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Solicitudes publicadas en los últimos 60 días (excluida automoción) / Applications published in the last 60 days (Automotion publications excluded)
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NANOPARTICLE-FUNCTIONALIZED ELECTROSPUN SCAFFOLDS AND USES THEREOF

Publication No.:  US20260325720A1 22/10/2026
Applicant: 
THE TRUSTEES OF COLUMBIA UNIV IN THE CITY OF NEW YORK [US]
The Trustees of Columbia University in the City of New York
US_20260325720_A1

Absstract of: US20260325720A1

0000 Compositions and methods of making of piezoelectric polymer scaffolds and a plurality of charged nanoparticles and methods of use thereof.

SYSTEMS AND METHODS FOR DETECTING THE RISK, PRESENCE, OR ABSENCE OF CARDIOTOXICITY IN A SUBJECT

Publication No.:  WO2026222281A1 22/10/2026
Applicant: 
SKRIBE MEDICAL INC [US]
SKRIBE MEDICAL, INC.
WO_2026222281_A1

Absstract of: WO2026222281A1

An exemplary system for detecting the presence, absence, or risk of cardiotoxicity in a subject can include one or more sensors, a hub device, a cardiotoxicity detection system, and a notification system. The one or more sensors may be worn on the subject's body and can sense one or more physiological parameter signals related to cardiovascular health. The hub device can wirelessly receive the one or more physiological parameter signals from the one or more sensors and transmit the physiological parameter signals to the cardiotoxicity detection system. The hub device and the one or more sensors may communicate through resonant body communication. The cardiotoxicity detection system can determine a cardiotoxicity score based on the physiological parameter signals using a cardiotoxicity machine learning model trained to determine a cardiotoxicity score based on the one or more physiological parameter signals.

METHOD AND APPARATUS FOR PROVIDING A RADIATION TREATMENT PLAN

Publication No.:  US20260325873A1 22/10/2026
Applicant: 
SIEMENS HEALTHINEERS INT AG [CH]
Siemens Healthineers International AG
US_20260325873_A1

Absstract of: US20260325873A1

0000 A control circuit accesses information regarding a time-based physiological limit for the particular patient and uses that time-based physiological limit as an optimization objective. The control circuit can then automatically split a treatment trajectory for the radiation treatment plan as a function of that time-based physiological limit.

RADIATION TREATMENT PLAN OPTIMIZATION METHOD AND APPARATUS

Publication No.:  US20260325875A1 22/10/2026
Applicant: 
SIEMENS HEALTHINEERS INT AG [CH]
Siemens Healthineers International AG
US_20260325875_A1

Absstract of: US20260325875A1

0000 A control circuit accesses patient geometry information that includes at least one target volume along with radiation treatment apparatus geometry information for a particular radiation treatment apparatus and radiation direction field geometry setup parameters that include at least one field geometry setup with at least one gantry angle, one couch angle, and one isocenter position. The control circuit can then automatically determine multi-leaf collimator (MLC) plane field geometry setup parameters for at least one radiation direction field geometry setup using a single automated multiple-field setup per radiation direction field followed by optimizing the radiation treatment plan as a function of the MLC plane field geometry setup parameters to provide an optimized radiation treatment plan.

RADIATION TREATMENT PLAN OPTIMIZATION METHOD AND APPARATUS

Publication No.:  US20260325874A1 22/10/2026
Applicant: 
SIEMENS HEALTHINEERS INT AG [CH]
Siemens Healthineers International AG
US_20260325874_A1

Absstract of: US20260325874A1

To facilitate optimizing a radiation treatment plan for a particular patient using a particular radiation treatment apparatus, by one approach, a control circuit iteratively accesses a fluence space optimization solution for a radiation treatment plan for the particular patient, generates control point parameters for the particular radiation treatment apparatus as a function of the fluence space optimization solution, determines a treatment delivery time using the control point parameters for the particular radiation treatment apparatus, and, when treatment delivery time is suboptimal, modifies the fluence space optimization solution.

SYSTEMS AND METHODS FOR ORGANIZING MEDICATION STORAGE CABINETS

Publication No.:  WO2026222501A1 22/10/2026
Applicant: 
OMNICELL INC [US]
OMNICELL, INC.
WO_2026222501_A1

Absstract of: WO2026222501A1

A system for determining an optimal configuration for a medication storage cabinet, the system comprising: one or more processors; and a memory storing instructions that, when executed by the one or more processors, cause the system to perform operations comprising: collecting cabinet data and medication data, preprocessing the collected data, wherein the preprocessing includes cleaning, normalizing, and transforming the collected data, performing feature engineering on the preprocessed data to generate engineered features, selecting relevant features, performing dimensionality reduction on the preprocessed data, and training a machine learning model using the selected features, wherein the machine learning model includes a random forest model for generating an initial cabinet configuration and a reinforcement learning model for continuous real-time optimization; generating an optimal configuration for the medication storage cabinet based on the trained machine learning model; and receiving real-time updates and incorporating feedback to refine the generated optimal configuration.

PRINTED UNIVERSAL GRADIENT INTERFACES FOR BIOELECTRONIC DEVICES AND METHODS OF MAKING THE SAME

Publication No.:  US20260326367A1 22/10/2026
Applicant: 
UNIV OF NOTRE DAME DU LAC [US]
UNIVERSITY OF NOTRE DAME DU LAC
US_20260326367_A1

Absstract of: US20260326367A1

0000 Described herein is a printed universal gradient interface (UGI) for stretchable and strain-insensitive bioelectronics. The UGI comprises a multi-polymer gradient extending between a first polymer end and a second polymer end with a graded weight ratio from 1:0 to 0:1. The UGI may connect a biological surface to an electrically conductive material, enabling improved strain insensitivity and electrical stability under high stretch ratios. Methods of making the UGI via aerosol jet printing techniques and bioelectronic devices incorporating the UGI with electrically conductive material are also described.

NERVE COAPTATION DEVICE

Publication No.:  WO2026222344A1 22/10/2026
Applicant: 
UNIV CALIFORNIA [US]
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
WO_2026222344_A1

Absstract of: WO2026222344A1

Described herein is a nerve coaptation device. The nerve coaptation device includes a nerve sheath defining an opening and a plurality of burrs or hooks coupled to an inner surface of the nerve sheath. A first portion of the nerve sheath is configured to receive a first nerve through the opening. A second portion of the nerve sheath is configured to receive a second nerve through the opening. The plurality of burrs or hooks are configured to couple to the first nerve and the second nerve.

PROGRAMMABLE DELAYED-RELEASE CONTAINER SYSTEM FOR ORAL DRUG DELIVERY

Publication No.:  US20260325451A1 22/10/2026
Applicant: 
WADI AHMED [US]
MANIRUZZAMAN MOHAMMED [US]
Wadi Ahmed
Maniruzzaman Mohammed
US_20260325451_A1

Absstract of: US20260325451A1

0000 A delayed-release oral dosage form comprising a container structure defining an internal cavity, a swellable composition disposed within the internal cavity, and an active pharmaceutical ingredient. The container structure includes one or more ingress openings configured to permit entry of external fluid into the internal cavity while substantially preventing release of the active pharmaceutical ingredient prior to rupture of the container structure. Upon exposure to fluid, the swellable composition hydrates and expands within the confined cavity, generating internal pressure. The pressure increases until rupture of at least a portion of the container structure occurs, thereby releasing the active pharmaceutical ingredient after a delay period following administration.

ACUSCULTAION SYSTEM APPARATUS FOR PROVIDING HEART SOUND DATA OF ACUSCULTAION SYSTEM

Publication No.:  KR20260153464A 22/10/2026
Applicant: 
SEOUL NATIONAL UNIV HOSPITAL [KR]
CHUNG ANG UNIV INDUSTRY ACADEMIC COOPERATION FOUNDATION [KR]
\uC11C\uC6B8\uB300\uD559\uAD50\uBCD1\uC6D0
\uC911\uC559\uB300\uD559\uAD50 \uC0B0\uD559\uD611\uB825\uB2E8

Absstract of: KR20260153464A

본 발명은 청진 시스템에 관한 것으로, 사용자의 신체에서 발생하는 심음(heart sound)을 집속하는 청진 장치; 및 상기 청진 장치와 인접하게 배치되는 마이크로폰을 포함하며, 상기 마이크로폰을 통해 상기 심음을 획득하고, 기 학습된 인공신경망을 이용하여 상기 심음으로부터 심음 데이터를 제공하는 심음 데이터 제공 장치;를 포함하되, 상기 심음 데이터 제공 장치는 상기 인공신경망을 이용하여 상기 심음 데이터, 가속도계 데이터 및 자이로스코프 데이터를 분류하고, 상기 분류에 의한 결과를 기초로 상기 청진 장치의 심음 청진 위치를 가이드하기 위한 정보를 사용자에게 제공할 수 있다.

METHODS AND SOFTWARE FOR PROVIDING TARGETED ADVERTISING TO A PRODUCT PROGRAM

Publication No.:  US20260331248A1 22/10/2026
Applicant: 
DESPREZ LLC [US]
Desprez, LLC
US_20260331248_A1

Absstract of: US20260331248A1

Methods and software that allow one or more users to utilize targeted-advertising functionality in the context of a product program. For example, such logistical functionality may enable users to benefit from the use of one or more functionalities enabled by targeted advertising, such as fully or partially ad-sponsored software, relevant training or assistance recommendations, and user-customized advertising, among others. Various corresponding and related methods and software are described.

TABLET ULTRASOUND SYSTEM

Publication No.:  US20260325102A1 22/10/2026
Applicant: 
TERATECH CORP [US]
Teratech Corporation
US_20260325102_A1

Absstract of: US20260325102A1

Exemplary embodiments provide systems and methods for portable medical ultrasound imaging. Preferred embodiments utilize a tablet touchscreen display operative to control imaging and display operations without the need for using traditional keyboards or controls. Certain embodiments provide a multi-chip module for an ultrasound engine of a portable medical ultrasound imaging system, in which a transmit/receive chip, an amplifier chip and a beamformer chip are assembled in a vertically stacked configuration. Exemplary embodiments also provide an ultrasound engine circuit board including one or more multi-chip modules, and a portable medical ultrasound imaging system including an ultrasound engine circuit board with one or more multi-chip modules. Exemplary embodiments also provide methods for fabricating and assembling multi-chip modules as taught herein.

SYSTEM AND METHOD FOR TASK-LESS MAPPING OF BRAIN ACTIVITY

Publication No.:  US20260325080A1 22/10/2026
Applicant: 
WASHINGTON UNIV [US]
Washington University
US_20260325080_A1

Absstract of: US20260325080A1

A computing device for use in a system for mapping brain activity of a subject includes a processor. The processor is programmed to select a plurality of measurements of brain activity that is representative of at least one parameter of a brain of the subject during a resting state. Moreover, the processor is programmed to compare at least one data point from each of the measurements with a corresponding data point from a previously acquired data set from at least one other subject. The processor is also programmed to produce at least one map for each of the measurements based on the comparison of the resting state data point and the corresponding previously acquired data point. The processor may also be programmed to categorize the brain activity in a plurality of networks in the brain based on the map.

PHOTODEFINED APERTURE PLATE AND METHOD FOR PRODUCING THE SAME

Publication No.:  ES3082429T3 22/10/2026
Applicant: 
STAMFORD DEVICES LTD
Stamford Devices Limited
US_2020347507_A1

Absstract of: US2020347507A1

In one embodiment, a method for manufacturing an aperture plate includes depositing a releasable seed layer above a substrate, applying a first patterned photolithography mask above the releasable seed layer, the first patterned photolithography mask having a negative pattern to a desired aperture pattern, electroplating a first material above the exposed portions of the releasable seed layer and defined by the first mask, applying a second photolithography mask above the first material, the second photolithography mask having a negative pattern to a first cavity, electroplating a second material above the exposed portions of the first material and defined by the second mask, removing both masks, and etching the releasable seed layer to release the first material and the second material. The first and second material form an aperture plate for use in aerosolizing a liquid. Other aperture plates and methods of producing aperture plates are described according to other embodiments.

Ultrasound System with Target and Medical Instrument Awareness

Publication No.:  US20260325228A1 22/10/2026
Applicant: 
BARD ACCESS SYSTEMS INC [US]
Bard Access Systems, Inc.
US_20260325228_A1

Absstract of: US20260325228A1

A needle insertion system includes a console including a processor and non-transitory, computer-readable medium having stored thereon logic that, when executed by the processor, is configured to initiate a target recognition process and a needle guidance process. The target recognition process can be configured to receive user input indicating a desired target by applying a machine learning model to features of candidate targets in ultrasound-imaging data, wherein the desired target is associated with a highest confidence score. The needle guidance process can be configured for guiding insertion of a needle into the desired target by the machine learning model, wherein the machine learning model determines a proximity of a trajectory of the needle to the desired target based on magnetic information about the needle. The system can also include an ultrasound probe configured to provide to the console first electrical signals corresponding to the ultrasound-imaging data.

SYSTEMS AND METHODS FOR SEGMENTING DENTAL SCANS

Publication No.:  US20260331255A1 22/10/2026
Applicant: 
ALIGN TECH INC [US]
Align Technology, Inc.
US_20260331255_A1

Absstract of: US20260331255A1

0000 Systems and methods for segmenting dental scans. A three-dimensional (3D) scan of a patient's dentition may be automatically segmenting with one or more convolutional neural networks. The segmented 3D scan may be incorporating into a 3D dental model of a virtual treatment plan. The virtual treatment plan may be output.

ADDITIVE MANUFACTURING TECHNIQUES FOR HEAD WEARABLE ORTHOTIC

Publication No.:  US20260325336A1 22/10/2026
Applicant: 
HANGER INC [US]
Hanger, Inc.
US_20260325336_A1

Absstract of: US20260325336A1

A recommendation system for a pediatric orthotic device includes a scan device, a display device, and processing circuitry. The scan device is configured to obtain scan data of a patient's head. The processing circuitry is configured to obtain the scan data of the patient's head. The processing circuitry is configured to determine, based on the scan data, a selection of (i) an outer shell of the pediatric orthotic device from multiple outer shell options, and (ii) one or more pads from multiple pads for placement within the outer shell to provide cranial remodeling therapy. The processing circuitry is configured to operate the display device to notify a clinician regarding the selection of (i) the outer shell, and (ii) the one or more pads.

TRANSFER APPARATUS FOR ORTHODONTIC APPLIANCES AND RELATED METHODS OF MANUFACTURING

Publication No.:  US20260325261A1 22/10/2026
Applicant: 
SOLVENTUM INTELLECTUAL PROPERTIES CO [US]
Solventum Intellectual Properties Company
US_20260325261_A1

Absstract of: US20260325261A1

0000 A method of making a transfer apparatus includes providing a physical mockup having a shape that corresponds to a positive shape of a patient's dental arch and one or more carrier assemblies that each include a crane body releasably connected to an orthodontic appliance. A transfer apparatus may be formed over the physical mockup, with the transfer tray representing a negative replica of at least a portion of the mockup. The transfer apparatus may be used to seat the appliance on a patient's dental arch, after which point the appliance can be separated from the crane body and bonded to the associated tooth.

CAD-CAM method of mandibular movement transfer to generate individualized 3D printed trajectory guides

Publication No.:  US20260325273A1 22/10/2026
Applicant: 
GONZALEZ MURILLO WENDY CRYSTAL [MX]
GONZALEZ MURILLO Wendy Crystal
US_20260325273_A1

Absstract of: US20260325273A1

This patent refers to a computerized digital method (CAD-CAM) to obtain guides of the trajectories of the jaw movements obtained from each patient integrated into digital predetermined abutments, which can be printed in 3D and integrated into the already known dental articulators. Individualizing the jaw movements synchronized to the dental movements by the already known methods of device tracking using cameras or 3D scanners integrated into software, through CBCT and dental scanning. Through the alignment and individualization of components with the use of specialized software.

ACCELERATION OF MRI EXAMINATIONS OF THE LIVER

Publication No.:  US20260330638A1 22/10/2026
Applicant: 
BAYER AG [DE]
UNIV ESSEN [DE]
BAYER AKTIENGESELLSCHAFT
UNIVERSIT\u00C4TSKLINIKUM ESSEN
US_20260330638_A1

Absstract of: US20260330638A1

The present invention is concerned with the acceleration of an MRI examination of the liver by means of a machine learning model. The machine learning model is configured and trained to predict and MRI image of a liver in the hepatobiliary phase after the application of a hepatobiliary contrast agent on the basis of one or more MRI images which were produced at a time in an earlier phase. The present invention relates to a method for training the machine learning model, to a computer-implemented method for predicting the MRI image in the hepatobiliary phase by means of the trained model, and to a computer system and computer program product for carrying out the prediction method.

Infusion Pump Assembly

Publication No.:  US20260325742A1 22/10/2026
Applicant: 
DEKA PRODUCTS LP [US]
DEKA Products Limited Partnership
US_20260325742_A1

Absstract of: US20260325742A1

0000 A wearable infusion pump assembly. The wearable infusion pump assembly includes a reservoir for receiving an infusible fluid and a fluid delivery system configured to deliver the infusible fluid from the reservoir to an external infusion set. The fluid delivery system includes a controller, a pump assembly for extracting a quantity of infusible fluid from the reservoir and providing the quantity of infusible fluid to the external infusion set, the pump assembly comprising a pump plunger, the pump plunger having distance of travel, the distance of travel having a starting position and an ending position, at least one optical sensor assembly for sensing the starting position and ending position of the pump plunger distance of travel and sending sensor output to the controller, and a first valve assembly configured to selectively isolate the pump assembly from the reservoir, wherein the controller receives the sensor output and determines the total displacement of the pump plunger.

Knee tensioner with digital force and displacement sensing

Publication No.:  AU2026242142A1 22/10/2026
Applicant: 
SMITH & NEPHEW INC
SMITH & NEPHEW ORTHOPAEDICS AG
SMITH & NEPHEW ASIA PACIFIC PTE LTD
Smith & Nephew, Inc.
Smith & Nephew Orthopaedics AG
Smith & Nephew Asia Pacific Pte. Limited
AU_2026242142_A1

Absstract of: AU2026242142A1

A tensioner tool for assessing joint laxity is disclosed. The tensioner tool comprises a pair of pivotally coupled arms, each arm comprising a proximal handle portion, a distal portion, and an insertion tip selectively coupled to the distal portion. The pair of arms pivot between a compressed configuration for insertion within the joint and an expanded configuration for distraction of the joint by applying a force to the handles, thus spreading the insertion tips. The tensioner tool also comprises a force sensor configured to measure the force applied to the handle portion and a positional sensor configured to measure a separation distance between the pair of arms. The tensioner tool also comprises a processor configured to calculate a distraction force at the insertion tips based on the measured force and to calculate a tip distance between the insertion tips based on the measured separation distance. ep e p

RELOCATION MODULE AND METHODS FOR SURGICAL EQUIPMENT

Publication No.:  US20260325382A1 22/10/2026
Applicant: 
AUGUSTINE BIOMEDICAL DESIGN LLC [US]
Augustine Biomedical + Design, LLC
US_20260325382_A1

Absstract of: US20260325382A1

Modules for housing electronic and electromechanical medical equipment including a system to measure and record administration of one or more IV medications or fluids for IV administration.

AN INTRAORAL SCANNING DEVICE WITH A HYGIENIC IMPLEMENTATION OF LEDS

Publication No.:  US20260325267A1 22/10/2026
Applicant: 
3SHAPE AS [DK]
3SHAPE A/S
US_20260325267_A1

Absstract of: US20260325267A1

0000 An intraoral scanning device includes a processing unit configured to process intraoral scan data of a patient and provide 2D image data and/or 3D image data; a wireless interface configured to transmit the 2D image data and/or the 3D image data; a battery configured to power at least the processing unit and the wireless interface, and a housing configured to accommodate at least the processing unit, the wireless interface and at least partially the battery. The intraoral scanning device may further include a plurality of LEDs accommodated by the housing. The plurality of LEDs may be configured to emit light through a transparent part of the housing made of a material that is configured emit the light that passes through the material. The emitted light may indicate a status of the battery and/or the wireless interface, and/or indicate a mode of the intraoral scanning device.

TEXTILE SEAL-FORMING STRUCTURE WITH MULTIPLE CURVATURES

Nº publicación: US20260325780A1 22/10/2026

Applicant:

RESMED PTY LTD [AU]
ResMed Pty Ltd

US_20260325780_A1

Absstract of: US20260325780A1

A patient interface including a seal-forming structure with a textile membrane that has at least one hole such that the flow of air at a therapeutic pressure is delivered to at least an entrance to the patient's nares and/or an entrance to the patient's mouth. The seal-forming structure is constructed and arranged to maintain the therapeutic pressure in a cavity of a plenum chamber throughout the patient's respiratory cycle, in use. The textile membrane includes a first portion that is held in a relaxed state and a second portion that is held in a taut state. The taut state of the second portion is configured to allow the seal-forming structure to include a three-dimensional shape that has multiple curvatures.

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