosthetic component in a predetermined position such that all other prosthetic components become synchronized to the adaptor's reference point. The prosthetic component is mechanical for clinical or lab bench use, or is virtual for restoration design in a software program, prior to milling prosthetic abutments or devices. Abutments, healing caps and screw access holes are realigned to preferred positions and synchronized with minimal deviation from the ideal direction.

CELL ENCAPSULATION DEVICES AND METHODS OF USING SAME

Absstract of: WO2022061007A1

Disclosed herein are devices for encapsulating biological cells and are suitable to be implanted into a subject. In different aspects of the disclosure, the devices may comprise a plurality of polymer layers. In one aspect, a device comprises a first polymer layer and a second polymer layer. In some cases, the first polymer layer may be a nanoporous polymer layer. In some cases, the second polymer layer may be a macroporous polymer layer. The first and second polymer layers may define a lumen for enclosing a population of cells. In some cases, the device further comprises a third polymer layer. The devices may be used to transplant cells producing therapeutic agents into a subject (e.g., for the treatment of a disease).

INTELLIGENT PUNCTURE NAVIGATION SYSTEM AND METHOD

Absstract of: EP4830656A1

0001 Provided is an intelligent puncture navigation system and method. The system comprises a medical imaging device (1), an upper computer (2), a positioning device (3), and an intelligent puncture needle (4). The medical imaging device (1) is configured to acquire a three-dimensional scanning image of tissues to be punctured; the upper computer (2) is configured to determine puncture information according to the three-dimensional scanning image; the positioning device (3) is configured to form a mark on the skin surface of the area to be punctured according to the puncture information; the intelligent puncture needle (4) is configured to perform puncturing according to the mark and the puncture information and acquire real-time angle information of the puncture needle; the upper computer (2) is further configured to monitor the intelligent puncture needle (4) according to the real-time angle information. The intelligent puncture navigation system and method can achieve the navigation function without image registration, thereby avoiding puncture deviation or failure caused by image registration errors. The system and method offer flexible use and improve the puncture efficiency and accuracy.

SCAFFOLD BASED IMPLANTS

Absstract of: EP4830666A2

0001 Certain aspects of the present disclosure provide a flexible scaffold implant comprising a plurality of layered structures, the plurality of layered structures comprising: a first layered structure having a three-dimensional (3D) shape and formed from a bioresorbable material, and a second layered structure conforming to the corresponding 3D shape of the first layered structure and formed from the bioresorbable material. The first layered structure is arranged in proximity to the second layered structure. The first layered structure is configured to dissolve for resorption at a different rate than the second layered structure based on design elements of the first layered structure and the second layered structure. The plurality of layered structures are flexible.

HIS-PURKINJE SYSTEM CAPTURE DETECTION

Absstract of: EP4832013A2

0001 A medical device is configured to receive a cardiac signal and determine a morphology matching score from the cardiac signal and a capture detection morphology template that corresponds to a first type of cardiac pacing capture that includes capture of at least a first portion of the His-Purkinje system. The device is configured to detect a second type of cardiac pacing capture in response to the morphology matching score being less than the first match threshold. The second type of cardiac pacing capture is different than the first type of cardiac pacing capture and may include capture of the ventricular myocardium and/or a second portion of the His-Purkinje system different than the first portion.

SAFE AND EFFECTIVE METHOD OF TREATING PSORIATIC ARTHRITIS WITH ANTI-IL23 SPECIFIC ANTIBODY

Absstract of: EP4830728A2

A method of treating psoriatic arthritis in a patient by administering an IL-23 specific antibody, e.g., guselkumab, in a clinically proven safe and clinically proven effective amount and the patient achieves significant ACR20/50/70, PASI70/90/100, MDA, HAQ-DI, SF-36 PCS, MCS, LEI/dactylitis, PASDAS, GRACE, mCPDAI, DAPSA or RAPID3 improvement as measured 16, 24, 32, 40 and 48 weeks after initial treatment.

一時的なタトゥーのためのインクジェット印刷プロセス

Absstract of: US20250108658A1

0000 Provided are temporary tattoos comprising cosmetic inkjet ink and methods of making thereof. The method of making the temporary tattoo may comprise printing, using an inkjet printer, an image made from a cosmetic inkjet ink on a side of a transfer film that comprises an inkjet receptive coating. The image printed on the transfer film may be dried to allow the image to absorb into the coating. Once dried, an adhesive may be applied to the side of the transfer film comprising the inkjet receptive coating to cover the image. Thus, the temporary tattoo may comprise a transfer film comprising an inkjet receptive coating, and an adhesive film.

COMPUTER-IMPLEMENTED METHOD AND CAD SYSTEM FOR AUTOMATICALLY CENTERING AND ALIGNING A 3D MESH SCAN OF A SINGLE JAW IN A CAD SYSTEM

Absstract of: EP4553764A1

The subject application provides a computer-implemented method (100) and CAD system (200) for automatically centering and aligning a 3D mesh scan (10) of a jaw in a CAD system.The inventors propose to automatically center and align a 3D mesh scan (10) of a jaw in a CAD system, wherein the initial orientation of the 3D mesh scan (10) is arbitrary.

放射線被ばくを低減するための医用撮像システム

Absstract of: MX2026002915A

Methods, systems, and apparatuses are described herein for using processes and machine learning techniques to optimize medical imaging processes to reduce inadvertent exposure to harmful radiation. A machine learning model may be trained to output recommended medical imaging device operating parameter settings. Available operating parameters of a medical imaging device may be determined, and patient data may be received. The patient data and the available operating parameters may be used as input to the trained machine learning model, which might output recommended operating parameter settings. In turn, this output in addition to other calculations might be used to transmit, to the medical imaging device, data that causes modification of the operating parameters of the medical imaging device. Metadata corresponding to one or more images captured by the medical imaging device may be received, and the trained machine learning model might be further trained based on that metadata.

一种内窥镜三信号一体化隔离传输系统

Absstract of: CN122994457A

本发明公开了一种内窥镜三信号一体化隔离传输系统，包括主机信号集成单元、隔离耦合单元、手柄总线和手柄信号分离单元；主机信号集成单元将控制信号嵌入图像数据流形成串行融合数据流，隔离耦合单元对串行融合数据流和直流电源分别进行电气隔离后，通过融合网络将两者耦合至同一组差分线对构成的手柄总线，手柄信号分离单元从手柄总线上分离出电源和信号并恢复控制信号与图像数据。由此将电源、数据和控制三类信号融合于一组差分线传输，减少线芯数量，在满足电气隔离要求下改善线缆柔细度与操作手感。

基于虚拟现实和眼动追踪的谵妄筛查和干预系统

Absstract of: CN122973021A

0001 本发明提供一种基于虚拟现实和眼动追踪的谵妄筛查和干预系统，结合沉浸式VR交互终端、头部姿态补偿的双目眼动采集技术、多维度谵妄特异性测试任务、多子模型融合的分级筛查算法、转化风险预测模型，实现ICU谵妄的非侵入式、客观化、精准化早期筛查与风险预警，同时配套个性化VR干预方案，形成全流程闭环管理，彻底解决现有临床谵妄评估的主观依赖性强、ICU场景适配性差、早期预警能力不足的核心问题。

低算力穿戴设备的离线式身体精力评分方法及系统

Absstract of: CN122991624A

本发明涉及可穿戴设备技术领域，更具体地，涉及低算力穿戴设备的离线式身体精力评分方法及系统。该方案包括以每日凌晨4:00为固定结算时刻，采集前日00:00至当日03:59的生理数据作为原始输入数据集；基于睡眠参数计算分项求和并扣减清醒时长扣分，钳位得睡眠得分；按累计有效晨起天数N分级调用固定基线、全量平均或30天滑动平均生成HRV与静息心率个人基线，映射输出对应得分；按前一日中高强度心率累计分钟数查表得运动得分；五项得分按0.4、0.3、0.15、0.1、0.05加权求和后，串行执行熬夜扣减与生理期缩放修正，取整钳位输出0~100分评分与五档状态等级，全程单次结算，功耗低，适于低算力设备。

一种表面肌电信号识别方法、模型训练方法及系统

Absstract of: CN122986342A

0001 本发明提供一种表面肌电信号识别方法、模型训练方法及系统，该方法包括：通过包含多个二维时频谱图的训练样本集对初始表面肌电信号识别模型进行训练，局部调整提取模块进行局部时频特征提取并通过特征序列重构模块转换和空间位置编码模块叠加空间偏置，输入时空上下文建模模块输出全局时空融合特征序列，最终通过多任务并行输出模块输出动作类别预测值、关节状态预测值和肌肉疲劳指数预测值，与标签的偏差构建融合损失函数对初始表面肌电信号识别模型进行参数更新获得表面肌电信号识别模型；能够实现表面肌电信号识别的稳定性和准确性并实时反馈肌肉状态。

一种PICC穿刺智能导引装置及使用方法

Absstract of: CN122973101A

本发明公开了一种PICC穿刺智能导引装置及使用方法，属于医疗器械领域。该装置为可拆卸外挂附件，装配于超声探头，用于PICC改良Seldinger穿刺。装置通过血管深度自动测量模块自动采集皮肤至靶血管垂直深度H，并采集五项患者个体化特征参数，微控制器依据θ0=arctan(H/D)计算基准角度，并通过预训练的AI修正模型修正后，再经临床安全区间限幅输出目标穿刺角度，供操作人员手动调节或自动驱动导针座摆角锁止。当基准角度超出临床安全区间时，装置执行钳位输出并给出提示。本发明实现自动测深‑几何模型基准运算‑AI个体化修正‑双重角度钳位‑角度输出的完整智能闭环，相比纯几何基准角度方案，提高了穿刺成功率。

手指外骨骼阻抗辨识与牵伸力度闭环控制方法及系统

Absstract of: CN122973234A

本发明公开手指外骨骼阻抗辨识与牵伸力度闭环控制方法及系统，属于生理参数测量与分析技术领域，用于手指外骨骼阻抗辨识与牵伸力度闭环控制，包括步采集电机电流、多通道肌电和温度信号并预处理，获得关节角度与净阻抗力矩，基于肌电归一化计算主动收缩指数并筛选有效样本，扣除神经性力矩得到机械性挛缩阻抗力矩；构建三参数模型辨识关节刚度及弹性区终点，引入温度与瘢痕因子修正安全上限；依据接近度变量实现力位混合控制，保持期辨识松弛参数并允许角度递增，三级熔断分级响应，记录每日牵伸剂量与最大角度并同步至治疗师端。本发明通过多模态生理信号融合辨识关节阻抗特性，实现个性化安全牵伸调控，提高评估准确性与治疗有效性。

基于操作日志的作业人员疲劳状态评估方法及终端设备

Nº publicación: CN122991607A 27/10/2026

Applicant:

青岛中科英泰商用系统股份有限公司

Absstract of: CN122991607A

0001 本发明公开一种基于操作日志的作业人员疲劳状态评估方法及终端设备。本方法获取交易处理时长与商品总难度系数计算实际单位难度耗时，经标准耗时模型得到预测单位难度耗时，二者差值生成耗时残差；采集连续残差构建残差序列，提取残差均值、残差变异系数、正残差占比、残差偏度；对特征归一化后加权融合得到综合疲劳系数，依据分级阈值判定疲劳等级。所述终端设备包括存储器、处理器，处理器运行程序可实现上述评估方法。本方案使用收银终端原生交易日志，无需额外采集硬件，消除客流量、商品复杂度的业务负载干扰，依靠多维度特征量化疲劳，规避硬件成本、隐私泄露问题，减少业务波动造成的评估误判，实现无侵入、高精度的作业人员疲劳实时评估。